762745 chr7:45613857:G>A ADCY1 Unknown significance rs369786422 This variant is a VUS because it does not have enough information. 762746 chr7:45613955:C>G ADCY1 Unknown significance rs561544199 This variant is a VUS because it does not have enough information. 0 1322 0 4 1006 0.004 2 694 0.0029 0 1008 0 0 978 0 6 5008 0.00119808 762747 chr7:45614145:G>- ADCY1 NM_021116:c.3delG EXON1 Unknown significance rs567962651 4 1322 0.003 0 1006 0 0 694 0 1 1008 0.001 6 978 0.0061 11 5008 0.00219649 762748 chr7:45614242:C>G ADCY1 NM_021116:p.Arg34Gly NM_021116:c.100C>G EXON1 Benign rs760606743 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 0.691 N 0.389 T 0.0 B 0.188742 U 1 N;N -0.384 N 1 4 0.25 0 0 0 0 12 0 0 0 0 0 28 0 0 4 0 0 156 0 1 204 0.00490196 762749 chr7:45614280:G>A ADCY1 NM_021116:p.Glu46Glu NM_021116:c.138G>A EXON1 Unknown significance rs764099850 This variant is a VUS because it does not have enough information. 0 32 0 0 22 0 0 50 0 0 0 0 1 402 0.00248756 0 26 0 0 1416 0 1 1948 0.000513347 762750 chr7:45614307:G>A ADCY1 NM_021116:p.Arg55Arg NM_021116:c.165G>A EXON1 Unknown significance rs753933695 This variant is a VUS because it does not have enough information. 0 56 0 0 28 0 0 60 0 0 2 0 1 534 0.00187266 0 34 0 0 2008 0 1 2722 0.000367377 762751 chr7:45614312:A>G ADCY1 NM_021116:p.Glu57Gly NM_021116:c.170A>G EXON1 Unknown significance rs552168629 This variant is a VUS because it does not have enough information. 0.092 N 0.059 T 0.996 D 0 D 0.999454 D;D 2.81 C 762752 chr7:45614346:C>T ADCY1 NM_021116:p.Leu68Leu NM_021116:c.204C>T EXON1 Unknown significance rs531991756 This variant is a VUS because it does not have enough information. 0 1322 0 2 1006 0.002 1 694 0.0014 0 1008 0 0 978 0 3 5008 0.000599042 762753 chr7:45614359:G>A ADCY1 NM_021116:p.Gly73Ser NM_021116:c.217G>A EXON1 Likely benign rs544024276 Pathogenicity is based on prediction data only. 2 out of 6 predictions were pathogenic. 0.875 N 0.494 T 0.003 B 0.028641 N 0.987602 D;D 3.96 C 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 762755 chr7:45614376:C>A ADCY1 NM_021116:p.Ala78Ala NM_021116:c.234C>A EXON1 Benign rs74641956 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 0 276 0 0 108 0 4 256 0.015625 0 366 0 0 2540 0 0 84 0 0 4932 0 4 8562 0.000467181 762754 chr7:45614376:C>G ADCY1 NM_021116:p.Ala78Ala NM_021116:c.234C>G EXON1 Benign rs74641956 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 1 1322 0.0008 18 1006 0.0179 6 694 0.0086 0 1008 0 0 978 0 25 5008 0.00499201 4 276 0.0144928 4 108 0.037037 0 256 0 20 366 0.0546448 240 2540 0.0944882 1 84 0.0119048 19 4932 0.00385239 288 8562 0.033637 762756 chr7:45614388:C>A ADCY1 NM_021116:p.Gly82Gly NM_021116:c.246C>A EXON1 Unknown significance rs758855790 This variant is a VUS because it does not have enough information. 1 930 0.00107527 0 578 0 0 978 0 0 550 0 0 6586 0 0 166 0 0 7046 0 1 16834 0.0000594036 762757 chr7:45614390:C>T ADCY1 NM_021116:p.Ala83Val NM_021116:c.248C>T EXON1 Benign rs375141353 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 0.783 N 0.317 T 0.715 P 0.324801 N 1 D;N 0.505 C 0 1322 0 0 1006 0 0 694 0 0 1008 0 8 978 0.0082 8 5008 0.00159744 0 1134 0 1 754 0.00132626 0 1228 0 0 820 0 0 8144 0 1 190 0.00526316 115 7668 0.0149974 117 19938 0.00586819 762758 chr7:45614391:G>T ADCY1 NM_021116:p.Ala83Ala NM_021116:c.249G>T EXON1 Unknown significance rs747493330 This variant is a VUS because it does not have enough information. 0 1340 0 0 932 0 1 1424 0.000702247 0 1012 0 0 9664 0 0 200 0 0 8134 0 1 22706 0.0000440412 762759 chr7:45614392:C>T ADCY1 NM_021116:p.Pro84Ser NM_021116:c.250C>T EXON1 Unknown significance rs79229229 This variant is a VUS because it does not have enough information. 0.783 N 0.436 T 0.759 P 0.000011 D 0.852915 D;D 3.69 C 762760 chr7:45614400:C>G ADCY1 NM_021116:p.Pro86Pro NM_021116:c.258C>G EXON1 Benign rs200597993 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 1 1322 0.0008 1 1006 0.001 2 694 0.0029 0 1008 0 1 978 0.001 5 5008 0.000998403 2 2838 0.000704722 1 3068 0.000325945 0 3356 0 0 1930 0 40 22654 0.00176569 0 336 0 105 10216 0.010278 148 44398 0.00333348 762761 chr7:45614400:C>T ADCY1 NM_021116:p.Pro86Pro NM_021116:c.258C>T EXON1 Unknown significance rs200597993 This variant is a VUS because it does not have enough information. 0 2838 0 0 3068 0 0 3356 0 0 1930 0 1 22654 0.0000441423 1 336 0.00297619 0 10216 0 2 44398 0.0000450471 762762 chr7:45614401:G>C ADCY1 NM_021116:p.Ala87Pro NM_021116:c.259G>C EXON1 Unknown significance rs748845827 This variant is a VUS because it does not have enough information. 0.874 N 0.142 T 0.574 P 0.00026 D 0.703355 D;D 2.8 C 0 2956 0 0 3310 0 0 3524 0 0 1956 0 1 24142 0.0000414216 0 346 0 0 10406 0 1 46640 0.0000214408 762763 chr7:45614405:C>T ADCY1 NM_021116:p.Pro88Leu NM_021116:c.263C>T EXON1 Likely benign rs770682134 Pathogenicity is based on prediction data only. 2 out of 6 predictions were pathogenic. -0.068 N 0.662 T 0.0 B 0.007712 N 0.986981 D;D 2.8 C 0 3980 0 2 5362 0.000372995 0 4798 0 0 2816 0 0 33858 0 0 452 0 0 11588 0 2 62854 0.0000318198 762764 chr7:45614407:G>A ADCY1 NM_021116:p.Gly89Ser NM_021116:c.265G>A EXON1 Unknown significance rs79204521 This variant is a VUS because it does not have enough information. 0.874 N 0.424 T 0.014 B 0.000142 D 1 D;N 2.69 C 762765 chr7:45614410:C>G ADCY1 NM_021116:p.Leu90Val NM_021116:c.268C>G EXON1 Unknown significance rs774107345 This variant is a VUS because it does not have enough information. 0.792 N 0.25 T 0.006 B 0.000117 D 1 D;N 3.69 C 0 5234 0 0 7780 0 0 6164 0 0 3810 0 1 44284 0.0000225815 0 570 0 0 12858 0 1 80700 0.0000123916 762766 chr7:45614414:C>T ADCY1 NM_021116:p.Ala91Val NM_021116:c.272C>T EXON1 Unknown significance rs77566296 This variant is a VUS because it does not have enough information. 0.792 N 0.64 T 0.501 P 0.00001 D 0.962163 D;D 2.8 C 762767 chr7:45614417:A>G ADCY1 NM_021116:p.Lys92Arg NM_021116:c.275A>G EXON1 Likely benign rs745641221 Pathogenicity is based on prediction data only. 2 out of 6 predictions were pathogenic. 0.097 N 0.486 T 0.002 B 0.000008 N 0.998817 D;D 2.53 C 0 6360 0 0 9694 0 0 7348 0 0 4790 0 0 52796 0 1 684 0.00146199 0 14118 0 1 95790 0.0000104395 762768 chr7:45614419:G>T ADCY1 NM_021116:p.Gly93Cys NM_021116:c.277G>T EXON1 Unknown significance rs771838265 This variant is a VUS because it does not have enough information. 0.884 N 0.163 T 1.0 D 0 D 0.999989 D;D 3.69 C 0 6546 0 0 9984 0 0 7514 0 0 4952 0 1 54064 0.0000184966 0 700 0 0 14356 0 1 98116 0.000010192 762769 chr7:45614430:G>A ADCY1 NM_021116:p.Pro96Pro NM_021116:c.288G>A EXON1 Unknown significance rs775165471 This variant is a VUS because it does not have enough information. 0 7452 0 0 10840 0 0 8102 0 0 5688 0 1 58884 0.0000169825 0 776 0 0 15454 0 1 107196 0.00000932871 762770 chr7:45614439:C>T ADCY1 NM_021116:p.Cys99Cys NM_021116:c.297C>T EXON1 Unknown significance rs776113547 This variant is a VUS because it does not have enough information. 0 7900 0 0 11036 0 0 8236 0 0 6046 0 1 60458 0.0000165404 0 792 0 0 15888 0 1 110356 0.00000906158 762771 chr7:45614440:G>A ADCY1 NM_021116:p.Val100Ile NM_021116:c.298G>A EXON1 Likely benign rs764052766 Pathogenicity is based on prediction data only. 2 out of 6 predictions were pathogenic. 0.045 N 0.83 T 0.003 B 0.002557 N 1 D;N 1.58 C 0 7950 0 0 11056 0 0 8248 0 0 6086 0 0 60648 0 0 798 0 1 15930 0.0000627746 1 110716 0.00000903212 762772 chr7:45614440:G>C ADCY1 NM_021116:p.Val100Leu NM_021116:c.298G>C EXON1 Likely benign rs764052766 Pathogenicity is based on prediction data only. 2 out of 6 predictions were pathogenic. 0.045 N 0.47 T 0.079 B 0.002557 N 1 D;N 1.58 C 0 7950 0 0 11056 0 0 8248 0 0 6086 0 1 60648 0.0000164886 0 798 0 0 15930 0 1 110716 0.00000903212 762773 chr7:45614442:C>T ADCY1 NM_021116:p.Val100Val NM_021116:c.300C>T EXON1 Unknown significance rs761931194 This variant is a VUS because it does not have enough information. 0 8038 0 0 11084 0 0 8266 0 0 6142 0 1 60856 0.0000164322 0 804 0 1 15974 0.0000626017 2 111164 0.0000179914 762774 chr7:45614454:G>A ADCY1 NM_021116:p.Ala104Ala NM_021116:c.312G>A EXON1 Unknown significance rs765365053 This variant is a VUS because it does not have enough information. 0 8236 0 0 11182 0 0 8306 0 0 6318 0 1 61504 0.0000162591 0 824 0 0 16170 0 1 112540 0.00000888573 762775 chr7:45614461:G>C ADCY1 NM_021116:p.Val107Leu NM_021116:c.319G>C EXON1 Unknown significance rs200378809 This variant is a VUS because it does not have enough information. 0.884 N 0.08 T 0.002 B 0.000055 D 0.988785 D;D 2.47 C 0 8322 0 0 11214 0 0 8316 0 1 6394 0.000156397 0 61686 0 0 836 0 0 16226 0 1 112994 0.00000885003 762776 chr7:45614461:G>T ADCY1 NM_021116:p.Val107Leu NM_021116:c.319G>T EXON1 Unknown significance rs200378809 This variant is a VUS because it does not have enough information. 0.884 N 0.08 T 0.002 B 0.000055 D 0.989214 D;D 2.47 C 0 8322 0 0 11214 0 2 8316 0.0002405 0 6394 0 0 61686 0 0 836 0 0 16226 0 2 112994 0.0000177001 762777 chr7:45614472:CGT>- ADCY1 NM_021116:c.330_332delCGT EXON1 Unknown significance rs761370974 This variant is a VUS because it does not have enough information. 762778 chr7:45614482:C>T ADCY1 NM_021116:p.Leu114Leu NM_021116:c.340C>T EXON1 Unknown significance rs766716634 This variant is a VUS because it does not have enough information. 0 8392 0 0 11258 0 0 8346 0 0 6450 0 0 61860 0 0 832 0 1 16280 0.0000614251 1 113418 0.00000881694 762779 chr7:45614499:G>A ADCY1 NM_021116:p.Leu119Leu NM_021116:c.357G>A EXON1 Unknown significance rs752002367 This variant is a VUS because it does not have enough information. 0 8442 0 0 11272 0 0 8342 0 0 6456 0 1 61946 0.0000161431 0 838 0 0 16274 0 1 113570 0.00000880514 762780 chr7:45614508:C>T ADCY1 NM_021116:p.Val122Val NM_021116:c.366C>T EXON1 Unknown significance rs755508070 This variant is a VUS because it does not have enough information. 0 8486 0 0 11268 0 0 8332 0 0 6442 0 0 61962 0 0 842 0 1 16274 0.0000614477 1 113606 0.00000880235 762781 chr7:45614533:C>T ADCY1 NM_021116:p.Leu131Phe NM_021116:c.391C>T EXON1 Unknown significance rs781776242 This variant is a VUS because it does not have enough information. 0.792 N 0.3 T 0.0 B 0.000013 D 0.886263 D;D 2.55 C 0 8490 0 0 11234 0 0 8328 0 0 6416 0 0 61802 0 0 842 0 1 16240 0.0000615764 1 113352 0.00000882208 762782 chr7:45614535:C>G ADCY1 NM_021116:p.Leu131Leu NM_021116:c.393C>G EXON1 Unknown significance rs753381717 This variant is a VUS because it does not have enough information. 0 8480 0 0 11234 0 0 8328 0 0 6412 0 0 61774 0 0 842 0 2 16232 0.000123213 2 113302 0.0000176519 762783 chr7:45614544:G>T ADCY1 NM_021116:p.Ala134Ala NM_021116:c.402G>T EXON1 Unknown significance rs756854830 This variant is a VUS because it does not have enough information. 0 8356 0 0 11202 0 0 8290 0 0 6364 0 0 61458 0 0 836 0 1 16196 0.0000617436 1 112702 0.00000887296 762784 chr7:45614550:C>T ADCY1 NM_021116:p.Leu136Leu NM_021116:c.408C>T EXON1 Unknown significance rs778295490 This variant is a VUS because it does not have enough information. 0 8332 0 1 11178 0.0000894614 0 8272 0 0 6366 0 0 61312 0 0 834 0 0 16182 0 1 112476 0.00000889079 762785 chr7:45614551:->CCCTTACA ADCY1 NM_021116:c.409_410insCCCTTACA EXON1 Unknown significance rs767679562 This variant is a VUS because it does not have enough information. 0 8332 0 0 11178 0 0 8272 0 0 6366 0 1 61312 0.00001631 0 834 0 0 16182 0 1 112476 0.00000889079 762786 chr7:45614553:->TAATCATCCAAATGGGAGTGGGTGGT ADCY1 NM_021116:c.411_412insTAATCATCCAAATGGGAGTGGGTGGT EXON1 Unknown significance rs750467665 This variant is a VUS because it does not have enough information. 762787 chr7:45614555:->A ADCY1 NM_021116:c.413_414insA EXON1 Unknown significance rs761016108 This variant is a VUS because it does not have enough information. 0 8242 0 0 11146 0 0 8250 0 0 6340 0 1 60870 0.0000164285 0 830 0 0 16162 0 1 111840 0.00000894134 762788 chr7:45614556:T>C ADCY1 NM_021116:p.Cys138Cys NM_021116:c.414T>C EXON1 Unknown significance rs745471312 This variant is a VUS because it does not have enough information. 0 8208 0 0 11128 0 0 8240 0 0 6334 0 1 60674 0.0000164815 0 828 0 0 16148 0 1 111560 0.00000896379 762789 chr7:45614562:C>G ADCY1 NM_021116:p.Phe140Leu NM_021116:c.420C>G EXON1 Likely benign rs771648046 Pathogenicity is based on prediction data only. 1 out of 6 predictions were pathogenic. -0.061 N 1.0 T 0.006 B 0.000006 N 0.983344 D;D -4.67 N 1 8008 0.000124875 0 11078 0 0 8142 0 0 6304 0 0 59560 0 0 812 0 0 16112 0 1 110016 0.00000908959 762790 chr7:45614563:G>T ADCY1 NM_021116:p.Ala141Ser NM_021116:c.421G>T EXON1 Unknown significance rs779862034 This variant is a VUS because it does not have enough information. 0.884 N 0.524 T 0.014 B 0.000041 D 1 D;N 1.46 C 0 7962 0 0 11082 0 0 8130 0 0 6292 0 1 59334 0.0000168537 0 812 0 0 16094 0 1 109706 0.00000911527 762791 chr7:45614565:G>C ADCY1 NM_021116:p.Ala141Ala NM_021116:c.423G>C EXON1 Unknown significance rs746848171 This variant is a VUS because it does not have enough information. 0 7972 0 0 11066 0 0 8130 0 0 6294 0 6 59344 0.000101105 0 812 0 3 16106 0.000186266 9 109724 0.000082024 762792 chr7:45614565:G>T ADCY1 NM_021116:p.Ala141Ala NM_021116:c.423G>T EXON1 Unknown significance rs746848171 This variant is a VUS because it does not have enough information. 0 7972 0 0 11066 0 0 8130 0 0 6294 0 1 59344 0.0000168509 0 812 0 0 16106 0 1 109724 0.00000911378 762793 chr7:45614571:C>G ADCY1 NM_021116:p.Gly143Gly NM_021116:c.429C>G EXON1 Unknown significance rs764921404 This variant is a VUS because it does not have enough information. 762794 chr7:45614576:C>T ADCY1 NM_021116:p.Pro145Leu NM_021116:c.434C>T EXON1 Unknown significance rs776609542 This variant is a VUS because it does not have enough information. 0.792 N 0.026 D 0.137 B 0.00339 N 0.997957 D;D 2.84 C 0 7702 0 0 10956 0 0 8018 0 0 6240 0 2 57924 0.000034528 0 794 0 0 16058 0 2 107692 0.0000185715 762795 chr7:45614582:G>A ADCY1 NM_021116:p.Arg147Gln NM_021116:c.440G>A EXON1 Likely benign rs761877943 Pathogenicity is based on prediction data only. 2 out of 5 predictions were pathogenic. 0.884 N 0.593 T 0.178 B 0.92601 U 0.99998 D;N 2.84 C 0 7624 0 0 10932 0 0 7988 0 0 6218 0 0 57626 0 0 794 0 1 16060 0.0000622665 1 107242 0.0000093247 762796 chr7:45614582:G>C ADCY1 NM_021116:p.Arg147Pro NM_021116:c.440G>C EXON1 Likely benign rs761877943 Pathogenicity is based on prediction data only. 2 out of 5 predictions were pathogenic. 0.884 N 0.309 T 0.165 B 0.92601 U 0.999984 D;N 2.84 C 0 7624 0 0 10932 0 1 7988 0.000125188 0 6218 0 0 57626 0 0 794 0 0 16060 0 1 107242 0.0000093247 762797 chr7:45614595:G>C ADCY1 NM_021116:p.Gly151Gly NM_021116:c.453G>C EXON1 Unknown significance rs773187376 This variant is a VUS because it does not have enough information. 0 7590 0 0 10888 0 0 7928 0 0 6162 0 0 57274 0 0 784 0 1 16056 0.000062282 1 106682 0.00000937365 762798 chr7:45614603:G>T ADCY1 NM_021116:p.Gly154Val NM_021116:c.461G>T EXON1 Likely benign rs763194212 Pathogenicity is based on prediction data only. 0 out of 6 predictions were pathogenic. -0.976 N 0.354 T 0.0 B 0.169948 N 0.999999 N;N -0.53 N 0 7632 0 0 10866 0 2 7930 0.000252207 0 6168 0 0 57376 0 0 780 0 0 16048 0 2 106800 0.0000187266 762799 chr7:45614604:G>A ADCY1 NM_021116:p.Gly154Gly NM_021116:c.462G>A EXON1 Unknown significance rs766548504 This variant is a VUS because it does not have enough information. 0 7702 0 0 10898 0 0 7956 0 0 6178 0 3 57516 0.0000521594 0 790 0 0 16066 0 3 107106 0.0000280096 762800 chr7:45614605:G>A ADCY1 NM_021116:p.Gly155Arg NM_021116:c.463G>A EXON1 Likely benign rs751947495 Pathogenicity is based on prediction data only. 1 out of 6 predictions were pathogenic. 0.884 N 0.543 T 0.0 B 0.001985 N 0.999974 N;N 2.7 C 0 7704 0 0 10900 0 0 7948 0 0 6162 0 1 57510 0.0000173883 0 790 0 0 16070 0 1 107084 0.00000933846 762801 chr7:45614636:A>C ADCY1 NM_021116:p.Gln165Pro NM_021116:c.494A>C EXON1 Unknown significance rs760033357 This variant is a VUS because it does not have enough information. 1.011 C 0.266 T 0.002 B 0 D 0.999975 D;D 3.7 C 0 8412 0 0 11024 0 0 8156 0 0 6242 0 1 59438 0.0000168243 0 812 0 0 16144 0 1 110228 0.00000907211 762802 chr7:45614643:T>G ADCY1 NM_021116:p.Leu167Leu NM_021116:c.501T>G EXON1 Unknown significance rs376573772 This variant is a VUS because it does not have enough information. 1 8548 0.000116986 0 4382 0 1 12930 0.0000773395 762803 chr7:45614652:C>T ADCY1 NM_021116:p.Thr170Thr NM_021116:c.510C>T EXON1 Unknown significance rs370830411 This variant is a VUS because it does not have enough information. 0 8556 0 1 4390 0.00022779 1 12946 0.0000772439 1 8642 0.000115714 0 11092 0 0 8272 0 0 6268 0 0 60340 0 0 818 0 0 16166 0 1 111598 0.00000896073 762804 chr7:45614663:A>G ADCY1 NM_021116:p.Tyr174Cys NM_021116:c.521A>G EXON1 Unknown significance rs753183956 This variant is a VUS because it does not have enough information. 1.011 C 0.001 D 0.999 D 0.000002 D 0.999999 D;D 3.7 C 0 8758 0 0 11146 0 0 8326 0 0 6284 0 0 60848 0 0 820 0 1 16192 0.0000617589 1 112374 0.00000889886 762805 chr7:45614671:C>A ADCY1 NM_021116:p.Leu177Met NM_021116:c.529C>A EXON1 Unknown significance rs756596808 This variant is a VUS because it does not have enough information. 0.797 N 0.293 T 0.996 D 0.000021 D 0.999722 D;D 3.7 C 0 8794 0 0 11154 0 0 8342 0 0 6298 0 1 61004 0.0000163924 0 820 0 0 16196 0 1 112608 0.00000888036 762806 chr7:45614685:C>A ADCY1 NM_021116:p.Ser181Arg NM_021116:c.543C>A EXON1 Unknown significance rs778441100 This variant is a VUS because it does not have enough information. 0.797 N 0.022 D 0.009 B 0.000006 D 1 D;N 2.56 C 0 8866 0 0 11210 0 1 8384 0.000119275 0 6282 0 0 61292 0 0 820 0 0 16186 0 1 113040 0.00000884643 762807 chr7:45614685:C>G ADCY1 NM_021116:p.Ser181Arg NM_021116:c.543C>G EXON1 Unknown significance rs778441100 This variant is a VUS because it does not have enough information. 0.797 N 0.022 D 0.009 B 0.000006 D 1 D;N 2.56 C 0 8866 0 0 11210 0 0 8384 0 0 6282 0 0 61292 0 0 820 0 2 16186 0.000123564 2 113040 0.0000176929 762808 chr7:45614693:C>T ADCY1 NM_021116:p.Ala184Val NM_021116:c.551C>T EXON1 Unknown significance rs758041210 This variant is a VUS because it does not have enough information. -0.019 N 0.002 D 0.907 P 0.000251 N 0.999979 D;D 1.88 C 0 8900 0 0 11228 0 0 8398 0 0 6296 0 1 61416 0.0000162824 0 830 0 0 16162 0 1 113230 0.00000883158 762809 chr7:45614697:A>G ADCY1 NM_021116:p.Ile185Met NM_021116:c.555A>G EXON1 Unknown significance rs779732430 This variant is a VUS because it does not have enough information. -0.022 N 0.006 D 0.311 B 0.000032 D 0.995697 D;D 3.7 C 0 8914 0 0 11220 0 0 8400 0 0 6302 0 1 61478 0.000016266 0 828 0 0 16154 0 1 113296 0.00000882644 762810 chr7:45614707:C>T ADCY1 NM_021116:p.Leu189Phe NM_021116:c.565C>T EXON1 Likely benign rs765505992 Pathogenicity is based on prediction data only. 2 out of 6 predictions were pathogenic. 0.797 N 0.259 T 0.011 B 0.049104 N 0.898464 D;D 2.71 C 0 8794 0 0 11216 0 0 8400 0 0 6270 0 1 61338 0.0000163031 0 826 0 0 16088 0 1 112932 0.00000885489 762811 chr7:45614709:C>T ADCY1 NM_021116:p.Leu189Leu NM_021116:c.567C>T EXON1 Unknown significance rs768506366 This variant is a VUS because it does not have enough information. 1 8816 0.00011343 0 11222 0 0 8394 0 0 6270 0 0 61364 0 0 824 0 0 16092 0 1 112982 0.00000885097 762812 chr7:45614742:C>T ADCY1 NM_021116:p.Ala200Ala NM_021116:c.600C>T EXON1 Unknown significance rs780969675 This variant is a VUS because it does not have enough information. 0 8754 0 1 11280 0.0000886525 0 8436 0 0 6288 0 0 61204 0 0 818 0 0 15284 0 1 112064 0.00000892347 762813 chr7:45614744:C>T ADCY1 NM_021116:p.Thr201Ile NM_021116:c.602C>T EXON1 Unknown significance rs748029352 This variant is a VUS because it does not have enough information. 0.864 N 0.398 T 0.001 B 0.000189 D 0.970849 D;D 3.7 C 0 8726 0 0 11274 0 0 8442 0 0 6290 0 1 61188 0.0000163431 0 816 0 0 15180 0 1 111916 0.00000893527 762814 chr7:45614757:C>T ADCY1 NM_021116:p.Ala205Ala NM_021116:c.615C>T EXON1 Unknown significance rs139122316 This variant is a VUS because it does not have enough information. 1 8568 0.000116713 0 4386 0 1 12954 0.0000771962 762815 chr7:45614796:G>A ADCY1 NM_021116:c.639+15G>A INTRON1 Unknown significance rs769649414 This variant is a VUS because it does not have enough information. 0 8342 0 2 11184 0.000178827 0 8390 0 0 6216 0 0 59842 0 0 738 0 0 11354 0 2 106066 0.0000188562 762816 chr7:45614798:A>T ADCY1 NM_021116:c.639+17A>T INTRON1 Unknown significance rs773309750 This variant is a VUS because it does not have enough information. 0 8308 0 0 11188 0 0 8382 0 0 6200 0 10 59778 0.000167286 0 734 0 0 11196 0 10 105786 0.0000945305 762817 chr7:45614807:C>G ADCY1 NM_021116:c.639+26C>G INTRON1 Unknown significance rs199544733 This variant is a VUS because it does not have enough information. 0 8504 0 5 4360 0.00114679 5 12864 0.000388682 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 19 8238 0.00230639 3 11174 0.00026848 0 8356 0 0 6202 0 0 59428 0 0 722 0 0 10448 0 22 104568 0.000210389 762818 chr7:45614814:C>G ADCY1 NM_021116:c.639+33C>G INTRON1 Unknown significance rs771168252 This variant is a VUS because it does not have enough information. 1 8184 0.00012219 0 11154 0 0 8346 0 0 6180 0 0 59210 0 0 716 0 0 9976 0 1 103766 0.00000963707 762819 chr7:45614817:A>G ADCY1 NM_021116:c.639+36A>G INTRON1 Unknown significance rs774777802 This variant is a VUS because it does not have enough information. 0 8148 0 0 11152 0 0 8338 0 0 6172 0 1 59176 0.0000168987 0 710 0 0 9772 0 1 103468 0.00000966482 762820 chr7:45614822:C>T ADCY1 NM_021116:c.639+41C>T INTRON1 Unknown significance rs759838946 This variant is a VUS because it does not have enough information. 0 8048 0 0 11128 0 0 8322 0 0 6126 0 0 58940 0 0 706 0 1 9422 0.000106135 1 102692 0.00000973786 762821 chr7:45614823:T>C ADCY1 NM_021116:c.639+42T>C INTRON1 Unknown significance rs767939227 This variant is a VUS because it does not have enough information. 1 8056 0.000124131 0 11122 0 0 8318 0 0 6142 0 0 58958 0 0 708 0 0 9446 0 1 102750 0.00000973236 762822 chr7:45614825:G>A ADCY1 NM_021116:c.639+44G>A INTRON1 Unknown significance rs776023135 This variant is a VUS because it does not have enough information. 0 8010 0 0 11122 0 0 8308 0 0 6134 0 2 58882 0.0000339662 0 708 0 0 9406 0 2 102570 0.0000194989 762823 chr7:45614826:C>G ADCY1 NM_021116:c.639+45C>G INTRON1 Unknown significance rs761208011 This variant is a VUS because it does not have enough information. 0 7996 0 0 11118 0 0 8300 0 1 6114 0.000163559 0 58784 0 0 700 0 0 9298 0 1 102310 0.00000977422 762824 chr7:45614828:G>A ADCY1 NM_021116:c.639+47G>A INTRON1 Unknown significance rs764551512 This variant is a VUS because it does not have enough information. 762825 chr7:45614848:C>G ADCY1 NM_021116:c.639+67C>G INTRON1 Unknown significance rs529625280 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 762826 chr7:45614859:G>A ADCY1 NM_021116:c.639+78G>A INTRON1 Unknown significance rs548105209 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 762827 chr7:45614874:C>T ADCY1 NM_021116:c.639+93C>T INTRON1 Unknown significance rs569611079 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 2 978 0.002 2 5008 0.000399361 762828 chr7:45614875:G>A ADCY1 NM_021116:c.639+94G>A INTRON1 Benign rs73318930 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 29 1322 0.0219 38 1006 0.0378 22 694 0.0317 0 1008 0 10 978 0.0102 99 5008 0.0197684 762829 chr7:45614906:G>A ADCY1 NM_021116:c.639+125G>A INTRON1 Unknown significance rs568560081 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681 762830 chr7:45614925:C>G ADCY1 NM_021116:c.639+144C>G INTRON1 Unknown significance rs570597916 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681 762831 chr7:45614927:A>G ADCY1 NM_021116:c.639+146A>G INTRON1 Unknown significance rs538774158 This variant is a VUS because it does not have enough information. 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403 762832 chr7:45614958:C>G ADCY1 NM_021116:c.639+177C>G INTRON1 Unknown significance rs554225387 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 1 978 0.001 2 5008 0.000399361 762833 chr7:45614985:C>A ADCY1 NM_021116:c.639+204C>A INTRON1 Unknown significance rs528174506 This variant is a VUS because it does not have enough information. 762834 chr7:45615035:G>A ADCY1 NM_021116:c.639+254G>A INTRON1 Unknown significance rs572378362 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 4 1008 0.004 0 978 0 4 5008 0.000798722 762835 chr7:45615063:G>C ADCY1 NM_021116:c.639+282G>C INTRON1 Unknown significance rs763312122 This variant is a VUS because it does not have enough information. 762836 chr7:45615114:C>T ADCY1 NM_021116:c.639+333C>T INTRON1 Unknown significance rs543041940 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681 762837 chr7:45615137:T>G ADCY1 NM_021116:c.639+356T>G INTRON1 Unknown significance rs764326617 This variant is a VUS because it does not have enough information. 762838 chr7:45615164:C>G ADCY1 NM_021116:c.639+383C>G INTRON1 Unknown significance rs752132116 This variant is a VUS because it does not have enough information. 762839 chr7:45615175:C>T ADCY1 NM_021116:c.639+394C>T INTRON1 Unknown significance rs555345101 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681 762840 chr7:45615183:G>A ADCY1 NM_021116:c.639+402G>A INTRON1 Benign rs373380741 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 0 1322 0 0 1006 0 0 694 0 6 1008 0.006 0 978 0 6 5008 0.00119808 762841 chr7:45615185:C>G ADCY1 NM_021116:c.639+404C>G INTRON1 Benign rs12702148 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 81 1322 0.0613 313 1006 0.3111 199 694 0.2867 474 1008 0.4702 345 978 0.3528 1412 5008 0.281949 762842 chr7:45615193:G>A ADCY1 NM_021116:c.639+412G>A INTRON1 Unknown significance rs375745430 This variant is a VUS because it does not have enough information. 762843 chr7:45615209:C>A ADCY1 NM_021116:c.639+428C>A INTRON1 Unknown significance rs565357511 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681 762844 chr7:45615249:C>T ADCY1 NM_021116:c.639+468C>T INTRON1 Unknown significance rs184559465 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 762845 chr7:45615260:C>T ADCY1 NM_021116:c.639+479C>T INTRON1 Benign rs145162581 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 0 1322 0 12 1006 0.0119 2 694 0.0029 0 1008 0 6 978 0.0061 20 5008 0.00399361 762846 chr7:45615264:G>T ADCY1 NM_021116:c.639+483G>T INTRON1 Unknown significance rs751487247 This variant is a VUS because it does not have enough information. 762847 chr7:45615289:A>T ADCY1 NM_021116:c.639+508A>T INTRON1 Unknown significance rs559375449 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 762848 chr7:45615303:A>C ADCY1 NM_021116:c.639+522A>C INTRON1 Unknown significance rs369011235 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 762849 chr7:45615333:C>T ADCY1 NM_021116:c.639+552C>T INTRON1 Unknown significance rs749959431 This variant is a VUS because it does not have enough information. 762850 chr7:45615382:C>T ADCY1 NM_021116:c.639+601C>T INTRON1 Benign rs189331207 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 14 1322 0.0106 0 1006 0 0 694 0 0 1008 0 0 978 0 14 5008 0.00279553 762851 chr7:45615385:T>A ADCY1 NM_021116:c.639+604T>A INTRON1 Unknown significance rs755627358 This variant is a VUS because it does not have enough information. 762852 chr7:45615399:G>C ADCY1 NM_021116:c.639+618G>C INTRON1 Unknown significance rs779853539 This variant is a VUS because it does not have enough information. 762853 chr7:45615402:G>- ADCY1 NM_021116:c.639+621delG INTRON1 Unknown significance rs534965150 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 2 1008 0.002 0 978 0 3 5008 0.000599042 762854 chr7:45615460:C>T ADCY1 NM_021116:c.639+679C>T INTRON1 Unknown significance rs562902921 This variant is a VUS because it does not have enough information. 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403 762855 chr7:45615478:G>C ADCY1 NM_021116:c.639+697G>C INTRON1 Unknown significance rs369341105 This variant is a VUS because it does not have enough information. 762856 chr7:45615481:C>T ADCY1 NM_021116:c.639+700C>T INTRON1 Unknown significance rs370121629 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 4 1008 0.004 0 978 0 4 5008 0.000798722 762857 chr7:45615482:G>A ADCY1 NM_021116:c.639+701G>A INTRON1 Unknown significance rs552414012 This variant is a VUS because it does not have enough information. 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361 762858 chr7:45615605:T>C ADCY1 NM_021116:c.639+824T>C INTRON1 Benign rs181985809 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 4 1322 0.003 28 1006 0.0278 5 694 0.0072 10 1008 0.0099 101 978 0.1033 148 5008 0.0295527 762859 chr7:45615617:C>T ADCY1 NM_021116:c.639+836C>T INTRON1 Unknown significance rs556886268 This variant is a VUS because it does not have enough information. 762860 chr7:45615627:G>A ADCY1 NM_021116:c.639+846G>A INTRON1 Benign rs7804852 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 32 1322 0.0242 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 34 5008 0.00678914 762861 chr7:45615628:C>T ADCY1 NM_021116:c.639+847C>T INTRON1 Benign rs7804581 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 32 1322 0.0242 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 34 5008 0.00678914 762862 chr7:45615646:G>- ADCY1 NM_021116:c.639+865delG INTRON1 Unknown significance rs200909534 This variant is a VUS because it does not have enough information. 762863 chr7:45615647:T>- ADCY1 NM_021116:c.639+866delT INTRON1 Benign rs11339042 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 685 1322 0.5182 482 1006 0.4791 294 694 0.4236 673 1008 0.6677 603 978 0.6166 2737 5008 0.546526 762864 chr7:45615648:T>G ADCY1 NM_021116:c.639+867T>G INTRON1 Unknown significance rs199943201 This variant is a VUS because it does not have enough information. 762865 chr7:45615676:G>A ADCY1 NM_021116:c.639+895G>A INTRON1 Unknown significance rs113821653 This variant is a VUS because it does not have enough information. 762866 chr7:45615704:G>T ADCY1 NM_021116:c.639+923G>T INTRON1 Unknown significance rs566171167 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 762867 chr7:45615707:G>T ADCY1 NM_021116:c.639+926G>T INTRON1 Unknown significance rs754839666 This variant is a VUS because it does not have enough information. 762868 chr7:45615757:C>T ADCY1 NM_021116:c.639+976C>T INTRON1 Unknown significance rs778618608 This variant is a VUS because it does not have enough information. 762869 chr7:45615765:A>G ADCY1 NM_021116:c.639+984A>G INTRON1 Unknown significance rs539366781 This variant is a VUS because it does not have enough information. 762870 chr7:45615783:C>T ADCY1 NM_021116:c.639+1002C>T INTRON1 Benign rs12702149 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 264 1322 0.1997 400 1006 0.3976 251 694 0.3617 662 1008 0.6567 494 978 0.5051 2071 5008 0.413538 762871 chr7:45615797:GG>- ADCY1 NM_021116:c.639+1016_639+1017delGG INTRON1 Unknown significance rs758751673 This variant is a VUS because it does not have enough information. 762872 chr7:45615803:G>A ADCY1 NM_021116:c.639+1022G>A INTRON1 Unknown significance rs555009719 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 762873 chr7:45615823:A>G ADCY1 NM_021116:c.639+1042A>G INTRON1 Unknown significance rs576474066 This variant is a VUS because it does not have enough information. 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403 762874 chr7:45615829:T>A ADCY1 NM_021116:c.639+1048T>A INTRON1 Unknown significance rs537357782 This variant is a VUS because it does not have enough information. 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042 762875 chr7:45615842:C>G ADCY1 NM_021116:c.639+1061C>G INTRON1 Unknown significance rs565848865 This variant is a VUS because it does not have enough information. 762876 chr7:45615851:G>A ADCY1 NM_021116:c.639+1070G>A INTRON1 Unknown significance rs771972761 This variant is a VUS because it does not have enough information. 762877 chr7:45615860:G>A ADCY1 NM_021116:c.639+1079G>A INTRON1 Unknown significance rs777757323 This variant is a VUS because it does not have enough information. 762878 chr7:45615880:G>A ADCY1 NM_021116:c.639+1099G>A INTRON1 Benign rs77239239 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 38 1322 0.0287 30 1006 0.0298 22 694 0.0317 162 1008 0.1607 104 978 0.1063 356 5008 0.0710863 762879 chr7:45615918:G>A ADCY1 NM_021116:c.639+1137G>A INTRON1 Unknown significance rs756184009 This variant is a VUS because it does not have enough information. 762880 chr7:45615921:TG>- ADCY1 NM_021116:c.639+1140_639+1141delTG INTRON1 Unknown significance rs556672185 This variant is a VUS because it does not have enough information. 6 1322 0.0045 0 1006 0 0 694 0 0 1008 0 0 978 0 6 5008 0.00119808 762881 chr7:45615942:CAGT>- ADCY1 NM_021116:c.639+1161_639+1164delCAGT INTRON1 Benign rs367978525 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 5 1322 0.0038 5 1006 0.005 0 694 0 7 1008 0.0069 47 978 0.0481 64 5008 0.0127796 762882 chr7:45615956:A>G ADCY1 NM_021116:c.639+1175A>G INTRON1 Benign rs4724419 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 1320 1322 0.9985 993 1006 0.9871 688 694 0.9914 1008 1008 1 978 978 1 4987 5008 0.995807 762883 chr7:45615968:A>G ADCY1 NM_021116:c.639+1187A>G INTRON1 Unknown significance rs541609251 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 762884 chr7:45615970:C>A ADCY1 NM_021116:c.639+1189C>A INTRON1 Unknown significance rs757581582 This variant is a VUS because it does not have enough information. 762885 chr7:45615979:G>A ADCY1 NM_021116:c.639+1198G>A INTRON1 Unknown significance rs374189075 This variant is a VUS because it does not have enough information. 762886 chr7:45616041:G>T ADCY1 NM_021116:c.639+1260G>T INTRON1 Unknown significance rs779252024 This variant is a VUS because it does not have enough information. 762887 chr7:45616075:C>T ADCY1 NM_021116:c.639+1294C>T INTRON1 Benign rs11979797 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 164 1322 0.1241 50 1006 0.0497 27 694 0.0389 0 1008 0 7 978 0.0072 248 5008 0.0495208 762888 chr7:45616107:A>G ADCY1 NM_021116:c.639+1326A>G INTRON1 Unknown significance rs763115041 This variant is a VUS because it does not have enough information. 762889 chr7:45616113:G>A ADCY1 NM_021116:c.639+1332G>A INTRON1 Benign rs78436178 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 2 1322 0.0015 9 1006 0.0089 79 694 0.1138 302 1008 0.2996 45 978 0.046 437 5008 0.0872604 762890 chr7:45616131:A>C ADCY1 NM_021116:c.639+1350A>C INTRON1 Benign rs11972954 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 26 1322 0.0197 0 1006 0 0 694 0 0 1008 0 0 978 0 26 5008 0.00519169 762891 chr7:45616187:G>A ADCY1 NM_021116:c.639+1406G>A INTRON1 Unknown significance rs562960145 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 3 1008 0.003 0 978 0 3 5008 0.000599042 762892 chr7:45616198:C>G ADCY1 NM_021116:c.639+1417C>G INTRON1 Unknown significance rs530409969 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681 762893 chr7:45616213:G>T ADCY1 NM_021116:c.639+1432G>T INTRON1 Unknown significance rs376098725 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361 762894 chr7:45616214:C>A ADCY1 NM_021116:c.639+1433C>A INTRON1 Unknown significance rs564404193 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 762895 chr7:45616226:C>T ADCY1 NM_021116:c.639+1445C>T INTRON1 Unknown significance rs528317772 This variant is a VUS because it does not have enough information. 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403 762896 chr7:45616241:C>T ADCY1 NM_021116:c.639+1460C>T INTRON1 Unknown significance rs780587291 This variant is a VUS because it does not have enough information. 762897 chr7:45616280:A>G ADCY1 NM_021116:c.639+1499A>G INTRON1 Benign rs58500623 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 12 1322 0.0091 0 1006 0 3 694 0.0043 0 1008 0 0 978 0 15 5008 0.00299521 762898 chr7:45616293:T>A ADCY1 NM_021116:c.639+1512T>A INTRON1 Unknown significance rs568216723 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681 762899 chr7:45616301:C>G ADCY1 NM_021116:c.639+1520C>G INTRON1 Unknown significance rs536762838 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 2 5008 0.000399361 762900 chr7:45616334:G>C ADCY1 NM_021116:c.639+1553G>C INTRON1 Unknown significance rs548664887 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 762901 chr7:45616336:C>- ADCY1 NM_021116:c.639+1555delC INTRON1 Unknown significance rs747452045 This variant is a VUS because it does not have enough information. 762902 chr7:45616352:C>T ADCY1 NM_021116:c.639+1571C>T INTRON1 Unknown significance rs542371643 This variant is a VUS because it does not have enough information. 762903 chr7:45616365:C>T ADCY1 NM_021116:c.639+1584C>T INTRON1 Unknown significance rs140090608 This variant is a VUS because it does not have enough information. 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403 762904 chr7:45616382:C>T ADCY1 NM_021116:c.639+1601C>T INTRON1 Unknown significance rs747663179 This variant is a VUS because it does not have enough information. 762905 chr7:45616478:C>T ADCY1 NM_021116:c.639+1697C>T INTRON1 Unknown significance rs563745525 This variant is a VUS because it does not have enough information. 762906 chr7:45616494:G>C ADCY1 NM_021116:c.639+1713G>C INTRON1 Unknown significance rs767923548 This variant is a VUS because it does not have enough information. 762907 chr7:45616504:G>C ADCY1 NM_021116:c.639+1723G>C INTRON1 Benign rs6977779 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 14 1322 0.0106 0 1006 0 0 694 0 0 1008 0 0 978 0 14 5008 0.00279553 762908 chr7:45616504:G>T ADCY1 NM_021116:c.639+1723G>T INTRON1 Unknown significance rs6977779 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 3 978 0.0031 3 5008 0.000599042 762909 chr7:45616509:G>A ADCY1 NM_021116:c.639+1728G>A INTRON1 Unknown significance rs750892273 This variant is a VUS because it does not have enough information. 762910 chr7:45616537:A>G ADCY1 NM_021116:c.639+1756A>G INTRON1 Benign rs75813508 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 63 1322 0.0477 19 1006 0.0189 10 694 0.0144 26 1008 0.0258 36 978 0.0368 154 5008 0.0307508 762911 chr7:45616541:T>G ADCY1 NM_021116:c.639+1760T>G INTRON1 Unknown significance rs765935242 This variant is a VUS because it does not have enough information. 762912 chr7:45616563:T>G ADCY1 NM_021116:c.639+1782T>G INTRON1 Unknown significance rs186754300 This variant is a VUS because it does not have enough information. 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403 762913 chr7:45616612:A>G ADCY1 NM_021116:c.639+1831A>G INTRON1 Unknown significance rs553153862 This variant is a VUS because it does not have enough information. 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361 762914 chr7:45616674:G>C ADCY1 NM_021116:c.639+1893G>C INTRON1 Unknown significance rs574658249 This variant is a VUS because it does not have enough information. 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361 762915 chr7:45616676:C>T ADCY1 NM_021116:c.639+1895C>T INTRON1 Unknown significance rs190117847 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 2 5008 0.000399361 762916 chr7:45616694:A>G ADCY1 NM_021116:c.639+1913A>G INTRON1 Benign rs150023156 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 14 1322 0.0106 0 1006 0 0 694 0 1 1008 0.001 0 978 0 15 5008 0.00299521 762917 chr7:45616736:G>T ADCY1 NM_021116:c.639+1955G>T INTRON1 Unknown significance rs574942411 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 762918 chr7:45616761:T>C ADCY1 NM_021116:c.639+1980T>C INTRON1 Unknown significance rs762528898 This variant is a VUS because it does not have enough information. 762919 chr7:45616772:A>G ADCY1 NM_021116:c.639+1991A>G INTRON1 Unknown significance rs545775759 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 762920 chr7:45616774:G>A ADCY1 NM_021116:c.639+1993G>A INTRON1 Unknown significance rs563887572 This variant is a VUS because it does not have enough information. 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 762921 chr7:45616812:A>G ADCY1 NM_021116:c.639+2031A>G INTRON1 Unknown significance rs145343321 This variant is a VUS because it does not have enough information. 4 1322 0.003 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 5 5008 0.000998403 762922 chr7:45616861:A>G ADCY1 NM_021116:c.639+2080A>G INTRON1 Unknown significance rs753373655 This variant is a VUS because it does not have enough information. 762923 chr7:45616873:C>G ADCY1 NM_021116:c.639+2092C>G INTRON1 Unknown significance rs540125037 This variant is a VUS because it does not have enough information. 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361 762924 chr7:45616898:A>G ADCY1 NM_021116:c.639+2117A>G INTRON1 Unknown significance rs561883607 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681 762925 chr7:45616909:C>T ADCY1 NM_021116:c.639+2128C>T INTRON1 Unknown significance rs574109465 This variant is a VUS because it does not have enough information. 762926 chr7:45616935:T>C ADCY1 NM_021116:c.639+2154T>C INTRON1 Unknown significance rs770695831 This variant is a VUS because it does not have enough information. 762927 chr7:45616947:->G ADCY1 NM_021116:c.639+2166_639+2167insG INTRON1 Unknown significance rs34673212 This variant is a VUS because it does not have enough information. 762928 chr7:45616951:A>T ADCY1 NM_021116:c.639+2170A>T INTRON1 Unknown significance rs778626987 This variant is a VUS because it does not have enough information. 762929 chr7:45616955:A>G ADCY1 NM_021116:c.639+2174A>G INTRON1 Unknown significance rs529087120 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681 762930 chr7:45616966:C>T ADCY1 NM_021116:c.639+2185C>T INTRON1 Unknown significance rs371472241 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 4 1008 0.004 0 978 0 4 5008 0.000798722 762931 chr7:45616970:C>G ADCY1 NM_021116:c.639+2189C>G INTRON1 Unknown significance rs752495516 This variant is a VUS because it does not have enough information. 762932 chr7:45616999:A>G ADCY1 NM_021116:c.639+2218A>G INTRON1 Benign rs149228627 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 4 1322 0.003 28 1006 0.0278 5 694 0.0072 10 1008 0.0099 101 978 0.1033 148 5008 0.0295527 762933 chr7:45617009:C>T ADCY1 NM_021116:c.639+2228C>T INTRON1 Unknown significance rs530852227 This variant is a VUS because it does not have enough information. 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403 762934 chr7:45617015:A>G ADCY1 NM_021116:c.639+2234A>G INTRON1 Unknown significance rs552551538 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681 762935 chr7:45617059:T>C ADCY1 NM_021116:c.639+2278T>C INTRON1 Unknown significance rs570710669 This variant is a VUS because it does not have enough information. 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 762936 chr7:45617060:C>T ADCY1 NM_021116:c.639+2279C>T INTRON1 Unknown significance rs777580844 This variant is a VUS because it does not have enough information. 762937 chr7:45617094:G>A ADCY1 NM_021116:c.639+2313G>A INTRON1 Unknown significance rs535601658 This variant is a VUS because it does not have enough information. 762938 chr7:45617109:C>T ADCY1 NM_021116:c.639+2328C>T INTRON1 Unknown significance rs369207439 This variant is a VUS because it does not have enough information. 762939 chr7:45617130:T>C ADCY1 NM_021116:c.639+2349T>C INTRON1 Benign rs535349622 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 8 1322 0.0061 0 1006 0 0 694 0 0 1008 0 0 978 0 8 5008 0.00159744 762940 chr7:45617131:C>T ADCY1 NM_021116:c.639+2350C>T INTRON1 Benign rs143386069 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 0 1322 0 0 1006 0 0 694 0 14 1008 0.0139 0 978 0 14 5008 0.00279553 762941 chr7:45617192:G>A ADCY1 NM_021116:c.639+2411G>A INTRON1 Unknown significance rs568342942 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681 762942 chr7:45617279:A>G ADCY1 NM_021116:c.639+2498A>G INTRON1 Unknown significance rs535648638 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 762943 chr7:45617293:C>T ADCY1 NM_021116:c.639+2512C>T INTRON1 Unknown significance rs556678018 This variant is a VUS because it does not have enough information. 2 1322 0.0015 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 3 5008 0.000599042 762944 chr7:45617319:C>G ADCY1 NM_021116:c.639+2538C>G INTRON1 Unknown significance rs769885334 This variant is a VUS because it does not have enough information. 762945 chr7:45617372:T>A ADCY1 NM_021116:c.639+2591T>A INTRON1 Unknown significance rs759466494 This variant is a VUS because it does not have enough information. 762946 chr7:45617383:T>G ADCY1 NM_021116:c.639+2602T>G INTRON1 Benign rs78338109 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 0 1322 0 1 1006 0.001 15 694 0.0216 125 1008 0.124 34 978 0.0348 175 5008 0.0349441 762947 chr7:45617405:C>T ADCY1 NM_021116:c.639+2624C>T INTRON1 Benign rs115342333 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 13 1322 0.0098 0 1006 0 0 694 0 0 1008 0 0 978 0 13 5008 0.00259585 762948 chr7:45617408:G>T ADCY1 NM_021116:c.639+2627G>T INTRON1 Unknown significance rs749336657 This variant is a VUS because it does not have enough information. 762949 chr7:45617422:G>A ADCY1 NM_021116:c.639+2641G>A INTRON1 Unknown significance rs557753945 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 762950 chr7:45617433:C>T ADCY1 NM_021116:c.639+2652C>T INTRON1 Benign rs115787895 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 11 1322 0.0083 0 1006 0 0 694 0 0 1008 0 0 978 0 11 5008 0.00219649 762951 chr7:45617472:G>A ADCY1 NM_021116:c.639+2691G>A INTRON1 Unknown significance rs768817045 This variant is a VUS because it does not have enough information. 762952 chr7:45617488:T>A ADCY1 NM_021116:c.639+2707T>A INTRON1 Unknown significance rs181405465 This variant is a VUS because it does not have enough information. 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403 762953 chr7:45617493:C>A ADCY1 NM_021116:c.639+2712C>A INTRON1 Unknown significance rs752707760 This variant is a VUS because it does not have enough information. 762954 chr7:45617513:C>T ADCY1 NM_021116:c.639+2732C>T INTRON1 Unknown significance rs774574445 This variant is a VUS because it does not have enough information. 762955 chr7:45617518:G>A ADCY1 NM_021116:c.639+2737G>A INTRON1 Benign rs185937564 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 7 1322 0.0053 0 1006 0 0 694 0 0 1008 0 0 978 0 7 5008 0.00139776 762956 chr7:45617536:T>A ADCY1 NM_021116:c.639+2755T>A INTRON1 Unknown significance rs760771734 This variant is a VUS because it does not have enough information. 762957 chr7:45617565:G>A ADCY1 NM_021116:c.639+2784G>A INTRON1 Unknown significance rs529150659 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681 762958 chr7:45617596:C>A ADCY1 NM_021116:c.639+2815C>A INTRON1 Unknown significance rs544412603 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681 762959 chr7:45617628:G>A ADCY1 NM_021116:c.639+2847G>A INTRON1 Benign rs79268889 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 0 1322 0 1 1006 0.001 15 694 0.0216 125 1008 0.124 34 978 0.0348 175 5008 0.0349441 762960 chr7:45617630:A>G ADCY1 NM_021116:c.639+2849A>G INTRON1 Unknown significance rs201513838 This variant is a VUS because it does not have enough information. 762961 chr7:45617640:C>G ADCY1 NM_021116:c.639+2859C>G INTRON1 Unknown significance rs531037916 This variant is a VUS because it does not have enough information. 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 762962 chr7:45617661:C>G ADCY1 NM_021116:c.639+2880C>G INTRON1 Unknown significance rs552361512 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 0 978 0 0 5008 0 762963 chr7:45617698:C>T ADCY1 NM_021116:c.639+2917C>T INTRON1 Unknown significance rs146795025 This variant is a VUS because it does not have enough information. 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042 762964 chr7:45617722:C>T ADCY1 NM_021116:c.639+2941C>T INTRON1 Unknown significance rs528453192 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 762965 chr7:45617752:G>C ADCY1 NM_021116:c.639+2971G>C INTRON1 Unknown significance rs772437596 This variant is a VUS because it does not have enough information. 762966 chr7:45617815:C>T ADCY1 NM_021116:c.639+3034C>T INTRON1 Unknown significance rs773874157 This variant is a VUS because it does not have enough information. 762967 chr7:45617845:C>T ADCY1 NM_021116:c.639+3064C>T INTRON1 Unknown significance rs546935477 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 762968 chr7:45617859:C>A ADCY1 NM_021116:c.639+3078C>A INTRON1 Unknown significance rs761311232 This variant is a VUS because it does not have enough information. 762969 chr7:45617862:T>G ADCY1 NM_021116:c.639+3081T>G INTRON1 Unknown significance rs568403788 This variant is a VUS because it does not have enough information. 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 762970 chr7:45617881:C>A ADCY1 NM_021116:c.639+3100C>A INTRON1 Unknown significance rs535708478 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681 762971 chr7:45617893:G>A ADCY1 NM_021116:c.639+3112G>A INTRON1 Unknown significance rs140481106 This variant is a VUS because it does not have enough information. 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 762972 chr7:45617901:->G ADCY1 NM_021116:c.639+3120_639+3121insG INTRON1 Benign rs565184011 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 11 1322 0.0083 1 1006 0.001 1 694 0.0014 0 1008 0 0 978 0 13 5008 0.00259585 762974 chr7:45617901:G>A ADCY1 NM_021116:c.639+3120G>A INTRON1 Unknown significance rs77226271 This variant is a VUS because it does not have enough information. 762973 chr7:45617901:G>T ADCY1 NM_021116:c.639+3120G>T INTRON1 Unknown significance rs77226271 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 3 978 0.0031 3 5008 0.000599042 762975 chr7:45617902:G>C ADCY1 NM_021116:c.639+3121G>C INTRON1 Unknown significance rs766959182 This variant is a VUS because it does not have enough information. 762976 chr7:45617937:A>G ADCY1 NM_021116:c.639+3156A>G INTRON1 Unknown significance rs539532212 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 762977 chr7:45617981:A>G ADCY1 NM_021116:c.639+3200A>G INTRON1 Benign rs10807926 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 461 1322 0.3487 448 1006 0.4453 264 694 0.3804 514 1008 0.5099 499 978 0.5102 2186 5008 0.436502 762978 chr7:45617997:C>A ADCY1 NM_021116:c.639+3216C>A INTRON1 Unknown significance rs572826798 This variant is a VUS because it does not have enough information. 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403 762979 chr7:45618001:C>G ADCY1 NM_021116:c.639+3220C>G INTRON1 Unknown significance rs759076039 This variant is a VUS because it does not have enough information. 762980 chr7:45618005:C>T ADCY1 NM_021116:c.639+3224C>T INTRON1 Benign rs10951823 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 473 1322 0.3578 478 1006 0.4751 286 694 0.4121 672 1008 0.6667 603 978 0.6166 2512 5008 0.501597 762981 chr7:45618083:G>C ADCY1 NM_021116:c.639+3302G>C INTRON1 Benign rs10951824 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 177 1322 0.1339 351 1006 0.3489 220 694 0.317 474 1008 0.4702 355 978 0.363 1577 5008 0.314896 762982 chr7:45618116:T>C ADCY1 NM_021116:c.639+3335T>C INTRON1 Unknown significance rs573994197 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 762983 chr7:45618151:G>A ADCY1 NM_021116:c.639+3370G>A INTRON1 Unknown significance rs544472918 This variant is a VUS because it does not have enough information. 0 1322 0 2 1006 0.002 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361 762984 chr7:45618182:T>C ADCY1 NM_021116:c.639+3401T>C INTRON1 Unknown significance rs371761404 This variant is a VUS because it does not have enough information. 762985 chr7:45618230:G>T ADCY1 NM_021116:c.639+3449G>T INTRON1 Unknown significance rs562725069 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681 762986 chr7:45618273:G>T ADCY1 NM_021116:c.639+3492G>T INTRON1 Unknown significance rs145709267 This variant is a VUS because it does not have enough information. 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 762987 chr7:45618288:C>A ADCY1 NM_021116:c.639+3507C>A INTRON1 Unknown significance rs138278818 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 762988 chr7:45618303:C>T ADCY1 NM_021116:c.639+3522C>T INTRON1 Unknown significance rs568106690 This variant is a VUS because it does not have enough information. 762989 chr7:45618304:G>A ADCY1 NM_021116:c.639+3523G>A INTRON1 Unknown significance rs564419630 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 762990 chr7:45618320:C>T ADCY1 NM_021116:c.639+3539C>T INTRON1 Unknown significance rs548347333 This variant is a VUS because it does not have enough information. 762991 chr7:45618347:G>A ADCY1 NM_021116:c.639+3566G>A INTRON1 Unknown significance rs528526674 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 3 1008 0.003 0 978 0 3 5008 0.000599042 762992 chr7:45618363:A>G ADCY1 NM_021116:c.639+3582A>G INTRON1 Unknown significance rs546596897 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 762993 chr7:45618378:C>A ADCY1 NM_021116:c.639+3597C>A INTRON1 Unknown significance rs751334807 This variant is a VUS because it does not have enough information. 762994 chr7:45618390:T>A ADCY1 NM_021116:c.639+3609T>A INTRON1 Unknown significance rs757226648 This variant is a VUS because it does not have enough information. 762996 chr7:45618396:T>G ADCY1 NM_021116:c.639+3615T>G INTRON1 Unknown significance rs561698330 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 762995 chr7:45618396:TCC>- ADCY1 NM_021116:c.639+3615_639+3617delTCC INTRON1 Unknown significance rs796924130 This variant is a VUS because it does not have enough information. 762997 chr7:45618407:C>G ADCY1 NM_021116:c.639+3626C>G INTRON1 Unknown significance rs781092341 This variant is a VUS because it does not have enough information. 762998 chr7:45618416:T>C ADCY1 NM_021116:c.639+3635T>C INTRON1 Unknown significance rs529562852 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 762999 chr7:45618436:C>T ADCY1 NM_021116:c.639+3655C>T INTRON1 Unknown significance rs190789844 This variant is a VUS because it does not have enough information. 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403 763000 chr7:45618439:C>G ADCY1 NM_021116:c.639+3658C>G INTRON1 Benign rs4529350 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 213 1322 0.1611 78 1006 0.0775 34 694 0.049 10 1008 0.0099 108 978 0.1104 443 5008 0.0884585 763001 chr7:45618442:T>G ADCY1 NM_021116:c.639+3661T>G INTRON1 Unknown significance rs569788915 This variant is a VUS because it does not have enough information. 763002 chr7:45618458:C>T ADCY1 NM_021116:c.639+3677C>T INTRON1 Unknown significance rs780489296 This variant is a VUS because it does not have enough information. 763003 chr7:45618481:->T ADCY1 NM_021116:c.639+3700_639+3701insT INTRON1 Unknown significance rs35406812 This variant is a VUS because it does not have enough information. 763004 chr7:45618492:A>G ADCY1 NM_021116:c.639+3711A>G INTRON1 Benign rs141736735 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 0 1322 0 0 1006 0 0 694 0 15 1008 0.0149 2 978 0.002 17 5008 0.00339457 763005 chr7:45618513:T>C ADCY1 NM_021116:c.639+3732T>C INTRON1 Benign rs78344730 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 0 1322 0 1 1006 0.001 15 694 0.0216 125 1008 0.124 34 978 0.0348 175 5008 0.0349441 763006 chr7:45618531:T>G ADCY1 NM_021116:c.639+3750T>G INTRON1 Unknown significance rs547084374 This variant is a VUS because it does not have enough information. 763007 chr7:45618538:C>T ADCY1 NM_021116:c.639+3757C>T INTRON1 Unknown significance rs748349744 This variant is a VUS because it does not have enough information. 763008 chr7:45618558:G>A ADCY1 NM_021116:c.639+3777G>A INTRON1 Unknown significance rs772158709 This variant is a VUS because it does not have enough information. 763009 chr7:45618570:T>G ADCY1 NM_021116:c.639+3789T>G INTRON1 Benign rs184169017 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 0 1322 0 0 1006 0 0 694 0 7 1008 0.0069 0 978 0 7 5008 0.00139776 763010 chr7:45618622:C>T ADCY1 NM_021116:c.639+3841C>T INTRON1 Benign rs74698704 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 9 1322 0.0068 29 1006 0.0288 7 694 0.0101 37 1008 0.0367 67 978 0.0685 149 5008 0.0297524 763011 chr7:45618631:G>A ADCY1 NM_021116:c.639+3850G>A INTRON1 Benign rs187561557 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 0 1322 0 0 1006 0 0 694 0 6 1008 0.006 0 978 0 6 5008 0.00119808 763012 chr7:45618640:C>G ADCY1 NM_021116:c.639+3859C>G INTRON1 Unknown significance rs150153106 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763013 chr7:45618671:C>T ADCY1 NM_021116:c.639+3890C>T INTRON1 Unknown significance rs59442380 This variant is a VUS because it does not have enough information. 763014 chr7:45618690:C>T ADCY1 NM_021116:c.639+3909C>T INTRON1 Unknown significance rs538153526 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681 763015 chr7:45618732:C>T ADCY1 NM_021116:c.639+3951C>T INTRON1 Benign rs79515181 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 9 1322 0.0068 29 1006 0.0288 7 694 0.0101 37 1008 0.0367 67 978 0.0685 149 5008 0.0297524 763016 chr7:45618737:A>C ADCY1 NM_021116:c.639+3956A>C INTRON1 Unknown significance rs577814302 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 763017 chr7:45618746:G>T ADCY1 NM_021116:c.639+3965G>T INTRON1 Unknown significance rs771626361 This variant is a VUS because it does not have enough information. 763018 chr7:45618751:A>G ADCY1 NM_021116:c.639+3970A>G INTRON1 Unknown significance rs569784709 This variant is a VUS because it does not have enough information. 763019 chr7:45618786:T>C ADCY1 NM_021116:c.639+4005T>C INTRON1 Unknown significance rs138584557 This variant is a VUS because it does not have enough information. 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042 763020 chr7:45618788:G>A ADCY1 NM_021116:c.639+4007G>A INTRON1 Benign rs76835720 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 63 1322 0.0477 19 1006 0.0189 10 694 0.0144 26 1008 0.0258 36 978 0.0368 154 5008 0.0307508 763021 chr7:45618802:C>T ADCY1 NM_021116:c.639+4021C>T INTRON1 Unknown significance rs149333919 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763022 chr7:45618823:A>G ADCY1 NM_021116:c.639+4042A>G INTRON1 Unknown significance rs540300058 This variant is a VUS because it does not have enough information. 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763023 chr7:45618826:C>T ADCY1 NM_021116:c.639+4045C>T INTRON1 Unknown significance rs561759734 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 763024 chr7:45618842:G>A ADCY1 NM_021116:c.639+4061G>A INTRON1 Unknown significance rs191203239 This variant is a VUS because it does not have enough information. 0 1322 0 3 1006 0.003 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042 763025 chr7:45618867:A>C ADCY1 NM_021116:c.639+4086A>C INTRON1 Unknown significance rs551288572 This variant is a VUS because it does not have enough information. 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403 763026 chr7:45618868:C>G ADCY1 NM_021116:c.639+4087C>G INTRON1 Benign rs76323096 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 18 1322 0.0136 0 1006 0 0 694 0 0 1008 0 0 978 0 18 5008 0.00359425 763027 chr7:45618882:G>A ADCY1 NM_021116:c.639+4101G>A INTRON1 Unknown significance rs111244229 This variant is a VUS because it does not have enough information. 763028 chr7:45618958:G>T ADCY1 NM_021116:c.639+4177G>T INTRON1 Unknown significance rs533617804 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 763029 chr7:45618962:C>T ADCY1 NM_021116:c.639+4181C>T INTRON1 Unknown significance rs551694790 This variant is a VUS because it does not have enough information. 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763030 chr7:45618986:C>T ADCY1 NM_021116:c.639+4205C>T INTRON1 Unknown significance rs567009174 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 763031 chr7:45618987:G>C ADCY1 NM_021116:c.639+4206G>C INTRON1 Unknown significance rs527405220 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 2 5008 0.000399361 763033 chr7:45619019:C>G ADCY1 NM_021116:c.639+4238C>G INTRON1 Unknown significance rs549066278 This variant is a VUS because it does not have enough information. 763032 chr7:45619019:C>T ADCY1 NM_021116:c.639+4238C>T INTRON1 Unknown significance rs549066278 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681 763034 chr7:45619031:T>C ADCY1 NM_021116:c.639+4250T>C INTRON1 Benign rs867582 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 457 1322 0.3457 448 1006 0.4453 264 694 0.3804 510 1008 0.506 499 978 0.5102 2178 5008 0.434904 763035 chr7:45619072:C>A ADCY1 NM_021116:c.639+4291C>A INTRON1 Unknown significance rs537837202 This variant is a VUS because it does not have enough information. 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042 763036 chr7:45619083:C>T ADCY1 NM_021116:c.639+4302C>T INTRON1 Unknown significance rs556461975 This variant is a VUS because it does not have enough information. 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763037 chr7:45619111:C>T ADCY1 NM_021116:c.639+4330C>T INTRON1 Unknown significance rs368508495 This variant is a VUS because it does not have enough information. 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763038 chr7:45619116:A>G ADCY1 NM_021116:c.639+4335A>G INTRON1 Unknown significance rs182576149 This variant is a VUS because it does not have enough information. 0 1322 0 2 1006 0.002 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361 763039 chr7:45619119:T>C ADCY1 NM_021116:c.639+4338T>C INTRON1 Benign rs2877339 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 490 1322 0.3707 478 1006 0.4751 286 694 0.4121 672 1008 0.6667 603 978 0.6166 2529 5008 0.504992 763040 chr7:45619169:C>A ADCY1 NM_021116:c.639+4388C>A INTRON1 Unknown significance rs372822877 This variant is a VUS because it does not have enough information. 763041 chr7:45619200:C>T ADCY1 NM_021116:c.639+4419C>T INTRON1 Unknown significance rs187003728 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763042 chr7:45619203:C>T ADCY1 NM_021116:c.639+4422C>T INTRON1 Unknown significance rs540358183 This variant is a VUS because it does not have enough information. 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763043 chr7:45619224:C>T ADCY1 NM_021116:c.639+4443C>T INTRON1 Unknown significance rs537338513 This variant is a VUS because it does not have enough information. 763044 chr7:45619246:G>A ADCY1 NM_021116:c.639+4465G>A INTRON1 Benign rs117074744 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 4 1322 0.003 29 1006 0.0288 5 694 0.0072 10 1008 0.0099 101 978 0.1033 149 5008 0.0297524 763045 chr7:45619250:T>G ADCY1 NM_021116:c.639+4469T>G INTRON1 Unknown significance rs750334644 This variant is a VUS because it does not have enough information. 763046 chr7:45619360:G>A ADCY1 NM_021116:c.639+4579G>A INTRON1 Unknown significance rs573747109 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681 763047 chr7:45619362:C>A ADCY1 NM_021116:c.639+4581C>A INTRON1 Benign rs114564186 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 10 1322 0.0076 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 11 5008 0.00219649 763048 chr7:45619380:T>A ADCY1 NM_021116:c.639+4599T>A INTRON1 Unknown significance rs772027171 This variant is a VUS because it does not have enough information. 763049 chr7:45619440:G>A ADCY1 NM_021116:c.639+4659G>A INTRON1 Unknown significance rs562862759 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 2 978 0.002 4 5008 0.000798722 763050 chr7:45619464:G>T ADCY1 NM_021116:c.639+4683G>T INTRON1 Unknown significance rs533461200 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 4 978 0.0041 4 5008 0.000798722 763051 chr7:45619520:T>A ADCY1 NM_021116:c.639+4739T>A INTRON1 Benign rs1879591 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 0 1322 0 1 1006 0.001 15 694 0.0216 125 1008 0.124 34 978 0.0348 175 5008 0.0349441 763052 chr7:45619542:C>T ADCY1 NM_021116:c.639+4761C>T INTRON1 Unknown significance rs560684379 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763053 chr7:45619545:C>- ADCY1 NM_021116:c.639+4764delC INTRON1 Unknown significance rs752619537 This variant is a VUS because it does not have enough information. 763054 chr7:45619551:C>T ADCY1 NM_021116:c.639+4770C>T INTRON1 Unknown significance rs558892121 This variant is a VUS because it does not have enough information. 763055 chr7:45619557:C>G ADCY1 NM_021116:c.639+4776C>G INTRON1 Benign rs527871872 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 0 1322 0 0 1006 0 0 694 0 0 1008 0 9 978 0.0092 9 5008 0.00179712 763056 chr7:45619561:C>A ADCY1 NM_021116:c.639+4780C>A INTRON1 Unknown significance rs71537753 This variant is a VUS because it does not have enough information. 763057 chr7:45619569:G>C ADCY1 NM_021116:c.639+4788G>C INTRON1 Unknown significance rs867516 This variant is a VUS because it does not have enough information. 763058 chr7:45619590:G>A ADCY1 NM_021116:c.639+4809G>A INTRON1 Benign rs116636770 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 12 1322 0.0091 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 13 5008 0.00259585 763059 chr7:45619694:A>C ADCY1 NM_021116:c.639+4913A>C INTRON1 Unknown significance rs139481487 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763060 chr7:45619706:A>G ADCY1 NM_021116:c.639+4925A>G INTRON1 Unknown significance rs375927852 This variant is a VUS because it does not have enough information. 763061 chr7:45619743:G>A ADCY1 NM_021116:c.639+4962G>A INTRON1 Unknown significance rs531394989 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681 763062 chr7:45619764:G>A ADCY1 NM_021116:c.639+4983G>A INTRON1 Unknown significance rs779095183 This variant is a VUS because it does not have enough information. 763063 chr7:45619771:G>C ADCY1 NM_021116:c.639+4990G>C INTRON1 Unknown significance rs576866878 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681 763064 chr7:45619805:G>T ADCY1 NM_021116:c.639+5024G>T INTRON1 Unknown significance rs748142473 This variant is a VUS because it does not have enough information. 763065 chr7:45619848:C>A ADCY1 NM_021116:c.639+5067C>A INTRON1 Unknown significance rs758757538 This variant is a VUS because it does not have enough information. 763066 chr7:45619852:G>T ADCY1 NM_021116:c.639+5071G>T INTRON1 Unknown significance rs571193077 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681 763067 chr7:45619868:G>T ADCY1 NM_021116:c.639+5087G>T INTRON1 Unknown significance rs535598024 This variant is a VUS because it does not have enough information. 763068 chr7:45619903:T>C ADCY1 NM_021116:c.639+5122T>C INTRON1 Unknown significance rs143374629 This variant is a VUS because it does not have enough information. 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763069 chr7:45619941:T>A ADCY1 NM_021116:c.639+5160T>A INTRON1 Unknown significance rs778130897 This variant is a VUS because it does not have enough information. 763070 chr7:45619970:AG>- ADCY1 NM_021116:c.639+5189_639+5190delAG INTRON1 Benign rs563791445 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 0 1322 0 0 1006 0 0 694 0 0 1008 0 7 978 0.0072 7 5008 0.00139776 763071 chr7:45619971:G>T ADCY1 NM_021116:c.639+5190G>T INTRON1 Unknown significance rs554015132 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 3 978 0.0031 3 5008 0.000599042 763072 chr7:45620020:C>T ADCY1 NM_021116:c.639+5239C>T INTRON1 Benign rs191834124 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 12 1322 0.0091 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 13 5008 0.00259585 763073 chr7:45620031:A>G ADCY1 NM_021116:c.639+5250A>G INTRON1 Unknown significance rs147166821 This variant is a VUS because it does not have enough information. 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763074 chr7:45620094:C>T ADCY1 NM_021116:c.639+5313C>T INTRON1 Unknown significance rs764152495 This variant is a VUS because it does not have enough information. 763075 chr7:45620114:T>C ADCY1 NM_021116:c.639+5333T>C INTRON1 Unknown significance rs555483733 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681 763076 chr7:45620123:C>A ADCY1 NM_021116:c.639+5342C>A INTRON1 Unknown significance rs557509592 This variant is a VUS because it does not have enough information. 763077 chr7:45620129:T>A ADCY1 NM_021116:c.639+5348T>A INTRON1 Unknown significance rs776571194 This variant is a VUS because it does not have enough information. 763078 chr7:45620138:C>G ADCY1 NM_021116:c.639+5357C>G INTRON1 Unknown significance rs771358741 This variant is a VUS because it does not have enough information. 763079 chr7:45620221:C>T ADCY1 NM_021116:c.639+5440C>T INTRON1 Benign rs575945033 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 0 1322 0 1 1006 0.001 1 694 0.0014 0 1008 0 8 978 0.0082 10 5008 0.00199681 763080 chr7:45620228:C>T ADCY1 NM_021116:c.639+5447C>T INTRON1 Unknown significance rs746338322 This variant is a VUS because it does not have enough information. 763081 chr7:45620241:C>T ADCY1 NM_021116:c.639+5460C>T INTRON1 Unknown significance rs544648503 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763082 chr7:45620282:G>A ADCY1 NM_021116:c.639+5501G>A INTRON1 Benign rs79597784 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 63 1322 0.0477 19 1006 0.0189 10 694 0.0144 27 1008 0.0268 36 978 0.0368 155 5008 0.0309505 763083 chr7:45620286:G>A ADCY1 NM_021116:c.639+5505G>A INTRON1 Benign rs79941245 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 63 1322 0.0477 19 1006 0.0189 10 694 0.0144 27 1008 0.0268 36 978 0.0368 155 5008 0.0309505 763084 chr7:45620306:C>T ADCY1 NM_021116:c.639+5525C>T INTRON1 Benign rs140445635 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 11 1322 0.0083 0 1006 0 0 694 0 0 1008 0 0 978 0 11 5008 0.00219649 763085 chr7:45620310:A>T ADCY1 NM_021116:c.639+5529A>T INTRON1 Unknown significance rs184426057 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361 763086 chr7:45620313:G>T ADCY1 NM_021116:c.639+5532G>T INTRON1 Unknown significance rs573588083 This variant is a VUS because it does not have enough information. 763087 chr7:45620321:G>- ADCY1 NM_021116:c.639+5540delG INTRON1 Unknown significance rs370784954 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 3 978 0.0031 3 5008 0.000599042 763088 chr7:45620324:G>A ADCY1 NM_021116:c.639+5543G>A INTRON1 Unknown significance rs142108148 This variant is a VUS because it does not have enough information. 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042 763089 chr7:45620324:G>T ADCY1 NM_021116:c.639+5543G>T INTRON1 Unknown significance rs142108148 This variant is a VUS because it does not have enough information. 763090 chr7:45620343:T>C ADCY1 NM_021116:c.639+5562T>C INTRON1 Unknown significance rs543253027 This variant is a VUS because it does not have enough information. 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403 763091 chr7:45620348:C>G ADCY1 NM_021116:c.639+5567C>G INTRON1 Benign rs80276915 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 51 1322 0.0386 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 53 5008 0.0105831 763092 chr7:45620363:A>G ADCY1 NM_021116:c.639+5582A>G INTRON1 Unknown significance rs773925007 This variant is a VUS because it does not have enough information. 763093 chr7:45620383:G>A ADCY1 NM_021116:c.639+5602G>A INTRON1 Unknown significance rs540191334 This variant is a VUS because it does not have enough information. 763094 chr7:45620385:->ATCT ADCY1 NM_021116:c.639+5604_639+5605insATCT INTRON1 Unknown significance rs371227177 This variant is a VUS because it does not have enough information. 763095 chr7:45620393:G>A ADCY1 NM_021116:c.639+5612G>A INTRON1 Unknown significance rs531327443 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 763096 chr7:45620420:->A ADCY1 NM_021116:c.639+5639_639+5640insA INTRON1 Unknown significance rs35760107 This variant is a VUS because it does not have enough information. 763097 chr7:45620441:C>T ADCY1 NM_021116:c.639+5660C>T INTRON1 Unknown significance rs767251105 This variant is a VUS because it does not have enough information. 763098 chr7:45620455:C>T ADCY1 NM_021116:c.639+5674C>T INTRON1 Unknown significance rs549811766 This variant is a VUS because it does not have enough information. 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763099 chr7:45620462:C>T ADCY1 NM_021116:c.639+5681C>T INTRON1 Unknown significance rs750159088 This variant is a VUS because it does not have enough information. 763100 chr7:45620491:TGCC>- ADCY1 NM_021116:c.639+5710_639+5713delTGCC INTRON1 Unknown significance rs371795946 This variant is a VUS because it does not have enough information. 763101 chr7:45620521:T>C ADCY1 NM_021116:c.639+5740T>C INTRON1 Unknown significance rs187606844 This variant is a VUS because it does not have enough information. 763102 chr7:45620522:A>G ADCY1 NM_021116:c.639+5741A>G INTRON1 Unknown significance rs193068873 This variant is a VUS because it does not have enough information. 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042 763103 chr7:45620541:G>A ADCY1 NM_021116:c.639+5760G>A INTRON1 Unknown significance rs766219065 This variant is a VUS because it does not have enough information. 763104 chr7:45620552:G>C ADCY1 NM_021116:c.639+5771G>C INTRON1 Benign rs114233764 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 15 1322 0.0113 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 16 5008 0.00319489 763105 chr7:45620591:G>C ADCY1 NM_021116:c.639+5810G>C INTRON1 Unknown significance rs752044433 This variant is a VUS because it does not have enough information. 763106 chr7:45620595:C>T ADCY1 NM_021116:c.639+5814C>T INTRON1 Unknown significance rs185852821 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 3 1008 0.003 0 978 0 3 5008 0.000599042 763107 chr7:45620616:C>G ADCY1 NM_021116:c.639+5835C>G INTRON1 Benign rs77961100 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 37 1322 0.028 5 1006 0.005 4 694 0.0058 0 1008 0 0 978 0 46 5008 0.0091853 763108 chr7:45620620:G>A ADCY1 NM_021116:c.639+5839G>A INTRON1 Unknown significance rs550436970 This variant is a VUS because it does not have enough information. 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763109 chr7:45620640:C>T ADCY1 NM_021116:c.639+5859C>T INTRON1 Benign rs115113253 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 11 1322 0.0083 1 1006 0.001 0 694 0 0 1008 0 0 978 0 12 5008 0.00239617 763110 chr7:45620649:G>A ADCY1 NM_021116:c.639+5868G>A INTRON1 Benign rs58525807 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 42 1322 0.0318 38 1006 0.0378 22 694 0.0317 0 1008 0 9 978 0.0092 111 5008 0.0221645 763111 chr7:45620656:T>C ADCY1 NM_021116:c.639+5875T>C INTRON1 Unknown significance rs757723467 This variant is a VUS because it does not have enough information. 763112 chr7:45620689:G>A ADCY1 NM_021116:c.639+5908G>A INTRON1 Unknown significance rs537971013 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681 763113 chr7:45620701:C>G ADCY1 NM_021116:c.639+5920C>G INTRON1 Benign rs12670925 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 127 1322 0.0961 313 1006 0.3111 198 694 0.2853 472 1008 0.4683 346 978 0.3538 1456 5008 0.290735 763114 chr7:45620706:T>G ADCY1 NM_021116:c.639+5925T>G INTRON1 Unknown significance rs577982154 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681 763115 chr7:45620713:A>G ADCY1 NM_021116:c.639+5932A>G INTRON1 Unknown significance rs369190555 This variant is a VUS because it does not have enough information. 763116 chr7:45620747:C>G ADCY1 NM_021116:c.639+5966C>G INTRON1 Unknown significance rs746188255 This variant is a VUS because it does not have enough information. 763117 chr7:45620761:C>G ADCY1 NM_021116:c.639+5980C>G INTRON1 Unknown significance rs547363273 This variant is a VUS because it does not have enough information. 763118 chr7:45620765:A>G ADCY1 NM_021116:c.639+5984A>G INTRON1 Unknown significance rs539013911 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681 763119 chr7:45620812:T>A ADCY1 NM_021116:c.639+6031T>A INTRON1 Unknown significance rs770399700 This variant is a VUS because it does not have enough information. 763120 chr7:45620816:T>C ADCY1 NM_021116:c.639+6035T>C INTRON1 Unknown significance rs554168582 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 763121 chr7:45620845:C>T ADCY1 NM_021116:c.639+6064C>T INTRON1 Unknown significance rs572778842 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 763122 chr7:45620880:->CTA ADCY1 NM_021116:c.639+6099_639+6100insCTA INTRON1 Unknown significance rs777482171 This variant is a VUS because it does not have enough information. 763123 chr7:45620884:C>G ADCY1 NM_021116:c.639+6103C>G INTRON1 Unknown significance rs375212641 This variant is a VUS because it does not have enough information. 763124 chr7:45620884:C>T ADCY1 NM_021116:c.639+6103C>T INTRON1 Unknown significance rs375212641 This variant is a VUS because it does not have enough information. 763125 chr7:45620891:C>T ADCY1 NM_021116:c.639+6110C>T INTRON1 Benign rs116118686 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 35 1322 0.0265 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 36 5008 0.0071885 763126 chr7:45620892:G>A ADCY1 NM_021116:c.639+6111G>A INTRON1 Unknown significance rs748712550 This variant is a VUS because it does not have enough information. 763127 chr7:45620931:TAGT>- ADCY1 NM_021116:c.639+6150_639+6153delTAGT INTRON1 Unknown significance rs571592698 This variant is a VUS because it does not have enough information. 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403 763128 chr7:45620936:A>C ADCY1 NM_021116:c.639+6155A>C INTRON1 Unknown significance rs139858012 This variant is a VUS because it does not have enough information. 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042 763129 chr7:45620960:C>T ADCY1 NM_021116:c.639+6179C>T INTRON1 Benign rs4724420 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 459 1322 0.3472 448 1006 0.4453 264 694 0.3804 508 1008 0.504 499 978 0.5102 2178 5008 0.434904 763130 chr7:45620969:C>T ADCY1 NM_021116:c.639+6188C>T INTRON1 Unknown significance rs768114089 This variant is a VUS because it does not have enough information. 763131 chr7:45620974:C>T ADCY1 NM_021116:c.639+6193C>T INTRON1 Unknown significance rs373398617 This variant is a VUS because it does not have enough information. 763132 chr7:45620987:C>A ADCY1 NM_021116:c.639+6206C>A INTRON1 Benign rs6975096 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 63 1322 0.0477 19 1006 0.0189 10 694 0.0144 26 1008 0.0258 36 978 0.0368 154 5008 0.0307508 763133 chr7:45621025:C>T ADCY1 NM_021116:c.639+6244C>T INTRON1 Unknown significance rs564987418 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 763134 chr7:45621031:C>T ADCY1 NM_021116:c.639+6250C>T INTRON1 Unknown significance rs532054069 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763135 chr7:45621045:T>C ADCY1 NM_021116:c.639+6264T>C INTRON1 Unknown significance rs745523593 This variant is a VUS because it does not have enough information. 763136 chr7:45621090:C>T ADCY1 NM_021116:c.639+6309C>T INTRON1 Unknown significance rs547001080 This variant is a VUS because it does not have enough information. 2 1322 0.0015 1 1006 0.001 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042 763137 chr7:45621091:G>A ADCY1 NM_021116:c.639+6310G>A INTRON1 Unknown significance rs189164930 This variant is a VUS because it does not have enough information. 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403 763138 chr7:45621097:G>T ADCY1 NM_021116:c.639+6316G>T INTRON1 Unknown significance rs761497962 This variant is a VUS because it does not have enough information. 763139 chr7:45621108:C>T ADCY1 NM_021116:c.639+6327C>T INTRON1 Unknown significance rs569987185 This variant is a VUS because it does not have enough information. 763140 chr7:45621117:G>A ADCY1 NM_021116:c.639+6336G>A INTRON1 Benign rs149857298 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 65 1322 0.0492 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 67 5008 0.0133786 763141 chr7:45621188:G>T ADCY1 NM_021116:c.639+6407G>T INTRON1 Unknown significance rs369660851 This variant is a VUS because it does not have enough information. 763142 chr7:45621233:C>T ADCY1 NM_021116:c.639+6452C>T INTRON1 Unknown significance rs762300876 This variant is a VUS because it does not have enough information. 763143 chr7:45621238:C>A ADCY1 NM_021116:c.639+6457C>A INTRON1 Unknown significance rs548047856 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681 763144 chr7:45621245:C>T ADCY1 NM_021116:c.639+6464C>T INTRON1 Unknown significance rs180684012 This variant is a VUS because it does not have enough information. 0 1322 0 2 1006 0.002 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361 763145 chr7:45621267:T>G ADCY1 NM_021116:c.639+6486T>G INTRON1 Unknown significance rs537229024 This variant is a VUS because it does not have enough information. 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403 763146 chr7:45621278:C>T ADCY1 NM_021116:c.639+6497C>T INTRON1 Benign rs79047754 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 2 1322 0.0015 46 1006 0.0457 28 694 0.0403 0 1008 0 3 978 0.0031 79 5008 0.0157748 763147 chr7:45621285:A>G ADCY1 NM_021116:c.639+6504A>G INTRON1 Unknown significance rs568392630 This variant is a VUS because it does not have enough information. 763148 chr7:45621319:G>A ADCY1 NM_021116:c.639+6538G>A INTRON1 Unknown significance rs766355112 This variant is a VUS because it does not have enough information. 763149 chr7:45621334:C>G ADCY1 NM_021116:c.639+6553C>G INTRON1 Unknown significance rs571722278 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763150 chr7:45621348:A>G ADCY1 NM_021116:c.639+6567A>G INTRON1 Unknown significance rs534616817 This variant is a VUS because it does not have enough information. 0 1322 0 1 1006 0.001 1 694 0.0014 0 1008 0 4 978 0.0041 6 5008 0.00119808 763151 chr7:45621361:A>G ADCY1 NM_021116:c.639+6580A>G INTRON1 Unknown significance rs554228178 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763152 chr7:45621371:A>G ADCY1 NM_021116:c.639+6590A>G INTRON1 Unknown significance rs146867738 This variant is a VUS because it does not have enough information. 6 1322 0.0045 0 1006 0 0 694 0 0 1008 0 0 978 0 6 5008 0.00119808 763153 chr7:45621375:T>C ADCY1 NM_021116:c.639+6594T>C INTRON1 Benign rs6957861 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 489 1322 0.3699 480 1006 0.4771 286 694 0.4121 670 1008 0.6647 603 978 0.6166 2528 5008 0.504792 763154 chr7:45621399:A>G ADCY1 NM_021116:c.639+6618A>G INTRON1 Unknown significance rs575809669 This variant is a VUS because it does not have enough information. 763155 chr7:45621411:C>A ADCY1 NM_021116:c.639+6630C>A INTRON1 Unknown significance rs764225388 This variant is a VUS because it does not have enough information. 763156 chr7:45621432:A>T ADCY1 NM_021116:c.639+6651A>T INTRON1 Unknown significance rs555277758 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 2 978 0.002 4 5008 0.000798722 763157 chr7:45621436:A>G ADCY1 NM_021116:c.639+6655A>G INTRON1 Unknown significance rs751667758 This variant is a VUS because it does not have enough information. 763158 chr7:45621438:A>G ADCY1 NM_021116:c.639+6657A>G INTRON1 Unknown significance rs576603239 This variant is a VUS because it does not have enough information. 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403 763159 chr7:45621444:->AC ADCY1 NM_021116:c.639+6663_639+6664insAC INTRON1 Unknown significance rs770525738 This variant is a VUS because it does not have enough information. 763160 chr7:45621444:AC>- ADCY1 NM_021116:c.639+6663_639+6664delAC INTRON1 Unknown significance rs769288579 This variant is a VUS because it does not have enough information. 763161 chr7:45621465:T>A ADCY1 NM_021116:c.639+6684T>A INTRON1 Unknown significance rs543989873 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 2 5008 0.000399361 763162 chr7:45621467:C>G ADCY1 NM_021116:c.639+6686C>G INTRON1 Benign rs117687736 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 4 1322 0.003 28 1006 0.0278 5 694 0.0072 10 1008 0.0099 101 978 0.1033 148 5008 0.0295527 763163 chr7:45621467:C>T ADCY1 NM_021116:c.639+6686C>T INTRON1 Benign rs117687736 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 8 1322 0.0061 0 1006 0 0 694 0 0 1008 0 0 978 0 8 5008 0.00159744 763164 chr7:45621471:C>T ADCY1 NM_021116:c.639+6690C>T INTRON1 Unknown significance rs781267519 This variant is a VUS because it does not have enough information. 763165 chr7:45621479:T>C ADCY1 NM_021116:c.639+6698T>C INTRON1 Benign rs6958039 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 490 1322 0.3707 480 1006 0.4771 286 694 0.4121 670 1008 0.6647 603 978 0.6166 2529 5008 0.504992 763166 chr7:45621486:A>G ADCY1 NM_021116:c.639+6705A>G INTRON1 Unknown significance rs558940399 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681 763167 chr7:45621517:A>- ADCY1 NM_021116:c.639+6736delA INTRON1 Unknown significance rs776680651 This variant is a VUS because it does not have enough information. 763168 chr7:45621523:G>C ADCY1 NM_021116:c.639+6742G>C INTRON1 Unknown significance rs761831267 This variant is a VUS because it does not have enough information. 763169 chr7:45621527:G>A ADCY1 NM_021116:c.639+6746G>A INTRON1 Benign rs117978250 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. 0 1322 0 1 1006 0.001 15 694 0.0216 125 1008 0.124 34 978 0.0348 175 5008 0.0349441 763170 chr7:45621534:A>G ADCY1 NM_021116:c.639+6753A>G INTRON1 Unknown significance rs541750766 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763171 chr7:45621587:A>G ADCY1 NM_021116:c.639+6806A>G INTRON1 Unknown significance rs563596346 This variant is a VUS because it does not have enough information. 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681 763172 chr7:45621593:G>A ADCY1 NM_021116:c.639+6812G>A INTRON1 Unknown significance rs530675052 This variant is a VUS because it does not have enough information. 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 763173 chr7:45621607:A>T ADCY1 NM_021116:c.639+6826A>T INTRON1 Unknown significance rs780640094 This variant is a VUS because it does not have enough information. 763174 chr7:45621618:C>T ADCY1 NM_021116:c.639+6837C>T INTRON1 Unknown significance rs573546503 This variant is a VUS because it does not have enough information. 763175 chr7:45621622:CT>- ADCY1 NM_021116:c.639+6841_639+6842delCT INTRON1 Unknown significance rs202181571 This variant is a VUS because it does not have enough information. 763176 chr7:45621624:CA>- ADCY1 NM_021116:c.639+6843_639+6844delCA INTRON1 Benign rs141367514 This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.