id variation gene hgvs_protein_change hgvs_nucleotide_change variantlocale pathogenicity disease pubmed_id dbsnp summary_insilico summary_frequency summary_published comments lrt_omega phylop_score phylop_pred sift_score sift_pred polyphen2_score polyphen2_pred lrt_score lrt_pred mutationtaster_score mutationtaster_pred gerp_nr gerp_rs gerp_pred evs_ea_ac evs_ea_an evs_ea_af evs_aa_ac evs_aa_an evs_aa_af evs_all_ac evs_all_an evs_all_af otoscope_aj_ac otoscope_aj_an otoscope_aj_af otoscope_co_ac otoscope_co_an otoscope_co_af otoscope_us_ac otoscope_us_an otoscope_us_af otoscope_jp_ac otoscope_jp_an otoscope_jp_af otoscope_es_ac otoscope_es_an otoscope_es_af otoscope_tr_ac otoscope_tr_an otoscope_tr_af otoscope_all_ac otoscope_all_an otoscope_all_af tg_afr_ac tg_afr_an tg_afr_af tg_eur_ac tg_eur_an tg_eur_af tg_amr_ac tg_amr_an tg_amr_af tg_eas_ac tg_eas_an tg_eas_af tg_sas_ac tg_sas_an tg_sas_af tg_all_ac tg_all_an tg_all_af exac_afr_ac exac_afr_an exac_afr_af exac_amr_ac exac_amr_an exac_amr_af exac_eas_ac exac_eas_an exac_eas_af exac_fin_ac exac_fin_an exac_fin_af exac_nfe_ac exac_nfe_an exac_nfe_af exac_oth_ac exac_oth_ant exac_oth_af exac_sas_ac exac_sas_an exac_sas_af exac_all_ac exac_all_an exac_all_af
488386 "chr21:35819014:G>A" "KCNE1" "NM_001270405:c.*2529C>T" "THREE_PRIME_EXON" "Benign" "rs2834485" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 932 1322 0.705 670 1006 0.666 468 694 0.6744 692 1008 0.6865 624 978 0.638 3386 5008 0.676118
488387 "chr21:35819021:C>G" "KCNE1" "NM_001270405:c.*2522G>C" "THREE_PRIME_EXON" "Unknown significance" "rs373184377" "This variant is a VUS because it does not have enough information."
488388 "chr21:35819029:T>C" "KCNE1" "NM_001270405:c.*2514A>G" "THREE_PRIME_EXON" "Unknown significance" "rs552886835" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
488389 "chr21:35819035:T>C" "KCNE1" "NM_001270405:c.*2508A>G" "THREE_PRIME_EXON" "Unknown significance" "rs566164652" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488390 "chr21:35819063:T>C" "KCNE1" "NM_001270405:c.*2480A>G" "THREE_PRIME_EXON" "Benign" "rs3453" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 503 1322 0.3805 506 1006 0.503 305 694 0.4395 535 1008 0.5308 411 978 0.4202 2260 5008 0.451278
488391 "chr21:35819065:G>C" "KCNE1" "NM_001270405:c.*2478C>G" "THREE_PRIME_EXON" "Unknown significance" "rs554562103" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
488392 "chr21:35819082:T>C" "KCNE1" "NM_001270405:c.*2461A>G" "THREE_PRIME_EXON" "Benign" "rs13050198" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 64 1322 0.0484 20 1006 0.0199 13 694 0.0187 92 1008 0.0913 84 978 0.0859 273 5008 0.0545128
488393 "chr21:35819084:A>G" "KCNE1" "NM_001270405:c.*2459T>C" "THREE_PRIME_EXON" "Unknown significance" "rs778082466" "This variant is a VUS because it does not have enough information."
488394 "chr21:35819088:T>C" "KCNE1" "NM_001270405:c.*2455A>G" "THREE_PRIME_EXON" "Unknown significance" "rs543391377" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
488395 "chr21:35819130:A>T" "KCNE1" "NM_001270405:c.*2413T>A" "THREE_PRIME_EXON" "Unknown significance" "rs747442476" "This variant is a VUS because it does not have enough information."
488396 "chr21:35819150:G>A" "KCNE1" "NM_001270405:c.*2393C>T" "THREE_PRIME_EXON" "Unknown significance" "rs567630448" "This variant is a VUS because it does not have enough information."
488397 "chr21:35819195:T>C" "KCNE1" "NM_001270405:c.*2348A>G" "THREE_PRIME_EXON" "Unknown significance" "rs558859988" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 2 978 0.002 2 5008 0.000399361
488398 "chr21:35819213:G>A" "KCNE1" "NM_001270405:c.*2330C>T" "THREE_PRIME_EXON" "Unknown significance" "rs780840352" "This variant is a VUS because it does not have enough information."
488399 "chr21:35819214:G>C" "KCNE1" "NM_001270405:c.*2329C>G" "THREE_PRIME_EXON" "Unknown significance" "rs373970167" "This variant is a VUS because it does not have enough information."
488400 "chr21:35819223:C>A" "KCNE1" "NM_001270405:c.*2320G>T" "THREE_PRIME_EXON" "Unknown significance" "rs745512218" "This variant is a VUS because it does not have enough information."
488401 "chr21:35819224:C>T" "KCNE1" "NM_001270405:c.*2319G>A" "THREE_PRIME_EXON" "Unknown significance" "rs528498228" "This variant is a VUS because it does not have enough information."
488402 "chr21:35819225:C>G" "KCNE1" "NM_001270405:c.*2318G>C" "THREE_PRIME_EXON" "Unknown significance" "rs200481471" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
488403 "chr21:35819227:C>T" "KCNE1" "NM_001270405:c.*2316G>A" "THREE_PRIME_EXON" "Unknown significance" "rs769307001" "This variant is a VUS because it does not have enough information."
488404 "chr21:35819278:G>T" "KCNE1" "NM_001270405:c.*2265C>A" "THREE_PRIME_EXON" "Unknown significance" "rs774883610" "This variant is a VUS because it does not have enough information."
488405 "chr21:35819315:C>T" "KCNE1" "NM_001270405:c.*2228G>A" "THREE_PRIME_EXON" "Unknown significance" "rs547037510" "This variant is a VUS because it does not have enough information." 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042
488406 "chr21:35819324:G>C" "KCNE1" "NM_001270405:c.*2219C>G" "THREE_PRIME_EXON" "Unknown significance" "rs559643678" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488407 "chr21:35819349:A>G" "KCNE1" "NM_001270405:c.*2194T>C" "THREE_PRIME_EXON" "Unknown significance" "rs529806670" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 3 978 0.0031 3 5008 0.000599042
488408 "chr21:35819362:G>A" "KCNE1" "NM_001270405:c.*2181C>T" "THREE_PRIME_EXON" "Unknown significance" "rs541917662" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 3 978 0.0031 3 5008 0.000599042
488409 "chr21:35819363:G>T" "KCNE1" "NM_001270405:c.*2180C>A" "THREE_PRIME_EXON" "Unknown significance" "rs563350002" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
488410 "chr21:35819367:A>G" "KCNE1" "NM_001270405:c.*2176T>C" "THREE_PRIME_EXON" "Unknown significance" "rs184101371" "This variant is a VUS because it does not have enough information."
488411 "chr21:35819385:A>G" "KCNE1" "NM_001270405:c.*2158T>C" "THREE_PRIME_EXON" "Unknown significance" "rs72550282" "This variant is a VUS because it does not have enough information."
488412 "chr21:35819393:C>T" "KCNE1" "NM_001270405:c.*2150G>A" "THREE_PRIME_EXON" "Unknown significance" "rs530554373" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 3 978 0.0031 3 5008 0.000599042
488413 "chr21:35819420:C>T" "KCNE1" "NM_001270405:c.*2123G>A" "THREE_PRIME_EXON" "Benign" "rs41314793" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 41 1322 0.031 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 43 5008 0.00858626
488414 "chr21:35819421:G>A" "KCNE1" "NM_001270405:c.*2122C>T" "THREE_PRIME_EXON" "Unknown significance" "rs139127272" "This variant is a VUS because it does not have enough information." 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042
488415 "chr21:35819436:C>T" "KCNE1" "NM_001270405:c.*2107G>A" "THREE_PRIME_EXON" "Unknown significance" "rs149936106" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488416 "chr21:35819439:C>T" "KCNE1" "NM_001270405:c.*2104G>A" "THREE_PRIME_EXON" "Unknown significance" "rs78666054" "This variant is a VUS because it does not have enough information."
488417 "chr21:35819440:G>A" "KCNE1" "NM_001270405:c.*2103C>T" "THREE_PRIME_EXON" "Benign" "rs41312367" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 99 1322 0.0749 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 101 5008 0.0201677
488418 "chr21:35819445:A>G" "KCNE1" "NM_001270405:c.*2098T>C" "THREE_PRIME_EXON" "Benign" "rs41312993" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 2 1322 0.0015 26 1006 0.0258 12 694 0.0173 1 1008 0.001 13 978 0.0133 54 5008 0.0107827
488419 "chr21:35819459:->TC" "KCNE1" "NM_001270405:c.*2084_*2085insGA" "THREE_PRIME_EXON" "Benign" "rs149361968" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 35 1322 0.0265 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 37 5008 0.00738818
488420 "chr21:35819528:C>T" "KCNE1" "NM_001270405:c.*2015G>A" "THREE_PRIME_EXON" "Unknown significance" "rs536776823" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
488421 "chr21:35819529:A>G" "KCNE1" "NM_001270405:c.*2014T>C" "THREE_PRIME_EXON" "Unknown significance" "rs41314797" "This variant is a VUS because it does not have enough information."
488422 "chr21:35819536:A>G" "KCNE1" "NM_001270405:c.*2007T>C" "THREE_PRIME_EXON" "Benign" "rs2211696" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1322 1322 1 1006 1006 1 694 694 1 1008 1008 1 978 978 1 5008 5008 1
488423 "chr21:35819540:G>A" "KCNE1" "NM_001270405:c.*2003C>T" "THREE_PRIME_EXON" "Unknown significance" "rs569801707" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
488424 "chr21:35819542:C>T" "KCNE1" "NM_001270405:c.*2001G>A" "THREE_PRIME_EXON" "Unknown significance" "rs41314799" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488425 "chr21:35819543:G>A" "KCNE1" "NM_001270405:c.*2000C>T" "THREE_PRIME_EXON" "Benign" "rs544071641" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 0 1008 0 8 978 0.0082 8 5008 0.00159744
488426 "chr21:35819594:C>A" "KCNE1" "NM_001270405:c.*1949G>T" "THREE_PRIME_EXON" "Unknown significance" "rs577470074" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 3 694 0.0043 0 1008 0 0 978 0 3 5008 0.000599042
488427 "chr21:35819609:A>G" "KCNE1" "NM_001270405:c.*1934T>C" "THREE_PRIME_EXON" "Unknown significance" "rs534967226" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 3 1008 0.003 1 978 0.001 4 5008 0.000798722
488428 "chr21:35819622:G>A" "KCNE1" "NM_001270405:c.*1921C>T" "THREE_PRIME_EXON" "Unknown significance" "rs553552077" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488429 "chr21:35819651:G>T" "KCNE1" "NM_001270405:c.*1892C>A" "THREE_PRIME_EXON" "Unknown significance" "rs77014863" "This variant is a VUS because it does not have enough information."
488430 "chr21:35819662:->GAAAGTCTCACTA" "KCNE1" "NM_001270405:c.*1881_*1882insTAGTGAGACTTTC" "THREE_PRIME_EXON" "Benign" "rs528676590" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 0 1008 0 6 978 0.0061 6 5008 0.00119808
488431 "chr21:35819684:C>T" "KCNE1" "NM_001270405:c.*1859G>A" "THREE_PRIME_EXON" "Unknown significance" "rs754021039" "This variant is a VUS because it does not have enough information."
488432 "chr21:35819705:A>T" "KCNE1" "NM_001270405:c.*1838T>A" "THREE_PRIME_EXON" "Unknown significance" "rs41312369" "This variant is a VUS because it does not have enough information." 0 1322 0 3 1006 0.003 2 694 0.0029 0 1008 0 0 978 0 5 5008 0.000998403
488433 "chr21:35819712:G>A" "KCNE1" "NM_001270405:c.*1831C>T" "THREE_PRIME_EXON" "Unknown significance" "rs41314065" "This variant is a VUS because it does not have enough information."
488434 "chr21:35819720:C>T" "KCNE1" "NM_001270405:c.*1823G>A" "THREE_PRIME_EXON" "Unknown significance" "rs557127914" "This variant is a VUS because it does not have enough information."
488435 "chr21:35819728:T>C" "KCNE1" "NM_001270405:c.*1815A>G" "THREE_PRIME_EXON" "Benign" "rs57555550" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 28 1322 0.0212 0 1006 0 0 694 0 0 1008 0 0 978 0 28 5008 0.00559105
488436 "chr21:35819728:T>G" "KCNE1" "NM_001270405:c.*1815A>C" "THREE_PRIME_EXON" "Unknown significance" "rs57555550" "This variant is a VUS because it does not have enough information."
488437 "chr21:35819738:G>A" "KCNE1" "NM_001270405:c.*1805C>T" "THREE_PRIME_EXON" "Unknown significance" "rs569145291" "This variant is a VUS because it does not have enough information."
488438 "chr21:35819821:T>A" "KCNE1" "NM_001270405:c.*1722A>T" "THREE_PRIME_EXON" "Unknown significance" "rs752763249" "This variant is a VUS because it does not have enough information."
488439 "chr21:35819823:C>T" "KCNE1" "NM_001270405:c.*1720G>A" "THREE_PRIME_EXON" "Unknown significance" "rs563412373" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488440 "chr21:35819877:C>T" "KCNE1" "NM_001270405:c.*1666G>A" "THREE_PRIME_EXON" "Unknown significance" "rs181999033" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 3 1008 0.003 0 978 0 3 5008 0.000599042
488441 "chr21:35819893:T>C" "KCNE1" "NM_001270405:c.*1650A>G" "THREE_PRIME_EXON" "Unknown significance" "rs758904237" "This variant is a VUS because it does not have enough information."
488442 "chr21:35819897:G>A" "KCNE1" "NM_001270405:c.*1646C>T" "THREE_PRIME_EXON" "Unknown significance" "rs545816015" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488443 "chr21:35819907:T>C" "KCNE1" "NM_001270405:c.*1636A>G" "THREE_PRIME_EXON" "Unknown significance" "rs563883290" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488444 "chr21:35819915:G>T" "KCNE1" "NM_001270405:c.*1628C>A" "THREE_PRIME_EXON" "Unknown significance" "rs778313101" "This variant is a VUS because it does not have enough information."
488445 "chr21:35819929:A>C" "KCNE1" "NM_001270405:c.*1614T>G" "THREE_PRIME_EXON" "Unknown significance" "rs528400300" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488446 "chr21:35819956:C>G" "KCNE1" "NM_001270405:c.*1587G>C" "THREE_PRIME_EXON" "Unknown significance" "rs546552784" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488447 "chr21:35819969:G>A" "KCNE1" "NM_001270405:c.*1574C>T" "THREE_PRIME_EXON" "Unknown significance" "rs561997378" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488448 "chr21:35819974:C>T" "KCNE1" "NM_001270405:c.*1569G>A" "THREE_PRIME_EXON" "Unknown significance" "rs752075590" "This variant is a VUS because it does not have enough information."
488449 "chr21:35819990:G>C" "KCNE1" "NM_001270405:c.*1553C>G" "THREE_PRIME_EXON" "Benign" "rs375872606" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 17 1322 0.0129 0 1006 0 0 694 0 0 1008 0 0 978 0 17 5008 0.00339457
488450 "chr21:35819993:C>A" "KCNE1" "NM_001270405:c.*1550G>T" "THREE_PRIME_EXON" "Unknown significance" "rs183867689" "This variant is a VUS because it does not have enough information."
488451 "chr21:35819996:->C" "KCNE1" "NM_001270405:c.*1547_*1548insG" "THREE_PRIME_EXON" "Benign" "rs11373310" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1321 1322 0.9992 1006 1006 1 694 694 1 1008 1008 1 977 978 0.999 5006 5008 0.999601
488452 "chr21:35819999:T>C" "KCNE1" "NM_001270405:c.*1544A>G" "THREE_PRIME_EXON" "Unknown significance" "rs186289801" "This variant is a VUS because it does not have enough information."
488453 "chr21:35820003:G>C" "KCNE1" "NM_001270405:c.*1540C>G" "THREE_PRIME_EXON" "Unknown significance" "rs550354116" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 1 694 0.0014 0 1008 0 0 978 0 2 5008 0.000399361
488454 "chr21:35820004:G>T" "KCNE1" "NM_001270405:c.*1539C>A" "THREE_PRIME_EXON" "Unknown significance" "rs41314801" "This variant is a VUS because it does not have enough information."
488455 "chr21:35820050:G>A" "KCNE1" "NM_001270405:c.*1493C>T" "THREE_PRIME_EXON" "Unknown significance" "rs757551504" "This variant is a VUS because it does not have enough information."
488456 "chr21:35820088:T>C" "KCNE1" "NM_001270405:c.*1455A>G" "THREE_PRIME_EXON" "Unknown significance" "rs746772688" "This variant is a VUS because it does not have enough information."
488457 "chr21:35820188:C>T" "KCNE1" "NM_001270405:c.*1355G>A" "THREE_PRIME_EXON" "Unknown significance" "rs569863063" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361
488458 "chr21:35820205:G>A" "KCNE1" "NM_001270405:c.*1338C>T" "THREE_PRIME_EXON" "Benign" "rs74508995" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 8 1006 0.008 1 694 0.0014 0 1008 0 1 978 0.001 10 5008 0.00199681
488459 "chr21:35820212:G>A" "KCNE1" "NM_001270405:c.*1331C>T" "THREE_PRIME_EXON" "Unknown significance" "rs745475336" "This variant is a VUS because it does not have enough information."
488460 "chr21:35820221:T>-" "KCNE1" "NM_001270405:c.*1322delA" "THREE_PRIME_EXON" "Unknown significance" "rs780114909" "This variant is a VUS because it does not have enough information."
488461 "chr21:35820221:T>C" "KCNE1" "NM_001270405:c.*1322A>G" "THREE_PRIME_EXON" "Benign" "rs11700621" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 311 1322 0.2352 57 1006 0.0567 24 694 0.0346 19 1008 0.0188 44 978 0.045 455 5008 0.0908546
488462 "chr21:35820254:G>A" "KCNE1" "NM_001270405:c.*1289C>T" "THREE_PRIME_EXON" "Unknown significance" "rs570723178" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
488463 "chr21:35820265:C>T" "KCNE1" "NM_001270405:c.*1278G>A" "THREE_PRIME_EXON" "Unknown significance" "rs534995446" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
488464 "chr21:35820266:G>A" "KCNE1" "NM_001270405:c.*1277C>T" "THREE_PRIME_EXON" "Unknown significance" "rs186537411" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
488465 "chr21:35820275:T>C" "KCNE1" "NM_001270405:c.*1268A>G" "THREE_PRIME_EXON" "Unknown significance" "rs539859024" "This variant is a VUS because it does not have enough information."
488466 "chr21:35820306:C>G" "KCNE1" "NM_001270405:c.*1237G>C" "THREE_PRIME_EXON" "Unknown significance" "rs748870790" "This variant is a VUS because it does not have enough information."
488467 "chr21:35820314:CGGC>-" "KCNE1" "NM_001270405:c.*1229_*1234delGCCG" "THREE_PRIME_EXON" "Benign" "rs551512090" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 5 1006 0.005 3 694 0.0043 1 1008 0.001 0 978 0 9 5008 0.00179712
488468 "chr21:35820314:C>T" "KCNE1" "NM_001270405:c.*1229G>A" "THREE_PRIME_EXON" "Unknown significance" "rs143524624" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488469 "chr21:35820324:T>C" "KCNE1" "NM_001270405:c.*1219A>G" "THREE_PRIME_EXON" "Benign" "rs11909074" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 514 1322 0.3888 536 1006 0.5328 362 694 0.5216 578 1008 0.5734 482 978 0.4928 2472 5008 0.49361
488470 "chr21:35820329:C>T" "KCNE1" "NM_001270405:c.*1214G>A" "THREE_PRIME_EXON" "Unknown significance" "rs534297559" "This variant is a VUS because it does not have enough information."
488471 "chr21:35820332:A>G" "KCNE1" "NM_001270405:c.*1211T>C" "THREE_PRIME_EXON" "Unknown significance" "rs774369065" "This variant is a VUS because it does not have enough information."
488472 "chr21:35820371:C>G" "KCNE1" "NM_001270405:c.*1172G>C" "THREE_PRIME_EXON" "Unknown significance" "rs552894653" "This variant is a VUS because it does not have enough information."
488473 "chr21:35820404:C>A" "KCNE1" "NM_001270405:c.*1139G>T" "THREE_PRIME_EXON" "Unknown significance" "rs190218314" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
488474 "chr21:35820445:A>G" "KCNE1" "NM_001270405:c.*1098T>C" "THREE_PRIME_EXON" "Unknown significance" "rs74534917" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
488475 "chr21:35820465:C>T" "KCNE1" "NM_001270405:c.*1078G>A" "THREE_PRIME_EXON" "Unknown significance" "rs41312995" "This variant is a VUS because it does not have enough information."
488476 "chr21:35820475:T>G" "KCNE1" "NM_001270405:c.*1068A>C" "THREE_PRIME_EXON" "Benign" "rs41314803" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 171 1322 0.1293 2 1006 0.002 7 694 0.0101 0 1008 0 0 978 0 180 5008 0.0359425
488477 "chr21:35820503:G>A" "KCNE1" "NM_001270405:c.*1040C>T" "THREE_PRIME_EXON" "Unknown significance" "rs772932255" "This variant is a VUS because it does not have enough information."
488478 "chr21:35820523:C>T" "KCNE1" "NM_001270405:c.*1020G>A" "THREE_PRIME_EXON" "Unknown significance" "rs577011231" "This variant is a VUS because it does not have enough information."
488479 "chr21:35820527:C>T" "KCNE1" "NM_001270405:c.*1016G>A" "THREE_PRIME_EXON" "Unknown significance" "rs759775398" "This variant is a VUS because it does not have enough information."
488480 "chr21:35820561:G>A" "KCNE1" "NM_001270405:c.*982C>T" "THREE_PRIME_EXON" "Unknown significance" "rs765446084" "This variant is a VUS because it does not have enough information."
488481 "chr21:35820583:G>A" "KCNE1" "NM_001270405:c.*960C>T" "THREE_PRIME_EXON" "Unknown significance" "rs544365018" "This variant is a VUS because it does not have enough information."
488482 "chr21:35820597:C>-" "KCNE1" "NM_001270405:c.*946delG" "THREE_PRIME_EXON" "Benign" "rs142762112" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 2 1322 0.0015 29 1006 0.0288 57 694 0.0821 40 1008 0.0397 76 978 0.0777 204 5008 0.0407348
488483 "chr21:35820598:C>A" "KCNE1" "NM_001270405:c.*945G>T" "THREE_PRIME_EXON" "Unknown significance" "rs762963570" "This variant is a VUS because it does not have enough information."
488484 "chr21:35820609:C>T" "KCNE1" "NM_001270405:c.*934G>A" "THREE_PRIME_EXON" "Unknown significance" "rs372597772" "This variant is a VUS because it does not have enough information."
488485 "chr21:35820620:C>T" "KCNE1" "NM_001270405:c.*923G>A" "THREE_PRIME_EXON" "Unknown significance" "rs182050647" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 3 1008 0.003 0 978 0 3 5008 0.000599042
488486 "chr21:35820646:C>G" "KCNE1" "NM_001270405:c.*897G>C" "THREE_PRIME_EXON" "Unknown significance" "rs77365012" "This variant is a VUS because it does not have enough information."
488487 "chr21:35820651:G>-" "KCNE1" "NM_001270405:c.*892delC" "THREE_PRIME_EXON" "Unknown significance" "rs34259791" "This variant is a VUS because it does not have enough information."
488488 "chr21:35820658:->T" "KCNE1" "NM_001270405:c.*885_*886insA" "THREE_PRIME_EXON" "Unknown significance" "rs570358822" "This variant is a VUS because it does not have enough information." 6 1322 0.0045 0 1006 0 0 694 0 0 1008 0 0 978 0 6 5008 0.00119808
488489 "chr21:35820674:CTCAG>-" "KCNE1" "NM_001270405:c.*869_*875delCTGAG" "THREE_PRIME_EXON" "Unknown significance" "rs775242276" "This variant is a VUS because it does not have enough information."
488490 "chr21:35820674:C>T" "KCNE1" "NM_001270405:c.*869G>A" "THREE_PRIME_EXON" "Unknown significance" "rs764163919" "This variant is a VUS because it does not have enough information."
488491 "chr21:35820691:C>T" "KCNE1" "NM_001270405:c.*852G>A" "THREE_PRIME_EXON" "Unknown significance" "rs752022253" "This variant is a VUS because it does not have enough information."
488492 "chr21:35820707:T>C" "KCNE1" "NM_001270405:c.*836A>G" "THREE_PRIME_EXON" "Unknown significance" "rs572781670" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
488493 "chr21:35820710:G>A" "KCNE1" "NM_001270405:c.*833C>T" "THREE_PRIME_EXON" "Unknown significance" "rs186384068" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
488494 "chr21:35820726:T>C" "KCNE1" "NM_001270405:c.*817A>G" "THREE_PRIME_EXON" "Unknown significance" "rs75375964" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 4 1006 0.004 3 694 0.0043 0 1008 0 0 978 0 9 5008 0.00179712
488495 "chr21:35820736:A>G" "KCNE1" "NM_001270405:c.*807T>C" "THREE_PRIME_EXON" "Unknown significance" "rs563756790" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
488496 "chr21:35820739:G>T" "KCNE1" "NM_001270405:c.*804C>A" "THREE_PRIME_EXON" "Unknown significance" "rs767900727" "This variant is a VUS because it does not have enough information."
488497 "chr21:35820801:C>T" "KCNE1" "NM_001270405:c.*742G>A" "THREE_PRIME_EXON" "Unknown significance" "rs750791574" "This variant is a VUS because it does not have enough information."
488498 "chr21:35820812:G>A" "KCNE1" "NM_001270405:c.*731C>T" "THREE_PRIME_EXON" "Unknown significance" "rs755785718" "This variant is a VUS because it does not have enough information."
488499 "chr21:35820861:C>A" "KCNE1" "NM_001270405:c.*682G>T" "THREE_PRIME_EXON" "Unknown significance" "rs550366224" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488500 "chr21:35820863:G>C" "KCNE1" "NM_001270405:c.*680C>G" "THREE_PRIME_EXON" "Unknown significance" "rs146664227" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
488501 "chr21:35820883:T>C" "KCNE1" "NM_001270405:c.*660A>G" "THREE_PRIME_EXON" "Unknown significance" "rs779628968" "This variant is a VUS because it does not have enough information."
488502 "chr21:35820949:G>A" "KCNE1" "NM_001270405:c.*594C>T" "THREE_PRIME_EXON" "Unknown significance" "rs748958636" "This variant is a VUS because it does not have enough information."
488503 "chr21:35820956:A>G" "KCNE1" "NM_001270405:c.*587T>C" "THREE_PRIME_EXON" "Unknown significance" "rs530927611" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488504 "chr21:35820965:A>G" "KCNE1" "NM_001270405:c.*578T>C" "THREE_PRIME_EXON" "Benign" "rs16991703" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 370 1322 0.2799 56 1006 0.0557 25 694 0.036 19 1008 0.0188 56 978 0.0573 526 5008 0.105032
488505 "chr21:35820990:T>C" "KCNE1" "NM_001270405:c.*553A>G" "THREE_PRIME_EXON" "Benign" "rs570907779" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 0 1008 0 7 978 0.0072 7 5008 0.00139776
488506 "chr21:35821046:C>T" "KCNE1" "NM_001270405:c.*497G>A" "THREE_PRIME_EXON" "Unknown significance" "rs182169396" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
488507 "chr21:35821049:C>T" "KCNE1" "NM_001270405:c.*494G>A" "THREE_PRIME_EXON" "Unknown significance" "rs546969097" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
488508 "chr21:35821050:G>A" "KCNE1" "NM_001270405:c.*493C>T" "THREE_PRIME_EXON" "Unknown significance" "rs77190660" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 1 694 0.0014 0 1008 0 0 978 0 2 5008 0.000399361
488509 "chr21:35821053:C>G" "KCNE1" "NM_001270405:c.*490G>C" "THREE_PRIME_EXON" "Benign" "rs41314067" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 308 1322 0.233 57 1006 0.0567 24 694 0.0346 19 1008 0.0188 44 978 0.045 452 5008 0.0902556
488510 "chr21:35821056:G>A" "KCNE1" "NM_001270405:c.*487C>T" "THREE_PRIME_EXON" "Unknown significance" "rs557601529" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
488511 "chr21:35821078:G>C" "KCNE1" "NM_001270405:c.*465C>G" "THREE_PRIME_EXON" "Unknown significance" "rs569443538" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
488512 "chr21:35821087:G>A" "KCNE1" "NM_001270405:c.*456C>T" "THREE_PRIME_EXON" "Benign" "rs2070356" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 499 1322 0.3775 503 1006 0.5 304 694 0.438 533 1008 0.5288 405 978 0.4141 2244 5008 0.448083
488513 "chr21:35821100:C>G" "KCNE1" "NM_001270405:c.*443G>C" "THREE_PRIME_EXON" "Unknown significance" "rs557604590" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
488514 "chr21:35821117:C>T" "KCNE1" "NM_001270405:c.*426G>A" "THREE_PRIME_EXON" "Unknown significance" "rs79859743" "This variant is a VUS because it does not have enough information."
488515 "chr21:35821127:A>C" "KCNE1" "NM_001270405:c.*416T>G" "THREE_PRIME_EXON" "Unknown significance" "rs186623682" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488516 "chr21:35821156:A>G" "KCNE1" "NM_001270405:c.*387T>C" "THREE_PRIME_EXON" "Unknown significance" "rs375219821" "This variant is a VUS because it does not have enough information."
488517 "chr21:35821167:C>T" "KCNE1" "NM_001270405:c.*376G>A" "THREE_PRIME_EXON" "Unknown significance" "rs539897251" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
488518 "chr21:35821170:T>C" "KCNE1" "NM_001270405:c.*373A>G" "THREE_PRIME_EXON" "Unknown significance" "rs41314805" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
488519 "chr21:35821186:->C" "KCNE1" "NM_001270405:c.*357_*358insG" "THREE_PRIME_EXON" "Unknown significance" "rs34256415" "This variant is a VUS because it does not have enough information."
488520 "chr21:35821209:A>G" "KCNE1" "NM_001270405:c.*334T>C" "THREE_PRIME_EXON" "Unknown significance" "rs573607715" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488521 "chr21:35821251:T>A" "KCNE1" "NM_001270405:c.*292A>T" "THREE_PRIME_EXON" "Unknown significance" "rs369248363" "This variant is a VUS because it does not have enough information."
488522 "chr21:35821275:G>A" "KCNE1" "NM_001270405:c.*268C>T" "THREE_PRIME_EXON" "Benign" "rs41314807" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 62 1322 0.0469 1 1006 0.001 1 694 0.0014 0 1008 0 0 978 0 64 5008 0.0127796
488523 "chr21:35821283:T>G" "KCNE1" "NM_001270405:c.*260A>C" "THREE_PRIME_EXON" "Unknown significance" "rs41312371" "This variant is a VUS because it does not have enough information."
488524 "chr21:35821347:G>C" "KCNE1" "NM_001270405:c.*196C>G" "THREE_PRIME_EXON" "Unknown significance" "rs76568182" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488525 "chr21:35821358:A>C" "KCNE1" "NM_001270405:c.*185T>G" "THREE_PRIME_EXON" "Unknown significance" "rs770775585" "This variant is a VUS because it does not have enough information."
488526 "chr21:35821367:C>A" "KCNE1" "NM_001270405:c.*176G>T" "THREE_PRIME_EXON" "Benign" "rs77924638" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 9 1322 0.0068 0 1006 0 0 694 0 0 1008 0 0 978 0 9 5008 0.00179712
488527 "chr21:35821375:C>T" "KCNE1" "NM_001270405:c.*168G>A" "THREE_PRIME_EXON" "Unknown significance" "rs545176903" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488528 "chr21:35821376:G>T" "KCNE1" "NM_001270405:c.*167C>A" "THREE_PRIME_EXON" "Benign" "rs41314069" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 6 1008 0.006 0 978 0 6 5008 0.00119808
488529 "chr21:35821383:T>C" "KCNE1" "NM_001270405:c.*160A>G" "THREE_PRIME_EXON" "Unknown significance" "rs191019553" "This variant is a VUS because it does not have enough information." 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042
488530 "chr21:35821393:G>A" "KCNE1" "NM_001270405:c.*150C>T" "THREE_PRIME_EXON" "Unknown significance" "rs145330135" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
488531 "chr21:35821411:T>C" "KCNE1" "NM_001270405:c.*132A>G" "THREE_PRIME_EXON" "Benign" "rs41314071" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 307 1322 0.2322 57 1006 0.0567 24 694 0.0346 19 1008 0.0188 44 978 0.045 451 5008 0.0900559
488532 "chr21:35821415:C>-" "KCNE1" "NM_001270405:c.*128delG" "THREE_PRIME_EXON" "Benign" "rs549011886" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 0 1008 0 5 978 0.0051 5 5008 0.000998403
488533 "chr21:35821415:->C" "KCNE1" "NM_001270405:c.*128_*129insG" "THREE_PRIME_EXON" "Unknown significance" "rs78790696" "This variant is a VUS because it does not have enough information."
488534 "chr21:35821419:T>C" "KCNE1" "NM_001270405:c.*124A>G" "THREE_PRIME_EXON" "Benign" "rs2070357" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 324 1322 0.2451 502 1006 0.499 297 694 0.428 535 1008 0.5308 406 978 0.4151 2064 5008 0.412141
488535 "chr21:35821429:C>A" "KCNE1" "NM_001270405:c.*114G>T" "THREE_PRIME_EXON" "Unknown significance" "rs757162517" "This variant is a VUS because it does not have enough information."
488536 "chr21:35821452:G>-" "KCNE1" "NM_001270405:c.*91delC" "THREE_PRIME_EXON" "Unknown significance" "rs748419617" "This variant is a VUS because it does not have enough information."
488537 "chr21:35821463:C>A" "KCNE1" "NM_001270405:c.*80G>T" "THREE_PRIME_EXON" "Unknown significance" "rs373302449" "This variant is a VUS because it does not have enough information."
488538 "chr21:35821472:G>A" "KCNE1" "NM_001270405:c.*71C>T" "THREE_PRIME_EXON" "Unknown significance" "rs749799898" "This variant is a VUS because it does not have enough information."
488539 "chr21:35821494:A>C" "KCNE1" "NM_001270405:c.*49T>G" "THREE_PRIME_EXON" "Unknown significance" "rs763362235" "This variant is a VUS because it does not have enough information."
488540 "chr21:35821509:G>A" "KCNE1" "NM_001270405:c.*34C>T" "THREE_PRIME_EXON" "Unknown significance" "rs771525839" "This variant is a VUS because it does not have enough information." 0 8894 0 0 11496 0 0 8546 0 0 6614 0 0 63224 0 0 856 0 1 14212 0.0000703631 1 113842 0.0000087841
488541 "chr21:35821513:G>C" "KCNE1" "NM_001270405:c.*30C>G" "THREE_PRIME_EXON" "Unknown significance" "rs150963475" "This variant is a VUS because it does not have enough information." 6 8584 0.000698975 0 4390 0 6 12974 0.000462463 0 1322 0 2 1006 0.002 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361 0 8916 0 0 11502 0 0 8548 0 0 6614 0 41 63344 0.000647259 0 856 0 0 14352 0 41 114132 0.000359233
488542 "chr21:35821516:G>A" "KCNE1" "NM_001270405:c.*27C>T" "THREE_PRIME_EXON" "Unknown significance" "rs377377233" "This variant is a VUS because it does not have enough information." 0 8592 0 1 4392 0.000227687 1 12984 0.0000770179
488543 "chr21:35821549:G>T" "KCNE1" "NM_001270405:p.Ser128Ser" "NM_001270405:c.384C>A" "EXON3" "Unknown significance" "rs759950872" "This variant is a VUS because it does not have enough information." 1 9384 0.000106564 0 11516 0 0 8568 0 0 6614 0 0 64354 0 0 880 0 0 15712 0 1 117028 0.00000854496
488544 "chr21:35821554:G>T" "KCNE1" "NM_001270405:p.Pro127Thr" "NM_001270405:c.379C>A" "EXON3" "Pathogenic" "Long QT syndrome" "15051636|10973849|24912595|25037568" "rs199473647" "Pathogenicity is based on ClinVar submissions and the literature provided in PubMed." 0.029 "N" "0.01;.;0.01;.;0.01;0.01;0.01;0.01" "D;.;D;.;D;D;D;D" "0.024" "B" 0.499451 "N" 1 "D;N;N;N;N;" "0.671" "C"
488545 "chr21:35821558:C>T" "KCNE1" "NM_001270405:p.Thr125Thr" "NM_001270405:c.375G>A" "EXON3" "Unknown significance" "rs767686634" "This variant is a VUS because it does not have enough information." 0 9606 0 1 11524 0.0000867754 0 8570 0 0 6614 0 4 64702 0.0000618219 0 890 0 0 15912 0 5 117818 0.0000424383
488546 "chr21:35821559:G>A" "KCNE1" "NM_001270405:p.Thr125Met" "NM_001270405:c.374C>T" "EXON3" "Pathogenic" "Long QT syndrome" "23994779|19716085|24033266|25637381" "rs142511345" "Pathogenicity is based on ClinVar submissions and the literature provided in PubMed." -2.285 "N" "0.125;.;0.125;.;0.125;0.125;0.125;0.125" "T;.;T;.;T;T;T;T" "0.01" "B" 0.216691 "N" 1 "N" "-9.88" "N" 0 8600 0 3 4406 0.00068089 3 13006 0.000230663 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361 9 9664 0.000931291 3 11526 0.000260281 3 8570 0.000350058 0 6614 0 0 64782 0 0 892 0 5 16018 0.000312149 20 118066 0.000169397
488547 "chr21:35821582:T>A" "KCNE1" "NM_001270405:p.Gln117His" "NM_001270405:c.351A>T" "EXON3" "Likely benign" "rs760939855" "Pathogenicity is based on prediction data only. 0 out of 6 predictions were pathogenic." -0.428 "N" "0.061;.;0.061;.;0.061;0.061;0.061;0.061" "T;.;T;.;T;T;T;T" "0.001" "B" 0.036642 "N" 0.988824 "N" "-9.88" "N"
488548 "chr21:35821584:G>A" "KCNE1" "NM_001270405:p.Gln117Stop" "NM_001270405:c.349C>T" "EXON3" "Pathogenic" "Long QT syndrome" "19716085" "rs764130990" "Pathogenicity is based on the literature provided in PubMed." 0.902 "N" 0.036642 "N" 0.998316 "D" "4.05" "C" 0 10144 0 1 11552 0.0000865651 0 8586 0 0 6614 0 0 65668 0 0 898 0 0 16402 0 1 119864 0.00000834279
488549 "chr21:35821593:C>T" "KCNE1" "NM_001270405:p.Ala114Thr" "NM_001270405:c.340G>A" "EXON3" "Likely benign" "rs754020878" "Pathogenicity is based on prediction data only. 2 out of 6 predictions were pathogenic." 0.807 "N" "0.088;.;0.088;.;0.088;0.088;0.088;0.088" "T;.;T;.;T;T;T;T" "0.27" "B" 0.005601 "N" 0.985326 "D" "3.1" "C" 0 10188 0 0 11552 0 0 8592 0 0 6614 0 1 65804 0.0000151966 0 900 0 0 16460 0 1 120110 0.0000083257
488550 "chr21:35821594:C>T" "KCNE1" "NM_001270405:p.Leu113Leu" "NM_001270405:c.339G>A" "EXON3" "Unknown significance" "rs376829542" "This variant is a VUS because it does not have enough information." 0 8600 0 1 4406 0.000226963 1 13006 0.0000768876 2 10192 0.000196232 0 11552 0 0 8594 0 0 6614 0 0 65812 0 0 900 0 0 16464 0 2 120128 0.0000166489
488551 "chr21:35821596:G>T" "KCNE1" "NM_001270405:p.Leu113Met" "NM_001270405:c.337C>A" "EXON3" "Likely benign" "rs547023570" "Pathogenicity is based on prediction data only. 1 out of 6 predictions were pathogenic." -0.017 "N" "0.116;.;0.116;.;0.116;0.116;0.116;0.116" "T;.;T;.;T;T;T;T" "0.014" "B" 0.373538 "N" 0.998263 "N" "1.85" "C"
488552 "chr21:35821608:C>T" "KCNE1" "NM_001270405:p.Val109Ile" "NM_001270405:c.325G>A" "EXON3" "Pathogenic" "Long QT syndrome" "11692163|22378279|25637381|25037568" "rs77442996" "Pathogenicity is based on the literature provided in PubMed." -0.841 "N" "1.0;.;1.0;.;1.0;1.0;1.0;1.0" "T;.;T;.;T;T;T;T" "0.0" "B" 0.092946 "N" 1 "N" "-4.63" "N" 1 8600 0.000116279 1 4406 0.000226963 2 13006 0.000153775 6 10214 0.000587429 0 11556 0 0 8610 0 1 6614 0.000151194 2 65984 0.0000303104 1 902 0.00110865 8 16498 0.000484907 18 120378 0.000149529
488553 "chr21:35821609:G>A" "KCNE1" "NM_001270405:p.Val108Val" "NM_001270405:c.324C>T" "EXON3" "Unknown significance" "rs200684060" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 0 10226 0 0 11556 0 1 8610 0.000116144 0 6614 0 2 66006 0.0000303003 0 902 0 0 16500 0 3 120414 0.000024914
488554 "chr21:35821615:G>T" "KCNE1" "NM_001270405:p.Cys106Stop" "NM_001270405:c.318C>A" "EXON3" "Unknown significance" "rs17853625" "This variant is a VUS because it does not have enough information." -1.049 "N" 0.000016 "D" 1 "D" "-4.73" "N"
488555 "chr21:35821618:C>T" "KCNE1" "NM_001270405:p.Ser105Ser" "NM_001270405:c.315G>A" "EXON3" "Unknown significance" "rs563859144" "This variant is a VUS because it does not have enough information." 0 10262 0 0 11556 0 0 8616 0 0 6614 0 2 66144 0.0000302371 0 906 0 1 16506 0.000060584 3 120604 0.0000248748
488556 "chr21:35821619:G>A" "KCNE1" "NM_001270405:p.Ser105Leu" "NM_001270405:c.314C>T" "EXON3" "Likely benign" "rs780041404" "Pathogenicity is based on prediction data only. 1 out of 6 predictions were pathogenic." 0.902 "N" "0.261;.;0.261;.;0.261;0.261;0.261;0.261" "T;.;T;.;T;T;T;T" "0.0" "B" 0.095329 "N" 1 "N" "3.01" "C" 1 10272 0.000097352 0 11556 0 0 8616 0 0 6614 0 1 66168 0.000015113 1 906 0.00110375 8 16506 0.000484672 11 120638 0.0000911819
488557 "chr21:35821621:C>T" "KCNE1" "NM_001270405:p.Arg104Arg" "NM_001270405:c.312G>A" "EXON3" "Unknown significance" "rs746628151" "This variant is a VUS because it does not have enough information." 1 10278 0.0000972952 0 11556 0 0 8618 0 0 6614 0 0 66194 0 0 906 0 0 16506 0 1 120672 0.00000828693
488558 "chr21:35821635:G>A" "KCNE1" "NM_001270405:p.Leu100Leu" "NM_001270405:c.298C>T" "EXON3" "Unknown significance" "rs140643047" "This variant is a VUS because it does not have enough information." 0 8600 0 1 4406 0.000226963 1 13006 0.0000768876 1 10308 0.000097012 0 11564 0 0 8622 0 0 6614 0 0 66370 0 0 906 0 0 16508 0 1 120892 0.00000827185
488559 "chr21:35821636:G>A" "KCNE1" "NM_001270405:p.Val99Val" "NM_001270405:c.297C>T" "EXON3" "Unknown significance" "rs780553669" "This variant is a VUS because it does not have enough information." 0 10312 0 0 11564 0 0 8622 0 0 6614 0 0 66374 0 0 906 0 1 16508 0.0000605767 1 120900 0.0000082713
488560 "chr21:35821638:C>T" "KCNE1" "NM_001270405:p.Val99Ile" "NM_001270405:c.295G>A" "EXON3" "Likely benign" "rs774463420" "Pathogenicity is based on prediction data only. 0 out of 6 predictions were pathogenic." 0.807 "N" "0.248;.;0.248;.;0.248;0.248;0.248;0.248" "T;.;T;.;T;T;T;T" "0.0" "B" 0.587083 "N" 1 "N" "-1.91" "N"
488561 "chr21:35821640:C>T" "KCNE1" "NM_001270405:p.Arg98Gln" "NM_001270405:c.293G>A" "EXON3" "Unknown significance" "rs150454912" "This variant is a VUS because it does not have enough information." 0.807 "N" "0.008;.;0.008;.;0.008;0.008;0.008;0.008" "D;.;D;.;D;D;D;D" "0.991" "D" 0.004623 "N" 0.621326 "N" "4.94" "C" 1 8600 0.000116279 0 4406 0 1 13006 0.0000768876 0 10324 0 0 11566 0 2 8624 0.000231911 0 6614 0 3 66406 0.0000451766 0 906 0 2 16508 0.000121153 7 120948 0.0000578761
488562 "chr21:35821641:G>A" "KCNE1" "NM_001270405:p.Arg98Trp" "NM_001270405:c.292C>T" "EXON3" "Pathogenic" "Long QT syndrome" "10973849|23994779|19907016|23861362|16922724" "rs199473362" "Pathogenicity is based on ClinVar submissions and the literature provided in PubMed." 0.902 "N" "0.001;.;0.001;.;0.001;0.001;0.001;0.001" "D;.;D;.;D;D;D;D" "1.0" "D" 0.004623 "N" 0.814144 "D" "3.96" "C" 0 10334 0 0 11566 0 1 8626 0.000115929 0 6614 0 1 66418 0.0000150562 0 906 0 0 16508 0 2 120972 0.0000165328
488563 "chr21:35821641:G>T" "KCNE1" "NM_001270405:p.Arg98Arg" "NM_001270405:c.292C>A" "EXON3" "Unknown significance" "rs199473362" "This variant is a VUS because it does not have enough information." 0 10334 0 0 11566 0 0 8626 0 0 6614 0 1 66418 0.0000150562 0 906 0 0 16508 0 1 120972 0.00000826638
488564 "chr21:35821644:C>A" "KCNE1" "NM_001270405:p.Ala97Ser" "NM_001270405:c.289G>T" "EXON3" "Likely benign" "rs762348330" "Pathogenicity is based on prediction data only. 1 out of 6 predictions were pathogenic." -0.013 "N" "0.115;.;0.115;.;0.115;0.115;0.115;0.115" "T;.;T;.;T;T;T;T" "0.0" "B" 0.070054 "N" 0.969431 "N" "3.1" "C"
488565 "chr21:35821646:T>C" "KCNE1" "NM_001270405:p.Gln96Arg" "NM_001270405:c.287A>G" "EXON3" "Unknown significance" "rs767972997" "This variant is a VUS because it does not have enough information." 0.913 "N" "0.014;.;0.014;.;0.014;0.014;0.014;0.014" "D;.;D;.;D;D;D;D" "0.907" "P" 0.002277 "N" 0.963904 "D" "3.8" "C" 1 10358 0.0000965437 0 11568 0 0 8628 0 0 6614 0 0 66476 0 0 906 0 0 16508 0 1 121058 0.0000082605
488566 "chr21:35821650:C>T" "KCNE1" "NM_001270405:p.Val95Ile" "NM_001270405:c.283G>A" "EXON3" "Likely benign" "rs772405174" "Pathogenicity is based on prediction data only. 0 out of 6 predictions were pathogenic." -0.063 "N" "0.405;.;0.405;.;0.405;0.405;0.405;0.405" "T;.;T;.;T;T;T;T" "0.003" "B" 0.30043 "N" 1 "N" "-2.95" "N" 0 10364 0 0 11566 0 0 8628 0 0 6614 0 1 66512 0.0000150349 0 908 0 0 16508 0 1 121100 0.00000825764
488567 "chr21:35821654:G>T" "KCNE1" "NM_001270405:p.Ala93Ala" "NM_001270405:c.279C>A" "EXON3" "Unknown significance" "rs775876249" "This variant is a VUS because it does not have enough information." 0 10364 0 0 11570 0 0 8628 0 0 6614 0 1 66522 0.0000150326 0 908 0 0 16510 0 1 121116 0.00000825655
488568 "chr21:35821656:C>T" "KCNE1" "NM_001270405:p.Ala93Thr" "NM_001270405:c.277G>A" "EXON3" "Pathogenic" "Long QT syndrome" "24606995" "Pathogenicity is based on the literature provided in PubMed." 0.807 "N" "0.057;.;0.057;.;0.057;0.057;0.057;0.057" "T;.;T;.;T;T;T;T" "0.737" "P" 0.097968 "N" 0.868928 "N" "4.06" "C"
488569 "chr21:35821657:C>T" "KCNE1" "NM_001270405:p.Lys92Lys" "NM_001270405:c.276G>A" "EXON3" "Unknown significance" "rs760884789" "This variant is a VUS because it does not have enough information." 0 10370 0 0 11570 0 0 8628 0 0 6614 0 1 66536 0.0000150295 0 908 0 0 16510 0 1 121136 0.00000825518
488570 "chr21:35821660:G>T" "KCNE1" "NM_001270405:p.Asp91Glu" "NM_001270405:c.273C>A" "EXON3" "Likely pathogenic" "Long QT syndrome" "24217263" "rs146614850" "Pathogenicity is based on the literature provided in PubMed." 0.902 "N" "0.18;.;0.18;.;0.18;0.18;0.18;0.18" "T;.;T;.;T;T;T;T" "0.015" "B" 0.00036 "D" 0.971247 "N" "4.94" "C" 0 8600 0 1 4406 0.000226963 1 13006 0.0000768876 1 10372 0.0000964134 0 11570 0 0 8632 0 0 6614 0 0 66542 0 0 908 0 0 16510 0 1 121148 0.00000825437
488571 "chr21:35821662:C>T" "KCNE1" "NM_001270405:p.Asp91Asn" "NM_001270405:c.271G>A" "EXON3" "Unknown significance" "rs753805986" "This variant is a VUS because it does not have enough information." 0.807 "N" "0.317;.;0.317;.;0.317;0.317;0.317;0.317" "T;.;T;.;T;T;T;T" "0.658" "P" 0.00036 "D" 0.829521 "D" "4.94" "C" 0 10374 0 0 11570 0 1 8632 0.000115848 0 6614 0 0 66544 0 0 908 0 0 16510 0 1 121152 0.00000825409
488572 "chr21:35821663:C>T" "KCNE1" "NM_001270405:p.Lys90Lys" "NM_001270405:c.270G>A" "EXON3" "Unknown significance" "rs761980578" "This variant is a VUS because it does not have enough information." 0 10376 0 0 11570 0 0 8632 0 0 6614 0 0 66544 0 0 908 0 1 16510 0.0000605694 1 121154 0.00000825396
488573 "chr21:35821666:C>T" "KCNE1" "NM_001270405:p.Glu89Glu" "NM_001270405:c.267G>A" "EXON3" "Unknown significance" "rs141290025" "This variant is a VUS because it does not have enough information." 1 8600 0.000116279 0 4406 0 1 13006 0.0000768876 0 10376 0 0 11570 0 0 8634 0 0 6614 0 1 66550 0.0000150263 0 908 0 0 16510 0 1 121162 0.00000825341
488574 "chr21:35821671:G>T" "KCNE1" "NM_001270405:p.Gln88Lys" "NM_001270405:c.262C>A" "EXON3" "Likely benign" "rs750349088" "Pathogenicity is based on prediction data only. 1 out of 6 predictions were pathogenic." 0.902 "N" "0.615;.;0.615;.;0.615;0.615;0.615;0.615" "T;.;T;.;T;T;T;T" "0.239" "B" 0.077895 "N" 0.832529 "N" "3.24" "C" 0 10380 0 0 11570 0 0 8634 0 0 6614 0 1 66558 0.0000150245 0 908 0 0 16510 0 1 121174 0.0000082526
488575 "chr21:35821674:A>G" "KCNE1" "NM_001270405:p.Trp87Arg" "NM_001270405:c.259T>C" "EXON3" "Pathogenic" "Long QT syndrome" "10400998|12566567" "rs199473361" "Pathogenicity is based on ClinVar submissions and the literature provided in PubMed." 1.028 "C" "0.006;.;0.006;.;0.006;0.006;0.006;0.006" "D;.;D;.;D;D;D;D" "1.0" "D" 0 "D" 0.999895 "D" "5.16" "C"
488576 "chr21:35821680:C>T" "KCNE1" "NM_001270405:p.Asp85Asn" "NM_001270405:c.253G>A" "EXON3" "Benign*" "rs1805128" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005. Additionally this variant has been reported pathogenic in ClinVar." 0.807 "N" "0.034;.;0.034;.;0.034;0.034;0.034;0.034" "D;.;D;.;D;D;D;D" "0.575" "P" 0.000004 "N" 0.999452 "N" "4.24" "C" 105 8600 0.0122093 9 4406 0.00204267 114 13006 0.00876519 2 1322 0.0015 9 1006 0.0089 2 694 0.0029 5 1008 0.005 1 978 0.001 19 5008 0.00379393 19 10382 0.00183009 22 11570 0.00190147 48 8636 0.00555813 109 6614 0.0164802 882 66588 0.0132456 7 908 0.00770925 23 16510 0.0013931 1110 121208 0.00915781
488577 "chr21:35821681:G>A" "KCNE1" "NM_001270405:p.Ser84Ser" "NM_001270405:c.252C>T" "EXON3" "Unknown significance" "rs138884514" "This variant is a VUS because it does not have enough information." 0 8600 0 1 4406 0.000226963 1 13006 0.0000768876 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 2 10384 0.000192604 0 11570 0 0 8636 0 1 6614 0.000151194 7 66590 0.000105121 0 908 0 1 16510 0.0000605694 11 121212 0.0000907501
488578 "chr21:35821681:G>T" "KCNE1" "NM_001270405:p.Ser84Ser" "NM_001270405:c.252C>A" "EXON3" "Unknown significance" "rs138884514" "This variant is a VUS because it does not have enough information." 0 10384 0 0 11570 0 0 8636 0 0 6614 0 1 66590 0.0000150173 0 908 0 0 16510 0 1 121212 0.00000825001
488579 "chr21:35821686:C>T" "KCNE1" "NM_001270405:p.Glu83Lys" "NM_001270405:c.247G>A" "EXON3" "Pathogenic" "Long QT syndrome" "19716085" "rs199473360" "Pathogenicity is based on ClinVar submissions and the literature provided in PubMed." 0.807 "N" "0.144;.;0.144;.;0.144;0.144;0.144;0.144" "T;.;T;.;T;T;T;T" "0.805" "P" 0.024672 "N" 0.934102 "N" "2.13" "C" 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681 0 10384 0 1 11570 0.0000864304 0 8638 0 0 6614 0 1 66594 0.0000150164 0 908 0 1 16510 0.0000605694 3 121218 0.0000247488
488580 "chr21:35821687:G>C" "KCNE1" "NM_001270405:p.Ile82Met" "NM_001270405:c.246C>G" "EXON3" "Unknown significance" "rs555086287" "This variant is a VUS because it does not have enough information." 0.038 "N" "0.0;.;0.0;.;0.0;0.0;0.0;0.0" "D;.;D;.;D;D;D;D" "1.0" "D" 0 "D" 0.938754 "D" "0.599" "C" 0 10386 0 0 11568 0 0 8638 0 0 6614 0 1 66602 0.0000150146 0 908 0 0 16510 0 1 121226 0.00000824906
488581 "chr21:35821687:G>A" "KCNE1" "NM_001270405:p.Ile82Ile" "NM_001270405:c.246C>T" "EXON3" "Unknown significance" "rs555086287" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 1 10386 0.0000962835 0 11568 0 0 8638 0 0 6614 0 0 66602 0 0 908 0 4 16510 0.000242277 5 121226 0.0000412453
488582 "chr21:35821691:T>C" "KCNE1" "NM_001270405:p.Tyr81Cys" "NM_001270405:c.242A>G" "EXON3" "Pathogenic" "Long QT syndrome" "16945797|16155735" "rs199473359" "Pathogenicity is based on ClinVar submissions and the literature provided in PubMed." 0.913 "N" "0.0;.;0.0;.;0.0;0.0;0.0;0.0" "D;.;D;.;D;D;D;D" "1.0" "D" 0.000001 "D" 0.999984 "D" "5.16" "C"
488583 "chr21:35821691:T>A" "KCNE1" "NM_001270405:p.Tyr81Phe" "NM_001270405:c.242A>T" "EXON3" "Benign" "10428953" "rs199473359" "Pathogenicity is based on ClinVar submissions. All submitters agree with this pathogenicity." 0.913 "N" "0.0;.;0.0;.;0.0;0.0;0.0;0.0" "D;.;D;.;D;D;D;D" "0.994" "D" 0.000001 "D" 0.99969 "D" "5.16" "C"
488584 "chr21:35821695:C>T" "KCNE1" "NM_001270405:p.Val80Ile" "NM_001270405:c.238G>A" "EXON3" "Likely pathogenic" "Long QT syndrome" "24667783" "rs769368494" "Pathogenicity is based on the literature provided in PubMed." 0.807 "N" "0.257;.;0.257;.;0.257;0.257;0.257;0.257" "T;.;T;.;T;T;T;T" "0.015" "B" 0.079382 "N" 0.999999 "N" "3.34" "C" 0 10390 0 0 11570 0 0 8640 0 0 6614 0 4 66620 0.000060042 0 908 0 0 16510 0 4 121252 0.0000329891
488585 "chr21:35821695:C>G" "KCNE1" "NM_001270405:p.Val80Leu" "NM_001270405:c.238G>C" "EXON3" "Likely benign" "rs769368494" "Pathogenicity is based on prediction data only. 1 out of 6 predictions were pathogenic." 0.807 "N" "0.424;.;0.424;.;0.424;0.424;0.424;0.424" "T;.;T;.;T;T;T;T" "0.095" "B" 0.079382 "N" 0.999995 "N" "3.34" "C" 0 10390 0 0 11570 0 1 8640 0.000115741 0 6614 0 0 66620 0 0 908 0 1 16510 0.0000605694 2 121252 0.0000164946
488586 "chr21:35821696:G>A" "KCNE1" "NM_001270405:p.Asn79Asn" "NM_001270405:c.237C>T" "EXON3" "Unknown significance" "rs746345034" "This variant is a VUS because it does not have enough information." 0 10390 0 1 11570 0.0000864304 1 8640 0.000115741 0 6614 0 1 66624 0.0000150096 0 904 0 1 16510 0.0000605694 4 121252 0.0000329891
488587 "chr21:35821698:T>C" "KCNE1" "NM_001270405:p.Asn79Asp" "NM_001270405:c.235A>G" "EXON3" "Benign" "10428953" "rs199473358" "Pathogenicity is based on ClinVar submissions. All submitters agree with this pathogenicity." 0.913 "N" "0.038;.;0.038;.;0.038;0.038;0.038;0.038" "D;.;D;.;D;D;D;D" "0.985" "D" 0.000003 "D" 0.994416 "D" "3.97" "C"
488588 "chr21:35821702:T>C" "KCNE1" "NM_001270405:p.Pro77Pro" "NM_001270405:c.231A>G" "EXON3" "Unknown significance" "rs775823236" "This variant is a VUS because it does not have enough information." 0 10390 0 0 11570 0 0 8640 0 0 6614 0 0 66622 0 0 906 0 1 16510 0.0000605694 1 121252 0.00000824729
488589 "chr21:35821704:GGT>TAGA" "KCNE1" "Pathogenic" "Long QT syndrome" "19716085" "Pathogenicity is based on the literature provided in PubMed."
488590 "chr21:35821707:C>T" "KCNE1" "NM_001270405:p.Asp76Asn" "NM_001270405:c.226G>A" "EXON3" "Pathogenic" "Jervell and Lange-Nielsen syndrome" "20301579|20301308|9445165|9354783|9328483|11874988|3|16818210|9|15840476|12566567|9354802|19716085|25637381" "rs74315445" "Pathogenicity is based on ClinVar submissions and the literature provided in PubMed." 0.807 "N" "0.086;.;0.086;.;0.086;0.086;0.086;0.086" "T;.;T;.;T;T;T;T" "0.983" "D" 0.000005 "D" 0.973685 "A" "5.16" "C" 1 8600 0.000116279 0 4406 0 1 13006 0.0000768876 0 10390 0 0 11570 0 0 8640 0 0 6612 0 4 66618 0.0000600438 0 906 0 0 16510 0 4 121246 0.0000329908
488591 "chr21:35821708:G>A" "KCNE1" "NM_001270405:p.Asn75Asn" "NM_001270405:c.225C>T" "EXON3" "Unknown significance" "rs79175878" "This variant is a VUS because it does not have enough information." 0 8600 0 1 4406 0.000226963 1 13006 0.0000768876 3 10388 0.000288795 0 11570 0 1 8640 0.000115741 0 6612 0 3 66624 0.0000450288 0 906 0 1 16512 0.000060562 8 121252 0.0000659783
488592 "chr21:35821711:C>T" "KCNE1" "NM_001270405:p.Ser74Ser" "NM_001270405:c.222G>A" "EXON3" "Unknown significance" "rs766767618" "This variant is a VUS because it does not have enough information." 0 10390 0 0 11570 0 0 8640 0 0 6612 0 2 66632 0.0000300156 0 904 0 0 16512 0 2 121260 0.0000164935
488593 "chr21:35821712:G>A" "KCNE1" "NM_001270405:p.Ser74Leu" "NM_001270405:c.221C>T" "EXON3" "Pathogenic" "Long QT syndrome" "20301308|9354802|15051636|19907016" "rs74315446" "Pathogenicity is based on ClinVar submissions and the literature provided in PubMed." 0.902 "N" "0.003;.;0.003;.;0.003;0.003;0.003;0.003" "D;.;D;.;D;D;D;D" "1.0" "D" 0 "D" 0.999926 "A" "5.16" "C" 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681 0 10390 0 0 11570 0 0 8638 0 0 6612 0 2 66630 0.0000300165 0 906 0 0 16512 0 2 121258 0.0000164938
488594 "chr21:35821713:A>C" "KCNE1" "NM_001270405:p.Ser74Ala" "NM_001270405:c.220T>G" "EXON3" "Benign" "10428953" "rs199473357" "Pathogenicity is based on ClinVar submissions. All submitters agree with this pathogenicity." 1.028 "C" "0.024;.;0.024;.;0.024;0.024;0.024;0.024" "D;.;D;.;D;D;D;D" "0.905" "P" 0 "D" 0.994899 "D" "5.16" "C"
488595 "chr21:35821713:A>G" "KCNE1" "NM_001270405:p.Ser74Pro" "NM_001270405:c.220T>C" "EXON3" "Unknown significance" "rs199473357" "This variant is a VUS because it does not have enough information." 1.028 "C" "0.068;.;0.068;.;0.068;0.068;0.068;0.068" "T;.;T;.;T;T;T;T" "0.664" "P" 0 "D" 0.999773 "D" "5.16" "C" 0 10390 0 2 11568 0.000172891 0 8640 0 0 6612 0 0 66634 0 0 906 0 0 16512 0 2 121262 0.0000164932
488596 "chr21:35821723:C>G" "KCNE1" "NM_001270405:p.Lys70Asn" "NM_001270405:c.210G>C" "EXON3" "Pathogenic" "Long QT syndrome" "16155735" "rs199473356" "Pathogenicity is based on ClinVar submissions and the literature provided in PubMed." -0.537 "N" "0.003;.;0.003;.;0.003;0.003;0.003;0.003" "D;.;D;.;D;D;D;D" "0.998" "D" 0.000046 "D" 0.97771 "D" "-3.61" "N"
488597 "chr21:35821724:T>A" "KCNE1" "NM_001270405:p.Lys70Met" "NM_001270405:c.209A>T" "EXON3" "Pathogenic" "Long QT syndrome" "19716085" "rs199473646" "Pathogenicity is based on ClinVar submissions and the literature provided in PubMed." 0.913 "N" "0.001;.;0.001;.;0.001;0.001;0.001;0.001" "D;.;D;.;D;D;D;D" "0.999" "D" 0.000046 "D" 0.996319 "D" "5.16" "C" 0 10390 0 0 11570 0 0 8642 0 0 6612 0 1 66644 0.0000150051 0 906 0 0 16512 0 1 121276 0.00000824565
488598 "chr21:35821726:C>T" "KCNE1" "NM_001270405:p.Lys69Lys" "NM_001270405:c.207G>A" "EXON3" "Unknown significance" "rs762968991" "This variant is a VUS because it does not have enough information." 0 10390 0 0 11570 0 0 8642 0 0 6612 0 3 66650 0.0000450113 0 906 0 0 16512 0 3 121282 0.0000247357
488599 "chr21:35821727:T>C" "KCNE1" "NM_001270405:p.Lys69Arg" "NM_001270405:c.206A>G" "EXON3" "Likely benign" "14661677|23861362" "rs149338401" "Pathogenicity is based on ClinVar submissions. All submitters agree with this pathogenicity." 0.913 "N" "0.338;.;0.338;.;0.338;0.338;0.338;0.338" "T;.;T;.;T;T;T;T" "0.137" "B" 0.000519 "N" 0.686838 "D" "4.0" "C" 0 8600 0 1 4406 0.000226963 1 13006 0.0000768876 5 10390 0.000481232 0 11570 0 0 8642 0 0 6612 0 0 66650 0 0 906 0 0 16512 0 5 121282 0.0000412262
488600 "chr21:35821729:G>A" "KCNE1" "NM_001270405:p.Ser68Ser" "NM_001270405:c.204C>T" "EXON3" "Unknown significance" "rs751332000" "This variant is a VUS because it does not have enough information."
488601 "chr21:35821731:A>T" "KCNE1" "NM_001270405:p.Ser68Thr" "NM_001270405:c.202T>A" "EXON3" "Unknown significance" "10428953" "rs199473393" "Pathogenicity is based on ClinVar submissions. All submitters agree with this pathogenicity." 1.028 "C" "0.003;.;0.003;.;0.003;0.003;0.003;0.003" "D;.;D;.;D;D;D;D" "0.938" "P" 0.000011 "D" 0.971372 "D" "5.16" "C"
488602 "chr21:35821733:C>T" "KCNE1" "NM_001270405:p.Arg67His" "NM_001270405:c.200G>A" "EXON3" "Pathogenic" "Long QT syndrome" "23994779|19716085|25637381" "rs79654911" "Pathogenicity is based on ClinVar submissions and the literature provided in PubMed." 0.807 "N" "0.002;.;0.002;.;0.002;0.002;0.002;0.002" "D;.;D;.;D;D;D;D" "1.0" "D" 0.000053 "D" 0.999993 "D" "5.16" "C" 0 8600 0 3 4406 0.00068089 3 13006 0.000230663 2 10390 0.000192493 0 11572 0 0 8642 0 0 6612 0 3 66654 0.0000450086 0 906 0 0 16512 0 5 121288 0.0000412242
488603 "chr21:35821734:G>A" "KCNE1" "NM_001270405:p.Arg67Cys" "NM_001270405:c.199C>T" "EXON3" "Pathogenic" "Long QT syndrome" "19716085|24033266" "rs199473645" "Pathogenicity is based on ClinVar submissions and the literature provided in PubMed." 0.902 "N" "0.0;.;0.0;.;0.0;0.0;0.0;0.0" "D;.;D;.;D;D;D;D" "1.0" "D" 0.000053 "D" 1 "D" "5.16" "C" 1 10390 0.0000962464 1 11572 0.0000864155 0 8642 0 0 6612 0 1 66654 0.0000150029 0 906 0 0 16512 0 3 121288 0.0000247345
488604 "chr21:35821734:G>T" "KCNE1" "NM_001270405:p.Arg67Ser" "NM_001270405:c.199C>A" "EXON3" "Unknown significance" "rs199473645" "This variant is a VUS because it does not have enough information." 0.902 "N" "0.002;.;0.002;.;0.002;0.002;0.002;0.002" "D;.;D;.;D;D;D;D" "1.0" "D" 0.000053 "D" 0.999994 "D" "5.16" "C" 0 10390 0 0 11572 0 0 8642 0 0 6612 0 1 66654 0.0000150029 0 906 0 0 16512 0 1 121288 0.00000824484
488605 "chr21:35821752:T>C" "KCNE1" "NM_001270405:p.Ile61Val" "NM_001270405:c.181A>G" "EXON3" "Unknown significance" "rs143661740" "This variant is a VUS because it does not have enough information." 0.913 "N" "0.228;.;0.228;.;0.228;0.228;0.228;0.228" "T;.;T;.;T;T;T;T" "0.104" "B" 0.000077 "D" 0.936135 "D" "5.16" "C" 1 8600 0.000116279 0 4406 0 1 13006 0.0000768876 0 10394 0 0 11572 0 0 8642 0 0 6610 0 1 66670 0.0000149993 0 906 0 0 16512 0 1 121306 0.00000824362
488606 "chr21:35821754:C>T" "KCNE1" "NM_001270405:p.Gly60Asp" "NM_001270405:c.179G>A" "EXON3" "Pathogenic" "Atrial fibrillation, early-onset" "22471742" "rs758961135" "Pathogenicity is based on the literature provided in PubMed." 0.807 "N" "0.001;.;0.001;.;0.001;0.001;0.001;0.001" "D;.;D;.;D;D;D;D" "1.0" "D" 0.000013 "D" 0.999999 "D" "5.16" "C" 0 10394 0 0 11572 0 0 8644 0 0 6612 0 1 66666 0.0000150002 0 906 0 0 16512 0 1 121306 0.00000824362
488607 "chr21:35821756:CAGGGT>AGGGGG" "KCNE1" "Pathogenic" "Jervell and Lange-Nielsen syndrome" "20301579|9328483|11530100" "rs281865421" "Pathogenicity is based on ClinVar submissions and the literature provided in PubMed."
488608 "chr21:35821756:C>A" "KCNE1" "NM_001270405:p.Leu59Leu" "NM_001270405:c.177G>T" "EXON3" "Unknown significance" "rs748857341" "This variant is a VUS because it does not have enough information." 0 10390 0 0 11570 0 0 8644 0 0 6612 0 2 66670 0.0000299985 0 906 0 0 16512 0 2 121304 0.0000164875
488609 "chr21:35821756:C>G" "KCNE1" "NM_001270405:p.Leu59Leu" "NM_001270405:c.177G>C" "EXON3" "Unknown significance" "rs748857341" "This variant is a VUS because it does not have enough information." 0 10390 0 0 11570 0 2 8644 0.000231374 0 6612 0 0 66670 0 0 906 0 0 16512 0 2 121304 0.0000164875
488610 "chr21:35821757:A>G" "KCNE1" "NM_001270405:p.Leu59Pro" "NM_001270405:c.176T>C" "EXON3" "Pathogenic" "Long QT syndrome" "19716085" "rs141813529" "Pathogenicity is based on ClinVar submissions and the literature provided in PubMed." 1.028 "C" "0.015;.;0.015;.;0.015;0.015;0.015;0.015" "D;.;D;.;D;D;D;D" "0.998" "D" 0.014427 "N" 1 "A" "5.16" "C" 0 10394 0 0 11572 0 0 8642 0 0 6612 0 2 66670 0.0000299985 0 906 0 0 16512 0 2 121308 0.000016487
488611 "chr21:35821758:G>C" "KCNE1" "NM_001270405:p.Leu59Val" "NM_001270405:c.175C>G" "EXON3" "Likely benign" "rs754731040" "Pathogenicity is based on prediction data only. 2 out of 6 predictions were pathogenic." 0.902 "N" "0.381;.;0.381;.;0.381;0.381;0.381;0.381" "T;.;T;.;T;T;T;T" "0.027" "B" 0.014427 "N" 0.523219 "D" "4.07" "C"
488612 "chr21:35821759:G>C" "KCNE1" "NM_001270405:p.Thr58Thr" "NM_001270405:c.174C>G" "EXON3" "Likely benign" "24033266" "rs727503101" "Pathogenicity is based on ClinVar submissions. All submitters agree with this pathogenicity."
488613 "chr21:35821760:G>A" "KCNE1" "NM_001270405:p.Thr58Ile" "NM_001270405:c.173C>T" "EXON3" "Unknown significance" "rs747321794" "This variant is a VUS because it does not have enough information." 0.902 "N" "0.199;.;0.199;.;0.199;0.199;0.199;0.199" "T;.;T;.;T;T;T;T" "1.0" "D" 0.000056 "D" 0.999991 "D" "5.16" "C" 0 10396 0 2 11570 0.000172861 0 8644 0 0 6612 0 0 66672 0 0 906 0 0 16512 0 2 121312 0.0000164864
488614 "chr21:35821761:T>G" "KCNE1" "NM_001270405:p.Thr58Pro" "NM_001270405:c.172A>C" "EXON3" "Pathogenic" "Long QT syndrome" "9328483|19716085" "rs147187721" "Pathogenicity is based on ClinVar submissions and the literature provided in PubMed." 0.913 "N" "0.006;.;0.006;.;0.006;0.006;0.006;0.006" "D;.;D;.;D;D;D;D" "0.999" "D" 0.000056 "D" 0.999989 "A" "5.16" "C" 0 10394 0 0 11572 0 0 8642 0 0 6610 0 2 66670 0.0000299985 0 906 0 0 16512 0 2 121306 0.0000164872
488615 "chr21:35821762:G>A" "KCNE1" "NM_001270405:p.Phe57Phe" "NM_001270405:c.171C>T" "EXON3" "Unknown significance" "rs543789658" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681 0 10396 0 0 11572 0 0 8642 0 0 6610 0 0 66670 0 0 906 0 1 16512 0.000060562 1 121308 0.00000824348
488616 "chr21:35821770:C>T" "KCNE1" "NM_001270405:p.Gly55Ser" "NM_001270405:c.163G>A" "EXON3" "Pathogenic" "Long QT syndrome" "19716085|24033266" "rs199473644" "Pathogenicity is based on ClinVar submissions and the literature provided in PubMed." 0.807 "N" "0.283;.;0.283;.;0.283;0.283;0.283;0.283" "T;.;T;.;T;T;T;T" "0.979" "D" 0.000204 "D" 0.999986 "D" "5.16" "C" 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 1 978 0.001 2 5008 0.000399361 0 10398 0 0 11574 0 1 8646 0.00011566 0 6610 0 4 66674 0.0000599934 0 906 0 11 16512 0.000666182 16 121320 0.000131883
488617 "chr21:35821771:G>A" "KCNE1" "NM_001270405:p.Phe54Phe" "NM_001270405:c.162C>T" "EXON3" "Benign" "rs17173508" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1 8600 0.000116279 0 4406 0 1 13006 0.0000768876 1 1322 0.0008 0 1006 0 0 694 0 13 1008 0.0129 1 978 0.001 15 5008 0.00299521 7 10398 0.000673206 0 11574 0 42 8646 0.00485774 0 6610 0 1 66676 0.0000149979 0 906 0 4 16512 0.000242248 54 121322 0.000445097
488618 "chr21:35821773:A>C" "KCNE1" "NM_001270405:p.Phe54Val" "NM_001270405:c.160T>G" "EXON3" "Likely pathogenic" "Sudden unexplained nocturnal death syndrome" "23890619" "Pathogenicity is based on the literature provided in PubMed." 1.028 "C" "0.002;.;0.002;.;0.002;0.002;0.002;0.002" "D;.;D;.;D;D;D;D" "0.987" "D" 0 "D" 0.999988 "D" "5.16" "C"
488619 "chr21:35821775:A>G" "KCNE1" "NM_001270405:p.Phe53Ser" "NM_001270405:c.158T>C" "EXON3" "Pathogenic" "Long QT syndrome" "16414944" "rs199473355" "Pathogenicity is based on ClinVar submissions and the literature provided in PubMed." 1.028 "C" "0.002;.;0.002;.;0.002;0.002;0.002;0.002" "D;.;D;.;D;D;D;D" "0.998" "D" 0.000387 "D" 0.998962 "D" "5.34" "C"
488620 "chr21:35821778:C>G" "KCNE1" "NM_001270405:p.Gly52Ala" "NM_001270405:c.155G>C" "EXON3" "Benign" "14661677" "rs17173509" "Pathogenicity is based on ClinVar submissions. All submitters agree with this pathogenicity." 0.807 "N" "0.206;.;0.206;.;0.206;0.206;0.206;0.206" "T;.;T;.;T;T;T;T" "0.988" "D" 0 "D" 0.999959 "D" "5.34" "C"
488621 "chr21:35821779:C>T" "KCNE1" "NM_001270405:p.Gly52Arg" "NM_001270405:c.154G>A" "EXON3" "Pathogenic" "Long QT syndrome" "14499862|19907016" "rs199473354" "Pathogenicity is based on ClinVar submissions and the literature provided in PubMed." 0.807 "N" "0.011;.;0.011;.;0.011;0.011;0.011;0.011" "D;.;D;.;D;D;D;D" "0.998" "D" 0 "D" 0.999919 "D" "4.44" "C"
488622 "chr21:35821780:CA>AT" "KCNE1" "Pathogenic" "Long QT syndrome" "10400998" "Pathogenicity is based on the literature provided in PubMed."
488623 "chr21:35821786:C>T" "KCNE1" "NM_001270405:p.Met49Ile" "NM_001270405:c.147G>A" "EXON3" "Pathogenic" "Long QT syndrome" "23631430" "rs773365460" "Pathogenicity is based on the literature provided in PubMed." 0.807 "N" "0.22;.;0.22;.;0.22;0.22;0.22;0.22" "T;.;T;.;T;T;T;T" "0.0" "B" 0.000521 "N" 0.958736 "D" "1.15" "C" 0 10396 0 0 11574 0 0 8646 0 0 6608 0 1 66678 0.0000149975 0 906 0 0 16512 0 1 121320 0.00000824266
488624 "chr21:35821791:G>A" "KCNE1" "NM_001270405:p.Leu48Phe" "NM_001270405:c.142C>T" "EXON3" "Unknown significance" "rs75610894" "This variant is a VUS because it does not have enough information." 0.902 "N" "0.004;.;0.004;.;0.004;0.004;0.004;0.004" "D;.;D;.;D;D;D;D" "0.999" "D" 0.000746 "D" 0.999994 "D" "5.34" "C" 2 8600 0.000232558 0 4406 0 2 13006 0.000153775 0 10396 0 0 11574 0 0 8644 0 0 6604 0 5 66678 0.0000749873 0 904 0 0 16512 0 5 121312 0.000041216
488625 "chr21:35821794:C>A" "KCNE1" "NM_001270405:p.Val47Phe" "NM_001270405:c.139G>T" "EXON3" "Pathogenic" "Long QT syndrome" "10400998" "rs199473353" "Pathogenicity is based on ClinVar submissions and the literature provided in PubMed." -0.005 "N" "0.004;.;0.004;.;0.004;0.004;0.004;0.004" "D;.;D;.;D;D;D;D" "0.769" "P" 0.018657 "N" 0.920386 "D" "1.67" "C"
488626 "chr21:35821794:C>T" "KCNE1" "NM_001270405:p.Val47Ile" "NM_001270405:c.139G>A" "EXON3" "Benign" "rs199473353" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." -0.005 "N" "1.0;.;1.0;.;1.0;1.0;1.0;1.0" "T;.;T;.;T;T;T;T" "0.0" "B" 0.018657 "N" 0.773751 "N" "1.67" "C" 0 1322 0 0 1006 0 4 694 0.0058 1 1008 0.001 0 978 0 5 5008 0.000998403 0 10398 0 7 11574 0.000604804 1 8646 0.00011566 0 6606 0 5 66678 0.0000749873 2 906 0.00220751 2 16512 0.000121124 17 121320 0.000140125
488627 "chr21:35821795:G>T" "KCNE1" "NM_001270405:p.Tyr46Stop" "NM_001270405:c.138C>A" "EXON3" "Unknown significance" "rs758346045" "This variant is a VUS because it does not have enough information." -0.389 "N" 0.000001 "D" 1 "D" "1.42" "C" 0 10398 0 0 11574 0 0 8648 0 0 6608 0 1 66680 0.000014997 0 906 0 0 16512 0 1 121326 0.00000824226
488628 "chr21:35821795:G>A" "KCNE1" "NM_001270405:p.Tyr46Tyr" "NM_001270405:c.138C>T" "EXON3" "Unknown significance" "rs758346045" "This variant is a VUS because it does not have enough information." 0 10398 0 0 11574 0 1 8648 0.000115634 0 6608 0 0 66680 0 0 906 0 0 16512 0 1 121326 0.00000824226
488629 "chr21:35821803:C>T" "KCNE1" "NM_001270405:p.Ala44Thr" "NM_001270405:c.130G>A" "EXON3" "Likely benign" "rs767315445" "Pathogenicity is based on prediction data only. 2 out of 6 predictions were pathogenic." 0.807 "N" "0.17;.;0.17;.;0.17;0.17;0.17;0.17" "T;.;T;.;T;T;T;T" "0.744" "P" 0.012146 "N" 0.854964 "N" "5.34" "C" 0 10398 0 0 11572 0 0 8648 0 0 6604 0 1 66672 0.0000149988 0 906 0 0 16512 0 1 121312 0.00000824321
488630 "chr21:35821804:C>T" "KCNE1" "NM_001270405:p.Glu43Glu" "NM_001270405:c.129G>A" "EXON3" "Unknown significance" "rs560251161" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681 0 10398 0 0 11574 0 0 8648 0 0 6604 0 0 66676 0 0 906 0 2 16512 0.000121124 2 121318 0.0000164856
488631 "chr21:35821806:C>T" "KCNE1" "NM_001270405:p.Glu43Lys" "NM_001270405:c.127G>A" "EXON3" "Unknown significance" "rs755781709" "This variant is a VUS because it does not have enough information." 0.807 "N" "0.028;.;0.028;.;0.028;0.028;0.028;0.028" "D;.;D;.;D;D;D;D" "0.866" "P" 0.009251 "N" 0.998318 "D" "5.34" "C" 0 10398 0 5 11574 0.000432003 0 8648 0 0 6606 0 0 66678 0 0 906 0 0 16512 0 5 121322 0.0000412126
488632 "chr21:35821810:C>G" "KCNE1" "NM_001270405:p.Lys41Asn" "NM_001270405:c.123G>C" "EXON3" "Likely benign" "rs763754260" "Pathogenicity is based on prediction data only. 1 out of 6 predictions were pathogenic." -0.013 "N" "0.389;.;0.389;.;0.389;0.389;0.389;0.389" "T;.;T;.;T;T;T;T" "0.197" "B" 0.564865 "N" 1 "N" "2.19" "C" 0 10394 0 0 11574 0 0 8646 0 0 6604 0 0 66676 0 0 906 0 1 16512 0.000060562 1 121312 0.00000824321
488633 "chr21:35821810:C>T" "KCNE1" "NM_001270405:p.Lys41Lys" "NM_001270405:c.123G>A" "EXON3" "Unknown significance" "rs763754260" "This variant is a VUS because it does not have enough information." 0 10394 0 0 11574 0 0 8646 0 0 6604 0 1 66676 0.0000149979 0 906 0 0 16512 0 1 121312 0.00000824321
488634 "chr21:35821813:G>A" "KCNE1" "NM_001270405:p.Gly40Gly" "NM_001270405:c.120C>T" "EXON3" "Unknown significance" "rs756778741" "This variant is a VUS because it does not have enough information." 1 10392 0.0000962279 0 11574 0 0 8644 0 0 6604 0 0 66668 0 0 906 0 0 16512 0 1 121300 0.00000824402
488635 "chr21:35821815:C>T" "KCNE1" "NM_001270405:p.Gly40Ser" "NM_001270405:c.118G>A" "EXON3" "Likely benign" "rs778439872" "Pathogenicity is based on prediction data only. 0 out of 6 predictions were pathogenic." 0.086 "N" "0.473;.;0.473;.;0.473;0.473;0.473;0.473" "T;.;T;.;T;T;T;T" "0.001" "B" 0.592725 "N" 1 "N" "-6.46" "N" 0 10392 0 21 11574 0.00181441 1 8646 0.00011566 0 6606 0 4 66668 0.0000599988 1 904 0.00110619 1 16512 0.000060562 28 121302 0.000230829
488636 "chr21:35821816:G>A" "KCNE1" "NM_001270405:p.Asp39Asp" "NM_001270405:c.117C>T" "EXON3" "Unknown significance" "rs368465967" "This variant is a VUS because it does not have enough information." 1 8600 0.000116279 0 4406 0 1 13006 0.0000768876 0 10392 0 0 11574 0 0 8646 0 0 6604 0 1 66668 0.0000149997 0 906 0 2 16512 0.000121124 3 121302 0.0000247317
488637 "chr21:35821818:C>T" "KCNE1" "NM_001270405:p.Asp39Asn" "NM_001270405:c.115G>A" "EXON3" "Benign" "10428953" "rs199473352" "Pathogenicity is based on ClinVar submissions. All submitters agree with this pathogenicity." 0.042 "N" "0.148;.;0.148;.;0.148;0.148;0.148;0.148" "T;.;T;.;T;T;T;T" "0.0" "B" 0.019517 "N" 1 "N" "3.21" "C"
488638 "chr21:35821821:T>C" "KCNE1" "NM_001270405:p.Ser38Gly" "NM_001270405:c.112A>G" "EXON3" "Benign" "rs1805127" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." -0.954 "N" "0.401;.;0.401;.;0.401;0.401;0.401;0.401" "T;.;T;.;T;T;T;T" "0.0" "B" 0.773538 "N" 1 "P" "0.18" "C" 5477 8600 0.63686 3132 4406 0.710849 8609 13006 0.661925 958 1322 0.7247 628 1006 0.6243 426 694 0.6138 714 1008 0.7083 649 978 0.6636 3375 5008 0.673922 7380 10384 0.710709 6875 11562 0.59462 6223 8622 0.721758 3706 6590 0.562367 42941 66652 0.644257 581 904 0.642699 10812 16510 0.654876 78518 121224 0.64771
488639 "chr21:35821822:G>A" "KCNE1" "NM_001270405:p.Ser37Ser" "NM_001270405:c.111C>T" "EXON3" "Unknown significance" "rs150458884" "This variant is a VUS because it does not have enough information." 0 8600 0 1 4406 0.000226963 1 13006 0.0000768876 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 1 10378 0.0000963577 0 11570 0 16 8628 0.00185443 0 6590 0 1 66534 0.0000150299 0 908 0 1 16510 0.0000605694 19 121118 0.000156872
488640 "chr21:35821824:T>C" "KCNE1" "NM_001270405:p.Ser37Gly" "NM_001270405:c.109A>G" "EXON3" "Unknown significance" "23861362" "rs202036483" "Pathogenicity is based on ClinVar submissions. All submitters agree with this pathogenicity." -2.435 "N" "0.401;.;0.401;.;0.401;0.401;0.401;0.401" "T;.;T;.;T;T;T;T" "0.0" "B" 0.019109 "N" 1 "N" "-9.88" "N"
488641 "chr21:35821825:G>A" "KCNE1" "NM_001270405:p.Arg36Arg" "NM_001270405:c.108C>T" "EXON3" "Unknown significance" "rs200187147" "This variant is a VUS because it does not have enough information." 0 10372 0 0 11572 0 0 8630 0 0 6590 0 1 66528 0.0000150313 0 908 0 0 16510 0 1 121110 0.00000825696
488642 "chr21:35821825:G>C" "KCNE1" "NM_001270405:p.Arg36Arg" "NM_001270405:c.108C>G" "EXON3" "Unknown significance" "rs200187147" "This variant is a VUS because it does not have enough information."
488643 "chr21:35821826:C>T" "KCNE1" "NM_001270405:p.Arg36His" "NM_001270405:c.107G>A" "EXON3" "Pathogenic" "Long QT syndrome" "16414944" "rs199473351" "Pathogenicity is based on ClinVar submissions and the literature provided in PubMed." -1.11 "N" "0.124;.;0.124;.;0.124;0.124;0.124;0.124" "T;.;T;.;T;T;T;T" "0.0" "B" 0.615695 "N" 1 "N" "1.02" "C" 0 1322 0 1 1006 0.001 0 694 0 1 1008 0.001 0 978 0 2 5008 0.000399361 3 10374 0.000289184 0 11572 0 1 8628 0.000115902 0 6588 0 5 66514 0.0000751721 0 908 0 2 16510 0.000121139 11 121094 0.0000908385
488644 "chr21:35821827:G>A" "KCNE1" "NM_001270405:p.Arg36Cys" "NM_001270405:c.106C>T" "EXON3" "Likely benign" "rs372398235" "Pathogenicity is based on prediction data only. 1 out of 6 predictions were pathogenic." -1.069 "N" "0.054;.;0.054;.;0.054;0.054;0.054;0.054" "T;.;T;.;T;T;T;T" "0.849" "P" 0.615695 "N" 1 "N" "-5.07" "N" 1 8600 0.000116279 0 4406 0 1 13006 0.0000768876
488645 "chr21:35821827:G>C" "KCNE1" "NM_001270405:p.Arg36Gly" "NM_001270405:c.106C>G" "EXON3" "Likely benign" "rs372398235" "Pathogenicity is based on prediction data only. 0 out of 6 predictions were pathogenic." -1.069 "N" "0.403;.;0.403;.;0.403;0.403;0.403;0.403" "T;.;T;.;T;T;T;T" "0.0" "B" 0.615695 "N" 1 "N" "-5.07" "N"
488646 "chr21:35821830:G>A" "KCNE1" "NM_001270405:p.Pro35Ser" "NM_001270405:c.103C>T" "EXON3" "Likely benign" "rs771113232" "Pathogenicity is based on prediction data only. 1 out of 6 predictions were pathogenic." 0.108 "N" "0.135;.;0.135;.;0.135;0.135;0.135;0.135" "T;.;T;.;T;T;T;T" "0.001" "B" 0.914573 "N" 1 "N" "0.812" "C" 0 10364 0 1 11570 0.0000864304 0 8628 0 0 6584 0 0 66500 0 0 908 0 0 16510 0 1 121064 0.00000826009
488647 "chr21:35821832:G>A" "KCNE1" "NM_001270405:p.Ser34Phe" "NM_001270405:c.101C>T" "EXON3" "Unknown significance" "rs774614463" "This variant is a VUS because it does not have enough information." 0.998 "C" "0.05;.;0.05;.;0.05;0.05;0.05;0.05" "D;.;D;.;D;D;D;D" "0.003" "B" 0.095631 "N" 1 "N" "1.8" "C" 0 10364 0 0 11570 0 0 8628 0 0 6582 0 0 66500 0 0 908 0 1 16510 0.0000605694 1 121062 0.00000826023
488648 "chr21:35821833:A>G" "KCNE1" "NM_001270405:p.Ser34Pro" "NM_001270405:c.100T>C" "EXON3" "Likely benign" "rs376479233" "Pathogenicity is based on prediction data only. 1 out of 6 predictions were pathogenic." 0.155 "N" "0.02;.;0.02;.;0.02;0.02;0.02;0.02" "D;.;D;.;D;D;D;D" "0.001" "B" 0.095631 "N" 1 "N" "-3.06" "N" 1 8600 0.000116279 0 4406 0 1 13006 0.0000768876 0 10360 0 0 11570 0 0 8624 0 0 6570 0 3 66468 0.0000451345 0 906 0 0 16510 0 3 121008 0.0000247917
488649 "chr21:35821834:C>A" "KCNE1" "NM_001270405:p.Arg33Ser" "NM_001270405:c.99G>T" "EXON3" "Likely benign" "rs771964597" "Pathogenicity is based on prediction data only. 1 out of 6 predictions were pathogenic." 0.042 "N" "0.369;.;0.369;.;0.369;0.369;0.369;0.369" "T;.;T;.;T;T;T;T" "0.046" "B" 0.110181 "N" 1 "N" "1.81" "C" 0 10364 0 0 11570 0 0 8626 0 0 6580 0 1 66470 0.0000150444 0 904 0 0 16510 0 1 121024 0.00000826282
488650 "chr21:35821838:C>T" "KCNE1" "NM_001270405:p.Arg32His" "NM_001270405:c.95G>A" "EXON3" "Likely pathogenic" "Long QT syndrome" "18752142|19716085|15051636|10973849" "rs17857111" "Pathogenicity is based on ClinVar submissions and the literature provided in PubMed." 0.012 "N" "0.073;.;0.073;.;0.073;0.073;0.073;0.073" "T;.;T;.;T;T;T;T" "0.01" "B" 0.034556 "N" 0.941872 "N" "2.91" "C" 0 10364 0 0 11568 0 0 8626 0 0 6582 0 4 66452 0.0000601938 0 906 0 2 16510 0.000121139 6 121008 0.0000495835
488651 "chr21:35821839:G>A" "KCNE1" "NM_001270405:p.Arg32Cys" "NM_001270405:c.94C>T" "EXON3" "Pathogenic" "Long QT syndrome" "23382499" "rs200963514" "Pathogenicity is based on the literature provided in PubMed." 0.998 "C" "0.015;.;0.015;.;0.015;0.015;0.015;0.015" "D;.;D;.;D;D;D;D" "0.023" "B" 0.034556 "N" 0.983138 "D" "3.91" "C" 0 10364 0 1 11568 0.0000864454 0 8626 0 0 6580 0 1 66444 0.0000150503 0 906 0 0 16510 0 2 120998 0.0000165292
488652 "chr21:35821841:G>A" "KCNE1" "NM_001270405:p.Ala31Val" "NM_001270405:c.92C>T" "EXON3" "Unknown significance" "rs532752739" "This variant is a VUS because it does not have enough information." 0.998 "C" "0.013;.;0.013;.;0.013;0.013;0.013;0.013" "D;.;D;.;D;D;D;D" "0.018" "B" 0.015463 "N" 0.784761 "D" "3.01" "C" 0 10364 0 0 11568 0 0 8624 0 0 6578 0 0 66432 0 0 906 0 1 16510 0.0000605694 1 120982 0.00000826569
488653 "chr21:35821842:C>T" "KCNE1" "NM_001270405:p.Ala31Thr" "NM_001270405:c.91G>A" "EXON3" "Unknown significance" "rs753462079" "This variant is a VUS because it does not have enough information." 0.892 "N" "0.174;.;0.174;.;0.174;0.174;0.174;0.174" "T;.;T;.;T;T;T;T" "0.908" "P" 0.015463 "N" 0.726384 "D" "4.33" "C" 1 10362 0.0000965065 0 11568 0 0 8626 0 0 6574 0 0 66430 0 0 906 0 0 16510 0 1 120976 0.0000082661
488654 "chr21:35821849:C>T" "KCNE1" "NM_001270405:p.Ser28Ser" "NM_001270405:c.84G>A" "EXON3" "Benign" "rs17173510" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 48 8600 0.0055814 6 4406 0.00136178 54 13006 0.00415193 0 1322 0 9 1006 0.0089 10 694 0.0144 0 1008 0 0 978 0 19 5008 0.00379393 12 10362 0.00115808 59 11568 0.00510028 5 8626 0.000579643 16 6572 0.00243457 342 66412 0.00514967 3 906 0.00331126 1 16508 0.0000605767 438 120954 0.00362121
488655 "chr21:35821850:G>A" "KCNE1" "NM_001270405:p.Ser28Leu" "NM_001270405:c.83C>T" "EXON3" "Pathogenic" "Long QT syndrome" "22429796|19716085|16379539" "rs199473350" "Pathogenicity is based on ClinVar submissions and the literature provided in PubMed." 0.066 "N" "0.006;.;0.006;.;0.006;0.006;0.006;0.006" "D;.;D;.;D;D;D;D" "0.71" "P" 0.196858 "N" 1 "N" "3.49" "C" 0 10360 0 0 11564 0 0 8622 0 0 6570 0 1 66402 0.0000150598 0 904 0 3 16508 0.00018173 4 120930 0.000033077
488656 "chr21:35821853:A>G" "KCNE1" "NM_001270405:p.Met27Thr" "NM_001270405:c.80T>C" "EXON3" "Likely benign" "rs749957298" "Pathogenicity is based on prediction data only. 0 out of 6 predictions were pathogenic." -0.223 "N" "1.0;.;1.0;.;1.0;1.0;1.0;1.0" "T;.;T;.;T;T;T;T" "0.0" "B" 0.443722 "N" 1 "N" "-5.13" "N" 0 10362 0 0 11566 0 0 8620 0 0 6566 0 0 66396 0 0 906 0 2 16508 0.000121153 2 120924 0.0000165393
488657 "chr21:35821854:T>C" "KCNE1" "NM_001270405:p.Met27Val" "NM_001270405:c.79A>G" "EXON3" "Likely benign" "rs755452452" "Pathogenicity is based on prediction data only. 0 out of 6 predictions were pathogenic." -2.329 "N" "0.834;.;0.834;.;0.834;0.834;0.834;0.834" "T;.;T;.;T;T;T;T" "0.0" "B" 0.443722 "N" 1 "N" "-8.79" "N" 0 10360 0 0 11564 0 0 8620 0 0 6562 0 1 66384 0.0000150639 0 904 0 0 16508 0 1 120902 0.00000827116
488658 "chr21:35821855:G>A" "KCNE1" "NM_001270405:p.Asn26Asn" "NM_001270405:c.78C>T" "EXON3" "Unknown significance" "rs201604169" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361 2 10358 0.000193087 0 11562 0 0 8620 0 0 6562 0 0 66376 0 0 904 0 0 16508 0 2 120890 0.000016544
488659 "chr21:35821858:G>C" "KCNE1" "NM_001270405:p.Gly25Gly" "NM_001270405:c.75C>G" "EXON3" "Unknown significance" "rs753064398" "This variant is a VUS because it does not have enough information." 0 10358 0 0 11562 0 0 8620 0 0 6556 0 1 66360 0.0000150693 0 904 0 0 16506 0 1 120866 0.00000827363
488660 "chr21:35821859:C>A" "KCNE1" "NM_001270405:p.Gly25Val" "NM_001270405:c.74G>T" "EXON3" "Pathogenic" "Atrial fibrillation, early-onset" "22471742" "Pathogenicity is based on the literature provided in PubMed." 0.037 "N" "0.048;.;0.048;.;0.048;0.048;0.048;0.048" "D;.;D;.;D;D;D;D" "0.0" "B" 0.253264 "N" 0.999992 "N" "0.61" "C"
488661 "chr21:35821862:C>T" "KCNE1" "NM_001270405:p.Gly24Asp" "NM_001270405:c.71G>A" "EXON3" "Likely benign" "rs756569224" "Pathogenicity is based on prediction data only. 1 out of 6 predictions were pathogenic." 0.892 "N" "0.138;.;0.138;.;0.138;0.138;0.138;0.138" "T;.;T;.;T;T;T;T" "0.004" "B" 0.384557 "N" 1 "N" "1.84" "C" 0 10346 0 0 11562 0 1 8620 0.000116009 0 6544 0 0 66332 0 0 904 0 0 16506 0 1 120814 0.00000827719
488662 "chr21:35821865:T>A" "KCNE1" "NM_001270405:p.Gln23Leu" "NM_001270405:c.68A>T" "EXON3" "Likely benign" "rs778331220" "Pathogenicity is based on prediction data only. 0 out of 6 predictions were pathogenic." 0.08 "N" "0.169;.;0.169;.;0.169;0.169;0.169;0.169" "T;.;T;.;T;T;T;T" "0.0" "B" 0.546037 "N" 1 "N" "-9.65" "N" 0 10346 0 0 11560 0 0 8620 0 0 6544 0 1 66318 0.0000150789 0 904 0 0 16506 0 1 120798 0.00000827828
488663 "chr21:35821874:G>A" "KCNE1" "NM_001270405:p.Thr20Ile" "NM_001270405:c.59C>T" "EXON3" "Pathogenic" "Long QT syndrome" "19322600" "rs199473349" "Pathogenicity is based on ClinVar submissions and the literature provided in PubMed." -0.362 "N" "0.399;.;0.399;.;0.399;0.399;0.399;0.399" "T;.;T;.;T;T;T;T" "0.068" "B" 0.179419 "N" 1 "N" "-1.59" "N"
488664 "chr21:35821878:C>T" "KCNE1" "NM_001270405:p.Glu19Lys" "NM_001270405:c.55G>A" "EXON3" "Likely benign" "rs183412632" "Pathogenicity is based on prediction data only. 1 out of 6 predictions were pathogenic." 0.892 "N" "0.185;.;0.185;.;0.185;0.185;0.185;0.185" "T;.;T;.;T;T;T;T" "0.001" "B" 0.756917 "N" 0.984115 "N" "2.99" "C" 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361 1 10334 0.000096768 0 11558 0 0 8620 0 0 6530 0 0 66262 0 0 902 0 0 16502 0 1 120708 0.00000828446
488665 "chr21:35821879:C>T" "KCNE1" "NM_001270405:p.Gln18Gln" "NM_001270405:c.54G>A" "EXON3" "Unknown significance" "rs149875299" "This variant is a VUS because it does not have enough information." 2 8600 0.000232558 0 4406 0 2 13006 0.000153775 0 10328 0 0 11558 0 0 8620 0 0 6528 0 4 66256 0.0000603719 0 902 0 0 16502 0 4 120694 0.0000331417
488666 "chr21:35821883:C>T" "KCNE1" "NM_001270405:p.Trp17Stop" "NM_001270405:c.50G>A" "EXON3" "Pathogenic" "Long QT syndrome" "19716085" "rs779124360" "Pathogenicity is based on the literature provided in PubMed." -0.498 "N" 0.830264 "N" 1 "D" "1.15" "C" 0 10330 0 0 11556 0 0 8620 0 0 6524 0 0 66252 0 0 900 0 1 16502 0.0000605987 1 120684 0.0000082861
488667 "chr21:35821886:A>G" "KCNE1" "NM_001270405:p.Leu16Pro" "NM_001270405:c.47T>C" "EXON3" "Pathogenic" "Long QT syndrome" "24363352" "Pathogenicity is based on the literature provided in PubMed." 1.14 "C" "0.002;.;0.002;.;0.002;0.002;0.002;0.002" "D;.;D;.;D;D;D;D" "0.993" "D" 0.369976 "N" 0.999951 "D" "3.59" "C"
488668 "chr21:35821887:G>T" "KCNE1" "NM_001270405:p.Leu16Met" "NM_001270405:c.46C>A" "EXON3" "Likely benign" "rs745951012" "Pathogenicity is based on prediction data only. 2 out of 6 predictions were pathogenic." -0.344 "N" "0.117;.;0.117;.;0.117;0.117;0.117;0.117" "T;.;T;.;T;T;T;T" "0.839" "P" 0.369976 "N" 0.997064 "N" "1.87" "C" 0 10324 0 0 11552 0 0 8620 0 0 6516 0 1 66230 0.0000150989 0 900 0 0 16502 0 1 120644 0.00000828885
488669 "chr21:35821901:G>A" "KCNE1" "NM_001270405:p.Pro11Leu" "NM_001270405:c.32C>T" "EXON3" "Likely benign" "rs771981567" "Pathogenicity is based on prediction data only. 2 out of 6 predictions were pathogenic." 0.998 "C" "0.145;.;0.145;.;0.145;0.145;0.145;0.145" "T;.;T;.;T;T;T;T" "0.054" "B" 0.353119 "N" 0.999998 "N" "3.92" "C" 0 10266 0 0 11548 0 0 8618 0 0 6494 0 0 66050 0 0 900 0 1 16496 0.0000606208 1 120372 0.00000830758
488670 "chr21:35821902:G>A" "KCNE1" "NM_001270405:p.Pro11Ser" "NM_001270405:c.31C>T" "EXON3" "Likely benign" "rs775325455" "Pathogenicity is based on prediction data only. 1 out of 6 predictions were pathogenic." 0.108 "N" "0.488;.;0.488;.;0.488;0.488;0.488;0.488" "T;.;T;.;T;T;T;T" "0.016" "B" 0.353119 "N" 1 "N" "1.95" "C" 0 10262 0 0 11546 0 0 8618 0 0 6490 0 0 66040 0 0 900 0 3 16494 0.000181884 3 120350 0.0000249273
488671 "chr21:35821903:C>T" "KCNE1" "NM_001270405:p.Thr10Thr" "NM_001270405:c.30G>A" "EXON3" "Benign" "rs187686559" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1 8600 0.000116279 0 4406 0 1 13006 0.0000768876 1 1322 0.0008 0 1006 0 0 694 0 9 1008 0.0089 0 978 0 10 5008 0.00199681 1 10258 0.0000974849 2 11546 0.00017322 39 8618 0.00452541 1 6488 0.000154131 3 66024 0.000045438 0 900 0 0 16490 0 46 120324 0.000382301
488672 "chr21:35821903:C>A" "KCNE1" "NM_001270405:p.Thr10Thr" "NM_001270405:c.30G>T" "EXON3" "Likely benign" "Cardiac arrhythmia; Arrhythmia" "rs187686559" "Pathogenicity is based on ClinVar submissions. All submitters agree with this pathogenicity."
488673 "chr21:35821904:G>A" "KCNE1" "NM_001270405:p.Thr10Met" "NM_001270405:c.29C>T" "EXON3" "Pathogenic" "Long QT syndrome" "23994779|19716085|23861362|25637381" "rs144917638" "Pathogenicity is based on ClinVar submissions and the literature provided in PubMed." -0.843 "N" "0.355;.;0.355;.;0.355;0.355;0.355;0.355" "T;.;T;.;T;T;T;T" "0.001" "B" 0.263283 "N" 1 "N" "-9.65" "N" 1 8600 0.000116279 0 4406 0 1 13006 0.0000768876 0 10246 0 3 11542 0.00025992 1 8616 0.000116063 0 6482 0 10 66018 0.000151474 1 900 0.00111111 8 16490 0.000485143 23 120294 0.000191198
488674 "chr21:35821909:C>T" "KCNE1" "NM_001270405:p.Ala8Ala" "NM_001270405:c.24G>A" "EXON3" "Benign" "rs144094344" "Pathogenicity is based on ClinVar submissions. All submitters agree with this pathogenicity." 1 8600 0.000116279 0 4406 0 1 13006 0.0000768876 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681 0 10246 0 3 11532 0.000260146 0 8608 0 0 6476 0 6 65984 0.0000909311 0 894 0 6 16482 0.000364033 15 120222 0.000124769
488675 "chr21:35821910:G>A" "KCNE1" "NM_001270405:p.Ala8Val" "NM_001270405:c.23C>T" "EXON3" "Pathogenic" "Long QT syndrome" "17341399|23994779|19716085|25637381" "rs199473348" "Pathogenicity is based on ClinVar submissions and the literature provided in PubMed." -1.766 "N" "0.034;.;0.034;.;0.034;0.034;0.034;0.034" "D;.;D;.;D;D;D;D" "0.003" "B" 0.033539 "N" 1 "N" "0.937" "C" 0 8600 0 1 4406 0.000226963 1 13006 0.0000768876 3 10242 0.000292912 0 11534 0 8 8612 0.000928936 0 6466 0 2 65976 0.0000303141 0 894 0 2 16480 0.000121359 15 120204 0.000124788
488676 "chr21:35821910:G>T" "KCNE1" "NM_001270405:p.Ala8Glu" "NM_001270405:c.23C>A" "EXON3" "Likely benign" "rs199473348" "Pathogenicity is based on prediction data only. 1 out of 6 predictions were pathogenic." -1.766 "N" "0.095;.;0.095;.;0.095;0.095;0.095;0.095" "T;.;T;.;T;T;T;T" "0.003" "B" 0.033539 "N" 1 "N" "0.937" "C" 0 10242 0 0 11534 0 0 8612 0 0 6466 0 1 65976 0.000015157 0 894 0 0 16480 0 1 120204 0.00000831919
488677 "chr21:35821913:G>A" "KCNE1" "NM_001270405:p.Thr7Ile" "NM_001270405:c.20C>T" "EXON3" "Pathogenic" "Jervell and Lange-Nielsen syndrome" "20301579|9354783" "rs28933384" "Pathogenicity is based on ClinVar submissions and the literature provided in PubMed." 0.998 "C" "0.003;.;0.003;.;0.003;0.003;0.003;0.003" "D;.;D;.;D;D;D;D" "0.999" "D" 0.000001 "D" 0.936471 "A" "4.82" "C" 0 10236 0 1 11526 0.0000867604 0 8610 0 0 6466 0 0 65966 0 0 894 0 0 16476 0 1 120174 0.00000832127
488678 "chr21:35821915:G>C" "KCNE1" "NM_001270405:p.Thr6Thr" "NM_001270405:c.18C>G" "EXON3" "Likely benign" "24033266" "rs727503102" "Pathogenicity is based on ClinVar submissions. All submitters agree with this pathogenicity."
488679 "chr21:35821918:G>T" "KCNE1" "NM_001270405:p.Asn5Lys" "NM_001270405:c.15C>A" "EXON3" "Unknown significance" "rs762400333" "This variant is a VUS because it does not have enough information." -0.29 "N" "0.005;.;0.005;.;0.005;0.005;0.005;0.005" "D;.;D;.;D;D;D;D" "1.0" "D" 0.000098 "D" 0.999999 "N" "-6.15" "N" 0 10200 0 0 11518 0 0 8606 0 0 6454 0 0 65898 0 0 894 0 1 16466 0.0000607312 1 120036 0.00000833083
488680 "chr21:35821921:->A" "KCNE1" "NM_001270405:c.12_13insT" "EXON3" "Pathogenic" "Long QT syndrome" "19716085" "Pathogenicity is based on the literature provided in PubMed."
488681 "chr21:35821921:AGAC>-" "KCNE1" "NM_001270405:c.12_17delGTCT" "EXON3" "Pathogenic" "Long QT syndrome" "19716085" "Pathogenicity is based on the literature provided in PubMed."
488682 "chr21:35821925:A>G" "KCNE1" "NM_001270405:p.Leu3Pro" "NM_001270405:c.8T>C" "EXON3" "Likely benign" "rs567021150" "Pathogenicity is based on prediction data only. 0 out of 6 predictions were pathogenic." 0.189 "N" "0.086;.;0.086;.;0.086;0.086;0.086;0.086" "T;.;T;.;T;T;T;T" "0.0" "B" 0.236152 "N" 0.995972 "N" "-2.85" "N" 0 1322 0 0 1006 0 0 694 0 0 1008 0 4 978 0.0041 4 5008 0.000798722 0 10158 0 0 11510 0 0 8608 0 0 6444 0 0 65818 0 0 894 0 17 16452 0.00103331 17 119884 0.000141804
488683 "chr21:35821928:A>T" "KCNE1" "NM_001270405:p.Ile2Asn" "NM_001270405:c.5T>A" "EXON3" "Likely benign" "rs369808496" "Pathogenicity is based on prediction data only. 0 out of 6 predictions were pathogenic." 0.116 "N" "0.258;.;0.258;.;0.258;0.258;0.258;0.258" "T;.;T;.;T;T;T;T" "0.123" "B" 0.171559 "N" 1 "N" "-1.32" "N" 1 8600 0.000116279 0 4406 0 1 13006 0.0000768876 0 10128 0 0 11506 0 0 8604 0 0 6424 0 1 65780 0.0000152022 0 894 0 0 16444 0 1 119780 0.00000834864
488684 "chr21:35821929:T>A" "KCNE1" "NM_001270405:p.Ile2Phe" "NM_001270405:c.4A>T" "EXON3" "Likely benign" "rs756727116" "Pathogenicity is based on prediction data only. 0 out of 6 predictions were pathogenic." 0.08 "N" "0.055;.;0.055;.;0.055;0.055;0.055;0.055" "T;.;T;.;T;T;T;T" "0.0" "B" 0.171559 "N" 1 "N" "-5.97" "N" 0 10126 0 0 11506 0 0 8600 0 0 6420 0 2 65764 0.0000304118 0 894 0 1 16438 0.0000608347 3 119748 0.0000250526
488685 "chr21:35821930:C>G" "KCNE1" "NM_001270405:p.Met1Ile" "NM_001270405:c.3G>C" "EXON3" "Unknown significance" "rs778280076" "This variant is a VUS because it does not have enough information." 0.892 "N" "0.012;.;0.012;.;0.012;0.012;0.012;0.012" "D;.;D;.;D;D;D;D" "0.692" "P" 0.000215 "D" 1 "D" "3.33" "C" 0 10098 0 1 11500 0.0000869565 0 8598 0 0 6412 0 0 65726 0 0 892 0 0 16430 0 1 119656 0.00000835729
488686 "chr21:35821935:T>-" "KCNE1" "NM_001270405:c.-3delA" "FIVE_PRIME_EXON" "Unknown significance" "24033266" "rs397515878" "Pathogenicity is based on ClinVar submissions. All submitters agree with this pathogenicity." 0 10086 0 1 11494 0.0000870019 0 8596 0 0 6408 0 4 65676 0.000060905 0 892 0 0 16424 0 5 119576 0.0000418144
488687 "chr21:35821937:G>T" "KCNE1" "NM_001270405:c.-5C>A" "FIVE_PRIME_EXON" "Unknown significance" "rs191334763" "This variant is a VUS because it does not have enough information." 0.691 "N" 0.999954 "N" "2.45" "C" 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361 0 10078 0 0 11490 0 9 8596 0.001047 0 6408 0 0 65616 0 0 892 0 0 16406 0 9 119486 0.0000753226
488688 "chr21:35821939:C>T" "KCNE1" "NM_001270405:c.-7G>A" "FIVE_PRIME_EXON" "Unknown significance" "rs548697948" "This variant is a VUS because it does not have enough information." 0.622 "N" 0.999991 "N" "2.25" "C" 0 1322 0 1 1006 0.001 1 694 0.0014 0 1008 0 0 978 0 2 5008 0.000399361 0 10070 0 1 11488 0.0000870474 0 8592 0 0 6398 0 0 65570 0 0 892 0 0 16402 0 1 119412 0.00000837437
488689 "chr21:35821941:T>G" "KCNE1" "NM_001270405:c.-9A>C" "FIVE_PRIME_EXON" "Unknown significance" "rs779010889" "This variant is a VUS because it does not have enough information." 0.702 "N" 0.999997 "N" "1.74" "C" 0 10066 0 1 11480 0.000087108 0 8590 0 0 6396 0 0 65542 0 0 892 0 0 16402 0 1 119368 0.00000837745
488690 "chr21:35821942:T>G" "KCNE1" "NM_001270405:c.-10A>C" "FIVE_PRIME_EXON" "Unknown significance" "rs373540781" "This variant is a VUS because it does not have enough information." 0 8600 0 1 4406 0.000226963 1 13006 0.0000768876
488691 "chr21:35821945:G>A" "KCNE1" "NM_001270405:c.-13C>T" "FIVE_PRIME_EXON" "Unknown significance" "rs745925445" "This variant is a VUS because it does not have enough information." 0 10030 0 1 11466 0.0000872144 0 8584 0 0 6378 0 0 65448 0 0 886 0 1 16392 0.0000610054 2 119184 0.0000167808
488692 "chr21:35821946:G>A" "KCNE1" "NM_001270405:c.-14C>T" "FIVE_PRIME_EXON" "Unknown significance" "rs758433996" "This variant is a VUS because it does not have enough information." 0 10014 0 9 11462 0.000785203 0 8584 0 0 6380 0 0 65424 0 0 886 0 0 16378 0 9 119128 0.000075549
488693 "chr21:35821951:A>G" "KCNE1" "NM_001270405:c.-19T>C" "FIVE_PRIME_EXON" "Unknown significance" "rs780218740" "This variant is a VUS because it does not have enough information." 1 10000 0.0001 0 11456 0 0 8576 0 0 6370 0 0 65286 0 0 888 0 0 16376 0 1 118952 0.00000840675
488694 "chr21:35821969:T>A" "KCNE1" "NM_001270405:c.-37A>T" "FIVE_PRIME_EXON" "Unknown significance" "rs746912079" "This variant is a VUS because it does not have enough information." 0 9804 0 0 11380 0 0 8544 0 0 6318 0 2 64784 0.0000308718 0 880 0 0 16298 0 2 118008 0.000016948
488695 "chr21:35821976:C>G" "KCNE1" "NM_001270405:c.-44G>C" "FIVE_PRIME_EXON" "Unknown significance" "rs768635811" "This variant is a VUS because it does not have enough information." 1 9432 0.000106022 0 11278 0 0 8480 0 0 6276 0 0 64106 0 0 876 0 0 16220 0 1 116668 0.00000857133
488696 "chr21:35821977:A>G" "KCNE1" "NM_001270405:c.-45T>C" "FIVE_PRIME_EXON" "Unknown significance" "rs776350072" "This variant is a VUS because it does not have enough information." 0 9350 0 0 11258 0 1 8482 0.000117897 0 6262 0 0 63854 0 0 874 0 0 16202 0 1 116282 0.00000859978
488697 "chr21:35821996:T>A" "KCNE1" "NM_001270405:c.-50-14A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs768905977" "This variant is a VUS because it does not have enough information."
488698 "chr21:35822019:G>A" "KCNE1" "NM_001270405:c.-50-37C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs368387585" "This variant is a VUS because it does not have enough information."
488699 "chr21:35822038:C>T" "KCNE1" "NM_001270405:c.-50-56G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs146912513" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 1 978 0.001 2 5008 0.000399361
488700 "chr21:35822039:G>A" "KCNE1" "NM_001270405:c.-50-57C>T" "FIVE_PRIME_INTRON" "Benign" "rs74448880" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 28 1322 0.0212 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 29 5008 0.00579073
488701 "chr21:35822041:A>G" "KCNE1" "NM_001270405:c.-50-59T>C" "FIVE_PRIME_INTRON" "Benign" "rs2236608" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 2 1322 0.0015 29 1006 0.0288 58 694 0.0836 49 1008 0.0486 76 978 0.0777 214 5008 0.0427316
488702 "chr21:35822042:C>T" "KCNE1" "NM_001270405:c.-50-60G>A" "FIVE_PRIME_INTRON" "Benign" "rs76165549" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 6 1006 0.006 3 694 0.0043 0 1008 0 2 978 0.002 11 5008 0.00219649
488703 "chr21:35822043:G>A" "KCNE1" "NM_001270405:c.-50-61C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs143020268" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488704 "chr21:35822052:C>T" "KCNE1" "NM_001270405:c.-50-70G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs144716120" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
488705 "chr21:35822053:G>A" "KCNE1" "NM_001270405:c.-50-71C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs184136331" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
488706 "chr21:35822081:G>A" "KCNE1" "NM_001270405:c.-50-99C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs71329067" "This variant is a VUS because it does not have enough information."
488707 "chr21:35822110:CA>-" "KCNE1" "NM_001270405:c.-50-128_-50-125delTG" "FIVE_PRIME_INTRON" "Unknown significance" "rs199679400" "This variant is a VUS because it does not have enough information."
488708 "chr21:35822110:C>T" "KCNE1" "NM_001270405:c.-50-128G>A" "FIVE_PRIME_INTRON" "Benign" "rs35811057" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 27 1322 0.0204 19 1006 0.0189 12 694 0.0173 98 1008 0.0972 89 978 0.091 245 5008 0.0489217
488709 "chr21:35822110:CA>TG" "KCNE1" "Unknown significance" "rs386818150" "This variant is a VUS because it does not have enough information."
488710 "chr21:35822111:A>G" "KCNE1" "NM_001270405:c.-50-129T>C" "FIVE_PRIME_INTRON" "Benign" "rs2236609" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 956 1322 0.7231 613 1006 0.6093 414 694 0.5965 707 1008 0.7014 611 978 0.6247 3301 5008 0.659145
488711 "chr21:35822138:C>T" "KCNE1" "NM_001270405:c.-50-156G>A" "FIVE_PRIME_INTRON" "Benign" "rs41314809" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 62 1322 0.0469 1 1006 0.001 1 694 0.0014 0 1008 0 0 978 0 64 5008 0.0127796
488712 "chr21:35822156:T>A" "KCNE1" "NM_001270405:c.-50-174A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs759262171" "This variant is a VUS because it does not have enough information."
488713 "chr21:35822175:C>A" "KCNE1" "NM_001270405:c.-50-193G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs148534369" "This variant is a VUS because it does not have enough information." 4 1322 0.003 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 5 5008 0.000998403
488714 "chr21:35822178:T>C" "KCNE1" "NM_001270405:c.-50-196A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs41314073" "This variant is a VUS because it does not have enough information."
488715 "chr21:35822260:C>T" "KCNE1" "NM_001270405:c.-50-278G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs189845908" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488716 "chr21:35822261:G>A" "KCNE1" "NM_001270405:c.-50-279C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs377324101" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361
488717 "chr21:35822270:T>C" "KCNE1" "NM_001270405:c.-50-288A>G" "FIVE_PRIME_INTRON" "Benign" "rs2070358" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 578 1322 0.4372 622 1006 0.6183 383 694 0.5519 703 1008 0.6974 509 978 0.5204 2795 5008 0.558107
488718 "chr21:35822274:T>C" "KCNE1" "NM_001270405:c.-50-292A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs556316466" "This variant is a VUS because it does not have enough information."
488719 "chr21:35822281:A>G" "KCNE1" "NM_001270405:c.-50-299T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs757781345" "This variant is a VUS because it does not have enough information."
488720 "chr21:35822297:A>G" "KCNE1" "NM_001270405:c.-50-315T>C" "FIVE_PRIME_INTRON" "Benign" "rs546704796" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 0 1008 0 17 978 0.0174 17 5008 0.00339457
488721 "chr21:35822324:G>A" "KCNE1" "NM_001270405:c.-50-342C>T" "FIVE_PRIME_INTRON" "Benign" "rs141712911" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 15 1322 0.0113 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 16 5008 0.00319489
488722 "chr21:35822368:C>T" "KCNE1" "NM_001270405:c.-50-386G>A" "FIVE_PRIME_INTRON" "Benign" "rs55857049" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 330 1322 0.2496 448 1006 0.4453 270 694 0.389 459 1008 0.4554 337 978 0.3446 1844 5008 0.368211
488723 "chr21:35822372:G>A" "KCNE1" "NM_001270405:c.-50-390C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs775321956" "This variant is a VUS because it does not have enough information."
488724 "chr21:35822375:G>A" "KCNE1" "NM_001270405:c.-50-393C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs757268442" "This variant is a VUS because it does not have enough information."
488725 "chr21:35822426:A>G" "KCNE1" "NM_001270405:c.-50-444T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs567024672" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
488726 "chr21:35822428:C>T" "KCNE1" "NM_001270405:c.-50-446G>A" "FIVE_PRIME_INTRON" "Benign" "rs115125472" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 32 1322 0.0242 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 34 5008 0.00678914
488727 "chr21:35822429:C>A" "KCNE1" "NM_001270405:c.-50-447G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs762529453" "This variant is a VUS because it does not have enough information."
488728 "chr21:35822444:CCTTCTC>-" "KCNE1" "NM_001270405:c.-50-462_-50-454delGAGAAGG" "FIVE_PRIME_INTRON" "Unknown significance" "rs534753241" "This variant is a VUS because it does not have enough information." 3 1322 0.0023 0 1006 0 0 694 0 1 1008 0.001 0 978 0 4 5008 0.000798722
488729 "chr21:35822447:TTCTCCCC>-" "KCNE1" "NM_001270405:c.-50-465_-50-456delGGGGAGAA" "FIVE_PRIME_INTRON" "Unknown significance" "rs796756275" "This variant is a VUS because it does not have enough information."
488730 "chr21:35822450:C>-" "KCNE1" "NM_001270405:c.-50-468delG" "FIVE_PRIME_INTRON" "Unknown significance" "rs773346489" "This variant is a VUS because it does not have enough information."
488731 "chr21:35822460:T>C" "KCNE1" "NM_001270405:c.-50-478A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs780932875" "This variant is a VUS because it does not have enough information."
488732 "chr21:35822476:T>C" "KCNE1" "NM_001270405:c.-50-494A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs763646851" "This variant is a VUS because it does not have enough information."
488733 "chr21:35822505:A>G" "KCNE1" "NM_001270405:c.-50-523T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs745728634" "This variant is a VUS because it does not have enough information."
488734 "chr21:35822517:T>C" "KCNE1" "NM_001270405:c.-50-535A>G" "FIVE_PRIME_INTRON" "Benign" "rs79687087" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1 1322 0.0008 32 1006 0.0318 11 694 0.0159 0 1008 0 5 978 0.0051 49 5008 0.00978435
488735 "chr21:35822525:C>T" "KCNE1" "NM_001270405:c.-50-543G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs779046989" "This variant is a VUS because it does not have enough information."
488736 "chr21:35822535:->A" "KCNE1" "NM_001270405:c.-50-553_-50-552insT" "FIVE_PRIME_INTRON" "Benign" "rs542949487" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 5 1008 0.005 0 978 0 5 5008 0.000998403
488737 "chr21:35822546:C>G" "KCNE1" "NM_001270405:c.-50-564G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs560346850" "This variant is a VUS because it does not have enough information."
488738 "chr21:35822547:G>A" "KCNE1" "NM_001270405:c.-50-565C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs571191198" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
488739 "chr21:35822571:C>T" "KCNE1" "NM_001270405:c.-50-589G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs192793334" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488740 "chr21:35822572:A>G" "KCNE1" "NM_001270405:c.-50-590T>C" "FIVE_PRIME_INTRON" "Benign" "rs1547356" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1213 1322 0.9175 713 1006 0.7087 500 694 0.7205 892 1008 0.8849 732 978 0.7485 4050 5008 0.808706
488741 "chr21:35822578:T>C" "KCNE1" "NM_001270405:c.-50-596A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs572244103" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488742 "chr21:35822610:G>A" "KCNE1" "NM_001270405:c.-50-628C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs750228467" "This variant is a VUS because it does not have enough information."
488743 "chr21:35822615:G>A" "KCNE1" "NM_001270405:c.-50-633C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs761059435" "This variant is a VUS because it does not have enough information."
488744 "chr21:35822620:A>G" "KCNE1" "NM_001270405:c.-50-638T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs536499033" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
488745 "chr21:35822655:T>C" "KCNE1" "NM_001270405:c.-50-673A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs771636735" "This variant is a VUS because it does not have enough information."
488746 "chr21:35822687:A>G" "KCNE1" "NM_001270405:c.-50-705T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs150559473" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 3 1008 0.003 0 978 0 3 5008 0.000599042
488747 "chr21:35822696:C>T" "KCNE1" "NM_001270405:c.-50-714G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs777124481" "This variant is a VUS because it does not have enough information."
488748 "chr21:35822697:G>A" "KCNE1" "NM_001270405:c.-50-715C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs574193325" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488749 "chr21:35822698:T>C" "KCNE1" "NM_001270405:c.-50-716A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs759925104" "This variant is a VUS because it does not have enough information."
488750 "chr21:35822758:T>C" "KCNE1" "NM_001270405:c.-50-776A>G" "FIVE_PRIME_INTRON" "Benign" "rs1547357" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 352 1322 0.2663 657 1006 0.6531 254 694 0.366 524 1008 0.5198 660 978 0.6748 2447 5008 0.488618
488751 "chr21:35822801:C>A" "KCNE1" "NM_001270405:c.-50-819G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs752254384" "This variant is a VUS because it does not have enough information."
488752 "chr21:35822809:C>A" "KCNE1" "NM_001270405:c.-50-827G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs762689598" "This variant is a VUS because it does not have enough information."
488753 "chr21:35822811:T>C" "KCNE1" "NM_001270405:c.-50-829A>G" "FIVE_PRIME_INTRON" "Benign" "rs139593695" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 9 1008 0.0089 0 978 0 9 5008 0.00179712
488754 "chr21:35822842:T>C" "KCNE1" "NM_001270405:c.-50-860A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs577992769" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
488755 "chr21:35822872:G>C" "KCNE1" "NM_001270405:c.-50-890C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs763490771" "This variant is a VUS because it does not have enough information."
488756 "chr21:35822876:C>T" "KCNE1" "NM_001270405:c.-50-894G>A" "FIVE_PRIME_INTRON" "Benign" "rs77746074" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 36 694 0.0519 11 1008 0.0109 0 978 0 47 5008 0.00938498
488757 "chr21:35822877:G>A" "KCNE1" "NM_001270405:c.-50-895C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs757181669" "This variant is a VUS because it does not have enough information."
488758 "chr21:35822934:T>C" "KCNE1" "NM_001270405:c.-50-952A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs560887646" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
488759 "chr21:35822939:C>T" "KCNE1" "NM_001270405:c.-50-957G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs763078491" "This variant is a VUS because it does not have enough information."
488760 "chr21:35822948:A>G" "KCNE1" "NM_001270405:c.-50-966T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs184847190" "This variant is a VUS because it does not have enough information."
488761 "chr21:35822962:C>T" "KCNE1" "NM_001270405:c.-50-980G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs375410503" "This variant is a VUS because it does not have enough information."
488762 "chr21:35822982:A>G" "KCNE1" "NM_001270405:c.-50-1000T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs143459823" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
488763 "chr21:35822984:C>T" "KCNE1" "NM_001270405:c.-50-1002G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs117101012" "This variant is a VUS because it does not have enough information." 0 1322 0 2 1006 0.002 1 694 0.0014 0 1008 0 0 978 0 3 5008 0.000599042
488764 "chr21:35822985:G>A" "KCNE1" "NM_001270405:c.-50-1003C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs750372476" "This variant is a VUS because it does not have enough information."
488765 "chr21:35822990:A>T" "KCNE1" "NM_001270405:c.-50-1008T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs566442083" "This variant is a VUS because it does not have enough information."
488766 "chr21:35823005:T>C" "KCNE1" "NM_001270405:c.-50-1023A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs13052081" "This variant is a VUS because it does not have enough information." 0 1322 0 4 1006 0.004 2 694 0.0029 0 1008 0 0 978 0 6 5008 0.00119808
488767 "chr21:35823025:G>A" "KCNE1" "NM_001270405:c.-50-1043C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs528726006" "This variant is a VUS because it does not have enough information."
488768 "chr21:35823040:A>G" "KCNE1" "NM_001270405:c.-50-1058T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs531324634" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488769 "chr21:35823045:G>T" "KCNE1" "NM_001270405:c.-50-1063C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs368119919" "This variant is a VUS because it does not have enough information."
488770 "chr21:35823075:->GGTTT" "KCNE1" "NM_001270405:c.-50-1093_-50-1092insAAACC" "FIVE_PRIME_INTRON" "Unknown significance" "rs763024561" "This variant is a VUS because it does not have enough information."
488771 "chr21:35823131:->A" "KCNE1" "NM_001270405:c.-50-1149_-50-1148insT" "FIVE_PRIME_INTRON" "Unknown significance" "rs564918188" "This variant is a VUS because it does not have enough information."
488772 "chr21:35823139:C>A" "KCNE1" "NM_001270405:c.-50-1157G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs758652867" "This variant is a VUS because it does not have enough information."
488773 "chr21:35823142:G>C" "KCNE1" "NM_001270405:c.-50-1160C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs549491302" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488774 "chr21:35823150:->TTTA" "KCNE1" "NM_001270405:c.-50-1168_-50-1167insTAAA" "FIVE_PRIME_INTRON" "Unknown significance" "rs142537229" "This variant is a VUS because it does not have enough information."
488775 "chr21:35823150:->TTTATTTA" "KCNE1" "NM_001270405:c.-50-1168_-50-1167insTAAATAAA" "FIVE_PRIME_INTRON" "Unknown significance" "rs142537229" "This variant is a VUS because it does not have enough information."
488776 "chr21:35823150:->TTTATTTATTTA" "KCNE1" "NM_001270405:c.-50-1168_-50-1167insTAAATAAATAAA" "FIVE_PRIME_INTRON" "Unknown significance" "rs142537229" "This variant is a VUS because it does not have enough information."
488777 "chr21:35823150:->TTTATTTATTTATTTA" "KCNE1" "NM_001270405:c.-50-1168_-50-1167insTAAATAAATAAATAAA" "FIVE_PRIME_INTRON" "Unknown significance" "rs142537229" "This variant is a VUS because it does not have enough information."
488778 "chr21:35823165:->TTTATTTATTTATTTATTTATTTATTTA" "KCNE1" "NM_001270405:c.-50-1183_-50-1182insTAAATAAATAAATAAATAAATAAATAAA" "FIVE_PRIME_INTRON" "Unknown significance" "rs572893413" "This variant is a VUS because it does not have enough information." 3 1322 0.0023 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 4 5008 0.000798722
488779 "chr21:35823171:->TTA" "KCNE1" "NM_001270405:c.-50-1189_-50-1188insTAA" "FIVE_PRIME_INTRON" "Unknown significance" "rs533344630" "This variant is a VUS because it does not have enough information." 3 1322 0.0023 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 4 5008 0.000798722
488780 "chr21:35823178:G>T" "KCNE1" "NM_001270405:c.-50-1196C>A" "FIVE_PRIME_INTRON" "Benign" "rs571237292" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 27 1322 0.0204 2 1006 0.002 1 694 0.0014 21 1008 0.0208 3 978 0.0031 54 5008 0.0107827
488781 "chr21:35823189:A>G" "KCNE1" "NM_001270405:c.-50-1207T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs779927720" "This variant is a VUS because it does not have enough information."
488782 "chr21:35823233:G>A" "KCNE1" "NM_001270405:c.-50-1251C>T" "FIVE_PRIME_INTRON" "Benign" "rs181526786" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 26 1322 0.0197 0 1006 0 0 694 0 0 1008 0 0 978 0 26 5008 0.00519169
488783 "chr21:35823236:G>C" "KCNE1" "NM_001270405:c.-50-1254C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs79713292" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361
488784 "chr21:35823292:A>T" "KCNE1" "NM_001270405:c.-50-1310T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs565969740" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488785 "chr21:35823298:C>T" "KCNE1" "NM_001270405:c.-50-1316G>A" "FIVE_PRIME_INTRON" "Benign" "rs73363368" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 336 1322 0.2542 1 1006 0.001 14 694 0.0202 0 1008 0 0 978 0 351 5008 0.0700879
488786 "chr21:35823299:G>A" "KCNE1" "NM_001270405:c.-50-1317C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs550628599" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
488787 "chr21:35823314:C>A" "KCNE1" "NM_001270405:c.-50-1332G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs186504334" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 2 694 0.0029 0 1008 0 0 978 0 3 5008 0.000599042
488788 "chr21:35823355:C>T" "KCNE1" "NM_001270405:c.-50-1373G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs189334958" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 2 694 0.0029 0 1008 0 0 978 0 3 5008 0.000599042
488789 "chr21:35823360:C>T" "KCNE1" "NM_001270405:c.-50-1378G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs747069518" "This variant is a VUS because it does not have enough information."
488790 "chr21:35823364:C>T" "KCNE1" "NM_001270405:c.-50-1382G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs796504384" "This variant is a VUS because it does not have enough information."
488791 "chr21:35823429:C>T" "KCNE1" "NM_001270405:c.-50-1447G>A" "FIVE_PRIME_INTRON" "Benign" "rs78325099" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 7 1322 0.0053 0 1006 0 0 694 0 0 1008 0 0 978 0 7 5008 0.00139776
488792 "chr21:35823435:C>T" "KCNE1" "NM_001270405:c.-50-1453G>A" "FIVE_PRIME_INTRON" "Benign" "rs139064738" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 4 1006 0.004 0 694 0 1 1008 0.001 11 978 0.0112 16 5008 0.00319489
488793 "chr21:35823437:C>T" "KCNE1" "NM_001270405:c.-50-1455G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs545387252" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488794 "chr21:35823475:C>T" "KCNE1" "NM_001270405:c.-50-1493G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs747175282" "This variant is a VUS because it does not have enough information."
488795 "chr21:35823477:A>G" "KCNE1" "NM_001270405:c.-50-1495T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs143990862" "This variant is a VUS because it does not have enough information."
488796 "chr21:35823494:G>A" "KCNE1" "NM_001270405:c.-50-1512C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs553840540" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
488797 "chr21:35823520:C>G" "KCNE1" "NM_001270405:c.-50-1538G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs796616448" "This variant is a VUS because it does not have enough information."
488798 "chr21:35823545:C>T" "KCNE1" "NM_001270405:c.-50-1563G>A" "FIVE_PRIME_INTRON" "Benign" "rs144926582" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 7 1322 0.0053 0 1006 0 0 694 0 0 1008 0 0 978 0 7 5008 0.00139776
488799 "chr21:35823549:T>G" "KCNE1" "NM_001270405:c.-50-1567A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs542882777" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
488800 "chr21:35823564:C>T" "KCNE1" "NM_001270405:c.-50-1582G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs771150359" "This variant is a VUS because it does not have enough information."
488801 "chr21:35823565:G>A" "KCNE1" "NM_001270405:c.-50-1583C>T" "FIVE_PRIME_INTRON" "Benign" "rs149057080" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 22 1322 0.0166 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 23 5008 0.00459265
488802 "chr21:35823577:C>T" "KCNE1" "NM_001270405:c.-50-1595G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs372992647" "This variant is a VUS because it does not have enough information."
488803 "chr21:35823580:C>T" "KCNE1" "NM_001270405:c.-50-1598G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs531819566" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
488804 "chr21:35823589:T>A" "KCNE1" "NM_001270405:c.-50-1607A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs796408079" "This variant is a VUS because it does not have enough information."
488805 "chr21:35823606:G>A" "KCNE1" "NM_001270405:c.-50-1624C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs374992913" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
488806 "chr21:35823641:C>T" "KCNE1" "NM_001270405:c.-50-1659G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs143104679" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
488807 "chr21:35823670:G>A" "KCNE1" "NM_001270405:c.-50-1688C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs777214391" "This variant is a VUS because it does not have enough information."
488808 "chr21:35823686:C>T" "KCNE1" "NM_001270405:c.-50-1704G>A" "FIVE_PRIME_INTRON" "Benign" "rs78167140" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 218 1322 0.1649 0 1006 0 9 694 0.013 1 1008 0.001 0 978 0 228 5008 0.0455272
488809 "chr21:35823687:G>A" "KCNE1" "NM_001270405:c.-50-1705C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs569212752" "This variant is a VUS because it does not have enough information."
488810 "chr21:35823691:G>T" "KCNE1" "NM_001270405:c.-50-1709C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs770236610" "This variant is a VUS because it does not have enough information."
488811 "chr21:35823732:A>G" "KCNE1" "NM_001270405:c.-50-1750T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs547381607" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
488812 "chr21:35823742:C>T" "KCNE1" "NM_001270405:c.-50-1760G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs151084570" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
488813 "chr21:35823749:G>A" "KCNE1" "NM_001270405:c.-50-1767C>T" "FIVE_PRIME_INTRON" "Benign" "rs73363372" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 82 1322 0.062 3 1006 0.003 1 694 0.0014 0 1008 0 1 978 0.001 87 5008 0.0173722
488814 "chr21:35823750:C>T" "KCNE1" "NM_001270405:c.-50-1768G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs180915143" "This variant is a VUS because it does not have enough information." 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042
488815 "chr21:35823778:C>T" "KCNE1" "NM_001270405:c.-50-1796G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs534211905" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 1 978 0.001 2 5008 0.000399361
488816 "chr21:35823779:G>A" "KCNE1" "NM_001270405:c.-50-1797C>T" "FIVE_PRIME_INTRON" "Benign" "rs11088283" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1012 1322 0.7655 506 1006 0.503 433 694 0.6239 667 1008 0.6617 496 978 0.5072 3114 5008 0.621805
488817 "chr21:35823783:C>G" "KCNE1" "NM_001270405:c.-50-1801G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs570434552" "This variant is a VUS because it does not have enough information."
488818 "chr21:35823784:G>A" "KCNE1" "NM_001270405:c.-50-1802C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs558420000" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488819 "chr21:35823786:C>T" "KCNE1" "NM_001270405:c.-50-1804G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs571722183" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488820 "chr21:35823808:G>T" "KCNE1" "NM_001270405:c.-50-1826C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs796360305" "This variant is a VUS because it does not have enough information."
488821 "chr21:35823809:G>A" "KCNE1" "NM_001270405:c.-50-1827C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs185768973" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
488822 "chr21:35823895:T>G" "KCNE1" "NM_001270405:c.-50-1913A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs142575425" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361
488823 "chr21:35823914:T>C" "KCNE1" "NM_001270405:c.-50-1932A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs761252837" "This variant is a VUS because it does not have enough information."
488824 "chr21:35823922:A>C" "KCNE1" "NM_001270405:c.-50-1940T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs41314811" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488825 "chr21:35823928:T>C" "KCNE1" "NM_001270405:c.-50-1946A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs767016082" "This variant is a VUS because it does not have enough information."
488826 "chr21:35823937:C>A" "KCNE1" "NM_001270405:c.-50-1955G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs191018795" "This variant is a VUS because it does not have enough information."
488827 "chr21:35823971:C>G" "KCNE1" "NM_001270405:c.-50-1989G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs374742811" "This variant is a VUS because it does not have enough information."
488828 "chr21:35823998:C>G" "KCNE1" "NM_001270405:c.-50-2016G>C" "FIVE_PRIME_INTRON" "Benign" "rs928740" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1026 1322 0.7761 676 1006 0.672 533 694 0.768 811 1008 0.8046 666 978 0.681 3712 5008 0.741214
488829 "chr21:35824043:C>T" "KCNE1" "NM_001270405:c.-50-2061G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs78721772" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 3 978 0.0031 3 5008 0.000599042
488830 "chr21:35824045:C>T" "KCNE1" "NM_001270405:c.-50-2063G>A" "FIVE_PRIME_INTRON" "Benign" "rs146895574" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 8 1008 0.0079 0 978 0 8 5008 0.00159744
488831 "chr21:35824056:C>T" "KCNE1" "NM_001270405:c.-50-2074G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs756063899" "This variant is a VUS because it does not have enough information."
488832 "chr21:35824082:C>T" "KCNE1" "NM_001270405:c.-50-2100G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs543999411" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488833 "chr21:35824089:A>T" "KCNE1" "NM_001270405:c.-50-2107T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs79799835" "This variant is a VUS because it does not have enough information."
488834 "chr21:35824107:T>A" "KCNE1" "NM_001270405:c.-50-2125A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs766061734" "This variant is a VUS because it does not have enough information."
488835 "chr21:35824119:C>T" "KCNE1" "NM_001270405:c.-50-2137G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs565298241" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
488836 "chr21:35824133:C>A" "KCNE1" "NM_001270405:c.-50-2151G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs753736857" "This variant is a VUS because it does not have enough information."
488837 "chr21:35824167:C>T" "KCNE1" "NM_001270405:c.-50-2185G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs375372611" "This variant is a VUS because it does not have enough information."
488838 "chr21:35824179:C>T" "KCNE1" "NM_001270405:c.-50-2197G>A" "FIVE_PRIME_INTRON" "Benign" "rs74490375" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1 1322 0.0008 16 1006 0.0159 10 694 0.0144 0 1008 0 0 978 0 27 5008 0.00539137
488839 "chr21:35824224:G>T" "KCNE1" "NM_001270405:c.-50-2242C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs41312373" "This variant is a VUS because it does not have enough information."
488840 "chr21:35824225:C>T" "KCNE1" "NM_001270405:c.-50-2243G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs41312375" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 2 5008 0.000399361
488841 "chr21:35824230:T>C" "KCNE1" "NM_001270405:c.-50-2248A>G" "FIVE_PRIME_INTRON" "Benign" "rs928741" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 877 1322 0.6634 680 1006 0.6759 524 694 0.755 814 1008 0.8075 668 978 0.683 3563 5008 0.711462
488842 "chr21:35824302:C>A" "KCNE1" "NM_001270405:c.-50-2320G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs186462230" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
488843 "chr21:35824312:C>G" "KCNE1" "NM_001270405:c.-50-2330G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs79318383" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488844 "chr21:35824365:C>T" "KCNE1" "NM_001270405:c.-50-2383G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs190615998" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
488845 "chr21:35824370:T>C" "KCNE1" "NM_001270405:c.-50-2388A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs182792519" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361
488846 "chr21:35824398:A>G" "KCNE1" "NM_001270405:c.-50-2416T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs139369274" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488847 "chr21:35824399:T>C" "KCNE1" "NM_001270405:c.-50-2417A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs187783701" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
488848 "chr21:35824400:G>A" "KCNE1" "NM_001270405:c.-50-2418C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs141492141" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488849 "chr21:35824404:C>T" "KCNE1" "NM_001270405:c.-50-2422G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs547606668" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
488850 "chr21:35824409:T>A" "KCNE1" "NM_001270405:c.-50-2427A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs746356194" "This variant is a VUS because it does not have enough information."
488851 "chr21:35824411:C>T" "KCNE1" "NM_001270405:c.-50-2429G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs565823823" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
488852 "chr21:35824467:C>T" "KCNE1" "NM_001270405:c.-50-2485G>A" "FIVE_PRIME_INTRON" "Benign" "rs192302919" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 0 1008 0 14 978 0.0143 14 5008 0.00279553
488853 "chr21:35824467:C>A" "KCNE1" "NM_001270405:c.-50-2485G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs192302919" "This variant is a VUS because it does not have enough information."
488854 "chr21:35824468:G>A" "KCNE1" "NM_001270405:c.-50-2486C>T" "FIVE_PRIME_INTRON" "Benign" "rs9976263" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 890 1322 0.6732 675 1006 0.671 529 694 0.7622 795 1008 0.7887 624 978 0.638 3513 5008 0.701478
488855 "chr21:35824505:C>T" "KCNE1" "NM_001270405:c.-50-2523G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs761298346" "This variant is a VUS because it does not have enough information."
488856 "chr21:35824506:G>A" "KCNE1" "NM_001270405:c.-50-2524C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs376348609" "This variant is a VUS because it does not have enough information."
488857 "chr21:35824551:C>T" "KCNE1" "NM_001270405:c.-50-2569G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs749719691" "This variant is a VUS because it does not have enough information."
488858 "chr21:35824576:T>C" "KCNE1" "NM_001270405:c.-50-2594A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs576339671" "This variant is a VUS because it does not have enough information." 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042
488859 "chr21:35824584:G>A" "KCNE1" "NM_001270405:c.-50-2602C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs768913177" "This variant is a VUS because it does not have enough information."
488860 "chr21:35824592:CT>-" "KCNE1" "NM_001270405:c.-50-2610_-50-2607delAG" "FIVE_PRIME_INTRON" "Unknown significance" "rs753085648" "This variant is a VUS because it does not have enough information."
488861 "chr21:35824598:T>C" "KCNE1" "NM_001270405:c.-50-2616A>G" "FIVE_PRIME_INTRON" "Benign" "rs113741921" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 70 1322 0.053 1 1006 0.001 1 694 0.0014 0 1008 0 0 978 0 72 5008 0.014377
488862 "chr21:35824602:T>C" "KCNE1" "NM_001270405:c.-50-2620A>G" "FIVE_PRIME_INTRON" "Benign" "rs2834486" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 80 1322 0.0605 237 1006 0.2356 120 694 0.1729 97 1008 0.0962 185 978 0.1892 719 5008 0.14357
488863 "chr21:35824627:C>T" "KCNE1" "NM_001270405:c.-50-2645G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs766962960" "This variant is a VUS because it does not have enough information."
488864 "chr21:35824695:C>T" "KCNE1" "NM_001270405:c.-50-2713G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs577395486" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 3 5008 0.000599042
488865 "chr21:35824705:G>T" "KCNE1" "NM_001270405:c.-50-2723C>A" "FIVE_PRIME_INTRON" "Benign" "rs150404652" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 8 1008 0.0079 0 978 0 8 5008 0.00159744
488866 "chr21:35824713:C>T" "KCNE1" "NM_001270405:c.-50-2731G>A" "FIVE_PRIME_INTRON" "Benign" "rs115550044" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 31 1322 0.0234 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 32 5008 0.00638978
488867 "chr21:35824714:G>A" "KCNE1" "NM_001270405:c.-50-2732C>T" "FIVE_PRIME_INTRON" "Benign" "rs7276763" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 35 1322 0.0265 69 1006 0.0686 49 694 0.0706 127 1008 0.126 56 978 0.0573 336 5008 0.0670927
488868 "chr21:35824742:T>C" "KCNE1" "NM_001270405:c.-50-2760A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs117324528" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 1 694 0.0014 0 1008 0 0 978 0 2 5008 0.000399361
488869 "chr21:35824747:C>T" "KCNE1" "NM_001270405:c.-50-2765G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs756072021" "This variant is a VUS because it does not have enough information."
488870 "chr21:35824762:A>T" "KCNE1" "NM_001270405:c.-50-2780T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs766401796" "This variant is a VUS because it does not have enough information."
488871 "chr21:35824788:G>A" "KCNE1" "NM_001270405:c.-50-2806C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs563239915" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488872 "chr21:35824817:->A" "KCNE1" "NM_001270405:c.-50-2835_-50-2834insT" "FIVE_PRIME_INTRON" "Unknown significance" "rs34357944" "This variant is a VUS because it does not have enough information."
488873 "chr21:35824819:T>C" "KCNE1" "NM_001270405:c.-50-2837A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs184027398" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361
488874 "chr21:35824826:ATGCCA>-" "KCNE1" "NM_001270405:c.-50-2844_-50-2837delTGGCAT" "FIVE_PRIME_INTRON" "Unknown significance" "rs564059583" "This variant is a VUS because it does not have enough information."
488875 "chr21:35824833:T>-" "KCNE1" "NM_001270405:c.-50-2851delA" "FIVE_PRIME_INTRON" "Unknown significance" "rs576787724" "This variant is a VUS because it does not have enough information."
488876 "chr21:35824844:C>T" "KCNE1" "NM_001270405:c.-50-2862G>A" "FIVE_PRIME_INTRON" "Benign" "rs115033698" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 38 1322 0.0287 0 1006 0 3 694 0.0043 0 1008 0 0 978 0 41 5008 0.0081869
488877 "chr21:35824851:CTAA>-" "KCNE1" "NM_001270405:c.-50-2869_-50-2864delTTAG" "FIVE_PRIME_INTRON" "Unknown significance" "rs766125908" "This variant is a VUS because it does not have enough information."
488878 "chr21:35824857:G>A" "KCNE1" "NM_001270405:c.-50-2875C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs753637933" "This variant is a VUS because it does not have enough information."
488879 "chr21:35824872:A>C" "KCNE1" "NM_001270405:c.-50-2890T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs796992642" "This variant is a VUS because it does not have enough information."
488880 "chr21:35824935:C>A" "KCNE1" "NM_001270405:c.-50-2953G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs138173462" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488881 "chr21:35824959:G>A" "KCNE1" "NM_001270405:c.-50-2977C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs370249500" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 2 978 0.002 4 5008 0.000798722
488882 "chr21:35824960:C>G" "KCNE1" "NM_001270405:c.-50-2978G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs546768832" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
488883 "chr21:35824984:C>G" "KCNE1" "NM_001270405:c.-50-3002G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs565837770" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 3 978 0.0031 3 5008 0.000599042
488884 "chr21:35824990:C>T" "KCNE1" "NM_001270405:c.-50-3008G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs149587446" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488885 "chr21:35825001:G>C" "KCNE1" "NM_001270405:c.-50-3019C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs544204687" "This variant is a VUS because it does not have enough information."
488886 "chr21:35825004:C>A" "KCNE1" "NM_001270405:c.-50-3022G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs548194836" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
488887 "chr21:35825011:A>C" "KCNE1" "NM_001270405:c.-50-3029T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs569689385" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488888 "chr21:35825037:T>-" "KCNE1" "NM_001270405:c.-50-3055delA" "FIVE_PRIME_INTRON" "Unknown significance" "rs150518931" "This variant is a VUS because it does not have enough information."
488889 "chr21:35825065:G>A" "KCNE1" "NM_001270405:c.-50-3083C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs537434923" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
488890 "chr21:35825097:A>G" "KCNE1" "NM_001270405:c.-50-3115T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs562950743" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488891 "chr21:35825100:A>C" "KCNE1" "NM_001270405:c.-50-3118T>G" "FIVE_PRIME_INTRON" "Benign" "rs1012945" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1028 1322 0.7776 680 1006 0.6759 529 694 0.7622 803 1008 0.7966 626 978 0.6401 3666 5008 0.732029
488892 "chr21:35825101:C>G" "KCNE1" "NM_001270405:c.-50-3119G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs534955075" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
488893 "chr21:35825122:C>T" "KCNE1" "NM_001270405:c.-50-3140G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs367846012" "This variant is a VUS because it does not have enough information."
488894 "chr21:35825132:G>A" "KCNE1" "NM_001270405:c.-50-3150C>T" "FIVE_PRIME_INTRON" "Benign" "rs553563046" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1 1322 0.0008 0 1006 0 1 694 0.0014 0 1008 0 12 978 0.0123 14 5008 0.00279553
488895 "chr21:35825134:G>A" "KCNE1" "NM_001270405:c.-50-3152C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs187727370" "This variant is a VUS because it does not have enough information." 6 1322 0.0045 0 1006 0 0 694 0 0 1008 0 0 978 0 6 5008 0.00119808
488896 "chr21:35825142:G>A" "KCNE1" "NM_001270405:c.-50-3160C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs192664831" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
488897 "chr21:35825143:C>T" "KCNE1" "NM_001270405:c.-50-3161G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs563350015" "This variant is a VUS because it does not have enough information." 0 1322 0 2 1006 0.002 0 694 0 0 1008 0 1 978 0.001 3 5008 0.000599042
488898 "chr21:35825207:T>C" "KCNE1" "NM_001270405:c.-50-3225A>G" "FIVE_PRIME_INTRON" "Benign" "rs113165517" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 13 1322 0.0098 0 1006 0 0 694 0 0 1008 0 0 978 0 13 5008 0.00259585
488899 "chr21:35825215:G>C" "KCNE1" "NM_001270405:c.-50-3233C>G" "FIVE_PRIME_INTRON" "Benign" "rs7277511" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 255 1322 0.1929 69 1006 0.0686 59 694 0.085 135 1008 0.1339 56 978 0.0573 574 5008 0.114617
488900 "chr21:35825218:T>C" "KCNE1" "NM_001270405:c.-50-3236A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs564267809" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
488901 "chr21:35825229:G>C" "KCNE1" "NM_001270405:c.-50-3247C>G" "FIVE_PRIME_INTRON" "Benign" "rs115589835" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 29 1322 0.0219 0 1006 0 0 694 0 0 1008 0 0 978 0 29 5008 0.00579073
488902 "chr21:35825239:C>T" "KCNE1" "NM_001270405:c.-50-3257G>A" "FIVE_PRIME_INTRON" "Benign" "rs59325379" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 29 1322 0.0219 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 31 5008 0.0061901
488903 "chr21:35825265:C>T" "KCNE1" "NM_001270405:c.-50-3283G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs561512520" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 3 1008 0.003 0 978 0 3 5008 0.000599042
488904 "chr21:35825266:A>G" "KCNE1" "NM_001270405:c.-50-3284T>C" "FIVE_PRIME_INTRON" "Benign" "rs1012944" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1184 1322 0.8956 680 1006 0.6759 537 694 0.7738 821 1008 0.8145 668 978 0.683 3890 5008 0.776757
488905 "chr21:35825273:T>C" "KCNE1" "NM_001270405:c.-50-3291A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs756564389" "This variant is a VUS because it does not have enough information."
488906 "chr21:35825280:C>T" "KCNE1" "NM_001270405:c.-50-3298G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs548307424" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
488907 "chr21:35825281:G>A" "KCNE1" "NM_001270405:c.-50-3299C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs141763265" "This variant is a VUS because it does not have enough information."
488908 "chr21:35825350:G>T" "KCNE1" "NM_001270405:c.-50-3368C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs527910661" "This variant is a VUS because it does not have enough information."
488909 "chr21:35825384:C>T" "KCNE1" "NM_001270405:c.-50-3402G>A" "FIVE_PRIME_INTRON" "Benign" "rs146259006" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 7 1322 0.0053 0 1006 0 0 694 0 0 1008 0 0 978 0 7 5008 0.00139776
488910 "chr21:35825406:C>A" "KCNE1" "NM_001270405:c.-50-3424G>T" "FIVE_PRIME_INTRON" "Benign" "rs41314813" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 72 1322 0.0545 1 1006 0.001 1 694 0.0014 0 1008 0 0 978 0 74 5008 0.0147764
488911 "chr21:35825408:T>C" "KCNE1" "NM_001270405:c.-50-3426A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs552539806" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
488912 "chr21:35825410:G>C" "KCNE1" "NM_001270405:c.-50-3428C>G" "FIVE_PRIME_INTRON" "Benign" "rs7277816" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 399 1322 0.3018 238 1006 0.2366 133 694 0.1916 94 1008 0.0933 178 978 0.182 1042 5008 0.208067
488913 "chr21:35825419:C>T" "KCNE1" "NM_001270405:c.-50-3437G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs535289764" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
488914 "chr21:35825425:T>C" "KCNE1" "NM_001270405:c.-50-3443A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs41314815" "This variant is a VUS because it does not have enough information."
488915 "chr21:35825434:G>A" "KCNE1" "NM_001270405:c.-50-3452C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs779268338" "This variant is a VUS because it does not have enough information."
488916 "chr21:35825445:A>G" "KCNE1" "NM_001270405:c.-50-3463T>C" "FIVE_PRIME_INTRON" "Benign" "rs553624744" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 0 1008 0 25 978 0.0256 25 5008 0.00499201
488917 "chr21:35825450:C>T" "KCNE1" "NM_001270405:c.-50-3468G>A" "FIVE_PRIME_INTRON" "Benign" "rs7277582" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 251 1322 0.1899 0 1006 0 10 694 0.0144 0 1008 0 0 978 0 261 5008 0.0521166
488918 "chr21:35825451:G>A" "KCNE1" "NM_001270405:c.-50-3469C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs548506980" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 4 978 0.0041 4 5008 0.000798722
488919 "chr21:35825472:G>T" "KCNE1" "NM_001270405:c.-50-3490C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs557130617" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
488920 "chr21:35825495:C>T" "KCNE1" "NM_001270405:c.-50-3513G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs575292404" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
488921 "chr21:35825517:C>G" "KCNE1" "NM_001270405:c.-50-3535G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs368177613" "This variant is a VUS because it does not have enough information."
488922 "chr21:35825518:C>T" "KCNE1" "NM_001270405:c.-50-3536G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs545481951" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
488923 "chr21:35825544:C>T" "KCNE1" "NM_001270405:c.-50-3562G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs557693274" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
488924 "chr21:35825583:G>A" "KCNE1" "NM_001270405:c.-50-3601C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs549508352" "This variant is a VUS because it does not have enough information."
488925 "chr21:35825653:T>G" "KCNE1" "NM_001270405:c.-50-3671A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs772699044" "This variant is a VUS because it does not have enough information."
488926 "chr21:35825662:C>T" "KCNE1" "NM_001270405:c.-50-3680G>A" "FIVE_PRIME_INTRON" "Benign" "rs4817651" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 371 1322 0.2806 83 1006 0.0825 210 694 0.3026 587 1008 0.5823 175 978 0.1789 1426 5008 0.284744
488927 "chr21:35825673:T>C" "KCNE1" "NM_001270405:c.-50-3691A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs41312377" "This variant is a VUS because it does not have enough information."
488928 "chr21:35825678:A>G" "KCNE1" "NM_001270405:c.-50-3696T>C" "FIVE_PRIME_INTRON" "Benign" "rs2027596" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1320 1322 0.9985 992 1006 0.9861 691 694 0.9957 1008 1008 1 978 978 1 4989 5008 0.996206
488929 "chr21:35825684:A>C" "KCNE1" "NM_001270405:c.-50-3702T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs76405167" "This variant is a VUS because it does not have enough information."
488930 "chr21:35825689:T>A" "KCNE1" "NM_001270405:c.-50-3707A>T" "FIVE_PRIME_INTRON" "Benign" "rs114635535" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 25 1322 0.0189 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 27 5008 0.00539137
488931 "chr21:35825733:T>C" "KCNE1" "NM_001270405:c.-50-3751A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs553858130" "This variant is a VUS because it does not have enough information."
488932 "chr21:35825763:C>T" "KCNE1" "NM_001270405:c.-50-3781G>A" "FIVE_PRIME_INTRON" "Benign" "rs529090462" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 0 1008 0 8 978 0.0082 8 5008 0.00159744
488933 "chr21:35825768:G>A" "KCNE1" "NM_001270405:c.-50-3786C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs41314731" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
488934 "chr21:35825816:T>C" "KCNE1" "NM_001270405:c.-50-3834A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs150508334" "This variant is a VUS because it does not have enough information."
488935 "chr21:35825830:C>T" "KCNE1" "NM_001270405:c.-50-3848G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs563679762" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488936 "chr21:35825834:T>C" "KCNE1" "NM_001270405:c.-50-3852A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs776594587" "This variant is a VUS because it does not have enough information."
488937 "chr21:35825921:T>A" "KCNE1" "NM_001270405:c.-50-3939A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs796645243" "This variant is a VUS because it does not have enough information."
488938 "chr21:35825931:A>C" "KCNE1" "NM_001270405:c.-50-3949T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs530987914" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488939 "chr21:35825935:T>C" "KCNE1" "NM_001270405:c.-50-3953A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs552303884" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488940 "chr21:35826050:T>C" "KCNE1" "NM_001270405:c.-50-4068A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs570795753" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
488941 "chr21:35826067:C>T" "KCNE1" "NM_001270405:c.-50-4085G>A" "FIVE_PRIME_INTRON" "Benign" "rs8133078" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 266 1322 0.2012 0 1006 0 12 694 0.0173 2 1008 0.002 7 978 0.0072 287 5008 0.0573083
488942 "chr21:35826068:G>A" "KCNE1" "NM_001270405:c.-50-4086C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs533821647" "This variant is a VUS because it does not have enough information."
488943 "chr21:35826085:T>C" "KCNE1" "NM_001270405:c.-50-4103A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs149687981" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488944 "chr21:35826111:G>A" "KCNE1" "NM_001270405:c.-50-4129C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs145519613" "This variant is a VUS because it does not have enough information." 0 1322 0 2 1006 0.002 1 694 0.0014 0 1008 0 2 978 0.002 5 5008 0.000998403
488945 "chr21:35826162:G>A" "KCNE1" "NM_001270405:c.-50-4180C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs142504964" "This variant is a VUS because it does not have enough information." 5 1322 0.0038 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 6 5008 0.00119808
488946 "chr21:35826193:C>T" "KCNE1" "NM_001270405:c.-50-4211G>A" "FIVE_PRIME_INTRON" "Benign" "rs144829604" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 30 1322 0.0227 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 32 5008 0.00638978
488947 "chr21:35826194:G>A" "KCNE1" "NM_001270405:c.-50-4212C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs371248742" "This variant is a VUS because it does not have enough information." 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403
488948 "chr21:35826207:A>-" "KCNE1" "NM_001270405:c.-50-4225delT" "FIVE_PRIME_INTRON" "Benign" "rs202246187" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 8 1322 0.0061 47 1006 0.0467 22 694 0.0317 60 1008 0.0595 103 978 0.1053 240 5008 0.0479233
488949 "chr21:35826238:T>A" "KCNE1" "NM_001270405:c.-50-4256A>T" "FIVE_PRIME_INTRON" "Benign" "rs73363383" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 341 1322 0.2579 1 1006 0.001 13 694 0.0187 2 1008 0.002 7 978 0.0072 364 5008 0.0726837
488950 "chr21:35826240:A>G" "KCNE1" "NM_001270405:c.-50-4258T>C" "FIVE_PRIME_INTRON" "Benign" "rs115819848" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 34 1322 0.0257 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 36 5008 0.0071885
488951 "chr21:35826253:T>C" "KCNE1" "NM_001270405:c.-50-4271A>G" "FIVE_PRIME_INTRON" "Benign" "rs76929781" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 342 1322 0.2587 1 1006 0.001 13 694 0.0187 2 1008 0.002 7 978 0.0072 365 5008 0.0728834
488952 "chr21:35826256:T>C" "KCNE1" "NM_001270405:c.-50-4274A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs750685640" "This variant is a VUS because it does not have enough information."
488953 "chr21:35826258:G>A" "KCNE1" "NM_001270405:c.-50-4276C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs539827419" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488954 "chr21:35826267:C>T" "KCNE1" "NM_001270405:c.-50-4285G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs756152645" "This variant is a VUS because it does not have enough information."
488955 "chr21:35826268:G>A" "KCNE1" "NM_001270405:c.-50-4286C>T" "FIVE_PRIME_INTRON" "Benign" "rs9982464" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 526 1322 0.3979 289 1006 0.2873 152 694 0.219 5 1008 0.005 258 978 0.2638 1230 5008 0.245607
488956 "chr21:35826299:C>T" "KCNE1" "NM_001270405:c.-50-4317G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs754319144" "This variant is a VUS because it does not have enough information."
488957 "chr21:35826323:C>A" "KCNE1" "NM_001270405:c.-50-4341G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs187060031" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488958 "chr21:35826338:G>-" "KCNE1" "NM_001270405:c.-50-4356delC" "FIVE_PRIME_INTRON" "Unknown significance" "rs773915890" "This variant is a VUS because it does not have enough information."
488959 "chr21:35826338:G>T" "KCNE1" "NM_001270405:c.-50-4356C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs544007758" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
488960 "chr21:35826340:T>C" "KCNE1" "NM_001270405:c.-50-4358A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs562663741" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
488961 "chr21:35826355:A>C" "KCNE1" "NM_001270405:c.-50-4373T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs11702197" "This variant is a VUS because it does not have enough information."
488962 "chr21:35826358:G>A" "KCNE1" "NM_001270405:c.-50-4376C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs147946631" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
488963 "chr21:35826360:G>A" "KCNE1" "NM_001270405:c.-50-4378C>T" "FIVE_PRIME_INTRON" "Benign" "rs1892593" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 346 1322 0.2617 319 1006 0.3171 327 694 0.4712 663 1008 0.6577 311 978 0.318 1966 5008 0.392572
488964 "chr21:35826362:G>T" "KCNE1" "NM_001270405:c.-50-4380C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs541932208" "This variant is a VUS because it does not have enough information."
488965 "chr21:35826389:A>C" "KCNE1" "NM_001270405:c.-50-4407T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs564405298" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 1 978 0.001 3 5008 0.000599042
488966 "chr21:35826389:A>T" "KCNE1" "NM_001270405:c.-50-4407T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs564405298" "This variant is a VUS because it does not have enough information."
488967 "chr21:35826414:C>T" "KCNE1" "NM_001270405:c.-50-4432G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs578096624" "This variant is a VUS because it does not have enough information."
488968 "chr21:35826451:A>G" "KCNE1" "NM_001270405:c.-50-4469T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs777342132" "This variant is a VUS because it does not have enough information."
488969 "chr21:35826518:T>C" "KCNE1" "NM_001270405:c.-51+4434A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs746676583" "This variant is a VUS because it does not have enough information."
488970 "chr21:35826535:G>T" "KCNE1" "NM_001270405:c.-51+4417C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs75106589" "This variant is a VUS because it does not have enough information." 0 1322 0 4 1006 0.004 1 694 0.0014 0 1008 0 1 978 0.001 6 5008 0.00119808
488971 "chr21:35826590:C>T" "KCNE1" "NM_001270405:c.-51+4362G>A" "FIVE_PRIME_INTRON" "Benign" "rs114519927" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 44 1322 0.0333 0 1006 0 3 694 0.0043 2 1008 0.002 7 978 0.0072 56 5008 0.0111821
488972 "chr21:35826598:C>T" "KCNE1" "NM_001270405:c.-51+4354G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs141850982" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
488973 "chr21:35826610:T>A" "KCNE1" "NM_001270405:c.-51+4342A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs529570692" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
488974 "chr21:35826660:A>G" "KCNE1" "NM_001270405:c.-51+4292T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs546421462" "This variant is a VUS because it does not have enough information."
488975 "chr21:35826668:A>G" "KCNE1" "NM_001270405:c.-51+4284T>C" "FIVE_PRIME_INTRON" "Benign" "rs73363384" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 149 1322 0.1127 1 1006 0.001 5 694 0.0072 2 1008 0.002 7 978 0.0072 164 5008 0.0327476
488976 "chr21:35826689:C>G" "KCNE1" "NM_001270405:c.-51+4263G>C" "FIVE_PRIME_INTRON" "Benign" "rs73363387" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 149 1322 0.1127 1 1006 0.001 5 694 0.0072 2 1008 0.002 7 978 0.0072 164 5008 0.0327476
488977 "chr21:35826691:C>A" "KCNE1" "NM_001270405:c.-51+4261G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs769688393" "This variant is a VUS because it does not have enough information."
488978 "chr21:35826724:C>T" "KCNE1" "NM_001270405:c.-51+4228G>A" "FIVE_PRIME_INTRON" "Benign" "rs73363388" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 149 1322 0.1127 1 1006 0.001 5 694 0.0072 2 1008 0.002 7 978 0.0072 164 5008 0.0327476
488979 "chr21:35826776:A>G" "KCNE1" "NM_001270405:c.-51+4176T>C" "FIVE_PRIME_INTRON" "Benign" "rs2070359" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1139 1322 0.8616 811 1006 0.8062 580 694 0.8357 821 1008 0.8145 817 978 0.8354 4168 5008 0.832268
488980 "chr21:35826797:A>G" "KCNE1" "NM_001270405:c.-51+4155T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs192224259" "This variant is a VUS because it does not have enough information." 4 1322 0.003 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 5 5008 0.000998403
488981 "chr21:35826799:G>T" "KCNE1" "NM_001270405:c.-51+4153C>A" "FIVE_PRIME_INTRON" "Benign" "rs78982432" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 150 1322 0.1135 1 1006 0.001 5 694 0.0072 2 1008 0.002 7 978 0.0072 165 5008 0.0329473
488982 "chr21:35826828:T>A" "KCNE1" "NM_001270405:c.-51+4124A>T" "FIVE_PRIME_INTRON" "Benign" "rs2070360" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 467 1322 0.3533 70 1006 0.0696 66 694 0.0951 156 1008 0.1548 110 978 0.1125 869 5008 0.173522
488983 "chr21:35826851:G>A" "KCNE1" "NM_001270405:c.-51+4101C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs547141276" "This variant is a VUS because it does not have enough information."
488984 "chr21:35826854:T>C" "KCNE1" "NM_001270405:c.-51+4098A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs760828139" "This variant is a VUS because it does not have enough information."
488985 "chr21:35826856:G>A" "KCNE1" "NM_001270405:c.-51+4096C>T" "FIVE_PRIME_INTRON" "Benign" "rs184382873" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 2 1322 0.0015 0 1006 0 0 694 0 2 1008 0.002 7 978 0.0072 11 5008 0.00219649
488986 "chr21:35826877:C>T" "KCNE1" "NM_001270405:c.-51+4075G>A" "FIVE_PRIME_INTRON" "Benign" "rs2070361" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 391 1322 0.2958 456 1006 0.4533 378 694 0.5447 664 1008 0.6587 461 978 0.4714 2350 5008 0.469249
488987 "chr21:35826879:C>A" "KCNE1" "NM_001270405:c.-51+4073G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs371719050" "This variant is a VUS because it does not have enough information."
488988 "chr21:35826885:A>G" "KCNE1" "NM_001270405:c.-51+4067T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs377598438" "This variant is a VUS because it does not have enough information."
488989 "chr21:35826910:G>A" "KCNE1" "NM_001270405:c.-51+4042C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs753901932" "This variant is a VUS because it does not have enough information."
488990 "chr21:35826922:A>G" "KCNE1" "NM_001270405:c.-51+4030T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs376826640" "This variant is a VUS because it does not have enough information."
488991 "chr21:35826923:A>T" "KCNE1" "NM_001270405:c.-51+4029T>A" "FIVE_PRIME_INTRON" "Benign" "rs2070362" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 18 1008 0.0179 43 978 0.044 61 5008 0.0121805
488992 "chr21:35826953:C>T" "KCNE1" "NM_001270405:c.-51+3999G>A" "FIVE_PRIME_INTRON" "Benign" "rs7277999" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1032 1322 0.7806 700 1006 0.6958 551 694 0.7939 1005 1008 0.997 725 978 0.7413 4013 5008 0.801318
488993 "chr21:35826955:G>A" "KCNE1" "NM_001270405:c.-51+3997C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs779337930" "This variant is a VUS because it does not have enough information."
488994 "chr21:35826989:T>A" "KCNE1" "NM_001270405:c.-51+3963A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs568623728" "This variant is a VUS because it does not have enough information."
488995 "chr21:35826999:A>C" "KCNE1" "NM_001270405:c.-51+3953T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs758726334" "This variant is a VUS because it does not have enough information."
488996 "chr21:35827026:G>C" "KCNE1" "NM_001270405:c.-51+3926C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs544863544" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
488997 "chr21:35827039:G>T" "KCNE1" "NM_001270405:c.-51+3913C>A" "FIVE_PRIME_INTRON" "Benign" "rs2070363" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 211 1322 0.1596 238 1006 0.2366 124 694 0.1787 96 1008 0.0952 181 978 0.1851 850 5008 0.169728
488998 "chr21:35827043:C>T" "KCNE1" "NM_001270405:c.-51+3909G>A" "FIVE_PRIME_INTRON" "Benign" "rs115706049" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 7 1322 0.0053 3 1006 0.003 1 694 0.0014 0 1008 0 0 978 0 11 5008 0.00219649
488999 "chr21:35827044:G>T" "KCNE1" "NM_001270405:c.-51+3908C>A" "FIVE_PRIME_INTRON" "Benign" "rs75231354" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 45 1322 0.034 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 47 5008 0.00938498
489000 "chr21:35827053:A>C" "KCNE1" "NM_001270405:c.-51+3899T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs562027269" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
489001 "chr21:35827059:C>G" "KCNE1" "NM_001270405:c.-51+3893G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs780752136" "This variant is a VUS because it does not have enough information."
489002 "chr21:35827063:A>G" "KCNE1" "NM_001270405:c.-51+3889T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs745428991" "This variant is a VUS because it does not have enough information."
489003 "chr21:35827067:C>T" "KCNE1" "NM_001270405:c.-51+3885G>A" "FIVE_PRIME_INTRON" "Benign" "rs58861465" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 9 1322 0.0068 69 1006 0.0686 48 694 0.0692 136 1008 0.1349 60 978 0.0613 322 5008 0.0642971
489004 "chr21:35827081:T>G" "KCNE1" "NM_001270405:c.-51+3871A>C" "FIVE_PRIME_INTRON" "Benign" "rs75125071" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 63 1322 0.0477 0 1006 0 4 694 0.0058 0 1008 0 0 978 0 67 5008 0.0133786
489005 "chr21:35827097:CAAA>-" "KCNE1" "NM_001270405:c.-51+3855_-51+3860delTTTG" "FIVE_PRIME_INTRON" "Unknown significance" "rs371680026" "This variant is a VUS because it does not have enough information."
489006 "chr21:35827103:G>C" "KCNE1" "NM_001270405:c.-51+3849C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs775499843" "This variant is a VUS because it does not have enough information."
489007 "chr21:35827120:A>G" "KCNE1" "NM_001270405:c.-51+3832T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs563026212" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489008 "chr21:35827150:G>A" "KCNE1" "NM_001270405:c.-51+3802C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs555656681" "This variant is a VUS because it does not have enough information."
489009 "chr21:35827155:T>G" "KCNE1" "NM_001270405:c.-51+3797A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs574709749" "This variant is a VUS because it does not have enough information."
489010 "chr21:35827183:A>G" "KCNE1" "NM_001270405:c.-51+3769T>C" "FIVE_PRIME_INTRON" "Benign" "rs7278200" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 518 1322 0.3918 703 1006 0.6988 538 694 0.7752 947 1008 0.9395 637 978 0.6513 3343 5008 0.667532
489011 "chr21:35827201:A>G" "KCNE1" "NM_001270405:c.-51+3751T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs79320078" "This variant is a VUS because it does not have enough information."
489012 "chr21:35827205:A>G" "KCNE1" "NM_001270405:c.-51+3747T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs79703908" "This variant is a VUS because it does not have enough information."
489013 "chr21:35827214:A>G" "KCNE1" "NM_001270405:c.-51+3738T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs76694287" "This variant is a VUS because it does not have enough information."
489014 "chr21:35827215:A>G" "KCNE1" "NM_001270405:c.-51+3737T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs79197703" "This variant is a VUS because it does not have enough information."
489015 "chr21:35827222:G>A" "KCNE1" "NM_001270405:c.-51+3730C>T" "FIVE_PRIME_INTRON" "Benign" "rs2070364" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 9 1322 0.0068 69 1006 0.0686 48 694 0.0692 136 1008 0.1349 60 978 0.0613 322 5008 0.0642971
489016 "chr21:35827229:C>A" "KCNE1" "NM_001270405:c.-51+3723G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs796984180" "This variant is a VUS because it does not have enough information."
489017 "chr21:35827244:C>T" "KCNE1" "NM_001270405:c.-51+3708G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs566235100" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489018 "chr21:35827288:T>G" "KCNE1" "NM_001270405:c.-51+3664A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs572567799" "This variant is a VUS because it does not have enough information."
489019 "chr21:35827308:A>T" "KCNE1" "NM_001270405:c.-51+3644T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs796130564" "This variant is a VUS because it does not have enough information."
489020 "chr21:35827322:T>A" "KCNE1" "NM_001270405:c.-51+3630A>T" "FIVE_PRIME_INTRON" "Benign" "rs41314817" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 29 1322 0.0219 0 1006 0 0 694 0 0 1008 0 0 978 0 29 5008 0.00579073
489021 "chr21:35827373:C>T" "KCNE1" "NM_001270405:c.-51+3579G>A" "FIVE_PRIME_INTRON" "Benign" "rs7278612" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1179 1322 0.8918 709 1006 0.7048 559 694 0.8055 1005 1008 0.997 728 978 0.7444 4180 5008 0.834665
489022 "chr21:35827415:A>C" "KCNE1" "NM_001270405:c.-51+3537T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs41314733" "This variant is a VUS because it does not have enough information."
489023 "chr21:35827429:A>G" "KCNE1" "NM_001270405:c.-51+3523T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs375469900" "This variant is a VUS because it does not have enough information."
489024 "chr21:35827431:A>G" "KCNE1" "NM_001270405:c.-51+3521T>C" "FIVE_PRIME_INTRON" "Benign" "rs7278630" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 892 1322 0.6747 707 1006 0.7028 553 694 0.7968 1005 1008 0.997 728 978 0.7444 3885 5008 0.775759
489025 "chr21:35827478:C>T" "KCNE1" "NM_001270405:c.-51+3474G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs375781876" "This variant is a VUS because it does not have enough information."
489026 "chr21:35827480:T>A" "KCNE1" "NM_001270405:c.-51+3472A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs369344200" "This variant is a VUS because it does not have enough information."
489027 "chr21:35827481:->A" "KCNE1" "NM_001270405:c.-51+3471_-51+3472insT" "FIVE_PRIME_INTRON" "Benign" "rs11427854" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 647 1322 0.4894 353 1006 0.3509 336 694 0.4841 572 1008 0.5675 448 978 0.4581 2356 5008 0.470447
489028 "chr21:35827535:A>T" "KCNE1" "NM_001270405:c.-51+3417T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs537424965" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489029 "chr21:35827547:T>C" "KCNE1" "NM_001270405:c.-51+3405A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs776756291" "This variant is a VUS because it does not have enough information."
489030 "chr21:35827550:A>G" "KCNE1" "NM_001270405:c.-51+3402T>C" "FIVE_PRIME_INTRON" "Benign" "rs140955734" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 4 1322 0.003 0 1006 0 0 694 0 2 1008 0.002 8 978 0.0082 14 5008 0.00279553
489031 "chr21:35827566:T>C" "KCNE1" "NM_001270405:c.-51+3386A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs577854022" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
489032 "chr21:35827577:G>A" "KCNE1" "NM_001270405:c.-51+3375C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs189480250" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489033 "chr21:35827585:C>T" "KCNE1" "NM_001270405:c.-51+3367G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs759471526" "This variant is a VUS because it does not have enough information."
489034 "chr21:35827593:T>C" "KCNE1" "NM_001270405:c.-51+3359A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs553644618" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489035 "chr21:35827645:A>G" "KCNE1" "NM_001270405:c.-51+3307T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs8133457" "This variant is a VUS because it does not have enough information."
489036 "chr21:35827664:C>A" "KCNE1" "NM_001270405:c.-51+3288G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs8133592" "This variant is a VUS because it does not have enough information."
489037 "chr21:35827757:T>C" "KCNE1" "NM_001270405:c.-51+3195A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs376996044" "This variant is a VUS because it does not have enough information."
489038 "chr21:35827766:C>T" "KCNE1" "NM_001270405:c.-51+3186G>A" "FIVE_PRIME_INTRON" "Benign" "rs182327510" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 3 1322 0.0023 0 1006 0 0 694 0 2 1008 0.002 8 978 0.0082 13 5008 0.00259585
489039 "chr21:35827824:C>T" "KCNE1" "NM_001270405:c.-51+3128G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs780774010" "This variant is a VUS because it does not have enough information."
489040 "chr21:35827836:GTGGCCTTGTCAGGCCCAGAAA>-" "KCNE1" "NM_001270405:c.-51+3116_-51+3139delTTTCTGGGCCTGACAAGGCCAC" "FIVE_PRIME_INTRON" "Benign" "rs536850956" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 0 1008 0 6 978 0.0061 6 5008 0.00119808
489041 "chr21:35827840:C>T" "KCNE1" "NM_001270405:c.-51+3112G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs765334155" "This variant is a VUS because it does not have enough information."
489042 "chr21:35827876:C>T" "KCNE1" "NM_001270405:c.-51+3076G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs753158687" "This variant is a VUS because it does not have enough information."
489043 "chr21:35827877:G>A" "KCNE1" "NM_001270405:c.-51+3075C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs749639300" "This variant is a VUS because it does not have enough information."
489044 "chr21:35827916:C>T" "KCNE1" "NM_001270405:c.-51+3036G>A" "FIVE_PRIME_INTRON" "Benign" "rs9977060" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 299 1322 0.2262 2 1006 0.002 12 694 0.0173 60 1008 0.0595 90 978 0.092 463 5008 0.0924521
489045 "chr21:35827917:C>T" "KCNE1" "NM_001270405:c.-51+3035G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs764412892" "This variant is a VUS because it does not have enough information."
489046 "chr21:35827936:->T" "KCNE1" "NM_001270405:c.-51+3016_-51+3017insA" "FIVE_PRIME_INTRON" "Unknown significance" "rs756238499" "This variant is a VUS because it does not have enough information."
489047 "chr21:35827941:T>G" "KCNE1" "NM_001270405:c.-51+3011A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs555877534" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489048 "chr21:35827944:T>C" "KCNE1" "NM_001270405:c.-51+3008A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs574117763" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489049 "chr21:35828010:G>T" "KCNE1" "NM_001270405:c.-51+2942C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs185659240" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489050 "chr21:35828025:G>A" "KCNE1" "NM_001270405:c.-51+2927C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs563242738" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 2 978 0.002 2 5008 0.000399361
489051 "chr21:35828036:A>G" "KCNE1" "NM_001270405:c.-51+2916T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs533415906" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489052 "chr21:35828075:G>A" "KCNE1" "NM_001270405:c.-51+2877C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs751935705" "This variant is a VUS because it does not have enough information."
489053 "chr21:35828120:C>T" "KCNE1" "NM_001270405:c.-51+2832G>A" "FIVE_PRIME_INTRON" "Benign" "rs545595654" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 24 1322 0.0182 1 1006 0.001 4 694 0.0058 0 1008 0 0 978 0 29 5008 0.00579073
489054 "chr21:35828121:G>A" "KCNE1" "NM_001270405:c.-51+2831C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs780651887" "This variant is a VUS because it does not have enough information."
489055 "chr21:35828126:G>A" "KCNE1" "NM_001270405:c.-51+2826C>T" "FIVE_PRIME_INTRON" "Benign" "rs138867573" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 18 1008 0.0179 29 978 0.0297 47 5008 0.00938498
489056 "chr21:35828143:C>A" "KCNE1" "NM_001270405:c.-51+2809G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs528839273" "This variant is a VUS because it does not have enough information."
489057 "chr21:35828172:C>T" "KCNE1" "NM_001270405:c.-51+2780G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs745537392" "This variant is a VUS because it does not have enough information."
489058 "chr21:35828173:G>A" "KCNE1" "NM_001270405:c.-51+2779C>T" "FIVE_PRIME_INTRON" "Benign" "rs12626657" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 86 1322 0.0651 2 1006 0.002 129 694 0.1859 473 1008 0.4692 23 978 0.0235 713 5008 0.142372
489059 "chr21:35828182:G>A" "KCNE1" "NM_001270405:c.-51+2770C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs747718833" "This variant is a VUS because it does not have enough information."
489060 "chr21:35828246:C>T" "KCNE1" "NM_001270405:c.-51+2706G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs779732964" "This variant is a VUS because it does not have enough information."
489061 "chr21:35828264:T>C" "KCNE1" "NM_001270405:c.-51+2688A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs548701973" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489062 "chr21:35828345:C>A" "KCNE1" "NM_001270405:c.-51+2607G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs576479921" "This variant is a VUS because it does not have enough information."
489063 "chr21:35828357:T>C" "KCNE1" "NM_001270405:c.-51+2595A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs749214615" "This variant is a VUS because it does not have enough information."
489064 "chr21:35828381:C>T" "KCNE1" "NM_001270405:c.-51+2571G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs771763034" "This variant is a VUS because it does not have enough information."
489065 "chr21:35828389:C>T" "KCNE1" "NM_001270405:c.-51+2563G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs768750166" "This variant is a VUS because it does not have enough information."
489066 "chr21:35828401:A>G" "KCNE1" "NM_001270405:c.-51+2551T>C" "FIVE_PRIME_INTRON" "Benign" "rs7283604" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 229 1322 0.1732 0 1006 0 9 694 0.013 0 1008 0 0 978 0 238 5008 0.047524
489067 "chr21:35828465:C>T" "KCNE1" "NM_001270405:c.-51+2487G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs531380748" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489068 "chr21:35828470:C>G" "KCNE1" "NM_001270405:c.-51+2482G>C" "FIVE_PRIME_INTRON" "Benign" "rs6517229" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 911 1322 0.6891 706 1006 0.7018 521 694 0.7507 912 1008 0.9048 675 978 0.6902 3725 5008 0.74381
489069 "chr21:35828476:T>-" "KCNE1" "NM_001270405:c.-51+2476delA" "FIVE_PRIME_INTRON" "Unknown significance" "rs758247340" "This variant is a VUS because it does not have enough information."
489070 "chr21:35828504:G>A" "KCNE1" "NM_001270405:c.-51+2448C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs56994212" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 2 1008 0.002 0 978 0 3 5008 0.000599042
489071 "chr21:35828620:T>C" "KCNE1" "NM_001270405:c.-51+2332A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs538521881" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489072 "chr21:35828660:G>C" "KCNE1" "NM_001270405:c.-51+2292C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs532493198" "This variant is a VUS because it does not have enough information."
489073 "chr21:35828679:G>A" "KCNE1" "NM_001270405:c.-51+2273C>T" "FIVE_PRIME_INTRON" "Benign" "rs73363394" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 61 1322 0.0461 1 1006 0.001 1 694 0.0014 0 1008 0 0 978 0 63 5008 0.0125799
489074 "chr21:35828686:C>T" "KCNE1" "NM_001270405:c.-51+2266G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs141701537" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489075 "chr21:35828718:C>T" "KCNE1" "NM_001270405:c.-51+2234G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs146240249" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489076 "chr21:35828778:G>C" "KCNE1" "NM_001270405:c.-51+2174C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs555938691" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
489077 "chr21:35828778:G>T" "KCNE1" "NM_001270405:c.-51+2174C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs555938691" "This variant is a VUS because it does not have enough information."
489078 "chr21:35828780:->T" "KCNE1" "NM_001270405:c.-51+2172_-51+2173insA" "FIVE_PRIME_INTRON" "Benign" "rs59835290" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 15 1322 0.0113 69 1006 0.0686 48 694 0.0692 136 1008 0.1349 61 978 0.0624 329 5008 0.0656949
489079 "chr21:35828792:G>A" "KCNE1" "NM_001270405:c.-51+2160C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs574047510" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489080 "chr21:35828794:T>C" "KCNE1" "NM_001270405:c.-51+2158A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs776679717" "This variant is a VUS because it does not have enough information."
489081 "chr21:35828808:T>C" "KCNE1" "NM_001270405:c.-51+2144A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs544601056" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489082 "chr21:35828810:T>A" "KCNE1" "NM_001270405:c.-51+2142A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs189322351" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489083 "chr21:35828821:G>A" "KCNE1" "NM_001270405:c.-51+2131C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs180814463" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 1 694 0.0014 0 1008 0 0 978 0 2 5008 0.000399361
489084 "chr21:35828828:C>T" "KCNE1" "NM_001270405:c.-51+2124G>A" "FIVE_PRIME_INTRON" "Benign" "rs73363395" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 23 1322 0.0174 0 1006 0 0 694 0 0 1008 0 0 978 0 23 5008 0.00459265
489085 "chr21:35828857:C>A" "KCNE1" "NM_001270405:c.-51+2095G>T" "FIVE_PRIME_INTRON" "Benign" "rs138075767" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 19 1008 0.0188 0 978 0 19 5008 0.00379393
489086 "chr21:35828873:C>T" "KCNE1" "NM_001270405:c.-51+2079G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs527919064" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
489087 "chr21:35828882:G>A" "KCNE1" "NM_001270405:c.-51+2070C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs149530336" "This variant is a VUS because it does not have enough information." 0 1322 0 3 1006 0.003 0 694 0 0 1008 0 2 978 0.002 5 5008 0.000998403
489088 "chr21:35828884:T>C" "KCNE1" "NM_001270405:c.-51+2068A>G" "FIVE_PRIME_INTRON" "Benign" "rs2226302" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 321 1322 0.2428 84 1006 0.0835 189 694 0.2723 568 1008 0.5635 131 978 0.1339 1293 5008 0.258187
489089 "chr21:35828923:A>T" "KCNE1" "NM_001270405:c.-51+2029T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs373179348" "This variant is a VUS because it does not have enough information."
489090 "chr21:35828929:T>C" "KCNE1" "NM_001270405:c.-51+2023A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs189938549" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361
489091 "chr21:35828952:T>C" "KCNE1" "NM_001270405:c.-51+2000A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs549764510" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489092 "chr21:35828968:C>T" "KCNE1" "NM_001270405:c.-51+1984G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs571128062" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 0 978 0 0 5008 0
489093 "chr21:35828993:C>A" "KCNE1" "NM_001270405:c.-51+1959G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs759348742" "This variant is a VUS because it does not have enough information."
489094 "chr21:35829022:T>C" "KCNE1" "NM_001270405:c.-51+1930A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs532109581" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489095 "chr21:35829031:T>C" "KCNE1" "NM_001270405:c.-51+1921A>G" "FIVE_PRIME_INTRON" "Benign" "rs144177455" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 18 1008 0.0179 29 978 0.0297 47 5008 0.00938498
489096 "chr21:35829070:C>A" "KCNE1" "NM_001270405:c.-51+1882G>T" "FIVE_PRIME_INTRON" "Benign" "rs915539" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1133 1322 0.857 708 1006 0.7038 561 694 0.8084 1005 1008 0.997 727 978 0.7434 4134 5008 0.825479
489097 "chr21:35829099:T>C" "KCNE1" "NM_001270405:c.-51+1853A>G" "FIVE_PRIME_INTRON" "Benign" "rs73363397" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 62 1322 0.0469 1 1006 0.001 1 694 0.0014 0 1008 0 0 978 0 64 5008 0.0127796
489098 "chr21:35829143:G>-" "KCNE1" "NM_001270405:c.-51+1809delC" "FIVE_PRIME_INTRON" "Unknown significance" "rs768372000" "This variant is a VUS because it does not have enough information."
489099 "chr21:35829146:T>C" "KCNE1" "NM_001270405:c.-51+1806A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs181557562" "This variant is a VUS because it does not have enough information."
489100 "chr21:35829147:C>T" "KCNE1" "NM_001270405:c.-51+1805G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs374709547" "This variant is a VUS because it does not have enough information."
489101 "chr21:35829170:C>T" "KCNE1" "NM_001270405:c.-51+1782G>A" "FIVE_PRIME_INTRON" "Benign" "rs73363398" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 61 1322 0.0461 1 1006 0.001 1 694 0.0014 0 1008 0 14 978 0.0143 77 5008 0.0153754
489102 "chr21:35829213:G>T" "KCNE1" "NM_001270405:c.-51+1739C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs199913000" "This variant is a VUS because it does not have enough information."
489103 "chr21:35829219:C>T" "KCNE1" "NM_001270405:c.-51+1733G>A" "FIVE_PRIME_INTRON" "Benign" "rs12482909" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 304 1322 0.23 553 1006 0.5497 305 694 0.4395 281 1008 0.2788 485 978 0.4959 1928 5008 0.384984
489104 "chr21:35829234:G>T" "KCNE1" "NM_001270405:c.-51+1718C>A" "FIVE_PRIME_INTRON" "Benign" "rs12482946" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 304 1322 0.23 553 1006 0.5497 305 694 0.4395 281 1008 0.2788 485 978 0.4959 1928 5008 0.384984
489105 "chr21:35829282:C>A" "KCNE1" "NM_001270405:c.-51+1670G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs767953918" "This variant is a VUS because it does not have enough information."
489106 "chr21:35829316:G>T" "KCNE1" "NM_001270405:c.-51+1636C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs556545725" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489107 "chr21:35829329:G>A" "KCNE1" "NM_001270405:c.-51+1623C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs186038171" "This variant is a VUS because it does not have enough information." 0 1322 0 2 1006 0.002 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
489108 "chr21:35829337:A>C" "KCNE1" "NM_001270405:c.-51+1615T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs755879400" "This variant is a VUS because it does not have enough information."
489109 "chr21:35829357:G>A" "KCNE1" "NM_001270405:c.-51+1595C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs779675811" "This variant is a VUS because it does not have enough information."
489110 "chr21:35829369:A>T" "KCNE1" "NM_001270405:c.-51+1583T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs558301433" "This variant is a VUS because it does not have enough information."
489111 "chr21:35829374:G>T" "KCNE1" "NM_001270405:c.-51+1578C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs538636072" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361
489112 "chr21:35829392:A>C" "KCNE1" "NM_001270405:c.-51+1560T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs554088233" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489113 "chr21:35829407:A>G" "KCNE1" "NM_001270405:c.-51+1545T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs754950792" "This variant is a VUS because it does not have enough information."
489114 "chr21:35829411:G>A" "KCNE1" "NM_001270405:c.-51+1541C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs572353393" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489115 "chr21:35829416:C>T" "KCNE1" "NM_001270405:c.-51+1536G>A" "FIVE_PRIME_INTRON" "Benign" "rs148602136" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 19 1006 0.0189 1 694 0.0014 0 1008 0 8 978 0.0082 28 5008 0.00559105
489116 "chr21:35829456:T>C" "KCNE1" "NM_001270405:c.-51+1496A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs561290180" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489117 "chr21:35829530:A>T" "KCNE1" "NM_001270405:c.-51+1422T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs190451479" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489118 "chr21:35829545:A>G" "KCNE1" "NM_001270405:c.-51+1407T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs373608743" "This variant is a VUS because it does not have enough information."
489119 "chr21:35829551:C>G" "KCNE1" "NM_001270405:c.-51+1401G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs543180224" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489120 "chr21:35829594:C>T" "KCNE1" "NM_001270405:c.-51+1358G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs537476711" "This variant is a VUS because it does not have enough information."
489121 "chr21:35829613:G>A" "KCNE1" "NM_001270405:c.-51+1339C>T" "FIVE_PRIME_INTRON" "Benign" "rs77766431" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 226 1322 0.171 0 1006 0 9 694 0.013 0 1008 0 0 978 0 235 5008 0.0469249
489122 "chr21:35829615:->TTTAT" "KCNE1" "NM_001270405:c.-51+1337_-51+1338insATAAA" "FIVE_PRIME_INTRON" "Unknown significance" "rs749419100" "This variant is a VUS because it does not have enough information."
489123 "chr21:35829646:C>G" "KCNE1" "NM_001270405:c.-51+1306G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs532052329" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489124 "chr21:35829647:G>A" "KCNE1" "NM_001270405:c.-51+1305C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs368565498" "This variant is a VUS because it does not have enough information."
489125 "chr21:35829675:G>A" "KCNE1" "NM_001270405:c.-51+1277C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs771717506" "This variant is a VUS because it does not have enough information."
489126 "chr21:35829676:C>A" "KCNE1" "NM_001270405:c.-51+1276G>T" "FIVE_PRIME_INTRON" "Benign" "rs60317712" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 321 1322 0.2428 84 1006 0.0835 190 694 0.2738 568 1008 0.5635 131 978 0.1339 1294 5008 0.258387
489127 "chr21:35829678:C>T" "KCNE1" "NM_001270405:c.-51+1274G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs559690395" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 3 978 0.0031 3 5008 0.000599042
489128 "chr21:35829696:A>C" "KCNE1" "NM_001270405:c.-51+1256T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs780685837" "This variant is a VUS because it does not have enough information."
489129 "chr21:35829704:C>T" "KCNE1" "NM_001270405:c.-51+1248G>A" "FIVE_PRIME_INTRON" "Benign" "rs117916248" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 3 1322 0.0023 96 1006 0.0954 45 694 0.0648 35 1008 0.0347 41 978 0.0419 220 5008 0.0439297
489130 "chr21:35829777:C>T" "KCNE1" "NM_001270405:c.-51+1175G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs548423935" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489131 "chr21:35829782:T>C" "KCNE1" "NM_001270405:c.-51+1170A>G" "FIVE_PRIME_INTRON" "Benign" "rs1892594" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1133 1322 0.857 709 1006 0.7048 561 694 0.8084 1005 1008 0.997 727 978 0.7434 4135 5008 0.825679
489132 "chr21:35829801:T>C" "KCNE1" "NM_001270405:c.-51+1151A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs368266908" "This variant is a VUS because it does not have enough information."
489133 "chr21:35829805:G>C" "KCNE1" "NM_001270405:c.-51+1147C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs537231059" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489134 "chr21:35829852:C>T" "KCNE1" "NM_001270405:c.-51+1100G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs775534964" "This variant is a VUS because it does not have enough information."
489135 "chr21:35829853:G>A" "KCNE1" "NM_001270405:c.-51+1099C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs550044673" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489136 "chr21:35829858:A>G" "KCNE1" "NM_001270405:c.-51+1094T>C" "FIVE_PRIME_INTRON" "Benign" "rs1892595" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1136 1322 0.8593 709 1006 0.7048 561 694 0.8084 1004 1008 0.996 728 978 0.7444 4138 5008 0.826278
489137 "chr21:35829864:C>T" "KCNE1" "NM_001270405:c.-51+1088G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs796349921" "This variant is a VUS because it does not have enough information."
489138 "chr21:35829885:G>T" "KCNE1" "NM_001270405:c.-51+1067C>A" "FIVE_PRIME_INTRON" "Benign" "rs1892596" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 303 1322 0.2292 553 1006 0.5497 305 694 0.4395 281 1008 0.2788 485 978 0.4959 1927 5008 0.384784
489139 "chr21:35829894:C>T" "KCNE1" "NM_001270405:c.-51+1058G>A" "FIVE_PRIME_INTRON" "Benign" "rs11088284" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 9 1322 0.0068 69 1006 0.0686 47 694 0.0677 154 1008 0.1528 89 978 0.091 368 5008 0.0734824
489140 "chr21:35829951:G>A" "KCNE1" "NM_001270405:c.-51+1001C>T" "FIVE_PRIME_INTRON" "Benign" "rs112781938" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 43 1322 0.0325 0 1006 0 3 694 0.0043 0 1008 0 0 978 0 46 5008 0.0091853
489141 "chr21:35829985:T>C" "KCNE1" "NM_001270405:c.-51+967A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs536519029" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361
489142 "chr21:35829987:G>A" "KCNE1" "NM_001270405:c.-51+965C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs555220089" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489143 "chr21:35829990:C>T" "KCNE1" "NM_001270405:c.-51+962G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs184037463" "This variant is a VUS because it does not have enough information."
489144 "chr21:35830027:C>T" "KCNE1" "NM_001270405:c.-51+925G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs576592920" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489145 "chr21:35830066:A>G" "KCNE1" "NM_001270405:c.-51+886T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs543987927" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489146 "chr21:35830185:C>T" "KCNE1" "NM_001270405:c.-51+767G>A" "FIVE_PRIME_INTRON" "Benign" "rs145176752" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 18 1008 0.0179 29 978 0.0297 47 5008 0.00938498
489147 "chr21:35830233:C>G" "KCNE1" "NM_001270405:c.-51+719G>C" "FIVE_PRIME_INTRON" "Benign" "rs75650525" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 9 1322 0.0068 69 1006 0.0686 47 694 0.0677 136 1008 0.1349 61 978 0.0624 322 5008 0.0642971
489148 "chr21:35830237:G>T" "KCNE1" "NM_001270405:c.-51+715C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs767749601" "This variant is a VUS because it does not have enough information."
489149 "chr21:35830252:C>G" "KCNE1" "NM_001270405:c.-51+700G>C" "FIVE_PRIME_INTRON" "Benign" "rs8127133" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 230 1322 0.174 0 1006 0 9 694 0.013 0 1008 0 0 978 0 239 5008 0.0477236
489150 "chr21:35830269:T>C" "KCNE1" "NM_001270405:c.-51+683A>G" "FIVE_PRIME_INTRON" "Benign" "rs147929811" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 2 1322 0.0015 29 1006 0.0288 8 694 0.0115 0 1008 0 2 978 0.002 41 5008 0.0081869
489151 "chr21:35830279:A>G" "KCNE1" "NM_001270405:c.-51+673T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs530041779" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489152 "chr21:35830320:A>T" "KCNE1" "NM_001270405:c.-51+632T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs548532604" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489153 "chr21:35830418:TTTG>-" "KCNE1" "NM_001270405:c.-51+534_-51+539delCAAA" "FIVE_PRIME_INTRON" "Benign" "rs201125878" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 233 1322 0.1762 1 1006 0.001 10 694 0.0144 20 1008 0.0198 50 978 0.0511 314 5008 0.0626997
489154 "chr21:35830436:->CTCTCT" "KCNE1" "NM_001270405:c.-51+516_-51+517insAGAGAG" "FIVE_PRIME_INTRON" "Benign" "rs145703054" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 29 1322 0.0219 0 1006 0 0 694 0 0 1008 0 0 978 0 29 5008 0.00579073
489155 "chr21:35830436:->CT" "KCNE1" "NM_001270405:c.-51+516_-51+517insAG" "FIVE_PRIME_INTRON" "Unknown significance" "rs145703054" "This variant is a VUS because it does not have enough information."
489156 "chr21:35830436:->CTCT" "KCNE1" "NM_001270405:c.-51+516_-51+517insAGAG" "FIVE_PRIME_INTRON" "Unknown significance" "rs145703054" "This variant is a VUS because it does not have enough information."
489157 "chr21:35830437:->CTCT" "KCNE1" "NM_001270405:c.-51+515_-51+516insAGAG" "FIVE_PRIME_INTRON" "Unknown significance" "rs72453130" "This variant is a VUS because it does not have enough information."
489158 "chr21:35830439:->CT" "KCNE1" "NM_001270405:c.-51+513_-51+514insAG" "FIVE_PRIME_INTRON" "Unknown significance" "rs145720300" "This variant is a VUS because it does not have enough information."
489159 "chr21:35830439:->TA" "KCNE1" "NM_001270405:c.-51+513_-51+514insTA" "FIVE_PRIME_INTRON" "Unknown significance" "rs145720300" "This variant is a VUS because it does not have enough information."
489160 "chr21:35830439:->TCTA" "KCNE1" "NM_001270405:c.-51+513_-51+514insTAGA" "FIVE_PRIME_INTRON" "Unknown significance" "rs145720300" "This variant is a VUS because it does not have enough information."
489161 "chr21:35830440:A>C" "KCNE1" "NM_001270405:c.-51+512T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs57773132" "This variant is a VUS because it does not have enough information."
489162 "chr21:35830441:->TCTC" "KCNE1" "NM_001270405:c.-51+511_-51+512insGAGA" "FIVE_PRIME_INTRON" "Unknown significance" "rs57328423" "This variant is a VUS because it does not have enough information."
489163 "chr21:35830442:A>C" "KCNE1" "NM_001270405:c.-51+510T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs4817652" "This variant is a VUS because it does not have enough information."
489164 "chr21:35830449:->TG" "KCNE1" "NM_001270405:c.-51+503_-51+504insCA" "FIVE_PRIME_INTRON" "Unknown significance" "rs201390134" "This variant is a VUS because it does not have enough information."
489165 "chr21:35830449:TG>-" "KCNE1" "NM_001270405:c.-51+503_-51+506delCA" "FIVE_PRIME_INTRON" "Unknown significance" "rs769915230" "This variant is a VUS because it does not have enough information."
489166 "chr21:35830450:G>A" "KCNE1" "NM_001270405:c.-51+502C>T" "FIVE_PRIME_INTRON" "Benign" "rs1475907" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 289 1322 0.2186 495 1006 0.492 273 694 0.3934 269 1008 0.2669 460 978 0.4703 1786 5008 0.356629
489167 "chr21:35830463:C>T" "KCNE1" "NM_001270405:c.-51+489G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs112021756" "This variant is a VUS because it does not have enough information."
489168 "chr21:35830464:G>A" "KCNE1" "NM_001270405:c.-51+488C>T" "FIVE_PRIME_INTRON" "Benign" "rs140566169" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 5 1322 0.0038 0 1006 0 97 694 0.1398 6 1008 0.006 0 978 0 108 5008 0.0215655
489169 "chr21:35830465:C>T" "KCNE1" "NM_001270405:c.-51+487G>A" "FIVE_PRIME_INTRON" "Benign" "rs552301311" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 2 1322 0.0015 12 1006 0.0119 5 694 0.0072 3 1008 0.003 8 978 0.0082 30 5008 0.00599042
489170 "chr21:35830466:GT>-" "KCNE1" "NM_001270405:c.-51+486_-51+489delAC" "FIVE_PRIME_INTRON" "Unknown significance" "rs10603735" "This variant is a VUS because it does not have enough information."
489171 "chr21:35830466:G>A" "KCNE1" "NM_001270405:c.-51+486C>T" "FIVE_PRIME_INTRON" "Benign" "rs571656329" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 9 978 0.0092 10 5008 0.00199681
489172 "chr21:35830486:C>T" "KCNE1" "NM_001270405:c.-51+466G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs532435310" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489173 "chr21:35830571:C>A" "KCNE1" "NM_001270405:c.-51+381G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs547409591" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489174 "chr21:35830602:G>C" "KCNE1" "NM_001270405:c.-51+350C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs776140206" "This variant is a VUS because it does not have enough information."
489175 "chr21:35830624:T>C" "KCNE1" "NM_001270405:c.-51+328A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs373289233" "This variant is a VUS because it does not have enough information."
489176 "chr21:35830633:G>A" "KCNE1" "NM_001270405:c.-51+319C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs565764138" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489177 "chr21:35830666:G>A" "KCNE1" "NM_001270405:c.-51+286C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs372012575" "This variant is a VUS because it does not have enough information."
489178 "chr21:35830680:G>C" "KCNE1" "NM_001270405:c.-51+272C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs753551267" "This variant is a VUS because it does not have enough information."
489179 "chr21:35830742:G>C" "KCNE1" "NM_001270405:c.-51+210C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs536229125" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
489180 "chr21:35830757:C>T" "KCNE1" "NM_001270405:c.-51+195G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs199616680" "This variant is a VUS because it does not have enough information."
489181 "chr21:35830770:G>T" "KCNE1" "NM_001270405:c.-51+182C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs555004409" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489182 "chr21:35830781:->GC" "KCNE1" "NM_001270405:c.-51+171_-51+172insGC" "FIVE_PRIME_INTRON" "Unknown significance" "rs199596905" "This variant is a VUS because it does not have enough information."
489183 "chr21:35830782:G>A" "KCNE1" "NM_001270405:c.-51+170C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs570327078" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489184 "chr21:35830783:C>T" "KCNE1" "NM_001270405:c.-51+169G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs537251846" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489185 "chr21:35830791:A>G" "KCNE1" "NM_001270405:c.-51+161T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs559067847" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489186 "chr21:35830858:A>G" "KCNE1" "NM_001270405:c.-51+94T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs188966068" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
489187 "chr21:35830881:T>C" "KCNE1" "NM_001270405:c.-51+71A>G" "FIVE_PRIME_INTRON" "Benign" "rs41312379" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 230 1322 0.174 0 1006 0 9 694 0.013 0 1008 0 0 978 0 239 5008 0.0477236
489188 "chr21:35830898:G>A" "KCNE1" "NM_001270405:c.-51+54C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs56092601" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489189 "chr21:35830919:A>G" "KCNE1" "NM_001270405:c.-51+33T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs778510713" "This variant is a VUS because it does not have enough information."
489190 "chr21:35830931:C>T" "KCNE1" "NM_001270405:c.-51+21G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs41314735" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 3 1008 0.003 0 978 0 3 5008 0.000599042
489191 "chr21:35830941:G>C" "KCNE1" "NM_001270405:c.-51+11C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs752558922" "This variant is a VUS because it does not have enough information."
489192 "chr21:35830957:T>C" "KCNE1" "NM_001270405:c.-56A>G" "FIVE_PRIME_EXON" "Unknown significance" "rs758405737" "This variant is a VUS because it does not have enough information."
489193 "chr21:35830983:A>C" "KCNE1" "NM_001270405:c.-82T>G" "FIVE_PRIME_EXON" "Unknown significance" "rs145416040" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489194 "chr21:35831001:A>G" "KCNE1" "NM_001270405:c.-100T>C" "FIVE_PRIME_EXON" "Benign" "rs41314819" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 23 1322 0.0174 0 1006 0 0 694 0 0 1008 0 0 978 0 23 5008 0.00459265
489195 "chr21:35831002:T>A" "KCNE1" "NM_001270405:c.-101A>T" "FIVE_PRIME_EXON" "Unknown significance" "rs74706643" "This variant is a VUS because it does not have enough information." 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403
489196 "chr21:35831034:A>T" "KCNE1" "NM_001270403:c.-133T>A" "FIVE_PRIME_EXON" "Unknown significance" "rs143242537" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489197 "chr21:35831035:C>A" "KCNE1" "NM_001270403:c.-133-1G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs563910117" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489198 "chr21:35831096:T>A" "KCNE1" "NM_001270405:c.-161-34A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs777426726" "This variant is a VUS because it does not have enough information."
489199 "chr21:35831097:A>T" "KCNE1" "NM_001270405:c.-161-35T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs528249742" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489200 "chr21:35831132:C>T" "KCNE1" "NM_001270405:c.-161-70G>A" "FIVE_PRIME_INTRON" "Benign" "rs182667173" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 8 1008 0.0079 0 978 0 8 5008 0.00159744
489201 "chr21:35831153:T>C" "KCNE1" "NM_001270405:c.-161-91A>G" "FIVE_PRIME_INTRON" "Benign" "rs187207470" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 15 1322 0.0113 0 1006 0 0 694 0 0 1008 0 0 978 0 15 5008 0.00299521
489202 "chr21:35831198:T>G" "KCNE1" "NM_001270405:c.-161-136A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs530083369" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489203 "chr21:35831238:A>T" "KCNE1" "NM_001270405:c.-161-176T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs548519452" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
489204 "chr21:35831266:A>G" "KCNE1" "NM_001270405:c.-161-204T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs41312381" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
489205 "chr21:35831278:T>C" "KCNE1" "NM_001270405:c.-161-216A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs537716912" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489206 "chr21:35831306:T>G" "KCNE1" "NM_001270405:c.-161-244A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs746866167" "This variant is a VUS because it does not have enough information."
489207 "chr21:35831406:G>C" "KCNE1" "NM_001270405:c.-161-344C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs558909485" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 2 978 0.002 2 5008 0.000399361
489208 "chr21:35831412:C>A" "KCNE1" "NM_001270405:c.-161-350G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs566048548" "This variant is a VUS because it does not have enough information."
489209 "chr21:35831416:G>C" "KCNE1" "NM_001270405:c.-161-354C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs539854616" "This variant is a VUS because it does not have enough information."
489210 "chr21:35831430:T>C" "KCNE1" "NM_001270405:c.-161-368A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs780185676" "This variant is a VUS because it does not have enough information."
489211 "chr21:35831435:C>A" "KCNE1" "NM_001270405:c.-161-373G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs749540720" "This variant is a VUS because it does not have enough information."
489212 "chr21:35831484:G>A" "KCNE1" "NM_001270405:c.-161-422C>T" "FIVE_PRIME_INTRON" "Benign" "rs146799021" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 11 1006 0.0109 7 694 0.0101 0 1008 0 1 978 0.001 19 5008 0.00379393
489213 "chr21:35831502:T>C" "KCNE1" "NM_001270405:c.-161-440A>G" "FIVE_PRIME_INTRON" "Benign" "rs75970341" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 230 1322 0.174 0 1006 0 9 694 0.013 0 1008 0 0 978 0 239 5008 0.0477236
489214 "chr21:35831539:A>G" "KCNE1" "NM_001270405:c.-161-477T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs762195736" "This variant is a VUS because it does not have enough information."
489215 "chr21:35831559:T>A" "KCNE1" "NM_001270405:c.-161-497A>T" "FIVE_PRIME_INTRON" "Benign" "rs79351273" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 230 1322 0.174 0 1006 0 9 694 0.013 0 1008 0 0 978 0 239 5008 0.0477236
489216 "chr21:35831566:G>A" "KCNE1" "NM_001270405:c.-161-504C>T" "FIVE_PRIME_INTRON" "Benign" "rs140608406" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1 1322 0.0008 5 1006 0.005 1 694 0.0014 0 1008 0 0 978 0 7 5008 0.00139776
489217 "chr21:35831621:T>C" "KCNE1" "NM_001270405:c.-161-559A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs541468749" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489218 "chr21:35831628:A>T" "KCNE1" "NM_001270405:c.-161-566T>A" "FIVE_PRIME_INTRON" "Benign" "rs7275915" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 81 1322 0.0613 178 1006 0.1769 111 694 0.1599 148 1008 0.1468 114 978 0.1166 632 5008 0.126198
489219 "chr21:35831678:G>A" "KCNE1" "NM_001270405:c.-162+519C>T" "FIVE_PRIME_INTRON" "Benign" "rs138006048" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 15 1008 0.0149 0 978 0 15 5008 0.00299521
489220 "chr21:35831693:G>A" "KCNE1" "NM_001270405:c.-162+504C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs574183515" "This variant is a VUS because it does not have enough information."
489221 "chr21:35831703:C>T" "KCNE1" "NM_001270405:c.-162+494G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs118083993" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489222 "chr21:35831711:C>T" "KCNE1" "NM_001270405:c.-162+486G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs564022767" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361
489223 "chr21:35831719:C>T" "KCNE1" "NM_001270405:c.-162+478G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs141741967" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489224 "chr21:35831734:C>G" "KCNE1" "NM_001270405:c.-162+463G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs753494277" "This variant is a VUS because it does not have enough information."
489225 "chr21:35831735:G>A" "KCNE1" "NM_001270405:c.-162+462C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs540035736" "This variant is a VUS because it does not have enough information." 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042
489226 "chr21:35831741:G>T" "KCNE1" "NM_001270405:c.-162+456C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs559636443" "This variant is a VUS because it does not have enough information."
489227 "chr21:35831753:A>T" "KCNE1" "NM_001270405:c.-162+444T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs559425033" "This variant is a VUS because it does not have enough information." 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403
489228 "chr21:35831773:C>G" "KCNE1" "NM_001270405:c.-162+424G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs773618593" "This variant is a VUS because it does not have enough information."
489229 "chr21:35831815:A>C" "KCNE1" "NM_001270405:c.-162+382T>G" "FIVE_PRIME_INTRON" "Benign" "rs8127493" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1321 1322 0.9992 989 1006 0.9831 691 694 0.9957 1008 1008 1 968 978 0.9898 4977 5008 0.99381
489230 "chr21:35831815:A>T" "KCNE1" "NM_001270405:c.-162+382T>A" "FIVE_PRIME_INTRON" "Benign" "rs8127493" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 7 1006 0.007 1 694 0.0014 0 1008 0 10 978 0.0102 18 5008 0.00359425
489231 "chr21:35831834:T>G" "KCNE1" "NM_001127669:c.-141A>C" "FIVE_PRIME_EXON" "Unknown significance" "rs563675140" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489232 "chr21:35831837:G>C" "KCNE1" "NM_001127669:c.-144C>G" "FIVE_PRIME_EXON" "Unknown significance" "rs530792686" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361
489233 "chr21:35831842:C>A" "KCNE1" "NM_001270405:c.-162+355G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs552869384" "This variant is a VUS because it does not have enough information." 3 1322 0.0023 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 4 5008 0.000798722
489234 "chr21:35831867:T>C" "KCNE1" "NM_001270405:c.-162+330A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs761000872" "This variant is a VUS because it does not have enough information."
489235 "chr21:35831935:C>T" "KCNE1" "NM_001270405:c.-162+262G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs571152383" "This variant is a VUS because it does not have enough information." 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403
489236 "chr21:35831937:C>A" "KCNE1" "NM_001270405:c.-162+260G>T" "FIVE_PRIME_INTRON" "Benign" "rs114742950" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 230 1322 0.174 0 1006 0 9 694 0.013 0 1008 0 0 978 0 239 5008 0.0477236
489237 "chr21:35831943:A>G" "KCNE1" "NM_001270405:c.-162+254T>C" "FIVE_PRIME_INTRON" "Benign" "rs191629273" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 231 1322 0.1747 0 1006 0 9 694 0.013 0 1008 0 0 978 0 240 5008 0.0479233
489238 "chr21:35831954:C>T" "KCNE1" "NM_001270405:c.-162+243G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs766531049" "This variant is a VUS because it does not have enough information."
489239 "chr21:35831988:C>T" "KCNE1" "NM_001270405:c.-162+209G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs763962849" "This variant is a VUS because it does not have enough information."
489240 "chr21:35832019:A>T" "KCNE1" "NM_001270405:c.-162+178T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs377209555" "This variant is a VUS because it does not have enough information."
489241 "chr21:35832025:C>T" "KCNE1" "NM_001270405:c.-162+172G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs568174200" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 3 1008 0.003 0 978 0 3 5008 0.000599042
489242 "chr21:35832048:C>T" "KCNE1" "NM_001270405:c.-162+149G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs535502966" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489243 "chr21:35832052:G>C" "KCNE1" "NM_001270405:c.-162+145C>G" "FIVE_PRIME_INTRON" "Benign" "rs372530461" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 10 1322 0.0076 0 1006 0 0 694 0 0 1008 0 0 978 0 10 5008 0.00199681
489244 "chr21:35832053:->C" "KCNE1" "NM_001270405:c.-162+144_-162+145insG" "FIVE_PRIME_INTRON" "Benign" "rs143258813" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 13 1322 0.0098 84 1006 0.0835 52 694 0.0749 94 1008 0.0933 108 978 0.1104 351 5008 0.0700879
489245 "chr21:35832053:->CC" "KCNE1" "NM_001270405:c.-162+144_-162+145insGG" "FIVE_PRIME_INTRON" "Unknown significance" "rs143258813" "This variant is a VUS because it does not have enough information."
489246 "chr21:35832053:C>-" "KCNE1" "NM_001270405:c.-162+144delG" "FIVE_PRIME_INTRON" "Unknown significance" "rs74162058" "This variant is a VUS because it does not have enough information."
489247 "chr21:35832057:C>A" "KCNE1" "NM_001270405:c.-162+140G>T" "FIVE_PRIME_INTRON" "Benign" "rs112951465" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 0 1008 0 5 978 0.0051 5 5008 0.000998403
489248 "chr21:35832057:C>G" "KCNE1" "NM_001270405:c.-162+140G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs112951465" "This variant is a VUS because it does not have enough information."
489249 "chr21:35832090:C>A" "KCNE1" "NM_001270405:c.-162+107G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs757007783" "This variant is a VUS because it does not have enough information."
489250 "chr21:35832090:C>G" "KCNE1" "NM_001270405:c.-162+107G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs757007783" "This variant is a VUS because it does not have enough information."
489251 "chr21:35832102:T>C" "KCNE1" "NM_001270405:c.-162+95A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs753961071" "This variant is a VUS because it does not have enough information."
489252 "chr21:35832140:C>T" "KCNE1" "NM_001270405:c.-162+57G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs749489172" "This variant is a VUS because it does not have enough information."
489253 "chr21:35832162:->A" "KCNE1" "NM_001270405:c.-162+35_-162+36insT" "FIVE_PRIME_INTRON" "Unknown significance" "rs376977071" "This variant is a VUS because it does not have enough information."
489254 "chr21:35832174:G>T" "KCNE1" "NM_001270405:c.-162+23C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs184158255" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
489255 "chr21:35832211:T>C" "KCNE1" "NM_001270405:c.-176A>G" "FIVE_PRIME_EXON" "Unknown significance" "rs544610220" "This variant is a VUS because it does not have enough information."
489256 "chr21:35832222:A>-" "KCNE1" "NM_001270405:c.-187delT" "FIVE_PRIME_EXON" "Unknown significance" "rs565877083" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 3 978 0.0031 4 5008 0.000798722
489257 "chr21:35832223:G>C" "KCNE1" "NM_001270405:c.-188C>G" "FIVE_PRIME_EXON" "Unknown significance" "rs557675906" "This variant is a VUS because it does not have enough information." 4 1322 0.003 0 1006 0 0 694 0 0 1008 0 0 978 0 4 5008 0.000798722
489258 "chr21:35832227:G>A" "KCNE1" "NM_001270405:c.-192C>T" "FIVE_PRIME_EXON" "Unknown significance" "rs373092325" "This variant is a VUS because it does not have enough information."
489259 "chr21:35832245:G>A" "KCNE1" "NM_001270405:c.-210C>T" "FIVE_PRIME_FLANK" "Unknown significance" "rs371206730" "This variant is a VUS because it does not have enough information."
489260 "chr21:35832254:C>A" "KCNE1" "NM_001270404:c.-50-10272G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs755268019" "This variant is a VUS because it does not have enough information."
489261 "chr21:35832267:->C" "KCNE1" "NM_001270404:c.-50-10285_-50-10284insG" "FIVE_PRIME_INTRON" "Unknown significance" "rs35131534" "This variant is a VUS because it does not have enough information."
489262 "chr21:35832276:C>T" "KCNE1" "NM_001270404:c.-50-10294G>A" "FIVE_PRIME_INTRON" "Benign" "rs78921201" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 9 1322 0.0068 69 1006 0.0686 47 694 0.0677 136 1008 0.1349 61 978 0.0624 322 5008 0.0642971
489263 "chr21:35832280:C>T" "KCNE1" "NM_001270404:c.-50-10298G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs530619148" "This variant is a VUS because it does not have enough information."
489264 "chr21:35832285:G>A" "KCNE1" "NM_001270404:c.-50-10303C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs796875096" "This variant is a VUS because it does not have enough information."
489265 "chr21:35832311:T>-" "KCNE1" "NM_001270404:c.-50-10329delA" "FIVE_PRIME_INTRON" "Unknown significance" "rs758428175" "This variant is a VUS because it does not have enough information."
489266 "chr21:35832317:A>G" "KCNE1" "NM_001270404:c.-50-10335T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs187657886" "This variant is a VUS because it does not have enough information."
489267 "chr21:35832334:C>T" "KCNE1" "NM_001270404:c.-50-10352G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs540049208" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489268 "chr21:35832335:G>A" "KCNE1" "NM_001270404:c.-50-10353C>T" "FIVE_PRIME_INTRON" "Benign" "rs11702790" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 77 1322 0.0582 376 1006 0.3738 188 694 0.2709 95 1008 0.0942 332 978 0.3395 1068 5008 0.213259
489269 "chr21:35832337:T>C" "KCNE1" "NM_001270404:c.-50-10355A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs574859371" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489270 "chr21:35832340:C>T" "KCNE1" "NM_001270404:c.-50-10358G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs193083566" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 2 1008 0.002 1 978 0.001 5 5008 0.000998403
489271 "chr21:35832343:C>T" "KCNE1" "NM_001270404:c.-50-10361G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs138644260" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489272 "chr21:35832360:G>T" "KCNE1" "NM_001270404:c.-50-10378C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs772054614" "This variant is a VUS because it does not have enough information."
489273 "chr21:35832365:G>T" "KCNE1" "NM_001270404:c.-50-10383C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs773786157" "This variant is a VUS because it does not have enough information."
489274 "chr21:35832368:CC>-" "KCNE1" "NM_001270404:c.-50-10386_-50-10383delGG" "FIVE_PRIME_INTRON" "Benign" "rs147302594" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 230 1322 0.174 0 1006 0 9 694 0.013 0 1008 0 0 978 0 239 5008 0.0477236
489275 "chr21:35832373:G>C" "KCNE1" "NM_001270404:c.-50-10391C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs77864079" "This variant is a VUS because it does not have enough information."
489276 "chr21:35832398:A>G" "KCNE1" "NM_001270404:c.-50-10416T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs747547974" "This variant is a VUS because it does not have enough information."
489277 "chr21:35832406:T>C" "KCNE1" "NM_001270404:c.-50-10424A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs771403478" "This variant is a VUS because it does not have enough information."
489278 "chr21:35832414:C>T" "KCNE1" "NM_001270404:c.-50-10432G>A" "FIVE_PRIME_INTRON" "Benign" "rs73363401" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 61 1322 0.0461 1 1006 0.001 1 694 0.0014 0 1008 0 0 978 0 63 5008 0.0125799
489279 "chr21:35832473:G>A" "KCNE1" "NM_001270404:c.-50-10491C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs549409797" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361
489280 "chr21:35832476:C>T" "KCNE1" "NM_001270404:c.-50-10494G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs759111284" "This variant is a VUS because it does not have enough information."
489281 "chr21:35832477:G>A" "KCNE1" "NM_001270404:c.-50-10495C>T" "FIVE_PRIME_INTRON" "Benign" "rs116871414" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 1 1006 0.001 3 694 0.0043 9 1008 0.0089 0 978 0 13 5008 0.00259585
489282 "chr21:35832506:G>A" "KCNE1" "NM_001270404:c.-50-10524C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs115274861" "This variant is a VUS because it does not have enough information."
489283 "chr21:35832522:A>T" "KCNE1" "NM_001270404:c.-50-10540T>A" "FIVE_PRIME_INTRON" "Benign" "rs79622898" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 46 1008 0.0456 1 978 0.001 47 5008 0.00938498
489284 "chr21:35832524:C>T" "KCNE1" "NM_001270404:c.-50-10542G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs547234681" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
489285 "chr21:35832535:T>G" "KCNE1" "NM_001270404:c.-50-10553A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs41314821" "This variant is a VUS because it does not have enough information."
489286 "chr21:35832545:C>T" "KCNE1" "NM_001270404:c.-50-10563G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs528293376" "This variant is a VUS because it does not have enough information."
489287 "chr21:35832551:G>A" "KCNE1" "NM_001270404:c.-50-10569C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs41314737" "This variant is a VUS because it does not have enough information."
489288 "chr21:35832555:C>A" "KCNE1" "NM_001270404:c.-50-10573G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs762460434" "This variant is a VUS because it does not have enough information."
489289 "chr21:35832586:A>T" "KCNE1" "NM_001270404:c.-50-10604T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs568663861" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489290 "chr21:35832613:T>C" "KCNE1" "NM_001270404:c.-50-10631A>G" "FIVE_PRIME_INTRON" "Benign" "rs41314823" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 76 1322 0.0575 0 1006 0 3 694 0.0043 0 1008 0 0 978 0 79 5008 0.0157748
489291 "chr21:35832637:G>A" "KCNE1" "NM_001270404:c.-50-10655C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs370952819" "This variant is a VUS because it does not have enough information."
489292 "chr21:35832640:->AGG" "KCNE1" "NM_001270404:c.-50-10658_-50-10657insCCT" "FIVE_PRIME_INTRON" "Unknown significance" "rs72550280" "This variant is a VUS because it does not have enough information."
489293 "chr21:35832641:GAG>-" "KCNE1" "NM_001270404:c.-50-10659_-50-10655delCTC" "FIVE_PRIME_INTRON" "Benign" "rs537324826" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 7 1322 0.0053 0 1006 0 0 694 0 0 1008 0 0 978 0 7 5008 0.00139776
489294 "chr21:35832668:AATCCCATG>-" "KCNE1" "NM_001270404:c.-50-10686_-50-10676delCATGGGATT" "FIVE_PRIME_INTRON" "Unknown significance" "rs140952378" "This variant is a VUS because it does not have enough information."
489295 "chr21:35832685:A>G" "KCNE1" "NM_001270404:c.-50-10703T>C" "FIVE_PRIME_INTRON" "Benign" "rs41312383" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 230 1322 0.174 0 1006 0 9 694 0.013 0 1008 0 0 978 0 239 5008 0.0477236
489296 "chr21:35832694:C>T" "KCNE1" "NM_001270404:c.-50-10712G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs77410801" "This variant is a VUS because it does not have enough information."
489297 "chr21:35832725:G>A" "KCNE1" "NM_001270404:c.-50-10743C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs41314739" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489298 "chr21:35832729:C>T" "KCNE1" "NM_001270404:c.-50-10747G>A" "FIVE_PRIME_INTRON" "Benign" "rs41314741" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 230 1322 0.174 1 1006 0.001 9 694 0.013 23 1008 0.0228 0 978 0 263 5008 0.052516
489299 "chr21:35832740:G>A" "KCNE1" "NM_001270404:c.-50-10758C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs57404486" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489300 "chr21:35832782:C>T" "KCNE1" "NM_001270404:c.-50-10800G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs572818254" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489301 "chr21:35832811:T>A" "KCNE1" "NM_001270404:c.-50-10829A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs371099136" "This variant is a VUS because it does not have enough information."
489302 "chr21:35832822:C>T" "KCNE1" "NM_001270404:c.-50-10840G>A" "FIVE_PRIME_INTRON" "Benign" "rs58650140" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 23 1322 0.0174 0 1006 0 0 694 0 0 1008 0 0 978 0 23 5008 0.00459265
489303 "chr21:35832825:C>T" "KCNE1" "NM_001270404:c.-50-10843G>A" "FIVE_PRIME_INTRON" "Benign" "rs190530197" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 3 1322 0.0023 0 1006 0 0 694 0 2 1008 0.002 7 978 0.0072 12 5008 0.00239617
489304 "chr21:35832839:T>C" "KCNE1" "NM_001270404:c.-50-10857A>G" "FIVE_PRIME_INTRON" "Benign" "rs115187314" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 53 1322 0.0401 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 55 5008 0.0109824
489305 "chr21:35832854:T>C" "KCNE1" "NM_001270404:c.-50-10872A>G" "FIVE_PRIME_INTRON" "Benign" "rs114124180" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 28 1322 0.0212 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 29 5008 0.00579073
489306 "chr21:35832872:G>A" "KCNE1" "NM_001270404:c.-50-10890C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs563855162" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489307 "chr21:35832878:C>T" "KCNE1" "NM_001270404:c.-50-10896G>A" "FIVE_PRIME_INTRON" "Benign" "rs59125652" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 253 1322 0.1914 0 1006 0 9 694 0.013 0 1008 0 0 978 0 262 5008 0.0523163
489308 "chr21:35832879:G>A" "KCNE1" "NM_001270404:c.-50-10897C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs368061648" "This variant is a VUS because it does not have enough information."
489309 "chr21:35832940:C>T" "KCNE1" "NM_001270404:c.-50-10958G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs756933962" "This variant is a VUS because it does not have enough information."
489310 "chr21:35832982:G>C" "KCNE1" "NM_001270404:c.-50-11000C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs546231569" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489311 "chr21:35833017:->T" "KCNE1" "NM_001270404:c.-50-11035_-50-11034insA" "FIVE_PRIME_INTRON" "Unknown significance" "rs58486177" "This variant is a VUS because it does not have enough information."
489312 "chr21:35833017:T>-" "KCNE1" "NM_001270404:c.-50-11035delA" "FIVE_PRIME_INTRON" "Unknown significance" "rs370620614" "This variant is a VUS because it does not have enough information."
489313 "chr21:35833021:T>C" "KCNE1" "NM_001270404:c.-50-11039A>G" "FIVE_PRIME_INTRON" "Benign" "rs115793831" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 32 1322 0.0242 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 34 5008 0.00678914
489314 "chr21:35833024:T>C" "KCNE1" "NM_001270404:c.-50-11042A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs528470996" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
489315 "chr21:35833039:->A" "KCNE1" "NM_001270404:c.-50-11057_-50-11056insT" "FIVE_PRIME_INTRON" "Unknown significance" "rs34254624" "This variant is a VUS because it does not have enough information."
489316 "chr21:35833044:A>G" "KCNE1" "NM_001270404:c.-50-11062T>C" "FIVE_PRIME_INTRON" "Benign" "rs180937962" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 6 694 0.0086 11 1008 0.0109 0 978 0 17 5008 0.00339457
489317 "chr21:35833045:C>T" "KCNE1" "NM_001270404:c.-50-11063G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs562234245" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
489318 "chr21:35833046:G>A" "KCNE1" "NM_001270404:c.-50-11064C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs529538356" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 1 978 0.001 3 5008 0.000599042
489319 "chr21:35833062:G>A" "KCNE1" "NM_001270404:c.-50-11080C>T" "FIVE_PRIME_INTRON" "Benign" "rs56983978" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 274 1322 0.2073 0 1006 0 11 694 0.0159 0 1008 0 0 978 0 285 5008 0.0569089
489320 "chr21:35833066:C>T" "KCNE1" "NM_001270404:c.-50-11084G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs568943645" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489321 "chr21:35833125:C>T" "KCNE1" "NM_001270404:c.-50-11143G>A" "FIVE_PRIME_INTRON" "Benign" "rs61105591" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 230 1322 0.174 0 1006 0 9 694 0.013 0 1008 0 1 978 0.001 240 5008 0.0479233
489322 "chr21:35833165:G>C" "KCNE1" "NM_001270404:c.-50-11183C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs143502356" "This variant is a VUS because it does not have enough information."
489323 "chr21:35833166:G>A" "KCNE1" "NM_001270404:c.-50-11184C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs550985997" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361
489324 "chr21:35833184:T>C" "KCNE1" "NM_001270404:c.-50-11202A>G" "FIVE_PRIME_INTRON" "Benign" "rs116290829" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 230 1322 0.174 0 1006 0 9 694 0.013 0 1008 0 0 978 0 239 5008 0.0477236
489325 "chr21:35833213:C>T" "KCNE1" "NM_001270404:c.-50-11231G>A" "FIVE_PRIME_INTRON" "Benign" "rs147175838" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 230 1322 0.174 0 1006 0 9 694 0.013 0 1008 0 0 978 0 239 5008 0.0477236
489326 "chr21:35833222:G>A" "KCNE1" "NM_001270404:c.-50-11240C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs113248847" "This variant is a VUS because it does not have enough information."
489327 "chr21:35833244:C>G" "KCNE1" "NM_001270404:c.-50-11262G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs371586176" "This variant is a VUS because it does not have enough information."
489328 "chr21:35833272:G>A" "KCNE1" "NM_001270404:c.-50-11290C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs555605095" "This variant is a VUS because it does not have enough information."
489329 "chr21:35833378:A>G" "KCNE1" "NM_001270404:c.-50-11396T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs555675309" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
489330 "chr21:35833427:C>A" "KCNE1" "NM_001270404:c.-50-11445G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs183457940" "This variant is a VUS because it does not have enough information." 0 1322 0 2 1006 0.002 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
489331 "chr21:35833442:A>C" "KCNE1" "NM_001270404:c.-50-11460T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs758461173" "This variant is a VUS because it does not have enough information."
489332 "chr21:35833443:T>C" "KCNE1" "NM_001270404:c.-50-11461A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs778051065" "This variant is a VUS because it does not have enough information."
489333 "chr21:35833466:ATG>-" "KCNE1" "NM_001270404:c.-50-11484_-50-11480delCAT" "FIVE_PRIME_INTRON" "Unknown significance" "rs770835533" "This variant is a VUS because it does not have enough information."
489334 "chr21:35833477:C>G" "KCNE1" "NM_001270404:c.-50-11495G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs747490847" "This variant is a VUS because it does not have enough information."
489335 "chr21:35833502:T>C" "KCNE1" "NM_001270404:c.-50-11520A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs538050771" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489336 "chr21:35833536:T>C" "KCNE1" "NM_001270404:c.-50-11554A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs374750067" "This variant is a VUS because it does not have enough information."
489337 "chr21:35833543:G>A" "KCNE1" "NM_001270404:c.-50-11561C>T" "FIVE_PRIME_INTRON" "Benign" "rs8133716" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 310 1322 0.2345 554 1006 0.5507 305 694 0.4395 281 1008 0.2788 484 978 0.4949 1934 5008 0.386182
489338 "chr21:35833543:G>T" "KCNE1" "NM_001270404:c.-50-11561C>A" "FIVE_PRIME_INTRON" "Benign" "rs8133716" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 61 1322 0.0461 1 1006 0.001 1 694 0.0014 0 1008 0 0 978 0 63 5008 0.0125799
489339 "chr21:35833600:C>T" "KCNE1" "NM_001270404:c.-50-11618G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs746187077" "This variant is a VUS because it does not have enough information."
489340 "chr21:35833610:T>G" "KCNE1" "NM_001270404:c.-50-11628A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs546345845" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489341 "chr21:35833646:C>G" "KCNE1" "NM_001270404:c.-50-11664G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs558266232" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
489342 "chr21:35833682:G>A" "KCNE1" "NM_001270404:c.-50-11700C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs372331619" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489343 "chr21:35833690:G>A" "KCNE1" "NM_001270404:c.-50-11708C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs376696853" "This variant is a VUS because it does not have enough information."
489344 "chr21:35833739:T>G" "KCNE1" "NM_001270404:c.-50-11757A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs188134721" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489345 "chr21:35833753:G>A" "KCNE1" "NM_001270404:c.-50-11771C>T" "FIVE_PRIME_INTRON" "Benign" "rs181319431" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 15 1322 0.0113 0 1006 0 0 694 0 0 1008 0 0 978 0 15 5008 0.00299521
489346 "chr21:35833777:C>T" "KCNE1" "NM_001270404:c.-50-11795G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs529522078" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
489347 "chr21:35833787:C>T" "KCNE1" "NM_001270404:c.-50-11805G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs544806993" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
489348 "chr21:35833799:C>T" "KCNE1" "NM_001270404:c.-50-11817G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs537756342" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
489349 "chr21:35833800:G>A" "KCNE1" "NM_001270404:c.-50-11818C>T" "FIVE_PRIME_INTRON" "Benign" "rs113793382" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 62 1322 0.0469 2 1006 0.002 1 694 0.0014 0 1008 0 1 978 0.001 66 5008 0.0131789
489350 "chr21:35833832:A>G" "KCNE1" "NM_001270404:c.-50-11850T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs545333107" "This variant is a VUS because it does not have enough information."
489351 "chr21:35833848:A>G" "KCNE1" "NM_001270404:c.-50-11866T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs775169413" "This variant is a VUS because it does not have enough information."
489352 "chr21:35833853:G>A" "KCNE1" "NM_001270404:c.-50-11871C>T" "FIVE_PRIME_INTRON" "Benign" "rs142934931" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1 1322 0.0008 10 1006 0.0099 6 694 0.0086 0 1008 0 3 978 0.0031 20 5008 0.00399361
489353 "chr21:35833859:C>A" "KCNE1" "NM_001270404:c.-50-11877G>T" "FIVE_PRIME_INTRON" "Benign" "rs73365305" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 61 1322 0.0461 1 1006 0.001 1 694 0.0014 0 1008 0 0 978 0 63 5008 0.0125799
489354 "chr21:35833877:C>T" "KCNE1" "NM_001270404:c.-50-11895G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs542678913" "This variant is a VUS because it does not have enough information."
489355 "chr21:35833915:C>A" "KCNE1" "NM_001270404:c.-50-11933G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs761734721" "This variant is a VUS because it does not have enough information."
489356 "chr21:35833943:T>C" "KCNE1" "NM_001270404:c.-50-11961A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs151105568" "This variant is a VUS because it does not have enough information." 0 1322 0 3 1006 0.003 0 694 0 1 1008 0.001 0 978 0 4 5008 0.000798722
489357 "chr21:35833975:T>C" "KCNE1" "NM_001270404:c.-50-11993A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs767500628" "This variant is a VUS because it does not have enough information."
489358 "chr21:35833992:C>A" "KCNE1" "NM_001270404:c.-50-12010G>T" "FIVE_PRIME_INTRON" "Benign" "rs117309068" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 8 1008 0.0079 0 978 0 8 5008 0.00159744
489359 "chr21:35834033:A>T" "KCNE1" "NM_001270404:c.-50-12051T>A" "FIVE_PRIME_INTRON" "Benign" "rs185396053" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 15 1322 0.0113 0 1006 0 0 694 0 0 1008 0 0 978 0 15 5008 0.00299521
489360 "chr21:35834041:T>C" "KCNE1" "NM_001270404:c.-50-12059A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs537718603" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
489361 "chr21:35834095:T>C" "KCNE1" "NM_001270404:c.-50-12113A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs750337169" "This variant is a VUS because it does not have enough information."
489362 "chr21:35834115:G>A" "KCNE1" "NM_001270404:c.-50-12133C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs139977358" "This variant is a VUS because it does not have enough information."
489363 "chr21:35834146:T>G" "KCNE1" "NM_001270404:c.-50-12164A>C" "FIVE_PRIME_INTRON" "Benign" "rs114424720" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 230 1322 0.174 0 1006 0 9 694 0.013 0 1008 0 0 978 0 239 5008 0.0477236
489364 "chr21:35834150:A>G" "KCNE1" "NM_001270404:c.-50-12168T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs766116580" "This variant is a VUS because it does not have enough information."
489365 "chr21:35834166:T>C" "KCNE1" "NM_001270404:c.-50-12184A>G" "FIVE_PRIME_INTRON" "Benign" "rs73365307" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 62 1322 0.0469 1 1006 0.001 1 694 0.0014 0 1008 0 0 978 0 64 5008 0.0127796
489366 "chr21:35834170:T>G" "KCNE1" "NM_001270404:c.-50-12188A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs538825604" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489367 "chr21:35834217:G>A" "KCNE1" "NM_001270404:c.-50-12235C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs558329652" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489368 "chr21:35834280:G>C" "KCNE1" "NM_001270404:c.-50-12298C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs369750151" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489369 "chr21:35834314:G>A" "KCNE1" "NM_001270404:c.-50-12332C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs758736849" "This variant is a VUS because it does not have enough information."
489370 "chr21:35834327:C>T" "KCNE1" "NM_001270404:c.-50-12345G>A" "FIVE_PRIME_INTRON" "Benign" "rs2000435" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 632 1322 0.4781 637 1006 0.6332 495 694 0.7133 849 1008 0.8423 616 978 0.6299 3229 5008 0.644768
489371 "chr21:35834336:G>A" "KCNE1" "NM_001270404:c.-50-12354C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs555441754" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489372 "chr21:35834355:C>T" "KCNE1" "NM_001270404:c.-50-12373G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs574298296" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489373 "chr21:35834356:G>A" "KCNE1" "NM_001270404:c.-50-12374C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs544608807" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 3 694 0.0043 0 1008 0 0 978 0 3 5008 0.000599042
489374 "chr21:35834360:C>T" "KCNE1" "NM_001270404:c.-50-12378G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs563181831" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489375 "chr21:35834366:T>C" "KCNE1" "NM_001270404:c.-50-12384A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs375429736" "This variant is a VUS because it does not have enough information."
489376 "chr21:35834369:A>T" "KCNE1" "NM_001270404:c.-50-12387T>A" "FIVE_PRIME_INTRON" "Benign" "rs73365309" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 61 1322 0.0461 1 1006 0.001 1 694 0.0014 0 1008 0 0 978 0 63 5008 0.0125799
489377 "chr21:35834370:A>G" "KCNE1" "NM_001270404:c.-50-12388T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs545195626" "This variant is a VUS because it does not have enough information." 4 1322 0.003 0 1006 0 0 694 0 0 1008 0 0 978 0 4 5008 0.000798722
489378 "chr21:35834378:C>T" "KCNE1" "NM_001270404:c.-50-12396G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs559821149" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489379 "chr21:35834391:C>T" "KCNE1" "NM_001270404:c.-50-12409G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs532434483" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489380 "chr21:35834401:G>T" "KCNE1" "NM_001270404:c.-50-12419C>A" "FIVE_PRIME_INTRON" "Benign" "rs116517418" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 230 1322 0.174 0 1006 0 9 694 0.013 0 1008 0 0 978 0 239 5008 0.0477236
489381 "chr21:35834484:A>G" "KCNE1" "NM_001270404:c.-50-12502T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs781675444" "This variant is a VUS because it does not have enough information."
489382 "chr21:35834535:T>C" "KCNE1" "NM_001270404:c.-50-12553A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs191698563" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 3 1008 0.003 0 978 0 4 5008 0.000798722
489383 "chr21:35834630:A>G" "KCNE1" "NM_001270404:c.-50-12648T>C" "FIVE_PRIME_INTRON" "Benign" "rs1003532" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 9 1322 0.0068 69 1006 0.0686 47 694 0.0677 136 1008 0.1349 62 978 0.0634 323 5008 0.0644968
489384 "chr21:35834661:C>G" "KCNE1" "NM_001270404:c.-50-12679G>C" "FIVE_PRIME_INTRON" "Benign" "rs549846075" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 0 1008 0 14 978 0.0143 14 5008 0.00279553
489385 "chr21:35834678:G>A" "KCNE1" "NM_001270404:c.-50-12696C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs530826387" "This variant is a VUS because it does not have enough information."
489386 "chr21:35834684:C>T" "KCNE1" "NM_001270404:c.-50-12702G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs780328946" "This variant is a VUS because it does not have enough information."
489387 "chr21:35834714:A>G" "KCNE1" "NM_001270404:c.-50-12732T>C" "FIVE_PRIME_INTRON" "Benign" "rs61464157" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 230 1322 0.174 0 1006 0 9 694 0.013 0 1008 0 0 978 0 239 5008 0.0477236
489388 "chr21:35834743:T>C" "KCNE1" "NM_001270404:c.-50-12761A>G" "FIVE_PRIME_INTRON" "Benign" "rs143949648" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 3 1006 0.003 0 694 0 5 1008 0.005 1 978 0.001 9 5008 0.00179712
489389 "chr21:35834744:G>A" "KCNE1" "NM_001270404:c.-50-12762C>T" "FIVE_PRIME_INTRON" "Benign" "rs60339198" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 230 1322 0.174 0 1006 0 9 694 0.013 0 1008 0 0 978 0 239 5008 0.0477236
489390 "chr21:35834780:C>A" "KCNE1" "NM_001270404:c.-50-12798G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs796276914" "This variant is a VUS because it does not have enough information."
489391 "chr21:35834829:C>T" "KCNE1" "NM_001270404:c.-50-12847G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs773837134" "This variant is a VUS because it does not have enough information."
489392 "chr21:35834837:C>G" "KCNE1" "NM_001270404:c.-50-12855G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs557671200" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489393 "chr21:35834861:T>C" "KCNE1" "NM_001270404:c.-50-12879A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs759730531" "This variant is a VUS because it does not have enough information."
489394 "chr21:35834892:T>G" "KCNE1" "NM_001270404:c.-50-12910A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs765628105" "This variant is a VUS because it does not have enough information."
489395 "chr21:35834914:G>T" "KCNE1" "NM_001270404:c.-50-12932C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs761250699" "This variant is a VUS because it does not have enough information."
489396 "chr21:35834917:T>C" "KCNE1" "NM_001270404:c.-50-12935A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs534009607" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
489397 "chr21:35834940:T>G" "KCNE1" "NM_001270404:c.-50-12958A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs181675549" "This variant is a VUS because it does not have enough information."
489398 "chr21:35834965:G>A" "KCNE1" "NM_001270404:c.-50-12983C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs555810531" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489399 "chr21:35834973:T>-" "KCNE1" "NM_001270404:c.-50-12991delA" "FIVE_PRIME_INTRON" "Benign" "rs67130304" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 244 1322 0.1846 10 1006 0.0099 14 694 0.0202 13 1008 0.0129 12 978 0.0123 293 5008 0.0585064
489400 "chr21:35834973:->T" "KCNE1" "NM_001270404:c.-50-12991_-50-12990insA" "FIVE_PRIME_INTRON" "Unknown significance" "rs200476254" "This variant is a VUS because it does not have enough information."
489401 "chr21:35834987:T>G" "KCNE1" "NM_001270404:c.-50-13005A>C" "FIVE_PRIME_INTRON" "Benign" "rs146780189" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 18 1008 0.0179 28 978 0.0286 46 5008 0.0091853
489402 "chr21:35835011:C>T" "KCNE1" "NM_001270404:c.-50-13029G>A" "FIVE_PRIME_INTRON" "Benign" "rs140545148" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 18 1008 0.0179 28 978 0.0286 46 5008 0.0091853
489403 "chr21:35835028:C>T" "KCNE1" "NM_001270404:c.-50-13046G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs771571616" "This variant is a VUS because it does not have enough information."
489404 "chr21:35835041:A>G" "KCNE1" "NM_001270404:c.-50-13059T>C" "FIVE_PRIME_INTRON" "Benign" "rs187268680" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 7 1322 0.0053 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 8 5008 0.00159744
489405 "chr21:35835042:T>C" "KCNE1" "NM_001270404:c.-50-13060A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs773157597" "This variant is a VUS because it does not have enough information."
489406 "chr21:35835046:T>C" "KCNE1" "NM_001270404:c.-50-13064A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs577872839" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489407 "chr21:35835085:G>A" "KCNE1" "NM_001270404:c.-50-13103C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs760549143" "This variant is a VUS because it does not have enough information."
489408 "chr21:35835087:C>T" "KCNE1" "NM_001270404:c.-50-13105G>A" "FIVE_PRIME_INTRON" "Benign" "rs117988475" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 18 1008 0.0179 42 978 0.0429 60 5008 0.0119808
489409 "chr21:35835102:G>A" "KCNE1" "NM_001270404:c.-50-13120C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs377746562" "This variant is a VUS because it does not have enough information."
489410 "chr21:35835148:G>A" "KCNE1" "NM_001270404:c.-50-13166C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs766169197" "This variant is a VUS because it does not have enough information."
489411 "chr21:35835175:A>-" "KCNE1" "NM_001270404:c.-50-13193delT" "FIVE_PRIME_INTRON" "Unknown significance" "rs754787639" "This variant is a VUS because it does not have enough information."
489412 "chr21:35835183:C>T" "KCNE1" "NM_001270404:c.-50-13201G>A" "FIVE_PRIME_INTRON" "Benign" "rs71329068" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 44 1322 0.0333 176 1006 0.175 109 694 0.1571 148 1008 0.1468 114 978 0.1166 591 5008 0.118011
489413 "chr21:35835224:C>G" "KCNE1" "NM_001270404:c.-50-13242G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs758924458" "This variant is a VUS because it does not have enough information."
489414 "chr21:35835232:C>G" "KCNE1" "NM_001270404:c.-50-13250G>C" "FIVE_PRIME_INTRON" "Benign" "rs76996258" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 230 1322 0.174 0 1006 0 9 694 0.013 0 1008 0 0 978 0 239 5008 0.0477236
489415 "chr21:35835239:T>C" "KCNE1" "NM_001270404:c.-50-13257A>G" "FIVE_PRIME_INTRON" "Benign" "rs145672004" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 5 1008 0.005 0 978 0 5 5008 0.000998403
489416 "chr21:35835253:A>T" "KCNE1" "NM_001270404:c.-50-13271T>A" "FIVE_PRIME_INTRON" "Benign" "rs192127251" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 8 694 0.0115 0 1008 0 3 978 0.0031 11 5008 0.00219649
489417 "chr21:35835291:C>G" "KCNE1" "NM_001270404:c.-50-13309G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs146583256" "This variant is a VUS because it does not have enough information."
489418 "chr21:35835323:T>C" "KCNE1" "NM_001270404:c.-50-13341A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs531254808" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489419 "chr21:35835376:A>G" "KCNE1" "NM_001270404:c.-50-13394T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs182588459" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
489420 "chr21:35835380:G>A" "KCNE1" "NM_001270404:c.-50-13398C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs751835532" "This variant is a VUS because it does not have enough information."
489421 "chr21:35835410:A>C" "KCNE1" "NM_001270404:c.-50-13428T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs565187439" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489422 "chr21:35835497:G>A" "KCNE1" "NM_001270404:c.-50-13515C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs557390782" "This variant is a VUS because it does not have enough information."
489423 "chr21:35835531:->T" "KCNE1" "NM_001270404:c.-50-13549_-50-13548insA" "FIVE_PRIME_INTRON" "Benign" "rs11458029" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 880 1322 0.6657 702 1006 0.6978 545 694 0.7853 972 1008 0.9643 670 978 0.6851 3769 5008 0.752596
489424 "chr21:35835548:A>G" "KCNE1" "NM_001270404:c.-50-13566T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs781154715" "This variant is a VUS because it does not have enough information."
489425 "chr21:35835560:G>A" "KCNE1" "NM_001270404:c.-50-13578C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs542264100" "This variant is a VUS because it does not have enough information."
489426 "chr21:35835568:G>C" "KCNE1" "NM_001270404:c.-50-13586C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs750921874" "This variant is a VUS because it does not have enough information."
489427 "chr21:35835577:G>A" "KCNE1" "NM_001270404:c.-50-13595C>T" "FIVE_PRIME_INTRON" "Benign" "rs186976554" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 9 1006 0.0089 0 694 0 0 1008 0 0 978 0 9 5008 0.00179712
489428 "chr21:35835586:C>A" "KCNE1" "NM_001270404:c.-50-13604G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs547634762" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489429 "chr21:35835587:G>A" "KCNE1" "NM_001270404:c.-50-13605C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs572970363" "This variant is a VUS because it does not have enough information."
489430 "chr21:35835589:C>T" "KCNE1" "NM_001270404:c.-50-13607G>A" "FIVE_PRIME_INTRON" "Benign" "rs7283711" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 894 1322 0.6762 708 1006 0.7038 553 694 0.7968 985 1008 0.9772 677 978 0.6922 3817 5008 0.762181
489431 "chr21:35835635:C>T" "KCNE1" "NM_001270404:c.-50-13653G>A" "FIVE_PRIME_INTRON" "Benign" "rs7278393" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 632 1322 0.4781 639 1006 0.6352 497 694 0.7161 849 1008 0.8423 616 978 0.6299 3233 5008 0.645567
489432 "chr21:35835645:C>T" "KCNE1" "NM_001270404:c.-50-13663G>A" "FIVE_PRIME_INTRON" "Benign" "rs59785817" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 9 1322 0.0068 69 1006 0.0686 47 694 0.0677 136 1008 0.1349 61 978 0.0624 322 5008 0.0642971
489433 "chr21:35835646:G>A" "KCNE1" "NM_001270404:c.-50-13664C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs567748093" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489434 "chr21:35835649:A>G" "KCNE1" "NM_001270404:c.-50-13667T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs537857019" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489435 "chr21:35835671:C>T" "KCNE1" "NM_001270404:c.-50-13689G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs755701874" "This variant is a VUS because it does not have enough information."
489436 "chr21:35835675:A>G" "KCNE1" "NM_001270404:c.-50-13693T>C" "FIVE_PRIME_INTRON" "Benign" "rs149072620" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 10 1322 0.0076 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 12 5008 0.00239617
489437 "chr21:35835738:C>T" "KCNE1" "NM_001270404:c.-50-13756G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs544464266" "This variant is a VUS because it does not have enough information."
489438 "chr21:35835767:G>A" "KCNE1" "NM_001270404:c.-50-13785C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs189814409" "This variant is a VUS because it does not have enough information." 4 1322 0.003 0 1006 0 0 694 0 0 1008 0 0 978 0 4 5008 0.000798722
489439 "chr21:35835780:T>G" "KCNE1" "NM_001270404:c.-50-13798A>C" "FIVE_PRIME_INTRON" "Benign" "rs115024339" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 230 1322 0.174 0 1006 0 9 694 0.013 0 1008 0 0 978 0 239 5008 0.0477236
489440 "chr21:35835793:G>A" "KCNE1" "NM_001270404:c.-50-13811C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs377695904" "This variant is a VUS because it does not have enough information."
489441 "chr21:35835795:G>A" "KCNE1" "NM_001270404:c.-50-13813C>T" "FIVE_PRIME_INTRON" "Benign" "rs114160904" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 40 1322 0.0303 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 42 5008 0.00838658
489442 "chr21:35835841:CT>-" "KCNE1" "NM_001270404:c.-50-13859_-50-13856delAG" "FIVE_PRIME_INTRON" "Benign" "rs530889411" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1 1322 0.0008 6 1006 0.006 0 694 0 0 1008 0 0 978 0 7 5008 0.00139776
489443 "chr21:35835843:G>C" "KCNE1" "NM_001270404:c.-50-13861C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs747828639" "This variant is a VUS because it does not have enough information."
489444 "chr21:35835846:G>A" "KCNE1" "NM_001270404:c.-50-13864C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs572591175" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489445 "chr21:35835869:C>T" "KCNE1" "NM_001270404:c.-50-13887G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs543201120" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489446 "chr21:35835869:C>A" "KCNE1" "NM_001270404:c.-50-13887G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs543201120" "This variant is a VUS because it does not have enough information."
489447 "chr21:35835882:G>A" "KCNE1" "NM_001270404:c.-50-13900C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs143138216" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489448 "chr21:35835910:C>-" "KCNE1" "NM_001270404:c.-50-13928delG" "FIVE_PRIME_INTRON" "Unknown significance" "rs549106346" "This variant is a VUS because it does not have enough information."
489449 "chr21:35835910:C>A" "KCNE1" "NM_001270404:c.-50-13928G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs576045814" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489450 "chr21:35835915:A>G" "KCNE1" "NM_001270404:c.-50-13933T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs543457130" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489451 "chr21:35835955:C>T" "KCNE1" "NM_001270404:c.-50-13973G>A" "FIVE_PRIME_INTRON" "Benign" "rs75731778" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 230 1322 0.174 0 1006 0 9 694 0.013 0 1008 0 0 978 0 239 5008 0.0477236
489452 "chr21:35835967:G>A" "KCNE1" "NM_001270404:c.-50-13985C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs768723316" "This variant is a VUS because it does not have enough information."
489453 "chr21:35835971:G>T" "KCNE1" "NM_001270404:c.-50-13989C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs778797273" "This variant is a VUS because it does not have enough information."
489454 "chr21:35835977:A>G" "KCNE1" "NM_001270404:c.-50-13995T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs79724883" "This variant is a VUS because it does not have enough information."
489455 "chr21:35835984:T>C" "KCNE1" "NM_001270404:c.-50-14002A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs532124580" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489456 "chr21:35835986:T>-" "KCNE1" "NM_001270404:c.-50-14004delA" "FIVE_PRIME_INTRON" "Unknown significance" "rs370960013" "This variant is a VUS because it does not have enough information."
489457 "chr21:35835989:C>-" "KCNE1" "NM_001270404:c.-50-14007delG" "FIVE_PRIME_INTRON" "Benign" "rs151178878" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 10 1322 0.0076 70 1006 0.0696 48 694 0.0692 137 1008 0.1359 61 978 0.0624 326 5008 0.0650958
489458 "chr21:35835993:C>A" "KCNE1" "NM_001270404:c.-50-14011G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs182805444" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489459 "chr21:35836014:T>C" "KCNE1" "NM_001270404:c.-50-14032A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs559678283" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489460 "chr21:35836021:G>T" "KCNE1" "NM_001270404:c.-50-14039C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs553321180" "This variant is a VUS because it does not have enough information."
489461 "chr21:35836034:T>C" "KCNE1" "NM_001270404:c.-50-14052A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs771560432" "This variant is a VUS because it does not have enough information."
489462 "chr21:35836040:G>T" "KCNE1" "NM_001270404:c.-50-14058C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs529896584" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
489463 "chr21:35836046:G>A" "KCNE1" "NM_001270404:c.-50-14064C>T" "FIVE_PRIME_INTRON" "Benign" "rs116599785" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 39 1322 0.0295 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 41 5008 0.0081869
489464 "chr21:35836056:G>A" "KCNE1" "NM_001270404:c.-50-14074C>T" "FIVE_PRIME_INTRON" "Benign" "rs148258003" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 18 1008 0.0179 28 978 0.0286 46 5008 0.0091853
489465 "chr21:35836087:C>G" "KCNE1" "NM_001270404:c.-50-14105G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs141346977" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489466 "chr21:35836121:T>C" "KCNE1" "NM_001270404:c.-50-14139A>G" "FIVE_PRIME_INTRON" "Benign" "rs57121143" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 253 1322 0.1914 0 1006 0 9 694 0.013 0 1008 0 0 978 0 262 5008 0.0523163
489467 "chr21:35836125:G>A" "KCNE1" "NM_001270404:c.-50-14143C>T" "FIVE_PRIME_INTRON" "Benign" "rs79409180" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 6 1006 0.006 0 694 0 0 1008 0 0 978 0 6 5008 0.00119808
489468 "chr21:35836130:T>G" "KCNE1" "NM_001270404:c.-50-14148A>C" "FIVE_PRIME_INTRON" "Benign" "rs538635929" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 5 1008 0.005 0 978 0 5 5008 0.000998403
489469 "chr21:35836157:T>A" "KCNE1" "NM_001270404:c.-50-14175A>T" "FIVE_PRIME_INTRON" "Benign" "rs11088285" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 631 1322 0.4773 639 1006 0.6352 497 694 0.7161 849 1008 0.8423 616 978 0.6299 3232 5008 0.645367
489470 "chr21:35836159:G>A" "KCNE1" "NM_001270404:c.-50-14177C>T" "FIVE_PRIME_INTRON" "Benign" "rs59847762" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 23 1322 0.0174 0 1006 0 0 694 0 0 1008 0 0 978 0 23 5008 0.00459265
489471 "chr21:35836213:T>A" "KCNE1" "NM_001270404:c.-50-14231A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs536454975" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489472 "chr21:35836223:T>C" "KCNE1" "NM_001270404:c.-50-14241A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs187089592" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 4 1008 0.004 0 978 0 4 5008 0.000798722
489473 "chr21:35836226:T>G" "KCNE1" "NM_001270404:c.-50-14244A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs759342088" "This variant is a VUS because it does not have enough information."
489474 "chr21:35836242:C>T" "KCNE1" "NM_001270404:c.-50-14260G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs192952419" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489475 "chr21:35836264:G>A" "KCNE1" "NM_001270404:c.-50-14282C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs543570706" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489476 "chr21:35836287:C>G" "KCNE1" "NM_001270404:c.-50-14305G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs558671024" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489477 "chr21:35836328:G>A" "KCNE1" "NM_001270404:c.-50-14346C>T" "FIVE_PRIME_INTRON" "Benign" "rs62211543" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 3 1322 0.0023 21 1006 0.0209 4 694 0.0058 0 1008 0 4 978 0.0041 32 5008 0.00638978
489478 "chr21:35836345:T>A" "KCNE1" "NM_001270404:c.-50-14363A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs183545619" "This variant is a VUS because it does not have enough information."
489479 "chr21:35836372:A>C" "KCNE1" "NM_001270404:c.-50-14390T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs774669431" "This variant is a VUS because it does not have enough information."
489480 "chr21:35836377:->C" "KCNE1" "NM_001270404:c.-50-14395_-50-14394insG" "FIVE_PRIME_INTRON" "Unknown significance" "rs34805507" "This variant is a VUS because it does not have enough information."
489481 "chr21:35836387:T>C" "KCNE1" "NM_001270404:c.-50-14405A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs762178057" "This variant is a VUS because it does not have enough information."
489482 "chr21:35836396:T>A" "KCNE1" "NM_001270404:c.-50-14414A>T" "FIVE_PRIME_INTRON" "Benign" "rs143436088" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 34 1322 0.0257 3 1006 0.003 7 694 0.0101 0 1008 0 0 978 0 44 5008 0.00878594
489483 "chr21:35836420:C>T" "KCNE1" "NM_001270404:c.-50-14438G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs188776847" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
489484 "chr21:35836428:A>G" "KCNE1" "NM_001270404:c.-50-14446T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs529961708" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489485 "chr21:35836430:C>T" "KCNE1" "NM_001270404:c.-50-14448G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs750532811" "This variant is a VUS because it does not have enough information."
489486 "chr21:35836435:C>A" "KCNE1" "NM_001270404:c.-50-14453G>T" "FIVE_PRIME_INTRON" "Benign" "rs541677214" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 0 1008 0 14 978 0.0143 14 5008 0.00279553
489487 "chr21:35836444:->A" "KCNE1" "NM_001270404:c.-50-14462_-50-14461insT" "FIVE_PRIME_INTRON" "Unknown significance" "rs34955621" "This variant is a VUS because it does not have enough information."
489488 "chr21:35836445:C>T" "KCNE1" "NM_001270404:c.-50-14463G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs563472161" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489489 "chr21:35836452:C>A" "KCNE1" "NM_001270404:c.-50-14470G>T" "FIVE_PRIME_INTRON" "Benign" "rs117425918" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1 1322 0.0008 10 1006 0.0099 4 694 0.0058 0 1008 0 39 978 0.0399 54 5008 0.0107827
489490 "chr21:35836462:T>A" "KCNE1" "NM_001270404:c.-50-14480A>T" "FIVE_PRIME_INTRON" "Benign" "rs549900768" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 0 1008 0 5 978 0.0051 5 5008 0.000998403
489491 "chr21:35836508:G>C" "KCNE1" "NM_001270404:c.-50-14526C>G" "FIVE_PRIME_INTRON" "Benign" "rs34282217" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 4 1322 0.003 88 1006 0.0875 34 694 0.049 0 1008 0 39 978 0.0399 165 5008 0.0329473
489492 "chr21:35836558:C>T" "KCNE1" "NM_001270404:c.-50-14576G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs763383327" "This variant is a VUS because it does not have enough information."
489493 "chr21:35836564:G>A" "KCNE1" "NM_001270404:c.-50-14582C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs193296938" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 1 1008 0.001 0 978 0 2 5008 0.000399361
489494 "chr21:35836566:G>C" "KCNE1" "NM_001270404:c.-50-14584C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs547344526" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489495 "chr21:35836599:G>A" "KCNE1" "NM_001270404:c.-50-14617C>T" "FIVE_PRIME_INTRON" "Benign" "rs41314743" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 313 1322 0.2368 86 1006 0.0855 192 694 0.2767 568 1008 0.5635 131 978 0.1339 1290 5008 0.257588
489496 "chr21:35836614:C>T" "KCNE1" "NM_001270404:c.-50-14632G>A" "FIVE_PRIME_INTRON" "Benign" "rs115792121" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 15 1322 0.0113 0 1006 0 0 694 0 0 1008 0 0 978 0 15 5008 0.00299521
489497 "chr21:35836619:C>T" "KCNE1" "NM_001270404:c.-50-14637G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs565069734" "This variant is a VUS because it does not have enough information."
489498 "chr21:35836620:G>A" "KCNE1" "NM_001270404:c.-50-14638C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs554941608" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489499 "chr21:35836698:A>G" "KCNE1" "NM_001270404:c.-50-14716T>C" "FIVE_PRIME_INTRON" "Benign" "rs1007293" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1288 1322 0.9743 729 1006 0.7247 580 694 0.8357 1005 1008 0.997 754 978 0.771 4356 5008 0.869808
489500 "chr21:35836767:A>G" "KCNE1" "NM_001270404:c.-50-14785T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs537633314" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 1 1006 0.001 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
489501 "chr21:35836819:A>G" "KCNE1" "NM_001270404:c.-50-14837T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs74594239" "This variant is a VUS because it does not have enough information."
489502 "chr21:35836824:C>G" "KCNE1" "NM_001270404:c.-50-14842G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs558734324" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489503 "chr21:35836886:C>-" "KCNE1" "NM_001270404:c.-50-14904delG" "FIVE_PRIME_INTRON" "Benign" "rs5843661" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 9 1322 0.0068 69 1006 0.0686 47 694 0.0677 136 1008 0.1349 61 978 0.0624 322 5008 0.0642971
489504 "chr21:35836886:->C" "KCNE1" "NM_001270404:c.-50-14904_-50-14903insG" "FIVE_PRIME_INTRON" "Unknown significance" "rs72550278" "This variant is a VUS because it does not have enough information."
489505 "chr21:35836889:C>T" "KCNE1" "NM_001270404:c.-50-14907G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs576968306" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489506 "chr21:35836905:C>T" "KCNE1" "NM_001270404:c.-50-14923G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs767056536" "This variant is a VUS because it does not have enough information."
489507 "chr21:35836926:G>T" "KCNE1" "NM_001270404:c.-50-14944C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs777325208" "This variant is a VUS because it does not have enough information."
489508 "chr21:35836927:G>T" "KCNE1" "NM_001270404:c.-50-14945C>A" "FIVE_PRIME_INTRON" "Benign" "rs41314827" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 23 1322 0.0174 0 1006 0 0 694 0 0 1008 0 0 978 0 23 5008 0.00459265
489509 "chr21:35836957:G>C" "KCNE1" "NM_001270404:c.-50-14975C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs558703960" "This variant is a VUS because it does not have enough information."
489510 "chr21:35837000:C>T" "KCNE1" "NM_001270404:c.-50-15018G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs577071465" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 4 978 0.0041 4 5008 0.000798722
489511 "chr21:35837027:C>T" "KCNE1" "NM_001270404:c.-50-15045G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs139517714" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489512 "chr21:35837056:A>G" "KCNE1" "NM_001270404:c.-50-15074T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs776674573" "This variant is a VUS because it does not have enough information."
489513 "chr21:35837078:A>G" "KCNE1" "NM_001270404:c.-50-15096T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs542137975" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489514 "chr21:35837093:A>C" "KCNE1" "NM_001270404:c.-50-15111T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs41315445" "This variant is a VUS because it does not have enough information."
489515 "chr21:35837099:T>C" "KCNE1" "NM_001270404:c.-50-15117A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs540719061" "This variant is a VUS because it does not have enough information."
489516 "chr21:35837113:A>G" "KCNE1" "NM_001270404:c.-50-15131T>C" "FIVE_PRIME_INTRON" "Benign" "rs4384872" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 9 1322 0.0068 69 1006 0.0686 47 694 0.0677 136 1008 0.1349 61 978 0.0624 322 5008 0.0642971
489517 "chr21:35837118:T>C" "KCNE1" "NM_001270404:c.-50-15136A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs575141063" "This variant is a VUS because it does not have enough information." 4 1322 0.003 0 1006 0 0 694 0 0 1008 0 0 978 0 4 5008 0.000798722
489518 "chr21:35837123:G>T" "KCNE1" "NM_001270404:c.-50-15141C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs545545487" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 3 978 0.0031 3 5008 0.000599042
489519 "chr21:35837126:C>T" "KCNE1" "NM_001270404:c.-50-15144G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs769692799" "This variant is a VUS because it does not have enough information."
489520 "chr21:35837128:G>A" "KCNE1" "NM_001270404:c.-50-15146C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs565046806" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489521 "chr21:35837132:A>G" "KCNE1" "NM_001270404:c.-50-15150T>C" "FIVE_PRIME_INTRON" "Benign" "rs532435167" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 6 1008 0.006 0 978 0 6 5008 0.00119808
489522 "chr21:35837160:T>G" "KCNE1" "NM_001270404:c.-50-15178A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs562751289" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489523 "chr21:35837185:A>G" "KCNE1" "NM_001270404:c.-50-15203T>C" "FIVE_PRIME_INTRON" "Benign" "rs559724880" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 6 1008 0.006 0 978 0 6 5008 0.00119808
489524 "chr21:35837233:T>G" "KCNE1" "NM_001270404:c.-50-15251A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs574637169" "This variant is a VUS because it does not have enough information."
489525 "chr21:35837235:C>A" "KCNE1" "NM_001270404:c.-50-15253G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs529823777" "This variant is a VUS because it does not have enough information."
489526 "chr21:35837261:A>G" "KCNE1" "NM_001270404:c.-50-15279T>C" "FIVE_PRIME_INTRON" "Benign" "rs530027835" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 0 1008 0 5 978 0.0051 5 5008 0.000998403
489527 "chr21:35837290:C>T" "KCNE1" "NM_001270404:c.-50-15308G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs779550949" "This variant is a VUS because it does not have enough information."
489528 "chr21:35837319:A>G" "KCNE1" "NM_001270404:c.-50-15337T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs548904137" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489529 "chr21:35837359:A>G" "KCNE1" "NM_001270404:c.-50-15377T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs775467320" "This variant is a VUS because it does not have enough information."
489530 "chr21:35837361:C>T" "KCNE1" "NM_001270404:c.-50-15379G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs570251038" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361
489531 "chr21:35837402:G>A" "KCNE1" "NM_001270404:c.-50-15420C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs537647363" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 3 978 0.0031 3 5008 0.000599042
489532 "chr21:35837408:A>-" "KCNE1" "NM_001270404:c.-50-15426delT" "FIVE_PRIME_INTRON" "Benign" "rs139457556" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 24 1322 0.0182 0 1006 0 0 694 0 0 1008 0 0 978 0 24 5008 0.00479233
489533 "chr21:35837459:A>G" "KCNE1" "NM_001270404:c.-50-15477T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs552766306" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
489534 "chr21:35837463:T>C" "KCNE1" "NM_001270404:c.-50-15481A>G" "FIVE_PRIME_INTRON" "Benign" "rs116687371" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 23 1322 0.0174 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 25 5008 0.00499201
489535 "chr21:35837481:C>T" "KCNE1" "NM_001270404:c.-50-15499G>A" "FIVE_PRIME_INTRON" "Benign" "rs76351786" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 117 1322 0.0885 1 1006 0.001 4 694 0.0058 38 1008 0.0377 39 978 0.0399 199 5008 0.0397364
489536 "chr21:35837491:C>T" "KCNE1" "NM_001270404:c.-50-15509G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs552774256" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489537 "chr21:35837531:C>G" "KCNE1" "NM_001270404:c.-50-15549G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs78795089" "This variant is a VUS because it does not have enough information."
489538 "chr21:35837532:C>T" "KCNE1" "NM_001270404:c.-50-15550G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs574411599" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489539 "chr21:35837552:T>C" "KCNE1" "NM_001270404:c.-50-15570A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs767686333" "This variant is a VUS because it does not have enough information."
489540 "chr21:35837567:C>A" "KCNE1" "NM_001270404:c.-50-15585G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs773493088" "This variant is a VUS because it does not have enough information."
489541 "chr21:35837581:C>T" "KCNE1" "NM_001270404:c.-50-15599G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs760601841" "This variant is a VUS because it does not have enough information."
489542 "chr21:35837586:G>C" "KCNE1" "NM_001270404:c.-50-15604C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs80245629" "This variant is a VUS because it does not have enough information."
489543 "chr21:35837620:A>G" "KCNE1" "NM_001270404:c.-50-15638T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs535099242" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489544 "chr21:35837646:A>G" "KCNE1" "NM_001270404:c.-50-15664T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs557223293" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489545 "chr21:35837674:C>T" "KCNE1" "NM_001270404:c.-50-15692G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs74903531" "This variant is a VUS because it does not have enough information."
489546 "chr21:35837690:T>C" "KCNE1" "NM_001270404:c.-50-15708A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs575153477" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361
489547 "chr21:35837707:C>A" "KCNE1" "NM_001270404:c.-50-15725G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs766510477" "This variant is a VUS because it does not have enough information."
489548 "chr21:35837749:T>C" "KCNE1" "NM_001270404:c.-50-15767A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs768525439" "This variant is a VUS because it does not have enough information."
489549 "chr21:35837760:C>G" "KCNE1" "NM_001270404:c.-50-15778G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs753416307" "This variant is a VUS because it does not have enough information."
489550 "chr21:35837783:T>C" "KCNE1" "NM_001270404:c.-50-15801A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs560923343" "This variant is a VUS because it does not have enough information."
489551 "chr21:35837794:A>C" "KCNE1" "NM_001270404:c.-50-15812T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs371976215" "This variant is a VUS because it does not have enough information."
489552 "chr21:35837801:C>G" "KCNE1" "NM_001270404:c.-50-15819G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs184664668" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
489553 "chr21:35837806:C>T" "KCNE1" "NM_001270404:c.-50-15824G>A" "FIVE_PRIME_INTRON" "Benign" "rs8131017" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 126 1322 0.0953 376 1006 0.3738 191 694 0.2752 95 1008 0.0942 334 978 0.3415 1122 5008 0.224042
489554 "chr21:35837807:G>A" "KCNE1" "NM_001270404:c.-50-15825C>T" "FIVE_PRIME_INTRON" "Benign" "rs77412320" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 14 1322 0.0106 0 1006 0 0 694 0 0 1008 0 4 978 0.0041 18 5008 0.00359425
489555 "chr21:35837808:C>A" "KCNE1" "NM_001270404:c.-50-15826G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs531041061" "This variant is a VUS because it does not have enough information."
489556 "chr21:35837814:G>A" "KCNE1" "NM_001270404:c.-50-15832C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs541549327" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489557 "chr21:35837819:A>G" "KCNE1" "NM_001270404:c.-50-15837T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs765553161" "This variant is a VUS because it does not have enough information."
489558 "chr21:35837925:G>A" "KCNE1" "NM_001270404:c.-50-15943C>T" "FIVE_PRIME_INTRON" "Benign" "rs6517230" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 852 1322 0.6445 639 1006 0.6352 506 694 0.7291 849 1008 0.8423 619 978 0.6329 3465 5008 0.691893
489559 "chr21:35837934:A>G" "KCNE1" "NM_001270404:c.-50-15952T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs530156632" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489560 "chr21:35837978:A>G" "KCNE1" "NM_001270404:c.-50-15996T>C" "FIVE_PRIME_INTRON" "Benign" "rs149282070" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 13 1322 0.0098 0 1006 0 0 694 0 0 1008 0 0 978 0 13 5008 0.00259585
489561 "chr21:35838006:C>T" "KCNE1" "NM_001270404:c.-50-16024G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs563982492" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489562 "chr21:35838046:G>A" "KCNE1" "NM_001270404:c.-50-16064C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs531197916" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489563 "chr21:35838060:A>C" "KCNE1" "NM_001270404:c.-50-16078T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs191191112" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489564 "chr21:35838076:T>G" "KCNE1" "NM_001270404:c.-50-16094A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs565044896" "This variant is a VUS because it does not have enough information."
489565 "chr21:35838080:T>A" "KCNE1" "NM_001270404:c.-50-16098A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs114510427" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489566 "chr21:35838115:A>G" "KCNE1" "NM_001270404:c.-50-16133T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs758805016" "This variant is a VUS because it does not have enough information."
489567 "chr21:35838128:G>A" "KCNE1" "NM_001270404:c.-50-16146C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs777225747" "This variant is a VUS because it does not have enough information."
489568 "chr21:35838138:G>C" "KCNE1" "NM_001270404:c.-50-16156C>G" "FIVE_PRIME_INTRON" "Benign" "rs79009797" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 32 1322 0.0242 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 34 5008 0.00678914
489569 "chr21:35838203:C>T" "KCNE1" "NM_001270404:c.-50-16221G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs546718971" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489570 "chr21:35838204:A>T" "KCNE1" "NM_001270404:c.-50-16222T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs184063692" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 3 694 0.0043 0 1008 0 0 978 0 3 5008 0.000599042
489571 "chr21:35838217:C>A" "KCNE1" "NM_001270404:c.-50-16235G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs189708744" "This variant is a VUS because it does not have enough information." 0 1322 0 3 1006 0.003 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042
489572 "chr21:35838224:C>T" "KCNE1" "NM_001270404:c.-50-16242G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs747923764" "This variant is a VUS because it does not have enough information."
489573 "chr21:35838236:G>C" "KCNE1" "NM_001270404:c.-50-16254C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs144335878" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361
489574 "chr21:35838263:A>C" "KCNE1" "NM_001270404:c.-50-16281T>G" "FIVE_PRIME_INTRON" "Benign" "rs369107752" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 38 978 0.0389 39 5008 0.00778754
489575 "chr21:35838267:G>A" "KCNE1" "NM_001270404:c.-50-16285C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs771948693" "This variant is a VUS because it does not have enough information."
489576 "chr21:35838274:A>G" "KCNE1" "NM_001270404:c.-50-16292T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs539376599" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
489577 "chr21:35838361:G>T" "KCNE1" "NM_001270404:c.-50-16379C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs557614515" "This variant is a VUS because it does not have enough information." 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042
489578 "chr21:35838370:->A" "KCNE1" "NM_001270404:c.-50-16388_-50-16387insT" "FIVE_PRIME_INTRON" "Unknown significance" "rs777448415" "This variant is a VUS because it does not have enough information."
489579 "chr21:35838424:G>A" "KCNE1" "NM_001270404:c.-50-16442C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs181750928" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489580 "chr21:35838465:T>C" "KCNE1" "NM_001270404:c.-50-16483A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs540052187" "This variant is a VUS because it does not have enough information." 0 1322 0 2 1006 0.002 2 694 0.0029 0 1008 0 0 978 0 4 5008 0.000798722
489581 "chr21:35838471:C>T" "KCNE1" "NM_001270404:c.-50-16489G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs780902371" "This variant is a VUS because it does not have enough information."
489582 "chr21:35838505:G>A" "KCNE1" "NM_001270404:c.-50-16523C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs745771066" "This variant is a VUS because it does not have enough information."
489583 "chr21:35838532:C>A" "KCNE1" "NM_001270404:c.-50-16550G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs553437262" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489584 "chr21:35838533:T>C" "KCNE1" "NM_001270404:c.-50-16551A>G" "FIVE_PRIME_INTRON" "Benign" "rs10211948" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1298 1322 0.9818 729 1006 0.7247 581 694 0.8372 1005 1008 0.997 754 978 0.771 4367 5008 0.872005
489585 "chr21:35838637:C>T" "KCNE1" "NM_001270404:c.-50-16655G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs117174947" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489586 "chr21:35838664:T>C" "KCNE1" "NM_001270404:c.-50-16682A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs779978359" "This variant is a VUS because it does not have enough information."
489587 "chr21:35838760:T>G" "KCNE1" "NM_001270404:c.-50-16778A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs78591344" "This variant is a VUS because it does not have enough information."
489588 "chr21:35838802:G>T" "KCNE1" "NM_001270404:c.-50-16820C>A" "FIVE_PRIME_INTRON" "Benign" "rs12053737" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 317 1322 0.2398 86 1006 0.0855 192 694 0.2767 568 1008 0.5635 131 978 0.1339 1294 5008 0.258387
489589 "chr21:35838831:T>C" "KCNE1" "NM_001270404:c.-50-16849A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs186780495" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
489590 "chr21:35838851:ATTTCCT>-" "KCNE1" "NM_001270404:c.-50-16869_-50-16861delAGGAAAT" "FIVE_PRIME_INTRON" "Benign" "rs149668718" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 117 1322 0.0885 1 1006 0.001 4 694 0.0058 38 1008 0.0377 39 978 0.0399 199 5008 0.0397364
489591 "chr21:35838880:T>A" "KCNE1" "NM_001270404:c.-50-16898A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs372948802" "This variant is a VUS because it does not have enough information."
489592 "chr21:35838888:T>C" "KCNE1" "NM_001270404:c.-50-16906A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs546531959" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489593 "chr21:35838905:A>C" "KCNE1" "NM_001270404:c.-50-16923T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs564726010" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489594 "chr21:35838907:G>T" "KCNE1" "NM_001270404:c.-50-16925C>A" "FIVE_PRIME_INTRON" "Benign" "rs1007294" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1134 1322 0.8578 708 1006 0.7038 563 694 0.8112 1005 1008 0.997 726 978 0.7423 4136 5008 0.825879
489595 "chr21:35838932:C>T" "KCNE1" "NM_001270404:c.-50-16950G>A" "FIVE_PRIME_INTRON" "Benign" "rs148777812" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 5 1006 0.005 3 694 0.0043 23 1008 0.0228 0 978 0 31 5008 0.0061901
489596 "chr21:35838933:G>A" "KCNE1" "NM_001270404:c.-50-16951C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs760973869" "This variant is a VUS because it does not have enough information."
489597 "chr21:35838963:T>C" "KCNE1" "NM_001270404:c.-50-16981A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs570885530" "This variant is a VUS because it does not have enough information."
489598 "chr21:35838984:C>G" "KCNE1" "NM_001270404:c.-50-17002G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs770974810" "This variant is a VUS because it does not have enough information."
489599 "chr21:35838993:G>T" "KCNE1" "NM_001270404:c.-50-17011C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs568183910" "This variant is a VUS because it does not have enough information." 4 1322 0.003 0 1006 0 0 694 0 0 1008 0 0 978 0 4 5008 0.000798722
489600 "chr21:35838998:G>T" "KCNE1" "NM_001270404:c.-50-17016C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs776730179" "This variant is a VUS because it does not have enough information."
489601 "chr21:35838999:C>G" "KCNE1" "NM_001270404:c.-50-17017G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs143884791" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
489602 "chr21:35839017:T>C" "KCNE1" "NM_001270404:c.-50-17035A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs550233651" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489603 "chr21:35839019:A>G" "KCNE1" "NM_001270404:c.-50-17037T>C" "FIVE_PRIME_INTRON" "Benign" "rs73365315" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 23 1322 0.0174 0 1006 0 0 694 0 0 1008 0 0 978 0 23 5008 0.00459265
489604 "chr21:35839042:A>C" "KCNE1" "NM_001270404:c.-50-17060T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs760024344" "This variant is a VUS because it does not have enough information."
489605 "chr21:35839067:C>T" "KCNE1" "NM_001270404:c.-50-17085G>A" "FIVE_PRIME_INTRON" "Benign" "rs1007295" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 875 1322 0.6619 639 1006 0.6352 506 694 0.7291 849 1008 0.8423 619 978 0.6329 3488 5008 0.696486
489606 "chr21:35839068:G>A" "KCNE1" "NM_001270404:c.-50-17086C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs753207848" "This variant is a VUS because it does not have enough information."
489607 "chr21:35839107:T>G" "KCNE1" "NM_001270404:c.-50-17125A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs761255279" "This variant is a VUS because it does not have enough information."
489608 "chr21:35839129:G>T" "KCNE1" "NM_001270404:c.-50-17147C>A" "FIVE_PRIME_INTRON" "Benign" "rs4239794" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 875 1322 0.6619 639 1006 0.6352 506 694 0.7291 849 1008 0.8423 619 978 0.6329 3488 5008 0.696486
489609 "chr21:35839133:A>G" "KCNE1" "NM_001270404:c.-50-17151T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs566425233" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
489610 "chr21:35839140:T>G" "KCNE1" "NM_001270404:c.-50-17158A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs146882579" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489611 "chr21:35839141:C>G" "KCNE1" "NM_001270404:c.-50-17159G>C" "FIVE_PRIME_INTRON" "Benign" "rs4817654" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 875 1322 0.6619 640 1006 0.6362 506 694 0.7291 849 1008 0.8423 619 978 0.6329 3489 5008 0.696685
489612 "chr21:35839188:A>G" "KCNE1" "NM_001270404:c.-50-17206T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs533782426" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489613 "chr21:35839192:G>-" "KCNE1" "NM_001270404:c.-50-17210delC" "FIVE_PRIME_INTRON" "Unknown significance" "rs760320932" "This variant is a VUS because it does not have enough information."
489614 "chr21:35839201:A>G" "KCNE1" "NM_001270404:c.-50-17219T>C" "FIVE_PRIME_INTRON" "Benign" "rs57158552" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 9 1322 0.0068 69 1006 0.0686 47 694 0.0677 136 1008 0.1349 58 978 0.0593 319 5008 0.0636981
489615 "chr21:35839213:T>C" "KCNE1" "NM_001270404:c.-50-17231A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs139482812" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489616 "chr21:35839234:G>A" "KCNE1" "NM_001270404:c.-50-17252C>T" "FIVE_PRIME_INTRON" "Benign" "rs2834487" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 875 1322 0.6619 639 1006 0.6352 506 694 0.7291 849 1008 0.8423 619 978 0.6329 3488 5008 0.696486
489617 "chr21:35839248:G>A" "KCNE1" "NM_001270404:c.-50-17266C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs373735613" "This variant is a VUS because it does not have enough information."
489618 "chr21:35839274:T>C" "KCNE1" "NM_001270404:c.-50-17292A>G" "FIVE_PRIME_INTRON" "Benign" "rs2247804" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 875 1322 0.6619 640 1006 0.6362 506 694 0.7291 849 1008 0.8423 619 978 0.6329 3489 5008 0.696685
489619 "chr21:35839291:G>-" "KCNE1" "NM_001270404:c.-50-17309delC" "FIVE_PRIME_INTRON" "Unknown significance" "rs764794102" "This variant is a VUS because it does not have enough information."
489620 "chr21:35839298:C>T" "KCNE1" "NM_001270404:c.-50-17316G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs373639533" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 1 1006 0.001 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
489621 "chr21:35839299:G>A" "KCNE1" "NM_001270404:c.-50-17317C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs372904800" "This variant is a VUS because it does not have enough information."
489622 "chr21:35839307:A>T" "KCNE1" "NM_001270404:c.-50-17325T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs528767732" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
489623 "chr21:35839317:T>C" "KCNE1" "NM_001270404:c.-50-17335A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs540851511" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
489624 "chr21:35839321:C>T" "KCNE1" "NM_001270404:c.-50-17339G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs189974839" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489625 "chr21:35839399:C>T" "KCNE1" "NM_001270404:c.-50-17417G>A" "FIVE_PRIME_INTRON" "Benign" "rs2247810" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 852 1322 0.6445 639 1006 0.6352 506 694 0.7291 849 1008 0.8423 619 978 0.6329 3465 5008 0.691893
489626 "chr21:35839422:G>T" "KCNE1" "NM_001270404:c.-50-17440C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs550270490" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
489627 "chr21:35839423:T>G" "KCNE1" "NM_001270404:c.-50-17441A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs568565649" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
489628 "chr21:35839431:T>G" "KCNE1" "NM_001270404:c.-50-17449A>C" "FIVE_PRIME_INTRON" "Benign" "rs144203156" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 13 1322 0.0098 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 14 5008 0.00279553
489629 "chr21:35839473:G>A" "KCNE1" "NM_001270404:c.-50-17491C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs574601570" "This variant is a VUS because it does not have enough information."
489630 "chr21:35839484:C>G" "KCNE1" "NM_001270404:c.-50-17502G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs550951600" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 2 978 0.002 2 5008 0.000399361
489631 "chr21:35839500:G>A" "KCNE1" "NM_001270404:c.-50-17518C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs768287285" "This variant is a VUS because it does not have enough information."
489632 "chr21:35839514:C>T" "KCNE1" "NM_001270404:c.-50-17532G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs778817066" "This variant is a VUS because it does not have enough information."
489633 "chr21:35839520:A>C" "KCNE1" "NM_001270404:c.-50-17538T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs151051571" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489634 "chr21:35839529:A>G" "KCNE1" "NM_001270404:c.-50-17547T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs533822117" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 2 978 0.002 2 5008 0.000399361
489635 "chr21:35839574:T>C" "KCNE1" "NM_001270404:c.-50-17592A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs549229470" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489636 "chr21:35839608:T>C" "KCNE1" "NM_001270404:c.-50-17626A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs372476836" "This variant is a VUS because it does not have enough information."
489637 "chr21:35839622:G>C" "KCNE1" "NM_001270404:c.-50-17640C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs567362252" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489638 "chr21:35839623:C>T" "KCNE1" "NM_001270404:c.-50-17641G>A" "FIVE_PRIME_INTRON" "Benign" "rs2247823" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 852 1322 0.6445 639 1006 0.6352 505 694 0.7277 849 1008 0.8423 619 978 0.6329 3464 5008 0.691693
489639 "chr21:35839656:C>G" "KCNE1" "NM_001270404:c.-50-17674G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs771207923" "This variant is a VUS because it does not have enough information."
489640 "chr21:35839773:G>A" "KCNE1" "NM_001270404:c.-50-17791C>T" "FIVE_PRIME_INTRON" "Benign" "rs116273784" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 13 1322 0.0098 0 1006 0 0 694 0 0 1008 0 0 978 0 13 5008 0.00259585
489641 "chr21:35839837:C>T" "KCNE1" "NM_001270404:c.-50-17855G>A" "FIVE_PRIME_INTRON" "Benign" "rs78238889" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 9 1322 0.0068 69 1006 0.0686 47 694 0.0677 136 1008 0.1349 58 978 0.0593 319 5008 0.0636981
489642 "chr21:35839874:C>A" "KCNE1" "NM_001270404:c.-50-17892G>T" "FIVE_PRIME_INTRON" "Benign" "rs140986715" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 10 1322 0.0076 0 1006 0 0 694 0 0 1008 0 0 978 0 10 5008 0.00199681
489643 "chr21:35839884:T>A" "KCNE1" "NM_001270404:c.-50-17902A>T" "FIVE_PRIME_INTRON" "Benign" "rs58295047" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 62 1322 0.0469 1 1006 0.001 1 694 0.0014 0 1008 0 0 978 0 64 5008 0.0127796
489644 "chr21:35839912:G>A" "KCNE1" "NM_001270404:c.-50-17930C>T" "FIVE_PRIME_INTRON" "Benign" "rs149811692" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 3 1322 0.0023 0 1006 0 0 694 0 2 1008 0.002 7 978 0.0072 12 5008 0.00239617
489645 "chr21:35839913:C>A" "KCNE1" "NM_001270404:c.-50-17931G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs78361399" "This variant is a VUS because it does not have enough information."
489646 "chr21:35839917:A>C" "KCNE1" "NM_001270404:c.-50-17935T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs540586059" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489647 "chr21:35839962:A>T" "KCNE1" "NM_001270404:c.-50-17980T>A" "FIVE_PRIME_INTRON" "Benign" "rs111515035" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 23 1322 0.0174 0 1006 0 0 694 0 0 1008 0 0 978 0 23 5008 0.00459265
489648 "chr21:35839963:C>T" "KCNE1" "NM_001270404:c.-50-17981G>A" "FIVE_PRIME_INTRON" "Benign" "rs11701051" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 123 1322 0.093 376 1006 0.3738 189 694 0.2723 94 1008 0.0933 334 978 0.3415 1116 5008 0.222843
489649 "chr21:35839975:C>A" "KCNE1" "NM_001270404:c.-50-17993G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs544398773" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489650 "chr21:35839997:A>C" "KCNE1" "NM_001270404:c.-50-18015T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs562283239" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489651 "chr21:35840033:G>C" "KCNE1" "NM_001270404:c.-50-18051C>G" "FIVE_PRIME_INTRON" "Benign" "rs73900504" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 79 1322 0.0598 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 80 5008 0.0159744
489652 "chr21:35840052:C>T" "KCNE1" "NM_001270404:c.-50-18070G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs550988409" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
489653 "chr21:35840070:G>C" "KCNE1" "NM_001270404:c.-50-18088C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs182057607" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
489654 "chr21:35840093:A>G" "KCNE1" "NM_001270404:c.-50-18111T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs756346760" "This variant is a VUS because it does not have enough information."
489655 "chr21:35840120:T>C" "KCNE1" "NM_001270404:c.-50-18138A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs113272906" "This variant is a VUS because it does not have enough information."
489656 "chr21:35840125:C>G" "KCNE1" "NM_001270404:c.-50-18143G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs564984860" "This variant is a VUS because it does not have enough information."
489657 "chr21:35840201:G>A" "KCNE1" "NM_001270404:c.-50-18219C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs763567907" "This variant is a VUS because it does not have enough information."
489658 "chr21:35840213:C>T" "KCNE1" "NM_001270404:c.-50-18231G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs532489131" "This variant is a VUS because it does not have enough information."
489659 "chr21:35840217:C>T" "KCNE1" "NM_001270404:c.-50-18235G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs527245041" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 1 978 0.001 2 5008 0.000399361
489660 "chr21:35840223:C>T" "KCNE1" "NM_001270404:c.-50-18241G>A" "FIVE_PRIME_INTRON" "Benign" "rs114892475" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 94 1322 0.0711 0 1006 0 5 694 0.0072 0 1008 0 0 978 0 99 5008 0.0197684
489661 "chr21:35840239:G>A" "KCNE1" "NM_001270404:c.-50-18257C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs567550973" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
489662 "chr21:35840247:->A" "KCNE1" "NM_001270404:c.-50-18265_-50-18264insT" "FIVE_PRIME_INTRON" "Benign" "rs35983014" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 385 1322 0.2912 446 1006 0.4433 247 694 0.3559 232 1008 0.2302 399 978 0.408 1709 5008 0.341254
489663 "chr21:35840279:C>T" "KCNE1" "NM_001270404:c.-50-18297G>A" "FIVE_PRIME_INTRON" "Benign" "rs141370591" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 7 1322 0.0053 0 1006 0 0 694 0 0 1008 0 0 978 0 7 5008 0.00139776
489664 "chr21:35840284:C>-" "KCNE1" "NM_001270404:c.-50-18302delG" "FIVE_PRIME_INTRON" "Unknown significance" "rs765825088" "This variant is a VUS because it does not have enough information."
489665 "chr21:35840289:C>T" "KCNE1" "NM_001270404:c.-50-18307G>A" "FIVE_PRIME_INTRON" "Benign" "rs147001459" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1 1322 0.0008 19 1006 0.0189 4 694 0.0058 0 1008 0 2 978 0.002 26 5008 0.00519169
489666 "chr21:35840303:T>A" "KCNE1" "NM_001270404:c.-50-18321A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs116816831" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
489667 "chr21:35840315:C>G" "KCNE1" "NM_001270404:c.-50-18333G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs530333899" "This variant is a VUS because it does not have enough information."
489668 "chr21:35840325:C>T" "KCNE1" "NM_001270404:c.-50-18343G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs539963266" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
489669 "chr21:35840326:G>T" "KCNE1" "NM_001270404:c.-50-18344C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs558198498" "This variant is a VUS because it does not have enough information." 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042
489670 "chr21:35840346:A>C" "KCNE1" "NM_001270404:c.-50-18364T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs573166142" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361
489671 "chr21:35840347:T>G" "KCNE1" "NM_001270404:c.-50-18365A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs368971185" "This variant is a VUS because it does not have enough information."
489672 "chr21:35840362:G>A" "KCNE1" "NM_001270404:c.-50-18380C>T" "FIVE_PRIME_INTRON" "Benign" "rs59624585" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 23 1322 0.0174 0 1006 0 0 694 0 0 1008 0 0 978 0 23 5008 0.00459265
489673 "chr21:35840365:G>A" "KCNE1" "NM_001270404:c.-50-18383C>T" "FIVE_PRIME_INTRON" "Benign" "rs116499972" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 13 1322 0.0098 0 1006 0 0 694 0 0 1008 0 0 978 0 13 5008 0.00259585
489674 "chr21:35840371:G>C" "KCNE1" "NM_001270404:c.-50-18389C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs750101034" "This variant is a VUS because it does not have enough information."
489675 "chr21:35840375:C>T" "KCNE1" "NM_001270404:c.-50-18393G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs186392274" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489676 "chr21:35840398:C>T" "KCNE1" "NM_001270404:c.-50-18416G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs189968335" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
489677 "chr21:35840408:C>T" "KCNE1" "NM_001270404:c.-50-18426G>A" "FIVE_PRIME_INTRON" "Benign" "rs116107358" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 70 1322 0.053 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 71 5008 0.0141773
489678 "chr21:35840417:A>T" "KCNE1" "NM_001270404:c.-50-18435T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs138218174" "This variant is a VUS because it does not have enough information."
489679 "chr21:35840420:C>A" "KCNE1" "NM_001270404:c.-50-18438G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs577786411" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489680 "chr21:35840422:C>G" "KCNE1" "NM_001270404:c.-50-18440G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs182171034" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 3 1006 0.003 1 694 0.0014 0 1008 0 0 978 0 5 5008 0.000998403
489681 "chr21:35840433:C>A" "KCNE1" "NM_001270404:c.-50-18451G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs560150052" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489682 "chr21:35840472:A>G" "KCNE1" "NM_001270404:c.-50-18490T>C" "FIVE_PRIME_INTRON" "Benign" "rs527289133" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 0 1008 0 5 978 0.0051 5 5008 0.000998403
489683 "chr21:35840488:C>A" "KCNE1" "NM_001270404:c.-50-18506G>T" "FIVE_PRIME_INTRON" "Benign" "rs141915862" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 3 1322 0.0023 11 1006 0.0109 6 694 0.0086 0 1008 0 3 978 0.0031 23 5008 0.00459265
489684 "chr21:35840496:C>T" "KCNE1" "NM_001270404:c.-50-18514G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs185772310" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 4 1008 0.004 0 978 0 4 5008 0.000798722
489685 "chr21:35840496:C>A" "KCNE1" "NM_001270404:c.-50-18514G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs185772310" "This variant is a VUS because it does not have enough information."
489686 "chr21:35840505:A>C" "KCNE1" "NM_001270404:c.-50-18523T>G" "FIVE_PRIME_INTRON" "Benign" "rs145757349" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 1 1006 0.001 18 694 0.0259 8 1008 0.0079 0 978 0 27 5008 0.00539137
489687 "chr21:35840516:C>T" "KCNE1" "NM_001270404:c.-50-18534G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs550073629" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489688 "chr21:35840520:G>-" "KCNE1" "NM_001270404:c.-50-18538delC" "FIVE_PRIME_INTRON" "Unknown significance" "rs754877124" "This variant is a VUS because it does not have enough information."
489689 "chr21:35840543:C>T" "KCNE1" "NM_001270404:c.-50-18561G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs191271674" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489690 "chr21:35840570:G>A" "KCNE1" "NM_001270404:c.-50-18588C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs532307067" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489691 "chr21:35840588:T>-" "KCNE1" "NM_001270404:c.-50-18606delA" "FIVE_PRIME_INTRON" "Unknown significance" "rs138966226" "This variant is a VUS because it does not have enough information."
489692 "chr21:35840595:C>T" "KCNE1" "NM_001270404:c.-50-18613G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs551587754" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489693 "chr21:35840619:C>T" "KCNE1" "NM_001270404:c.-50-18637G>A" "FIVE_PRIME_INTRON" "Benign" "rs148206011" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 6 1008 0.006 0 978 0 6 5008 0.00119808
489694 "chr21:35840706:C>T" "KCNE1" "NM_001270404:c.-50-18724G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs778565498" "This variant is a VUS because it does not have enough information."
489695 "chr21:35840710:G>C" "KCNE1" "NM_001270404:c.-50-18728C>G" "FIVE_PRIME_INTRON" "Benign" "rs546853590" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 13 1322 0.0098 0 1006 0 0 694 0 0 1008 0 0 978 0 13 5008 0.00259585
489696 "chr21:35840717:G>C" "KCNE1" "NM_001270404:c.-50-18735C>G" "FIVE_PRIME_INTRON" "Benign" "rs539838664" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 0 1008 0 9 978 0.0092 9 5008 0.00179712
489697 "chr21:35840722:T>C" "KCNE1" "NM_001270404:c.-50-18740A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs567645509" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
489698 "chr21:35840723:C>T" "KCNE1" "NM_001270404:c.-50-18741G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs141190924" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489699 "chr21:35840731:->G" "KCNE1" "NM_001270404:c.-50-18749_-50-18748insC" "FIVE_PRIME_INTRON" "Unknown significance" "rs34873596" "This variant is a VUS because it does not have enough information."
489700 "chr21:35840735:G>A" "KCNE1" "NM_001270404:c.-50-18753C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs75234269" "This variant is a VUS because it does not have enough information." 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403
489701 "chr21:35840748:C>T" "KCNE1" "NM_001270404:c.-50-18766G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs577822136" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
489702 "chr21:35840749:G>A" "KCNE1" "NM_001270404:c.-50-18767C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs374623662" "This variant is a VUS because it does not have enough information."
489703 "chr21:35840775:G>T" "KCNE1" "NM_001270404:c.-50-18793C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs545534310" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
489704 "chr21:35840794:A>T" "KCNE1" "NM_001270404:c.-50-18812T>A" "FIVE_PRIME_INTRON" "Benign" "rs62211544" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 3 1322 0.0023 21 1006 0.0209 4 694 0.0058 0 1008 0 3 978 0.0031 31 5008 0.0061901
489705 "chr21:35840802:C>T" "KCNE1" "NM_001270404:c.-50-18820G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs150753951" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489706 "chr21:35840805:C>A" "KCNE1" "NM_001270404:c.-50-18823G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs374026184" "This variant is a VUS because it does not have enough information."
489707 "chr21:35840814:C>T" "KCNE1" "NM_001270404:c.-50-18832G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs542288406" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489708 "chr21:35840872:T>A" "KCNE1" "NM_001270404:c.-50-18890A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs377010652" "This variant is a VUS because it does not have enough information."
489709 "chr21:35840899:C>T" "KCNE1" "NM_001270404:c.-50-18917G>A" "FIVE_PRIME_INTRON" "Benign" "rs78796611" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1 1322 0.0008 44 1006 0.0437 12 694 0.0173 0 1008 0 65 978 0.0665 122 5008 0.024361
489710 "chr21:35840911:T>G" "KCNE1" "NM_001270404:c.-50-18929A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs531299835" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489711 "chr21:35840929:G>A" "KCNE1" "NM_001270404:c.-50-18947C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs543750855" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489712 "chr21:35840949:T>C" "KCNE1" "NM_001270404:c.-50-18967A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs565130667" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489713 "chr21:35840959:C>T" "KCNE1" "NM_001270404:c.-50-18977G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs769846563" "This variant is a VUS because it does not have enough information."
489714 "chr21:35840961:G>-" "KCNE1" "NM_001270404:c.-50-18979delC" "FIVE_PRIME_INTRON" "Unknown significance" "rs540593473" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 4 978 0.0041 5 5008 0.000998403
489715 "chr21:35841015:G>A" "KCNE1" "NM_001270404:c.-50-19033C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs138873032" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489716 "chr21:35841020:C>G" "KCNE1" "NM_001270404:c.-50-19038G>C" "FIVE_PRIME_INTRON" "Benign" "rs4817655" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 9 1322 0.0068 69 1006 0.0686 48 694 0.0692 133 1008 0.1319 57 978 0.0583 316 5008 0.063099
489717 "chr21:35841022:C>G" "KCNE1" "NM_001270404:c.-50-19040G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs749757908" "This variant is a VUS because it does not have enough information."
489718 "chr21:35841047:A>G" "KCNE1" "NM_001270404:c.-50-19065T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs566886805" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489719 "chr21:35841099:GAGACCTCCCAACAGGGGTCTCCA>-" "KCNE1" "NM_001270404:c.-50-19117_-50-19092delTGGAGACCCCTGTTGGGAGGTCTC" "FIVE_PRIME_INTRON" "Unknown significance" "rs552966868" "This variant is a VUS because it does not have enough information." 0 1322 0 2 1006 0.002 0 694 0 1 1008 0.001 1 978 0.001 4 5008 0.000798722
489720 "chr21:35841109:A>G" "KCNE1" "NM_001270404:c.-50-19127T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs527763197" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
489721 "chr21:35841114:G>C" "KCNE1" "NM_001270404:c.-50-19132C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs769266266" "This variant is a VUS because it does not have enough information."
489722 "chr21:35841172:G>T" "KCNE1" "NM_001270404:c.-50-19190C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs188809345" "This variant is a VUS because it does not have enough information."
489723 "chr21:35841186:T>C" "KCNE1" "NM_001270404:c.-50-19204A>G" "FIVE_PRIME_INTRON" "Benign" "rs4817656" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 892 1322 0.6747 623 1006 0.6193 371 694 0.5346 425 1008 0.4216 606 978 0.6196 2917 5008 0.582468
489724 "chr21:35841210:T>C" "KCNE1" "NM_001270404:c.-50-19228A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs567337036" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489725 "chr21:35841235:C>T" "KCNE1" "NM_001270404:c.-50-19253G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs192868723" "This variant is a VUS because it does not have enough information."
489726 "chr21:35841283:C>A" "KCNE1" "NM_001270404:c.-50-19301G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs537806395" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489727 "chr21:35841293:C>G" "KCNE1" "NM_001270404:c.-50-19311G>C" "FIVE_PRIME_INTRON" "Benign" "rs80108318" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 67 1322 0.0507 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 69 5008 0.013778
489728 "chr21:35841300:G>A" "KCNE1" "NM_001270404:c.-50-19318C>T" "FIVE_PRIME_INTRON" "Benign" "rs9980846" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 456 1322 0.3449 177 1006 0.1759 125 694 0.1801 178 1008 0.1766 154 978 0.1575 1090 5008 0.217652
489729 "chr21:35841301:C>T" "KCNE1" "NM_001270404:c.-50-19319G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs538899122" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 1 694 0.0014 0 1008 0 1 978 0.001 3 5008 0.000599042
489730 "chr21:35841302:G>A" "KCNE1" "NM_001270404:c.-50-19320C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs554323718" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489731 "chr21:35841305:A>C" "KCNE1" "NM_001270404:c.-50-19323T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs572521708" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489732 "chr21:35841328:A>C" "KCNE1" "NM_001270404:c.-50-19346T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs201060582" "This variant is a VUS because it does not have enough information."
489733 "chr21:35841329:->AAAC" "KCNE1" "NM_001270404:c.-50-19347_-50-19346insGTTT" "FIVE_PRIME_INTRON" "Benign" "rs71324305" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 422 1322 0.3192 177 1006 0.1759 125 694 0.1801 179 1008 0.1776 154 978 0.1575 1057 5008 0.211062
489734 "chr21:35841329:->AAACAAAC" "KCNE1" "NM_001270404:c.-50-19347_-50-19346insGTTTGTTT" "FIVE_PRIME_INTRON" "Benign" "rs71324305" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 173 1322 0.1309 1 1006 0.001 7 694 0.0101 24 1008 0.0238 50 978 0.0511 255 5008 0.0509185
489735 "chr21:35841329:->AAACAAACAAAC" "KCNE1" "NM_001270404:c.-50-19347_-50-19346insGTTTGTTTGTTT" "FIVE_PRIME_INTRON" "Benign" "rs71324305" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 124 1322 0.0938 376 1006 0.3738 187 694 0.2695 89 1008 0.0883 331 978 0.3384 1107 5008 0.221046
489736 "chr21:35841330:A>G" "KCNE1" "NM_001270404:c.-50-19348T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs201789967" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 3 1008 0.003 0 978 0 3 5008 0.000599042
489737 "chr21:35841334:->AAAC" "KCNE1" "NM_001270404:c.-50-19352_-50-19351insGTTT" "FIVE_PRIME_INTRON" "Unknown significance" "rs149400558" "This variant is a VUS because it does not have enough information."
489738 "chr21:35841337:->CAAA" "KCNE1" "NM_001270404:c.-50-19355_-50-19354insTTTG" "FIVE_PRIME_INTRON" "Unknown significance" "rs146377818" "This variant is a VUS because it does not have enough information."
489739 "chr21:35841346:G>A" "KCNE1" "NM_001270404:c.-50-19364C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs199965948" "This variant is a VUS because it does not have enough information."
489740 "chr21:35841399:C>T" "KCNE1" "NM_001270404:c.-50-19417G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs142163119" "This variant is a VUS because it does not have enough information." 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 1 978 0.001 6 5008 0.00119808
489741 "chr21:35841450:C>T" "KCNE1" "NM_001270404:c.-50-19468G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs545731689" "This variant is a VUS because it does not have enough information."
489742 "chr21:35841452:C>T" "KCNE1" "NM_001270404:c.-50-19470G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs146379438" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489743 "chr21:35841482:CTC>-" "KCNE1" "NM_001270404:c.-50-19500_-50-19496delGAG" "FIVE_PRIME_INTRON" "Unknown significance" "rs772796991" "This variant is a VUS because it does not have enough information."
489744 "chr21:35841542:T>C" "KCNE1" "NM_001270404:c.-50-19560A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs772947615" "This variant is a VUS because it does not have enough information."
489745 "chr21:35841562:G>A" "KCNE1" "NM_001270404:c.-50-19580C>T" "FIVE_PRIME_INTRON" "Benign" "rs11701906" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 423 1322 0.32 177 1006 0.1759 125 694 0.1801 179 1008 0.1776 154 978 0.1575 1058 5008 0.211262
489746 "chr21:35841589:G>A" "KCNE1" "NM_001270404:c.-50-19607C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs372778210" "This variant is a VUS because it does not have enough information."
489747 "chr21:35841603:G>A" "KCNE1" "NM_001270404:c.-50-19621C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs565219910" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489748 "chr21:35841606:G>A" "KCNE1" "NM_001270404:c.-50-19624C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs577193461" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
489749 "chr21:35841607:C>G" "KCNE1" "NM_001270404:c.-50-19625G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs540896848" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489750 "chr21:35841631:G>C" "KCNE1" "NM_001270404:c.-50-19649C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs559520246" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489751 "chr21:35841636:G>A" "KCNE1" "NM_001270404:c.-50-19654C>T" "FIVE_PRIME_INTRON" "Benign" "rs139761711" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 5 1008 0.005 0 978 0 5 5008 0.000998403
489752 "chr21:35841640:T>C" "KCNE1" "NM_001270404:c.-50-19658A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs549464291" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489753 "chr21:35841669:C>T" "KCNE1" "NM_001270404:c.-50-19687G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs560999103" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489754 "chr21:35841710:G>T" "KCNE1" "NM_001270404:c.-50-19728C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs531638764" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489755 "chr21:35841740:C>A" "KCNE1" "NM_001270404:c.-50-19758G>T" "FIVE_PRIME_INTRON" "Benign" "rs11911509" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 469 1322 0.3548 445 1006 0.4423 245 694 0.353 246 1008 0.244 439 978 0.4489 1844 5008 0.368211
489756 "chr21:35841740:C>G" "KCNE1" "NM_001270404:c.-50-19758G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs11911509" "This variant is a VUS because it does not have enough information."
489757 "chr21:35841753:C>A" "KCNE1" "NM_001270404:c.-50-19771G>T" "FIVE_PRIME_INTRON" "Benign" "rs183376911" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 12 1008 0.0119 0 978 0 12 5008 0.00239617
489758 "chr21:35841792:A>C" "KCNE1" "NM_001270404:c.-50-19810T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs539343003" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489759 "chr21:35841798:A>G" "KCNE1" "NM_001270404:c.-50-19816T>C" "FIVE_PRIME_INTRON" "Benign" "rs113799109" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 79 1322 0.0598 0 1006 0 5 694 0.0072 0 1008 0 0 978 0 84 5008 0.0167732
489760 "chr21:35841820:A>T" "KCNE1" "NM_001270404:c.-50-19838T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs753452724" "This variant is a VUS because it does not have enough information."
489761 "chr21:35841837:C>A" "KCNE1" "NM_001270404:c.-50-19855G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs566273297" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489762 "chr21:35841841:A>G" "KCNE1" "NM_001270404:c.-50-19859T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs754857207" "This variant is a VUS because it does not have enough information."
489763 "chr21:35841849:G>A" "KCNE1" "NM_001270404:c.-50-19867C>T" "FIVE_PRIME_INTRON" "Benign" "rs187635154" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1 1322 0.0008 6 1006 0.006 1 694 0.0014 0 1008 0 0 978 0 8 5008 0.00159744
489764 "chr21:35841873:T>C" "KCNE1" "NM_001270404:c.-50-19891A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs752609932" "This variant is a VUS because it does not have enough information."
489765 "chr21:35841875:G>A" "KCNE1" "NM_001270404:c.-50-19893C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs758140195" "This variant is a VUS because it does not have enough information."
489766 "chr21:35841888:C>T" "KCNE1" "NM_001270404:c.-50-19906G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs377060070" "This variant is a VUS because it does not have enough information."
489767 "chr21:35841911:A>C" "KCNE1" "NM_001270404:c.-50-19929T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs761113283" "This variant is a VUS because it does not have enough information."
489768 "chr21:35841995:G>T" "KCNE1" "NM_001270404:c.-50-20013C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs746062551" "This variant is a VUS because it does not have enough information."
489769 "chr21:35841996:C>G" "KCNE1" "NM_001270404:c.-50-20014G>C" "FIVE_PRIME_INTRON" "Benign" "rs111468554" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 43 1322 0.0325 0 1006 0 3 694 0.0043 0 1008 0 0 978 0 46 5008 0.0091853
489770 "chr21:35842020:G>A" "KCNE1" "NM_001270404:c.-50-20038C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs563009577" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
489771 "chr21:35842045:A>T" "KCNE1" "NM_001270404:c.-50-20063T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs755199377" "This variant is a VUS because it does not have enough information."
489772 "chr21:35842048:T>C" "KCNE1" "NM_001270404:c.-50-20066A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs537077788" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
489773 "chr21:35842104:T>A" "KCNE1" "NM_001270404:c.-50-20122A>T" "FIVE_PRIME_INTRON" "Benign" "rs76148249" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 24 1322 0.0182 0 1006 0 0 694 0 0 1008 0 0 978 0 24 5008 0.00479233
489774 "chr21:35842111:C>G" "KCNE1" "NM_001270404:c.-50-20129G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs756397300" "This variant is a VUS because it does not have enough information."
489775 "chr21:35842114:G>A" "KCNE1" "NM_001270404:c.-50-20132C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs191336860" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489776 "chr21:35842165:A>G" "KCNE1" "NM_001270404:c.-50-20183T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs779987503" "This variant is a VUS because it does not have enough information."
489777 "chr21:35842166:A>G" "KCNE1" "NM_001270404:c.-50-20184T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs370873279" "This variant is a VUS because it does not have enough information."
489778 "chr21:35842169:A>G" "KCNE1" "NM_001270404:c.-50-20187T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs541332962" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489779 "chr21:35842184:T>C" "KCNE1" "NM_001270404:c.-50-20202A>G" "FIVE_PRIME_INTRON" "Benign" "rs75121659" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 104 1322 0.0787 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 106 5008 0.0211661
489780 "chr21:35842187:G>T" "KCNE1" "NM_001270404:c.-50-20205C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs574577402" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489781 "chr21:35842213:C>T" "KCNE1" "NM_001270404:c.-50-20231G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs768620672" "This variant is a VUS because it does not have enough information."
489782 "chr21:35842214:G>A" "KCNE1" "NM_001270404:c.-50-20232C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs541618964" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489783 "chr21:35842260:T>C" "KCNE1" "NM_001270404:c.-50-20278A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs561084036" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489784 "chr21:35842266:C>T" "KCNE1" "NM_001270404:c.-50-20284G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs748684400" "This variant is a VUS because it does not have enough information."
489785 "chr21:35842267:A>G" "KCNE1" "NM_001270404:c.-50-20285T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs772542510" "This variant is a VUS because it does not have enough information."
489786 "chr21:35842285:A>G" "KCNE1" "NM_001270404:c.-50-20303T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs773751762" "This variant is a VUS because it does not have enough information."
489787 "chr21:35842288:->G" "KCNE1" "NM_001270404:c.-50-20306_-50-20305insC" "FIVE_PRIME_INTRON" "Unknown significance" "rs780252531" "This variant is a VUS because it does not have enough information."
489788 "chr21:35842307:G>A" "KCNE1" "NM_001270404:c.-50-20325C>T" "FIVE_PRIME_INTRON" "Benign" "rs112596899" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 21 1322 0.0159 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 23 5008 0.00459265
489789 "chr21:35842307:G>C" "KCNE1" "NM_001270404:c.-50-20325C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs112596899" "This variant is a VUS because it does not have enough information."
489790 "chr21:35842327:T>C" "KCNE1" "NM_001270404:c.-50-20345A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs530188353" "This variant is a VUS because it does not have enough information."
489791 "chr21:35842328:G>A" "KCNE1" "NM_001270404:c.-50-20346C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs766113026" "This variant is a VUS because it does not have enough information."
489792 "chr21:35842331:G>C" "KCNE1" "NM_001270404:c.-50-20349C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs776153578" "This variant is a VUS because it does not have enough information."
489793 "chr21:35842345:G>A" "KCNE1" "NM_001270404:c.-50-20363C>T" "FIVE_PRIME_INTRON" "Benign" "rs12483550" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 78 1322 0.059 2 1006 0.002 130 694 0.1873 486 1008 0.4821 23 978 0.0235 719 5008 0.14357
489794 "chr21:35842345:G>C" "KCNE1" "NM_001270404:c.-50-20363C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs12483550" "This variant is a VUS because it does not have enough information."
489795 "chr21:35842369:T>C" "KCNE1" "NM_001270404:c.-50-20387A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs564955241" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489796 "chr21:35842394:C>T" "KCNE1" "NM_001270404:c.-50-20412G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs532364457" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489797 "chr21:35842398:C>T" "KCNE1" "NM_001270404:c.-50-20416G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs548073049" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489798 "chr21:35842409:G>A" "KCNE1" "NM_001270404:c.-50-20427C>T" "FIVE_PRIME_INTRON" "Benign" "rs73365324" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 61 1322 0.0461 1 1006 0.001 1 694 0.0014 0 1008 0 0 978 0 63 5008 0.0125799
489799 "chr21:35842417:C>T" "KCNE1" "NM_001270404:c.-50-20435G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs758375311" "This variant is a VUS because it does not have enough information."
489800 "chr21:35842451:C>G" "KCNE1" "NM_001270404:c.-50-20469G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs183485806" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489801 "chr21:35842460:G>A" "KCNE1" "NM_001270404:c.-50-20478C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs548784992" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 3 978 0.0031 3 5008 0.000599042
489802 "chr21:35842466:T>C" "KCNE1" "NM_001270404:c.-50-20484A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs569794626" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
489803 "chr21:35842473:T>C" "KCNE1" "NM_001270404:c.-50-20491A>G" "FIVE_PRIME_INTRON" "Benign" "rs189581644" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 4 694 0.0058 6 1008 0.006 0 978 0 10 5008 0.00199681
489804 "chr21:35842598:A>G" "KCNE1" "NM_001270404:c.-50-20616T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs757019360" "This variant is a VUS because it does not have enough information."
489805 "chr21:35842636:G>C" "KCNE1" "NM_001270404:c.-50-20654C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs374223221" "This variant is a VUS because it does not have enough information."
489806 "chr21:35842757:C>T" "KCNE1" "NM_001270404:c.-50-20775G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs545843020" "This variant is a VUS because it does not have enough information."
489807 "chr21:35842772:AAT>-" "KCNE1" "NM_001270404:c.-50-20790_-50-20786delATT" "FIVE_PRIME_INTRON" "Unknown significance" "rs539517642" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 1 1006 0.001 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042
489808 "chr21:35842813:G>A" "KCNE1" "NM_001270404:c.-50-20831C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs558650553" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489809 "chr21:35842825:T>C" "KCNE1" "NM_001270404:c.-50-20843A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs576781101" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
489810 "chr21:35842836:A>G" "KCNE1" "NM_001270404:c.-50-20854T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs534274804" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 2 978 0.002 2 5008 0.000399361
489811 "chr21:35842868:C>T" "KCNE1" "NM_001270404:c.-50-20886G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs780253396" "This variant is a VUS because it does not have enough information."
489812 "chr21:35842892:C>G" "KCNE1" "NM_001270404:c.-50-20910G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs148725255" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489813 "chr21:35842916:A>G" "KCNE1" "NM_001270404:c.-50-20934T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs193005958" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
489814 "chr21:35842945:A>G" "KCNE1" "NM_001270404:c.-50-20963T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs368722760" "This variant is a VUS because it does not have enough information."
489815 "chr21:35842954:C>G" "KCNE1" "NM_001270404:c.-50-20972G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs541653696" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489816 "chr21:35842964:A>G" "KCNE1" "NM_001270404:c.-50-20982T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs184717998" "This variant is a VUS because it does not have enough information." 6 1322 0.0045 0 1006 0 0 694 0 0 1008 0 0 978 0 6 5008 0.00119808
489817 "chr21:35842965:T>C" "KCNE1" "NM_001270404:c.-50-20983A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs575063132" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489818 "chr21:35843022:A>G" "KCNE1" "NM_001270404:c.-50-21040T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs78960367" "This variant is a VUS because it does not have enough information."
489819 "chr21:35843026:T>G" "KCNE1" "NM_001270404:c.-50-21044A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs772631106" "This variant is a VUS because it does not have enough information."
489820 "chr21:35843031:T>C" "KCNE1" "NM_001270404:c.-50-21049A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs543521557" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489821 "chr21:35843033:G>A" "KCNE1" "NM_001270404:c.-50-21051C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs754035740" "This variant is a VUS because it does not have enough information."
489822 "chr21:35843039:C>T" "KCNE1" "NM_001270404:c.-50-21057G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs552934109" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489823 "chr21:35843057:G>C" "KCNE1" "NM_001270404:c.-50-21075C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs190378893" "This variant is a VUS because it does not have enough information."
489824 "chr21:35843075:G>C" "KCNE1" "NM_001270404:c.-50-21093C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs778904701" "This variant is a VUS because it does not have enough information."
489825 "chr21:35843086:G>C" "KCNE1" "NM_001270404:c.-50-21104C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs532586270" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489826 "chr21:35843125:G>A" "KCNE1" "NM_001270404:c.-50-21143C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs541058295" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
489827 "chr21:35843127:A>G" "KCNE1" "NM_001270404:c.-50-21145T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs560029448" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
489828 "chr21:35843135:C>T" "KCNE1" "NM_001270404:c.-50-21153G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs553470226" "This variant is a VUS because it does not have enough information."
489829 "chr21:35843199:C>T" "KCNE1" "NM_001270404:c.-50-21217G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs772771769" "This variant is a VUS because it does not have enough information."
489830 "chr21:35843237:C>T" "KCNE1" "NM_001270404:c.-50-21255G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs530395838" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489831 "chr21:35843280:->A" "KCNE1" "NM_001270404:c.-50-21298_-50-21297insT" "FIVE_PRIME_INTRON" "Unknown significance" "rs753478182" "This variant is a VUS because it does not have enough information."
489832 "chr21:35843406:G>T" "KCNE1" "NM_001270404:c.-50-21424C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs778267784" "This variant is a VUS because it does not have enough information."
489833 "chr21:35843409:A>G" "KCNE1" "NM_001270404:c.-50-21427T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs113493878" "This variant is a VUS because it does not have enough information."
489834 "chr21:35843417:A>C" "KCNE1" "NM_001270404:c.-50-21435T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs55739929" "This variant is a VUS because it does not have enough information."
489835 "chr21:35843465:A>T" "KCNE1" "NM_001270404:c.-50-21483T>A" "FIVE_PRIME_INTRON" "Benign" "rs142330513" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 7 1322 0.0053 0 1006 0 0 694 0 0 1008 0 0 978 0 7 5008 0.00139776
489836 "chr21:35843483:A>G" "KCNE1" "NM_001270404:c.-50-21501T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs570278257" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 2 5008 0.000399361
489837 "chr21:35843497:T>C" "KCNE1" "NM_001270404:c.-50-21515A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs747318907" "This variant is a VUS because it does not have enough information."
489838 "chr21:35843515:A>G" "KCNE1" "NM_001270404:c.-50-21533T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs116275029" "This variant is a VUS because it does not have enough information."
489839 "chr21:35843604:T>C" "KCNE1" "NM_001270404:c.-50-21622A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs747381424" "This variant is a VUS because it does not have enough information."
489840 "chr21:35843632:A>G" "KCNE1" "NM_001270404:c.-50-21650T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs531085322" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489841 "chr21:35843650:A>T" "KCNE1" "NM_001270404:c.-50-21668T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs151278786" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 1 1006 0.001 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
489842 "chr21:35843653:T>G" "KCNE1" "NM_001270404:c.-50-21671A>C" "FIVE_PRIME_INTRON" "Benign" "rs141305848" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 2 1322 0.0015 8 1006 0.008 7 694 0.0101 0 1008 0 1 978 0.001 18 5008 0.00359425
489843 "chr21:35843687:T>A" "KCNE1" "NM_001270404:c.-50-21705A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs759160602" "This variant is a VUS because it does not have enough information."
489844 "chr21:35843712:G>A" "KCNE1" "NM_001270404:c.-50-21730C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs759189839" "This variant is a VUS because it does not have enough information."
489845 "chr21:35843716:->T" "KCNE1" "NM_001270404:c.-50-21734_-50-21733insA" "FIVE_PRIME_INTRON" "Benign" "rs199870814" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 35 1322 0.0265 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 37 5008 0.00738818
489846 "chr21:35843722:T>C" "KCNE1" "NM_001270404:c.-50-21740A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs534651522" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489847 "chr21:35843734:A>G" "KCNE1" "NM_001270404:c.-50-21752T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs552676023" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489848 "chr21:35843766:A>G" "KCNE1" "NM_001270404:c.-50-21784T>C" "FIVE_PRIME_INTRON" "Benign" "rs568023781" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 0 1008 0 8 978 0.0082 8 5008 0.00159744
489849 "chr21:35843779:G>A" "KCNE1" "NM_001270404:c.-50-21797C>T" "FIVE_PRIME_INTRON" "Benign" "rs145238297" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 10 1322 0.0076 0 1006 0 0 694 0 0 1008 0 0 978 0 10 5008 0.00199681
489850 "chr21:35843789:C>T" "KCNE1" "NM_001270404:c.-50-21807G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs372605466" "This variant is a VUS because it does not have enough information."
489851 "chr21:35843790:G>A" "KCNE1" "NM_001270404:c.-50-21808C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs181535687" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489852 "chr21:35843820:G>T" "KCNE1" "NM_001270404:c.-50-21838C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs769317193" "This variant is a VUS because it does not have enough information."
489853 "chr21:35843825:T>A" "KCNE1" "NM_001270404:c.-50-21843A>T" "FIVE_PRIME_INTRON" "Benign" "rs575102725" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 0 1008 0 6 978 0.0061 6 5008 0.00119808
489854 "chr21:35843829:T>-" "KCNE1" "NM_001270404:c.-50-21847delA" "FIVE_PRIME_INTRON" "Unknown significance" "rs769273304" "This variant is a VUS because it does not have enough information."
489855 "chr21:35843840:T>G" "KCNE1" "NM_001270404:c.-50-21858A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs764992117" "This variant is a VUS because it does not have enough information."
489856 "chr21:35843865:T>C" "KCNE1" "NM_001270404:c.-50-21883A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs545590797" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
489857 "chr21:35843911:G>C" "KCNE1" "NM_001270404:c.-50-21929C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs186510978" "This variant is a VUS because it does not have enough information."
489858 "chr21:35843921:C>T" "KCNE1" "NM_001270404:c.-50-21939G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs375675618" "This variant is a VUS because it does not have enough information."
489859 "chr21:35843993:G>C" "KCNE1" "NM_001270404:c.-50-22011C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs559051160" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 2 978 0.002 2 5008 0.000399361
489860 "chr21:35844029:T>C" "KCNE1" "NM_001270404:c.-50-22047A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs763964977" "This variant is a VUS because it does not have enough information."
489861 "chr21:35844058:G>A" "KCNE1" "NM_001270404:c.-50-22076C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs751500043" "This variant is a VUS because it does not have enough information."
489862 "chr21:35844066:A>-" "KCNE1" "NM_001270404:c.-50-22084delT" "FIVE_PRIME_INTRON" "Benign" "rs59277894" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 158 1322 0.1195 1 1006 0.001 3 694 0.0043 2 1008 0.002 7 978 0.0072 171 5008 0.0341454
489863 "chr21:35844105:T>C" "KCNE1" "NM_001270404:c.-50-22123A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs549567790" "This variant is a VUS because it does not have enough information."
489864 "chr21:35844124:C>G" "KCNE1" "NM_001270404:c.-50-22142G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs577251551" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489865 "chr21:35844140:T>C" "KCNE1" "NM_001270404:c.-50-22158A>G" "FIVE_PRIME_INTRON" "Benign" "rs147630729" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 5 1006 0.005 3 694 0.0043 22 1008 0.0218 0 978 0 30 5008 0.00599042
489866 "chr21:35844159:AA>-" "KCNE1" "NM_001270404:c.-50-22177_-50-22174delTT" "FIVE_PRIME_INTRON" "Unknown significance" "rs777120682" "This variant is a VUS because it does not have enough information."
489867 "chr21:35844161:G>A" "KCNE1" "NM_001270404:c.-50-22179C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs372188784" "This variant is a VUS because it does not have enough information."
489868 "chr21:35844174:A>G" "KCNE1" "NM_001270404:c.-50-22192T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs559509293" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 1 694 0.0014 0 1008 0 0 978 0 2 5008 0.000399361
489869 "chr21:35844237:A>C" "KCNE1" "NM_001270404:c.-50-22255T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs564540410" "This variant is a VUS because it does not have enough information."
489870 "chr21:35844265:T>C" "KCNE1" "NM_001270404:c.-50-22283A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs530082520" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 2 5008 0.000399361
489871 "chr21:35844314:A>G" "KCNE1" "NM_001270404:c.-50-22332T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs542548097" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489872 "chr21:35844323:C>A" "KCNE1" "NM_001270404:c.-50-22341G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs563925048" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489873 "chr21:35844368:G>A" "KCNE1" "NM_001270404:c.-50-22386C>T" "FIVE_PRIME_INTRON" "Benign" "rs77271698" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 2 1322 0.0015 15 1006 0.0149 4 694 0.0058 0 1008 0 1 978 0.001 22 5008 0.00439297
489874 "chr21:35844376:G>T" "KCNE1" "NM_001270404:c.-50-22394C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs9979117" "This variant is a VUS because it does not have enough information."
489875 "chr21:35844513:G>T" "KCNE1" "NM_001270404:c.-50-22531C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs150174329" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 3 1008 0.003 0 978 0 3 5008 0.000599042
489876 "chr21:35844565:A>C" "KCNE1" "NM_001270404:c.-50-22583T>G" "FIVE_PRIME_INTRON" "Benign" "rs73365326" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 62 1322 0.0469 1 1006 0.001 1 694 0.0014 0 1008 0 0 978 0 64 5008 0.0127796
489877 "chr21:35844588:A>G" "KCNE1" "NM_001270404:c.-50-22606T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs528151045" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
489878 "chr21:35844598:T>C" "KCNE1" "NM_001270404:c.-50-22616A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs573264301" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 2 978 0.002 2 5008 0.000399361
489879 "chr21:35844644:T>A" "KCNE1" "NM_001270404:c.-50-22662A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs567974070" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489880 "chr21:35844729:T>C" "KCNE1" "NM_001270404:c.-50-22747A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs189342414" "This variant is a VUS because it does not have enough information." 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403
489881 "chr21:35844770:A>G" "KCNE1" "NM_001270404:c.-50-22788T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs556884645" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489882 "chr21:35844800:T>C" "KCNE1" "NM_001270404:c.-50-22818A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs568802910" "This variant is a VUS because it does not have enough information." 0 1322 0 2 1006 0.002 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
489883 "chr21:35844894:G>A" "KCNE1" "NM_001270404:c.-50-22912C>T" "FIVE_PRIME_INTRON" "Benign" "rs112655174" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 61 1322 0.0461 2 1006 0.002 1 694 0.0014 0 1008 0 2 978 0.002 66 5008 0.0131789
489884 "chr21:35844900:T>C" "KCNE1" "NM_001270404:c.-50-22918A>G" "FIVE_PRIME_INTRON" "Benign" "rs2834488" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 9 1322 0.0068 68 1006 0.0676 48 694 0.0692 133 1008 0.1319 57 978 0.0583 315 5008 0.0628994
489885 "chr21:35844912:T>C" "KCNE1" "NM_001270404:c.-50-22930A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs572964016" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489886 "chr21:35844999:G>T" "KCNE1" "NM_001270404:c.-50-23017C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs534823305" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489887 "chr21:35845004:A>T" "KCNE1" "NM_001270404:c.-50-23022T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs148827836" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489888 "chr21:35845020:A>G" "KCNE1" "NM_001270404:c.-50-23038T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs758564198" "This variant is a VUS because it does not have enough information."
489889 "chr21:35845048:T>C" "KCNE1" "NM_001270404:c.-50-23066A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs574887893" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489890 "chr21:35845079:A>T" "KCNE1" "NM_001270404:c.-50-23097T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs143482191" "This variant is a VUS because it does not have enough information." 0 1322 0 3 1006 0.003 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042
489891 "chr21:35845135:C>T" "KCNE1" "NM_001270404:c.-50-23153G>A" "FIVE_PRIME_INTRON" "Benign" "rs77447953" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 246 1322 0.1861 0 1006 0 9 694 0.013 0 1008 0 0 978 0 255 5008 0.0509185
489892 "chr21:35845147:A>T" "KCNE1" "NM_001270404:c.-50-23165T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs575991512" "This variant is a VUS because it does not have enough information." 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042
489893 "chr21:35845191:C>T" "KCNE1" "NM_001270404:c.-50-23209G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs747542169" "This variant is a VUS because it does not have enough information."
489894 "chr21:35845252:T>C" "KCNE1" "NM_001270404:c.-50-23270A>G" "FIVE_PRIME_INTRON" "Benign" "rs180918215" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 19 1322 0.0144 0 1006 0 0 694 0 0 1008 0 0 978 0 19 5008 0.00379393
489895 "chr21:35845267:G>A" "KCNE1" "NM_001270404:c.-50-23285C>T" "FIVE_PRIME_INTRON" "Benign" "rs186261930" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 19 1322 0.0144 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 20 5008 0.00399361
489896 "chr21:35845271:T>A" "KCNE1" "NM_001270404:c.-50-23289A>T" "FIVE_PRIME_INTRON" "Benign" "rs111381758" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 42 1322 0.0318 0 1006 0 3 694 0.0043 0 1008 0 0 978 0 45 5008 0.00898562
489897 "chr21:35845308:T>G" "KCNE1" "NM_001270404:c.-50-23326A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs137937251" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 3 1008 0.003 0 978 0 3 5008 0.000599042
489898 "chr21:35845319:C>T" "KCNE1" "NM_001270404:c.-50-23337G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs371449367" "This variant is a VUS because it does not have enough information."
489899 "chr21:35845366:T>C" "KCNE1" "NM_001270404:c.-50-23384A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs367711061" "This variant is a VUS because it does not have enough information."
489900 "chr21:35845387:A>T" "KCNE1" "NM_001270404:c.-50-23405T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs561446563" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489901 "chr21:35845415:A>G" "KCNE1" "NM_001270404:c.-50-23433T>C" "FIVE_PRIME_INTRON" "Benign" "rs142099403" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 13 1008 0.0129 0 978 0 13 5008 0.00259585
489902 "chr21:35845448:C>G" "KCNE1" "NM_001270404:c.-50-23466G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs550145582" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
489903 "chr21:35845464:A>G" "KCNE1" "NM_001270404:c.-50-23482T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs745533271" "This variant is a VUS because it does not have enough information."
489904 "chr21:35845471:G>A" "KCNE1" "NM_001270404:c.-50-23489C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs796266885" "This variant is a VUS because it does not have enough information."
489905 "chr21:35845484:C>T" "KCNE1" "NM_001270404:c.-50-23502G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs568842012" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489906 "chr21:35845485:G>C" "KCNE1" "NM_001270404:c.-50-23503C>G" "FIVE_PRIME_INTRON" "Benign" "rs62211545" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 127 1322 0.0961 376 1006 0.3738 188 694 0.2709 93 1008 0.0923 334 978 0.3415 1118 5008 0.223243
489907 "chr21:35845509:A>G" "KCNE1" "NM_001270404:c.-50-23527T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs369847224" "This variant is a VUS because it does not have enough information."
489908 "chr21:35845521:G>A" "KCNE1" "NM_001270404:c.-50-23539C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs775139897" "This variant is a VUS because it does not have enough information."
489909 "chr21:35845607:C>T" "KCNE1" "NM_001270404:c.-50-23625G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs762385666" "This variant is a VUS because it does not have enough information."
489910 "chr21:35845638:T>C" "KCNE1" "NM_001270404:c.-50-23656A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs550565159" "This variant is a VUS because it does not have enough information."
489911 "chr21:35845645:A>G" "KCNE1" "NM_001270404:c.-50-23663T>C" "FIVE_PRIME_INTRON" "Benign" "rs8128386" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 348 1322 0.2632 377 1006 0.3748 193 694 0.2781 95 1008 0.0942 339 978 0.3466 1352 5008 0.269968
489912 "chr21:35845646:A>G" "KCNE1" "NM_001270404:c.-50-23664T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs566556009" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489913 "chr21:35845668:T>C" "KCNE1" "NM_001270404:c.-50-23686A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs533940499" "This variant is a VUS because it does not have enough information." 6 1322 0.0045 0 1006 0 0 694 0 0 1008 0 0 978 0 6 5008 0.00119808
489914 "chr21:35845697:A>T" "KCNE1" "NM_001270404:c.-50-23715T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs774222320" "This variant is a VUS because it does not have enough information."
489915 "chr21:35845704:C>T" "KCNE1" "NM_001270404:c.-50-23722G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs755180943" "This variant is a VUS because it does not have enough information."
489916 "chr21:35845714:T>C" "KCNE1" "NM_001270404:c.-50-23732A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs556332012" "This variant is a VUS because it does not have enough information."
489917 "chr21:35845725:C>T" "KCNE1" "NM_001270404:c.-50-23743G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs190733599" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489918 "chr21:35845771:G>A" "KCNE1" "NM_001270404:c.-50-23789C>T" "FIVE_PRIME_INTRON" "Benign" "rs4817657" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 348 1322 0.2632 445 1006 0.4423 241 694 0.3473 228 1008 0.2262 396 978 0.4049 1658 5008 0.33107
489919 "chr21:35845775:G>C" "KCNE1" "NM_001270404:c.-50-23793C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs183398379" "This variant is a VUS because it does not have enough information." 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042
489920 "chr21:35845778:A>C" "KCNE1" "NM_001270404:c.-50-23796T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs186255655" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 1 694 0.0014 0 1008 0 0 978 0 2 5008 0.000399361
489921 "chr21:35845788:A>G" "KCNE1" "NM_001270404:c.-50-23806T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs575679631" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489922 "chr21:35845808:G>C" "KCNE1" "NM_001270404:c.-50-23826C>G" "FIVE_PRIME_INTRON" "Benign" "rs190580898" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 8 1322 0.0061 0 1006 0 0 694 0 0 1008 0 0 978 0 8 5008 0.00159744
489923 "chr21:35845823:C>T" "KCNE1" "NM_001270404:c.-50-23841G>A" "FIVE_PRIME_INTRON" "Benign" "rs4816487" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1240 1322 0.938 724 1006 0.7197 573 694 0.8256 1005 1008 0.997 751 978 0.7679 4293 5008 0.857228
489924 "chr21:35845841:A>G" "KCNE1" "NM_001270404:c.-50-23859T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs750251282" "This variant is a VUS because it does not have enough information."
489925 "chr21:35845863:A>C" "KCNE1" "NM_001270404:c.-50-23881T>G" "FIVE_PRIME_INTRON" "Benign" "rs28802678" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 115 1322 0.087 1 1006 0.001 4 694 0.0058 38 1008 0.0377 39 978 0.0399 197 5008 0.0393371
489926 "chr21:35845865:C>T" "KCNE1" "NM_001270404:c.-50-23883G>A" "FIVE_PRIME_INTRON" "Benign" "rs80338475" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 80 1322 0.0605 0 1006 0 3 694 0.0043 0 1008 0 0 978 0 83 5008 0.0165735
489927 "chr21:35845874:C>T" "KCNE1" "NM_001270404:c.-50-23892G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs146360663" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
489928 "chr21:35845889:C>A" "KCNE1" "NM_001270404:c.-50-23907G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs777934296" "This variant is a VUS because it does not have enough information."
489929 "chr21:35845923:A>G" "KCNE1" "NM_001270404:c.-50-23941T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs553193588" "This variant is a VUS because it does not have enough information."
489930 "chr21:35845956:C>A" "KCNE1" "NM_001270404:c.-50-23974G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs765495572" "This variant is a VUS because it does not have enough information."
489931 "chr21:35845986:G>A" "KCNE1" "NM_001270404:c.-50-24004C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs528935914" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 2 978 0.002 2 5008 0.000399361
489932 "chr21:35846004:C>A" "KCNE1" "NM_001270404:c.-50-24022G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs182759324" "This variant is a VUS because it does not have enough information."
489933 "chr21:35846014:G>C" "KCNE1" "NM_001270404:c.-50-24032C>G" "FIVE_PRIME_INTRON" "Benign" "rs138452877" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 10 1322 0.0076 0 1006 0 0 694 0 0 1008 0 0 978 0 10 5008 0.00199681
489934 "chr21:35846021:C>T" "KCNE1" "NM_001270404:c.-50-24039G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs752971340" "This variant is a VUS because it does not have enough information."
489935 "chr21:35846031:C>A" "KCNE1" "NM_001270404:c.-50-24049G>T" "FIVE_PRIME_INTRON" "Benign" "rs4816488" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 347 1322 0.2625 445 1006 0.4423 241 694 0.3473 228 1008 0.2262 396 978 0.4049 1657 5008 0.330871
489936 "chr21:35846034:G>A" "KCNE1" "NM_001270404:c.-50-24052C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs532898850" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
489937 "chr21:35846122:A>C" "KCNE1" "NM_001270404:c.-50-24140T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs764321452" "This variant is a VUS because it does not have enough information."
489938 "chr21:35846164:A>G" "KCNE1" "NM_001270404:c.-50-24182T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs572698260" "This variant is a VUS because it does not have enough information."
489939 "chr21:35846199:T>G" "KCNE1" "NM_001270404:c.-50-24217A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs370639126" "This variant is a VUS because it does not have enough information."
489940 "chr21:35846217:T>C" "KCNE1" "NM_001270404:c.-50-24235A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs551390206" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489941 "chr21:35846257:A>C" "KCNE1" "NM_001270404:c.-50-24275T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs71329069" "This variant is a VUS because it does not have enough information."
489942 "chr21:35846260:A>G" "KCNE1" "NM_001270404:c.-50-24278T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs546482927" "This variant is a VUS because it does not have enough information."
489943 "chr21:35846294:G>A" "KCNE1" "NM_001270404:c.-50-24312C>T" "FIVE_PRIME_INTRON" "Benign" "rs566755550" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 8 1322 0.0061 0 1006 0 0 694 0 0 1008 0 0 978 0 8 5008 0.00159744
489944 "chr21:35846318:G>A" "KCNE1" "NM_001270404:c.-50-24336C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs757772949" "This variant is a VUS because it does not have enough information."
489945 "chr21:35846333:T>G" "KCNE1" "NM_001270404:c.-50-24351A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs533785022" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489946 "chr21:35846344:T>C" "KCNE1" "NM_001270404:c.-50-24362A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs549180834" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489947 "chr21:35846358:A>G" "KCNE1" "NM_001270404:c.-50-24376T>C" "FIVE_PRIME_INTRON" "Benign" "rs57119453" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 9 1322 0.0068 68 1006 0.0676 48 694 0.0692 133 1008 0.1319 57 978 0.0583 315 5008 0.0628994
489948 "chr21:35846375:->A" "KCNE1" "NM_001270404:c.-50-24393_-50-24392insT" "FIVE_PRIME_INTRON" "Benign" "rs564077293" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 5 1006 0.005 3 694 0.0043 1 1008 0.001 0 978 0 9 5008 0.00179712
489949 "chr21:35846384:AT>-" "KCNE1" "NM_001270404:c.-50-24402_-50-24399delAT" "FIVE_PRIME_INTRON" "Unknown significance" "rs746289148" "This variant is a VUS because it does not have enough information."
489950 "chr21:35846458:C>A" "KCNE1" "NM_001270404:c.-50-24476G>T" "FIVE_PRIME_INTRON" "Benign" "rs78350699" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 80 1322 0.0605 0 1006 0 3 694 0.0043 0 1008 0 0 978 0 83 5008 0.0165735
489951 "chr21:35846474:A>G" "KCNE1" "NM_001270404:c.-50-24492T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs376868656" "This variant is a VUS because it does not have enough information."
489952 "chr21:35846494:C>T" "KCNE1" "NM_001270404:c.-50-24512G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs557452897" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 3 1008 0.003 0 978 0 3 5008 0.000599042
489953 "chr21:35846542:T>G" "KCNE1" "NM_001270404:c.-50-24560A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs775043050" "This variant is a VUS because it does not have enough information."
489954 "chr21:35846567:G>T" "KCNE1" "NM_001270404:c.-50-24585C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs756478661" "This variant is a VUS because it does not have enough information."
489955 "chr21:35846604:G>A" "KCNE1" "NM_001270404:c.-50-24622C>T" "FIVE_PRIME_INTRON" "Benign" "rs57518667" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 9 1322 0.0068 68 1006 0.0676 48 694 0.0692 133 1008 0.1319 57 978 0.0583 315 5008 0.0628994
489956 "chr21:35846634:G>A" "KCNE1" "NM_001270404:c.-50-24652C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs187792095" "This variant is a VUS because it does not have enough information."
489957 "chr21:35846638:T>C" "KCNE1" "NM_001270404:c.-50-24656A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs190707179" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489958 "chr21:35846676:T>C" "KCNE1" "NM_001270404:c.-50-24694A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs768128454" "This variant is a VUS because it does not have enough information."
489959 "chr21:35846703:A>G" "KCNE1" "NM_001270404:c.-50-24721T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs768011816" "This variant is a VUS because it does not have enough information."
489960 "chr21:35846768:A>G" "KCNE1" "NM_001270404:c.-50-24786T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs773887914" "This variant is a VUS because it does not have enough information."
489961 "chr21:35846927:G>A" "KCNE1" "NM_001270404:c.-50-24945C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs558210173" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489962 "chr21:35846944:T>G" "KCNE1" "NM_001270404:c.-50-24962A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs376088549" "This variant is a VUS because it does not have enough information."
489963 "chr21:35846945:T>C" "KCNE1" "NM_001270404:c.-50-24963A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs561568606" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 3 694 0.0043 0 1008 0 0 978 0 4 5008 0.000798722
489964 "chr21:35846965:C>T" "KCNE1" "NM_001270404:c.-50-24983G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs540498540" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
489965 "chr21:35847039:C>T" "KCNE1" "NM_001270404:c.-50-25057G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs183227054" "This variant is a VUS because it does not have enough information."
489966 "chr21:35847100:T>C" "KCNE1" "NM_001270404:c.-50-25118A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs771960667" "This variant is a VUS because it does not have enough information."
489967 "chr21:35847108:->ATT" "KCNE1" "NM_001270404:c.-50-25126_-50-25125insAAT" "FIVE_PRIME_INTRON" "Unknown significance" "rs772760723" "This variant is a VUS because it does not have enough information."
489968 "chr21:35847142:C>A" "KCNE1" "NM_001270404:c.-50-25160G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs555563851" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489969 "chr21:35847160:G>C" "KCNE1" "NM_001270404:c.-50-25178C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs143040791" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 3 1008 0.003 0 978 0 3 5008 0.000599042
489970 "chr21:35847179:G>T" "KCNE1" "NM_001270404:c.-50-25197C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs535892518" "This variant is a VUS because it does not have enough information."
489971 "chr21:35847189:A>G" "KCNE1" "NM_001270404:c.-50-25207T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs760318211" "This variant is a VUS because it does not have enough information."
489972 "chr21:35847214:G>A" "KCNE1" "NM_001270404:c.-50-25232C>T" "FIVE_PRIME_INTRON" "Benign" "rs4817658" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 339 1322 0.2564 444 1006 0.4414 240 694 0.3458 227 1008 0.2252 398 978 0.407 1648 5008 0.329073
489973 "chr21:35847239:C>A" "KCNE1" "NM_001270404:c.-50-25257G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs775834951" "This variant is a VUS because it does not have enough information."
489974 "chr21:35847271:C>A" "KCNE1" "NM_001270404:c.-50-25289G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs763307274" "This variant is a VUS because it does not have enough information."
489975 "chr21:35847312:C>A" "KCNE1" "NM_001270404:c.-50-25330G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs547116531" "This variant is a VUS because it does not have enough information."
489976 "chr21:35847377:A>G" "KCNE1" "NM_001270404:c.-50-25395T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs371583360" "This variant is a VUS because it does not have enough information."
489977 "chr21:35847380:A>G" "KCNE1" "NM_001270404:c.-50-25398T>C" "FIVE_PRIME_INTRON" "Benign" "rs115190043" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 24 1322 0.0182 0 1006 0 0 694 0 0 1008 0 0 978 0 24 5008 0.00479233
489978 "chr21:35847384:C>A" "KCNE1" "NM_001270404:c.-50-25402G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs540473000" "This variant is a VUS because it does not have enough information."
489979 "chr21:35847420:T>C" "KCNE1" "NM_001270404:c.-50-25438A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs750217200" "This variant is a VUS because it does not have enough information."
489980 "chr21:35847461:A>T" "KCNE1" "NM_001270404:c.-50-25479T>A" "FIVE_PRIME_INTRON" "Benign" "rs150702163" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1 1322 0.0008 12 1006 0.0119 6 694 0.0086 0 1008 0 3 978 0.0031 22 5008 0.00439297
489981 "chr21:35847476:A>G" "KCNE1" "NM_001270404:c.-50-25494T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs544979446" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489982 "chr21:35847549:T>C" "KCNE1" "NM_001270404:c.-50-25567A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs757374553" "This variant is a VUS because it does not have enough information."
489983 "chr21:35847564:GACAT>-" "KCNE1" "NM_001270404:c.-50-25582_-50-25576delATGTC" "FIVE_PRIME_INTRON" "Unknown significance" "rs146480235" "This variant is a VUS because it does not have enough information."
489984 "chr21:35847572:A>G" "KCNE1" "NM_001270404:c.-50-25590T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs767849922" "This variant is a VUS because it does not have enough information."
489985 "chr21:35847582:C>A" "KCNE1" "NM_001270404:c.-50-25600G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs560219611" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361
489986 "chr21:35847585:T>C" "KCNE1" "NM_001270404:c.-50-25603A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs370912103" "This variant is a VUS because it does not have enough information."
489987 "chr21:35847616:C>T" "KCNE1" "NM_001270404:c.-50-25634G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs796351928" "This variant is a VUS because it does not have enough information."
489988 "chr21:35847697:A>G" "KCNE1" "NM_001270404:c.-50-25715T>C" "FIVE_PRIME_INTRON" "Benign" "rs11910430" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 27 1322 0.0204 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 28 5008 0.00559105
489989 "chr21:35847736:C>A" "KCNE1" "NM_001270404:c.-50-25754G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs188030121" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
489990 "chr21:35847741:G>T" "KCNE1" "NM_001270404:c.-50-25759C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs192261746" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489991 "chr21:35847753:T>C" "KCNE1" "NM_001270404:c.-50-25771A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs531488749" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489992 "chr21:35847797:T>C" "KCNE1" "NM_001270404:c.-50-25815A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs551144059" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489993 "chr21:35847801:C>G" "KCNE1" "NM_001270404:c.-50-25819G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs569327218" "This variant is a VUS because it does not have enough information." 4 1322 0.003 0 1006 0 0 694 0 0 1008 0 0 978 0 4 5008 0.000798722
489994 "chr21:35847815:C>T" "KCNE1" "NM_001270404:c.-50-25833G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs539484505" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
489995 "chr21:35847822:A>G" "KCNE1" "NM_001270404:c.-50-25840T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs139675326" "This variant is a VUS because it does not have enough information." 4 1322 0.003 0 1006 0 0 694 0 0 1008 0 0 978 0 4 5008 0.000798722
489996 "chr21:35847829:C>G" "KCNE1" "NM_001270404:c.-50-25847G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs566726512" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
489997 "chr21:35847830:G>A" "KCNE1" "NM_001270404:c.-50-25848C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs117007139" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 2 1006 0.002 0 694 0 0 1008 0 1 978 0.001 4 5008 0.000798722
489998 "chr21:35847839:A>T" "KCNE1" "NM_001270404:c.-50-25857T>A" "FIVE_PRIME_INTRON" "Benign" "rs551339542" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 5 1006 0.005 0 694 0 0 1008 0 2 978 0.002 7 5008 0.00139776
489999 "chr21:35847887:T>C" "KCNE1" "NM_001270404:c.-50-25905A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs185001133" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
490000 "chr21:35847889:G>-" "KCNE1" "NM_001270404:c.-50-25907delC" "FIVE_PRIME_INTRON" "Unknown significance" "rs765911376" "This variant is a VUS because it does not have enough information."
490001 "chr21:35847889:G>C" "KCNE1" "NM_001270404:c.-50-25907C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs544398774" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490002 "chr21:35847890:A>T" "KCNE1" "NM_001270404:c.-50-25908T>A" "FIVE_PRIME_INTRON" "Benign" "rs75877036" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 10 1322 0.0076 67 1006 0.0666 44 694 0.0634 146 1008 0.1448 56 978 0.0573 323 5008 0.0644968
490003 "chr21:35847891:T>A" "KCNE1" "NM_001270404:c.-50-25909A>T" "FIVE_PRIME_INTRON" "Benign" "rs7279865" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 97 1322 0.0734 1 1006 0.001 4 694 0.0058 0 1008 0 0 978 0 102 5008 0.0203674
490004 "chr21:35847916:T>C" "KCNE1" "NM_001270404:c.-50-25934A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs754689303" "This variant is a VUS because it does not have enough information."
490005 "chr21:35847929:C>A" "KCNE1" "NM_001270404:c.-50-25947G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs544703139" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
490006 "chr21:35847933:->A" "KCNE1" "NM_001270404:c.-50-25951_-50-25950insT" "FIVE_PRIME_INTRON" "Unknown significance" "rs373495534" "This variant is a VUS because it does not have enough information."
490007 "chr21:35847942:A>G" "KCNE1" "NM_001270404:c.-50-25960T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs554822312" "This variant is a VUS because it does not have enough information."
490008 "chr21:35847967:T>C" "KCNE1" "NM_001270404:c.-50-25985A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs544469370" "This variant is a VUS because it does not have enough information."
490009 "chr21:35847968:T>C" "KCNE1" "NM_001270404:c.-50-25986A>G" "FIVE_PRIME_INTRON" "Benign" "rs112951383" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 43 1322 0.0325 0 1006 0 3 694 0.0043 0 1008 0 0 978 0 46 5008 0.0091853
490010 "chr21:35848003:T>A" "KCNE1" "NM_001270404:c.-50-26021A>T" "FIVE_PRIME_INTRON" "Benign" "rs149777981" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1 1322 0.0008 10 1006 0.0099 9 694 0.013 0 1008 0 0 978 0 20 5008 0.00399361
490011 "chr21:35848019:T>A" "KCNE1" "NM_001270404:c.-50-26037A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs555292195" "This variant is a VUS because it does not have enough information."
490012 "chr21:35848048:A>C" "KCNE1" "NM_001270404:c.-50-26066T>G" "FIVE_PRIME_INTRON" "Benign" "rs187880375" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 6 1006 0.006 0 694 0 0 1008 0 0 978 0 6 5008 0.00119808
490013 "chr21:35848050:A>G" "KCNE1" "NM_001270404:c.-50-26068T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs771615671" "This variant is a VUS because it does not have enough information."
490014 "chr21:35848051:C>T" "KCNE1" "NM_001270404:c.-50-26069G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs561164973" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490015 "chr21:35848053:A>G" "KCNE1" "NM_001270404:c.-50-26071T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs531579203" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 2 978 0.002 2 5008 0.000399361
490016 "chr21:35848135:A>G" "KCNE1" "NM_001270404:c.-50-26153T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs549987809" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 2 978 0.002 2 5008 0.000399361
490017 "chr21:35848137:G>-" "KCNE1" "NM_001270404:c.-50-26155delC" "FIVE_PRIME_INTRON" "Unknown significance" "rs201999671" "This variant is a VUS because it does not have enough information."
490018 "chr21:35848140:A>-" "KCNE1" "NM_001270404:c.-50-26158delT" "FIVE_PRIME_INTRON" "Unknown significance" "rs34172849" "This variant is a VUS because it does not have enough information."
490019 "chr21:35848140:GA>-" "KCNE1" "NM_001270404:c.-50-26158_-50-26155delTC" "FIVE_PRIME_INTRON" "Unknown significance" "rs386818151" "This variant is a VUS because it does not have enough information."
490020 "chr21:35848140:A>T" "KCNE1" "NM_001270404:c.-50-26158T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs79373074" "This variant is a VUS because it does not have enough information."
490021 "chr21:35848197:A>C" "KCNE1" "NM_001270404:c.-50-26215T>G" "FIVE_PRIME_INTRON" "Benign" "rs79015575" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 27 1322 0.0204 0 1006 0 0 694 0 0 1008 0 0 978 0 27 5008 0.00539137
490022 "chr21:35848270:C>T" "KCNE1" "NM_001270404:c.-50-26288G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs746992285" "This variant is a VUS because it does not have enough information."
490023 "chr21:35848344:A>G" "KCNE1" "NM_001270404:c.-50-26362T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs184389790" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490024 "chr21:35848384:C>T" "KCNE1" "NM_001270404:c.-50-26402G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs551551456" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490025 "chr21:35848395:C>T" "KCNE1" "NM_001270404:c.-50-26413G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs566868316" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490026 "chr21:35848415:T>A" "KCNE1" "NM_001270404:c.-50-26433A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs533886454" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490027 "chr21:35848424:A>T" "KCNE1" "NM_001270404:c.-50-26442T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs549312159" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490028 "chr21:35848432:A>G" "KCNE1" "NM_001270404:c.-50-26450T>C" "FIVE_PRIME_INTRON" "Benign" "rs144708192" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 9 1006 0.0089 6 694 0.0086 0 1008 0 0 978 0 15 5008 0.00299521
490029 "chr21:35848474:A>G" "KCNE1" "NM_001270404:c.-50-26492T>C" "FIVE_PRIME_INTRON" "Benign" "rs139989376" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1 1322 0.0008 9 1006 0.0089 6 694 0.0086 0 1008 0 3 978 0.0031 19 5008 0.00379393
490030 "chr21:35848499:A>G" "KCNE1" "NM_001270404:c.-50-26517T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs763255726" "This variant is a VUS because it does not have enough information."
490031 "chr21:35848544:C>T" "KCNE1" "NM_001270404:c.-50-26562G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs371694812" "This variant is a VUS because it does not have enough information." 4 1322 0.003 0 1006 0 0 694 0 0 1008 0 0 978 0 4 5008 0.000798722
490032 "chr21:35848548:A>G" "KCNE1" "NM_001270404:c.-50-26566T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs764356540" "This variant is a VUS because it does not have enough information."
490033 "chr21:35848593:C>T" "KCNE1" "NM_001270404:c.-50-26611G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs554321959" "This variant is a VUS because it does not have enough information."
490034 "chr21:35848599:T>C" "KCNE1" "NM_001270404:c.-50-26617A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs572629590" "This variant is a VUS because it does not have enough information."
490035 "chr21:35848615:T>C" "KCNE1" "NM_001270404:c.-50-26633A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs770330668" "This variant is a VUS because it does not have enough information."
490036 "chr21:35848647:C>G" "KCNE1" "NM_001270404:c.-50-26665G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs578088137" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490037 "chr21:35848683:T>C" "KCNE1" "NM_001270404:c.-50-26701A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs538741129" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490038 "chr21:35848710:A>G" "KCNE1" "NM_001270404:c.-50-26728T>C" "FIVE_PRIME_INTRON" "Benign" "rs71329070" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 96 1322 0.0726 194 1006 0.1928 114 694 0.1643 143 1008 0.1419 120 978 0.1227 667 5008 0.133187
490039 "chr21:35848727:T>C" "KCNE1" "NM_001270404:c.-50-26745A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs572120573" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490040 "chr21:35848731:C>T" "KCNE1" "NM_001270404:c.-50-26749G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs761762693" "This variant is a VUS because it does not have enough information."
490041 "chr21:35848799:C>T" "KCNE1" "NM_001270404:c.-50-26817G>A" "FIVE_PRIME_INTRON" "Benign" "rs542637151" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 6 1008 0.006 1 978 0.001 7 5008 0.00139776
490042 "chr21:35848800:T>A" "KCNE1" "NM_001270404:c.-50-26818A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs371945439" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490043 "chr21:35848812:C>G" "KCNE1" "NM_001270404:c.-50-26830G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs189490450" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490044 "chr21:35848822:A>G" "KCNE1" "NM_001270404:c.-50-26840T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs543712298" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
490045 "chr21:35848826:A>C" "KCNE1" "NM_001270404:c.-50-26844T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs565106038" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490046 "chr21:35848851:T>C" "KCNE1" "NM_001270404:c.-50-26869A>G" "FIVE_PRIME_INTRON" "Benign" "rs116009594" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 13 1322 0.0098 0 1006 0 0 694 0 0 1008 0 0 978 0 13 5008 0.00259585
490047 "chr21:35848861:C>T" "KCNE1" "NM_001270404:c.-50-26879G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs182044838" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
490048 "chr21:35848910:T>A" "KCNE1" "NM_001270404:c.-50-26928A>T" "FIVE_PRIME_INTRON" "Benign" "rs9983904" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 382 1322 0.289 436 1006 0.4334 227 694 0.3271 231 1008 0.2292 374 978 0.3824 1650 5008 0.329473
490049 "chr21:35848910:T>C" "KCNE1" "NM_001270404:c.-50-26928A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs9983904" "This variant is a VUS because it does not have enough information."
490050 "chr21:35848940:A>C" "KCNE1" "NM_001270404:c.-50-26958T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs527720273" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361
490051 "chr21:35848952:C>T" "KCNE1" "NM_001270404:c.-50-26970G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs768368824" "This variant is a VUS because it does not have enough information."
490052 "chr21:35848972:G>A" "KCNE1" "NM_001270404:c.-50-26990C>T" "FIVE_PRIME_INTRON" "Benign" "rs117974640" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 10 1322 0.0076 64 1006 0.0636 44 694 0.0634 131 1008 0.13 58 978 0.0593 307 5008 0.0613019
490053 "chr21:35849031:C>T" "KCNE1" "NM_001270404:c.-50-27049G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs567643488" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490054 "chr21:35849047:T>A" "KCNE1" "NM_001270404:c.-50-27065A>T" "FIVE_PRIME_INTRON" "Benign" "rs9984007" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 382 1322 0.289 436 1006 0.4334 227 694 0.3271 231 1008 0.2292 375 978 0.3834 1651 5008 0.329673
490055 "chr21:35849072:T>G" "KCNE1" "NM_001270404:c.-50-27090A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs754257605" "This variant is a VUS because it does not have enough information."
490056 "chr21:35849076:C>T" "KCNE1" "NM_001270404:c.-50-27094G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs147609180" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 3 1008 0.003 0 978 0 4 5008 0.000798722
490057 "chr21:35849088:G>A" "KCNE1" "NM_001270404:c.-50-27106C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs375348599" "This variant is a VUS because it does not have enough information."
490058 "chr21:35849118:CTCA>-" "KCNE1" "NM_001270404:c.-50-27136_-50-27131delTGAG" "FIVE_PRIME_INTRON" "Unknown significance" "rs767348618" "This variant is a VUS because it does not have enough information."
490059 "chr21:35849130:T>C" "KCNE1" "NM_001270404:c.-50-27148A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs571819559" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490060 "chr21:35849179:C>T" "KCNE1" "NM_001270404:c.-50-27197G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs538856929" "This variant is a VUS because it does not have enough information." 4 1322 0.003 0 1006 0 0 694 0 0 1008 0 0 978 0 4 5008 0.000798722
490061 "chr21:35849203:G>-" "KCNE1" "NM_001270404:c.-50-27221delC" "FIVE_PRIME_INTRON" "Benign" "rs201152328" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 39 1322 0.0295 0 1006 0 0 694 0 20 1008 0.0198 22 978 0.0225 81 5008 0.0161741
490062 "chr21:35849203:->G" "KCNE1" "NM_001270404:c.-50-27221_-50-27220insC" "FIVE_PRIME_INTRON" "Unknown significance" "rs71324307" "This variant is a VUS because it does not have enough information."
490063 "chr21:35849204:->GGA" "KCNE1" "NM_001270404:c.-50-27222_-50-27221insTCC" "FIVE_PRIME_INTRON" "Unknown significance" "rs752626879" "This variant is a VUS because it does not have enough information."
490064 "chr21:35849204:G>C" "KCNE1" "NM_001270404:c.-50-27222C>G" "FIVE_PRIME_INTRON" "Benign" "rs56079127" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 63 1322 0.0477 0 1006 0 0 694 0 0 1008 0 0 978 0 63 5008 0.0125799
490065 "chr21:35849205:G>C" "KCNE1" "NM_001270404:c.-50-27223C>G" "FIVE_PRIME_INTRON" "Benign" "rs9983688" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 15 1006 0.0149 7 694 0.0101 0 1008 0 8 978 0.0082 30 5008 0.00599042
490066 "chr21:35849205:G>T" "KCNE1" "NM_001270404:c.-50-27223C>A" "FIVE_PRIME_INTRON" "Benign" "rs9983688" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 48 1322 0.0363 8 1006 0.008 6 694 0.0086 0 1008 0 21 978 0.0215 83 5008 0.0165735
490067 "chr21:35849209:G>T" "KCNE1" "NM_001270404:c.-50-27227C>A" "FIVE_PRIME_INTRON" "Benign" "rs554626669" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 19 1322 0.0144 0 1006 0 0 694 0 0 1008 0 0 978 0 19 5008 0.00379393
490068 "chr21:35849218:C>A" "KCNE1" "NM_001270404:c.-50-27236G>T" "FIVE_PRIME_INTRON" "Benign" "rs9983530" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 59 1322 0.0446 1 1006 0.001 1 694 0.0014 0 1008 0 0 978 0 61 5008 0.0121805
490069 "chr21:35849230:T>A" "KCNE1" "NM_001270404:c.-50-27248A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs543711542" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490070 "chr21:35849262:G>A" "KCNE1" "NM_001270404:c.-50-27280C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs564986809" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 4 978 0.0041 4 5008 0.000798722
490071 "chr21:35849267:C>A" "KCNE1" "NM_001270404:c.-50-27285G>T" "FIVE_PRIME_INTRON" "Benign" "rs577012684" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 8 1322 0.0061 0 1006 0 0 694 0 0 1008 0 0 978 0 8 5008 0.00159744
490072 "chr21:35849276:C>G" "KCNE1" "NM_001270404:c.-50-27294G>C" "FIVE_PRIME_INTRON" "Benign" "rs140043629" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 49 1322 0.0371 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 50 5008 0.00998403
490073 "chr21:35849290:T>C" "KCNE1" "NM_001270404:c.-50-27308A>G" "FIVE_PRIME_INTRON" "Benign" "rs150298940" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1 1322 0.0008 0 1006 0 99 694 0.1427 6 1008 0.006 0 978 0 106 5008 0.0211661
490074 "chr21:35849305:C>G" "KCNE1" "NM_001270404:c.-50-27323G>C" "FIVE_PRIME_INTRON" "Benign" "rs185483722" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 6 1006 0.006 2 694 0.0029 0 1008 0 0 978 0 8 5008 0.00159744
490075 "chr21:35849306:G>A" "KCNE1" "NM_001270404:c.-50-27324C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs547050487" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490076 "chr21:35849314:C>T" "KCNE1" "NM_001270404:c.-50-27332G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs560959898" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490077 "chr21:35849321:C>T" "KCNE1" "NM_001270404:c.-50-27339G>A" "FIVE_PRIME_INTRON" "Benign" "rs113000351" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 10 1322 0.0076 64 1006 0.0636 44 694 0.0634 131 1008 0.13 58 978 0.0593 307 5008 0.0613019
490078 "chr21:35849348:->AT" "KCNE1" "NM_001270404:c.-50-27366_-50-27365insAT" "FIVE_PRIME_INTRON" "Benign" "rs138980567" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 160 1322 0.121 366 1006 0.3638 179 694 0.2579 97 1008 0.0962 312 978 0.319 1114 5008 0.222444
490079 "chr21:35849348:->ATAT" "KCNE1" "NM_001270404:c.-50-27366_-50-27365insATAT" "FIVE_PRIME_INTRON" "Unknown significance" "rs138980567" "This variant is a VUS because it does not have enough information."
490080 "chr21:35849405:C>T" "KCNE1" "NM_001270404:c.-50-27423G>A" "FIVE_PRIME_INTRON" "Benign" "rs79371057" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 10 1322 0.0076 64 1006 0.0636 44 694 0.0634 131 1008 0.13 58 978 0.0593 307 5008 0.0613019
490081 "chr21:35849409:A>G" "KCNE1" "NM_001270404:c.-50-27427T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs376336749" "This variant is a VUS because it does not have enough information."
490082 "chr21:35849423:G>T" "KCNE1" "NM_001270404:c.-50-27441C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs746941018" "This variant is a VUS because it does not have enough information."
490083 "chr21:35849492:G>A" "KCNE1" "NM_001270404:c.-50-27510C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs140902969" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490084 "chr21:35849530:T>C" "KCNE1" "NM_001270404:c.-50-27548A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs532776930" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490085 "chr21:35849585:G>A" "KCNE1" "NM_001270404:c.-50-27603C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs569787030" "This variant is a VUS because it does not have enough information."
490086 "chr21:35849619:A>C" "KCNE1" "NM_001270404:c.-50-27637T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs144704848" "This variant is a VUS because it does not have enough information." 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042
490087 "chr21:35849687:A>C" "KCNE1" "NM_001270404:c.-50-27705T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs760633150" "This variant is a VUS because it does not have enough information."
490088 "chr21:35849702:A>G" "KCNE1" "NM_001270404:c.-50-27720T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs138403503" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490089 "chr21:35849706:C>T" "KCNE1" "NM_001270404:c.-50-27724G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs536368764" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 4 978 0.0041 4 5008 0.000798722
490090 "chr21:35849734:G>A" "KCNE1" "NM_001270404:c.-50-27752C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs369307646" "This variant is a VUS because it does not have enough information."
490091 "chr21:35849750:G>A" "KCNE1" "NM_001270404:c.-50-27768C>T" "FIVE_PRIME_INTRON" "Benign" "rs57872552" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 10 1322 0.0076 64 1006 0.0636 44 694 0.0634 132 1008 0.131 58 978 0.0593 308 5008 0.0615016
490092 "chr21:35849833:T>A" "KCNE1" "NM_001270404:c.-50-27851A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs189561848" "This variant is a VUS because it does not have enough information."
490093 "chr21:35849867:G>A" "KCNE1" "NM_001270404:c.-50-27885C>T" "FIVE_PRIME_INTRON" "Benign" "rs73365337" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 203 1322 0.1536 0 1006 0 9 694 0.013 19 1008 0.0188 39 978 0.0399 270 5008 0.0539137
490094 "chr21:35849903:G>A" "KCNE1" "NM_001270404:c.-50-27921C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs180755038" "This variant is a VUS because it does not have enough information."
490095 "chr21:35849920:G>A" "KCNE1" "NM_001270404:c.-50-27938C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs536638712" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
490096 "chr21:35849934:T>A" "KCNE1" "NM_001270404:c.-50-27952A>T" "FIVE_PRIME_INTRON" "Benign" "rs55755452" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 4 1322 0.003 41 1006 0.0408 13 694 0.0187 0 1008 0 63 978 0.0644 121 5008 0.0241613
490097 "chr21:35849942:G>A" "KCNE1" "NM_001270404:c.-50-27960C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs535857119" "This variant is a VUS because it does not have enough information."
490098 "chr21:35849965:G>A" "KCNE1" "NM_001270404:c.-50-27983C>T" "FIVE_PRIME_INTRON" "Benign" "rs115488300" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 13 1322 0.0098 0 1006 0 0 694 0 0 1008 0 0 978 0 13 5008 0.00259585
490099 "chr21:35849968:->TGGG" "KCNE1" "NM_001270404:c.-50-27986_-50-27985insCCCA" "FIVE_PRIME_INTRON" "Unknown significance" "rs148002500" "This variant is a VUS because it does not have enough information."
490100 "chr21:35849998:C>G" "KCNE1" "NM_001270404:c.-50-28016G>C" "FIVE_PRIME_INTRON" "Benign" "rs77398442" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 133 1322 0.1006 64 1006 0.0636 52 694 0.0749 131 1008 0.13 57 978 0.0583 437 5008 0.0872604
490101 "chr21:35850068:A>G" "KCNE1" "NM_001270404:c.-50-28086T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs572565801" "This variant is a VUS because it does not have enough information."
490102 "chr21:35850113:A>G" "KCNE1" "NM_001270404:c.-50-28131T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs555557449" "This variant is a VUS because it does not have enough information."
490103 "chr21:35850175:A>G" "KCNE1" "NM_001270404:c.-50-28193T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs552767306" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490104 "chr21:35850187:C>T" "KCNE1" "NM_001270404:c.-50-28205G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs539588819" "This variant is a VUS because it does not have enough information."
490105 "chr21:35850188:G>A" "KCNE1" "NM_001270404:c.-50-28206C>T" "FIVE_PRIME_INTRON" "Benign" "rs115931904" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 39 1322 0.0295 0 1006 0 0 694 0 0 1008 0 0 978 0 39 5008 0.00778754
490106 "chr21:35850200:G>A" "KCNE1" "NM_001270404:c.-50-28218C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs762141517" "This variant is a VUS because it does not have enough information."
490107 "chr21:35850219:T>C" "KCNE1" "NM_001270404:c.-50-28237A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs772009696" "This variant is a VUS because it does not have enough information."
490108 "chr21:35850234:C>T" "KCNE1" "NM_001270404:c.-50-28252G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs149619320" "This variant is a VUS because it does not have enough information." 6 1322 0.0045 0 1006 0 0 694 0 0 1008 0 0 978 0 6 5008 0.00119808
490109 "chr21:35850263:T>G" "KCNE1" "NM_001270404:c.-50-28281A>C" "FIVE_PRIME_INTRON" "Benign" "rs560999174" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1 1322 0.0008 2 1006 0.002 0 694 0 5 1008 0.005 0 978 0 8 5008 0.00159744
490110 "chr21:35850302:A>G" "KCNE1" "NM_001270404:c.-50-28320T>C" "FIVE_PRIME_INTRON" "Benign" "rs6517232" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 917 1322 0.6936 648 1006 0.6441 373 694 0.5375 393 1008 0.3899 534 978 0.546 2865 5008 0.572085
490111 "chr21:35850304:G>A" "KCNE1" "NM_001270404:c.-50-28322C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs543439650" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490112 "chr21:35850309:T>C" "KCNE1" "NM_001270404:c.-50-28327A>G" "FIVE_PRIME_INTRON" "Benign" "rs113961785" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 39 1322 0.0295 0 1006 0 3 694 0.0043 0 1008 0 0 978 0 42 5008 0.00838658
490113 "chr21:35850320:G>C" "KCNE1" "NM_001270404:c.-50-28338C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs532719837" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490114 "chr21:35850354:C>G" "KCNE1" "NM_001270404:c.-50-28372G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs186617294" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490115 "chr21:35850374:G>T" "KCNE1" "NM_001270404:c.-50-28392C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs189941911" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
490116 "chr21:35850438:C>T" "KCNE1" "NM_001270404:c.-50-28456G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs181562234" "This variant is a VUS because it does not have enough information."
490117 "chr21:35850439:G>A" "KCNE1" "NM_001270404:c.-50-28457C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs186046711" "This variant is a VUS because it does not have enough information." 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042
490118 "chr21:35850463:A>T" "KCNE1" "NM_001270404:c.-50-28481T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs757451360" "This variant is a VUS because it does not have enough information."
490119 "chr21:35850469:C>T" "KCNE1" "NM_001270404:c.-50-28487G>A" "FIVE_PRIME_INTRON" "Benign" "rs116754784" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 25 1322 0.0189 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 27 5008 0.00539137
490120 "chr21:35850472:T>A" "KCNE1" "NM_001270404:c.-50-28490A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs544064281" "This variant is a VUS because it does not have enough information."
490121 "chr21:35850475:A>C" "KCNE1" "NM_001270404:c.-50-28493T>G" "FIVE_PRIME_INTRON" "Benign" "rs73900506" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 63 1322 0.0477 0 1006 0 0 694 0 0 1008 0 0 978 0 63 5008 0.0125799
490122 "chr21:35850501:A>C" "KCNE1" "NM_001270404:c.-50-28519T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs555796629" "This variant is a VUS because it does not have enough information."
490123 "chr21:35850513:A>G" "KCNE1" "NM_001270404:c.-50-28531T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs537082670" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490124 "chr21:35850522:T>A" "KCNE1" "NM_001270404:c.-50-28540A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs558245131" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 2 978 0.002 2 5008 0.000399361
490125 "chr21:35850575:G>T" "KCNE1" "NM_001270404:c.-50-28593C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs759854271" "This variant is a VUS because it does not have enough information."
490126 "chr21:35850581:C>T" "KCNE1" "NM_001270404:c.-50-28599G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs570399631" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
490127 "chr21:35850585:C>G" "KCNE1" "NM_001270404:c.-50-28603G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs534626006" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490128 "chr21:35850590:A>G" "KCNE1" "NM_001270404:c.-50-28608T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs552805829" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490129 "chr21:35850620:A>C" "KCNE1" "NM_001270404:c.-50-28638T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs765656205" "This variant is a VUS because it does not have enough information."
490130 "chr21:35850622:T>C" "KCNE1" "NM_001270404:c.-50-28640A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs574293478" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490131 "chr21:35850627:G>A" "KCNE1" "NM_001270404:c.-50-28645C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs190463890" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
490132 "chr21:35850630:G>A" "KCNE1" "NM_001270404:c.-50-28648C>T" "FIVE_PRIME_INTRON" "Benign" "rs112514387" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 38 1322 0.0287 0 1006 0 3 694 0.0043 0 1008 0 0 978 0 41 5008 0.0081869
490133 "chr21:35850681:G>T" "KCNE1" "NM_001270404:c.-50-28699C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs576439676" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490134 "chr21:35850709:A>C" "KCNE1" "NM_001270404:c.-50-28727T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs543873100" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 2 978 0.002 2 5008 0.000399361
490135 "chr21:35850712:C>T" "KCNE1" "NM_001270404:c.-50-28730G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs565153887" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
490136 "chr21:35850713:G>A" "KCNE1" "NM_001270404:c.-50-28731C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs143380102" "This variant is a VUS because it does not have enough information." 6 1322 0.0045 0 1006 0 0 694 0 0 1008 0 0 978 0 6 5008 0.00119808
490137 "chr21:35850739:C>A" "KCNE1" "NM_001270404:c.-50-28757G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs541750042" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490138 "chr21:35850745:G>A" "KCNE1" "NM_001270404:c.-50-28763C>T" "FIVE_PRIME_INTRON" "Benign" "rs148377940" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 22 1322 0.0166 0 1006 0 3 694 0.0043 0 1008 0 0 978 0 25 5008 0.00499201
490139 "chr21:35850755:A>G" "KCNE1" "NM_001270404:c.-50-28773T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs758137402" "This variant is a VUS because it does not have enough information."
490140 "chr21:35850767:G>A" "KCNE1" "NM_001270404:c.-50-28785C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs530356319" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490141 "chr21:35850832:T>G" "KCNE1" "NM_001270404:c.-50-28850A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs184189065" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361
490142 "chr21:35850880:G>A" "KCNE1" "NM_001270404:c.-50-28898C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs563424950" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
490143 "chr21:35850895:A>G" "KCNE1" "NM_001270404:c.-50-28913T>C" "FIVE_PRIME_INTRON" "Benign" "rs188691568" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 7 1322 0.0053 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 8 5008 0.00159744
490144 "chr21:35850913:C>G" "KCNE1" "NM_001270404:c.-50-28931G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs777136057" "This variant is a VUS because it does not have enough information."
490145 "chr21:35850928:A>G" "KCNE1" "NM_001270404:c.-50-28946T>C" "FIVE_PRIME_INTRON" "Benign" "rs191124490" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 6 1006 0.006 1 694 0.0014 0 1008 0 0 978 0 7 5008 0.00139776
490146 "chr21:35850934:A>C" "KCNE1" "NM_001270404:c.-50-28952T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs570359797" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490147 "chr21:35850946:G>A" "KCNE1" "NM_001270404:c.-50-28964C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs141393595" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 3 1008 0.003 0 978 0 3 5008 0.000599042
490148 "chr21:35850953:C>T" "KCNE1" "NM_001270404:c.-50-28971G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs545430232" "This variant is a VUS because it does not have enough information."
490149 "chr21:35850999:A>C" "KCNE1" "NM_001270404:c.-50-29017T>G" "FIVE_PRIME_INTRON" "Benign" "rs150822417" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 8 1006 0.008 6 694 0.0086 0 1008 0 0 978 0 14 5008 0.00279553
490150 "chr21:35851041:C>G" "KCNE1" "NM_001270404:c.-50-29059G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs11702634" "This variant is a VUS because it does not have enough information."
490151 "chr21:35851085:T>C" "KCNE1" "NM_001270404:c.-50-29103A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs781238284" "This variant is a VUS because it does not have enough information."
490152 "chr21:35851105:G>A" "KCNE1" "NM_001270404:c.-50-29123C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs568000817" "This variant is a VUS because it does not have enough information." 6 1322 0.0045 0 1006 0 0 694 0 0 1008 0 0 978 0 6 5008 0.00119808
490153 "chr21:35851107:A>G" "KCNE1" "NM_001270404:c.-50-29125T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs558964818" "This variant is a VUS because it does not have enough information."
490154 "chr21:35851124:G>T" "KCNE1" "NM_001270404:c.-50-29142C>A" "FIVE_PRIME_INTRON" "Benign" "rs75938311" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 49 1322 0.0371 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 50 5008 0.00998403
490155 "chr21:35851217:C>T" "KCNE1" "NM_001270404:c.-50-29235G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs532850935" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 3 1006 0.003 0 694 0 3 1008 0.003 0 978 0 7 5008 0.00139776
490156 "chr21:35851218:G>-" "KCNE1" "NM_001270404:c.-50-29236delC" "FIVE_PRIME_INTRON" "Unknown significance" "rs371639037" "This variant is a VUS because it does not have enough information."
490157 "chr21:35851218:G>C" "KCNE1" "NM_001270404:c.-50-29236C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs544807506" "This variant is a VUS because it does not have enough information."
490158 "chr21:35851220:G>C" "KCNE1" "NM_001270404:c.-50-29238C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs182439813" "This variant is a VUS because it does not have enough information." 3 1322 0.0023 0 1006 0 0 694 0 2 1008 0.002 4 978 0.0041 9 5008 0.00179712
490159 "chr21:35851226:T>G" "KCNE1" "NM_001270404:c.-50-29244A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs537158198" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 3 978 0.0031 3 5008 0.000599042
490160 "chr21:35851235:G>T" "KCNE1" "NM_001270404:c.-50-29253C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs188311382" "This variant is a VUS because it does not have enough information." 0 1322 0 4 1006 0.004 3 694 0.0043 0 1008 0 0 978 0 7 5008 0.00139776
490161 "chr21:35851280:A>G" "KCNE1" "NM_001270404:c.-50-29298T>C" "FIVE_PRIME_INTRON" "Benign" "rs577216292" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 6 978 0.0061 7 5008 0.00139776
490162 "chr21:35851283:C>T" "KCNE1" "NM_001270404:c.-50-29301G>A" "FIVE_PRIME_INTRON" "Benign" "rs191632298" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 8 1322 0.0061 0 1006 0 0 694 0 3 1008 0.003 0 978 0 11 5008 0.00219649
490163 "chr21:35851301:C>T" "KCNE1" "NM_001270404:c.-50-29319G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs560121937" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490164 "chr21:35851314:A>G" "KCNE1" "NM_001270404:c.-50-29332T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs549217295" "This variant is a VUS because it does not have enough information."
490165 "chr21:35851317:A>G" "KCNE1" "NM_001270404:c.-50-29335T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs374280527" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 4 1008 0.004 0 978 0 4 5008 0.000798722
490166 "chr21:35851329:A>G" "KCNE1" "NM_001270404:c.-50-29347T>C" "FIVE_PRIME_INTRON" "Benign" "rs9984279" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 487 1322 0.3684 494 1006 0.4911 289 694 0.4164 349 1008 0.3462 506 978 0.5174 2125 5008 0.424321
490167 "chr21:35851361:A>C" "KCNE1" "NM_001270404:c.-50-29379T>G" "FIVE_PRIME_INTRON" "Benign" "rs117121369" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 161 1322 0.1218 91 1006 0.0905 65 694 0.0937 99 1008 0.0982 139 978 0.1421 555 5008 0.110823
490168 "chr21:35851424:T>G" "KCNE1" "NM_001270404:c.-50-29442A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs184115972" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490169 "chr21:35851441:A>G" "KCNE1" "NM_001270404:c.-50-29459T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs771029981" "This variant is a VUS because it does not have enough information."
490170 "chr21:35851452:T>A" "KCNE1" "NM_001270404:c.-50-29470A>T" "FIVE_PRIME_INTRON" "Benign" "rs59271683" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1 1322 0.0008 0 1006 0 0 694 0 100 1008 0.0992 3 978 0.0031 104 5008 0.0207668
490171 "chr21:35851462:C>T" "KCNE1" "NM_001270404:c.-50-29480G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs564203294" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490172 "chr21:35851476:C>T" "KCNE1" "NM_001270404:c.-50-29494G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs187619943" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490173 "chr21:35851508:G>A" "KCNE1" "NM_001270404:c.-50-29526C>T" "FIVE_PRIME_INTRON" "Benign" "rs143905683" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 37 1322 0.028 0 1006 0 0 694 0 0 1008 0 0 978 0 37 5008 0.00738818
490174 "chr21:35851510:A>G" "KCNE1" "NM_001270404:c.-50-29528T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs777072349" "This variant is a VUS because it does not have enough information."
490175 "chr21:35851537:C>T" "KCNE1" "NM_001270404:c.-50-29555G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs567692780" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490176 "chr21:35851540:C>G" "KCNE1" "NM_001270404:c.-50-29558G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs535379584" "This variant is a VUS because it does not have enough information." 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042
490177 "chr21:35851556:C>T" "KCNE1" "NM_001270404:c.-50-29574G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs575064832" "This variant is a VUS because it does not have enough information."
490178 "chr21:35851562:A>T" "KCNE1" "NM_001270404:c.-50-29580T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs778670132" "This variant is a VUS because it does not have enough information."
490179 "chr21:35851585:C>T" "KCNE1" "NM_001270404:c.-50-29603G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs550423573" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490180 "chr21:35851592:G>A" "KCNE1" "NM_001270404:c.-50-29610C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs568960793" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
490181 "chr21:35851593:C>T" "KCNE1" "NM_001270404:c.-50-29611G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs147276281" "This variant is a VUS because it does not have enough information."
490182 "chr21:35851610:G>A" "KCNE1" "NM_001270404:c.-50-29628C>T" "FIVE_PRIME_INTRON" "Benign" "rs74610198" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 10 1322 0.0076 64 1006 0.0636 51 694 0.0735 130 1008 0.129 59 978 0.0603 314 5008 0.0626997
490183 "chr21:35851630:A>G" "KCNE1" "NM_001270404:c.-50-29648T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs558825702" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490184 "chr21:35851645:A>G" "KCNE1" "NM_001270404:c.-50-29663T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs192061077" "This variant is a VUS because it does not have enough information." 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042
490185 "chr21:35851654:C>T" "KCNE1" "NM_001270404:c.-50-29672G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs371380358" "This variant is a VUS because it does not have enough information."
490186 "chr21:35851691:C>A" "KCNE1" "NM_001270404:c.-50-29709G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs765515411" "This variant is a VUS because it does not have enough information."
490187 "chr21:35851709:A>G" "KCNE1" "NM_001270404:c.-50-29727T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs185766292" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
490188 "chr21:35851711:A>G" "KCNE1" "NM_001270404:c.-50-29729T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs190244597" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
490189 "chr21:35851752:T>G" "KCNE1" "NM_001270404:c.-50-29770A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs771526546" "This variant is a VUS because it does not have enough information."
490190 "chr21:35851789:G>C" "KCNE1" "NM_001270404:c.-50-29807C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs375243826" "This variant is a VUS because it does not have enough information."
490191 "chr21:35851824:T>C" "KCNE1" "NM_001270404:c.-50-29842A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs775983099" "This variant is a VUS because it does not have enough information."
490192 "chr21:35851868:A>G" "KCNE1" "NM_001270404:c.-50-29886T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs763242253" "This variant is a VUS because it does not have enough information."
490193 "chr21:35851878:A>C" "KCNE1" "NM_001270404:c.-50-29896T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs763739370" "This variant is a VUS because it does not have enough information."
490194 "chr21:35851881:A>T" "KCNE1" "NM_001270404:c.-50-29899T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs574848784" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490195 "chr21:35851886:T>C" "KCNE1" "NM_001270404:c.-50-29904A>G" "FIVE_PRIME_INTRON" "Benign" "rs80288122" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 2 1322 0.0015 61 1006 0.0606 21 694 0.0303 1 1008 0.001 23 978 0.0235 108 5008 0.0215655
490196 "chr21:35851924:C>T" "KCNE1" "NM_001270404:c.-50-29942G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs756783641" "This variant is a VUS because it does not have enough information."
490197 "chr21:35851941:C>T" "KCNE1" "NM_001270404:c.-50-29959G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs373642315" "This variant is a VUS because it does not have enough information."
490198 "chr21:35851947:T>G" "KCNE1" "NM_001270404:c.-50-29965A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs539900015" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 2 5008 0.000399361
490199 "chr21:35851952:G>A" "KCNE1" "NM_001270404:c.-50-29970C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs750350569" "This variant is a VUS because it does not have enough information."
490200 "chr21:35851963:G>A" "KCNE1" "NM_001270404:c.-50-29981C>T" "FIVE_PRIME_INTRON" "Benign" "rs140474143" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 37 1322 0.028 0 1006 0 0 694 0 0 1008 0 0 978 0 37 5008 0.00738818
490201 "chr21:35851983:C>A" "KCNE1" "NM_001270404:c.-50-30001G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs546367401" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490202 "chr21:35851991:A>G" "KCNE1" "NM_001270404:c.-50-30009T>C" "FIVE_PRIME_INTRON" "Benign" "rs149719427" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 7 1322 0.0053 0 1006 0 0 694 0 0 1008 0 0 978 0 7 5008 0.00139776
490203 "chr21:35851994:C>T" "KCNE1" "NM_001270404:c.-50-30012G>A" "FIVE_PRIME_INTRON" "Benign" "rs145595596" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 26 1322 0.0197 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 27 5008 0.00539137
490204 "chr21:35852002:C>T" "KCNE1" "NM_001270404:c.-50-30020G>A" "FIVE_PRIME_INTRON" "Benign" "rs180935164" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 7 1006 0.007 2 694 0.0029 0 1008 0 0 978 0 9 5008 0.00179712
490205 "chr21:35852008:C>T" "KCNE1" "NM_001270404:c.-50-30026G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs537251981" "This variant is a VUS because it does not have enough information."
490206 "chr21:35852024:->A" "KCNE1" "NM_001270404:c.-50-30042_-50-30041insT" "FIVE_PRIME_INTRON" "Unknown significance" "rs35678444" "This variant is a VUS because it does not have enough information."
490207 "chr21:35852042:A>C" "KCNE1" "NM_001270404:c.-50-30060T>G" "FIVE_PRIME_INTRON" "Benign" "rs561355669" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1 1322 0.0008 2 1006 0.002 2 694 0.0029 3 1008 0.003 22 978 0.0225 30 5008 0.00599042
490208 "chr21:35852045:->C" "KCNE1" "NM_001270404:c.-50-30063_-50-30062insG" "FIVE_PRIME_INTRON" "Unknown significance" "rs34541643" "This variant is a VUS because it does not have enough information."
490209 "chr21:35852047:C>T" "KCNE1" "NM_001270404:c.-50-30065G>A" "FIVE_PRIME_INTRON" "Benign" "rs13048556" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 66 1322 0.0499 222 1006 0.2207 115 694 0.1657 141 1008 0.1399 126 978 0.1288 670 5008 0.133786
490210 "chr21:35852047:CA>TG" "KCNE1" "Unknown significance" "rs386818152" "This variant is a VUS because it does not have enough information."
490211 "chr21:35852048:A>G" "KCNE1" "NM_001270404:c.-50-30066T>C" "FIVE_PRIME_INTRON" "Benign" "rs13048457" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 66 1322 0.0499 238 1006 0.2366 122 694 0.1758 141 1008 0.1399 127 978 0.1299 694 5008 0.138578
490212 "chr21:35852049:->TG" "KCNE1" "NM_001270404:c.-50-30067_-50-30066insCA" "FIVE_PRIME_INTRON" "Unknown significance" "rs34541643" "This variant is a VUS because it does not have enough information."
490213 "chr21:35852049:G>T" "KCNE1" "NM_001270404:c.-50-30067C>A" "FIVE_PRIME_INTRON" "Benign" "rs569125824" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1 1322 0.0008 1 1006 0.001 1 694 0.0014 3 1008 0.003 22 978 0.0225 28 5008 0.00559105
490214 "chr21:35852063:C>T" "KCNE1" "NM_001270404:c.-50-30081G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs533015767" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490215 "chr21:35852064:G>A" "KCNE1" "NM_001270404:c.-50-30082C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs541359641" "This variant is a VUS because it does not have enough information."
490216 "chr21:35852073:G>A" "KCNE1" "NM_001270404:c.-50-30091C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs375701190" "This variant is a VUS because it does not have enough information."
490217 "chr21:35852090:G>A" "KCNE1" "NM_001270404:c.-50-30108C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs184121351" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490218 "chr21:35852126:C>T" "KCNE1" "NM_001270404:c.-50-30144G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs770974988" "This variant is a VUS because it does not have enough information."
490219 "chr21:35852127:G>A" "KCNE1" "NM_001270404:c.-50-30145C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs369750435" "This variant is a VUS because it does not have enough information."
490220 "chr21:35852134:T>C" "KCNE1" "NM_001270404:c.-50-30152A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs566640953" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490221 "chr21:35852141:A>T" "KCNE1" "NM_001270404:c.-50-30159T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs535135586" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490222 "chr21:35852144:C>T" "KCNE1" "NM_001270404:c.-50-30162G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs8132636" "This variant is a VUS because it does not have enough information."
490223 "chr21:35852145:A>G" "KCNE1" "NM_001270404:c.-50-30163T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs553460809" "This variant is a VUS because it does not have enough information." 4 1322 0.003 0 1006 0 0 694 0 0 1008 0 0 978 0 4 5008 0.000798722
490224 "chr21:35852181:G>T" "KCNE1" "NM_001270404:c.-50-30199C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs776759019" "This variant is a VUS because it does not have enough information."
490225 "chr21:35852184:C>T" "KCNE1" "NM_001270404:c.-50-30202G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs188139797" "This variant is a VUS because it does not have enough information." 0 1322 0 4 1006 0.004 0 694 0 0 1008 0 0 978 0 4 5008 0.000798722
490226 "chr21:35852185:G>A" "KCNE1" "NM_001270404:c.-50-30203C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs181326977" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490227 "chr21:35852189:C>T" "KCNE1" "NM_001270404:c.-50-30207G>A" "FIVE_PRIME_INTRON" "Benign" "rs557408934" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 11 1322 0.0083 0 1006 0 0 694 0 0 1008 0 0 978 0 11 5008 0.00219649
490228 "chr21:35852232:C>T" "KCNE1" "NM_001270404:c.-50-30250G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs538474521" "This variant is a VUS because it does not have enough information."
490229 "chr21:35852274:A>G" "KCNE1" "NM_001270404:c.-50-30292T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs775867235" "This variant is a VUS because it does not have enough information."
490230 "chr21:35852278:G>A" "KCNE1" "NM_001270404:c.-50-30296C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs185406754" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490231 "chr21:35852288:G>A" "KCNE1" "NM_001270404:c.-50-30306C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs546152865" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490232 "chr21:35852294:G>A" "KCNE1" "NM_001270404:c.-50-30312C>T" "FIVE_PRIME_INTRON" "Benign" "rs140838093" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 37 1322 0.028 0 1006 0 0 694 0 0 1008 0 0 978 0 37 5008 0.00738818
490233 "chr21:35852308:T>C" "KCNE1" "NM_001270404:c.-50-30326A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs763340860" "This variant is a VUS because it does not have enough information."
490234 "chr21:35852320:G>A" "KCNE1" "NM_001270404:c.-50-30338C>T" "FIVE_PRIME_INTRON" "Benign" "rs573060604" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 0 1008 0 11 978 0.0112 11 5008 0.00219649
490235 "chr21:35852353:G>A" "KCNE1" "NM_001270404:c.-50-30371C>T" "FIVE_PRIME_INTRON" "Benign" "rs144641036" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 37 1322 0.028 0 1006 0 0 694 0 0 1008 0 0 978 0 37 5008 0.00738818
490236 "chr21:35852439:G>A" "KCNE1" "NM_001270404:c.-50-30457C>T" "FIVE_PRIME_INTRON" "Benign" "rs146702132" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 49 1322 0.0371 0 1006 0 0 694 0 0 1008 0 0 978 0 49 5008 0.00978435
490237 "chr21:35852446:A>G" "KCNE1" "NM_001270404:c.-50-30464T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs545334190" "This variant is a VUS because it does not have enough information."
490238 "chr21:35852458:G>A" "KCNE1" "NM_001270404:c.-50-30476C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs552532050" "This variant is a VUS because it does not have enough information."
490239 "chr21:35852500:G>A" "KCNE1" "NM_001270404:c.-50-30518C>T" "FIVE_PRIME_INTRON" "Benign" "rs8133294" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 14 1322 0.0106 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 16 5008 0.00319489
490240 "chr21:35852507:C>A" "KCNE1" "NM_001270404:c.-50-30525G>T" "FIVE_PRIME_INTRON" "Benign" "rs76394386" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 49 1322 0.0371 0 1006 0 0 694 0 0 1008 0 0 978 0 49 5008 0.00978435
490241 "chr21:35852509:C>A" "KCNE1" "NM_001270404:c.-50-30527G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs372514613" "This variant is a VUS because it does not have enough information." 3 1322 0.0023 0 1006 0 0 694 0 2 1008 0.002 4 978 0.0041 9 5008 0.00179712
490242 "chr21:35852509:C>T" "KCNE1" "NM_001270404:c.-50-30527G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs372514613" "This variant is a VUS because it does not have enough information."
490243 "chr21:35852529:G>A" "KCNE1" "NM_001270404:c.-50-30547C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs533277397" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490244 "chr21:35852534:A>G" "KCNE1" "NM_001270404:c.-50-30552T>C" "FIVE_PRIME_INTRON" "Benign" "rs151258713" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 10 1322 0.0076 64 1006 0.0636 51 694 0.0735 136 1008 0.1349 59 978 0.0603 320 5008 0.0638978
490245 "chr21:35852540:G>A" "KCNE1" "NM_001270404:c.-50-30558C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs566680313" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 2 1006 0.002 1 694 0.0014 0 1008 0 0 978 0 4 5008 0.000798722
490246 "chr21:35852558:C>T" "KCNE1" "NM_001270404:c.-50-30576G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs767127259" "This variant is a VUS because it does not have enough information."
490247 "chr21:35852564:G>A" "KCNE1" "NM_001270404:c.-50-30582C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs527436180" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490248 "chr21:35852614:A>G" "KCNE1" "NM_001270404:c.-50-30632T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs41315447" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490249 "chr21:35852636:A>G" "KCNE1" "NM_001270404:c.-50-30654T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs568556579" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490250 "chr21:35852646:T>C" "KCNE1" "NM_001270404:c.-50-30664A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs535514203" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490251 "chr21:35852681:C>T" "KCNE1" "NM_001270404:c.-50-30699G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs563246417" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490252 "chr21:35852770:A>G" "KCNE1" "NM_001270404:c.-51+30629T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs569124204" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490253 "chr21:35852775:C>A" "KCNE1" "NM_001270404:c.-51+30624G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs41312385" "This variant is a VUS because it does not have enough information."
490254 "chr21:35852789:T>C" "KCNE1" "NM_001270404:c.-51+30610A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs755588880" "This variant is a VUS because it does not have enough information."
490255 "chr21:35852793:T>G" "KCNE1" "NM_001270404:c.-51+30606A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs370040511" "This variant is a VUS because it does not have enough information."
490256 "chr21:35852799:G>A" "KCNE1" "NM_001270404:c.-51+30600C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs374379210" "This variant is a VUS because it does not have enough information."
490257 "chr21:35852818:T>C" "KCNE1" "NM_001270404:c.-51+30581A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs766271141" "This variant is a VUS because it does not have enough information."
490258 "chr21:35852827:G>A" "KCNE1" "NM_001270404:c.-51+30572C>T" "FIVE_PRIME_INTRON" "Benign" "rs190614058" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 7 1008 0.0069 1 978 0.001 8 5008 0.00159744
490259 "chr21:35852835:C>T" "KCNE1" "NM_001270404:c.-51+30564G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs113757962" "This variant is a VUS because it does not have enough information."
490260 "chr21:35852836:T>-" "KCNE1" "NM_001270404:c.-51+30563delA" "FIVE_PRIME_INTRON" "Unknown significance" "rs369821890" "This variant is a VUS because it does not have enough information."
490261 "chr21:35852852:G>A" "KCNE1" "NM_001270404:c.-51+30547C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs377323748" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 4 1008 0.004 1 978 0.001 6 5008 0.00119808
490262 "chr21:35852886:T>G" "KCNE1" "NM_001270404:c.-51+30513A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs12482762" "This variant is a VUS because it does not have enough information."
490263 "chr21:35852889:G>A" "KCNE1" "NM_001270404:c.-51+30510C>T" "FIVE_PRIME_INTRON" "Benign" "rs8128760" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 116 1322 0.0877 0 1006 0 10 694 0.0144 0 1008 0 0 978 0 126 5008 0.0251597
490264 "chr21:35852892:C>T" "KCNE1" "NM_001270404:c.-51+30507G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs181569753" "This variant is a VUS because it does not have enough information."
490265 "chr21:35852893:G>A" "KCNE1" "NM_001270404:c.-51+30506C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs530682159" "This variant is a VUS because it does not have enough information."
490266 "chr21:35852902:C>T" "KCNE1" "NM_001270404:c.-51+30497G>A" "FIVE_PRIME_INTRON" "Benign" "rs116384471" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 47 1322 0.0356 0 1006 0 2 694 0.0029 7 1008 0.0069 0 978 0 56 5008 0.0111821
490267 "chr21:35852903:G>A" "KCNE1" "NM_001270404:c.-51+30496C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs753748157" "This variant is a VUS because it does not have enough information."
490268 "chr21:35852915:G>A" "KCNE1" "NM_001270404:c.-51+30484C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs561105389" "This variant is a VUS because it does not have enough information."
490269 "chr21:35852928:G>C" "KCNE1" "NM_001270404:c.-51+30471C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs13052680" "This variant is a VUS because it does not have enough information."
490270 "chr21:35852946:G>A" "KCNE1" "NM_001270404:c.-51+30453C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs555079801" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361
490271 "chr21:35852965:->C" "KCNE1" "NM_001270404:c.-51+30434_-51+30435insG" "FIVE_PRIME_INTRON" "Unknown significance" "rs35932510" "This variant is a VUS because it does not have enough information."
490272 "chr21:35852965:C>T" "KCNE1" "NM_001270404:c.-51+30434G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs573382230" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490273 "chr21:35852974:C>T" "KCNE1" "NM_001270404:c.-51+30425G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs543943367" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
490274 "chr21:35852979:G>T" "KCNE1" "NM_001270404:c.-51+30420C>A" "FIVE_PRIME_INTRON" "Benign" "rs187498195" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 1 694 0.0014 11 1008 0.0109 0 978 0 12 5008 0.00239617
490275 "chr21:35852979:G>A" "KCNE1" "NM_001270404:c.-51+30420C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs187498195" "This variant is a VUS because it does not have enough information."
490276 "chr21:35853013:G>A" "KCNE1" "NM_001270404:c.-51+30386C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs546944191" "This variant is a VUS because it does not have enough information."
490277 "chr21:35853039:T>A" "KCNE1" "NM_001270404:c.-51+30360A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs566050343" "This variant is a VUS because it does not have enough information." 0 1322 0 2 1006 0.002 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
490278 "chr21:35853043:G>A" "KCNE1" "NM_001270404:c.-51+30356C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs545288932" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490279 "chr21:35853044:A>T" "KCNE1" "NM_001270404:c.-51+30355T>A" "FIVE_PRIME_INTRON" "Benign" "rs149430250" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 123 1322 0.093 0 1006 0 9 694 0.013 0 1008 0 0 978 0 132 5008 0.0263578
490280 "chr21:35853054:C>A" "KCNE1" "NM_001270404:c.-51+30345G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs191829443" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 1 694 0.0014 0 1008 0 0 978 0 2 5008 0.000399361
490281 "chr21:35853091:G>T" "KCNE1" "NM_001270404:c.-51+30308C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs549182870" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490282 "chr21:35853111:C>A" "KCNE1" "NM_001270404:c.-51+30288G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs562191226" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 2 978 0.002 2 5008 0.000399361
490283 "chr21:35853119:G>A" "KCNE1" "NM_001270404:c.-51+30280C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs182877688" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490284 "chr21:35853134:A>G" "KCNE1" "NM_001270404:c.-51+30265T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs550758623" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 2 5008 0.000399361
490285 "chr21:35853135:T>A" "KCNE1" "NM_001270404:c.-51+30264A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs759438778" "This variant is a VUS because it does not have enough information."
490286 "chr21:35853176:T>C" "KCNE1" "NM_001270404:c.-51+30223A>G" "FIVE_PRIME_INTRON" "Benign" "rs2834489" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 77 1322 0.0582 337 1006 0.335 166 694 0.2392 112 1008 0.1111 313 978 0.32 1005 5008 0.200679
490287 "chr21:35853185:G>A" "KCNE1" "NM_001270404:c.-51+30214C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs373877091" "This variant is a VUS because it does not have enough information."
490288 "chr21:35853203:T>G" "KCNE1" "NM_001270404:c.-51+30196A>C" "FIVE_PRIME_INTRON" "Benign" "rs75996138" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 123 1322 0.093 0 1006 0 9 694 0.013 0 1008 0 0 978 0 132 5008 0.0263578
490289 "chr21:35853240:T>A" "KCNE1" "NM_001270404:c.-51+30159A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs147122939" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490290 "chr21:35853250:T>C" "KCNE1" "NM_001270404:c.-51+30149A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs774761365" "This variant is a VUS because it does not have enough information."
490291 "chr21:35853273:T>C" "KCNE1" "NM_001270404:c.-51+30126A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs566811264" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490292 "chr21:35853285:C>T" "KCNE1" "NM_001270404:c.-51+30114G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs534153527" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 3 978 0.0031 3 5008 0.000599042
490293 "chr21:35853289:T>C" "KCNE1" "NM_001270404:c.-51+30110A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs762147578" "This variant is a VUS because it does not have enough information."
490294 "chr21:35853320:T>A" "KCNE1" "NM_001270404:c.-51+30079A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs138259668" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490295 "chr21:35853376:T>C" "KCNE1" "NM_001270404:c.-51+30023A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs574115955" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490296 "chr21:35853407:T>C" "KCNE1" "NM_001270404:c.-51+29992A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs537952355" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490297 "chr21:35853428:C>T" "KCNE1" "NM_001270404:c.-51+29971G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs376813324" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361
490298 "chr21:35853471:C>T" "KCNE1" "NM_001270404:c.-51+29928G>A" "FIVE_PRIME_INTRON" "Benign" "rs11910404" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 172 1322 0.1301 0 1006 0 7 694 0.0101 20 1008 0.0198 39 978 0.0399 238 5008 0.047524
490299 "chr21:35853474:T>C" "KCNE1" "NM_001270404:c.-51+29925A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs544668276" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490300 "chr21:35853485:C>T" "KCNE1" "NM_001270404:c.-51+29914G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs560473906" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490301 "chr21:35853488:C>G" "KCNE1" "NM_001270404:c.-51+29911G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs776019894" "This variant is a VUS because it does not have enough information."
490302 "chr21:35853530:T>C" "KCNE1" "NM_001270404:c.-51+29869A>G" "FIVE_PRIME_INTRON" "Benign" "rs116130638" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 41 1322 0.031 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 42 5008 0.00838658
490303 "chr21:35853539:G>A" "KCNE1" "NM_001270404:c.-51+29860C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs537592097" "This variant is a VUS because it does not have enough information."
490304 "chr21:35853623:T>G" "KCNE1" "NM_001270404:c.-51+29776A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs542910717" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490305 "chr21:35853628:T>C" "KCNE1" "NM_001270404:c.-51+29771A>G" "FIVE_PRIME_INTRON" "Benign" "rs6517233" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 313 1322 0.2368 559 1006 0.5557 282 694 0.4063 257 1008 0.255 442 978 0.4519 1853 5008 0.370008
490306 "chr21:35853634:C>T" "KCNE1" "NM_001270404:c.-51+29765G>A" "FIVE_PRIME_INTRON" "Benign" "rs372364868" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 38 1322 0.0287 0 1006 0 3 694 0.0043 0 1008 0 0 978 0 41 5008 0.0081869
490307 "chr21:35853635:G>A" "KCNE1" "NM_001270404:c.-51+29764C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs551101574" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490308 "chr21:35853653:T>G" "KCNE1" "NM_001270404:c.-51+29746A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs767664491" "This variant is a VUS because it does not have enough information."
490309 "chr21:35853655:C>T" "KCNE1" "NM_001270404:c.-51+29744G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs750544774" "This variant is a VUS because it does not have enough information."
490310 "chr21:35853696:C>G" "KCNE1" "NM_001270404:c.-51+29703G>C" "FIVE_PRIME_INTRON" "Benign" "rs11911111" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 210 1322 0.1589 0 1006 0 7 694 0.0101 37 1008 0.0367 48 978 0.0491 302 5008 0.0603035
490311 "chr21:35853697:G>A" "KCNE1" "NM_001270404:c.-51+29702C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs113575719" "This variant is a VUS because it does not have enough information."
490312 "chr21:35853703:C>T" "KCNE1" "NM_001270404:c.-51+29696G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs533401468" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490313 "chr21:35853704:G>A" "KCNE1" "NM_001270404:c.-51+29695C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs370335767" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490314 "chr21:35853721:G>A" "KCNE1" "NM_001270404:c.-51+29678C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs566501945" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490315 "chr21:35853729:G>A" "KCNE1" "NM_001270404:c.-51+29670C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs534235233" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490316 "chr21:35853741:C>T" "KCNE1" "NM_001270404:c.-51+29658G>A" "FIVE_PRIME_INTRON" "Benign" "rs113951705" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 69 1322 0.0522 1 1006 0.001 1 694 0.0014 2 1008 0.002 4 978 0.0041 77 5008 0.0153754
490317 "chr21:35853749:G>A" "KCNE1" "NM_001270404:c.-51+29650C>T" "FIVE_PRIME_INTRON" "Benign" "rs8133365" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 144 1322 0.1089 558 1006 0.5547 281 694 0.4049 255 1008 0.253 438 978 0.4479 1676 5008 0.334665
490318 "chr21:35853765:A>C" "KCNE1" "NM_001270404:c.-51+29634T>G" "FIVE_PRIME_INTRON" "Benign" "rs113407110" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 12 1322 0.0091 64 1006 0.0636 52 694 0.0749 135 1008 0.1339 59 978 0.0603 322 5008 0.0642971
490319 "chr21:35853779:->AA" "KCNE1" "NM_001270404:c.-51+29620_-51+29621insTT" "FIVE_PRIME_INTRON" "Unknown significance" "rs58158591" "This variant is a VUS because it does not have enough information."
490320 "chr21:35853779:AA>-" "KCNE1" "NM_001270404:c.-51+29620_-51+29623delTT" "FIVE_PRIME_INTRON" "Unknown significance" "rs10544229" "This variant is a VUS because it does not have enough information."
490321 "chr21:35853805:C>T" "KCNE1" "NM_001270404:c.-51+29594G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs139163056" "This variant is a VUS because it does not have enough information."
490322 "chr21:35853807:T>C" "KCNE1" "NM_001270404:c.-51+29592A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs556264037" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 1 978 0.001 3 5008 0.000599042
490323 "chr21:35853811:A>C" "KCNE1" "NM_001270404:c.-51+29588T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs367950400" "This variant is a VUS because it does not have enough information."
490324 "chr21:35853850:A>G" "KCNE1" "NM_001270404:c.-51+29549T>C" "FIVE_PRIME_INTRON" "Benign" "rs149954173" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 7 1322 0.0053 0 1006 0 0 694 0 0 1008 0 0 978 0 7 5008 0.00139776
490325 "chr21:35853899:G>A" "KCNE1" "NM_001270404:c.-51+29500C>T" "FIVE_PRIME_INTRON" "Benign" "rs78607029" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 10 1322 0.0076 64 1006 0.0636 51 694 0.0735 135 1008 0.1339 59 978 0.0603 319 5008 0.0636981
490326 "chr21:35853932:T>C" "KCNE1" "NM_001270404:c.-51+29467A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs368445245" "This variant is a VUS because it does not have enough information."
490327 "chr21:35853933:G>T" "KCNE1" "NM_001270404:c.-51+29466C>A" "FIVE_PRIME_INTRON" "Benign" "rs146035538" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 9 1008 0.0089 0 978 0 9 5008 0.00179712
490328 "chr21:35853985:T>C" "KCNE1" "NM_001270404:c.-51+29414A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs755421727" "This variant is a VUS because it does not have enough information."
490329 "chr21:35853989:T>G" "KCNE1" "NM_001270404:c.-51+29410A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs572030944" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490330 "chr21:35854027:C>T" "KCNE1" "NM_001270404:c.-51+29372G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs185505562" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490331 "chr21:35854048:G>A" "KCNE1" "NM_001270404:c.-51+29351C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs11911291" "This variant is a VUS because it does not have enough information."
490332 "chr21:35854078:C>T" "KCNE1" "NM_001270404:c.-51+29321G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs554565659" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 2 978 0.002 2 5008 0.000399361
490333 "chr21:35854122:G>A" "KCNE1" "NM_001270404:c.-51+29277C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs537495640" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490334 "chr21:35854127:G>C" "KCNE1" "NM_001270404:c.-51+29272C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs543239623" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
490335 "chr21:35854206:G>A" "KCNE1" "NM_001270404:c.-51+29193C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs563030054" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490336 "chr21:35854208:G>A" "KCNE1" "NM_001270404:c.-51+29191C>T" "FIVE_PRIME_INTRON" "Benign" "rs139799071" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 38 1322 0.0287 0 1006 0 0 694 0 0 1008 0 0 978 0 38 5008 0.00758786
490337 "chr21:35854218:G>T" "KCNE1" "NM_001270404:c.-51+29181C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs368794641" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490338 "chr21:35854225:G>A" "KCNE1" "NM_001270404:c.-51+29174C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs779170777" "This variant is a VUS because it does not have enough information."
490339 "chr21:35854334:C>A" "KCNE1" "NM_001270404:c.-51+29065G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs774918801" "This variant is a VUS because it does not have enough information."
490340 "chr21:35854366:G>C" "KCNE1" "NM_001270404:c.-51+29033C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs560121405" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490341 "chr21:35854376:G>A" "KCNE1" "NM_001270404:c.-51+29023C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs527630365" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490342 "chr21:35854403:T>A" "KCNE1" "NM_001270404:c.-51+28996A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs549310359" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490343 "chr21:35854413:C>T" "KCNE1" "NM_001270404:c.-51+28986G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs761540374" "This variant is a VUS because it does not have enough information."
490344 "chr21:35854425:G>A" "KCNE1" "NM_001270404:c.-51+28974C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs771789834" "This variant is a VUS because it does not have enough information."
490345 "chr21:35854431:G>T" "KCNE1" "NM_001270404:c.-51+28968C>A" "FIVE_PRIME_INTRON" "Benign" "rs571712825" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 7 1322 0.0053 0 1006 0 0 694 0 0 1008 0 0 978 0 7 5008 0.00139776
490346 "chr21:35854488:G>A" "KCNE1" "NM_001270404:c.-51+28911C>T" "FIVE_PRIME_INTRON" "Benign" "rs372519098" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 10 1008 0.0099 0 978 0 10 5008 0.00199681
490347 "chr21:35854516:C>G" "KCNE1" "NM_001270404:c.-51+28883G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs189774462" "This variant is a VUS because it does not have enough information." 5 1322 0.0038 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 6 5008 0.00119808
490348 "chr21:35854557:C>A" "KCNE1" "NM_001270404:c.-51+28842G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs28523330" "This variant is a VUS because it does not have enough information."
490349 "chr21:35854558:->A" "KCNE1" "NM_001270404:c.-51+28841_-51+28842insT" "FIVE_PRIME_INTRON" "Unknown significance" "rs373981020" "This variant is a VUS because it does not have enough information."
490350 "chr21:35854558:A>-" "KCNE1" "NM_001270404:c.-51+28841delT" "FIVE_PRIME_INTRON" "Unknown significance" "rs151107642" "This variant is a VUS because it does not have enough information."
490351 "chr21:35854597:T>C" "KCNE1" "NM_001270404:c.-51+28802A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs747763042" "This variant is a VUS because it does not have enough information."
490352 "chr21:35854599:T>G" "KCNE1" "NM_001270404:c.-51+28800A>C" "FIVE_PRIME_INTRON" "Benign" "rs2834490" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 77 1322 0.0582 336 1006 0.334 166 694 0.2392 115 1008 0.1141 313 978 0.32 1007 5008 0.201078
490353 "chr21:35854605:A>C" "KCNE1" "NM_001270404:c.-51+28794T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs538749257" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490354 "chr21:35854619:G>C" "KCNE1" "NM_001270404:c.-51+28780C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs553858380" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 1 1008 0.001 0 978 0 2 5008 0.000399361
490355 "chr21:35854622:G>A" "KCNE1" "NM_001270404:c.-51+28777C>T" "FIVE_PRIME_INTRON" "Benign" "rs565726540" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 0 1008 0 5 978 0.0051 5 5008 0.000998403
490356 "chr21:35854682:A>G" "KCNE1" "NM_001270404:c.-51+28717T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs575236394" "This variant is a VUS because it does not have enough information."
490357 "chr21:35854698:->C" "KCNE1" "NM_001270404:c.-51+28701_-51+28702insG" "FIVE_PRIME_INTRON" "Unknown significance" "rs533186176" "This variant is a VUS because it does not have enough information." 3 1322 0.0023 0 1006 0 0 694 0 1 1008 0.001 0 978 0 4 5008 0.000798722
490358 "chr21:35854698:C>-" "KCNE1" "NM_001270404:c.-51+28701delG" "FIVE_PRIME_INTRON" "Unknown significance" "rs562151115" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490359 "chr21:35854698:C>T" "KCNE1" "NM_001270404:c.-51+28701G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs369206858" "This variant is a VUS because it does not have enough information."
490360 "chr21:35854706:C>A" "KCNE1" "NM_001270404:c.-51+28693G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs536246190" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490361 "chr21:35854710:G>T" "KCNE1" "NM_001270404:c.-51+28689C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs200786005" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 4 1008 0.004 0 978 0 4 5008 0.000798722
490362 "chr21:35854751:C>T" "KCNE1" "NM_001270404:c.-51+28648G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs576238392" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490363 "chr21:35854763:G>C" "KCNE1" "NM_001270404:c.-51+28636C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs543675482" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361
490364 "chr21:35854779:C>T" "KCNE1" "NM_001270404:c.-51+28620G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs760190223" "This variant is a VUS because it does not have enough information."
490365 "chr21:35854835:G>-" "KCNE1" "NM_001270404:c.-51+28564delC" "FIVE_PRIME_INTRON" "Benign" "rs201813076" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 37 1322 0.028 0 1006 0 0 694 0 0 1008 0 0 978 0 37 5008 0.00738818
490366 "chr21:35854857:C>A" "KCNE1" "NM_001270404:c.-51+28542G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs182767472" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490367 "chr21:35854858:G>A" "KCNE1" "NM_001270404:c.-51+28541C>T" "FIVE_PRIME_INTRON" "Benign" "rs2834491" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 10 1322 0.0076 65 1006 0.0646 54 694 0.0778 135 1008 0.1339 59 978 0.0603 323 5008 0.0644968
490368 "chr21:35854891:A>G" "KCNE1" "NM_001270404:c.-51+28508T>C" "FIVE_PRIME_INTRON" "Benign" "rs143169630" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 20 1008 0.0198 0 978 0 20 5008 0.00399361
490369 "chr21:35854903:G>A" "KCNE1" "NM_001270404:c.-51+28496C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs560207199" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490370 "chr21:35854934:G>A" "KCNE1" "NM_001270404:c.-51+28465C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs561041695" "This variant is a VUS because it does not have enough information."
490371 "chr21:35854938:G>A" "KCNE1" "NM_001270404:c.-51+28461C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs187056802" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
490372 "chr21:35854954:T>C" "KCNE1" "NM_001270404:c.-51+28445A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs759509208" "This variant is a VUS because it does not have enough information."
490373 "chr21:35854962:G>A" "KCNE1" "NM_001270404:c.-51+28437C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs765004616" "This variant is a VUS because it does not have enough information."
490374 "chr21:35854972:G>A" "KCNE1" "NM_001270404:c.-51+28427C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs369096970" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 2 978 0.002 2 5008 0.000399361
490375 "chr21:35855003:C>T" "KCNE1" "NM_001270404:c.-51+28396G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs752433025" "This variant is a VUS because it does not have enough information."
490376 "chr21:35855004:G>A" "KCNE1" "NM_001270404:c.-51+28395C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs758195238" "This variant is a VUS because it does not have enough information."
490377 "chr21:35855009:A>T" "KCNE1" "NM_001270404:c.-51+28390T>A" "FIVE_PRIME_INTRON" "Benign" "rs112262137" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 38 1322 0.0287 0 1006 0 3 694 0.0043 0 1008 0 0 978 0 41 5008 0.0081869
490378 "chr21:35855028:G>A" "KCNE1" "NM_001270404:c.-51+28371C>T" "FIVE_PRIME_INTRON" "Benign" "rs114049892" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 52 1322 0.0393 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 53 5008 0.0105831
490379 "chr21:35855069:G>A" "KCNE1" "NM_001270404:c.-51+28330C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs7278969" "This variant is a VUS because it does not have enough information."
490380 "chr21:35855081:C>A" "KCNE1" "NM_001270404:c.-51+28318G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs373497323" "This variant is a VUS because it does not have enough information."
490381 "chr21:35855096:C>T" "KCNE1" "NM_001270404:c.-51+28303G>A" "FIVE_PRIME_INTRON" "Benign" "rs79169756" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 12 1006 0.0119 3 694 0.0043 0 1008 0 0 978 0 15 5008 0.00299521
490382 "chr21:35855145:G>A" "KCNE1" "NM_001270404:c.-51+28254C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs571752530" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490383 "chr21:35855151:C>T" "KCNE1" "NM_001270404:c.-51+28248G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs142588578" "This variant is a VUS because it does not have enough information."
490384 "chr21:35855152:G>A" "KCNE1" "NM_001270404:c.-51+28247C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs750635025" "This variant is a VUS because it does not have enough information."
490385 "chr21:35855153:C>T" "KCNE1" "NM_001270404:c.-51+28246G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs532751983" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
490386 "chr21:35855191:C>T" "KCNE1" "NM_001270404:c.-51+28208G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs770766744" "This variant is a VUS because it does not have enough information."
490387 "chr21:35855221:A>G" "KCNE1" "NM_001270404:c.-51+28178T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs776667946" "This variant is a VUS because it does not have enough information."
490388 "chr21:35855233:T>C" "KCNE1" "NM_001270404:c.-51+28166A>G" "FIVE_PRIME_INTRON" "Benign" "rs193168473" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 8 978 0.0082 9 5008 0.00179712
490389 "chr21:35855292:T>A" "KCNE1" "NM_001270404:c.-51+28107A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs540497080" "This variant is a VUS because it does not have enough information."
490390 "chr21:35855295:A>G" "KCNE1" "NM_001270404:c.-51+28104T>C" "FIVE_PRIME_INTRON" "Benign" "rs2211697" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 516 1322 0.3903 64 1006 0.0636 75 694 0.1081 190 1008 0.1885 152 978 0.1554 997 5008 0.199081
490391 "chr21:35855323:T>A" "KCNE1" "NM_001270404:c.-51+28076A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs749801627" "This variant is a VUS because it does not have enough information."
490392 "chr21:35855342:G>A" "KCNE1" "NM_001270404:c.-51+28057C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs536284500" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490393 "chr21:35855356:G>-" "KCNE1" "NM_001270404:c.-51+28043delC" "FIVE_PRIME_INTRON" "Unknown significance" "rs529773420" "This variant is a VUS because it does not have enough information."
490394 "chr21:35855360:G>A" "KCNE1" "NM_001270404:c.-51+28039C>T" "FIVE_PRIME_INTRON" "Benign" "rs11908952" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 19 1322 0.0144 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 20 5008 0.00399361
490395 "chr21:35855376:A>T" "KCNE1" "NM_001270404:c.-51+28023T>A" "FIVE_PRIME_INTRON" "Benign" "rs114518269" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 116 1322 0.0877 0 1006 0 9 694 0.013 0 1008 0 0 978 0 125 5008 0.0249601
490396 "chr21:35855378:A>T" "KCNE1" "NM_001270404:c.-51+28021T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs369786218" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 4 1008 0.004 1 978 0.001 5 5008 0.000998403
490397 "chr21:35855388:C>A" "KCNE1" "NM_001270404:c.-51+28011G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs183253834" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490398 "chr21:35855426:C>T" "KCNE1" "NM_001270404:c.-51+27973G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs779572869" "This variant is a VUS because it does not have enough information."
490399 "chr21:35855440:T>C" "KCNE1" "NM_001270404:c.-51+27959A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs532485355" "This variant is a VUS because it does not have enough information."
490400 "chr21:35855553:C>T" "KCNE1" "NM_001270404:c.-51+27846G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs576671307" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490401 "chr21:35855595:C>T" "KCNE1" "NM_001270404:c.-51+27804G>A" "FIVE_PRIME_INTRON" "Benign" "rs116533684" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 76 1322 0.0575 0 1006 0 8 694 0.0115 0 1008 0 0 978 0 84 5008 0.0167732
490402 "chr21:35855600:T>C" "KCNE1" "NM_001270404:c.-51+27799A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs553882191" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490403 "chr21:35855604:T>A" "KCNE1" "NM_001270404:c.-51+27795A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs572185557" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490404 "chr21:35855624:A>G" "KCNE1" "NM_001270404:c.-51+27775T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs748453677" "This variant is a VUS because it does not have enough information."
490405 "chr21:35855636:C>T" "KCNE1" "NM_001270404:c.-51+27763G>A" "FIVE_PRIME_INTRON" "Benign" "rs76812610" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 147 1322 0.1112 0 1006 0 6 694 0.0086 0 1008 0 0 978 0 153 5008 0.0305511
490406 "chr21:35855642:C>T" "KCNE1" "NM_001270404:c.-51+27757G>A" "FIVE_PRIME_INTRON" "Benign" "rs189063957" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 7 1322 0.0053 0 1006 0 0 694 0 0 1008 0 0 978 0 7 5008 0.00139776
490407 "chr21:35855643:A>G" "KCNE1" "NM_001270404:c.-51+27756T>C" "FIVE_PRIME_INTRON" "Benign" "rs6517234" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 734 1322 0.5552 637 1006 0.6332 364 694 0.5245 447 1008 0.4435 597 978 0.6104 2779 5008 0.554912
490408 "chr21:35855643:A>C" "KCNE1" "NM_001270404:c.-51+27756T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs6517234" "This variant is a VUS because it does not have enough information."
490409 "chr21:35855655:G>A" "KCNE1" "NM_001270404:c.-51+27744C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs770444280" "This variant is a VUS because it does not have enough information."
490410 "chr21:35855670:G>A" "KCNE1" "NM_001270404:c.-51+27729C>T" "FIVE_PRIME_INTRON" "Benign" "rs76232737" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 36 1322 0.0272 0 1006 0 0 694 0 0 1008 0 0 978 0 36 5008 0.0071885
490411 "chr21:35855699:G>C" "KCNE1" "NM_001270404:c.-51+27700C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs776063323" "This variant is a VUS because it does not have enough information."
490412 "chr21:35855745:T>C" "KCNE1" "NM_001270404:c.-51+27654A>G" "FIVE_PRIME_INTRON" "Benign" "rs2834493" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 339 1322 0.2564 577 1006 0.5736 296 694 0.4265 257 1008 0.255 444 978 0.454 1913 5008 0.381989
490413 "chr21:35855750:C>G" "KCNE1" "NM_001270404:c.-51+27649G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs772481169" "This variant is a VUS because it does not have enough information."
490414 "chr21:35855778:G>A" "KCNE1" "NM_001270404:c.-51+27621C>T" "FIVE_PRIME_INTRON" "Benign" "rs140558902" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 27 1322 0.0204 3 1006 0.003 3 694 0.0043 0 1008 0 0 978 0 33 5008 0.00658946
490415 "chr21:35855793:A>G" "KCNE1" "NM_001270404:c.-51+27606T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs752664339" "This variant is a VUS because it does not have enough information."
490416 "chr21:35855817:G>A" "KCNE1" "NM_001270404:c.-51+27582C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs527578548" "This variant is a VUS because it does not have enough information."
490417 "chr21:35855855:T>G" "KCNE1" "NM_001270404:c.-51+27544A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs147106658" "This variant is a VUS because it does not have enough information." 0 1322 0 4 1006 0.004 0 694 0 0 1008 0 0 978 0 4 5008 0.000798722
490418 "chr21:35855866:G>C" "KCNE1" "NM_001270404:c.-51+27533C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs370596162" "This variant is a VUS because it does not have enough information."
490419 "chr21:35855871:C>-" "KCNE1" "NM_001270404:c.-51+27528delG" "FIVE_PRIME_INTRON" "Unknown significance" "rs780340531" "This variant is a VUS because it does not have enough information."
490420 "chr21:35855876:C>T" "KCNE1" "NM_001270404:c.-51+27523G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs373994664" "This variant is a VUS because it does not have enough information."
490421 "chr21:35855877:G>A" "KCNE1" "NM_001270404:c.-51+27522C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs559961071" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490422 "chr21:35855899:T>C" "KCNE1" "NM_001270404:c.-51+27500A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs529831855" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
490423 "chr21:35855906:C>A" "KCNE1" "NM_001270404:c.-51+27493G>T" "FIVE_PRIME_INTRON" "Benign" "rs138542329" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 35 1322 0.0265 0 1006 0 0 694 0 0 1008 0 0 978 0 35 5008 0.00698882
490424 "chr21:35855939:T>C" "KCNE1" "NM_001270404:c.-51+27460A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs756361999" "This variant is a VUS because it does not have enough information."
490425 "chr21:35855956:A>G" "KCNE1" "NM_001270404:c.-51+27443T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs534900364" "This variant is a VUS because it does not have enough information."
490426 "chr21:35855997:G>A" "KCNE1" "NM_001270404:c.-51+27402C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs569552136" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
490427 "chr21:35856004:G>A" "KCNE1" "NM_001270404:c.-51+27395C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs755110404" "This variant is a VUS because it does not have enough information."
490428 "chr21:35856015:T>A" "KCNE1" "NM_001270404:c.-51+27384A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs376288670" "This variant is a VUS because it does not have enough information."
490429 "chr21:35856033:->A" "KCNE1" "NM_001270404:c.-51+27366_-51+27367insT" "FIVE_PRIME_INTRON" "Benign" "rs555499384" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 403 1322 0.3048 0 1006 0 15 694 0.0216 55 1008 0.0546 93 978 0.0951 566 5008 0.113019
490430 "chr21:35856041:C>T" "KCNE1" "NM_001270404:c.-51+27358G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs779519904" "This variant is a VUS because it does not have enough information."
490431 "chr21:35856047:G>A" "KCNE1" "NM_001270404:c.-51+27352C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs748684682" "This variant is a VUS because it does not have enough information."
490432 "chr21:35856062:C>-" "KCNE1" "NM_001270404:c.-51+27337delG" "FIVE_PRIME_INTRON" "Benign" "rs148327825" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 71 1322 0.0537 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 72 5008 0.014377
490433 "chr21:35856117:A>G" "KCNE1" "NM_001270404:c.-51+27282T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs772540719" "This variant is a VUS because it does not have enough information."
490434 "chr21:35856119:A>G" "KCNE1" "NM_001270404:c.-51+27280T>C" "FIVE_PRIME_INTRON" "Benign" "rs546841407" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 0 1008 0 7 978 0.0072 7 5008 0.00139776
490435 "chr21:35856135:A>G" "KCNE1" "NM_001270404:c.-51+27264T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs552226362" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490436 "chr21:35856136:G>A" "KCNE1" "NM_001270404:c.-51+27263C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs570395815" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490437 "chr21:35856161:G>A" "KCNE1" "NM_001270404:c.-51+27238C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs193148811" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490438 "chr21:35856206:T>C" "KCNE1" "NM_001270404:c.-51+27193A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs746669514" "This variant is a VUS because it does not have enough information."
490439 "chr21:35856224:C>T" "KCNE1" "NM_001270404:c.-51+27175G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs571842308" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
490440 "chr21:35856225:G>A" "KCNE1" "NM_001270404:c.-51+27174C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs776352389" "This variant is a VUS because it does not have enough information."
490441 "chr21:35856236:T>C" "KCNE1" "NM_001270404:c.-51+27163A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs185648848" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490442 "chr21:35856281:G>T" "KCNE1" "NM_001270404:c.-51+27118C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs536355468" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490443 "chr21:35856313:C>T" "KCNE1" "NM_001270404:c.-51+27086G>A" "FIVE_PRIME_INTRON" "Benign" "rs73365344" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 291 1322 0.2201 46 1006 0.0457 56 694 0.0807 190 1008 0.1885 130 978 0.1329 713 5008 0.142372
490444 "chr21:35856322:G>T" "KCNE1" "NM_001270404:c.-51+27077C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs142319911" "This variant is a VUS because it does not have enough information." 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042
490445 "chr21:35856355:T>G" "KCNE1" "NM_001270404:c.-51+27044A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs188289191" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
490446 "chr21:35856380:T>C" "KCNE1" "NM_001270404:c.-51+27019A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs765522758" "This variant is a VUS because it does not have enough information."
490447 "chr21:35856383:C>A" "KCNE1" "NM_001270404:c.-51+27016G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs8126614" "This variant is a VUS because it does not have enough information."
490448 "chr21:35856384:G>C" "KCNE1" "NM_001270404:c.-51+27015C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs565606056" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
490449 "chr21:35856401:C>A" "KCNE1" "NM_001270404:c.-51+26998G>T" "FIVE_PRIME_INTRON" "Benign" "rs115115365" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 13 1322 0.0098 0 1006 0 0 694 0 0 1008 0 0 978 0 13 5008 0.00259585
490450 "chr21:35856402:G>A" "KCNE1" "NM_001270404:c.-51+26997C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs775387630" "This variant is a VUS because it does not have enough information."
490451 "chr21:35856409:C>G" "KCNE1" "NM_001270404:c.-51+26990G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs762920705" "This variant is a VUS because it does not have enough information."
490452 "chr21:35856427:C>T" "KCNE1" "NM_001270404:c.-51+26972G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs541714974" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
490453 "chr21:35856429:T>C" "KCNE1" "NM_001270404:c.-51+26970A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs575222556" "This variant is a VUS because it does not have enough information."
490454 "chr21:35856434:T>A" "KCNE1" "NM_001270404:c.-51+26965A>T" "FIVE_PRIME_INTRON" "Benign" "rs78330388" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 92 1322 0.0696 1 1006 0.001 4 694 0.0058 0 1008 0 0 978 0 97 5008 0.019369
490455 "chr21:35856442:T>C" "KCNE1" "NM_001270404:c.-51+26957A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs530269718" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490456 "chr21:35856448:C>A" "KCNE1" "NM_001270404:c.-51+26951G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs191195478" "This variant is a VUS because it does not have enough information."
490457 "chr21:35856488:C>T" "KCNE1" "NM_001270404:c.-51+26911G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs548024884" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490458 "chr21:35856504:C>T" "KCNE1" "NM_001270404:c.-51+26895G>A" "FIVE_PRIME_INTRON" "Benign" "rs2834494" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 10 1322 0.0076 64 1006 0.0636 51 694 0.0735 135 1008 0.1339 60 978 0.0613 320 5008 0.0638978
490459 "chr21:35856515:T>C" "KCNE1" "NM_001270404:c.-51+26884A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs554719167" "This variant is a VUS because it does not have enough information."
490460 "chr21:35856602:->A" "KCNE1" "NM_001270404:c.-51+26797_-51+26798insT" "FIVE_PRIME_INTRON" "Unknown significance" "rs756078667" "This variant is a VUS because it does not have enough information."
490461 "chr21:35856605:A>G" "KCNE1" "NM_001270404:c.-51+26794T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs530454800" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490462 "chr21:35856613:A>G" "KCNE1" "NM_001270404:c.-51+26786T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs552127515" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490463 "chr21:35856651:G>A" "KCNE1" "NM_001270404:c.-51+26748C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs570085941" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
490464 "chr21:35856668:A>G" "KCNE1" "NM_001270404:c.-51+26731T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs528383799" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 1 1006 0.001 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
490465 "chr21:35856679:A>T" "KCNE1" "NM_001270404:c.-51+26720T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs184072636" "This variant is a VUS because it does not have enough information."
490466 "chr21:35856737:T>A" "KCNE1" "NM_001270404:c.-51+26662A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs546447573" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490467 "chr21:35856762:A>C" "KCNE1" "NM_001270404:c.-51+26637T>G" "FIVE_PRIME_INTRON" "Benign" "rs16991720" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 282 1322 0.2133 0 1006 0 8 694 0.0115 37 1008 0.0367 54 978 0.0552 381 5008 0.0760783
490468 "chr21:35856891:C>G" "KCNE1" "NM_001270404:c.-51+26508G>C" "FIVE_PRIME_INTRON" "Benign" "rs61378747" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 46 1322 0.0348 64 1006 0.0636 51 694 0.0735 135 1008 0.1339 60 978 0.0613 356 5008 0.0710863
490469 "chr21:35856956:A>T" "KCNE1" "NM_001270404:c.-51+26443T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs755057276" "This variant is a VUS because it does not have enough information."
490470 "chr21:35856972:A>G" "KCNE1" "NM_001270404:c.-51+26427T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs188420445" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490471 "chr21:35856995:T>C" "KCNE1" "NM_001270404:c.-51+26404A>G" "FIVE_PRIME_INTRON" "Benign" "rs138749366" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 11 1322 0.0083 0 1006 0 0 694 0 0 1008 0 0 978 0 11 5008 0.00219649
490472 "chr21:35857052:G>C" "KCNE1" "NM_001270404:c.-51+26347C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs77734144" "This variant is a VUS because it does not have enough information."
490473 "chr21:35857052:G>T" "KCNE1" "NM_001270404:c.-51+26347C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs77734144" "This variant is a VUS because it does not have enough information."
490474 "chr21:35857056:A>G" "KCNE1" "NM_001270404:c.-51+26343T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs537123472" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490475 "chr21:35857059:G>A" "KCNE1" "NM_001270404:c.-51+26340C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs750999959" "This variant is a VUS because it does not have enough information."
490476 "chr21:35857090:G>A" "KCNE1" "NM_001270404:c.-51+26309C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs182021466" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
490477 "chr21:35857139:A>G" "KCNE1" "NM_001270404:c.-51+26260T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs112017622" "This variant is a VUS because it does not have enough information." 0 1322 0 3 1006 0.003 0 694 0 0 1008 0 2 978 0.002 5 5008 0.000998403
490478 "chr21:35857151:A>G" "KCNE1" "NM_001270404:c.-51+26248T>C" "FIVE_PRIME_INTRON" "Benign" "rs55866738" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 58 1322 0.0439 210 1006 0.2087 89 694 0.1282 2 1008 0.002 183 978 0.1871 542 5008 0.108227
490479 "chr21:35857193:G>T" "KCNE1" "NM_001270404:c.-51+26206C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs553697202" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490480 "chr21:35857195:T>-" "KCNE1" "NM_001270404:c.-51+26204delA" "FIVE_PRIME_INTRON" "Unknown significance" "rs748639861" "This variant is a VUS because it does not have enough information."
490481 "chr21:35857216:T>C" "KCNE1" "NM_001270404:c.-51+26183A>G" "FIVE_PRIME_INTRON" "Benign" "rs577047650" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 0 1008 0 7 978 0.0072 7 5008 0.00139776
490482 "chr21:35857272:T>C" "KCNE1" "NM_001270404:c.-51+26127A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs747271560" "This variant is a VUS because it does not have enough information."
490483 "chr21:35857296:A>G" "KCNE1" "NM_001270404:c.-51+26103T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs149370703" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490484 "chr21:35857305:G>T" "KCNE1" "NM_001270404:c.-51+26094C>A" "FIVE_PRIME_INTRON" "Benign" "rs56824655" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 328 1322 0.2481 64 1006 0.0636 59 694 0.085 190 1008 0.1885 153 978 0.1564 794 5008 0.158546
490485 "chr21:35857347:G>C" "KCNE1" "NM_001270404:c.-51+26052C>G" "FIVE_PRIME_INTRON" "Benign" "rs144752634" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 36 1322 0.0272 0 1006 0 0 694 0 0 1008 0 0 978 0 36 5008 0.0071885
490486 "chr21:35857357:G>A" "KCNE1" "NM_001270404:c.-51+26042C>T" "FIVE_PRIME_INTRON" "Benign" "rs117454769" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1 1322 0.0008 22 1006 0.0219 15 694 0.0216 0 1008 0 0 978 0 38 5008 0.00758786
490487 "chr21:35857374:C>T" "KCNE1" "NM_001270404:c.-51+26025G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs563746585" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490488 "chr21:35857394:T>A" "KCNE1" "NM_001270404:c.-51+26005A>T" "FIVE_PRIME_INTRON" "Benign" "rs76729782" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 282 1322 0.2133 0 1006 0 8 694 0.0115 55 1008 0.0546 94 978 0.0961 439 5008 0.0876597
490489 "chr21:35857466:C>A" "KCNE1" "NM_001270404:c.-51+25933G>T" "FIVE_PRIME_INTRON" "Benign" "rs8131587" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 62 1322 0.0469 0 1006 0 0 694 0 0 1008 0 0 978 0 62 5008 0.0123802
490490 "chr21:35857470:T>C" "KCNE1" "NM_001270404:c.-51+25929A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs769265631" "This variant is a VUS because it does not have enough information."
490491 "chr21:35857471:T>C" "KCNE1" "NM_001270404:c.-51+25928A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs148025827" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490492 "chr21:35857505:C>T" "KCNE1" "NM_001270404:c.-51+25894G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs775051967" "This variant is a VUS because it does not have enough information."
490493 "chr21:35857511:A>G" "KCNE1" "NM_001270404:c.-51+25888T>C" "FIVE_PRIME_INTRON" "Benign" "rs8131590" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 62 1322 0.0469 0 1006 0 0 694 0 0 1008 0 0 978 0 62 5008 0.0123802
490494 "chr21:35857528:T>A" "KCNE1" "NM_001270404:c.-51+25871A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs779982314" "This variant is a VUS because it does not have enough information."
490495 "chr21:35857543:T>C" "KCNE1" "NM_001270404:c.-51+25856A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs550774160" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490496 "chr21:35857565:T>C" "KCNE1" "NM_001270404:c.-51+25834A>G" "FIVE_PRIME_INTRON" "Benign" "rs115606902" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 49 1322 0.0371 0 1006 0 3 694 0.0043 0 1008 0 0 978 0 52 5008 0.0103834
490497 "chr21:35857581:G>A" "KCNE1" "NM_001270404:c.-51+25818C>T" "FIVE_PRIME_INTRON" "Benign" "rs118173420" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 18 1008 0.0179 39 978 0.0399 57 5008 0.0113818
490498 "chr21:35857589:C>T" "KCNE1" "NM_001270404:c.-51+25810G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs367966253" "This variant is a VUS because it does not have enough information."
490499 "chr21:35857594:G>A" "KCNE1" "NM_001270404:c.-51+25805C>T" "FIVE_PRIME_INTRON" "Benign" "rs16991721" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 286 1322 0.2163 0 1006 0 8 694 0.0115 37 1008 0.0367 55 978 0.0562 386 5008 0.0770767
490500 "chr21:35857603:G>C" "KCNE1" "NM_001270404:c.-51+25796C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs761472242" "This variant is a VUS because it does not have enough information."
490501 "chr21:35857617:G>A" "KCNE1" "NM_001270404:c.-51+25782C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs142587058" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490502 "chr21:35857654:C>T" "KCNE1" "NM_001270404:c.-51+25745G>A" "FIVE_PRIME_INTRON" "Benign" "rs79580988" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 46 1322 0.0348 0 1006 0 0 694 0 0 1008 0 0 978 0 46 5008 0.0091853
490503 "chr21:35857655:T>C" "KCNE1" "NM_001270404:c.-51+25744A>G" "FIVE_PRIME_INTRON" "Benign" "rs78988245" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 68 1322 0.0514 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 69 5008 0.013778
490504 "chr21:35857657:G>C" "KCNE1" "NM_001270404:c.-51+25742C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs549027880" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
490505 "chr21:35857662:T>G" "KCNE1" "NM_001270404:c.-51+25737A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs561052406" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490506 "chr21:35857687:G>A" "KCNE1" "NM_001270404:c.-51+25712C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs557544782" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490507 "chr21:35857694:G>A" "KCNE1" "NM_001270404:c.-51+25705C>T" "FIVE_PRIME_INTRON" "Benign" "rs575708832" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 0 1008 0 17 978 0.0174 17 5008 0.00339457
490508 "chr21:35857700:T>C" "KCNE1" "NM_001270404:c.-51+25699A>G" "FIVE_PRIME_INTRON" "Benign" "rs4817659" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 973 1322 0.736 626 1006 0.6223 354 694 0.5101 429 1008 0.4256 556 978 0.5685 2938 5008 0.586661
490509 "chr21:35857704:A>G" "KCNE1" "NM_001270404:c.-51+25695T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs772393844" "This variant is a VUS because it does not have enough information."
490510 "chr21:35857717:C>T" "KCNE1" "NM_001270404:c.-51+25682G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs563829757" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 3 978 0.0031 4 5008 0.000798722
490511 "chr21:35857750:T>G" "KCNE1" "NM_001270404:c.-51+25649A>C" "FIVE_PRIME_INTRON" "Benign" "rs4817660" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 332 1322 0.2511 64 1006 0.0636 59 694 0.085 190 1008 0.1885 147 978 0.1503 792 5008 0.158147
490512 "chr21:35857755:C>T" "KCNE1" "NM_001270404:c.-51+25644G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs539821100" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490513 "chr21:35857756:G>A" "KCNE1" "NM_001270404:c.-51+25643C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs561499476" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490514 "chr21:35857811:A>T" "KCNE1" "NM_001270404:c.-51+25588T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs760832037" "This variant is a VUS because it does not have enough information."
490515 "chr21:35857822:T>C" "KCNE1" "NM_001270404:c.-51+25577A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs752130462" "This variant is a VUS because it does not have enough information."
490516 "chr21:35857843:C>A" "KCNE1" "NM_001270404:c.-51+25556G>T" "FIVE_PRIME_INTRON" "Benign" "rs139976984" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 124 1322 0.0938 0 1006 0 9 694 0.013 0 1008 0 0 978 0 133 5008 0.0265575
490517 "chr21:35857949:G>A" "KCNE1" "NM_001270404:c.-51+25450C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs76354223" "This variant is a VUS because it does not have enough information." 6 1322 0.0045 0 1006 0 0 694 0 0 1008 0 0 978 0 6 5008 0.00119808
490518 "chr21:35857987:->A" "KCNE1" "NM_001270404:c.-51+25412_-51+25413insT" "FIVE_PRIME_INTRON" "Unknown significance" "rs547871168" "This variant is a VUS because it does not have enough information."
490519 "chr21:35858097:G>A" "KCNE1" "NM_001270404:c.-51+25302C>T" "FIVE_PRIME_INTRON" "Benign" "rs2211698" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 562 1322 0.4251 64 1006 0.0636 75 694 0.1081 190 1008 0.1885 153 978 0.1564 1044 5008 0.208466
490520 "chr21:35858120:C>A" "KCNE1" "NM_001270404:c.-51+25279G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs776581594" "This variant is a VUS because it does not have enough information."
490521 "chr21:35858141:C>T" "KCNE1" "NM_001270404:c.-51+25258G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs538939037" "This variant is a VUS because it does not have enough information."
490522 "chr21:35858142:G>A" "KCNE1" "NM_001270404:c.-51+25257C>T" "FIVE_PRIME_INTRON" "Benign" "rs146181940" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 6 1008 0.006 0 978 0 6 5008 0.00119808
490523 "chr21:35858156:C>G" "KCNE1" "NM_001270404:c.-51+25243G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs781579970" "This variant is a VUS because it does not have enough information."
490524 "chr21:35858176:->C" "KCNE1" "NM_001270404:c.-51+25223_-51+25224insG" "FIVE_PRIME_INTRON" "Unknown significance" "rs34234994" "This variant is a VUS because it does not have enough information."
490525 "chr21:35858176:C>T" "KCNE1" "NM_001270404:c.-51+25223G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs560957561" "This variant is a VUS because it does not have enough information."
490526 "chr21:35858233:T>C" "KCNE1" "NM_001270404:c.-51+25166A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs760034852" "This variant is a VUS because it does not have enough information."
490527 "chr21:35858269:A>C" "KCNE1" "NM_001270404:c.-51+25130T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs765786319" "This variant is a VUS because it does not have enough information."
490528 "chr21:35858281:C>T" "KCNE1" "NM_001270404:c.-51+25118G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs552742211" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490529 "chr21:35858324:C>G" "KCNE1" "NM_001270404:c.-51+25075G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs745518097" "This variant is a VUS because it does not have enough information."
490530 "chr21:35858355:G>C" "KCNE1" "NM_001270404:c.-51+25044C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs755826265" "This variant is a VUS because it does not have enough information."
490531 "chr21:35858399:G>A" "KCNE1" "NM_001270404:c.-51+25000C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs570938942" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
490532 "chr21:35858405:A>G" "KCNE1" "NM_001270404:c.-51+24994T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs535044491" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490533 "chr21:35858410:T>C" "KCNE1" "NM_001270404:c.-51+24989A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs73365350" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490534 "chr21:35858439:C>A" "KCNE1" "NM_001270404:c.-51+24960G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs375262022" "This variant is a VUS because it does not have enough information."
490535 "chr21:35858490:A>G" "KCNE1" "NM_001270404:c.-51+24909T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs568328056" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490536 "chr21:35858491:G>A" "KCNE1" "NM_001270404:c.-51+24908C>T" "FIVE_PRIME_INTRON" "Benign" "rs536154844" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 0 1008 0 11 978 0.0112 11 5008 0.00219649
490537 "chr21:35858502:A>C" "KCNE1" "NM_001270404:c.-51+24897T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs557323819" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490538 "chr21:35858504:C>A" "KCNE1" "NM_001270404:c.-51+24895G>T" "FIVE_PRIME_INTRON" "Benign" "rs190240762" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 10 1322 0.0076 0 1006 0 0 694 0 0 1008 0 0 978 0 10 5008 0.00199681
490539 "chr21:35858519:G>C" "KCNE1" "NM_001270404:c.-51+24880C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs182244094" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490540 "chr21:35858545:C>G" "KCNE1" "NM_001270404:c.-51+24854G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs753052391" "This variant is a VUS because it does not have enough information."
490541 "chr21:35858547:T>A" "KCNE1" "NM_001270404:c.-51+24852A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs557459366" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 2 5008 0.000399361
490542 "chr21:35858571:T>C" "KCNE1" "NM_001270404:c.-51+24828A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs544137692" "This variant is a VUS because it does not have enough information."
490543 "chr21:35858649:C>T" "KCNE1" "NM_001270404:c.-51+24750G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs564018968" "This variant is a VUS because it does not have enough information."
490544 "chr21:35858654:G>C" "KCNE1" "NM_001270404:c.-51+24745C>G" "FIVE_PRIME_INTRON" "Benign" "rs2834495" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 397 1322 0.3003 0 1006 0 17 694 0.0245 37 1008 0.0367 55 978 0.0562 506 5008 0.101038
490545 "chr21:35858656:T>C" "KCNE1" "NM_001270404:c.-51+24743A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs186359472" "This variant is a VUS because it does not have enough information." 0 1322 0 2 1006 0.002 0 694 0 0 1008 0 2 978 0.002 4 5008 0.000798722
490546 "chr21:35858675:T>A" "KCNE1" "NM_001270404:c.-51+24724A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs561734835" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490547 "chr21:35858725:G>T" "KCNE1" "NM_001270404:c.-51+24674C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs139055055" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
490548 "chr21:35858734:G>A" "KCNE1" "NM_001270404:c.-51+24665C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs768240228" "This variant is a VUS because it does not have enough information."
490549 "chr21:35858779:T>C" "KCNE1" "NM_001270404:c.-51+24620A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs778663542" "This variant is a VUS because it does not have enough information."
490550 "chr21:35858818:C>T" "KCNE1" "NM_001270404:c.-51+24581G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs536262137" "This variant is a VUS because it does not have enough information."
490551 "chr21:35858860:G>A" "KCNE1" "NM_001270404:c.-51+24539C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs149895666" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490552 "chr21:35858892:A>G" "KCNE1" "NM_001270404:c.-51+24507T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs763711522" "This variant is a VUS because it does not have enough information."
490553 "chr21:35858895:CT>-" "KCNE1" "NM_001270404:c.-51+24504_-51+24507delAG" "FIVE_PRIME_INTRON" "Unknown significance" "rs751173486" "This variant is a VUS because it does not have enough information."
490554 "chr21:35858898:T>C" "KCNE1" "NM_001270404:c.-51+24501A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs144958643" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490555 "chr21:35858905:C>T" "KCNE1" "NM_001270404:c.-51+24494G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs148968720" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
490556 "chr21:35858921:G>A" "KCNE1" "NM_001270404:c.-51+24478C>T" "FIVE_PRIME_INTRON" "Benign" "rs73365353" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 280 1322 0.2118 0 1006 0 8 694 0.0115 37 1008 0.0367 55 978 0.0562 380 5008 0.0758786
490557 "chr21:35858921:G>C" "KCNE1" "NM_001270404:c.-51+24478C>G" "FIVE_PRIME_INTRON" "Benign" "rs73365353" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 9 1322 0.0068 0 1006 0 0 694 0 0 1008 0 0 978 0 9 5008 0.00179712
490558 "chr21:35859006:C>T" "KCNE1" "NM_001270404:c.-51+24393G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs773207334" "This variant is a VUS because it does not have enough information."
490559 "chr21:35859014:C>T" "KCNE1" "NM_001270404:c.-51+24385G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs145562384" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490560 "chr21:35859064:C>T" "KCNE1" "NM_001270404:c.-51+24335G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs532229505" "This variant is a VUS because it does not have enough information."
490561 "chr21:35859065:C>T" "KCNE1" "NM_001270404:c.-51+24334G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs546737089" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490562 "chr21:35859095:C>T" "KCNE1" "NM_001270404:c.-51+24304G>A" "FIVE_PRIME_INTRON" "Benign" "rs147729445" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 4 1006 0.004 0 694 0 5 1008 0.005 1 978 0.001 10 5008 0.00199681
490563 "chr21:35859113:T>G" "KCNE1" "NM_001270404:c.-51+24286A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs535477448" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 2 978 0.002 2 5008 0.000399361
490564 "chr21:35859185:T>C" "KCNE1" "NM_001270404:c.-51+24214A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs759819050" "This variant is a VUS because it does not have enough information."
490565 "chr21:35859213:G>A" "KCNE1" "NM_001270404:c.-51+24186C>T" "FIVE_PRIME_INTRON" "Benign" "rs114651594" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 115 1322 0.087 0 1006 0 9 694 0.013 0 1008 0 0 978 0 124 5008 0.0247604
490566 "chr21:35859242:C>T" "KCNE1" "NM_001270404:c.-51+24157G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs569185653" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490567 "chr21:35859245:A>G" "KCNE1" "NM_001270404:c.-51+24154T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs539718116" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490568 "chr21:35859257:C>A" "KCNE1" "NM_001270404:c.-51+24142G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs557946129" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490569 "chr21:35859258:A>G" "KCNE1" "NM_001270404:c.-51+24141T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs756888827" "This variant is a VUS because it does not have enough information."
490570 "chr21:35859262:T>G" "KCNE1" "NM_001270404:c.-51+24137A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs770074976" "This variant is a VUS because it does not have enough information."
490571 "chr21:35859283:C>T" "KCNE1" "NM_001270404:c.-51+24116G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs142632574" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 2 978 0.002 4 5008 0.000798722
490572 "chr21:35859283:C>A" "KCNE1" "NM_001270404:c.-51+24116G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs142632574" "This variant is a VUS because it does not have enough information."
490573 "chr21:35859283:C>G" "KCNE1" "NM_001270404:c.-51+24116G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs142632574" "This variant is a VUS because it does not have enough information."
490574 "chr21:35859284:G>A" "KCNE1" "NM_001270404:c.-51+24115C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs533646453" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
490575 "chr21:35859292:A>G" "KCNE1" "NM_001270404:c.-51+24107T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs189927001" "This variant is a VUS because it does not have enough information." 0 1322 0 2 1006 0.002 1 694 0.0014 0 1008 0 0 978 0 3 5008 0.000599042
490576 "chr21:35859303:C>G" "KCNE1" "NM_001270404:c.-51+24096G>C" "FIVE_PRIME_INTRON" "Benign" "rs116939138" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 18 1008 0.0179 39 978 0.0399 57 5008 0.0113818
490577 "chr21:35859304:C>T" "KCNE1" "NM_001270404:c.-51+24095G>A" "FIVE_PRIME_INTRON" "Benign" "rs115220031" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 38 1322 0.0287 0 1006 0 3 694 0.0043 0 1008 0 0 978 0 41 5008 0.0081869
490578 "chr21:35859334:->T" "KCNE1" "NM_001270404:c.-51+24065_-51+24066insA" "FIVE_PRIME_INTRON" "Unknown significance" "rs781339461" "This variant is a VUS because it does not have enough information."
490579 "chr21:35859338:T>C" "KCNE1" "NM_001270404:c.-51+24061A>G" "FIVE_PRIME_INTRON" "Benign" "rs146911203" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 4 1322 0.003 0 1006 0 0 694 0 18 1008 0.0179 39 978 0.0399 61 5008 0.0121805
490580 "chr21:35859341:T>A" "KCNE1" "NM_001270404:c.-51+24058A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs578013679" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490581 "chr21:35859344:T>A" "KCNE1" "NM_001270404:c.-51+24055A>T" "FIVE_PRIME_INTRON" "Benign" "rs545287847" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 40 1322 0.0303 0 1006 0 0 694 0 37 1008 0.0367 55 978 0.0562 132 5008 0.0263578
490582 "chr21:35859345:T>A" "KCNE1" "NM_001270404:c.-51+24054A>T" "FIVE_PRIME_INTRON" "Benign" "rs577268801" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 189 1322 0.143 0 1006 0 6 694 0.0086 37 1008 0.0367 55 978 0.0562 287 5008 0.0573083
490583 "chr21:35859346:T>A" "KCNE1" "NM_001270404:c.-51+24053A>T" "FIVE_PRIME_INTRON" "Benign" "rs114898934" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 279 1322 0.211 1 1006 0.001 8 694 0.0115 37 1008 0.0367 56 978 0.0573 381 5008 0.0760783
490584 "chr21:35859355:TATG>-" "KCNE1" "NM_001270404:c.-51+24044_-51+24049delCATA" "FIVE_PRIME_INTRON" "Unknown significance" "rs370801293" "This variant is a VUS because it does not have enough information."
490585 "chr21:35859391:C>A" "KCNE1" "NM_001270404:c.-51+24008G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs148295547" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490586 "chr21:35859432:G>C" "KCNE1" "NM_001270404:c.-51+23967C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs756117350" "This variant is a VUS because it does not have enough information."
490587 "chr21:35859458:T>A" "KCNE1" "NM_001270404:c.-51+23941A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs570313487" "This variant is a VUS because it does not have enough information."
490588 "chr21:35859488:G>A" "KCNE1" "NM_001270404:c.-51+23911C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs562032395" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490589 "chr21:35859493:T>C" "KCNE1" "NM_001270404:c.-51+23906A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs185733439" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
490590 "chr21:35859501:C>T" "KCNE1" "NM_001270404:c.-51+23898G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs550720233" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
490591 "chr21:35859518:G>A" "KCNE1" "NM_001270404:c.-51+23881C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs140455480" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490592 "chr21:35859556:T>G" "KCNE1" "NM_001270404:c.-51+23843A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs190986086" "This variant is a VUS because it does not have enough information."
490593 "chr21:35859564:C>T" "KCNE1" "NM_001270404:c.-51+23835G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs150422117" "This variant is a VUS because it does not have enough information." 0 1322 0 4 1006 0.004 2 694 0.0029 0 1008 0 0 978 0 6 5008 0.00119808
490594 "chr21:35859571:T>C" "KCNE1" "NM_001270404:c.-51+23828A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs551614524" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 1 978 0.001 2 5008 0.000399361
490595 "chr21:35859639:C>T" "KCNE1" "NM_001270404:c.-51+23760G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs750724849" "This variant is a VUS because it does not have enough information."
490596 "chr21:35859640:G>A" "KCNE1" "NM_001270404:c.-51+23759C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs756479065" "This variant is a VUS because it does not have enough information."
490597 "chr21:35859651:G>A" "KCNE1" "NM_001270404:c.-51+23748C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs566772567" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490598 "chr21:35859668:G>A" "KCNE1" "NM_001270404:c.-51+23731C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs534123969" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
490599 "chr21:35859681:->GTTG" "KCNE1" "NM_001270404:c.-51+23718_-51+23719insCAAC" "FIVE_PRIME_INTRON" "Unknown significance" "rs773593240" "This variant is a VUS because it does not have enough information."
490600 "chr21:35859707:G>A" "KCNE1" "NM_001270404:c.-51+23692C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs183261571" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
490601 "chr21:35859726:G>A" "KCNE1" "NM_001270404:c.-51+23673C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs376157881" "This variant is a VUS because it does not have enough information."
490602 "chr21:35859730:C>T" "KCNE1" "NM_001270404:c.-51+23669G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs567225744" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490603 "chr21:35859742:G>A" "KCNE1" "NM_001270404:c.-51+23657C>T" "FIVE_PRIME_INTRON" "Benign" "rs138221160" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 116 1322 0.0877 0 1006 0 9 694 0.013 0 1008 0 0 978 0 125 5008 0.0249601
490604 "chr21:35859783:G>A" "KCNE1" "NM_001270404:c.-51+23616C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs539838405" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490605 "chr21:35859812:T>C" "KCNE1" "NM_001270404:c.-51+23587A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs577668804" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
490606 "chr21:35859822:A>C" "KCNE1" "NM_001270404:c.-51+23577T>G" "FIVE_PRIME_INTRON" "Benign" "rs2898206" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 208 1322 0.1573 0 1006 0 15 694 0.0216 1 1008 0.001 0 978 0 224 5008 0.0447284
490607 "chr21:35859847:T>C" "KCNE1" "NM_001270404:c.-51+23552A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs371404966" "This variant is a VUS because it does not have enough information."
490608 "chr21:35859872:A>G" "KCNE1" "NM_001270404:c.-51+23527T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs560055810" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490609 "chr21:35859890:A>C" "KCNE1" "NM_001270404:c.-51+23509T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs188537989" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 2 978 0.002 3 5008 0.000599042
490610 "chr21:35859900:T>C" "KCNE1" "NM_001270404:c.-51+23499A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs542435890" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 3 1008 0.003 0 978 0 3 5008 0.000599042
490611 "chr21:35859923:T>C" "KCNE1" "NM_001270404:c.-51+23476A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs754426308" "This variant is a VUS because it does not have enough information."
490612 "chr21:35859941:G>C" "KCNE1" "NM_001270404:c.-51+23458C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs778527119" "This variant is a VUS because it does not have enough information."
490613 "chr21:35859963:G>A" "KCNE1" "NM_001270404:c.-51+23436C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs747191300" "This variant is a VUS because it does not have enough information."
490614 "chr21:35859979:G>C" "KCNE1" "NM_001270404:c.-51+23420C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs561109069" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490615 "chr21:35860003:A>G" "KCNE1" "NM_001270404:c.-51+23396T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs529385694" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490616 "chr21:35860004:A>G" "KCNE1" "NM_001270404:c.-51+23395T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs748032181" "This variant is a VUS because it does not have enough information."
490617 "chr21:35860076:G>A" "KCNE1" "NM_001270404:c.-51+23323C>T" "FIVE_PRIME_INTRON" "Benign" "rs80166167" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 18 1006 0.0179 9 694 0.013 0 1008 0 1 978 0.001 28 5008 0.00559105
490618 "chr21:35860082:A>T" "KCNE1" "NM_001270404:c.-51+23317T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs777866343" "This variant is a VUS because it does not have enough information."
490619 "chr21:35860119:C>T" "KCNE1" "NM_001270404:c.-51+23280G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs562548566" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490620 "chr21:35860131:G>A" "KCNE1" "NM_001270404:c.-51+23268C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs533153470" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
490621 "chr21:35860182:G>C" "KCNE1" "NM_001270404:c.-51+23217C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs746760935" "This variant is a VUS because it does not have enough information."
490622 "chr21:35860187:C>T" "KCNE1" "NM_001270404:c.-51+23212G>A" "FIVE_PRIME_INTRON" "Benign" "rs4817661" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 9 1322 0.0068 63 1006 0.0626 50 694 0.072 136 1008 0.1349 59 978 0.0603 317 5008 0.0632987
490623 "chr21:35860209:A>C" "KCNE1" "NM_001270404:c.-51+23190T>G" "FIVE_PRIME_INTRON" "Benign" "rs193078685" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 7 1322 0.0053 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 8 5008 0.00159744
490624 "chr21:35860237:C>T" "KCNE1" "NM_001270404:c.-51+23162G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs368342055" "This variant is a VUS because it does not have enough information."
490625 "chr21:35860268:T>C" "KCNE1" "NM_001270404:c.-51+23131A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs745998233" "This variant is a VUS because it does not have enough information."
490626 "chr21:35860280:C>A" "KCNE1" "NM_001270404:c.-51+23119G>T" "FIVE_PRIME_INTRON" "Benign" "rs79401979" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 38 1322 0.0287 0 1006 0 3 694 0.0043 0 1008 0 0 978 0 41 5008 0.0081869
490627 "chr21:35860329:A>G" "KCNE1" "NM_001270404:c.-51+23070T>C" "FIVE_PRIME_INTRON" "Benign" "rs8128798" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 47 1322 0.0356 0 1006 0 3 694 0.0043 0 1008 0 0 978 0 50 5008 0.00998403
490628 "chr21:35860334:G>A" "KCNE1" "NM_001270404:c.-51+23065C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs775552172" "This variant is a VUS because it does not have enough information."
490629 "chr21:35860407:A>G" "KCNE1" "NM_001270404:c.-51+22992T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs544147030" "This variant is a VUS because it does not have enough information."
490630 "chr21:35860437:A>G" "KCNE1" "NM_001270404:c.-51+22962T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs776023510" "This variant is a VUS because it does not have enough information."
490631 "chr21:35860483:C>T" "KCNE1" "NM_001270404:c.-51+22916G>A" "FIVE_PRIME_INTRON" "Benign" "rs16991728" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 116 1322 0.0877 0 1006 0 9 694 0.013 0 1008 0 0 978 0 125 5008 0.0249601
490632 "chr21:35860519:T>C" "KCNE1" "NM_001270404:c.-51+22880A>G" "FIVE_PRIME_INTRON" "Benign" "rs2834496" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 580 1322 0.4387 63 1006 0.0626 72 694 0.1037 191 1008 0.1895 153 978 0.1564 1059 5008 0.211462
490633 "chr21:35860519:TG>CA" "KCNE1" "Unknown significance" "rs386818153" "This variant is a VUS because it does not have enough information."
490634 "chr21:35860520:G>A" "KCNE1" "NM_001270404:c.-51+22879C>T" "FIVE_PRIME_INTRON" "Benign" "rs56725857" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 309 1322 0.2337 0 1006 0 8 694 0.0115 37 1008 0.0367 55 978 0.0562 409 5008 0.0816693
490635 "chr21:35860540:G>A" "KCNE1" "NM_001270404:c.-51+22859C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs761807757" "This variant is a VUS because it does not have enough information."
490636 "chr21:35860555:G>A" "KCNE1" "NM_001270404:c.-51+22844C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs767940646" "This variant is a VUS because it does not have enough information."
490637 "chr21:35860564:G>A" "KCNE1" "NM_001270404:c.-51+22835C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs575194617" "This variant is a VUS because it does not have enough information."
490638 "chr21:35860590:G>A" "KCNE1" "NM_001270404:c.-51+22809C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs571309612" "This variant is a VUS because it does not have enough information." 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042
490639 "chr21:35860593:G>A" "KCNE1" "NM_001270404:c.-51+22806C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs8129498" "This variant is a VUS because it does not have enough information."
490640 "chr21:35860616:T>C" "KCNE1" "NM_001270404:c.-51+22783A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs538628724" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 2 1006 0.002 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042
490641 "chr21:35860627:G>A" "KCNE1" "NM_001270404:c.-51+22772C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs369333645" "This variant is a VUS because it does not have enough information."
490642 "chr21:35860639:A>G" "KCNE1" "NM_001270404:c.-51+22760T>C" "FIVE_PRIME_INTRON" "Benign" "rs115452607" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 13 1322 0.0098 0 1006 0 0 694 0 0 1008 0 0 978 0 13 5008 0.00259585
490643 "chr21:35860650:C>T" "KCNE1" "NM_001270404:c.-51+22749G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs572273002" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 3 1008 0.003 0 978 0 5 5008 0.000998403
490644 "chr21:35860651:G>A" "KCNE1" "NM_001270404:c.-51+22748C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs542387856" "This variant is a VUS because it does not have enough information."
490645 "chr21:35860652:T>C" "KCNE1" "NM_001270404:c.-51+22747A>G" "FIVE_PRIME_INTRON" "Benign" "rs61646055" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 42 1322 0.0318 63 1006 0.0626 50 694 0.072 136 1008 0.1349 59 978 0.0603 350 5008 0.0698882
490646 "chr21:35860657:C>T" "KCNE1" "NM_001270404:c.-51+22742G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs554478074" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490647 "chr21:35860658:G>A" "KCNE1" "NM_001270404:c.-51+22741C>T" "FIVE_PRIME_INTRON" "Benign" "rs17399476" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 218 1322 0.1649 0 1006 0 6 694 0.0086 38 1008 0.0377 55 978 0.0562 317 5008 0.0632987
490648 "chr21:35860665:C>T" "KCNE1" "NM_001270404:c.-51+22734G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs544348307" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490649 "chr21:35860670:C>T" "KCNE1" "NM_001270404:c.-51+22729G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs761471552" "This variant is a VUS because it does not have enough information."
490650 "chr21:35860674:C>A" "KCNE1" "NM_001270404:c.-51+22725G>T" "FIVE_PRIME_INTRON" "Benign" "rs145997059" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 1 1006 0.001 0 694 0 18 1008 0.0179 39 978 0.0399 58 5008 0.0115815
490651 "chr21:35860674:C>T" "KCNE1" "NM_001270404:c.-51+22725G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs145997059" "This variant is a VUS because it does not have enough information."
490652 "chr21:35860675:G>A" "KCNE1" "NM_001270404:c.-51+22724C>T" "FIVE_PRIME_INTRON" "Benign" "rs117930818" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 60 1008 0.0595 2 978 0.002 62 5008 0.0123802
490653 "chr21:35860738:G>A" "KCNE1" "NM_001270404:c.-51+22661C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs544982149" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490654 "chr21:35860798:C>A" "KCNE1" "NM_001270404:c.-51+22601G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs754727853" "This variant is a VUS because it does not have enough information."
490655 "chr21:35860833:C>G" "KCNE1" "NM_001270404:c.-51+22566G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs369121626" "This variant is a VUS because it does not have enough information."
490656 "chr21:35860837:->T" "KCNE1" "NM_001270404:c.-51+22562_-51+22563insA" "FIVE_PRIME_INTRON" "Unknown significance" "rs369041648" "This variant is a VUS because it does not have enough information."
490657 "chr21:35860874:G>C" "KCNE1" "NM_001270404:c.-51+22525C>G" "FIVE_PRIME_INTRON" "Benign" "rs138721940" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 9 1008 0.0089 0 978 0 9 5008 0.00179712
490658 "chr21:35860886:C>T" "KCNE1" "NM_001270404:c.-51+22513G>A" "FIVE_PRIME_INTRON" "Benign" "rs58627004" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 237 1322 0.1793 0 1006 0 7 694 0.0101 37 1008 0.0367 55 978 0.0562 336 5008 0.0670927
490659 "chr21:35860914:G>A" "KCNE1" "NM_001270404:c.-51+22485C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs141829119" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490660 "chr21:35860930:G>C" "KCNE1" "NM_001270404:c.-51+22469C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs547488105" "This variant is a VUS because it does not have enough information."
490661 "chr21:35860944:A>T" "KCNE1" "NM_001270404:c.-51+22455T>A" "FIVE_PRIME_INTRON" "Benign" "rs58518943" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 42 1322 0.0318 63 1006 0.0626 50 694 0.072 136 1008 0.1349 59 978 0.0603 350 5008 0.0698882
490662 "chr21:35860995:G>A" "KCNE1" "NM_001270404:c.-51+22404C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs531928892" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490663 "chr21:35860996:C>T" "KCNE1" "NM_001270404:c.-51+22403G>A" "FIVE_PRIME_INTRON" "Benign" "rs115126048" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 70 1322 0.053 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 71 5008 0.0141773
490664 "chr21:35861026:G>T" "KCNE1" "NM_001270404:c.-51+22373C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs758013701" "This variant is a VUS because it does not have enough information."
490665 "chr21:35861092:->T" "KCNE1" "NM_001270404:c.-51+22307_-51+22308insA" "FIVE_PRIME_INTRON" "Unknown significance" "rs375982339" "This variant is a VUS because it does not have enough information."
490666 "chr21:35861128:G>A" "KCNE1" "NM_001270404:c.-51+22271C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs571348168" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490667 "chr21:35861130:A>G" "KCNE1" "NM_001270404:c.-51+22269T>C" "FIVE_PRIME_INTRON" "Benign" "rs56665940" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 42 1322 0.0318 63 1006 0.0626 50 694 0.072 136 1008 0.1349 59 978 0.0603 350 5008 0.0698882
490668 "chr21:35861137:T>C" "KCNE1" "NM_001270404:c.-51+22262A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs547433040" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490669 "chr21:35861172:G>A" "KCNE1" "NM_001270404:c.-51+22227C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs548756297" "This variant is a VUS because it does not have enough information."
490670 "chr21:35861181:G>C" "KCNE1" "NM_001270404:c.-51+22218C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs755735826" "This variant is a VUS because it does not have enough information."
490671 "chr21:35861190:C>T" "KCNE1" "NM_001270404:c.-51+22209G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs202205941" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490672 "chr21:35861232:T>G" "KCNE1" "NM_001270404:c.-51+22167A>C" "FIVE_PRIME_INTRON" "Benign" "rs144625361" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 7 1322 0.0053 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 8 5008 0.00159744
490673 "chr21:35861236:C>T" "KCNE1" "NM_001270404:c.-51+22163G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs371163602" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490674 "chr21:35861237:G>A" "KCNE1" "NM_001270404:c.-51+22162C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs576200092" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490675 "chr21:35861241:C>T" "KCNE1" "NM_001270404:c.-51+22158G>A" "FIVE_PRIME_INTRON" "Benign" "rs76272713" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 39 1322 0.0295 63 1006 0.0626 50 694 0.072 138 1008 0.1369 98 978 0.1002 388 5008 0.077476
490676 "chr21:35861261:G>A" "KCNE1" "NM_001270404:c.-51+22138C>T" "FIVE_PRIME_INTRON" "Benign" "rs114687762" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 35 1322 0.0265 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 37 5008 0.00738818
490677 "chr21:35861273:A>G" "KCNE1" "NM_001270404:c.-51+22126T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs577733734" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490678 "chr21:35861288:A>-" "KCNE1" "NM_001270404:c.-51+22111delT" "FIVE_PRIME_INTRON" "Unknown significance" "rs113990637" "This variant is a VUS because it does not have enough information."
490679 "chr21:35861294:A>G" "KCNE1" "NM_001270404:c.-51+22105T>C" "FIVE_PRIME_INTRON" "Benign" "rs183388423" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 6 694 0.0086 0 1008 0 0 978 0 6 5008 0.00119808
490680 "chr21:35861298:A>G" "KCNE1" "NM_001270404:c.-51+22101T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs560293076" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
490681 "chr21:35861341:T>C" "KCNE1" "NM_001270404:c.-51+22058A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs530458521" "This variant is a VUS because it does not have enough information."
490682 "chr21:35861366:G>A" "KCNE1" "NM_001270404:c.-51+22033C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs757085749" "This variant is a VUS because it does not have enough information."
490683 "chr21:35861379:G>A" "KCNE1" "NM_001270404:c.-51+22020C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs781105917" "This variant is a VUS because it does not have enough information."
490684 "chr21:35861398:G>A" "KCNE1" "NM_001270404:c.-51+22001C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs187641362" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
490685 "chr21:35861415:C>T" "KCNE1" "NM_001270404:c.-51+21984G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs542996373" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490686 "chr21:35861425:C>A" "KCNE1" "NM_001270404:c.-51+21974G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs749455493" "This variant is a VUS because it does not have enough information."
490687 "chr21:35861426:T>C" "KCNE1" "NM_001270404:c.-51+21973A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs57492143" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490688 "chr21:35861484:A>G" "KCNE1" "NM_001270404:c.-51+21915T>C" "FIVE_PRIME_INTRON" "Benign" "rs115257618" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 80 1322 0.0605 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 81 5008 0.0161741
490689 "chr21:35861487:A>G" "KCNE1" "NM_001270404:c.-51+21912T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs768861499" "This variant is a VUS because it does not have enough information."
490690 "chr21:35861490:G>A" "KCNE1" "NM_001270404:c.-51+21909C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs774436901" "This variant is a VUS because it does not have enough information."
490691 "chr21:35861560:C>T" "KCNE1" "NM_001270404:c.-51+21839G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs79929895" "This variant is a VUS because it does not have enough information."
490692 "chr21:35861571:C>G" "KCNE1" "NM_001270404:c.-51+21828G>C" "FIVE_PRIME_INTRON" "Benign" "rs550375221" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 10 1322 0.0076 0 1006 0 0 694 0 0 1008 0 0 978 0 10 5008 0.00199681
490693 "chr21:35861608:A>G" "KCNE1" "NM_001270404:c.-51+21791T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs565445267" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490694 "chr21:35861669:C>T" "KCNE1" "NM_001270404:c.-51+21730G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs548193263" "This variant is a VUS because it does not have enough information." 0 1322 0 2 1006 0.002 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
490695 "chr21:35861683:C>A" "KCNE1" "NM_001270404:c.-51+21716G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs566502186" "This variant is a VUS because it does not have enough information."
490696 "chr21:35861717:A>G" "KCNE1" "NM_001270404:c.-51+21682T>C" "FIVE_PRIME_INTRON" "Benign" "rs2834497" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 291 1322 0.2201 156 1006 0.1551 115 694 0.1657 299 1008 0.2966 171 978 0.1748 1032 5008 0.20607
490697 "chr21:35861730:A>C" "KCNE1" "NM_001270404:c.-51+21669T>G" "FIVE_PRIME_INTRON" "Benign" "rs565587597" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1 1322 0.0008 0 1006 0 1 694 0.0014 3 1008 0.003 5 978 0.0051 10 5008 0.00199681
490698 "chr21:35861735:C>T" "KCNE1" "NM_001270404:c.-51+21664G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs371656111" "This variant is a VUS because it does not have enough information."
490699 "chr21:35861755:G>C" "KCNE1" "NM_001270404:c.-51+21644C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs536236732" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490700 "chr21:35861792:G>A" "KCNE1" "NM_001270404:c.-51+21607C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs548224181" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
490701 "chr21:35861802:G>A" "KCNE1" "NM_001270404:c.-51+21597C>T" "FIVE_PRIME_INTRON" "Benign" "rs7278198" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 20 1006 0.0199 1 694 0.0014 28 1008 0.0278 47 978 0.0481 96 5008 0.0191693
490702 "chr21:35861823:C>T" "KCNE1" "NM_001270404:c.-51+21576G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs796453513" "This variant is a VUS because it does not have enough information."
490703 "chr21:35861856:C>T" "KCNE1" "NM_001270404:c.-51+21543G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs766727958" "This variant is a VUS because it does not have enough information."
490704 "chr21:35861873:CCCTCAACTT>-" "KCNE1" "NM_001270404:c.-51+21526_-51+21537delAAGTTGAGGG" "FIVE_PRIME_INTRON" "Benign" "rs141390875" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 41 1322 0.031 0 1006 0 0 694 0 0 1008 0 0 978 0 41 5008 0.0081869
490705 "chr21:35861874:C>A" "KCNE1" "NM_001270404:c.-51+21525G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs777112731" "This variant is a VUS because it does not have enough information."
490706 "chr21:35861909:G>T" "KCNE1" "NM_001270404:c.-51+21490C>A" "FIVE_PRIME_INTRON" "Benign" "rs141630857" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 7 1322 0.0053 0 1006 0 0 694 0 0 1008 0 0 978 0 7 5008 0.00139776
490707 "chr21:35861910:G>A" "KCNE1" "NM_001270404:c.-51+21489C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs558342729" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
490708 "chr21:35861955:G>A" "KCNE1" "NM_001270404:c.-51+21444C>T" "FIVE_PRIME_INTRON" "Benign" "rs150525275" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 14 1008 0.0139 39 978 0.0399 53 5008 0.0105831
490709 "chr21:35861974:T>C" "KCNE1" "NM_001270404:c.-51+21425A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs538747870" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490710 "chr21:35861999:A>G" "KCNE1" "NM_001270404:c.-51+21400T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs191347213" "This variant is a VUS because it does not have enough information." 5 1322 0.0038 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 6 5008 0.00119808
490711 "chr21:35862031:T>C" "KCNE1" "NM_001270404:c.-51+21368A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs572388350" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490712 "chr21:35862041:T>C" "KCNE1" "NM_001270404:c.-51+21358A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs759833322" "This variant is a VUS because it does not have enough information."
490713 "chr21:35862087:C>T" "KCNE1" "NM_001270404:c.-51+21312G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs183491236" "This variant is a VUS because it does not have enough information."
490714 "chr21:35862093:G>A" "KCNE1" "NM_001270404:c.-51+21306C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs764876805" "This variant is a VUS because it does not have enough information."
490715 "chr21:35862102:G>A" "KCNE1" "NM_001270404:c.-51+21297C>T" "FIVE_PRIME_INTRON" "Benign" "rs114225208" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 32 1322 0.0242 0 1006 0 0 694 0 0 1008 0 0 978 0 32 5008 0.00638978
490716 "chr21:35862106:C>T" "KCNE1" "NM_001270404:c.-51+21293G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs570789286" "This variant is a VUS because it does not have enough information."
490717 "chr21:35862144:C>T" "KCNE1" "NM_001270404:c.-51+21255G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs554991737" "This variant is a VUS because it does not have enough information." 4 1322 0.003 0 1006 0 0 694 0 0 1008 0 0 978 0 4 5008 0.000798722
490718 "chr21:35862167:C>A" "KCNE1" "NM_001270404:c.-51+21232G>T" "FIVE_PRIME_INTRON" "Benign" "rs140389577" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 8 1322 0.0061 0 1006 0 0 694 0 0 1008 0 0 978 0 8 5008 0.00159744
490719 "chr21:35862212:C>A" "KCNE1" "NM_001270404:c.-51+21187G>T" "FIVE_PRIME_INTRON" "Benign" "rs73365358" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 73 1322 0.0552 0 1006 0 6 694 0.0086 22 1008 0.0218 38 978 0.0389 139 5008 0.0277556
490720 "chr21:35862278:G>A" "KCNE1" "NM_001270404:c.-51+21121C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs565482837" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490721 "chr21:35862280:G>T" "KCNE1" "NM_001270404:c.-51+21119C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs189864460" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
490722 "chr21:35862296:G>C" "KCNE1" "NM_001270404:c.-51+21103C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs192802626" "This variant is a VUS because it does not have enough information." 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042
490723 "chr21:35862299:T>C" "KCNE1" "NM_001270404:c.-51+21100A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs559385559" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490724 "chr21:35862302:G>A" "KCNE1" "NM_001270404:c.-51+21097C>T" "FIVE_PRIME_INTRON" "Benign" "rs117692374" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1 1322 0.0008 9 1006 0.0089 5 694 0.0072 0 1008 0 40 978 0.0409 55 5008 0.0109824
490725 "chr21:35862358:G>A" "KCNE1" "NM_001270404:c.-51+21041C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs796861220" "This variant is a VUS because it does not have enough information."
490726 "chr21:35862404:T>C" "KCNE1" "NM_001270404:c.-51+20995A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs757958783" "This variant is a VUS because it does not have enough information."
490727 "chr21:35862430:T>C" "KCNE1" "NM_001270404:c.-51+20969A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs747956256" "This variant is a VUS because it does not have enough information."
490728 "chr21:35862433:C>A" "KCNE1" "NM_001270404:c.-51+20966G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs377738404" "This variant is a VUS because it does not have enough information."
490729 "chr21:35862435:G>A" "KCNE1" "NM_001270404:c.-51+20964C>T" "FIVE_PRIME_INTRON" "Benign" "rs73365359" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 63 1322 0.0477 0 1006 0 6 694 0.0086 49 1008 0.0486 39 978 0.0399 157 5008 0.0313498
490730 "chr21:35862444:G>A" "KCNE1" "NM_001270404:c.-51+20955C>T" "FIVE_PRIME_INTRON" "Benign" "rs117041259" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 49 1008 0.0486 39 978 0.0399 88 5008 0.0175719
490731 "chr21:35862465:C>T" "KCNE1" "NM_001270404:c.-51+20934G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs184858300" "This variant is a VUS because it does not have enough information." 4 1322 0.003 0 1006 0 0 694 0 0 1008 0 0 978 0 4 5008 0.000798722
490732 "chr21:35862476:G>C" "KCNE1" "NM_001270404:c.-51+20923C>G" "FIVE_PRIME_INTRON" "Benign" "rs79643136" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 63 1322 0.0477 0 1006 0 6 694 0.0086 49 1008 0.0486 39 978 0.0399 157 5008 0.0313498
490733 "chr21:35862481:C>T" "KCNE1" "NM_001270404:c.-51+20918G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs757493167" "This variant is a VUS because it does not have enough information."
490734 "chr21:35862483:C>T" "KCNE1" "NM_001270404:c.-51+20916G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs190087947" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
490735 "chr21:35862484:C>T" "KCNE1" "NM_001270404:c.-51+20915G>A" "FIVE_PRIME_INTRON" "Benign" "rs4817663" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 63 1322 0.0477 2 1006 0.002 40 694 0.0576 102 1008 0.1012 42 978 0.0429 249 5008 0.0497204
490736 "chr21:35862485:A>C" "KCNE1" "NM_001270404:c.-51+20914T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs77638646" "This variant is a VUS because it does not have enough information."
490737 "chr21:35862487:C>G" "KCNE1" "NM_001270404:c.-51+20912G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs745922673" "This variant is a VUS because it does not have enough information."
490738 "chr21:35862492:G>A" "KCNE1" "NM_001270404:c.-51+20907C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs181671826" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490739 "chr21:35862512:T>C" "KCNE1" "NM_001270404:c.-51+20887A>G" "FIVE_PRIME_INTRON" "Benign" "rs4817664" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 63 1322 0.0477 2 1006 0.002 40 694 0.0576 103 1008 0.1022 42 978 0.0429 250 5008 0.0499201
490740 "chr21:35862518:G>T" "KCNE1" "NM_001270404:c.-51+20881C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs538050591" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 1 694 0.0014 0 1008 0 0 978 0 2 5008 0.000399361
490741 "chr21:35862582:G>C" "KCNE1" "NM_001270404:c.-51+20817C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs554958267" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 2 5008 0.000399361
490742 "chr21:35862587:->G" "KCNE1" "NM_001270404:c.-51+20812_-51+20813insC" "FIVE_PRIME_INTRON" "Unknown significance" "rs34717302" "This variant is a VUS because it does not have enough information."
490743 "chr21:35862630:T>C" "KCNE1" "NM_001270404:c.-51+20769A>G" "FIVE_PRIME_INTRON" "Benign" "rs147713424" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 25 1322 0.0189 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 26 5008 0.00519169
490744 "chr21:35862632:G>C" "KCNE1" "NM_001270404:c.-51+20767C>G" "FIVE_PRIME_INTRON" "Benign" "rs4817665" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 2 1006 0.002 34 694 0.049 102 1008 0.1012 42 978 0.0429 180 5008 0.0359425
490745 "chr21:35862635:A>G" "KCNE1" "NM_001270404:c.-51+20764T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs559286261" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490746 "chr21:35862639:T>C" "KCNE1" "NM_001270404:c.-51+20760A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs757320203" "This variant is a VUS because it does not have enough information."
490747 "chr21:35862642:T>C" "KCNE1" "NM_001270404:c.-51+20757A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs577549193" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490748 "chr21:35862646:G>A" "KCNE1" "NM_001270404:c.-51+20753C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs541593215" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490749 "chr21:35862654:T>C" "KCNE1" "NM_001270404:c.-51+20745A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs556133499" "This variant is a VUS because it does not have enough information."
490750 "chr21:35862671:G>C" "KCNE1" "NM_001270404:c.-51+20728C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs781003051" "This variant is a VUS because it does not have enough information."
490751 "chr21:35862683:A>G" "KCNE1" "NM_001270404:c.-51+20716T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs574378501" "This variant is a VUS because it does not have enough information." 0 1322 0 2 1006 0.002 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
490752 "chr21:35862695:G>A" "KCNE1" "NM_001270404:c.-51+20704C>T" "FIVE_PRIME_INTRON" "Benign" "rs117902201" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 2 1322 0.0015 34 1006 0.0338 18 694 0.0259 1 1008 0.001 4 978 0.0041 59 5008 0.0117812
490753 "chr21:35862727:T>C" "KCNE1" "NM_001270404:c.-51+20672A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs541517759" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490754 "chr21:35862751:A>G" "KCNE1" "NM_001270404:c.-51+20648T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs371388494" "This variant is a VUS because it does not have enough information."
490755 "chr21:35862767:C>T" "KCNE1" "NM_001270404:c.-51+20632G>A" "FIVE_PRIME_INTRON" "Benign" "rs562945588" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 14 1322 0.0106 0 1006 0 0 694 0 0 1008 0 0 978 0 14 5008 0.00279553
490756 "chr21:35862768:G>A" "KCNE1" "NM_001270404:c.-51+20631C>T" "FIVE_PRIME_INTRON" "Benign" "rs112358482" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 36 1322 0.0272 0 1006 0 4 694 0.0058 0 1008 0 0 978 0 40 5008 0.00798722
490757 "chr21:35862820:T>C" "KCNE1" "NM_001270404:c.-51+20579A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs779151429" "This variant is a VUS because it does not have enough information."
490758 "chr21:35862821:G>T" "KCNE1" "NM_001270404:c.-51+20578C>A" "FIVE_PRIME_INTRON" "Benign" "rs116087349" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 42 1322 0.0318 0 1006 0 0 694 0 0 1008 0 0 978 0 42 5008 0.00838658
490759 "chr21:35862834:T>C" "KCNE1" "NM_001270404:c.-51+20565A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs772111418" "This variant is a VUS because it does not have enough information."
490760 "chr21:35862950:C>A" "KCNE1" "NM_001270404:c.-51+20449G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs570396095" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490761 "chr21:35862970:A>G" "KCNE1" "NM_001270404:c.-51+20429T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs559532052" "This variant is a VUS because it does not have enough information."
490762 "chr21:35862988:->T" "KCNE1" "NM_001270404:c.-51+20411_-51+20412insA" "FIVE_PRIME_INTRON" "Benign" "rs151247020" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 34 1322 0.0257 45 1006 0.0447 39 694 0.0562 91 1008 0.0903 91 978 0.093 300 5008 0.0599042
490763 "chr21:35863020:T>C" "KCNE1" "NM_001270404:c.-51+20379A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs773350352" "This variant is a VUS because it does not have enough information."
490764 "chr21:35863138:C>T" "KCNE1" "NM_001270404:c.-51+20261G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs528297780" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
490765 "chr21:35863139:G>A" "KCNE1" "NM_001270404:c.-51+20260C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs747503979" "This variant is a VUS because it does not have enough information."
490766 "chr21:35863146:C>T" "KCNE1" "NM_001270404:c.-51+20253G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs771413221" "This variant is a VUS because it does not have enough information."
490767 "chr21:35863147:G>A" "KCNE1" "NM_001270404:c.-51+20252C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs777009369" "This variant is a VUS because it does not have enough information."
490768 "chr21:35863158:C>T" "KCNE1" "NM_001270404:c.-51+20241G>A" "FIVE_PRIME_INTRON" "Benign" "rs11911439" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 63 1322 0.0477 2 1006 0.002 39 694 0.0562 102 1008 0.1012 42 978 0.0429 248 5008 0.0495208
490769 "chr21:35863158:CT>TG" "KCNE1" "Unknown significance" "rs35599881" "This variant is a VUS because it does not have enough information."
490770 "chr21:35863159:T>G" "KCNE1" "NM_001270404:c.-51+20240A>C" "FIVE_PRIME_INTRON" "Benign" "rs11911624" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 63 1322 0.0477 2 1006 0.002 39 694 0.0562 102 1008 0.1012 42 978 0.0429 248 5008 0.0495208
490771 "chr21:35863160:C>T" "KCNE1" "NM_001270404:c.-51+20239G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs184965415" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490772 "chr21:35863163:G>A" "KCNE1" "NM_001270404:c.-51+20236C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs189299798" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490773 "chr21:35863184:G>A" "KCNE1" "NM_001270404:c.-51+20215C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs540333362" "This variant is a VUS because it does not have enough information."
490774 "chr21:35863205:G>A" "KCNE1" "NM_001270404:c.-51+20194C>T" "FIVE_PRIME_INTRON" "Benign" "rs180886660" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 36 1322 0.0272 0 1006 0 4 694 0.0058 0 1008 0 0 978 0 40 5008 0.00798722
490775 "chr21:35863216:C>T" "KCNE1" "NM_001270404:c.-51+20183G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs759895859" "This variant is a VUS because it does not have enough information."
490776 "chr21:35863217:G>A" "KCNE1" "NM_001270404:c.-51+20182C>T" "FIVE_PRIME_INTRON" "Benign" "rs11911511" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 63 1322 0.0477 2 1006 0.002 40 694 0.0576 102 1008 0.1012 42 978 0.0429 249 5008 0.0497204
490777 "chr21:35863217:G>C" "KCNE1" "NM_001270404:c.-51+20182C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs11911511" "This variant is a VUS because it does not have enough information."
490778 "chr21:35863244:->C" "KCNE1" "NM_001270404:c.-51+20155_-51+20156insG" "FIVE_PRIME_INTRON" "Unknown significance" "rs370457677" "This variant is a VUS because it does not have enough information."
490779 "chr21:35863247:C>T" "KCNE1" "NM_001270404:c.-51+20152G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs144894150" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490780 "chr21:35863254:G>A" "KCNE1" "NM_001270404:c.-51+20145C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs577635980" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 2 978 0.002 2 5008 0.000399361
490781 "chr21:35863259:->ACACACAC" "KCNE1" "NM_001270404:c.-51+20140_-51+20141insGTGTGTGT" "FIVE_PRIME_INTRON" "Unknown significance" "rs530973774" "This variant is a VUS because it does not have enough information."
490782 "chr21:35863260:->C" "KCNE1" "NM_001270404:c.-51+20139_-51+20140insG" "FIVE_PRIME_INTRON" "Benign" "rs34623244" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 25 1322 0.0189 1 1006 0.001 1 694 0.0014 0 1008 0 0 978 0 27 5008 0.00539137
490783 "chr21:35863260:->CACACAC" "KCNE1" "NM_001270404:c.-51+20139_-51+20140insGTGTGTG" "FIVE_PRIME_INTRON" "Benign" "rs34623244" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 30 1322 0.0227 2 1006 0.002 34 694 0.049 94 1008 0.0933 28 978 0.0286 188 5008 0.0375399
490784 "chr21:35863260:A>C" "KCNE1" "NM_001270404:c.-51+20139T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs185492210" "This variant is a VUS because it does not have enough information."
490785 "chr21:35863261:->ACAC" "KCNE1" "NM_001270404:c.-51+20138_-51+20139insGTGT" "FIVE_PRIME_INTRON" "Benign" "rs34082954" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 61 1322 0.0461 54 1006 0.0537 21 694 0.0303 50 1008 0.0496 58 978 0.0593 244 5008 0.048722
490786 "chr21:35863261:->ACACAC" "KCNE1" "NM_001270404:c.-51+20138_-51+20139insGTGTGT" "FIVE_PRIME_INTRON" "Unknown significance" "rs34082954" "This variant is a VUS because it does not have enough information." 6 1322 0.0045 0 1006 0 0 694 0 0 1008 0 0 978 0 6 5008 0.00119808
490787 "chr21:35863261:->C" "KCNE1" "NM_001270404:c.-51+20138_-51+20139insG" "FIVE_PRIME_INTRON" "Benign" "rs34082954" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 55 1322 0.0416 3 1006 0.003 35 694 0.0504 94 1008 0.0933 28 978 0.0286 215 5008 0.0429313
490788 "chr21:35863261:AC>-" "KCNE1" "NM_001270404:c.-51+20138_-51+20141delGT" "FIVE_PRIME_INTRON" "Unknown significance" "rs372494381" "This variant is a VUS because it does not have enough information."
490789 "chr21:35863262:C>A" "KCNE1" "NM_001270404:c.-51+20137G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs534975609" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490790 "chr21:35863324:C>T" "KCNE1" "NM_001270404:c.-51+20075G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs762758225" "This variant is a VUS because it does not have enough information."
490791 "chr21:35863331:G>A" "KCNE1" "NM_001270404:c.-51+20068C>T" "FIVE_PRIME_INTRON" "Benign" "rs11088286" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 108 1322 0.0817 242 1006 0.2406 258 694 0.3718 604 1008 0.5992 177 978 0.181 1389 5008 0.277356
490792 "chr21:35863346:C>G" "KCNE1" "NM_001270404:c.-51+20053G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs56280814" "This variant is a VUS because it does not have enough information."
490793 "chr21:35863350:T>C" "KCNE1" "NM_001270404:c.-51+20049A>G" "FIVE_PRIME_INTRON" "Benign" "rs574886148" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 7 1006 0.007 0 694 0 0 1008 0 0 978 0 7 5008 0.00139776
490794 "chr21:35863362:G>C" "KCNE1" "NM_001270404:c.-51+20037C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs541953595" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 3 694 0.0043 0 1008 0 0 978 0 3 5008 0.000599042
490795 "chr21:35863390:C>T" "KCNE1" "NM_001270404:c.-51+20009G>A" "FIVE_PRIME_INTRON" "Benign" "rs6517236" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 373 1322 0.2821 244 1006 0.2425 307 694 0.4424 706 1008 0.7004 219 978 0.2239 1849 5008 0.369209
490796 "chr21:35863417:A>G" "KCNE1" "NM_001270404:c.-51+19982T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs574927852" "This variant is a VUS because it does not have enough information." 6 1322 0.0045 0 1006 0 0 694 0 0 1008 0 0 978 0 6 5008 0.00119808
490797 "chr21:35863423:C>T" "KCNE1" "NM_001270404:c.-51+19976G>A" "FIVE_PRIME_INTRON" "Benign" "rs62211548" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 67 1322 0.0507 193 1006 0.1918 78 694 0.1124 2 1008 0.002 194 978 0.1984 534 5008 0.106629
490798 "chr21:35863424:G>A" "KCNE1" "NM_001270404:c.-51+19975C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs528983659" "This variant is a VUS because it does not have enough information."
490799 "chr21:35863437:AAAAAAAAAA>-" "KCNE1" "NM_001270404:c.-51+19962_-51+19973delTTTTTTTTTT" "FIVE_PRIME_INTRON" "Benign" "rs202000532" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 789 1322 0.5968 630 1006 0.6262 516 694 0.7435 966 1008 0.9583 670 978 0.6851 3571 5008 0.713059
490800 "chr21:35863437:AAA>-" "KCNE1" "NM_001270404:c.-51+19962_-51+19966delTTT" "FIVE_PRIME_INTRON" "Unknown significance" "rs56087176" "This variant is a VUS because it does not have enough information."
490801 "chr21:35863437:AAAA>-" "KCNE1" "NM_001270404:c.-51+19962_-51+19967delTTTT" "FIVE_PRIME_INTRON" "Unknown significance" "rs750044971" "This variant is a VUS because it does not have enough information."
490802 "chr21:35863437:AAAAAAAAAAA>-" "KCNE1" "NM_001270404:c.-51+19962_-51+19974delTTTTTTTTTTT" "FIVE_PRIME_INTRON" "Unknown significance" "rs773914568" "This variant is a VUS because it does not have enough information."
490803 "chr21:35863437:AAAAAAAAAAAAAAA>-" "KCNE1" "NM_001270404:c.-51+19962_-51+19978delTTTTTTTTTTTTTTT" "FIVE_PRIME_INTRON" "Unknown significance" "rs112693369" "This variant is a VUS because it does not have enough information."
490804 "chr21:35863443:A>T" "KCNE1" "NM_001270404:c.-51+19956T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs78395767" "This variant is a VUS because it does not have enough information."
490805 "chr21:35863462:A>G" "KCNE1" "NM_001270404:c.-51+19937T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs79326465" "This variant is a VUS because it does not have enough information."
490806 "chr21:35863486:G>A" "KCNE1" "NM_001270404:c.-51+19913C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs143662494" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490807 "chr21:35863493:T>C" "KCNE1" "NM_001270404:c.-51+19906A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs528402429" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490808 "chr21:35863517:G>A" "KCNE1" "NM_001270404:c.-51+19882C>T" "FIVE_PRIME_INTRON" "Benign" "rs16991741" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 57 1322 0.0431 0 1006 0 3 694 0.0043 0 1008 0 2 978 0.002 62 5008 0.0123802
490809 "chr21:35863523:C>T" "KCNE1" "NM_001270404:c.-51+19876G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs561964687" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490810 "chr21:35863529:G>T" "KCNE1" "NM_001270404:c.-51+19870C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs151047443" "This variant is a VUS because it does not have enough information." 6 1322 0.0045 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 8 5008 0.00159744
490811 "chr21:35863555:G>A" "KCNE1" "NM_001270404:c.-51+19844C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs141296413" "This variant is a VUS because it does not have enough information." 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403
490812 "chr21:35863569:T>C" "KCNE1" "NM_001270404:c.-51+19830A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs530396019" "This variant is a VUS because it does not have enough information."
490813 "chr21:35863582:A>G" "KCNE1" "NM_001270404:c.-51+19817T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs372820668" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490814 "chr21:35863603:G>C" "KCNE1" "NM_001270404:c.-51+19796C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs537511862" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490815 "chr21:35863633:G>A" "KCNE1" "NM_001270404:c.-51+19766C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs552617245" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490816 "chr21:35863650:T>C" "KCNE1" "NM_001270404:c.-51+19749A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs372872660" "This variant is a VUS because it does not have enough information."
490817 "chr21:35863668:G>A" "KCNE1" "NM_001270404:c.-51+19731C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs190990843" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
490818 "chr21:35863689:G>-" "KCNE1" "NM_001270404:c.-51+19710delC" "FIVE_PRIME_INTRON" "Unknown significance" "rs542683026" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 3 1008 0.003 0 978 0 3 5008 0.000599042
490819 "chr21:35863716:G>T" "KCNE1" "NM_001270404:c.-51+19683C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs369546235" "This variant is a VUS because it does not have enough information."
490820 "chr21:35863736:->T" "KCNE1" "NM_001270404:c.-51+19663_-51+19664insA" "FIVE_PRIME_INTRON" "Benign" "rs112270967" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 228 1322 0.1725 104 1006 0.1034 81 694 0.1167 98 1008 0.0972 148 978 0.1513 659 5008 0.131589
490821 "chr21:35863736:->TT" "KCNE1" "NM_001270404:c.-51+19663_-51+19664insAA" "FIVE_PRIME_INTRON" "Unknown significance" "rs112270967" "This variant is a VUS because it does not have enough information."
490822 "chr21:35863760:T>A" "KCNE1" "NM_001270404:c.-51+19639A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs566442363" "This variant is a VUS because it does not have enough information."
490823 "chr21:35863823:C>T" "KCNE1" "NM_001270404:c.-51+19576G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs372195486" "This variant is a VUS because it does not have enough information."
490824 "chr21:35863837:T>C" "KCNE1" "NM_001270404:c.-51+19562A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs535333115" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490825 "chr21:35863889:G>A" "KCNE1" "NM_001270404:c.-51+19510C>T" "FIVE_PRIME_INTRON" "Benign" "rs145070098" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 84 1322 0.0635 0 1006 0 5 694 0.0072 0 1008 0 0 978 0 89 5008 0.0177716
490826 "chr21:35863925:G>A" "KCNE1" "NM_001270404:c.-51+19474C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs750353679" "This variant is a VUS because it does not have enough information."
490827 "chr21:35863954:T>C" "KCNE1" "NM_001270404:c.-51+19445A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs575019168" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490828 "chr21:35863964:G>C" "KCNE1" "NM_001270404:c.-51+19435C>G" "FIVE_PRIME_INTRON" "Benign" "rs138658340" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 5 1008 0.005 0 978 0 5 5008 0.000998403
490829 "chr21:35863973:G>T" "KCNE1" "NM_001270404:c.-51+19426C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs556667885" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490830 "chr21:35863986:G>C" "KCNE1" "NM_001270404:c.-51+19413C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs181414559" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490831 "chr21:35863992:T>C" "KCNE1" "NM_001270404:c.-51+19407A>G" "FIVE_PRIME_INTRON" "Benign" "rs58894573" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 65 1322 0.0492 2 1006 0.002 40 694 0.0576 102 1008 0.1012 42 978 0.0429 251 5008 0.0501198
490832 "chr21:35864021:G>A" "KCNE1" "NM_001270404:c.-51+19378C>T" "FIVE_PRIME_INTRON" "Benign" "rs8130942" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 64 1322 0.0484 2 1006 0.002 40 694 0.0576 102 1008 0.1012 42 978 0.0429 250 5008 0.0499201
490833 "chr21:35864039:G>T" "KCNE1" "NM_001270404:c.-51+19360C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs112523172" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490834 "chr21:35864079:G>A" "KCNE1" "NM_001270404:c.-51+19320C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs527292311" "This variant is a VUS because it does not have enough information."
490835 "chr21:35864089:C>T" "KCNE1" "NM_001270404:c.-51+19310G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs549034870" "This variant is a VUS because it does not have enough information."
490836 "chr21:35864145:C>T" "KCNE1" "NM_001270404:c.-51+19254G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs540561144" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361
490837 "chr21:35864150:T>A" "KCNE1" "NM_001270404:c.-51+19249A>T" "FIVE_PRIME_INTRON" "Benign" "rs55847142" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 57 1322 0.0431 0 1006 0 4 694 0.0058 0 1008 0 0 978 0 61 5008 0.0121805
490838 "chr21:35864155:G>T" "KCNE1" "NM_001270404:c.-51+19244C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs758679292" "This variant is a VUS because it does not have enough information."
490839 "chr21:35864167:A>T" "KCNE1" "NM_001270404:c.-51+19232T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs562302829" "This variant is a VUS because it does not have enough information."
490840 "chr21:35864188:C>T" "KCNE1" "NM_001270404:c.-51+19211G>A" "FIVE_PRIME_INTRON" "Benign" "rs141769282" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 32 1322 0.0242 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 33 5008 0.00658946
490841 "chr21:35864206:G>A" "KCNE1" "NM_001270404:c.-51+19193C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs777985820" "This variant is a VUS because it does not have enough information."
490842 "chr21:35864211:G>T" "KCNE1" "NM_001270404:c.-51+19188C>A" "FIVE_PRIME_INTRON" "Benign" "rs79357675" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 2 1006 0.002 34 694 0.049 102 1008 0.1012 42 978 0.0429 180 5008 0.0359425
490843 "chr21:35864274:A>G" "KCNE1" "NM_001270404:c.-51+19125T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs747025386" "This variant is a VUS because it does not have enough information."
490844 "chr21:35864280:T>C" "KCNE1" "NM_001270404:c.-51+19119A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs562636447" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490845 "chr21:35864295:A>T" "KCNE1" "NM_001270404:c.-51+19104T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs531034057" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 4 978 0.0041 4 5008 0.000798722
490846 "chr21:35864331:T>C" "KCNE1" "NM_001270404:c.-51+19068A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs552660220" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490847 "chr21:35864359:T>G" "KCNE1" "NM_001270404:c.-51+19040A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs186425692" "This variant is a VUS because it does not have enough information." 0 1322 0 2 1006 0.002 1 694 0.0014 0 1008 0 0 978 0 3 5008 0.000599042
490848 "chr21:35864364:C>T" "KCNE1" "NM_001270404:c.-51+19035G>A" "FIVE_PRIME_INTRON" "Benign" "rs138092722" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 7 1008 0.0069 0 978 0 7 5008 0.00139776
490849 "chr21:35864391:G>A" "KCNE1" "NM_001270404:c.-51+19008C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs191679718" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490850 "chr21:35864404:->A" "KCNE1" "NM_001270404:c.-51+18995_-51+18996insT" "FIVE_PRIME_INTRON" "Unknown significance" "rs34885611" "This variant is a VUS because it does not have enough information."
490851 "chr21:35864414:A>G" "KCNE1" "NM_001270404:c.-51+18985T>C" "FIVE_PRIME_INTRON" "Benign" "rs77694973" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 11 1322 0.0083 0 1006 0 0 694 0 0 1008 0 0 978 0 11 5008 0.00219649
490852 "chr21:35864453:G>A" "KCNE1" "NM_001270404:c.-51+18946C>T" "FIVE_PRIME_INTRON" "Benign" "rs59274419" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 24 1322 0.0182 0 1006 0 0 694 0 5 1008 0.005 1 978 0.001 30 5008 0.00599042
490853 "chr21:35864456:T>C" "KCNE1" "NM_001270404:c.-51+18943A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs557148583" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490854 "chr21:35864457:C>T" "KCNE1" "NM_001270404:c.-51+18942G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs182768388" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490855 "chr21:35864470:C>G" "KCNE1" "NM_001270404:c.-51+18929G>C" "FIVE_PRIME_INTRON" "Benign" "rs11909094" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 64 1322 0.0484 2 1006 0.002 40 694 0.0576 102 1008 0.1012 42 978 0.0429 250 5008 0.0499201
490856 "chr21:35864470:C>T" "KCNE1" "NM_001270404:c.-51+18929G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs11909094" "This variant is a VUS because it does not have enough information."
490857 "chr21:35864501:C>A" "KCNE1" "NM_001270404:c.-51+18898G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs770189025" "This variant is a VUS because it does not have enough information."
490858 "chr21:35864574:T>C" "KCNE1" "NM_001270404:c.-51+18825A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs765150436" "This variant is a VUS because it does not have enough information."
490859 "chr21:35864580:T>A" "KCNE1" "NM_001270404:c.-51+18819A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs557420953" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490860 "chr21:35864597:T>C" "KCNE1" "NM_001270404:c.-51+18802A>G" "FIVE_PRIME_INTRON" "Benign" "rs75308381" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 2 1006 0.002 34 694 0.049 102 1008 0.1012 42 978 0.0429 180 5008 0.0359425
490861 "chr21:35864604:T>C" "KCNE1" "NM_001270404:c.-51+18795A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs539823915" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490862 "chr21:35864628:C>A" "KCNE1" "NM_001270404:c.-51+18771G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs763422074" "This variant is a VUS because it does not have enough information."
490863 "chr21:35864646:G>A" "KCNE1" "NM_001270404:c.-51+18753C>T" "FIVE_PRIME_INTRON" "Benign" "rs11909829" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 64 1322 0.0484 2 1006 0.002 40 694 0.0576 102 1008 0.1012 42 978 0.0429 250 5008 0.0499201
490864 "chr21:35864699:->TTT" "KCNE1" "NM_001270404:c.-51+18700_-51+18701insAAA" "FIVE_PRIME_INTRON" "Benign" "rs564346128" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 2 1006 0.002 33 694 0.0476 100 1008 0.0992 42 978 0.0429 177 5008 0.0353435
490865 "chr21:35864699:->T" "KCNE1" "NM_001270404:c.-51+18700_-51+18701insA" "FIVE_PRIME_INTRON" "Unknown significance" "rs564346128" "This variant is a VUS because it does not have enough information."
490866 "chr21:35864775:T>C" "KCNE1" "NM_001270404:c.-51+18624A>G" "FIVE_PRIME_INTRON" "Benign" "rs11910011" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 64 1322 0.0484 2 1006 0.002 40 694 0.0576 102 1008 0.1012 42 978 0.0429 250 5008 0.0499201
490867 "chr21:35864794:C>T" "KCNE1" "NM_001270404:c.-51+18605G>A" "FIVE_PRIME_INTRON" "Benign" "rs11909817" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 64 1322 0.0484 3 1006 0.003 40 694 0.0576 102 1008 0.1012 42 978 0.0429 251 5008 0.0501198
490868 "chr21:35864795:G>A" "KCNE1" "NM_001270404:c.-51+18604C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs562673180" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490869 "chr21:35864825:T>C" "KCNE1" "NM_001270404:c.-51+18574A>G" "FIVE_PRIME_INTRON" "Benign" "rs12626780" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 35 1322 0.0265 244 1006 0.2425 255 694 0.3674 602 1008 0.5972 177 978 0.181 1313 5008 0.262181
490870 "chr21:35864829:T>A" "KCNE1" "NM_001270404:c.-51+18570A>T" "FIVE_PRIME_INTRON" "Benign" "rs58146066" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 29 1322 0.0219 0 1006 0 0 694 0 0 1008 0 0 978 0 29 5008 0.00579073
490871 "chr21:35864850:C>T" "KCNE1" "NM_001270404:c.-51+18549G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs537587116" "This variant is a VUS because it does not have enough information."
490872 "chr21:35864858:C>G" "KCNE1" "NM_001270404:c.-51+18541G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs564411071" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490873 "chr21:35864895:C>T" "KCNE1" "NM_001270404:c.-51+18504G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs528516614" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 2 5008 0.000399361
490874 "chr21:35864921:T>G" "KCNE1" "NM_001270404:c.-51+18478A>C" "FIVE_PRIME_INTRON" "Benign" "rs11910067" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 64 1322 0.0484 2 1006 0.002 40 694 0.0576 102 1008 0.1012 42 978 0.0429 250 5008 0.0499201
490875 "chr21:35864930:G>A" "KCNE1" "NM_001270404:c.-51+18469C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs568408419" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490876 "chr21:35864955:T>C" "KCNE1" "NM_001270404:c.-51+18444A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs143869753" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490877 "chr21:35865000:G>A" "KCNE1" "NM_001270404:c.-51+18399C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs549930306" "This variant is a VUS because it does not have enough information."
490878 "chr21:35865023:A>G" "KCNE1" "NM_001270404:c.-51+18376T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs766185484" "This variant is a VUS because it does not have enough information."
490879 "chr21:35865094:C>G" "KCNE1" "NM_001270404:c.-51+18305G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs140324225" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490880 "chr21:35865107:->T" "KCNE1" "NM_001270404:c.-51+18292_-51+18293insA" "FIVE_PRIME_INTRON" "Benign" "rs61664165" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 233 1322 0.1762 194 1006 0.1928 82 694 0.1182 3 1008 0.003 197 978 0.2014 709 5008 0.141573
490881 "chr21:35865116:A>T" "KCNE1" "NM_001270404:c.-51+18283T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs377048077" "This variant is a VUS because it does not have enough information."
490882 "chr21:35865155:T>A" "KCNE1" "NM_001270404:c.-51+18244A>T" "FIVE_PRIME_INTRON" "Benign" "rs78377484" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 64 1322 0.0484 2 1006 0.002 40 694 0.0576 102 1008 0.1012 42 978 0.0429 250 5008 0.0499201
490883 "chr21:35865214:G>A" "KCNE1" "NM_001270404:c.-51+18185C>T" "FIVE_PRIME_INTRON" "Benign" "rs73365367" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 64 1322 0.0484 2 1006 0.002 40 694 0.0576 102 1008 0.1012 42 978 0.0429 250 5008 0.0499201
490884 "chr21:35865236:C>T" "KCNE1" "NM_001270404:c.-51+18163G>A" "FIVE_PRIME_INTRON" "Benign" "rs73365368" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 64 1322 0.0484 2 1006 0.002 40 694 0.0576 102 1008 0.1012 42 978 0.0429 250 5008 0.0499201
490885 "chr21:35865236:C>G" "KCNE1" "NM_001270404:c.-51+18163G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs73365368" "This variant is a VUS because it does not have enough information."
490886 "chr21:35865254:C>T" "KCNE1" "NM_001270404:c.-51+18145G>A" "FIVE_PRIME_INTRON" "Benign" "rs566464449" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 0 1008 0 10 978 0.0102 10 5008 0.00199681
490887 "chr21:35865306:C>A" "KCNE1" "NM_001270404:c.-51+18093G>T" "FIVE_PRIME_INTRON" "Benign" "rs7276099" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 64 1322 0.0484 2 1006 0.002 40 694 0.0576 102 1008 0.1012 42 978 0.0429 250 5008 0.0499201
490888 "chr21:35865309:T>C" "KCNE1" "NM_001270404:c.-51+18090A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs555076024" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490889 "chr21:35865311:C>T" "KCNE1" "NM_001270404:c.-51+18088G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs187800844" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490890 "chr21:35865349:T>C" "KCNE1" "NM_001270404:c.-51+18050A>G" "FIVE_PRIME_INTRON" "Benign" "rs147383236" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 20 1322 0.0151 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 21 5008 0.00419329
490891 "chr21:35865360:G>A" "KCNE1" "NM_001270404:c.-51+18039C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs111938038" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490892 "chr21:35865395:G>T" "KCNE1" "NM_001270404:c.-51+18004C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs770761752" "This variant is a VUS because it does not have enough information."
490893 "chr21:35865438:A>G" "KCNE1" "NM_001270404:c.-51+17961T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs577948971" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490894 "chr21:35865453:A>-" "KCNE1" "NM_001270404:c.-51+17946delT" "FIVE_PRIME_INTRON" "Unknown significance" "rs529300661" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 2 1008 0.002 0 978 0 3 5008 0.000599042
490895 "chr21:35865476:G>A" "KCNE1" "NM_001270404:c.-51+17923C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs374514477" "This variant is a VUS because it does not have enough information."
490896 "chr21:35865480:A>C" "KCNE1" "NM_001270404:c.-51+17919T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs781193968" "This variant is a VUS because it does not have enough information."
490897 "chr21:35865564:A>G" "KCNE1" "NM_001270404:c.-51+17835T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs746371398" "This variant is a VUS because it does not have enough information."
490898 "chr21:35865570:A>T" "KCNE1" "NM_001270404:c.-51+17829T>A" "FIVE_PRIME_INTRON" "Benign" "rs140893446" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 7 1322 0.0053 0 1006 0 0 694 0 0 1008 0 0 978 0 7 5008 0.00139776
490899 "chr21:35865575:T>A" "KCNE1" "NM_001270404:c.-51+17824A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs770139314" "This variant is a VUS because it does not have enough information."
490900 "chr21:35865586:C>T" "KCNE1" "NM_001270404:c.-51+17813G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs560267564" "This variant is a VUS because it does not have enough information." 4 1322 0.003 0 1006 0 0 694 0 0 1008 0 0 978 0 4 5008 0.000798722
490901 "chr21:35865605:C>G" "KCNE1" "NM_001270404:c.-51+17794G>C" "FIVE_PRIME_INTRON" "Benign" "rs183234809" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 1 1006 0.001 0 694 0 5 1008 0.005 0 978 0 6 5008 0.00119808
490902 "chr21:35865616:A>G" "KCNE1" "NM_001270404:c.-51+17783T>C" "FIVE_PRIME_INTRON" "Benign" "rs7280045" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 67 1322 0.0507 2 1006 0.002 41 694 0.0591 102 1008 0.1012 42 978 0.0429 254 5008 0.0507188
490903 "chr21:35865664:T>C" "KCNE1" "NM_001270404:c.-51+17735A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs749626671" "This variant is a VUS because it does not have enough information."
490904 "chr21:35865665:T>C" "KCNE1" "NM_001270404:c.-51+17734A>G" "FIVE_PRIME_INTRON" "Benign" "rs561939729" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 0 1008 0 6 978 0.0061 6 5008 0.00119808
490905 "chr21:35865684:C>T" "KCNE1" "NM_001270404:c.-51+17715G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs187757691" "This variant is a VUS because it does not have enough information."
490906 "chr21:35865685:G>A" "KCNE1" "NM_001270404:c.-51+17714C>T" "FIVE_PRIME_INTRON" "Benign" "rs142407485" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 7 1008 0.0069 0 978 0 7 5008 0.00139776
490907 "chr21:35865752:A>T" "KCNE1" "NM_001270404:c.-51+17647T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs774129166" "This variant is a VUS because it does not have enough information."
490908 "chr21:35865771:T>C" "KCNE1" "NM_001270404:c.-51+17628A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs528756281" "This variant is a VUS because it does not have enough information."
490909 "chr21:35865788:A>G" "KCNE1" "NM_001270404:c.-51+17611T>C" "FIVE_PRIME_INTRON" "Benign" "rs372035363" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 9 1008 0.0089 0 978 0 9 5008 0.00179712
490910 "chr21:35865808:G>T" "KCNE1" "NM_001270404:c.-51+17591C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs569185301" "This variant is a VUS because it does not have enough information." 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403
490911 "chr21:35865815:G>A" "KCNE1" "NM_001270404:c.-51+17584C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs761417043" "This variant is a VUS because it does not have enough information."
490912 "chr21:35865834:C>T" "KCNE1" "NM_001270404:c.-51+17565G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs151316256" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361
490913 "chr21:35865855:T>C" "KCNE1" "NM_001270404:c.-51+17544A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs771609600" "This variant is a VUS because it does not have enough information."
490914 "chr21:35865859:C>T" "KCNE1" "NM_001270404:c.-51+17540G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs551696983" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 1 978 0.001 2 5008 0.000399361
490915 "chr21:35865860:G>A" "KCNE1" "NM_001270404:c.-51+17539C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs567011343" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 1 1008 0.001 0 978 0 2 5008 0.000399361
490916 "chr21:35865863:G>A" "KCNE1" "NM_001270404:c.-51+17536C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs139406018" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 3 694 0.0043 0 1008 0 0 978 0 3 5008 0.000599042
490917 "chr21:35865870:->T" "KCNE1" "NM_001270404:c.-51+17529_-51+17530insA" "FIVE_PRIME_INTRON" "Unknown significance" "rs572859300" "This variant is a VUS because it does not have enough information."
490918 "chr21:35865924:C>A" "KCNE1" "NM_001270404:c.-51+17475G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs549057496" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490919 "chr21:35865958:TTTTG>-" "KCNE1" "NM_001270404:c.-51+17441_-51+17447delCAAAA" "FIVE_PRIME_INTRON" "Benign" "rs144075852" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 111 1322 0.084 0 1006 0 4 694 0.0058 0 1008 0 0 978 0 115 5008 0.0229633
490920 "chr21:35865980:G>A" "KCNE1" "NM_001270404:c.-51+17419C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs567314568" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490921 "chr21:35866017:C>A" "KCNE1" "NM_001270404:c.-51+17382G>T" "FIVE_PRIME_INTRON" "Benign" "rs150073917" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 2 1006 0.002 34 694 0.049 102 1008 0.1012 42 978 0.0429 180 5008 0.0359425
490922 "chr21:35866061:G>T" "KCNE1" "NM_001270404:c.-51+17338C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs556528363" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490923 "chr21:35866065:G>T" "KCNE1" "NM_001270404:c.-51+17334C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs760247458" "This variant is a VUS because it does not have enough information."
490924 "chr21:35866067:C>G" "KCNE1" "NM_001270404:c.-51+17332G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs578016677" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490925 "chr21:35866137:T>C" "KCNE1" "NM_001270404:c.-51+17262A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs146540865" "This variant is a VUS because it does not have enough information." 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403
490926 "chr21:35866141:T>C" "KCNE1" "NM_001270404:c.-51+17258A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs766239177" "This variant is a VUS because it does not have enough information."
490927 "chr21:35866145:T>C" "KCNE1" "NM_001270404:c.-51+17254A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs776581224" "This variant is a VUS because it does not have enough information."
490928 "chr21:35866213:G>T" "KCNE1" "NM_001270404:c.-51+17186C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs553695485" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 3 1008 0.003 0 978 0 3 5008 0.000599042
490929 "chr21:35866235:G>A" "KCNE1" "NM_001270404:c.-51+17164C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs572159918" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490930 "chr21:35866248:G>C" "KCNE1" "NM_001270404:c.-51+17151C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs369200613" "This variant is a VUS because it does not have enough information."
490931 "chr21:35866270:C>G" "KCNE1" "NM_001270404:c.-51+17129G>C" "FIVE_PRIME_INTRON" "Benign" "rs531105521" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 0 1008 0 23 978 0.0235 23 5008 0.00459265
490932 "chr21:35866287:T>C" "KCNE1" "NM_001270404:c.-51+17112A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs562196429" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490933 "chr21:35866289:G>T" "KCNE1" "NM_001270404:c.-51+17110C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs573724769" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490934 "chr21:35866297:A>G" "KCNE1" "NM_001270404:c.-51+17102T>C" "FIVE_PRIME_INTRON" "Benign" "rs141253862" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 5 1008 0.005 0 978 0 5 5008 0.000998403
490935 "chr21:35866298:G>A" "KCNE1" "NM_001270404:c.-51+17101C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs751371126" "This variant is a VUS because it does not have enough information."
490936 "chr21:35866354:C>-" "KCNE1" "NM_001270404:c.-51+17045delG" "FIVE_PRIME_INTRON" "Benign" "rs551560824" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 10 1322 0.0076 0 1006 0 0 694 0 0 1008 0 0 978 0 10 5008 0.00199681
490937 "chr21:35866364:A>C" "KCNE1" "NM_001270404:c.-51+17035T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs765056017" "This variant is a VUS because it does not have enough information."
490938 "chr21:35866365:A>G" "KCNE1" "NM_001270404:c.-51+17034T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs372052567" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490939 "chr21:35866373:T>C" "KCNE1" "NM_001270404:c.-51+17026A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs533453181" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490940 "chr21:35866382:C>T" "KCNE1" "NM_001270404:c.-51+17017G>A" "FIVE_PRIME_INTRON" "Benign" "rs145039285" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 6 1322 0.0045 0 1006 0 0 694 0 0 1008 0 5 978 0.0051 11 5008 0.00219649
490941 "chr21:35866386:T>C" "KCNE1" "NM_001270404:c.-51+17013A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs192632335" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490942 "chr21:35866463:T>C" "KCNE1" "NM_001270404:c.-51+16936A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs527879469" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490943 "chr21:35866472:A>T" "KCNE1" "NM_001270404:c.-51+16927T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs558727604" "This variant is a VUS because it does not have enough information."
490944 "chr21:35866488:A>G" "KCNE1" "NM_001270404:c.-51+16911T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs376690105" "This variant is a VUS because it does not have enough information."
490945 "chr21:35866502:G>C" "KCNE1" "NM_001270404:c.-51+16897C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs368958713" "This variant is a VUS because it does not have enough information."
490946 "chr21:35866518:C>G" "KCNE1" "NM_001270404:c.-51+16881G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs184854734" "This variant is a VUS because it does not have enough information."
490947 "chr21:35866523:T>C" "KCNE1" "NM_001270404:c.-51+16876A>G" "FIVE_PRIME_INTRON" "Benign" "rs188117658" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 8 1322 0.0061 0 1006 0 3 694 0.0043 0 1008 0 0 978 0 11 5008 0.00219649
490948 "chr21:35866588:A>G" "KCNE1" "NM_001270404:c.-51+16811T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs567349139" "This variant is a VUS because it does not have enough information." 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042
490949 "chr21:35866597:G>A" "KCNE1" "NM_001270404:c.-51+16802C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs751801642" "This variant is a VUS because it does not have enough information."
490950 "chr21:35866618:G>A" "KCNE1" "NM_001270404:c.-51+16781C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs757476400" "This variant is a VUS because it does not have enough information."
490951 "chr21:35866629:T>C" "KCNE1" "NM_001270404:c.-51+16770A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs767791955" "This variant is a VUS because it does not have enough information."
490952 "chr21:35866643:T>G" "KCNE1" "NM_001270404:c.-51+16756A>C" "FIVE_PRIME_INTRON" "Benign" "rs146816440" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 2 1006 0.002 34 694 0.049 102 1008 0.1012 42 978 0.0429 180 5008 0.0359425
490953 "chr21:35866646:G>C" "KCNE1" "NM_001270404:c.-51+16753C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs549818786" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490954 "chr21:35866666:T>C" "KCNE1" "NM_001270404:c.-51+16733A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs571223324" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490955 "chr21:35866679:G>A" "KCNE1" "NM_001270404:c.-51+16720C>T" "FIVE_PRIME_INTRON" "Benign" "rs140319734" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 20 1006 0.0199 1 694 0.0014 0 1008 0 7 978 0.0072 28 5008 0.00559105
490956 "chr21:35866682:->T" "KCNE1" "NM_001270404:c.-51+16717_-51+16718insA" "FIVE_PRIME_INTRON" "Unknown significance" "rs758761305" "This variant is a VUS because it does not have enough information."
490957 "chr21:35866682:T>C" "KCNE1" "NM_001270404:c.-51+16717A>G" "FIVE_PRIME_INTRON" "Benign" "rs7277315" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 71 1322 0.0537 0 1006 0 3 694 0.0043 0 1008 0 0 978 0 74 5008 0.0147764
490958 "chr21:35866724:A>C" "KCNE1" "NM_001270404:c.-51+16675T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs749856227" "This variant is a VUS because it does not have enough information."
490959 "chr21:35866764:A>G" "KCNE1" "NM_001270404:c.-51+16635T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs551083299" "This variant is a VUS because it does not have enough information."
490960 "chr21:35866772:G>C" "KCNE1" "NM_001270404:c.-51+16627C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs572181063" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361
490961 "chr21:35866822:A>C" "KCNE1" "NM_001270404:c.-51+16577T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs536425160" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490962 "chr21:35866825:T>C" "KCNE1" "NM_001270404:c.-51+16574A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs554314618" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
490963 "chr21:35866827:T>C" "KCNE1" "NM_001270404:c.-51+16572A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs573811891" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
490964 "chr21:35866846:T>C" "KCNE1" "NM_001270404:c.-51+16553A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs569238971" "This variant is a VUS because it does not have enough information."
490965 "chr21:35866852:T>A" "KCNE1" "NM_001270404:c.-51+16547A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs544256521" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
490966 "chr21:35866957:G>C" "KCNE1" "NM_001270404:c.-51+16442C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs375921099" "This variant is a VUS because it does not have enough information."
490967 "chr21:35866973:T>C" "KCNE1" "NM_001270404:c.-51+16426A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs544408015" "This variant is a VUS because it does not have enough information."
490968 "chr21:35866978:C>T" "KCNE1" "NM_001270404:c.-51+16421G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs755366122" "This variant is a VUS because it does not have enough information."
490969 "chr21:35866979:G>A" "KCNE1" "NM_001270404:c.-51+16420C>T" "FIVE_PRIME_INTRON" "Benign" "rs117056616" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 2 1006 0.002 34 694 0.049 102 1008 0.1012 42 978 0.0429 180 5008 0.0359425
490970 "chr21:35867000:A>G" "KCNE1" "NM_001270404:c.-51+16399T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs577609592" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
490971 "chr21:35867065:G>A" "KCNE1" "NM_001270404:c.-51+16334C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs558783452" "This variant is a VUS because it does not have enough information."
490972 "chr21:35867098:G>T" "KCNE1" "NM_001270404:c.-51+16301C>A" "FIVE_PRIME_INTRON" "Benign" "rs73365369" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 17 1322 0.0129 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 19 5008 0.00379393
490973 "chr21:35867133:T>C" "KCNE1" "NM_001270404:c.-51+16266A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs747826028" "This variant is a VUS because it does not have enough information."
490974 "chr21:35867158:G>C" "KCNE1" "NM_001270404:c.-51+16241C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs771570058" "This variant is a VUS because it does not have enough information."
490975 "chr21:35867198:A>G" "KCNE1" "NM_001270404:c.-51+16201T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs779079050" "This variant is a VUS because it does not have enough information."
490976 "chr21:35867205:G>A" "KCNE1" "NM_001270404:c.-51+16194C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs570765331" "This variant is a VUS because it does not have enough information."
490977 "chr21:35867245:G>A" "KCNE1" "NM_001270404:c.-51+16154C>T" "FIVE_PRIME_INTRON" "Benign" "rs148045702" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 11 1322 0.0083 0 1006 0 0 694 0 0 1008 0 0 978 0 11 5008 0.00219649
490978 "chr21:35867260:A>G" "KCNE1" "NM_001270404:c.-51+16139T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs527911299" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490979 "chr21:35867265:C>T" "KCNE1" "NM_001270404:c.-51+16134G>A" "FIVE_PRIME_INTRON" "Benign" "rs7277153" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 583 1322 0.441 492 1006 0.4891 406 694 0.585 757 1008 0.751 472 978 0.4826 2710 5008 0.541134
490980 "chr21:35867352:C>T" "KCNE1" "NM_001270404:c.-51+16047G>A" "FIVE_PRIME_INTRON" "Benign" "rs561435080" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 0 1008 0 17 978 0.0174 17 5008 0.00339457
490981 "chr21:35867366:A>C" "KCNE1" "NM_001270404:c.-51+16033T>G" "FIVE_PRIME_INTRON" "Benign" "rs111463248" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 37 1322 0.028 0 1006 0 4 694 0.0058 0 1008 0 0 978 0 41 5008 0.0081869
490982 "chr21:35867401:G>C" "KCNE1" "NM_001270404:c.-51+15998C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs772643442" "This variant is a VUS because it does not have enough information."
490983 "chr21:35867411:T>C" "KCNE1" "NM_001270404:c.-51+15988A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs770449803" "This variant is a VUS because it does not have enough information."
490984 "chr21:35867436:T>C" "KCNE1" "NM_001270404:c.-51+15963A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs376115741" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
490985 "chr21:35867480:T>C" "KCNE1" "NM_001270404:c.-51+15919A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs571311517" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361
490986 "chr21:35867491:T>G" "KCNE1" "NM_001270404:c.-51+15908A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs776528087" "This variant is a VUS because it does not have enough information."
490987 "chr21:35867507:T>C" "KCNE1" "NM_001270404:c.-51+15892A>G" "FIVE_PRIME_INTRON" "Benign" "rs138616492" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 7 1322 0.0053 0 1006 0 0 694 0 0 1008 0 0 978 0 7 5008 0.00139776
490988 "chr21:35867528:T>C" "KCNE1" "NM_001270404:c.-51+15871A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs759535659" "This variant is a VUS because it does not have enough information."
490989 "chr21:35867542:G>T" "KCNE1" "NM_001270404:c.-51+15857C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs765001017" "This variant is a VUS because it does not have enough information."
490990 "chr21:35867572:C>T" "KCNE1" "NM_001270404:c.-51+15827G>A" "FIVE_PRIME_INTRON" "Benign" "rs547402946" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 0 1008 0 7 978 0.0072 7 5008 0.00139776
490991 "chr21:35867573:G>A" "KCNE1" "NM_001270404:c.-51+15826C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs775088031" "This variant is a VUS because it does not have enough information."
490992 "chr21:35867589:G>T" "KCNE1" "NM_001270404:c.-51+15810C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs565986668" "This variant is a VUS because it does not have enough information." 5 1322 0.0038 0 1006 0 0 694 0 1 1008 0.001 0 978 0 6 5008 0.00119808
490993 "chr21:35867605:C>T" "KCNE1" "NM_001270404:c.-51+15794G>A" "FIVE_PRIME_INTRON" "Benign" "rs12626448" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 356 1322 0.2693 298 1006 0.2962 325 694 0.4683 756 1008 0.75 278 978 0.2843 2013 5008 0.401957
490994 "chr21:35867625:T>C" "KCNE1" "NM_001270404:c.-51+15774A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs767592144" "This variant is a VUS because it does not have enough information."
490995 "chr21:35867648:T>C" "KCNE1" "NM_001270404:c.-51+15751A>G" "FIVE_PRIME_INTRON" "Benign" "rs117308548" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 2 1006 0.002 34 694 0.049 102 1008 0.1012 42 978 0.0429 180 5008 0.0359425
490996 "chr21:35867691:C>T" "KCNE1" "NM_001270404:c.-51+15708G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs569463007" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 1 1008 0.001 0 978 0 2 5008 0.000399361
490997 "chr21:35867699:T>C" "KCNE1" "NM_001270404:c.-51+15700A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs557051213" "This variant is a VUS because it does not have enough information."
490998 "chr21:35867766:A>G" "KCNE1" "NM_001270404:c.-51+15633T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs368557450" "This variant is a VUS because it does not have enough information."
490999 "chr21:35867784:G>T" "KCNE1" "NM_001270404:c.-51+15615C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs370850658" "This variant is a VUS because it does not have enough information."
491000 "chr21:35867795:A>C" "KCNE1" "NM_001270404:c.-51+15604T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs537994344" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491001 "chr21:35867808:C>G" "KCNE1" "NM_001270404:c.-51+15591G>C" "FIVE_PRIME_INTRON" "Benign" "rs146456953" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 170 1322 0.1286 54 1006 0.0537 25 694 0.036 50 1008 0.0496 58 978 0.0593 357 5008 0.0712859
491002 "chr21:35867809:T>-" "KCNE1" "NM_001270404:c.-51+15590delA" "FIVE_PRIME_INTRON" "Benign" "rs200276112" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 10 1322 0.0076 8 1006 0.008 37 694 0.0533 105 1008 0.1042 51 978 0.0521 211 5008 0.0421326
491003 "chr21:35867861:A>G" "KCNE1" "NM_001270404:c.-51+15538T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs577988233" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491004 "chr21:35867942:C>G" "KCNE1" "NM_001270404:c.-51+15457G>C" "FIVE_PRIME_INTRON" "Benign" "rs2211699" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 356 1322 0.2693 298 1006 0.2962 325 694 0.4683 754 1008 0.748 278 978 0.2843 2011 5008 0.401558
491005 "chr21:35868033:G>C" "KCNE1" "NM_001270404:c.-51+15366C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs553854872" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491006 "chr21:35868062:C>T" "KCNE1" "NM_001270404:c.-51+15337G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs192184124" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
491007 "chr21:35868084:C>T" "KCNE1" "NM_001270404:c.-51+15315G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs528025402" "This variant is a VUS because it does not have enough information."
491008 "chr21:35868085:G>A" "KCNE1" "NM_001270404:c.-51+15314C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs564293020" "This variant is a VUS because it does not have enough information."
491009 "chr21:35868123:T>C" "KCNE1" "NM_001270404:c.-51+15276A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs543304251" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 2 5008 0.000399361
491010 "chr21:35868128:->T" "KCNE1" "NM_001270404:c.-51+15271_-51+15272insA" "FIVE_PRIME_INTRON" "Benign" "rs201563552" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 37 1322 0.028 0 1006 0 4 694 0.0058 0 1008 0 0 978 0 41 5008 0.0081869
491011 "chr21:35868144:T>C" "KCNE1" "NM_001270404:c.-51+15255A>G" "FIVE_PRIME_INTRON" "Benign" "rs11701049" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 67 1322 0.0507 194 1006 0.1928 78 694 0.1124 2 1008 0.002 195 978 0.1994 536 5008 0.107029
491012 "chr21:35868146:T>-" "KCNE1" "NM_001270404:c.-51+15253delA" "FIVE_PRIME_INTRON" "Benign" "rs563958323" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 11 1006 0.0109 3 694 0.0043 0 1008 0 4 978 0.0041 18 5008 0.00359425
491013 "chr21:35868162:T>C" "KCNE1" "NM_001270404:c.-51+15237A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs755602682" "This variant is a VUS because it does not have enough information."
491014 "chr21:35868189:G>T" "KCNE1" "NM_001270404:c.-51+15210C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs113436632" "This variant is a VUS because it does not have enough information."
491015 "chr21:35868200:T>C" "KCNE1" "NM_001270404:c.-51+15199A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs531939991" "This variant is a VUS because it does not have enough information." 3 1322 0.0023 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 4 5008 0.000798722
491016 "chr21:35868335:G>A" "KCNE1" "NM_001270404:c.-51+15064C>T" "FIVE_PRIME_INTRON" "Benign" "rs117113608" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 2 1006 0.002 34 694 0.049 102 1008 0.1012 42 978 0.0429 180 5008 0.0359425
491017 "chr21:35868366:C>T" "KCNE1" "NM_001270404:c.-51+15033G>A" "FIVE_PRIME_INTRON" "Benign" "rs11700954" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 357 1322 0.27 298 1006 0.2962 325 694 0.4683 756 1008 0.75 278 978 0.2843 2014 5008 0.402157
491018 "chr21:35868372:T>G" "KCNE1" "NM_001270404:c.-51+15027A>C" "FIVE_PRIME_INTRON" "Benign" "rs111638856" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 17 1322 0.0129 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 19 5008 0.00379393
491019 "chr21:35868375:->T" "KCNE1" "NM_001270404:c.-51+15024_-51+15025insA" "FIVE_PRIME_INTRON" "Benign" "rs549485389" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 185 1322 0.1399 58 1006 0.0577 26 694 0.0375 53 1008 0.0526 61 978 0.0624 383 5008 0.0764776
491020 "chr21:35868465:A>G" "KCNE1" "NM_001270404:c.-51+14934T>C" "FIVE_PRIME_INTRON" "Benign" "rs111494344" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 64 1322 0.0484 2 1006 0.002 40 694 0.0576 102 1008 0.1012 42 978 0.0429 250 5008 0.0499201
491021 "chr21:35868467:G>A" "KCNE1" "NM_001270404:c.-51+14932C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs565498963" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 3 1008 0.003 0 978 0 3 5008 0.000599042
491022 "chr21:35868517:G>A" "KCNE1" "NM_001270404:c.-51+14882C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs530002997" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
491023 "chr21:35868572:C>T" "KCNE1" "NM_001270404:c.-51+14827G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs548074888" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491024 "chr21:35868573:G>A" "KCNE1" "NM_001270404:c.-51+14826C>T" "FIVE_PRIME_INTRON" "Benign" "rs55700417" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 57 1322 0.0431 0 1006 0 4 694 0.0058 0 1008 0 0 978 0 61 5008 0.0121805
491025 "chr21:35868592:T>C" "KCNE1" "NM_001270404:c.-51+14807A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs200074472" "This variant is a VUS because it does not have enough information."
491026 "chr21:35868606:C>T" "KCNE1" "NM_001270404:c.-51+14793G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs761645100" "This variant is a VUS because it does not have enough information."
491027 "chr21:35868607:G>A" "KCNE1" "NM_001270404:c.-51+14792C>T" "FIVE_PRIME_INTRON" "Benign" "rs567878217" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 10 1006 0.0099 0 694 0 1 1008 0.001 1 978 0.001 12 5008 0.00239617
491028 "chr21:35868618:G>T" "KCNE1" "NM_001270404:c.-51+14781C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs551341030" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491029 "chr21:35868618:G>A" "KCNE1" "NM_001270404:c.-51+14781C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs551341030" "This variant is a VUS because it does not have enough information."
491030 "chr21:35868622:T>C" "KCNE1" "NM_001270404:c.-51+14777A>G" "FIVE_PRIME_INTRON" "Benign" "rs4817668" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 890 1322 0.6732 539 1006 0.5358 457 694 0.6585 889 1008 0.8819 624 978 0.638 3399 5008 0.678714
491031 "chr21:35868627:T>A" "KCNE1" "NM_001270404:c.-51+14772A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs538726119" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
491032 "chr21:35868637:C>T" "KCNE1" "NM_001270404:c.-51+14762G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs78692280" "This variant is a VUS because it does not have enough information."
491033 "chr21:35868640:G>C" "KCNE1" "NM_001270404:c.-51+14759C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs547241082" "This variant is a VUS because it does not have enough information."
491034 "chr21:35868715:C>T" "KCNE1" "NM_001270404:c.-51+14684G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs746724867" "This variant is a VUS because it does not have enough information."
491035 "chr21:35868721:G>A" "KCNE1" "NM_001270404:c.-51+14678C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs554147916" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
491036 "chr21:35868730:G>A" "KCNE1" "NM_001270404:c.-51+14669C>T" "FIVE_PRIME_INTRON" "Benign" "rs115951137" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 7 1322 0.0053 0 1006 0 0 694 0 0 1008 0 0 978 0 7 5008 0.00139776
491037 "chr21:35868733:G>A" "KCNE1" "NM_001270404:c.-51+14666C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs565961499" "This variant is a VUS because it does not have enough information."
491038 "chr21:35868752:T>A" "KCNE1" "NM_001270404:c.-51+14647A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs776176646" "This variant is a VUS because it does not have enough information."
491039 "chr21:35868773:G>T" "KCNE1" "NM_001270404:c.-51+14626C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs543391497" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
491040 "chr21:35868810:G>A" "KCNE1" "NM_001270404:c.-51+14589C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs189055541" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491041 "chr21:35868811:G>T" "KCNE1" "NM_001270404:c.-51+14588C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs745393858" "This variant is a VUS because it does not have enough information."
491042 "chr21:35868836:T>G" "KCNE1" "NM_001270404:c.-51+14563A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs576745555" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
491043 "chr21:35868837:C>T" "KCNE1" "NM_001270404:c.-51+14562G>A" "FIVE_PRIME_INTRON" "Benign" "rs8128964" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 2 1006 0.002 34 694 0.049 103 1008 0.1022 42 978 0.0429 181 5008 0.0361422
491044 "chr21:35868857:A>G" "KCNE1" "NM_001270404:c.-51+14542T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs565302319" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361
491045 "chr21:35868861:G>-" "KCNE1" "NM_001270404:c.-51+14538delC" "FIVE_PRIME_INTRON" "Benign" "rs199877352" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 101 1322 0.0764 2 1006 0.002 5 694 0.0072 39 1008 0.0387 59 978 0.0603 206 5008 0.0411342
491046 "chr21:35868862:->T" "KCNE1" "NM_001270404:c.-51+14537_-51+14538insA" "FIVE_PRIME_INTRON" "Benign" "rs148735567" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 2 1006 0.002 34 694 0.049 100 1008 0.0992 41 978 0.0419 177 5008 0.0353435
491047 "chr21:35868877:C>A" "KCNE1" "NM_001270404:c.-51+14522G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs182050603" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
491048 "chr21:35868913:C>T" "KCNE1" "NM_001270404:c.-51+14486G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs571150073" "This variant is a VUS because it does not have enough information."
491049 "chr21:35868914:G>A" "KCNE1" "NM_001270404:c.-51+14485C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs540721285" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
491050 "chr21:35868926:T>C" "KCNE1" "NM_001270404:c.-51+14473A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs539390793" "This variant is a VUS because it does not have enough information."
491051 "chr21:35868928:T>C" "KCNE1" "NM_001270404:c.-51+14471A>G" "FIVE_PRIME_INTRON" "Benign" "rs112431854" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 37 1322 0.028 0 1006 0 4 694 0.0058 0 1008 0 0 978 0 41 5008 0.0081869
491052 "chr21:35868950:G>C" "KCNE1" "NM_001270404:c.-51+14449C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs558890274" "This variant is a VUS because it does not have enough information."
491053 "chr21:35868973:C>T" "KCNE1" "NM_001270404:c.-51+14426G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs529630935" "This variant is a VUS because it does not have enough information." 4 1322 0.003 0 1006 0 0 694 0 0 1008 0 0 978 0 4 5008 0.000798722
491054 "chr21:35868992:T>C" "KCNE1" "NM_001270404:c.-51+14407A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs548110021" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
491055 "chr21:35869016:A>C" "KCNE1" "NM_001270404:c.-51+14383T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs563223072" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
491056 "chr21:35869024:T>G" "KCNE1" "NM_001270404:c.-51+14375A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs773271860" "This variant is a VUS because it does not have enough information."
491057 "chr21:35869033:T>C" "KCNE1" "NM_001270404:c.-51+14366A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs761049534" "This variant is a VUS because it does not have enough information."
491058 "chr21:35869058:T>C" "KCNE1" "NM_001270404:c.-51+14341A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs376602884" "This variant is a VUS because it does not have enough information."
491059 "chr21:35869092:T>A" "KCNE1" "NM_001270404:c.-51+14307A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs530690464" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491060 "chr21:35869110:G>A" "KCNE1" "NM_001270404:c.-51+14289C>T" "FIVE_PRIME_INTRON" "Benign" "rs11088287" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 111 1322 0.084 242 1006 0.2406 260 694 0.3746 604 1008 0.5992 178 978 0.182 1395 5008 0.278554
491061 "chr21:35869119:G>T" "KCNE1" "NM_001270404:c.-51+14280C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs753914487" "This variant is a VUS because it does not have enough information."
491062 "chr21:35869230:AA>-" "KCNE1" "NM_001270404:c.-51+14169_-51+14172delTT" "FIVE_PRIME_INTRON" "Unknown significance" "rs760589938" "This variant is a VUS because it does not have enough information."
491063 "chr21:35869235:G>A" "KCNE1" "NM_001270404:c.-51+14164C>T" "FIVE_PRIME_INTRON" "Benign" "rs116556323" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 52 1322 0.0393 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 54 5008 0.0107827
491064 "chr21:35869274:G>A" "KCNE1" "NM_001270404:c.-51+14125C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs375828051" "This variant is a VUS because it does not have enough information."
491065 "chr21:35869278:C>T" "KCNE1" "NM_001270404:c.-51+14121G>A" "FIVE_PRIME_INTRON" "Benign" "rs142967779" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 8 1006 0.008 4 694 0.0058 0 1008 0 0 978 0 12 5008 0.00239617
491066 "chr21:35869283:G>T" "KCNE1" "NM_001270404:c.-51+14116C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs184851195" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
491067 "chr21:35869350:C>A" "KCNE1" "NM_001270404:c.-51+14049G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs189284346" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 3 694 0.0043 0 1008 0 0 978 0 3 5008 0.000599042
491068 "chr21:35869381:G>A" "KCNE1" "NM_001270404:c.-51+14018C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs536633121" "This variant is a VUS because it does not have enough information." 3 1322 0.0023 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 4 5008 0.000798722
491069 "chr21:35869388:C>A" "KCNE1" "NM_001270404:c.-51+14011G>T" "FIVE_PRIME_INTRON" "Benign" "rs180772329" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 11 1322 0.0083 0 1006 0 0 694 0 0 1008 0 0 978 0 11 5008 0.00219649
491070 "chr21:35869388:C>T" "KCNE1" "NM_001270404:c.-51+14011G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs180772329" "This variant is a VUS because it does not have enough information."
491071 "chr21:35869418:A>T" "KCNE1" "NM_001270404:c.-51+13981T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs576824283" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
491072 "chr21:35869434:G>A" "KCNE1" "NM_001270404:c.-51+13965C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs537697390" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
491073 "chr21:35869487:G>A" "KCNE1" "NM_001270404:c.-51+13912C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs186407061" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361
491074 "chr21:35869497:T>C" "KCNE1" "NM_001270404:c.-51+13902A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs758668457" "This variant is a VUS because it does not have enough information."
491075 "chr21:35869499:G>C" "KCNE1" "NM_001270404:c.-51+13900C>G" "FIVE_PRIME_INTRON" "Benign" "rs191267447" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 7 1322 0.0053 0 1006 0 0 694 0 0 1008 0 0 978 0 7 5008 0.00139776
491076 "chr21:35869506:T>C" "KCNE1" "NM_001270404:c.-51+13893A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs778240933" "This variant is a VUS because it does not have enough information."
491077 "chr21:35869527:->TGT" "KCNE1" "NM_001270404:c.-51+13872_-51+13873insACA" "FIVE_PRIME_INTRON" "Unknown significance" "rs754552515" "This variant is a VUS because it does not have enough information."
491078 "chr21:35869527:TGT>-" "KCNE1" "NM_001270404:c.-51+13872_-51+13876delACA" "FIVE_PRIME_INTRON" "Unknown significance" "rs778054422" "This variant is a VUS because it does not have enough information."
491079 "chr21:35869548:T>G" "KCNE1" "NM_001270404:c.-51+13851A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs540082581" "This variant is a VUS because it does not have enough information."
491080 "chr21:35869604:T>A" "KCNE1" "NM_001270404:c.-51+13795A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs541160006" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
491081 "chr21:35869625:C>T" "KCNE1" "NM_001270404:c.-51+13774G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs559165715" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 1 1006 0.001 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
491082 "chr21:35869650:A>C" "KCNE1" "NM_001270404:c.-51+13749T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs574120717" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 2 5008 0.000399361
491083 "chr21:35869679:G>A" "KCNE1" "NM_001270404:c.-51+13720C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs146158034" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
491084 "chr21:35869688:T>C" "KCNE1" "NM_001270404:c.-51+13711A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs546679442" "This variant is a VUS because it does not have enough information."
491085 "chr21:35869720:T>A" "KCNE1" "NM_001270404:c.-51+13679A>T" "FIVE_PRIME_INTRON" "Benign" "rs12151998" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 71 1322 0.0537 54 1006 0.0537 21 694 0.0303 50 1008 0.0496 58 978 0.0593 254 5008 0.0507188
491086 "chr21:35869725:C>T" "KCNE1" "NM_001270404:c.-51+13674G>A" "FIVE_PRIME_INTRON" "Benign" "rs12151987" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 181 1322 0.1369 54 1006 0.0537 25 694 0.036 50 1008 0.0496 58 978 0.0593 368 5008 0.0734824
491087 "chr21:35869764:C>A" "KCNE1" "NM_001270404:c.-51+13635G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs745338680" "This variant is a VUS because it does not have enough information."
491088 "chr21:35869797:A>C" "KCNE1" "NM_001270404:c.-51+13602T>G" "FIVE_PRIME_INTRON" "Benign" "rs73365375" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 64 1322 0.0484 0 1006 0 6 694 0.0086 0 1008 0 0 978 0 70 5008 0.0139776
491089 "chr21:35869820:T>G" "KCNE1" "NM_001270404:c.-51+13579A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs542440346" "This variant is a VUS because it does not have enough information."
491090 "chr21:35869839:G>A" "KCNE1" "NM_001270404:c.-51+13560C>T" "FIVE_PRIME_INTRON" "Benign" "rs139999738" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 2 1006 0.002 34 694 0.049 102 1008 0.1012 42 978 0.0429 180 5008 0.0359425
491091 "chr21:35869841:G>T" "KCNE1" "NM_001270404:c.-51+13558C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs528266461" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491092 "chr21:35869851:G>T" "KCNE1" "NM_001270404:c.-51+13548C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs547904852" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491093 "chr21:35869854:A>C" "KCNE1" "NM_001270404:c.-51+13545T>G" "FIVE_PRIME_INTRON" "Benign" "rs566020247" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 5 1008 0.005 0 978 0 5 5008 0.000998403
491094 "chr21:35869895:C>A" "KCNE1" "NM_001270404:c.-51+13504G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs536710168" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491095 "chr21:35869900:C>T" "KCNE1" "NM_001270404:c.-51+13499G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs548611697" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
491096 "chr21:35869917:TCCTTC>-" "KCNE1" "NM_001270404:c.-51+13482_-51+13489delGAAGGA" "FIVE_PRIME_INTRON" "Unknown significance" "rs757650156" "This variant is a VUS because it does not have enough information."
491097 "chr21:35869938:A>G" "KCNE1" "NM_001270404:c.-51+13461T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs371587238" "This variant is a VUS because it does not have enough information."
491098 "chr21:35870019:T>C" "KCNE1" "NM_001270404:c.-51+13380A>G" "FIVE_PRIME_INTRON" "Benign" "rs73365377" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 27 1322 0.0204 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 29 5008 0.00579073
491099 "chr21:35870102:C>T" "KCNE1" "NM_001270404:c.-51+13297G>A" "FIVE_PRIME_INTRON" "Benign" "rs7283178" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 80 1322 0.0605 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 81 5008 0.0161741
491100 "chr21:35870176:T>-" "KCNE1" "NM_001270404:c.-51+13223delA" "FIVE_PRIME_INTRON" "Benign" "rs111292384" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 40 1322 0.0303 0 1006 0 4 694 0.0058 2 1008 0.002 0 978 0 46 5008 0.0091853
491101 "chr21:35870196:T>-" "KCNE1" "NM_001270404:c.-51+13203delA" "FIVE_PRIME_INTRON" "Unknown significance" "rs781716158" "This variant is a VUS because it does not have enough information."
491102 "chr21:35870208:T>G" "KCNE1" "NM_001270404:c.-51+13191A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs779829875" "This variant is a VUS because it does not have enough information."
491103 "chr21:35870215:A>G" "KCNE1" "NM_001270404:c.-51+13184T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs143598877" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491104 "chr21:35870233:C>T" "KCNE1" "NM_001270404:c.-51+13166G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs577399834" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491105 "chr21:35870236:G>A" "KCNE1" "NM_001270404:c.-51+13163C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs749284385" "This variant is a VUS because it does not have enough information."
491106 "chr21:35870250:T>G" "KCNE1" "NM_001270404:c.-51+13149A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs371451733" "This variant is a VUS because it does not have enough information."
491107 "chr21:35870251:C>T" "KCNE1" "NM_001270404:c.-51+13148G>A" "FIVE_PRIME_INTRON" "Benign" "rs117595792" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 12 1008 0.0119 0 978 0 12 5008 0.00239617
491108 "chr21:35870252:G>A" "KCNE1" "NM_001270404:c.-51+13147C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs181566252" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 2 5008 0.000399361
491109 "chr21:35870274:T>C" "KCNE1" "NM_001270404:c.-51+13125A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs574212006" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491110 "chr21:35870280:C>T" "KCNE1" "NM_001270404:c.-51+13119G>A" "FIVE_PRIME_INTRON" "Benign" "rs146799180" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 44 1322 0.0333 0 1006 0 0 694 0 0 1008 0 0 978 0 44 5008 0.00878594
491111 "chr21:35870293:T>C" "KCNE1" "NM_001270404:c.-51+13106A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs572686256" "This variant is a VUS because it does not have enough information."
491112 "chr21:35870315:T>C" "KCNE1" "NM_001270404:c.-51+13084A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs769501341" "This variant is a VUS because it does not have enough information."
491113 "chr21:35870356:C>T" "KCNE1" "NM_001270404:c.-51+13043G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs774850760" "This variant is a VUS because it does not have enough information."
491114 "chr21:35870369:G>T" "KCNE1" "NM_001270404:c.-51+13030C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs761716150" "This variant is a VUS because it does not have enough information."
491115 "chr21:35870415:C>T" "KCNE1" "NM_001270404:c.-51+12984G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs771213729" "This variant is a VUS because it does not have enough information."
491116 "chr21:35870423:C>T" "KCNE1" "NM_001270404:c.-51+12976G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs556544356" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 2 978 0.002 2 5008 0.000399361
491117 "chr21:35870472:C>T" "KCNE1" "NM_001270404:c.-51+12927G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs574891009" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491118 "chr21:35870497:C>T" "KCNE1" "NM_001270404:c.-51+12902G>A" "FIVE_PRIME_INTRON" "Benign" "rs140496192" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 6 1008 0.006 0 978 0 6 5008 0.00119808
491119 "chr21:35870512:T>C" "KCNE1" "NM_001270404:c.-51+12887A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs186058662" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491120 "chr21:35870562:G>A" "KCNE1" "NM_001270404:c.-51+12837C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs539120559" "This variant is a VUS because it does not have enough information."
491121 "chr21:35870597:C>T" "KCNE1" "NM_001270404:c.-51+12802G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs190473029" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
491122 "chr21:35870599:T>C" "KCNE1" "NM_001270404:c.-51+12800A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs777026158" "This variant is a VUS because it does not have enough information."
491123 "chr21:35870636:A>G" "KCNE1" "NM_001270404:c.-51+12763T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs540069255" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
491124 "chr21:35870657:G>A" "KCNE1" "NM_001270404:c.-51+12742C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs561823137" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
491125 "chr21:35870681:C>T" "KCNE1" "NM_001270404:c.-51+12718G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs546205698" "This variant is a VUS because it does not have enough information." 0 1322 0 3 1006 0.003 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042
491126 "chr21:35870682:C>T" "KCNE1" "NM_001270404:c.-51+12717G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs774223856" "This variant is a VUS because it does not have enough information."
491127 "chr21:35870705:G>C" "KCNE1" "NM_001270404:c.-51+12694C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs765408367" "This variant is a VUS because it does not have enough information."
491128 "chr21:35870725:G>A" "KCNE1" "NM_001270404:c.-51+12674C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs761769698" "This variant is a VUS because it does not have enough information."
491129 "chr21:35870745:A>C" "KCNE1" "NM_001270404:c.-51+12654T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs548697584" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
491130 "chr21:35870753:G>A" "KCNE1" "NM_001270404:c.-51+12646C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs183416338" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361
491131 "chr21:35870818:C>T" "KCNE1" "NM_001270404:c.-51+12581G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs375288312" "This variant is a VUS because it does not have enough information."
491132 "chr21:35870819:G>A" "KCNE1" "NM_001270404:c.-51+12580C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs753114779" "This variant is a VUS because it does not have enough information."
491133 "chr21:35870845:G>A" "KCNE1" "NM_001270404:c.-51+12554C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs530794334" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 1 1006 0.001 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
491134 "chr21:35870875:C>G" "KCNE1" "NM_001270404:c.-51+12524G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs552861354" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491135 "chr21:35870878:C>T" "KCNE1" "NM_001270404:c.-51+12521G>A" "FIVE_PRIME_INTRON" "Benign" "rs73365378" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 64 1322 0.0484 0 1006 0 6 694 0.0086 0 1008 0 0 978 0 70 5008 0.0139776
491136 "chr21:35870885:C>G" "KCNE1" "NM_001270404:c.-51+12514G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs764521199" "This variant is a VUS because it does not have enough information."
491137 "chr21:35870892:C>T" "KCNE1" "NM_001270404:c.-51+12507G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs535293663" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 4 1008 0.004 0 978 0 4 5008 0.000798722
491138 "chr21:35870896:G>A" "KCNE1" "NM_001270404:c.-51+12503C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs188933005" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491139 "chr21:35870907:G>A" "KCNE1" "NM_001270404:c.-51+12492C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs564079621" "This variant is a VUS because it does not have enough information."
491140 "chr21:35870922:C>G" "KCNE1" "NM_001270404:c.-51+12477G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs190832840" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
491141 "chr21:35870959:C>T" "KCNE1" "NM_001270404:c.-51+12440G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs757649285" "This variant is a VUS because it does not have enough information."
491142 "chr21:35870960:G>A" "KCNE1" "NM_001270404:c.-51+12439C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs780771263" "This variant is a VUS because it does not have enough information."
491143 "chr21:35870981:T>C" "KCNE1" "NM_001270404:c.-51+12418A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs535222008" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
491144 "chr21:35870983:T>C" "KCNE1" "NM_001270404:c.-51+12416A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs750122914" "This variant is a VUS because it does not have enough information."
491145 "chr21:35871010:A>G" "KCNE1" "NM_001270404:c.-51+12389T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs556629205" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
491146 "chr21:35871050:A>C" "KCNE1" "NM_001270404:c.-51+12349T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs182637988" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361
491147 "chr21:35871082:G>A" "KCNE1" "NM_001270404:c.-51+12317C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs755543784" "This variant is a VUS because it does not have enough information."
491148 "chr21:35871091:C>T" "KCNE1" "NM_001270404:c.-51+12308G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs779678233" "This variant is a VUS because it does not have enough information."
491149 "chr21:35871092:G>A" "KCNE1" "NM_001270404:c.-51+12307C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs767231003" "This variant is a VUS because it does not have enough information."
491150 "chr21:35871125:G>A" "KCNE1" "NM_001270404:c.-51+12274C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs375735858" "This variant is a VUS because it does not have enough information."
491151 "chr21:35871193:G>T" "KCNE1" "NM_001270404:c.-51+12206C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs545461689" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
491152 "chr21:35871196:C>T" "KCNE1" "NM_001270404:c.-51+12203G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs749172587" "This variant is a VUS because it does not have enough information."
491153 "chr21:35871197:G>A" "KCNE1" "NM_001270404:c.-51+12202C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs768585317" "This variant is a VUS because it does not have enough information."
491154 "chr21:35871228:C>T" "KCNE1" "NM_001270404:c.-51+12171G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs187987101" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491155 "chr21:35871235:T>C" "KCNE1" "NM_001270404:c.-51+12164A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs369910164" "This variant is a VUS because it does not have enough information."
491156 "chr21:35871286:C>T" "KCNE1" "NM_001270404:c.-51+12113G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs747915457" "This variant is a VUS because it does not have enough information."
491157 "chr21:35871291:C>A" "KCNE1" "NM_001270404:c.-51+12108G>T" "FIVE_PRIME_INTRON" "Benign" "rs56909293" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 27 1322 0.0204 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 29 5008 0.00579073
491158 "chr21:35871321:A>T" "KCNE1" "NM_001270404:c.-51+12078T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs112674430" "This variant is a VUS because it does not have enough information."
491159 "chr21:35871361:G>T" "KCNE1" "NM_001270404:c.-51+12038C>A" "FIVE_PRIME_INTRON" "Benign" "rs150016269" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 10 1008 0.0099 0 978 0 10 5008 0.00199681
491160 "chr21:35871379:C>T" "KCNE1" "NM_001270404:c.-51+12020G>A" "FIVE_PRIME_INTRON" "Benign" "rs7279771" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1211 1322 0.916 747 1006 0.7425 427 694 0.6153 404 1008 0.4008 799 978 0.817 3588 5008 0.716454
491161 "chr21:35871392:G>A" "KCNE1" "NM_001270404:c.-51+12007C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs776973018" "This variant is a VUS because it does not have enough information."
491162 "chr21:35871440:G>A" "KCNE1" "NM_001270404:c.-51+11959C>T" "FIVE_PRIME_INTRON" "Benign" "rs11701860" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 66 1322 0.0499 194 1006 0.1928 78 694 0.1124 2 1008 0.002 195 978 0.1994 535 5008 0.106829
491163 "chr21:35871444:G>T" "KCNE1" "NM_001270404:c.-51+11955C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs769760210" "This variant is a VUS because it does not have enough information."
491164 "chr21:35871464:A>C" "KCNE1" "NM_001270404:c.-51+11935T>G" "FIVE_PRIME_INTRON" "Benign" "rs115929259" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 28 1322 0.0212 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 29 5008 0.00579073
491165 "chr21:35871471:T>C" "KCNE1" "NM_001270404:c.-51+11928A>G" "FIVE_PRIME_INTRON" "Benign" "rs75765831" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 72 1322 0.0545 0 1006 0 3 694 0.0043 0 1008 0 0 978 0 75 5008 0.014976
491166 "chr21:35871491:C>T" "KCNE1" "NM_001270404:c.-51+11908G>A" "FIVE_PRIME_INTRON" "Benign" "rs531004983" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 6 1008 0.006 1 978 0.001 7 5008 0.00139776
491167 "chr21:35871519:C>T" "KCNE1" "NM_001270404:c.-51+11880G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs369462553" "This variant is a VUS because it does not have enough information."
491168 "chr21:35871528:T>C" "KCNE1" "NM_001270404:c.-51+11871A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs111696918" "This variant is a VUS because it does not have enough information."
491169 "chr21:35871602:G>A" "KCNE1" "NM_001270404:c.-51+11797C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs184136143" "This variant is a VUS because it does not have enough information." 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403
491170 "chr21:35871641:G>A" "KCNE1" "NM_001270404:c.-51+11758C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs762944135" "This variant is a VUS because it does not have enough information."
491171 "chr21:35871646:T>G" "KCNE1" "NM_001270404:c.-51+11753A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs74503860" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491172 "chr21:35871659:T>C" "KCNE1" "NM_001270404:c.-51+11740A>G" "FIVE_PRIME_INTRON" "Benign" "rs79968205" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 11 1322 0.0083 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 12 5008 0.00239617
491173 "chr21:35871667:T>C" "KCNE1" "NM_001270404:c.-51+11732A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs566826855" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491174 "chr21:35871667:T>A" "KCNE1" "NM_001270404:c.-51+11732A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs566826855" "This variant is a VUS because it does not have enough information."
491175 "chr21:35871672:T>C" "KCNE1" "NM_001270404:c.-51+11727A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs149089242" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 1 1006 0.001 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
491176 "chr21:35871720:C>T" "KCNE1" "NM_001270404:c.-51+11679G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs529000689" "This variant is a VUS because it does not have enough information." 6 1322 0.0045 0 1006 0 0 694 0 0 1008 0 1 978 0.001 7 5008 0.00139776
491177 "chr21:35871722:G>T" "KCNE1" "NM_001270404:c.-51+11677C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs372910261" "This variant is a VUS because it does not have enough information." 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042
491178 "chr21:35871722:G>A" "KCNE1" "NM_001270404:c.-51+11677C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs372910261" "This variant is a VUS because it does not have enough information."
491179 "chr21:35871735:A>G" "KCNE1" "NM_001270404:c.-51+11664T>C" "FIVE_PRIME_INTRON" "Benign" "rs74497317" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 71 1322 0.0537 54 1006 0.0537 23 694 0.0331 50 1008 0.0496 58 978 0.0593 256 5008 0.0511182
491180 "chr21:35871750:T>C" "KCNE1" "NM_001270404:c.-51+11649A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs539478033" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
491181 "chr21:35871836:G>A" "KCNE1" "NM_001270404:c.-51+11563C>T" "FIVE_PRIME_INTRON" "Benign" "rs565765413" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 9 1322 0.0068 0 1006 0 0 694 0 0 1008 0 0 978 0 9 5008 0.00179712
491182 "chr21:35871863:C>T" "KCNE1" "NM_001270404:c.-51+11536G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs533226897" "This variant is a VUS because it does not have enough information."
491183 "chr21:35871864:G>A" "KCNE1" "NM_001270404:c.-51+11535C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs551402908" "This variant is a VUS because it does not have enough information."
491184 "chr21:35871879:C>A" "KCNE1" "NM_001270404:c.-51+11520G>T" "FIVE_PRIME_INTRON" "Benign" "rs8134957" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 527 1322 0.3986 494 1006 0.4911 405 694 0.5836 797 1008 0.7907 533 978 0.545 2756 5008 0.550319
491185 "chr21:35871882:->G" "KCNE1" "NM_001270404:c.-51+11517_-51+11518insC" "FIVE_PRIME_INTRON" "Unknown significance" "rs35411468" "This variant is a VUS because it does not have enough information."
491186 "chr21:35871892:A>G" "KCNE1" "NM_001270404:c.-51+11507T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs141084201" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491187 "chr21:35871893:C>A" "KCNE1" "NM_001270404:c.-51+11506G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs555681443" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
491188 "chr21:35871925:T>C" "KCNE1" "NM_001270404:c.-51+11474A>G" "FIVE_PRIME_INTRON" "Benign" "rs115790929" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 32 1322 0.0242 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 33 5008 0.00658946
491189 "chr21:35871930:A>G" "KCNE1" "NM_001270404:c.-51+11469T>C" "FIVE_PRIME_INTRON" "Benign" "rs187627531" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 6 1008 0.006 0 978 0 6 5008 0.00119808
491190 "chr21:35871948:C>A" "KCNE1" "NM_001270404:c.-51+11451G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs765964782" "This variant is a VUS because it does not have enough information."
491191 "chr21:35871965:C>T" "KCNE1" "NM_001270404:c.-51+11434G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs562636552" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
491192 "chr21:35871966:G>A" "KCNE1" "NM_001270404:c.-51+11433C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs538248444" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 1 1006 0.001 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
491193 "chr21:35871983:G>A" "KCNE1" "NM_001270404:c.-51+11416C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs754481444" "This variant is a VUS because it does not have enough information."
491194 "chr21:35871989:T>C" "KCNE1" "NM_001270404:c.-51+11410A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs778946451" "This variant is a VUS because it does not have enough information."
491195 "chr21:35872000:G>A" "KCNE1" "NM_001270404:c.-51+11399C>T" "FIVE_PRIME_INTRON" "Benign" "rs146929277" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 9 1006 0.0089 2 694 0.0029 0 1008 0 1 978 0.001 12 5008 0.00239617
491196 "chr21:35872013:G>T" "KCNE1" "NM_001270404:c.-51+11386C>A" "FIVE_PRIME_INTRON" "Benign" "rs137956694" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 7 1322 0.0053 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 8 5008 0.00159744
491197 "chr21:35872021:C>T" "KCNE1" "NM_001270404:c.-51+11378G>A" "FIVE_PRIME_INTRON" "Benign" "rs13050900" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 328 1322 0.2481 298 1006 0.2962 323 694 0.4654 755 1008 0.749 278 978 0.2843 1982 5008 0.395767
491198 "chr21:35872058:T>G" "KCNE1" "NM_001270404:c.-51+11341A>C" "FIVE_PRIME_INTRON" "Benign" "rs141671164" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 8 1322 0.0061 0 1006 0 0 694 0 0 1008 0 0 978 0 8 5008 0.00159744
491199 "chr21:35872063:A>C" "KCNE1" "NM_001270404:c.-51+11336T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs562022837" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
491200 "chr21:35872097:G>A" "KCNE1" "NM_001270404:c.-51+11302C>T" "FIVE_PRIME_INTRON" "Benign" "rs115465060" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 16 1322 0.0121 0 1006 0 0 694 0 0 1008 0 0 978 0 16 5008 0.00319489
491201 "chr21:35872118:C>T" "KCNE1" "NM_001270404:c.-51+11281G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs192070412" "This variant is a VUS because it does not have enough information." 0 1322 0 3 1006 0.003 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042
491202 "chr21:35872134:T>C" "KCNE1" "NM_001270404:c.-51+11265A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs185641979" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 3 1008 0.003 0 978 0 3 5008 0.000599042
491203 "chr21:35872145:C>T" "KCNE1" "NM_001270404:c.-51+11254G>A" "FIVE_PRIME_INTRON" "Benign" "rs2409522" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 739 1322 0.559 499 1006 0.496 279 694 0.402 250 1008 0.248 504 978 0.5153 2271 5008 0.453474
491204 "chr21:35872146:G>A" "KCNE1" "NM_001270404:c.-51+11253C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs190500918" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
491205 "chr21:35872151:T>G" "KCNE1" "NM_001270404:c.-51+11248A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs775605702" "This variant is a VUS because it does not have enough information."
491206 "chr21:35872152:G>A" "KCNE1" "NM_001270404:c.-51+11247C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs566378591" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491207 "chr21:35872156:T>C" "KCNE1" "NM_001270404:c.-51+11243A>G" "FIVE_PRIME_INTRON" "Benign" "rs78331257" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 37 1322 0.028 0 1006 0 4 694 0.0058 0 1008 0 0 978 0 41 5008 0.0081869
491208 "chr21:35872158:G>A" "KCNE1" "NM_001270404:c.-51+11241C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs749339684" "This variant is a VUS because it does not have enough information."
491209 "chr21:35872170:A>G" "KCNE1" "NM_001270404:c.-51+11229T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs555371480" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491210 "chr21:35872294:T>C" "KCNE1" "NM_001270404:c.-51+11105A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs755718749" "This variant is a VUS because it does not have enough information."
491211 "chr21:35872304:G>A" "KCNE1" "NM_001270404:c.-51+11095C>T" "FIVE_PRIME_INTRON" "Benign" "rs116496071" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 30 1322 0.0227 1 1006 0.001 4 694 0.0058 0 1008 0 0 978 0 35 5008 0.00698882
491212 "chr21:35872363:C>T" "KCNE1" "NM_001270404:c.-51+11036G>A" "FIVE_PRIME_INTRON" "Benign" "rs8127146" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 715 1322 0.5408 494 1006 0.4911 414 694 0.5965 797 1008 0.7907 533 978 0.545 2953 5008 0.589657
491213 "chr21:35872392:T>-" "KCNE1" "NM_001270404:c.-51+11007delA" "FIVE_PRIME_INTRON" "Unknown significance" "rs528543897" "This variant is a VUS because it does not have enough information." 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042
491214 "chr21:35872496:C>T" "KCNE1" "NM_001270404:c.-51+10903G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs556397927" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
491215 "chr21:35872525:C>G" "KCNE1" "NM_001270404:c.-51+10874G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs577767307" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
491216 "chr21:35872536:T>C" "KCNE1" "NM_001270404:c.-51+10863A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs371223623" "This variant is a VUS because it does not have enough information."
491217 "chr21:35872568:C>T" "KCNE1" "NM_001270404:c.-51+10831G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs762371240" "This variant is a VUS because it does not have enough information."
491218 "chr21:35872609:T>G" "KCNE1" "NM_001270404:c.-51+10790A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs546023503" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
491219 "chr21:35872618:A>G" "KCNE1" "NM_001270404:c.-51+10781T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs767852470" "This variant is a VUS because it does not have enough information."
491220 "chr21:35872633:C>A" "KCNE1" "NM_001270404:c.-51+10766G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs773510129" "This variant is a VUS because it does not have enough information."
491221 "chr21:35872637:C>A" "KCNE1" "NM_001270404:c.-51+10762G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs760954589" "This variant is a VUS because it does not have enough information."
491222 "chr21:35872717:A>T" "KCNE1" "NM_001270404:c.-51+10682T>A" "FIVE_PRIME_INTRON" "Benign" "rs192364739" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 8 1322 0.0061 0 1006 0 0 694 0 0 1008 0 0 978 0 8 5008 0.00159744
491223 "chr21:35872724:C>G" "KCNE1" "NM_001270404:c.-51+10675G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs766019115" "This variant is a VUS because it does not have enough information."
491224 "chr21:35872751:C>A" "KCNE1" "NM_001270404:c.-51+10648G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs184267976" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491225 "chr21:35872786:C>A" "KCNE1" "NM_001270404:c.-51+10613G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs540254240" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 2 5008 0.000399361
491226 "chr21:35872803:T>C" "KCNE1" "NM_001270404:c.-51+10596A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs376066521" "This variant is a VUS because it does not have enough information."
491227 "chr21:35872808:T>C" "KCNE1" "NM_001270404:c.-51+10591A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs753458396" "This variant is a VUS because it does not have enough information."
491228 "chr21:35872851:T>G" "KCNE1" "NM_001270404:c.-51+10548A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs561714409" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491229 "chr21:35872875:C>A" "KCNE1" "NM_001270404:c.-51+10524G>T" "FIVE_PRIME_INTRON" "Benign" "rs7280165" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 98 1322 0.0741 0 1006 0 4 694 0.0058 0 1008 0 0 978 0 102 5008 0.0203674
491230 "chr21:35872878:C>T" "KCNE1" "NM_001270404:c.-51+10521G>A" "FIVE_PRIME_INTRON" "Benign" "rs138253425" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 16 1322 0.0121 0 1006 0 0 694 0 0 1008 0 0 978 0 16 5008 0.00319489
491231 "chr21:35872946:A>G" "KCNE1" "NM_001270404:c.-51+10453T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs188149502" "This variant is a VUS because it does not have enough information."
491232 "chr21:35873077:A>G" "KCNE1" "NM_001270404:c.-51+10322T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs572570873" "This variant is a VUS because it does not have enough information."
491233 "chr21:35873102:G>T" "KCNE1" "NM_001270404:c.-51+10297C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs562980849" "This variant is a VUS because it does not have enough information." 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042
491234 "chr21:35873110:T>C" "KCNE1" "NM_001270404:c.-51+10289A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs533555257" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491235 "chr21:35873129:T>C" "KCNE1" "NM_001270404:c.-51+10270A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs752679109" "This variant is a VUS because it does not have enough information."
491236 "chr21:35873144:T>C" "KCNE1" "NM_001270404:c.-51+10255A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs181340080" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 2 5008 0.000399361
491237 "chr21:35873158:A>G" "KCNE1" "NM_001270404:c.-51+10241T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs185419051" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 4 1008 0.004 0 978 0 4 5008 0.000798722
491238 "chr21:35873190:C>T" "KCNE1" "NM_001270404:c.-51+10209G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs533835648" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491239 "chr21:35873217:A>G" "KCNE1" "NM_001270404:c.-51+10182T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs371044192" "This variant is a VUS because it does not have enough information."
491240 "chr21:35873249:C>T" "KCNE1" "NM_001270404:c.-51+10150G>A" "FIVE_PRIME_INTRON" "Benign" "rs113600841" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 36 1322 0.0272 0 1006 0 4 694 0.0058 0 1008 0 0 978 0 40 5008 0.00798722
491241 "chr21:35873287:G>T" "KCNE1" "NM_001270404:c.-51+10112C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs149615196" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491242 "chr21:35873302:G>A" "KCNE1" "NM_001270404:c.-51+10097C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs538191285" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
491243 "chr21:35873304:C>T" "KCNE1" "NM_001270404:c.-51+10095G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs746776203" "This variant is a VUS because it does not have enough information."
491244 "chr21:35873326:C>T" "KCNE1" "NM_001270404:c.-51+10073G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs556417044" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491245 "chr21:35873357:A>G" "KCNE1" "NM_001270404:c.-51+10042T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs757025382" "This variant is a VUS because it does not have enough information."
491246 "chr21:35873375:G>A" "KCNE1" "NM_001270404:c.-51+10024C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs375522205" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
491247 "chr21:35873377:A>G" "KCNE1" "NM_001270404:c.-51+10022T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs146140678" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 4 1006 0.004 1 694 0.0014 0 1008 0 2 978 0.002 9 5008 0.00179712
491248 "chr21:35873381:G>C" "KCNE1" "NM_001270404:c.-51+10018C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs189011773" "This variant is a VUS because it does not have enough information."
491249 "chr21:35873392:C>T" "KCNE1" "NM_001270404:c.-51+10007G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs763329265" "This variant is a VUS because it does not have enough information."
491250 "chr21:35873424:G>A" "KCNE1" "NM_001270404:c.-51+9975C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs553658523" "This variant is a VUS because it does not have enough information." 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042
491251 "chr21:35873440:T>A" "KCNE1" "NM_001270404:c.-51+9959A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs573017588" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491252 "chr21:35873462:T>A" "KCNE1" "NM_001270404:c.-51+9937A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs540290048" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
491253 "chr21:35873497:G>A" "KCNE1" "NM_001270404:c.-51+9902C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs749508749" "This variant is a VUS because it does not have enough information."
491254 "chr21:35873502:G>A" "KCNE1" "NM_001270404:c.-51+9897C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs768715758" "This variant is a VUS because it does not have enough information."
491255 "chr21:35873509:T>C" "KCNE1" "NM_001270404:c.-51+9890A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs555387162" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
491256 "chr21:35873513:T>G" "KCNE1" "NM_001270404:c.-51+9886A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs572595292" "This variant is a VUS because it does not have enough information."
491257 "chr21:35873514:A>G" "KCNE1" "NM_001270404:c.-51+9885T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs558175287" "This variant is a VUS because it does not have enough information."
491258 "chr21:35873515:T>C" "KCNE1" "NM_001270404:c.-51+9884A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs573687772" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
491259 "chr21:35873520:A>C" "KCNE1" "NM_001270404:c.-51+9879T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs544538847" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491260 "chr21:35873530:A>G" "KCNE1" "NM_001270404:c.-51+9869T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs41314829" "This variant is a VUS because it does not have enough information." 4 1322 0.003 0 1006 0 0 694 0 0 1008 0 0 978 0 4 5008 0.000798722
491261 "chr21:35873541:C>T" "KCNE1" "NM_001270404:c.-51+9858G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs533428284" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491262 "chr21:35873550:T>G" "KCNE1" "NM_001270404:c.-51+9849A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs545595873" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 2 978 0.002 2 5008 0.000399361
491263 "chr21:35873567:A>T" "KCNE1" "NM_001270404:c.-51+9832T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs748243909" "This variant is a VUS because it does not have enough information."
491264 "chr21:35873569:T>C" "KCNE1" "NM_001270404:c.-51+9830A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs41315449" "This variant is a VUS because it does not have enough information."
491265 "chr21:35873573:T>A" "KCNE1" "NM_001270404:c.-51+9826A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs143949739" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491266 "chr21:35873589:A>G" "KCNE1" "NM_001270404:c.-51+9810T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs527382855" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
491267 "chr21:35873591:C>T" "KCNE1" "NM_001270404:c.-51+9808G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs75976902" "This variant is a VUS because it does not have enough information." 4 1322 0.003 0 1006 0 0 694 0 0 1008 0 0 978 0 4 5008 0.000798722
491268 "chr21:35873635:T>C" "KCNE1" "NM_001270404:c.-51+9764A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs41315451" "This variant is a VUS because it does not have enough information."
491269 "chr21:35873657:G>A" "KCNE1" "NM_001270404:c.-51+9742C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs41315453" "This variant is a VUS because it does not have enough information."
491270 "chr21:35873658:C>T" "KCNE1" "NM_001270404:c.-51+9741G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs76999537" "This variant is a VUS because it does not have enough information." 6 1322 0.0045 0 1006 0 0 694 0 0 1008 0 0 978 0 6 5008 0.00119808
491271 "chr21:35873684:T>C" "KCNE1" "NM_001270404:c.-51+9715A>G" "FIVE_PRIME_INTRON" "Benign" "rs41315455" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 13 1008 0.0129 0 978 0 13 5008 0.00259585
491272 "chr21:35873694:G>A" "KCNE1" "NM_001270404:c.-51+9705C>T" "FIVE_PRIME_INTRON" "Benign" "rs41314831" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 17 1322 0.0129 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 19 5008 0.00379393
491273 "chr21:35873700:T>C" "KCNE1" "NM_001270404:c.-51+9699A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs772504556" "This variant is a VUS because it does not have enough information."
491274 "chr21:35873701:T>C" "KCNE1" "NM_001270404:c.-51+9698A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs773627538" "This variant is a VUS because it does not have enough information."
491275 "chr21:35873716:G>T" "KCNE1" "NM_001270404:c.-51+9683C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs575944713" "This variant is a VUS because it does not have enough information."
491276 "chr21:35873779:T>C" "KCNE1" "NM_001270404:c.-51+9620A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs75099194" "This variant is a VUS because it does not have enough information."
491277 "chr21:35873791:C>T" "KCNE1" "NM_001270404:c.-51+9608G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs571539751" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
491278 "chr21:35873794:T>A" "KCNE1" "NM_001270404:c.-51+9605A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs538523915" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
491279 "chr21:35873843:C>T" "KCNE1" "NM_001270404:c.-51+9556G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs553943037" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
491280 "chr21:35873881:C>-" "KCNE1" "NM_001270404:c.-51+9518delG" "FIVE_PRIME_INTRON" "Unknown significance" "rs773853588" "This variant is a VUS because it does not have enough information."
491281 "chr21:35873920:->T" "KCNE1" "NM_001270404:c.-51+9479_-51+9480insA" "FIVE_PRIME_INTRON" "Benign" "rs202187506" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 5 694 0.0072 39 1008 0.0387 1 978 0.001 45 5008 0.00898562
491282 "chr21:35873924:T>G" "KCNE1" "NM_001270404:c.-51+9475A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs535590744" "This variant is a VUS because it does not have enough information."
491283 "chr21:35873951:C>A" "KCNE1" "NM_001270404:c.-51+9448G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs543009605" "This variant is a VUS because it does not have enough information."
491284 "chr21:35873951:C>T" "KCNE1" "NM_001270404:c.-51+9448G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs543009605" "This variant is a VUS because it does not have enough information."
491285 "chr21:35873961:A>G" "KCNE1" "NM_001270404:c.-51+9438T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs41314833" "This variant is a VUS because it does not have enough information."
491286 "chr21:35873989:G>T" "KCNE1" "NM_001270404:c.-51+9410C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs761054951" "This variant is a VUS because it does not have enough information."
491287 "chr21:35873992:T>G" "KCNE1" "NM_001270404:c.-51+9407A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs771251107" "This variant is a VUS because it does not have enough information."
491288 "chr21:35874019:A>G" "KCNE1" "NM_001270404:c.-51+9380T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs776316383" "This variant is a VUS because it does not have enough information."
491289 "chr21:35874035:C>T" "KCNE1" "NM_001270404:c.-51+9364G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs565533603" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 1 978 0.001 2 5008 0.000399361
491290 "chr21:35874074:A>-" "KCNE1" "NM_001270404:c.-51+9325delT" "FIVE_PRIME_INTRON" "Unknown significance" "rs768155080" "This variant is a VUS because it does not have enough information."
491291 "chr21:35874078:T>C" "KCNE1" "NM_001270404:c.-51+9321A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs534171270" "This variant is a VUS because it does not have enough information." 6 1322 0.0045 0 1006 0 0 694 0 0 1008 0 0 978 0 6 5008 0.00119808
491292 "chr21:35874124:C>T" "KCNE1" "NM_001270404:c.-51+9275G>A" "FIVE_PRIME_INTRON" "Benign" "rs16991742" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 2 1006 0.002 34 694 0.049 102 1008 0.1012 42 978 0.0429 180 5008 0.0359425
491293 "chr21:35874137:G>A" "KCNE1" "NM_001270404:c.-51+9262C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs573724862" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
491294 "chr21:35874142:A>G" "KCNE1" "NM_001270404:c.-51+9257T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs187208991" "This variant is a VUS because it does not have enough information."
491295 "chr21:35874149:A>G" "KCNE1" "NM_001270404:c.-51+9250T>C" "FIVE_PRIME_INTRON" "Benign" "rs2834498" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 66 1322 0.0499 194 1006 0.1928 78 694 0.1124 2 1008 0.002 195 978 0.1994 535 5008 0.106829
491296 "chr21:35874185:A>G" "KCNE1" "NM_001270404:c.-51+9214T>C" "FIVE_PRIME_INTRON" "Benign" "rs41314835" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 11 1322 0.0083 0 1006 0 0 694 0 0 1008 0 0 978 0 11 5008 0.00219649
491297 "chr21:35874208:G>C" "KCNE1" "NM_001270404:c.-51+9191C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs367646720" "This variant is a VUS because it does not have enough information."
491298 "chr21:35874209:T>C" "KCNE1" "NM_001270404:c.-51+9190A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs764074215" "This variant is a VUS because it does not have enough information."
491299 "chr21:35874213:C>T" "KCNE1" "NM_001270404:c.-51+9186G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs751499233" "This variant is a VUS because it does not have enough information."
491300 "chr21:35874231:G>T" "KCNE1" "NM_001270404:c.-51+9168C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs372309616" "This variant is a VUS because it does not have enough information."
491301 "chr21:35874278:C>A" "KCNE1" "NM_001270404:c.-51+9121G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs146294776" "This variant is a VUS because it does not have enough information." 0 1322 0 3 1006 0.003 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042
491302 "chr21:35874315:G>A" "KCNE1" "NM_001270404:c.-51+9084C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs71329071" "This variant is a VUS because it does not have enough information."
491303 "chr21:35874345:G>C" "KCNE1" "NM_001270404:c.-51+9054C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs780911450" "This variant is a VUS because it does not have enough information."
491304 "chr21:35874367:T>C" "KCNE1" "NM_001270404:c.-51+9032A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs545328127" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
491305 "chr21:35874413:T>C" "KCNE1" "NM_001270404:c.-51+8986A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs148516238" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491306 "chr21:35874414:T>A" "KCNE1" "NM_001270404:c.-51+8985A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs527881686" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
491307 "chr21:35874509:A>G" "KCNE1" "NM_001270404:c.-51+8890T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs542780315" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491308 "chr21:35874527:C>T" "KCNE1" "NM_001270404:c.-51+8872G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs375487479" "This variant is a VUS because it does not have enough information."
491309 "chr21:35874607:G>A" "KCNE1" "NM_001270404:c.-51+8792C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs560946584" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
491310 "chr21:35874686:C>A" "KCNE1" "NM_001270404:c.-51+8713G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs531406777" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
491311 "chr21:35874702:C>T" "KCNE1" "NM_001270404:c.-51+8697G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs754075958" "This variant is a VUS because it does not have enough information."
491312 "chr21:35874753:C>A" "KCNE1" "NM_001270404:c.-51+8646G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs549765800" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491313 "chr21:35874754:A>G" "KCNE1" "NM_001270404:c.-51+8645T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs755131992" "This variant is a VUS because it does not have enough information."
491314 "chr21:35874772:C>T" "KCNE1" "NM_001270404:c.-51+8627G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs571116673" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
491315 "chr21:35874828:C>T" "KCNE1" "NM_001270404:c.-51+8571G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs779114826" "This variant is a VUS because it does not have enough information."
491316 "chr21:35874829:G>A" "KCNE1" "NM_001270404:c.-51+8570C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs532441797" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
491317 "chr21:35874830:T>C" "KCNE1" "NM_001270404:c.-51+8569A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs528940031" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491318 "chr21:35874850:A>G" "KCNE1" "NM_001270404:c.-51+8549T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs765350887" "This variant is a VUS because it does not have enough information."
491319 "chr21:35874872:C>A" "KCNE1" "NM_001270404:c.-51+8527G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs778324702" "This variant is a VUS because it does not have enough information."
491320 "chr21:35874876:A>G" "KCNE1" "NM_001270404:c.-51+8523T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs565572207" "This variant is a VUS because it does not have enough information." 6 1322 0.0045 0 1006 0 0 694 0 0 1008 0 0 978 0 6 5008 0.00119808
491321 "chr21:35874884:C>T" "KCNE1" "NM_001270404:c.-51+8515G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs536016914" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
491322 "chr21:35874911:A>G" "KCNE1" "NM_001270404:c.-51+8488T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs547952991" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
491323 "chr21:35874913:C>T" "KCNE1" "NM_001270404:c.-51+8486G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs567433419" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491324 "chr21:35874934:A>G" "KCNE1" "NM_001270404:c.-51+8465T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs11702021" "This variant is a VUS because it does not have enough information."
491325 "chr21:35874952:A>T" "KCNE1" "NM_001270404:c.-51+8447T>A" "FIVE_PRIME_INTRON" "Benign" "rs192092387" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 8 1008 0.0079 0 978 0 8 5008 0.00159744
491326 "chr21:35874977:G>A" "KCNE1" "NM_001270404:c.-51+8422C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs775736100" "This variant is a VUS because it does not have enough information."
491327 "chr21:35874989:G>T" "KCNE1" "NM_001270404:c.-51+8410C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs747511002" "This variant is a VUS because it does not have enough information."
491328 "chr21:35874994:G>A" "KCNE1" "NM_001270404:c.-51+8405C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs556521601" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491329 "chr21:35875000:T>-" "KCNE1" "NM_001270404:c.-51+8399delA" "FIVE_PRIME_INTRON" "Unknown significance" "rs778562708" "This variant is a VUS because it does not have enough information."
491330 "chr21:35875008:C>T" "KCNE1" "NM_001270404:c.-51+8391G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs577954047" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 1 1008 0.001 0 978 0 2 5008 0.000399361
491331 "chr21:35875058:G>A" "KCNE1" "NM_001270404:c.-51+8341C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs771323208" "This variant is a VUS because it does not have enough information."
491332 "chr21:35875100:A>C" "KCNE1" "NM_001270404:c.-51+8299T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs539361464" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
491333 "chr21:35875102:C>A" "KCNE1" "NM_001270404:c.-51+8297G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs554491805" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
491334 "chr21:35875107:G>A" "KCNE1" "NM_001270404:c.-51+8292C>T" "FIVE_PRIME_INTRON" "Benign" "rs183845286" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 5 1006 0.005 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403
491335 "chr21:35875111:C>T" "KCNE1" "NM_001270404:c.-51+8288G>A" "FIVE_PRIME_INTRON" "Benign" "rs115774149" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 14 1322 0.0106 0 1006 0 0 694 0 0 1008 0 0 978 0 14 5008 0.00279553
491336 "chr21:35875113:->ACACTCTTT" "KCNE1" "NM_001270404:c.-51+8286_-51+8287insAAAGAGTGT" "FIVE_PRIME_INTRON" "Unknown significance" "rs567494040" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 4 1008 0.004 0 978 0 4 5008 0.000798722
491337 "chr21:35875119:TTT>-" "KCNE1" "NM_001270404:c.-51+8280_-51+8284delAAA" "FIVE_PRIME_INTRON" "Unknown significance" "rs745486020" "This variant is a VUS because it does not have enough information."
491338 "chr21:35875149:T>A" "KCNE1" "NM_001270404:c.-51+8250A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs764206945" "This variant is a VUS because it does not have enough information."
491339 "chr21:35875152:C>G" "KCNE1" "NM_001270404:c.-51+8247G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs759994362" "This variant is a VUS because it does not have enough information."
491340 "chr21:35875167:G>A" "KCNE1" "NM_001270404:c.-51+8232C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs769530604" "This variant is a VUS because it does not have enough information."
491341 "chr21:35875171:A>C" "KCNE1" "NM_001270404:c.-51+8228T>G" "FIVE_PRIME_INTRON" "Benign" "rs151068424" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 16 1322 0.0121 0 1006 0 0 694 0 0 1008 0 0 978 0 16 5008 0.00319489
491342 "chr21:35875198:A>G" "KCNE1" "NM_001270404:c.-51+8201T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs576098603" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
491343 "chr21:35875206:G>A" "KCNE1" "NM_001270404:c.-51+8193C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs532993256" "This variant is a VUS because it does not have enough information."
491344 "chr21:35875240:C>T" "KCNE1" "NM_001270404:c.-51+8159G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs551606560" "This variant is a VUS because it does not have enough information."
491345 "chr21:35875263:->T" "KCNE1" "NM_001270404:c.-51+8136_-51+8137insA" "FIVE_PRIME_INTRON" "Unknown significance" "rs34415334" "This variant is a VUS because it does not have enough information."
491346 "chr21:35875286:->GTATCA" "KCNE1" "NM_001270404:c.-51+8113_-51+8114insTGATAC" "FIVE_PRIME_INTRON" "Unknown significance" "rs751704702" "This variant is a VUS because it does not have enough information."
491347 "chr21:35875292:G>C" "KCNE1" "NM_001270404:c.-51+8107C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs140806029" "This variant is a VUS because it does not have enough information." 3 1322 0.0023 0 1006 0 0 694 0 0 1008 0 0 978 0 3 5008 0.000599042
491348 "chr21:35875329:T>G" "KCNE1" "NM_001270404:c.-51+8070A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs757827908" "This variant is a VUS because it does not have enough information."
491349 "chr21:35875353:T>C" "KCNE1" "NM_001270404:c.-51+8046A>G" "FIVE_PRIME_INTRON" "Benign" "rs144421769" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 1 1322 0.0008 9 1006 0.0089 4 694 0.0058 0 1008 0 44 978 0.045 58 5008 0.0115815
491350 "chr21:35875360:C>A" "KCNE1" "NM_001270404:c.-51+8039G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs531996340" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 2 978 0.002 2 5008 0.000399361
491351 "chr21:35875386:G>A" "KCNE1" "NM_001270404:c.-51+8013C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs762529645" "This variant is a VUS because it does not have enough information."
491352 "chr21:35875415:C>T" "KCNE1" "NM_001270404:c.-51+7984G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs547698275" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
491353 "chr21:35875451:C>A" "KCNE1" "NM_001270404:c.-51+7948G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs559244843" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
491354 "chr21:35875494:C>A" "KCNE1" "NM_001270404:c.-51+7905G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs763552043" "This variant is a VUS because it does not have enough information."
491355 "chr21:35875503:T>C" "KCNE1" "NM_001270404:c.-51+7896A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs751506836" "This variant is a VUS because it does not have enough information."
491356 "chr21:35875521:T>A" "KCNE1" "NM_001270404:c.-51+7878A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs113466746" "This variant is a VUS because it does not have enough information." 5 1322 0.0038 0 1006 0 0 694 0 0 1008 0 0 978 0 5 5008 0.000998403
491357 "chr21:35875538:T>C" "KCNE1" "NM_001270404:c.-51+7861A>G" "FIVE_PRIME_INTRON" "Benign" "rs376301815" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 5 1008 0.005 0 978 0 5 5008 0.000998403
491358 "chr21:35875561:T>C" "KCNE1" "NM_001270404:c.-51+7838A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs569463060" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
491359 "chr21:35875568:C>T" "KCNE1" "NM_001270404:c.-51+7831G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs761711534" "This variant is a VUS because it does not have enough information."
491360 "chr21:35875584:T>C" "KCNE1" "NM_001270404:c.-51+7815A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs538380999" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
491361 "chr21:35875587:C>T" "KCNE1" "NM_001270404:c.-51+7812G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs549999518" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
491362 "chr21:35875606:C>T" "KCNE1" "NM_001270404:c.-51+7793G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs186242355" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 1 978 0.001 2 5008 0.000399361
491363 "chr21:35875639:G>C" "KCNE1" "NM_001270404:c.-51+7760C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs767499770" "This variant is a VUS because it does not have enough information."
491364 "chr21:35875675:C>A" "KCNE1" "NM_001270404:c.-51+7724G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs538636606" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491365 "chr21:35875692:C>G" "KCNE1" "NM_001270404:c.-51+7707G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs750122321" "This variant is a VUS because it does not have enough information."
491366 "chr21:35875717:C>T" "KCNE1" "NM_001270404:c.-51+7682G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs147835497" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
491367 "chr21:35875723:C>T" "KCNE1" "NM_001270404:c.-51+7676G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs755937024" "This variant is a VUS because it does not have enough information."
491368 "chr21:35875729:C>A" "KCNE1" "NM_001270404:c.-51+7670G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs189782395" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491369 "chr21:35875759:A>T" "KCNE1" "NM_001270404:c.-51+7640T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs530869200" "This variant is a VUS because it does not have enough information."
491370 "chr21:35875794:A>T" "KCNE1" "NM_001270404:c.-51+7605T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs536906271" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491371 "chr21:35875794:A>G" "KCNE1" "NM_001270404:c.-51+7605T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs536906271" "This variant is a VUS because it does not have enough information."
491372 "chr21:35875804:C>T" "KCNE1" "NM_001270404:c.-51+7595G>A" "FIVE_PRIME_INTRON" "Benign" "rs116809235" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 32 1322 0.0242 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 33 5008 0.00658946
491373 "chr21:35875824:C>G" "KCNE1" "NM_001270404:c.-51+7575G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs576560052" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
491374 "chr21:35875827:G>C" "KCNE1" "NM_001270404:c.-51+7572C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs182775895" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491375 "chr21:35875843:G>A" "KCNE1" "NM_001270404:c.-51+7556C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs564805431" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 2 5008 0.000399361
491376 "chr21:35875852:C>T" "KCNE1" "NM_001270404:c.-51+7547G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs141437816" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491377 "chr21:35875855:A>G" "KCNE1" "NM_001270404:c.-51+7544T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs758442888" "This variant is a VUS because it does not have enough information."
491378 "chr21:35875863:A>G" "KCNE1" "NM_001270404:c.-51+7536T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs147017622" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
491379 "chr21:35875867:A>G" "KCNE1" "NM_001270404:c.-51+7532T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs560606629" "This variant is a VUS because it does not have enough information."
491380 "chr21:35875876:T>G" "KCNE1" "NM_001270404:c.-51+7523A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs11700430" "This variant is a VUS because it does not have enough information."
491381 "chr21:35875884:C>T" "KCNE1" "NM_001270404:c.-51+7515G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs550185731" "This variant is a VUS because it does not have enough information."
491382 "chr21:35875935:A>G" "KCNE1" "NM_001270404:c.-51+7464T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs558879322" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
491383 "chr21:35875940:C>T" "KCNE1" "NM_001270404:c.-51+7459G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs369423864" "This variant is a VUS because it does not have enough information."
491384 "chr21:35875942:T>C" "KCNE1" "NM_001270404:c.-51+7457A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs529938329" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491385 "chr21:35875944:C>T" "KCNE1" "NM_001270404:c.-51+7455G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs568497330" "This variant is a VUS because it does not have enough information."
491386 "chr21:35875953:C>T" "KCNE1" "NM_001270404:c.-51+7446G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs535922794" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
491387 "chr21:35875962:C>T" "KCNE1" "NM_001270404:c.-51+7437G>A" "FIVE_PRIME_INTRON" "Benign" "rs563537067" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 0 1008 0 7 978 0.0072 7 5008 0.00139776
491388 "chr21:35875979:A>G" "KCNE1" "NM_001270404:c.-51+7420T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs187064282" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491389 "chr21:35875983:C>G" "KCNE1" "NM_001270404:c.-51+7416G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs137889153" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
491390 "chr21:35875986:G>A" "KCNE1" "NM_001270404:c.-51+7413C>T" "FIVE_PRIME_INTRON" "Benign" "rs79096492" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 108 1322 0.0817 0 1006 0 4 694 0.0058 0 1008 0 0 978 0 112 5008 0.0223642
491391 "chr21:35876026:T>C" "KCNE1" "NM_001270404:c.-51+7373A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs532606720" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 3 978 0.0031 3 5008 0.000599042
491392 "chr21:35876035:T>G" "KCNE1" "NM_001270404:c.-51+7364A>C" "FIVE_PRIME_INTRON" "Benign" "rs192223934" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 10 1322 0.0076 0 1006 0 0 694 0 0 1008 0 0 978 0 10 5008 0.00199681
491393 "chr21:35876089:C>T" "KCNE1" "NM_001270404:c.-51+7310G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs757648580" "This variant is a VUS because it does not have enough information."
491394 "chr21:35876098:C>T" "KCNE1" "NM_001270404:c.-51+7301G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs566033944" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
491395 "chr21:35876099:T>C" "KCNE1" "NM_001270404:c.-51+7300A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs536993568" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
491396 "chr21:35876130:G>C" "KCNE1" "NM_001270404:c.-51+7269C>G" "FIVE_PRIME_INTRON" "Benign" "rs2834499" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 88 1322 0.0666 0 1006 0 5 694 0.0072 0 1008 0 0 978 0 93 5008 0.0185703
491397 "chr21:35876137:G>T" "KCNE1" "NM_001270404:c.-51+7262C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs570258447" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 4 978 0.0041 4 5008 0.000798722
491398 "chr21:35876161:C>T" "KCNE1" "NM_001270404:c.-51+7238G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs781737247" "This variant is a VUS because it does not have enough information."
491399 "chr21:35876169:C>T" "KCNE1" "NM_001270404:c.-51+7230G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs746184645" "This variant is a VUS because it does not have enough information."
491400 "chr21:35876176:C>G" "KCNE1" "NM_001270404:c.-51+7223G>C" "FIVE_PRIME_INTRON" "Benign" "rs183498380" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 11 1008 0.0109 0 978 0 11 5008 0.00219649
491401 "chr21:35876199:G>A" "KCNE1" "NM_001270404:c.-51+7200C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs143064908" "This variant is a VUS because it does not have enough information." 4 1322 0.003 0 1006 0 0 694 0 0 1008 0 1 978 0.001 5 5008 0.000998403
491402 "chr21:35876205:C>T" "KCNE1" "NM_001270404:c.-51+7194G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs188792413" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 1 694 0.0014 0 1008 0 0 978 0 2 5008 0.000399361
491403 "chr21:35876211:G>T" "KCNE1" "NM_001270404:c.-51+7188C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs775251847" "This variant is a VUS because it does not have enough information."
491404 "chr21:35876215:A>C" "KCNE1" "NM_001270404:c.-51+7184T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs540676265" "This variant is a VUS because it does not have enough information." 4 1322 0.003 0 1006 0 0 694 0 0 1008 0 0 978 0 4 5008 0.000798722
491405 "chr21:35876242:C>T" "KCNE1" "NM_001270404:c.-51+7157G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs552595189" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
491406 "chr21:35876267:C>T" "KCNE1" "NM_001270404:c.-51+7132G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs749011676" "This variant is a VUS because it does not have enough information."
491407 "chr21:35876281:T>G" "KCNE1" "NM_001270404:c.-51+7118A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs574083840" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
491408 "chr21:35876294:->C" "KCNE1" "NM_001270404:c.-51+7105_-51+7106insG" "FIVE_PRIME_INTRON" "Unknown significance" "rs34721313" "This variant is a VUS because it does not have enough information."
491409 "chr21:35876294:C>T" "KCNE1" "NM_001270404:c.-51+7105G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs768195057" "This variant is a VUS because it does not have enough information."
491410 "chr21:35876299:A>G" "KCNE1" "NM_001270404:c.-51+7100T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs541758875" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491411 "chr21:35876304:C>A" "KCNE1" "NM_001270404:c.-51+7095G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs563415418" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 2 5008 0.000399361
491412 "chr21:35876312:C>G" "KCNE1" "NM_001270404:c.-51+7087G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs530808396" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
491413 "chr21:35876340:C>A" "KCNE1" "NM_001270404:c.-51+7059G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs545698326" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491414 "chr21:35876397:T>C" "KCNE1" "NM_001270404:c.-51+7002A>G" "FIVE_PRIME_INTRON" "Benign" "rs564266927" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 10 1322 0.0076 0 1006 0 0 694 0 0 1008 0 0 978 0 10 5008 0.00199681
491415 "chr21:35876411:G>A" "KCNE1" "NM_001270404:c.-51+6988C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs566221690" "This variant is a VUS because it does not have enough information."
491416 "chr21:35876415:C>T" "KCNE1" "NM_001270404:c.-51+6984G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs367730934" "This variant is a VUS because it does not have enough information."
491417 "chr21:35876427:C>A" "KCNE1" "NM_001270404:c.-51+6972G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs532655859" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491418 "chr21:35876438:C>T" "KCNE1" "NM_001270404:c.-51+6961G>A" "FIVE_PRIME_INTRON" "Benign" "rs2051391" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 66 1322 0.0499 194 1006 0.1928 78 694 0.1124 2 1008 0.002 196 978 0.2004 536 5008 0.107029
491419 "chr21:35876446:A>G" "KCNE1" "NM_001270404:c.-51+6953T>C" "FIVE_PRIME_INTRON" "Benign" "rs16991747" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 137 1322 0.1036 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 139 5008 0.0277556
491420 "chr21:35876458:C>T" "KCNE1" "NM_001270404:c.-51+6941G>A" "FIVE_PRIME_INTRON" "Benign" "rs16991751" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 84 1322 0.0635 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 86 5008 0.0171725
491421 "chr21:35876460:G>A" "KCNE1" "NM_001270404:c.-51+6939C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs548573011" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
491422 "chr21:35876486:C>T" "KCNE1" "NM_001270404:c.-51+6913G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs148222522" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 1 978 0.001 2 5008 0.000399361
491423 "chr21:35876520:G>A" "KCNE1" "NM_001270404:c.-51+6879C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs537708943" "This variant is a VUS because it does not have enough information." 6 1322 0.0045 0 1006 0 0 694 0 0 1008 0 0 978 0 6 5008 0.00119808
491424 "chr21:35876638:G>C" "KCNE1" "NM_001270404:c.-51+6761C>G" "FIVE_PRIME_INTRON" "Benign" "rs79435473" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 24 1322 0.0182 0 1006 0 0 694 0 0 1008 0 0 978 0 24 5008 0.00479233
491425 "chr21:35876662:C>A" "KCNE1" "NM_001270404:c.-51+6737G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs571019823" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491426 "chr21:35876688:C>G" "KCNE1" "NM_001270404:c.-51+6711G>C" "FIVE_PRIME_INTRON" "Benign" "rs76811300" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 137 1322 0.1036 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 139 5008 0.0277556
491427 "chr21:35876692:G>A" "KCNE1" "NM_001270404:c.-51+6707C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs552632802" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491428 "chr21:35876698:C>G" "KCNE1" "NM_001270404:c.-51+6701G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs773157988" "This variant is a VUS because it does not have enough information."
491429 "chr21:35876722:G>A" "KCNE1" "NM_001270404:c.-51+6677C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs368749503" "This variant is a VUS because it does not have enough information."
491430 "chr21:35876737:G>A" "KCNE1" "NM_001270404:c.-51+6662C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs780314281" "This variant is a VUS because it does not have enough information."
491431 "chr21:35876750:C>T" "KCNE1" "NM_001270404:c.-51+6649G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs574125359" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
491432 "chr21:35876758:C>T" "KCNE1" "NM_001270404:c.-51+6641G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs753463003" "This variant is a VUS because it does not have enough information."
491433 "chr21:35876780:C>T" "KCNE1" "NM_001270404:c.-51+6619G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs372185992" "This variant is a VUS because it does not have enough information."
491434 "chr21:35876785:C>A" "KCNE1" "NM_001270404:c.-51+6614G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs760445182" "This variant is a VUS because it does not have enough information."
491435 "chr21:35876836:G>A" "KCNE1" "NM_001270404:c.-51+6563C>T" "FIVE_PRIME_INTRON" "Benign" "rs73365387" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 17 1322 0.0129 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 19 5008 0.00379393
491436 "chr21:35876865:C>G" "KCNE1" "NM_001270404:c.-51+6534G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs766206136" "This variant is a VUS because it does not have enough information."
491437 "chr21:35876894:A>G" "KCNE1" "NM_001270404:c.-51+6505T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs556885089" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
491438 "chr21:35876947:C>A" "KCNE1" "NM_001270404:c.-51+6452G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs575462428" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
491439 "chr21:35876971:G>T" "KCNE1" "NM_001270404:c.-51+6428C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs752911695" "This variant is a VUS because it does not have enough information."
491440 "chr21:35876974:C>T" "KCNE1" "NM_001270404:c.-51+6425G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs546034613" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491441 "chr21:35876978:C>G" "KCNE1" "NM_001270404:c.-51+6421G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs569111313" "This variant is a VUS because it does not have enough information."
491442 "chr21:35876981:A>C" "KCNE1" "NM_001270404:c.-51+6418T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs758679008" "This variant is a VUS because it does not have enough information."
491443 "chr21:35877027:A>G" "KCNE1" "NM_001270404:c.-51+6372T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs764391597" "This variant is a VUS because it does not have enough information."
491444 "chr21:35877028:A>G" "KCNE1" "NM_001270404:c.-51+6371T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs564175545" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491445 "chr21:35877036:T>C" "KCNE1" "NM_001270404:c.-51+6363A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs754638044" "This variant is a VUS because it does not have enough information."
491446 "chr21:35877039:T>C" "KCNE1" "NM_001270404:c.-51+6360A>G" "FIVE_PRIME_INTRON" "Benign" "rs56088739" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 58 1322 0.0439 0 1006 0 4 694 0.0058 0 1008 0 0 978 0 62 5008 0.0123802
491447 "chr21:35877088:C>T" "KCNE1" "NM_001270404:c.-51+6311G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs141225191" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491448 "chr21:35877090:A>T" "KCNE1" "NM_001270404:c.-51+6309T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs751529597" "This variant is a VUS because it does not have enough information."
491449 "chr21:35877109:T>C" "KCNE1" "NM_001270404:c.-51+6290A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs757378619" "This variant is a VUS because it does not have enough information."
491450 "chr21:35877127:T>C" "KCNE1" "NM_001270404:c.-51+6272A>G" "FIVE_PRIME_INTRON" "Benign" "rs555427933" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 0 1008 0 17 978 0.0174 17 5008 0.00339457
491451 "chr21:35877152:T>C" "KCNE1" "NM_001270404:c.-51+6247A>G" "FIVE_PRIME_INTRON" "Benign" "rs145107549" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 13 1322 0.0098 0 1006 0 0 694 0 0 1008 0 0 978 0 13 5008 0.00259585
491452 "chr21:35877195:C>T" "KCNE1" "NM_001270404:c.-51+6204G>A" "FIVE_PRIME_INTRON" "Benign" "rs59152183" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 37 1322 0.028 46 1006 0.0457 39 694 0.0562 90 1008 0.0893 91 978 0.093 303 5008 0.0605032
491453 "chr21:35877196:G>A" "KCNE1" "NM_001270404:c.-51+6203C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs375151144" "This variant is a VUS because it does not have enough information." 3 1322 0.0023 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 4 5008 0.000798722
491454 "chr21:35877237:A>C" "KCNE1" "NM_001270404:c.-51+6162T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs193301472" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491455 "chr21:35877240:G>A" "KCNE1" "NM_001270404:c.-51+6159C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs552824832" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
491456 "chr21:35877260:G>A" "KCNE1" "NM_001270404:c.-51+6139C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs570744472" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491457 "chr21:35877275:T>C" "KCNE1" "NM_001270404:c.-51+6124A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs780618568" "This variant is a VUS because it does not have enough information."
491458 "chr21:35877286:G>A" "KCNE1" "NM_001270404:c.-51+6113C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs554915707" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 1 1006 0.001 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
491459 "chr21:35877306:C>G" "KCNE1" "NM_001270404:c.-51+6093G>C" "FIVE_PRIME_INTRON" "Benign" "rs546763766" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 0 1008 0 7 978 0.0072 7 5008 0.00139776
491460 "chr21:35877349:C>T" "KCNE1" "NM_001270404:c.-51+6050G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs767713469" "This variant is a VUS because it does not have enough information."
491461 "chr21:35877350:G>A" "KCNE1" "NM_001270404:c.-51+6049C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs567831746" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
491462 "chr21:35877355:G>A" "KCNE1" "NM_001270404:c.-51+6044C>T" "FIVE_PRIME_INTRON" "Benign" "rs74377027" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 108 1322 0.0817 0 1006 0 4 694 0.0058 0 1008 0 0 978 0 112 5008 0.0223642
491463 "chr21:35877359:A>G" "KCNE1" "NM_001270404:c.-51+6040T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs556689744" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491464 "chr21:35877432:->TATT" "KCNE1" "NM_001270404:c.-51+5967_-51+5968insAATA" "FIVE_PRIME_INTRON" "Unknown significance" "rs534044632" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 3 5008 0.000599042
491465 "chr21:35877448:T>G" "KCNE1" "NM_001270404:c.-51+5951A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs747720525" "This variant is a VUS because it does not have enough information."
491466 "chr21:35877473:C>T" "KCNE1" "NM_001270404:c.-51+5926G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs377742044" "This variant is a VUS because it does not have enough information."
491467 "chr21:35877527:G>A" "KCNE1" "NM_001270404:c.-51+5872C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs575196666" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361
491468 "chr21:35877580:C>T" "KCNE1" "NM_001270404:c.-51+5819G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs747565901" "This variant is a VUS because it does not have enough information."
491469 "chr21:35877581:G>A" "KCNE1" "NM_001270404:c.-51+5818C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs573317429" "This variant is a VUS because it does not have enough information."
491470 "chr21:35877592:C>T" "KCNE1" "NM_001270404:c.-51+5807G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs371140134" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 1 978 0.001 2 5008 0.000399361
491471 "chr21:35877599:T>C" "KCNE1" "NM_001270404:c.-51+5800A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs375803899" "This variant is a VUS because it does not have enough information."
491472 "chr21:35877621:T>C" "KCNE1" "NM_001270404:c.-51+5778A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs558018666" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491473 "chr21:35877664:C>A" "KCNE1" "NM_001270404:c.-51+5735G>T" "FIVE_PRIME_INTRON" "Benign" "rs112953491" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 37 1322 0.028 0 1006 0 4 694 0.0058 0 1008 0 0 978 0 41 5008 0.0081869
491474 "chr21:35877684:C>T" "KCNE1" "NM_001270404:c.-51+5715G>A" "FIVE_PRIME_INTRON" "Benign" "rs62211550" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 75 1322 0.0567 194 1006 0.1928 78 694 0.1124 2 1008 0.002 195 978 0.1994 544 5008 0.108626
491475 "chr21:35877685:G>C" "KCNE1" "NM_001270404:c.-51+5714C>G" "FIVE_PRIME_INTRON" "Benign" "rs188300409" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 11 1008 0.0109 0 978 0 11 5008 0.00219649
491476 "chr21:35877712:C>T" "KCNE1" "NM_001270404:c.-51+5687G>A" "FIVE_PRIME_INTRON" "Benign" "rs74658406" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 16 1322 0.0121 53 1006 0.0527 22 694 0.0317 69 1008 0.0685 60 978 0.0613 220 5008 0.0439297
491477 "chr21:35877743:C>-" "KCNE1" "NM_001270404:c.-51+5656delG" "FIVE_PRIME_INTRON" "Benign" "rs576654608" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 29 1322 0.0219 0 1006 0 0 694 0 0 1008 0 0 978 0 29 5008 0.00579073
491478 "chr21:35877745:->T" "KCNE1" "NM_001270404:c.-51+5654_-51+5655insA" "FIVE_PRIME_INTRON" "Unknown significance" "rs376734609" "This variant is a VUS because it does not have enough information."
491479 "chr21:35877758:A>G" "KCNE1" "NM_001270404:c.-51+5641T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs542306178" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 1 978 0.001 3 5008 0.000599042
491480 "chr21:35877772:G>A" "KCNE1" "NM_001270404:c.-51+5627C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs563572246" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491481 "chr21:35877784:T>C" "KCNE1" "NM_001270404:c.-51+5615A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs766150442" "This variant is a VUS because it does not have enough information."
491482 "chr21:35877796:G>A" "KCNE1" "NM_001270404:c.-51+5603C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs776354185" "This variant is a VUS because it does not have enough information."
491483 "chr21:35877807:G>A" "KCNE1" "NM_001270404:c.-51+5592C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs538415258" "This variant is a VUS because it does not have enough information."
491484 "chr21:35877830:G>A" "KCNE1" "NM_001270404:c.-51+5569C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs530918094" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
491485 "chr21:35877839:A>C" "KCNE1" "NM_001270404:c.-51+5560T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs191204727" "This variant is a VUS because it does not have enough information."
491486 "chr21:35877860:C>T" "KCNE1" "NM_001270404:c.-51+5539G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs759381423" "This variant is a VUS because it does not have enough information."
491487 "chr21:35877863:G>A" "KCNE1" "NM_001270404:c.-51+5536C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs776995479" "This variant is a VUS because it does not have enough information."
491488 "chr21:35877879:A>G" "KCNE1" "NM_001270404:c.-51+5520T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs751855010" "This variant is a VUS because it does not have enough information."
491489 "chr21:35877899:G>C" "KCNE1" "NM_001270404:c.-51+5500C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs552621035" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491490 "chr21:35877921:G>A" "KCNE1" "NM_001270404:c.-51+5478C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs142228146" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
491491 "chr21:35877924:CAGGCC>-" "KCNE1" "NM_001270404:c.-51+5475_-51+5482delGGCCTG" "FIVE_PRIME_INTRON" "Unknown significance" "rs746946549" "This variant is a VUS because it does not have enough information."
491492 "chr21:35877957:C>T" "KCNE1" "NM_001270404:c.-51+5442G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs528727405" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 2 978 0.002 2 5008 0.000399361
491493 "chr21:35877988:G>T" "KCNE1" "NM_001270404:c.-51+5411C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs146397742" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 2 5008 0.000399361
491494 "chr21:35878029:A>T" "KCNE1" "NM_001270404:c.-51+5370T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs568268206" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
491495 "chr21:35878030:C>T" "KCNE1" "NM_001270404:c.-51+5369G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs757252449" "This variant is a VUS because it does not have enough information."
491496 "chr21:35878052:C>T" "KCNE1" "NM_001270404:c.-51+5347G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs535245899" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491497 "chr21:35878055:C>T" "KCNE1" "NM_001270404:c.-51+5344G>A" "FIVE_PRIME_INTRON" "Benign" "rs77084628" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 27 1322 0.0204 0 1006 0 2 694 0.0029 0 1008 0 0 978 0 29 5008 0.00579073
491498 "chr21:35878092:C>T" "KCNE1" "NM_001270404:c.-51+5307G>A" "FIVE_PRIME_INTRON" "Benign" "rs16991753" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 41 1322 0.031 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 42 5008 0.00838658
491499 "chr21:35878096:A>G" "KCNE1" "NM_001270404:c.-51+5303T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs374637436" "This variant is a VUS because it does not have enough information."
491500 "chr21:35878100:A>T" "KCNE1" "NM_001270404:c.-51+5299T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs367968235" "This variant is a VUS because it does not have enough information."
491501 "chr21:35878120:G>T" "KCNE1" "NM_001270404:c.-51+5279C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs780708365" "This variant is a VUS because it does not have enough information."
491502 "chr21:35878130:A>T" "KCNE1" "NM_001270404:c.-51+5269T>A" "FIVE_PRIME_INTRON" "Benign" "rs79100931" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 108 1322 0.0817 0 1006 0 4 694 0.0058 0 1008 0 0 978 0 112 5008 0.0223642
491503 "chr21:35878148:C>T" "KCNE1" "NM_001270404:c.-51+5251G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs533096819" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 1 978 0.001 2 5008 0.000399361
491504 "chr21:35878193:G>T" "KCNE1" "NM_001270404:c.-51+5206C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs184079604" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 3 1008 0.003 0 978 0 3 5008 0.000599042
491505 "chr21:35878235:G>A" "KCNE1" "NM_001270404:c.-51+5164C>T" "FIVE_PRIME_INTRON" "Benign" "rs139237502" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 7 1008 0.0069 0 978 0 7 5008 0.00139776
491506 "chr21:35878239:T>C" "KCNE1" "NM_001270404:c.-51+5160A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs188373025" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 2 1008 0.002 0 978 0 2 5008 0.000399361
491507 "chr21:35878254:A>G" "KCNE1" "NM_001270404:c.-51+5145T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs80053978" "This variant is a VUS because it does not have enough information."
491508 "chr21:35878272:A>G" "KCNE1" "NM_001270404:c.-51+5127T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs573869976" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
491509 "chr21:35878276:T>G" "KCNE1" "NM_001270404:c.-51+5123A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs41315459" "This variant is a VUS because it does not have enough information."
491510 "chr21:35878309:C>T" "KCNE1" "NM_001270404:c.-51+5090G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs62211551" "This variant is a VUS because it does not have enough information."
491511 "chr21:35878310:G>C" "KCNE1" "NM_001270404:c.-51+5089C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs778410163" "This variant is a VUS because it does not have enough information."
491512 "chr21:35878320:G>A" "KCNE1" "NM_001270404:c.-51+5079C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs575127034" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
491513 "chr21:35878339:C>T" "KCNE1" "NM_001270404:c.-51+5060G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs747878968" "This variant is a VUS because it does not have enough information."
491514 "chr21:35878340:G>A" "KCNE1" "NM_001270404:c.-51+5059C>T" "FIVE_PRIME_INTRON" "Benign" "rs563779689" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 0 1006 0 0 694 0 0 1008 0 21 978 0.0215 21 5008 0.00419329
491515 "chr21:35878353:A>C" "KCNE1" "NM_001270404:c.-51+5046T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs369573301" "This variant is a VUS because it does not have enough information."
491516 "chr21:35878381:C>A" "KCNE1" "NM_001270404:c.-51+5018G>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs544867745" "This variant is a VUS because it does not have enough information."
491517 "chr21:35878385:A>G" "KCNE1" "NM_001270404:c.-51+5014T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs575623097" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 1 5008 0.000199681
491518 "chr21:35878426:C>T" "KCNE1" "NM_001270404:c.-51+4973G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs770722575" "This variant is a VUS because it does not have enough information."
491519 "chr21:35878427:A>G" "KCNE1" "NM_001270404:c.-51+4972T>C" "FIVE_PRIME_INTRON" "Benign" "rs41314837" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 12 1322 0.0091 0 1006 0 0 694 0 0 1008 0 0 978 0 12 5008 0.00239617
491520 "chr21:35878492:G>A" "KCNE1" "NM_001270404:c.-51+4907C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs77125347" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
491521 "chr21:35878493:C>T" "KCNE1" "NM_001270404:c.-51+4906G>A" "FIVE_PRIME_INTRON" "Benign" "rs41314839" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 15 1322 0.0113 0 1006 0 0 694 0 0 1008 0 0 978 0 15 5008 0.00299521
491522 "chr21:35878506:G>A" "KCNE1" "NM_001270404:c.-51+4893C>T" "FIVE_PRIME_INTRON" "Benign" "rs41312997" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 14 1006 0.0139 6 694 0.0086 0 1008 0 2 978 0.002 22 5008 0.00439297
491523 "chr21:35878519:C>T" "KCNE1" "NM_001270404:c.-51+4880G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs549317595" "This variant is a VUS because it does not have enough information."
491524 "chr21:35878521:C>T" "KCNE1" "NM_001270404:c.-51+4878G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs770789005" "This variant is a VUS because it does not have enough information."
491525 "chr21:35878536:G>A" "KCNE1" "NM_001270404:c.-51+4863C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs181762720" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491526 "chr21:35878546:T>G" "KCNE1" "NM_001270404:c.-51+4853A>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs41315461" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 3 1008 0.003 0 978 0 3 5008 0.000599042
491527 "chr21:35878566:G>A" "KCNE1" "NM_001270404:c.-51+4833C>T" "FIVE_PRIME_INTRON" "Benign" "rs41314841" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 7 1322 0.0053 0 1006 0 0 694 0 0 1008 0 0 978 0 7 5008 0.00139776
491528 "chr21:35878568:C>T" "KCNE1" "NM_001270404:c.-51+4831G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs568947889" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
491529 "chr21:35878589:C>T" "KCNE1" "NM_001270404:c.-51+4810G>A" "FIVE_PRIME_INTRON" "Benign" "rs41314843" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 16 1322 0.0121 0 1006 0 0 694 0 0 1008 0 0 978 0 16 5008 0.00319489
491530 "chr21:35878592:C>T" "KCNE1" "NM_001270404:c.-51+4807G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs769058844" "This variant is a VUS because it does not have enough information."
491531 "chr21:35878605:T>C" "KCNE1" "NM_001270404:c.-51+4794A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs187146032" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491532 "chr21:35878620:C>G" "KCNE1" "NM_001270404:c.-51+4779G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs74783163" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
491533 "chr21:35878635:A>G" "KCNE1" "NM_001270404:c.-51+4764T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs189980645" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
491534 "chr21:35878645:C>G" "KCNE1" "NM_001270404:c.-51+4754G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs555683466" "This variant is a VUS because it does not have enough information." 2 1322 0.0015 0 1006 0 0 694 0 0 1008 0 0 978 0 2 5008 0.000399361
491535 "chr21:35878677:G>C" "KCNE1" "NM_001270404:c.-51+4722C>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs567376521" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
491536 "chr21:35878715:G>A" "KCNE1" "NM_001270404:c.-51+4684C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs79974834" "This variant is a VUS because it does not have enough information."
491537 "chr21:35878724:G>A" "KCNE1" "NM_001270404:c.-51+4675C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs538065091" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
491538 "chr21:35878776:->C" "KCNE1" "NM_001270404:c.-51+4623_-51+4624insG" "FIVE_PRIME_INTRON" "Unknown significance" "rs71324308" "This variant is a VUS because it does not have enough information."
491539 "chr21:35878798:G>A" "KCNE1" "NM_001270404:c.-51+4601C>T" "FIVE_PRIME_INTRON" "Benign" "rs114493655" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 11 1322 0.0083 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 12 5008 0.00239617
491540 "chr21:35878820:C>T" "KCNE1" "NM_001270404:c.-51+4579G>A" "FIVE_PRIME_INTRON" "Benign" "rs117091871" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 0 1322 0 8 1006 0.008 0 694 0 0 1008 0 0 978 0 8 5008 0.00159744
491541 "chr21:35878869:C>A" "KCNE1" "NM_001270404:c.-51+4530G>T" "FIVE_PRIME_INTRON" "Benign" "rs182503217" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 18 1322 0.0136 0 1006 0 0 694 0 0 1008 0 0 978 0 18 5008 0.00359425
491542 "chr21:35878885:C>G" "KCNE1" "NM_001270404:c.-51+4514G>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs373614621" "This variant is a VUS because it does not have enough information."
491543 "chr21:35878891:C>T" "KCNE1" "NM_001270404:c.-51+4508G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs557777798" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 1 978 0.001 2 5008 0.000399361
491544 "chr21:35878896:A>T" "KCNE1" "NM_001270404:c.-51+4503T>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs529312622" "This variant is a VUS because it does not have enough information."
491545 "chr21:35878906:G>A" "KCNE1" "NM_001270404:c.-51+4493C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs368635101" "This variant is a VUS because it does not have enough information."
491546 "chr21:35878964:T>C" "KCNE1" "NM_001270404:c.-51+4435A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs572895780" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 2 978 0.002 2 5008 0.000399361
491547 "chr21:35879014:A>G" "KCNE1" "NM_001270404:c.-51+4385T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs759228296" "This variant is a VUS because it does not have enough information."
491548 "chr21:35879067:C>T" "KCNE1" "NM_001270404:c.-51+4332G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs540562596" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
491549 "chr21:35879089:G>T" "KCNE1" "NM_001270404:c.-51+4310C>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs562024863" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491550 "chr21:35879091:G>A" "KCNE1" "NM_001270404:c.-51+4308C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs769668896" "This variant is a VUS because it does not have enough information."
491551 "chr21:35879102:C>T" "KCNE1" "NM_001270404:c.-51+4297G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs529525499" "This variant is a VUS because it does not have enough information." 0 1322 0 1 1006 0.001 1 694 0.0014 0 1008 0 0 978 0 2 5008 0.000399361
491552 "chr21:35879116:G>A" "KCNE1" "NM_001270404:c.-51+4283C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs547821558" "This variant is a VUS because it does not have enough information."
491553 "chr21:35879128:T>C" "KCNE1" "NM_001270404:c.-51+4271A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs762152197" "This variant is a VUS because it does not have enough information."
491554 "chr21:35879133:T>A" "KCNE1" "NM_001270404:c.-51+4266A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs41312999" "This variant is a VUS because it does not have enough information." 0 1322 0 4 1006 0.004 0 694 0 0 1008 0 2 978 0.002 6 5008 0.00119808
491555 "chr21:35879170:T>A" "KCNE1" "NM_001270404:c.-51+4229A>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs562891008" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 1 1008 0.001 0 978 0 1 5008 0.000199681
491556 "chr21:35879183:C>T" "KCNE1" "NM_001270404:c.-51+4216G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs186390889" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491557 "chr21:35879186:T>C" "KCNE1" "NM_001270404:c.-51+4213A>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs750458566" "This variant is a VUS because it does not have enough information."
491558 "chr21:35879208:A>C" "KCNE1" "NM_001270404:c.-51+4191T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs75411094" "This variant is a VUS because it does not have enough information."
491559 "chr21:35879218:G>A" "KCNE1" "NM_001270404:c.-51+4181C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs551491624" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491560 "chr21:35879239:A>G" "KCNE1" "NM_001270404:c.-51+4160T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs537649892" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
491561 "chr21:35879268:C>T" "KCNE1" "NM_001270404:c.-51+4131G>A" "FIVE_PRIME_INTRON" "Benign" "rs41315463" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 228 1322 0.1725 54 1006 0.0537 30 694 0.0432 50 1008 0.0496 58 978 0.0593 420 5008 0.0838658
491562 "chr21:35879271:A>G" "KCNE1" "NM_001270404:c.-51+4128T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs766947015" "This variant is a VUS because it does not have enough information."
491563 "chr21:35879272:T>C" "KCNE1" "NM_001270404:c.-51+4127A>G" "FIVE_PRIME_INTRON" "Benign" "rs41315345" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 70 1322 0.053 0 1006 0 3 694 0.0043 0 1008 0 0 978 0 73 5008 0.0145767
491564 "chr21:35879277:C>T" "KCNE1" "NM_001270404:c.-51+4122G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs79565233" "This variant is a VUS because it does not have enough information." 4 1322 0.003 0 1006 0 0 694 0 0 1008 0 0 978 0 4 5008 0.000798722
491565 "chr21:35879295:C>T" "KCNE1" "NM_001270404:c.-51+4104G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs41315465" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 3 694 0.0043 0 1008 0 0 978 0 3 5008 0.000599042
491566 "chr21:35879296:G>A" "KCNE1" "NM_001270404:c.-51+4103C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs556327208" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
491567 "chr21:35879320:C>T" "KCNE1" "NM_001270404:c.-51+4079G>A" "FIVE_PRIME_INTRON" "Unknown significance" "rs551666442" "This variant is a VUS because it does not have enough information."
491568 "chr21:35879345:G>A" "KCNE1" "NM_001270404:c.-51+4054C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs757988887" "This variant is a VUS because it does not have enough information."
491569 "chr21:35879350:T>G" "KCNE1" "NM_001270404:c.-51+4049A>C" "FIVE_PRIME_INTRON" "Benign" "rs16991754" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 41 1322 0.031 0 1006 0 1 694 0.0014 0 1008 0 0 978 0 42 5008 0.00838658
491570 "chr21:35879357:A>C" "KCNE1" "NM_001270404:c.-51+4042T>G" "FIVE_PRIME_INTRON" "Unknown significance" "rs539587587" "This variant is a VUS because it does not have enough information." 0 1322 0 0 1006 0 0 694 0 0 1008 0 1 978 0.001 1 5008 0.000199681
491571 "chr21:35879382:C>T" "KCNE1" "NM_001270404:c.-51+4017G>A" "FIVE_PRIME_INTRON" "Benign" "rs41315467" "This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005." 75 1322 0.0567 54 1006 0.0537 23 694 0.0331 50 1008 0.0496 58 978 0.0593 260 5008 0.0519169
491572 "chr21:35879397:A>G" "KCNE1" "NM_001270404:c.-51+4002T>C" "FIVE_PRIME_INTRON" "Unknown significance" "rs572932452" "This variant is a VUS because it does not have enough information." 1 1322 0.0008 0 1006 0 0 694 0 0 1008 0 0 978 0 1 5008 0.000199681
491573 "chr21:35879413:G>A" "KCNE1" "NM_001270404:c.-51+3986C>T" "FIVE_PRIME_INTRON" "Unknown significance" "rs371156653" "This variant is a VUS because it does not have enough information."