763003 chr7:45613857:G>A ADCY1 Unknown significance rs369786422 This variant is a VUS because it does not have enough information. 763004 chr7:45613955:C>G ADCY1 Unknown significance rs561544199 This variant is a VUS because it does not have enough information. 0 1322 0 4 1006 0.004 2 694 0.0029 0 1008 0 0 978 0 6 5008 0.00119808 763005 chr7:45614145:G>- ADCY1 NM_021116:c.3delG EXON1 Benign rs567962651 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 4 1322 0.003 0 1006 0 0 694 0 1 1008 0.001 6 978 0.0061 11 5008 0.00219649 763006 chr7:45614242:C>G ADCY1 NM_021116:p.Arg34Gly NM_021116:c.100C>G EXON1 Benign rs760606743 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 0.691 N 0.389 T 0.0 B 0.188742 U 1 N;N -0.384 N 1 4 0.25 0 0 0 0 12 0 0 0 0 0 28 0 0 4 0 0 156 0 1 204 0.00490196 763007 chr7:45614280:G>A ADCY1 NM_021116:p.Glu46Glu NM_021116:c.138G>A EXON1 Unknown significance rs764099850 This variant is a VUS because it does not have enough information. 0 32 0 0 22 0 0 50 0 0 0 0 1 402 0.00248756 0 26 0 0 1416 0 1 1948 0.000513347 763008 chr7:45614307:G>A ADCY1 NM_021116:p.Arg55Arg NM_021116:c.165G>A EXON1 Unknown significance rs753933695 This variant is a VUS because it does not have enough information. 0 56 0 0 28 0 0 60 0 0 2 0 1 534 0.00187266 0 34 0 0 2008 0 1 2722 0.000367377 763009 chr7:45614312:A>G ADCY1 NM_021116:p.Glu57Gly NM_021116:c.170A>G EXON1 Unknown significance rs552168629 This variant is a VUS because it does not have enough information. 0.092 N 0.059 T 0.996 D 0 D 0.999454 D;D 2.81 C 763010 chr7:45614346:C>T ADCY1 NM_021116:p.Leu68Leu NM_021116:c.204C>T EXON1 Unknown significance rs531991756 This variant is a VUS because it does not have enough information. 0 1322 0 2 1006 0.002 1 694 0.0014 0 1008 0 0 978 0 3 5008 0.000599042 0 64 0 0 38 0 0 54 0 0 58 0 0 538 0 0 34 0 0 2508 0 0 3294 0 763011 chr7:45614359:G>A ADCY1 NM_021116:p.Gly73Ser NM_021116:c.217G>A EXON1 Likely benign rs544024276 Pathogenicity is based on prediction data only. 2 out of 6 predictions were pathogenic. 0.875 N 0.494 T 0.003 B 0.028641 N 0.987602 D;D 3.96 C 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763012 chr7:45614376:C>A ADCY1 NM_021116:p.Ala78Ala NM_021116:c.234C>A EXON1 Benign rs74641956 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 0 276 0 0 108 0 4 256 0.015625 0 366 0 0 2540 0 0 84 0 0 4932 0 4 8562 0.000467181 763013 chr7:45614376:C>G ADCY1 NM_021116:p.Ala78Ala NM_021116:c.234C>G EXON1 Benign rs74641956 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 1 1322 0.0008 18 1006 0.0179 6 694 0.0086 0 1008 0 0 978 0 25 5008 0.00499201 4 276 0.0144928 4 108 0.037037 0 256 0 20 366 0.0546448 240 2540 0.0944882 1 84 0.0119048 19 4932 0.00385239 288 8562 0.033637 763014 chr7:45614388:C>A ADCY1 NM_021116:p.Gly82Gly NM_021116:c.246C>A EXON1 Unknown significance rs758855790 This variant is a VUS because it does not have enough information. 1 930 0.00107527 0 578 0 0 978 0 0 550 0 0 6586 0 0 166 0 0 7046 0 1 16834 5.94036e-05 763015 chr7:45614390:C>T ADCY1 NM_021116:p.Ala83Val NM_021116:c.248C>T EXON1 Benign rs375141353 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 0.783 N 0.317 T 0.715 P 0.324801 N 1 D;N 0.505 C 0 1322 0 0 1006 0 0 694 0 0 1008 0 8 978 0.0082 8 5008 0.00159744 0 1134 0 1 754 0.00132626 0 1228 0 0 820 0 0 8144 0 1 190 0.00526316 115 7668 0.0149974 117 19938 0.00586819 763016 chr7:45614391:G>T ADCY1 NM_021116:p.Ala83Ala NM_021116:c.249G>T EXON1 Unknown significance rs747493330 This variant is a VUS because it does not have enough information. 0 1340 0 0 932 0 1 1424 0.000702247 0 1012 0 0 9664 0 0 200 0 0 8134 0 1 22706 4.40412e-05 763017 chr7:45614392:C>T ADCY1 NM_021116:p.Pro84Ser NM_021116:c.250C>T EXON1 Unknown significance rs79229229 This variant is a VUS because it does not have enough information. 0.783 N 0.436 T 0.759 P 1.1e-05 D 0.852915 D;D 3.69 C 763018 chr7:45614400:C>G ADCY1 NM_021116:p.Pro86Pro NM_021116:c.258C>G EXON1 Benign rs200597993 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 1 1322 0.0008 1 1006 0.001 2 694 0.0029 0 1008 0 1 978 0.001 5 5008 0.000998403 2 2838 0.000704722 1 3068 0.000325945 0 3356 0 0 1930 0 40 22654 0.00176569 0 336 0 105 10216 0.010278 148 44398 0.00333348 763019 chr7:45614400:C>T ADCY1 NM_021116:p.Pro86Pro NM_021116:c.258C>T EXON1 Unknown significance rs200597993 This variant is a VUS because it does not have enough information. 0 2838 0 0 3068 0 0 3356 0 0 1930 0 1 22654 4.41423e-05 1 336 0.00297619 0 10216 0 2 44398 4.50471e-05 763020 chr7:45614401:G>C ADCY1 NM_021116:p.Ala87Pro NM_021116:c.259G>C EXON1 Unknown significance rs748845827 This variant is a VUS because it does not have enough information. 0.874 N 0.142 T 0.574 P 0.00026 D 0.703355 D;D 2.8 C 0 2956 0 0 3310 0 0 3524 0 0 1956 0 1 24142 4.14216e-05 0 346 0 0 10406 0 1 46640 2.14408e-05 763021 chr7:45614405:C>T ADCY1 NM_021116:p.Pro88Leu NM_021116:c.263C>T EXON1 Likely benign rs770682134 Pathogenicity is based on prediction data only. 2 out of 6 predictions were pathogenic. -0.068 N 0.662 T 0.0 B 0.007712 N 0.986981 D;D 2.8 C 0 3980 0 2 5362 0.000372995 0 4798 0 0 2816 0 0 33858 0 0 452 0 0 11588 0 2 62854 3.18198e-05 763022 chr7:45614407:G>A ADCY1 NM_021116:p.Gly89Ser NM_021116:c.265G>A EXON1 Unknown significance rs79204521 This variant is a VUS because it does not have enough information. 0.874 N 0.424 T 0.014 B 0.000142 D 1 D;N 2.69 C 763023 chr7:45614410:C>G ADCY1 NM_021116:p.Leu90Val NM_021116:c.268C>G EXON1 Unknown significance rs774107345 This variant is a VUS because it does not have enough information. 0.792 N 0.25 T 0.006 B 0.000117 D 1 D;N 3.69 C 0 5234 0 0 7780 0 0 6164 0 0 3810 0 1 44284 2.25815e-05 0 570 0 0 12858 0 1 80700 1.23916e-05 763024 chr7:45614414:C>T ADCY1 NM_021116:p.Ala91Val NM_021116:c.272C>T EXON1 Unknown significance rs77566296 This variant is a VUS because it does not have enough information. 0.792 N 0.64 T 0.501 P 1e-05 D 0.962163 D;D 2.8 C 763025 chr7:45614417:A>G ADCY1 NM_021116:p.Lys92Arg NM_021116:c.275A>G EXON1 Likely benign rs745641221 Pathogenicity is based on prediction data only. 2 out of 6 predictions were pathogenic. 0.097 N 0.486 T 0.002 B 8e-06 N 0.998817 D;D 2.53 C 0 6360 0 0 9694 0 0 7348 0 0 4790 0 0 52796 0 1 684 0.00146199 0 14118 0 1 95790 1.04395e-05 763026 chr7:45614419:G>T ADCY1 NM_021116:p.Gly93Cys NM_021116:c.277G>T EXON1 Unknown significance rs771838265 This variant is a VUS because it does not have enough information. 0.884 N 0.163 T 1.0 D 0 D 0.999989 D;D 3.69 C 0 6546 0 0 9984 0 0 7514 0 0 4952 0 1 54064 1.84966e-05 0 700 0 0 14356 0 1 98116 1.0192e-05 763027 chr7:45614430:G>A ADCY1 NM_021116:p.Pro96Pro NM_021116:c.288G>A EXON1 Unknown significance rs775165471 This variant is a VUS because it does not have enough information. 0 7452 0 0 10840 0 0 8102 0 0 5688 0 1 58884 1.69825e-05 0 776 0 0 15454 0 1 107196 9.32871e-06 763028 chr7:45614439:C>T ADCY1 NM_021116:p.Cys99Cys NM_021116:c.297C>T EXON1 Unknown significance rs776113547 This variant is a VUS because it does not have enough information. 0 7900 0 0 11036 0 0 8236 0 0 6046 0 1 60458 1.65404e-05 0 792 0 0 15888 0 1 110356 9.06158e-06 763029 chr7:45614440:G>A ADCY1 NM_021116:p.Val100Ile NM_021116:c.298G>A EXON1 Likely benign rs764052766 Pathogenicity is based on prediction data only. 2 out of 6 predictions were pathogenic. 0.045 N 0.83 T 0.003 B 0.002557 N 1 D;N 1.58 C 0 7950 0 0 11056 0 0 8248 0 0 6086 0 0 60648 0 0 798 0 1 15930 6.27746e-05 1 110716 9.03212e-06 763030 chr7:45614440:G>C ADCY1 NM_021116:p.Val100Leu NM_021116:c.298G>C EXON1 Likely benign rs764052766 Pathogenicity is based on prediction data only. 2 out of 6 predictions were pathogenic. 0.045 N 0.47 T 0.079 B 0.002557 N 1 D;N 1.58 C 0 7950 0 0 11056 0 0 8248 0 0 6086 0 1 60648 1.64886e-05 0 798 0 0 15930 0 1 110716 9.03212e-06 763031 chr7:45614442:C>T ADCY1 NM_021116:p.Val100Val NM_021116:c.300C>T EXON1 Unknown significance rs761931194 This variant is a VUS because it does not have enough information. 0 8038 0 0 11084 0 0 8266 0 0 6142 0 1 60856 1.64322e-05 0 804 0 1 15974 6.26017e-05 2 111164 1.79914e-05 763032 chr7:45614454:G>A ADCY1 NM_021116:p.Ala104Ala NM_021116:c.312G>A EXON1 Unknown significance rs765365053 This variant is a VUS because it does not have enough information. 0 8236 0 0 11182 0 0 8306 0 0 6318 0 1 61504 1.62591e-05 0 824 0 0 16170 0 1 112540 8.88573e-06 763033 chr7:45614461:G>C ADCY1 NM_021116:p.Val107Leu NM_021116:c.319G>C EXON1 Unknown significance rs200378809 This variant is a VUS because it does not have enough information. 0.884 N 0.08 T 0.002 B 5.5e-05 D 0.988785 D;D 2.47 C 0 8322 0 0 11214 0 0 8316 0 1 6394 0.000156397 0 61686 0 0 836 0 0 16226 0 1 112994 8.85003e-06 763034 chr7:45614461:G>T ADCY1 NM_021116:p.Val107Leu NM_021116:c.319G>T EXON1 Unknown significance rs200378809 This variant is a VUS because it does not have enough information. 0.884 N 0.08 T 0.002 B 5.5e-05 D 0.989214 D;D 2.47 C 0 8322 0 0 11214 0 2 8316 0.0002405 0 6394 0 0 61686 0 0 836 0 0 16226 0 2 112994 1.77001e-05 763035 chr7:45614472:CGT>- ADCY1 NM_021116:c.330_332delCGT EXON1 Unknown significance rs761370974 This variant is a VUS because it does not have enough information. 763036 chr7:45614482:C>T ADCY1 NM_021116:p.Leu114Leu NM_021116:c.340C>T EXON1 Unknown significance rs766716634 This variant is a VUS because it does not have enough information. 0 8392 0 0 11258 0 0 8346 0 0 6450 0 0 61860 0 0 832 0 1 16280 6.14251e-05 1 113418 8.81694e-06 763037 chr7:45614499:G>A ADCY1 NM_021116:p.Leu119Leu NM_021116:c.357G>A EXON1 Unknown significance rs752002367 This variant is a VUS because it does not have enough information. 0 8442 0 0 11272 0 0 8342 0 0 6456 0 1 61946 1.61431e-05 0 838 0 0 16274 0 1 113570 8.80514e-06 763038 chr7:45614508:C>T ADCY1 NM_021116:p.Val122Val NM_021116:c.366C>T EXON1 Unknown significance rs755508070 This variant is a VUS because it does not have enough information. 0 8486 0 0 11268 0 0 8332 0 0 6442 0 0 61962 0 0 842 0 1 16274 6.14477e-05 1 113606 8.80235e-06 763039 chr7:45614533:C>T ADCY1 NM_021116:p.Leu131Phe NM_021116:c.391C>T EXON1 Unknown significance rs781776242 This variant is a VUS because it does not have enough information. 0.792 N 0.3 T 0.0 B 1.3e-05 D 0.886263 D;D 2.55 C 0 8490 0 0 11234 0 0 8328 0 0 6416 0 0 61802 0 0 842 0 1 16240 6.15764e-05 1 113352 8.82208e-06 763040 chr7:45614535:C>G ADCY1 NM_021116:p.Leu131Leu NM_021116:c.393C>G EXON1 Unknown significance rs753381717 This variant is a VUS because it does not have enough information. 0 8480 0 0 11234 0 0 8328 0 0 6412 0 0 61774 0 0 842 0 2 16232 0.000123213 2 113302 1.76519e-05 763041 chr7:45614544:G>T ADCY1 NM_021116:p.Ala134Ala NM_021116:c.402G>T EXON1 Unknown significance rs756854830 This variant is a VUS because it does not have enough information. 0 8356 0 0 11202 0 0 8290 0 0 6364 0 0 61458 0 0 836 0 1 16196 6.17436e-05 1 112702 8.87296e-06 763043 chr7:45614550:C>T ADCY1 NM_021116:p.Leu136Leu NM_021116:c.408C>T EXON1 Unknown significance rs778295490 This variant is a VUS because it does not have enough information. 0 8332 0 1 11178 8.94614e-05 0 8272 0 0 6366 0 0 61312 0 0 834 0 0 16182 0 1 112476 8.89079e-06 763042 chr7:45614551:->CCCTTACA ADCY1 NM_021116:c.409_410insCCCTTACA EXON1 Unknown significance rs767679562 This variant is a VUS because it does not have enough information. 0 8332 0 0 11178 0 0 8272 0 0 6366 0 1 61312 1.631e-05 0 834 0 0 16182 0 1 112476 8.89079e-06 763044 chr7:45614553:->TAATCATCCAAATGGGAGTGGGTGGT ADCY1 NM_021116:c.411_412insTAATCATCCAAATGGGAGTGGGTGGT EXON1 Unknown significance rs750467665 This variant is a VUS because it does not have enough information. 0 8288 0 0 11148 0 0 8264 0 0 6350 0 1 61116 1.63623e-05 0 830 0 0 16188 0 1 112184 8.91393e-06 763045 chr7:45614555:->A ADCY1 NM_021116:c.413_414insA EXON1 Unknown significance rs761016108 This variant is a VUS because it does not have enough information. 0 8242 0 0 11146 0 0 8250 0 0 6340 0 1 60870 1.64285e-05 0 830 0 0 16162 0 1 111840 8.94134e-06 763046 chr7:45614556:T>C ADCY1 NM_021116:p.Cys138Cys NM_021116:c.414T>C EXON1 Unknown significance rs745471312 This variant is a VUS because it does not have enough information. 0 8208 0 0 11128 0 0 8240 0 0 6334 0 1 60674 1.64815e-05 0 828 0 0 16148 0 1 111560 8.96379e-06 763047 chr7:45614562:C>G ADCY1 NM_021116:p.Phe140Leu NM_021116:c.420C>G EXON1 Likely benign rs771648046 Pathogenicity is based on prediction data only. 1 out of 6 predictions were pathogenic. -0.061 N 1.0 T 0.006 B 6e-06 N 0.983344 D;D -4.67 N 1 8008 0.000124875 0 11078 0 0 8142 0 0 6304 0 0 59560 0 0 812 0 0 16112 0 1 110016 9.08959e-06 763048 chr7:45614563:G>T ADCY1 NM_021116:p.Ala141Ser NM_021116:c.421G>T EXON1 Unknown significance rs779862034 This variant is a VUS because it does not have enough information. 0.884 N 0.524 T 0.014 B 4.1e-05 D 1 D;N 1.46 C 0 7962 0 0 11082 0 0 8130 0 0 6292 0 1 59334 1.68537e-05 0 812 0 0 16094 0 1 109706 9.11527e-06 763049 chr7:45614565:G>C ADCY1 NM_021116:p.Ala141Ala NM_021116:c.423G>C EXON1 Unknown significance rs746848171 This variant is a VUS because it does not have enough information. 0 7972 0 0 11066 0 0 8130 0 0 6294 0 6 59344 0.000101105 0 812 0 3 16106 0.000186266 9 109724 8.2024e-05 763050 chr7:45614565:G>T ADCY1 NM_021116:p.Ala141Ala NM_021116:c.423G>T EXON1 Unknown significance rs746848171 This variant is a VUS because it does not have enough information. 0 7972 0 0 11066 0 0 8130 0 0 6294 0 1 59344 1.68509e-05 0 812 0 0 16106 0 1 109724 9.11378e-06 763051 chr7:45614571:C>G ADCY1 NM_021116:p.Gly143Gly NM_021116:c.429C>G EXON1 Unknown significance rs764921404 This variant is a VUS because it does not have enough information. 763052 chr7:45614576:C>T ADCY1 NM_021116:p.Pro145Leu NM_021116:c.434C>T EXON1 Unknown significance rs776609542 This variant is a VUS because it does not have enough information. 0.792 N 0.026 D 0.137 B 0.00339 N 0.997957 D;D 2.84 C 0 7702 0 0 10956 0 0 8018 0 0 6240 0 2 57924 3.4528e-05 0 794 0 0 16058 0 2 107692 1.85715e-05 763053 chr7:45614582:G>A ADCY1 NM_021116:p.Arg147Gln NM_021116:c.440G>A EXON1 Likely benign rs761877943 Pathogenicity is based on prediction data only. 2 out of 5 predictions were pathogenic. 0.884 N 0.593 T 0.178 B 0.92601 U 0.99998 D;N 2.84 C 0 7624 0 0 10932 0 0 7988 0 0 6218 0 0 57626 0 0 794 0 1 16060 6.22665e-05 1 107242 9.3247e-06 763054 chr7:45614582:G>C ADCY1 NM_021116:p.Arg147Pro NM_021116:c.440G>C EXON1 Likely benign rs761877943 Pathogenicity is based on prediction data only. 2 out of 5 predictions were pathogenic. 0.884 N 0.309 T 0.165 B 0.92601 U 0.999984 D;N 2.84 C 0 7624 0 0 10932 0 1 7988 0.000125188 0 6218 0 0 57626 0 0 794 0 0 16060 0 1 107242 9.3247e-06 763055 chr7:45614595:G>C ADCY1 NM_021116:p.Gly151Gly NM_021116:c.453G>C EXON1 Unknown significance rs773187376 This variant is a VUS because it does not have enough information. 0 7590 0 0 10888 0 0 7928 0 0 6162 0 0 57274 0 0 784 0 1 16056 6.2282e-05 1 106682 9.37365e-06 763056 chr7:45614603:G>T ADCY1 NM_021116:p.Gly154Val NM_021116:c.461G>T EXON1 Likely benign rs763194212 Pathogenicity is based on prediction data only. 0 out of 6 predictions were pathogenic. -0.976 N 0.354 T 0.0 B 0.169948 N 0.999999 N;N -0.53 N 0 7632 0 0 10866 0 2 7930 0.000252207 0 6168 0 0 57376 0 0 780 0 0 16048 0 2 106800 1.87266e-05 763057 chr7:45614604:G>A ADCY1 NM_021116:p.Gly154Gly NM_021116:c.462G>A EXON1 Unknown significance rs766548504 This variant is a VUS because it does not have enough information. 0 7702 0 0 10898 0 0 7956 0 0 6178 0 3 57516 5.21594e-05 0 790 0 0 16066 0 3 107106 2.80096e-05 763058 chr7:45614605:G>A ADCY1 NM_021116:p.Gly155Arg NM_021116:c.463G>A EXON1 Likely benign rs751947495 Pathogenicity is based on prediction data only. 1 out of 6 predictions were pathogenic. 0.884 N 0.543 T 0.0 B 0.001985 N 0.999974 N;N 2.7 C 0 7704 0 0 10900 0 0 7948 0 0 6162 0 1 57510 1.73883e-05 0 790 0 0 16070 0 1 107084 9.33846e-06 763059 chr7:45614636:A>C ADCY1 NM_021116:p.Gln165Pro NM_021116:c.494A>C EXON1 Unknown significance rs760033357 This variant is a VUS because it does not have enough information. 1.011 C 0.266 T 0.002 B 0 D 0.999975 D;D 3.7 C 0 8412 0 0 11024 0 0 8156 0 0 6242 0 1 59438 1.68243e-05 0 812 0 0 16144 0 1 110228 9.07211e-06 763060 chr7:45614643:T>G ADCY1 NM_021116:p.Leu167Leu NM_021116:c.501T>G EXON1 Unknown significance rs376573772 This variant is a VUS because it does not have enough information. 1 8548 0.000116986 0 4382 0 1 12930 7.73395e-05 763061 chr7:45614652:C>T ADCY1 NM_021116:p.Thr170Thr NM_021116:c.510C>T EXON1 Unknown significance rs370830411 This variant is a VUS because it does not have enough information. 0 8556 0 1 4390 0.00022779 1 12946 7.72439e-05 1 8642 0.000115714 0 11092 0 0 8272 0 0 6268 0 0 60340 0 0 818 0 0 16166 0 1 111598 8.96073e-06 763062 chr7:45614663:A>G ADCY1 NM_021116:p.Tyr174Cys NM_021116:c.521A>G EXON1 Unknown significance rs753183956 This variant is a VUS because it does not have enough information. 1.011 C 0.001 D 0.999 D 2e-06 D 0.999999 D;D 3.7 C 0 8758 0 0 11146 0 0 8326 0 0 6284 0 0 60848 0 0 820 0 1 16192 6.17589e-05 1 112374 8.89886e-06 763063 chr7:45614671:C>A ADCY1 NM_021116:p.Leu177Met NM_021116:c.529C>A EXON1 Unknown significance rs756596808 This variant is a VUS because it does not have enough information. 0.797 N 0.293 T 0.996 D 2.1e-05 D 0.999722 D;D 3.7 C 0 8794 0 0 11154 0 0 8342 0 0 6298 0 1 61004 1.63924e-05 0 820 0 0 16196 0 1 112608 8.88036e-06 763064 chr7:45614685:C>A ADCY1 NM_021116:p.Ser181Arg NM_021116:c.543C>A EXON1 Unknown significance rs778441100 This variant is a VUS because it does not have enough information. 0.797 N 0.022 D 0.009 B 6e-06 D 1 D;N 2.56 C 0 8866 0 0 11210 0 1 8384 0.000119275 0 6282 0 0 61292 0 0 820 0 0 16186 0 1 113040 8.84643e-06 763065 chr7:45614685:C>G ADCY1 NM_021116:p.Ser181Arg NM_021116:c.543C>G EXON1 Unknown significance rs778441100 This variant is a VUS because it does not have enough information. 0.797 N 0.022 D 0.009 B 6e-06 D 1 D;N 2.56 C 0 8866 0 0 11210 0 0 8384 0 0 6282 0 0 61292 0 0 820 0 2 16186 0.000123564 2 113040 1.76929e-05 763066 chr7:45614693:C>T ADCY1 NM_021116:p.Ala184Val NM_021116:c.551C>T EXON1 Unknown significance rs758041210 This variant is a VUS because it does not have enough information. -0.019 N 0.002 D 0.907 P 0.000251 N 0.999979 D;D 1.88 C 0 8900 0 0 11228 0 0 8398 0 0 6296 0 1 61416 1.62824e-05 0 830 0 0 16162 0 1 113230 8.83158e-06 763067 chr7:45614697:A>G ADCY1 NM_021116:p.Ile185Met NM_021116:c.555A>G EXON1 Unknown significance rs779732430 This variant is a VUS because it does not have enough information. -0.022 N 0.006 D 0.311 B 3.2e-05 D 0.995697 D;D 3.7 C 0 8914 0 0 11220 0 0 8400 0 0 6302 0 1 61478 1.6266e-05 0 828 0 0 16154 0 1 113296 8.82644e-06 763068 chr7:45614707:C>T ADCY1 NM_021116:p.Leu189Phe NM_021116:c.565C>T EXON1 Likely benign rs765505992 Pathogenicity is based on prediction data only. 2 out of 6 predictions were pathogenic. 0.797 N 0.259 T 0.011 B 0.049104 N 0.898464 D;D 2.71 C 0 8794 0 0 11216 0 0 8400 0 0 6270 0 1 61338 1.63031e-05 0 826 0 0 16088 0 1 112932 8.85489e-06 763069 chr7:45614709:C>T ADCY1 NM_021116:p.Leu189Leu NM_021116:c.567C>T EXON1 Unknown significance rs768506366 This variant is a VUS because it does not have enough information. 1 8816 0.00011343 0 11222 0 0 8394 0 0 6270 0 0 61364 0 0 824 0 0 16092 0 1 112982 8.85097e-06 763070 chr7:45614742:C>T ADCY1 NM_021116:p.Ala200Ala NM_021116:c.600C>T EXON1 Unknown significance rs780969675 This variant is a VUS because it does not have enough information. 0 8754 0 1 11280 8.86525e-05 0 8436 0 0 6288 0 0 61204 0 0 818 0 0 15284 0 1 112064 8.92347e-06 763071 chr7:45614744:C>T ADCY1 NM_021116:p.Thr201Ile NM_021116:c.602C>T EXON1 Unknown significance rs748029352 This variant is a VUS because it does not have enough information. 0.864 N 0.398 T 0.001 B 0.000189 D 0.970849 D;D 3.7 C 0 8726 0 0 11274 0 0 8442 0 0 6290 0 1 61188 1.63431e-05 0 816 0 0 15180 0 1 111916 8.93527e-06 763072 chr7:45614757:C>T ADCY1 NM_021116:p.Ala205Ala NM_021116:c.615C>T EXON1 Unknown significance rs139122316 This variant is a VUS because it does not have enough information. 1 8568 0.000116713 0 4386 0 1 12954 7.71962e-05 763073 chr7:45614796:G>A ADCY1 NM_021116:c.639+15G>A INTRON1 Unknown significance rs769649414 This variant is a VUS because it does not have enough information. 0 8342 0 2 11184 0.000178827 0 8390 0 0 6216 0 0 59842 0 0 738 0 0 11354 0 2 106066 1.88562e-05 763074 chr7:45614798:A>T ADCY1 NM_021116:c.639+17A>T INTRON1 Unknown significance rs773309750 This variant is a VUS because it does not have enough information. 0 8308 0 0 11188 0 0 8382 0 0 6200 0 10 59778 0.000167286 0 734 0 0 11196 0 10 105786 9.45305e-05 763075 chr7:45614807:C>G ADCY1 NM_021116:c.639+26C>G INTRON1 Unknown significance rs199544733 This variant is a VUS because it does not have enough information. 0 8504 0 5 4360 0.00114679 5 12864 0.000388682 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 19 8238 0.00230639 3 11174 0.00026848 0 8356 0 0 6202 0 0 59428 0 0 722 0 0 10448 0 22 104568 0.000210389 763076 chr7:45614814:C>G ADCY1 NM_021116:c.639+33C>G INTRON1 Unknown significance rs771168252 This variant is a VUS because it does not have enough information. 1 8184 0.00012219 0 11154 0 0 8346 0 0 6180 0 0 59210 0 0 716 0 0 9976 0 1 103766 9.63707e-06 763077 chr7:45614817:A>G ADCY1 NM_021116:c.639+36A>G INTRON1 Unknown significance rs774777802 This variant is a VUS because it does not have enough information. 0 8148 0 0 11152 0 0 8338 0 0 6172 0 1 59176 1.68987e-05 0 710 0 0 9772 0 1 103468 9.66482e-06 763078 chr7:45614822:C>T ADCY1 NM_021116:c.639+41C>T INTRON1 Unknown significance rs759838946 This variant is a VUS because it does not have enough information. 0 8048 0 0 11128 0 0 8322 0 0 6126 0 0 58940 0 0 706 0 1 9422 0.000106135 1 102692 9.73786e-06 763079 chr7:45614823:T>C ADCY1 NM_021116:c.639+42T>C INTRON1 Unknown significance rs767939227 This variant is a VUS because it does not have enough information. 1 8056 0.000124131 0 11122 0 0 8318 0 0 6142 0 0 58958 0 0 708 0 0 9446 0 1 102750 9.73236e-06 763080 chr7:45614825:G>A ADCY1 NM_021116:c.639+44G>A INTRON1 Unknown significance rs776023135 This variant is a VUS because it does not have enough information. 0 8010 0 0 11122 0 0 8308 0 0 6134 0 2 58882 3.39662e-05 0 708 0 0 9406 0 2 102570 1.94989e-05 763081 chr7:45614826:C>G ADCY1 NM_021116:c.639+45C>G INTRON1 Unknown significance rs761208011 This variant is a VUS because it does not have enough information. 0 7996 0 0 11118 0 0 8300 0 1 6114 0.000163559 0 58784 0 0 700 0 0 9298 0 1 102310 9.77422e-06 763082 chr7:45614828:G>A ADCY1 NM_021116:c.639+47G>A INTRON1 Unknown significance rs764551512 This variant is a VUS because it does not have enough information. 0 7962 0 0 11104 0 0 8292 0 0 6112 0 0 58676 0 0 706 0 0 9246 0 0 102098 0 763083 chr7:45614848:C>G ADCY1 NM_021116:c.639+67C>G INTRON1 Unknown significance rs529625280 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763084 chr7:45614859:G>A ADCY1 NM_021116:c.639+78G>A INTRON1 Unknown significance rs548105209 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 763085 chr7:45614874:C>T ADCY1 NM_021116:c.639+93C>T INTRON1 Unknown significance rs569611079 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 2 978 0.002 2 5008 0.000399361 763086 chr7:45614875:G>A ADCY1 NM_021116:c.639+94G>A INTRON1 Benign rs73318930 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 29 1322 0.0219 38 1006 0.0378 22 694 0.0317 0 1008 0 10 978 0.0102 99 5008 0.0197684 763087 chr7:45614906:G>A ADCY1 NM_021116:c.639+125G>A INTRON1 Unknown significance rs568560081 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681 763088 chr7:45614925:C>G ADCY1 NM_021116:c.639+144C>G INTRON1 Unknown significance rs570597916 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681 763089 chr7:45614927:A>G ADCY1 NM_021116:c.639+146A>G INTRON1 Unknown significance rs538774158 This variant is a VUS because it does not have enough information. 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403 763090 chr7:45614958:C>G ADCY1 NM_021116:c.639+177C>G INTRON1 Unknown significance rs554225387 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 1 978 0.001 2 5008 0.000399361 763091 chr7:45614985:C>A ADCY1 NM_021116:c.639+204C>A INTRON1 Unknown significance rs528174506 This variant is a VUS because it does not have enough information. 763092 chr7:45615035:G>A ADCY1 NM_021116:c.639+254G>A INTRON1 Unknown significance rs572378362 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 4 1008 0.004 0 978 0 4 5008 0.000798722 763093 chr7:45615063:G>C ADCY1 NM_021116:c.639+282G>C INTRON1 Unknown significance rs763312122 This variant is a VUS because it does not have enough information. 763094 chr7:45615114:C>T ADCY1 NM_021116:c.639+333C>T INTRON1 Unknown significance rs543041940 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681 763095 chr7:45615137:T>G ADCY1 NM_021116:c.639+356T>G INTRON1 Unknown significance rs764326617 This variant is a VUS because it does not have enough information. 763096 chr7:45615164:C>G ADCY1 NM_021116:c.639+383C>G INTRON1 Unknown significance rs752132116 This variant is a VUS because it does not have enough information. 763097 chr7:45615175:C>T ADCY1 NM_021116:c.639+394C>T INTRON1 Unknown significance rs555345101 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681 763098 chr7:45615183:G>A ADCY1 NM_021116:c.639+402G>A INTRON1 Benign rs373380741 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 0 1322 0 0 1006 0 0 694 0 6 1008 0.006 0 978 0 6 5008 0.00119808 763099 chr7:45615185:C>G ADCY1 NM_021116:c.639+404C>G INTRON1 Benign rs12702148 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 81 1322 0.0613 313 1006 0.3111 199 694 0.2867 474 1008 0.4702 345 978 0.3528 1412 5008 0.281949 763100 chr7:45615193:G>A ADCY1 NM_021116:c.639+412G>A INTRON1 Unknown significance rs375745430 This variant is a VUS because it does not have enough information. 763101 chr7:45615209:C>A ADCY1 NM_021116:c.639+428C>A INTRON1 Unknown significance rs565357511 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681 763102 chr7:45615249:C>T ADCY1 NM_021116:c.639+468C>T INTRON1 Unknown significance rs184559465 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 763103 chr7:45615260:C>T ADCY1 NM_021116:c.639+479C>T INTRON1 Benign rs145162581 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 0 1322 0 12 1006 0.0119 2 694 0.0029 0 1008 0 6 978 0.0061 20 5008 0.00399361 763104 chr7:45615264:G>T ADCY1 NM_021116:c.639+483G>T INTRON1 Unknown significance rs751487247 This variant is a VUS because it does not have enough information. 763105 chr7:45615289:A>T ADCY1 NM_021116:c.639+508A>T INTRON1 Unknown significance rs559375449 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 763106 chr7:45615303:A>C ADCY1 NM_021116:c.639+522A>C INTRON1 Unknown significance rs369011235 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763107 chr7:45615333:C>T ADCY1 NM_021116:c.639+552C>T INTRON1 Unknown significance rs749959431 This variant is a VUS because it does not have enough information. 763108 chr7:45615382:C>T ADCY1 NM_021116:c.639+601C>T INTRON1 Benign rs189331207 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 14 1322 0.0106 0 1006 0 0 694 0 0 1008 0 0 978 0 14 5008 0.00279553 763109 chr7:45615385:T>A ADCY1 NM_021116:c.639+604T>A INTRON1 Unknown significance rs755627358 This variant is a VUS because it does not have enough information. 763110 chr7:45615399:G>C ADCY1 NM_021116:c.639+618G>C INTRON1 Unknown significance rs779853539 This variant is a VUS because it does not have enough information. 763111 chr7:45615402:G>- ADCY1 NM_021116:c.639+621delG INTRON1 Unknown significance rs534965150 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 2 1008 0.002 0 978 0 3 5008 0.000599042 763112 chr7:45615460:C>T ADCY1 NM_021116:c.639+679C>T INTRON1 Unknown significance rs562902921 This variant is a VUS because it does not have enough information. 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403 763113 chr7:45615478:G>C ADCY1 NM_021116:c.639+697G>C INTRON1 Unknown significance rs369341105 This variant is a VUS because it does not have enough information. 763114 chr7:45615481:C>T ADCY1 NM_021116:c.639+700C>T INTRON1 Unknown significance rs370121629 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 4 1008 0.004 0 978 0 4 5008 0.000798722 763115 chr7:45615482:G>A ADCY1 NM_021116:c.639+701G>A INTRON1 Unknown significance rs552414012 This variant is a VUS because it does not have enough information. 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361 763116 chr7:45615605:T>C ADCY1 NM_021116:c.639+824T>C INTRON1 Benign rs181985809 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 4 1322 0.003 28 1006 0.0278 5 694 0.0072 10 1008 0.0099 101 978 0.1033 148 5008 0.0295527 763117 chr7:45615617:C>T ADCY1 NM_021116:c.639+836C>T INTRON1 Unknown significance rs556886268 This variant is a VUS because it does not have enough information. 763118 chr7:45615627:G>A ADCY1 NM_021116:c.639+846G>A INTRON1 Benign rs7804852 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 32 1322 0.0242 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 34 5008 0.00678914 763119 chr7:45615628:C>T ADCY1 NM_021116:c.639+847C>T INTRON1 Benign rs7804581 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 32 1322 0.0242 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 34 5008 0.00678914 763120 chr7:45615646:G>- ADCY1 NM_021116:c.639+865delG INTRON1 Unknown significance rs200909534 This variant is a VUS because it does not have enough information. 763121 chr7:45615647:T>- ADCY1 NM_021116:c.639+866delT INTRON1 Benign rs11339042 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 685 1322 0.5182 482 1006 0.4791 294 694 0.4236 673 1008 0.6677 603 978 0.6166 2737 5008 0.546526 763122 chr7:45615648:T>G ADCY1 NM_021116:c.639+867T>G INTRON1 Unknown significance rs199943201 This variant is a VUS because it does not have enough information. 763123 chr7:45615676:G>A ADCY1 NM_021116:c.639+895G>A INTRON1 Unknown significance rs113821653 This variant is a VUS because it does not have enough information. 763124 chr7:45615704:G>T ADCY1 NM_021116:c.639+923G>T INTRON1 Unknown significance rs566171167 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763125 chr7:45615707:G>T ADCY1 NM_021116:c.639+926G>T INTRON1 Unknown significance rs754839666 This variant is a VUS because it does not have enough information. 763126 chr7:45615757:C>T ADCY1 NM_021116:c.639+976C>T INTRON1 Unknown significance rs778618608 This variant is a VUS because it does not have enough information. 763127 chr7:45615765:A>G ADCY1 NM_021116:c.639+984A>G INTRON1 Unknown significance rs539366781 This variant is a VUS because it does not have enough information. 763128 chr7:45615783:C>T ADCY1 NM_021116:c.639+1002C>T INTRON1 Benign rs12702149 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 264 1322 0.1997 400 1006 0.3976 251 694 0.3617 662 1008 0.6567 494 978 0.5051 2071 5008 0.413538 763129 chr7:45615797:GG>- ADCY1 NM_021116:c.639+1016_639+1017delGG INTRON1 Unknown significance rs758751673 This variant is a VUS because it does not have enough information. 763130 chr7:45615803:G>A ADCY1 NM_021116:c.639+1022G>A INTRON1 Unknown significance rs555009719 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763131 chr7:45615823:A>G ADCY1 NM_021116:c.639+1042A>G INTRON1 Unknown significance rs576474066 This variant is a VUS because it does not have enough information. 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403 763132 chr7:45615829:T>A ADCY1 NM_021116:c.639+1048T>A INTRON1 Unknown significance rs537357782 This variant is a VUS because it does not have enough information. 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042 763133 chr7:45615842:C>G ADCY1 NM_021116:c.639+1061C>G INTRON1 Unknown significance rs565848865 This variant is a VUS because it does not have enough information. 763134 chr7:45615851:G>A ADCY1 NM_021116:c.639+1070G>A INTRON1 Unknown significance rs771972761 This variant is a VUS because it does not have enough information. 763135 chr7:45615860:G>A ADCY1 NM_021116:c.639+1079G>A INTRON1 Unknown significance rs777757323 This variant is a VUS because it does not have enough information. 763136 chr7:45615880:G>A ADCY1 NM_021116:c.639+1099G>A INTRON1 Benign rs77239239 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 38 1322 0.0287 30 1006 0.0298 22 694 0.0317 162 1008 0.1607 104 978 0.1063 356 5008 0.0710863 763137 chr7:45615918:G>A ADCY1 NM_021116:c.639+1137G>A INTRON1 Unknown significance rs756184009 This variant is a VUS because it does not have enough information. 763138 chr7:45615921:TG>- ADCY1 NM_021116:c.639+1140_639+1141delTG INTRON1 Unknown significance rs556672185 This variant is a VUS because it does not have enough information. 6 1322 0.0045 0 1006 0 0 694 0 0 1008 0 0 978 0 6 5008 0.00119808 763139 chr7:45615942:CAGT>- ADCY1 NM_021116:c.639+1161_639+1164delCAGT INTRON1 Benign rs367978525 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 5 1322 0.0038 5 1006 0.005 0 694 0 7 1008 0.0069 47 978 0.0481 64 5008 0.0127796 763140 chr7:45615956:A>G ADCY1 NM_021116:c.639+1175A>G INTRON1 Benign rs4724419 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 1320 1322 0.9985 993 1006 0.9871 688 694 0.9914 1008 1008 1 978 978 1 4987 5008 0.995807 763141 chr7:45615968:A>G ADCY1 NM_021116:c.639+1187A>G INTRON1 Unknown significance rs541609251 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 763142 chr7:45615970:C>A ADCY1 NM_021116:c.639+1189C>A INTRON1 Unknown significance rs757581582 This variant is a VUS because it does not have enough information. 763143 chr7:45615979:G>A ADCY1 NM_021116:c.639+1198G>A INTRON1 Unknown significance rs374189075 This variant is a VUS because it does not have enough information. 763144 chr7:45616041:G>T ADCY1 NM_021116:c.639+1260G>T INTRON1 Unknown significance rs779252024 This variant is a VUS because it does not have enough information. 763145 chr7:45616075:C>T ADCY1 NM_021116:c.639+1294C>T INTRON1 Benign rs11979797 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 164 1322 0.1241 50 1006 0.0497 27 694 0.0389 0 1008 0 7 978 0.0072 248 5008 0.0495208 763146 chr7:45616107:A>G ADCY1 NM_021116:c.639+1326A>G INTRON1 Unknown significance rs763115041 This variant is a VUS because it does not have enough information. 763147 chr7:45616113:G>A ADCY1 NM_021116:c.639+1332G>A INTRON1 Benign rs78436178 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 2 1322 0.0015 9 1006 0.0089 79 694 0.1138 302 1008 0.2996 45 978 0.046 437 5008 0.0872604 763148 chr7:45616131:A>C ADCY1 NM_021116:c.639+1350A>C INTRON1 Benign rs11972954 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 26 1322 0.0197 0 1006 0 0 694 0 0 1008 0 0 978 0 26 5008 0.00519169 763149 chr7:45616187:G>A ADCY1 NM_021116:c.639+1406G>A INTRON1 Unknown significance rs562960145 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 3 1008 0.003 0 978 0 3 5008 0.000599042 763150 chr7:45616198:C>G ADCY1 NM_021116:c.639+1417C>G INTRON1 Unknown significance rs530409969 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681 763151 chr7:45616213:G>T ADCY1 NM_021116:c.639+1432G>T INTRON1 Unknown significance rs376098725 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361 763152 chr7:45616214:C>A ADCY1 NM_021116:c.639+1433C>A INTRON1 Unknown significance rs564404193 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 763153 chr7:45616226:C>T ADCY1 NM_021116:c.639+1445C>T INTRON1 Unknown significance rs528317772 This variant is a VUS because it does not have enough information. 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403 763154 chr7:45616241:C>T ADCY1 NM_021116:c.639+1460C>T INTRON1 Unknown significance rs780587291 This variant is a VUS because it does not have enough information. 763155 chr7:45616280:A>G ADCY1 NM_021116:c.639+1499A>G INTRON1 Benign rs58500623 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 12 1322 0.0091 0 1006 0 3 694 0.0043 0 1008 0 0 978 0 15 5008 0.00299521 763156 chr7:45616293:T>A ADCY1 NM_021116:c.639+1512T>A INTRON1 Unknown significance rs568216723 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681 763157 chr7:45616301:C>G ADCY1 NM_021116:c.639+1520C>G INTRON1 Unknown significance rs536762838 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 2 5008 0.000399361 763158 chr7:45616334:G>C ADCY1 NM_021116:c.639+1553G>C INTRON1 Unknown significance rs548664887 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 763159 chr7:45616336:C>- ADCY1 NM_021116:c.639+1555delC INTRON1 Unknown significance rs747452045 This variant is a VUS because it does not have enough information. 763160 chr7:45616352:C>T ADCY1 NM_021116:c.639+1571C>T INTRON1 Unknown significance rs542371643 This variant is a VUS because it does not have enough information. 763161 chr7:45616365:C>T ADCY1 NM_021116:c.639+1584C>T INTRON1 Unknown significance rs140090608 This variant is a VUS because it does not have enough information. 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403 763162 chr7:45616382:C>T ADCY1 NM_021116:c.639+1601C>T INTRON1 Unknown significance rs747663179 This variant is a VUS because it does not have enough information. 763163 chr7:45616478:C>T ADCY1 NM_021116:c.639+1697C>T INTRON1 Unknown significance rs563745525 This variant is a VUS because it does not have enough information. 763164 chr7:45616494:G>C ADCY1 NM_021116:c.639+1713G>C INTRON1 Unknown significance rs767923548 This variant is a VUS because it does not have enough information. 763165 chr7:45616504:G>C ADCY1 NM_021116:c.639+1723G>C INTRON1 Benign rs6977779 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 14 1322 0.0106 0 1006 0 0 694 0 0 1008 0 0 978 0 14 5008 0.00279553 763166 chr7:45616504:G>T ADCY1 NM_021116:c.639+1723G>T INTRON1 Unknown significance rs6977779 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 3 978 0.0031 3 5008 0.000599042 763167 chr7:45616509:G>A ADCY1 NM_021116:c.639+1728G>A INTRON1 Unknown significance rs750892273 This variant is a VUS because it does not have enough information. 763168 chr7:45616537:A>G ADCY1 NM_021116:c.639+1756A>G INTRON1 Benign rs75813508 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 63 1322 0.0477 19 1006 0.0189 10 694 0.0144 26 1008 0.0258 36 978 0.0368 154 5008 0.0307508 763169 chr7:45616541:T>G ADCY1 NM_021116:c.639+1760T>G INTRON1 Unknown significance rs765935242 This variant is a VUS because it does not have enough information. 763170 chr7:45616563:T>G ADCY1 NM_021116:c.639+1782T>G INTRON1 Unknown significance rs186754300 This variant is a VUS because it does not have enough information. 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403 763171 chr7:45616612:A>G ADCY1 NM_021116:c.639+1831A>G INTRON1 Unknown significance rs553153862 This variant is a VUS because it does not have enough information. 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361 763172 chr7:45616674:G>C ADCY1 NM_021116:c.639+1893G>C INTRON1 Unknown significance rs574658249 This variant is a VUS because it does not have enough information. 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361 763173 chr7:45616676:C>T ADCY1 NM_021116:c.639+1895C>T INTRON1 Unknown significance rs190117847 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 2 5008 0.000399361 763174 chr7:45616694:A>G ADCY1 NM_021116:c.639+1913A>G INTRON1 Benign rs150023156 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 14 1322 0.0106 0 1006 0 0 694 0 1 1008 0.001 0 978 0 15 5008 0.00299521 763175 chr7:45616736:G>T ADCY1 NM_021116:c.639+1955G>T INTRON1 Unknown significance rs574942411 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763176 chr7:45616761:T>C ADCY1 NM_021116:c.639+1980T>C INTRON1 Unknown significance rs762528898 This variant is a VUS because it does not have enough information. 763177 chr7:45616772:A>G ADCY1 NM_021116:c.639+1991A>G INTRON1 Unknown significance rs545775759 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763178 chr7:45616774:G>A ADCY1 NM_021116:c.639+1993G>A INTRON1 Unknown significance rs563887572 This variant is a VUS because it does not have enough information. 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763179 chr7:45616812:A>G ADCY1 NM_021116:c.639+2031A>G INTRON1 Unknown significance rs145343321 This variant is a VUS because it does not have enough information. 4 1322 0.003 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 5 5008 0.000998403 763180 chr7:45616861:A>G ADCY1 NM_021116:c.639+2080A>G INTRON1 Unknown significance rs753373655 This variant is a VUS because it does not have enough information. 763181 chr7:45616873:C>G ADCY1 NM_021116:c.639+2092C>G INTRON1 Unknown significance rs540125037 This variant is a VUS because it does not have enough information. 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361 763182 chr7:45616898:A>G ADCY1 NM_021116:c.639+2117A>G INTRON1 Unknown significance rs561883607 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681 763183 chr7:45616909:C>T ADCY1 NM_021116:c.639+2128C>T INTRON1 Unknown significance rs574109465 This variant is a VUS because it does not have enough information. 763184 chr7:45616935:T>C ADCY1 NM_021116:c.639+2154T>C INTRON1 Unknown significance rs770695831 This variant is a VUS because it does not have enough information. 763185 chr7:45616947:->G ADCY1 NM_021116:c.639+2166_639+2167insG INTRON1 Unknown significance rs34673212 This variant is a VUS because it does not have enough information. 763186 chr7:45616951:A>T ADCY1 NM_021116:c.639+2170A>T INTRON1 Unknown significance rs778626987 This variant is a VUS because it does not have enough information. 763187 chr7:45616955:A>G ADCY1 NM_021116:c.639+2174A>G INTRON1 Unknown significance rs529087120 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681 763188 chr7:45616966:C>T ADCY1 NM_021116:c.639+2185C>T INTRON1 Unknown significance rs371472241 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 4 1008 0.004 0 978 0 4 5008 0.000798722 763189 chr7:45616970:C>G ADCY1 NM_021116:c.639+2189C>G INTRON1 Unknown significance rs752495516 This variant is a VUS because it does not have enough information. 763190 chr7:45616999:A>G ADCY1 NM_021116:c.639+2218A>G INTRON1 Benign rs149228627 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 4 1322 0.003 28 1006 0.0278 5 694 0.0072 10 1008 0.0099 101 978 0.1033 148 5008 0.0295527 763191 chr7:45617009:C>T ADCY1 NM_021116:c.639+2228C>T INTRON1 Unknown significance rs530852227 This variant is a VUS because it does not have enough information. 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403 763192 chr7:45617015:A>G ADCY1 NM_021116:c.639+2234A>G INTRON1 Unknown significance rs552551538 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681 763193 chr7:45617059:T>C ADCY1 NM_021116:c.639+2278T>C INTRON1 Unknown significance rs570710669 This variant is a VUS because it does not have enough information. 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763194 chr7:45617060:C>T ADCY1 NM_021116:c.639+2279C>T INTRON1 Unknown significance rs777580844 This variant is a VUS because it does not have enough information. 763195 chr7:45617094:G>A ADCY1 NM_021116:c.639+2313G>A INTRON1 Unknown significance rs535601658 This variant is a VUS because it does not have enough information. 763196 chr7:45617109:C>T ADCY1 NM_021116:c.639+2328C>T INTRON1 Unknown significance rs369207439 This variant is a VUS because it does not have enough information. 763197 chr7:45617130:T>C ADCY1 NM_021116:c.639+2349T>C INTRON1 Benign rs535349622 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 8 1322 0.0061 0 1006 0 0 694 0 0 1008 0 0 978 0 8 5008 0.00159744 763198 chr7:45617131:C>T ADCY1 NM_021116:c.639+2350C>T INTRON1 Benign rs143386069 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 0 1322 0 0 1006 0 0 694 0 14 1008 0.0139 0 978 0 14 5008 0.00279553 763199 chr7:45617192:G>A ADCY1 NM_021116:c.639+2411G>A INTRON1 Unknown significance rs568342942 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681 763200 chr7:45617279:A>G ADCY1 NM_021116:c.639+2498A>G INTRON1 Unknown significance rs535648638 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 763201 chr7:45617293:C>T ADCY1 NM_021116:c.639+2512C>T INTRON1 Unknown significance rs556678018 This variant is a VUS because it does not have enough information. 2 1322 0.0015 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 3 5008 0.000599042 763202 chr7:45617319:C>G ADCY1 NM_021116:c.639+2538C>G INTRON1 Unknown significance rs769885334 This variant is a VUS because it does not have enough information. 763203 chr7:45617372:T>A ADCY1 NM_021116:c.639+2591T>A INTRON1 Unknown significance rs759466494 This variant is a VUS because it does not have enough information. 763204 chr7:45617383:T>G ADCY1 NM_021116:c.639+2602T>G INTRON1 Benign rs78338109 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 0 1322 0 1 1006 0.001 15 694 0.0216 125 1008 0.124 34 978 0.0348 175 5008 0.0349441 763205 chr7:45617405:C>T ADCY1 NM_021116:c.639+2624C>T INTRON1 Benign rs115342333 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 13 1322 0.0098 0 1006 0 0 694 0 0 1008 0 0 978 0 13 5008 0.00259585 763206 chr7:45617408:G>T ADCY1 NM_021116:c.639+2627G>T INTRON1 Unknown significance rs749336657 This variant is a VUS because it does not have enough information. 763207 chr7:45617422:G>A ADCY1 NM_021116:c.639+2641G>A INTRON1 Unknown significance rs557753945 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 763208 chr7:45617433:C>T ADCY1 NM_021116:c.639+2652C>T INTRON1 Benign rs115787895 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 11 1322 0.0083 0 1006 0 0 694 0 0 1008 0 0 978 0 11 5008 0.00219649 763209 chr7:45617472:G>A ADCY1 NM_021116:c.639+2691G>A INTRON1 Unknown significance rs768817045 This variant is a VUS because it does not have enough information. 763210 chr7:45617488:T>A ADCY1 NM_021116:c.639+2707T>A INTRON1 Unknown significance rs181405465 This variant is a VUS because it does not have enough information. 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403 763211 chr7:45617493:C>A ADCY1 NM_021116:c.639+2712C>A INTRON1 Unknown significance rs752707760 This variant is a VUS because it does not have enough information. 763212 chr7:45617513:C>T ADCY1 NM_021116:c.639+2732C>T INTRON1 Unknown significance rs774574445 This variant is a VUS because it does not have enough information. 763213 chr7:45617518:G>A ADCY1 NM_021116:c.639+2737G>A INTRON1 Benign rs185937564 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 7 1322 0.0053 0 1006 0 0 694 0 0 1008 0 0 978 0 7 5008 0.00139776 763214 chr7:45617536:T>A ADCY1 NM_021116:c.639+2755T>A INTRON1 Unknown significance rs760771734 This variant is a VUS because it does not have enough information. 763215 chr7:45617565:G>A ADCY1 NM_021116:c.639+2784G>A INTRON1 Unknown significance rs529150659 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681 763216 chr7:45617596:C>A ADCY1 NM_021116:c.639+2815C>A INTRON1 Unknown significance rs544412603 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681 763217 chr7:45617628:G>A ADCY1 NM_021116:c.639+2847G>A INTRON1 Benign rs79268889 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 0 1322 0 1 1006 0.001 15 694 0.0216 125 1008 0.124 34 978 0.0348 175 5008 0.0349441 763218 chr7:45617630:A>G ADCY1 NM_021116:c.639+2849A>G INTRON1 Unknown significance rs201513838 This variant is a VUS because it does not have enough information. 763219 chr7:45617640:C>G ADCY1 NM_021116:c.639+2859C>G INTRON1 Unknown significance rs531037916 This variant is a VUS because it does not have enough information. 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763220 chr7:45617661:C>G ADCY1 NM_021116:c.639+2880C>G INTRON1 Unknown significance rs552361512 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 0 978 0 0 5008 0 763221 chr7:45617698:C>T ADCY1 NM_021116:c.639+2917C>T INTRON1 Unknown significance rs146795025 This variant is a VUS because it does not have enough information. 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042 763222 chr7:45617722:C>T ADCY1 NM_021116:c.639+2941C>T INTRON1 Unknown significance rs528453192 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 763223 chr7:45617752:G>C ADCY1 NM_021116:c.639+2971G>C INTRON1 Unknown significance rs772437596 This variant is a VUS because it does not have enough information. 763224 chr7:45617815:C>T ADCY1 NM_021116:c.639+3034C>T INTRON1 Unknown significance rs773874157 This variant is a VUS because it does not have enough information. 763225 chr7:45617845:C>T ADCY1 NM_021116:c.639+3064C>T INTRON1 Unknown significance rs546935477 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763226 chr7:45617859:C>A ADCY1 NM_021116:c.639+3078C>A INTRON1 Unknown significance rs761311232 This variant is a VUS because it does not have enough information. 763227 chr7:45617862:T>G ADCY1 NM_021116:c.639+3081T>G INTRON1 Unknown significance rs568403788 This variant is a VUS because it does not have enough information. 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763228 chr7:45617881:C>A ADCY1 NM_021116:c.639+3100C>A INTRON1 Unknown significance rs535708478 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681 763229 chr7:45617893:G>A ADCY1 NM_021116:c.639+3112G>A INTRON1 Unknown significance rs140481106 This variant is a VUS because it does not have enough information. 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763230 chr7:45617901:->G ADCY1 NM_021116:c.639+3120_639+3121insG INTRON1 Benign rs565184011 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 11 1322 0.0083 1 1006 0.001 1 694 0.0014 0 1008 0 0 978 0 13 5008 0.00259585 763231 chr7:45617901:G>A ADCY1 NM_021116:c.639+3120G>A INTRON1 Unknown significance rs77226271 This variant is a VUS because it does not have enough information. 763232 chr7:45617901:G>T ADCY1 NM_021116:c.639+3120G>T INTRON1 Unknown significance rs77226271 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 3 978 0.0031 3 5008 0.000599042 763233 chr7:45617902:G>C ADCY1 NM_021116:c.639+3121G>C INTRON1 Unknown significance rs766959182 This variant is a VUS because it does not have enough information. 763234 chr7:45617937:A>G ADCY1 NM_021116:c.639+3156A>G INTRON1 Unknown significance rs539532212 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763235 chr7:45617981:A>G ADCY1 NM_021116:c.639+3200A>G INTRON1 Benign rs10807926 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 461 1322 0.3487 448 1006 0.4453 264 694 0.3804 514 1008 0.5099 499 978 0.5102 2186 5008 0.436502 763236 chr7:45617997:C>A ADCY1 NM_021116:c.639+3216C>A INTRON1 Unknown significance rs572826798 This variant is a VUS because it does not have enough information. 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403 763237 chr7:45618001:C>G ADCY1 NM_021116:c.639+3220C>G INTRON1 Unknown significance rs759076039 This variant is a VUS because it does not have enough information. 763238 chr7:45618005:C>T ADCY1 NM_021116:c.639+3224C>T INTRON1 Benign rs10951823 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 473 1322 0.3578 478 1006 0.4751 286 694 0.4121 672 1008 0.6667 603 978 0.6166 2512 5008 0.501597 763239 chr7:45618083:G>C ADCY1 NM_021116:c.639+3302G>C INTRON1 Benign rs10951824 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 177 1322 0.1339 351 1006 0.3489 220 694 0.317 474 1008 0.4702 355 978 0.363 1577 5008 0.314896 763240 chr7:45618116:T>C ADCY1 NM_021116:c.639+3335T>C INTRON1 Unknown significance rs573994197 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763241 chr7:45618151:G>A ADCY1 NM_021116:c.639+3370G>A INTRON1 Unknown significance rs544472918 This variant is a VUS because it does not have enough information. 0 1322 0 2 1006 0.002 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361 763242 chr7:45618182:T>C ADCY1 NM_021116:c.639+3401T>C INTRON1 Unknown significance rs371761404 This variant is a VUS because it does not have enough information. 763243 chr7:45618230:G>T ADCY1 NM_021116:c.639+3449G>T INTRON1 Unknown significance rs562725069 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681 763244 chr7:45618273:G>T ADCY1 NM_021116:c.639+3492G>T INTRON1 Unknown significance rs145709267 This variant is a VUS because it does not have enough information. 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763245 chr7:45618288:C>A ADCY1 NM_021116:c.639+3507C>A INTRON1 Unknown significance rs138278818 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763246 chr7:45618303:C>T ADCY1 NM_021116:c.639+3522C>T INTRON1 Unknown significance rs568106690 This variant is a VUS because it does not have enough information. 763247 chr7:45618304:G>A ADCY1 NM_021116:c.639+3523G>A INTRON1 Unknown significance rs564419630 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 763248 chr7:45618320:C>T ADCY1 NM_021116:c.639+3539C>T INTRON1 Unknown significance rs548347333 This variant is a VUS because it does not have enough information. 763249 chr7:45618347:G>A ADCY1 NM_021116:c.639+3566G>A INTRON1 Unknown significance rs528526674 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 3 1008 0.003 0 978 0 3 5008 0.000599042 763250 chr7:45618363:A>G ADCY1 NM_021116:c.639+3582A>G INTRON1 Unknown significance rs546596897 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763251 chr7:45618378:C>A ADCY1 NM_021116:c.639+3597C>A INTRON1 Unknown significance rs751334807 This variant is a VUS because it does not have enough information. 763252 chr7:45618390:T>A ADCY1 NM_021116:c.639+3609T>A INTRON1 Unknown significance rs757226648 This variant is a VUS because it does not have enough information. 763254 chr7:45618396:T>G ADCY1 NM_021116:c.639+3615T>G INTRON1 Unknown significance rs561698330 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 763253 chr7:45618396:TCC>- ADCY1 NM_021116:c.639+3615_639+3617delTCC INTRON1 Unknown significance rs796924130 This variant is a VUS because it does not have enough information. 763255 chr7:45618407:C>G ADCY1 NM_021116:c.639+3626C>G INTRON1 Unknown significance rs781092341 This variant is a VUS because it does not have enough information. 763256 chr7:45618416:T>C ADCY1 NM_021116:c.639+3635T>C INTRON1 Unknown significance rs529562852 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763257 chr7:45618436:C>T ADCY1 NM_021116:c.639+3655C>T INTRON1 Unknown significance rs190789844 This variant is a VUS because it does not have enough information. 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403 763258 chr7:45618439:C>G ADCY1 NM_021116:c.639+3658C>G INTRON1 Benign rs4529350 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 213 1322 0.1611 78 1006 0.0775 34 694 0.049 10 1008 0.0099 108 978 0.1104 443 5008 0.0884585 763259 chr7:45618442:T>G ADCY1 NM_021116:c.639+3661T>G INTRON1 Unknown significance rs569788915 This variant is a VUS because it does not have enough information. 763260 chr7:45618458:C>T ADCY1 NM_021116:c.639+3677C>T INTRON1 Unknown significance rs780489296 This variant is a VUS because it does not have enough information. 763261 chr7:45618481:->T ADCY1 NM_021116:c.639+3700_639+3701insT INTRON1 Unknown significance rs35406812 This variant is a VUS because it does not have enough information. 763262 chr7:45618492:A>G ADCY1 NM_021116:c.639+3711A>G INTRON1 Benign rs141736735 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 0 1322 0 0 1006 0 0 694 0 15 1008 0.0149 2 978 0.002 17 5008 0.00339457 763263 chr7:45618513:T>C ADCY1 NM_021116:c.639+3732T>C INTRON1 Benign rs78344730 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 0 1322 0 1 1006 0.001 15 694 0.0216 125 1008 0.124 34 978 0.0348 175 5008 0.0349441 763264 chr7:45618531:T>G ADCY1 NM_021116:c.639+3750T>G INTRON1 Unknown significance rs547084374 This variant is a VUS because it does not have enough information. 763265 chr7:45618538:C>T ADCY1 NM_021116:c.639+3757C>T INTRON1 Unknown significance rs748349744 This variant is a VUS because it does not have enough information. 763266 chr7:45618558:G>A ADCY1 NM_021116:c.639+3777G>A INTRON1 Unknown significance rs772158709 This variant is a VUS because it does not have enough information. 763267 chr7:45618570:T>G ADCY1 NM_021116:c.639+3789T>G INTRON1 Benign rs184169017 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 0 1322 0 0 1006 0 0 694 0 7 1008 0.0069 0 978 0 7 5008 0.00139776 763268 chr7:45618622:C>T ADCY1 NM_021116:c.639+3841C>T INTRON1 Benign rs74698704 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 9 1322 0.0068 29 1006 0.0288 7 694 0.0101 37 1008 0.0367 67 978 0.0685 149 5008 0.0297524 763269 chr7:45618631:G>A ADCY1 NM_021116:c.639+3850G>A INTRON1 Benign rs187561557 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 0 1322 0 0 1006 0 0 694 0 6 1008 0.006 0 978 0 6 5008 0.00119808 763270 chr7:45618640:C>G ADCY1 NM_021116:c.639+3859C>G INTRON1 Unknown significance rs150153106 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763271 chr7:45618671:C>T ADCY1 NM_021116:c.639+3890C>T INTRON1 Unknown significance rs59442380 This variant is a VUS because it does not have enough information. 763272 chr7:45618690:C>T ADCY1 NM_021116:c.639+3909C>T INTRON1 Unknown significance rs538153526 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681 763273 chr7:45618732:C>T ADCY1 NM_021116:c.639+3951C>T INTRON1 Benign rs79515181 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 9 1322 0.0068 29 1006 0.0288 7 694 0.0101 37 1008 0.0367 67 978 0.0685 149 5008 0.0297524 763274 chr7:45618737:A>C ADCY1 NM_021116:c.639+3956A>C INTRON1 Unknown significance rs577814302 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 763275 chr7:45618746:G>T ADCY1 NM_021116:c.639+3965G>T INTRON1 Unknown significance rs771626361 This variant is a VUS because it does not have enough information. 763276 chr7:45618751:A>G ADCY1 NM_021116:c.639+3970A>G INTRON1 Unknown significance rs569784709 This variant is a VUS because it does not have enough information. 763277 chr7:45618786:T>C ADCY1 NM_021116:c.639+4005T>C INTRON1 Unknown significance rs138584557 This variant is a VUS because it does not have enough information. 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042 763278 chr7:45618788:G>A ADCY1 NM_021116:c.639+4007G>A INTRON1 Benign rs76835720 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 63 1322 0.0477 19 1006 0.0189 10 694 0.0144 26 1008 0.0258 36 978 0.0368 154 5008 0.0307508 763279 chr7:45618802:C>T ADCY1 NM_021116:c.639+4021C>T INTRON1 Unknown significance rs149333919 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763280 chr7:45618823:A>G ADCY1 NM_021116:c.639+4042A>G INTRON1 Unknown significance rs540300058 This variant is a VUS because it does not have enough information. 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763281 chr7:45618826:C>T ADCY1 NM_021116:c.639+4045C>T INTRON1 Unknown significance rs561759734 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 763282 chr7:45618842:G>A ADCY1 NM_021116:c.639+4061G>A INTRON1 Unknown significance rs191203239 This variant is a VUS because it does not have enough information. 0 1322 0 3 1006 0.003 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042 763283 chr7:45618867:A>C ADCY1 NM_021116:c.639+4086A>C INTRON1 Unknown significance rs551288572 This variant is a VUS because it does not have enough information. 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403 763284 chr7:45618868:C>G ADCY1 NM_021116:c.639+4087C>G INTRON1 Benign rs76323096 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 18 1322 0.0136 0 1006 0 0 694 0 0 1008 0 0 978 0 18 5008 0.00359425 763285 chr7:45618882:G>A ADCY1 NM_021116:c.639+4101G>A INTRON1 Unknown significance rs111244229 This variant is a VUS because it does not have enough information. 763286 chr7:45618958:G>T ADCY1 NM_021116:c.639+4177G>T INTRON1 Unknown significance rs533617804 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 763287 chr7:45618962:C>T ADCY1 NM_021116:c.639+4181C>T INTRON1 Unknown significance rs551694790 This variant is a VUS because it does not have enough information. 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763288 chr7:45618986:C>T ADCY1 NM_021116:c.639+4205C>T INTRON1 Unknown significance rs567009174 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 763289 chr7:45618987:G>C ADCY1 NM_021116:c.639+4206G>C INTRON1 Unknown significance rs527405220 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 2 5008 0.000399361 763290 chr7:45619019:C>G ADCY1 NM_021116:c.639+4238C>G INTRON1 Unknown significance rs549066278 This variant is a VUS because it does not have enough information. 763291 chr7:45619019:C>T ADCY1 NM_021116:c.639+4238C>T INTRON1 Unknown significance rs549066278 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681 763292 chr7:45619031:T>C ADCY1 NM_021116:c.639+4250T>C INTRON1 Benign rs867582 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 457 1322 0.3457 448 1006 0.4453 264 694 0.3804 510 1008 0.506 499 978 0.5102 2178 5008 0.434904 763293 chr7:45619072:C>A ADCY1 NM_021116:c.639+4291C>A INTRON1 Unknown significance rs537837202 This variant is a VUS because it does not have enough information. 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042 763294 chr7:45619083:C>T ADCY1 NM_021116:c.639+4302C>T INTRON1 Unknown significance rs556461975 This variant is a VUS because it does not have enough information. 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763295 chr7:45619111:C>T ADCY1 NM_021116:c.639+4330C>T INTRON1 Unknown significance rs368508495 This variant is a VUS because it does not have enough information. 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763296 chr7:45619116:A>G ADCY1 NM_021116:c.639+4335A>G INTRON1 Unknown significance rs182576149 This variant is a VUS because it does not have enough information. 0 1322 0 2 1006 0.002 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361 763297 chr7:45619119:T>C ADCY1 NM_021116:c.639+4338T>C INTRON1 Benign rs2877339 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 490 1322 0.3707 478 1006 0.4751 286 694 0.4121 672 1008 0.6667 603 978 0.6166 2529 5008 0.504992 763298 chr7:45619169:C>A ADCY1 NM_021116:c.639+4388C>A INTRON1 Unknown significance rs372822877 This variant is a VUS because it does not have enough information. 763299 chr7:45619200:C>T ADCY1 NM_021116:c.639+4419C>T INTRON1 Unknown significance rs187003728 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763300 chr7:45619203:C>T ADCY1 NM_021116:c.639+4422C>T INTRON1 Unknown significance rs540358183 This variant is a VUS because it does not have enough information. 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763301 chr7:45619224:C>T ADCY1 NM_021116:c.639+4443C>T INTRON1 Unknown significance rs537338513 This variant is a VUS because it does not have enough information.