id,variation,gene,hgvs_protein_change,hgvs_nucleotide_change,variantlocale,pathogenicity,disease,pubmed_id,dbsnp,summary_insilico,summary_frequency,summary_published,comments,lrt_omega,phylop_score,phylop_pred,sift_score,sift_pred,polyphen2_score,polyphen2_pred,lrt_score,lrt_pred,mutationtaster_score,mutationtaster_pred,gerp_nr,gerp_rs,gerp_pred,evs_ea_ac,evs_ea_an,evs_ea_af,evs_aa_ac,evs_aa_an,evs_aa_af,evs_all_ac,evs_all_an,evs_all_af,otoscope_aj_ac,otoscope_aj_an,otoscope_aj_af,otoscope_co_ac,otoscope_co_an,otoscope_co_af,otoscope_us_ac,otoscope_us_an,otoscope_us_af,otoscope_jp_ac,otoscope_jp_an,otoscope_jp_af,otoscope_es_ac,otoscope_es_an,otoscope_es_af,otoscope_tr_ac,otoscope_tr_an,otoscope_tr_af,otoscope_all_ac,otoscope_all_an,otoscope_all_af,tg_afr_ac,tg_afr_an,tg_afr_af,tg_eur_ac,tg_eur_an,tg_eur_af,tg_amr_ac,tg_amr_an,tg_amr_af,tg_eas_ac,tg_eas_an,tg_eas_af,tg_sas_ac,tg_sas_an,tg_sas_af,tg_all_ac,tg_all_an,tg_all_af,exac_afr_ac,exac_afr_an,exac_afr_af,exac_amr_ac,exac_amr_an,exac_amr_af,exac_eas_ac,exac_eas_an,exac_eas_af,exac_fin_ac,exac_fin_an,exac_fin_af,exac_nfe_ac,exac_nfe_an,exac_nfe_af,exac_oth_ac,exac_oth_an,exac_oth_af,exac_sas_ac,exac_sas_an,exac_sas_af,exac_all_ac,exac_all_an,exac_all_af
416016,"chr19:10332109:A>T","S1PR2",,"NM_004230:c.*2411T>A","THREE_PRIME_EXON","Unknown significance",,,"rs770223204",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416017,"chr19:10332123:C>A","S1PR2",,"NM_004230:c.*2397G>T","THREE_PRIME_EXON","Unknown significance",,,"rs558518703",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,1,978,0.001,2,5008,0.000399361,,,,,,,,,,,,,,,,,,,,,,,,
416018,"chr19:10332124:G>A","S1PR2",,"NM_004230:c.*2396C>T","THREE_PRIME_EXON","Unknown significance",,,"rs149404755",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,2,1006,0.002,1,694,0.0014,0,1008,0,1,978,0.001,4,5008,0.000798722,,,,,,,,,,,,,,,,,,,,,,,,
416019,"chr19:10332129:T>C","S1PR2",,"NM_004230:c.*2391A>G","THREE_PRIME_EXON","Unknown significance",,,"rs778103329",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416020,"chr19:10332137:G>A","S1PR2",,"NM_004230:c.*2383C>T","THREE_PRIME_EXON","Unknown significance",,,"rs143790225",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,5,1322,0.0038,0,1006,0,0,694,0,0,1008,0,0,978,0,5,5008,0.000998403,,,,,,,,,,,,,,,,,,,,,,,,
416021,"chr19:10332165:C>T","S1PR2",,"NM_004230:c.*2355G>A","THREE_PRIME_EXON","Unknown significance",,,"rs377146753",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416022,"chr19:10332217:C>G","S1PR2",,"NM_004230:c.*2303G>C","THREE_PRIME_EXON","Unknown significance",,,"rs79481092",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416023,"chr19:10332226:C>T","S1PR2",,"NM_004230:c.*2294G>A","THREE_PRIME_EXON","Unknown significance",,,"rs777849554",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416024,"chr19:10332257:T>G","S1PR2",,"NM_004230:c.*2263A>C","THREE_PRIME_EXON","Unknown significance",,,"rs73015122",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,4,1006,0.004,0,694,0,0,1008,0,1,978,0.001,5,5008,0.000998403,,,,,,,,,,,,,,,,,,,,,,,,
416025,"chr19:10332273:G>A","S1PR2",,"NM_004230:c.*2247C>T","THREE_PRIME_EXON","Unknown significance",,,"rs542021716",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416026,"chr19:10332328:C>A","S1PR2",,"NM_004230:c.*2192G>T","THREE_PRIME_EXON","Unknown significance",,,"rs563677819",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416027,"chr19:10332340:G>A","S1PR2",,"NM_004230:c.*2180C>T","THREE_PRIME_EXON","Unknown significance",,,"rs111640725",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416028,"chr19:10332357:A>G","S1PR2",,"NM_004230:c.*2163T>C","THREE_PRIME_EXON","Unknown significance",,,"rs575682796",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,4,1008,0.004,0,978,0,4,5008,0.000798722,,,,,,,,,,,,,,,,,,,,,,,,
416029,"chr19:10332364:C>T","S1PR2",,"NM_004230:c.*2156G>A","THREE_PRIME_EXON","Unknown significance",,,"rs545886602",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,1,978,0.001,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416030,"chr19:10332391:G>A","S1PR2",,"NM_004230:c.*2129C>T","THREE_PRIME_EXON","Unknown significance",,,"rs564458518",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,1,978,0.001,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416031,"chr19:10332417:G>A","S1PR2",,"NM_004230:c.*2103C>T","THREE_PRIME_EXON","Unknown significance",,,"rs781399611",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416032,"chr19:10332429:C>T","S1PR2",,"NM_004230:c.*2091G>A","THREE_PRIME_EXON","Unknown significance",,,"rs528782647",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,2,1008,0.002,0,978,0,3,5008,0.000599042,,,,,,,,,,,,,,,,,,,,,,,,
416033,"chr19:10332430:G>T","S1PR2",,"NM_004230:c.*2090C>A","THREE_PRIME_EXON","Unknown significance",,,"rs368234473",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416034,"chr19:10332455:C>T","S1PR2",,"NM_004230:c.*2065G>A","THREE_PRIME_EXON","Unknown significance",,,"rs746075189",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416035,"chr19:10332456:G>A","S1PR2",,"NM_004230:c.*2064C>T","THREE_PRIME_EXON","Benign",,,"rs115321277",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,33,1322,0.025,0,1006,0,0,694,0,0,1008,0,0,978,0,33,5008,0.00658946,,,,,,,,,,,,,,,,,,,,,,,,
416036,"chr19:10332470:G>A","S1PR2",,"NM_004230:c.*2050C>T","THREE_PRIME_EXON","Unknown significance",,,"rs147346249",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416037,"chr19:10332471:C>T","S1PR2",,"NM_004230:c.*2049G>A","THREE_PRIME_EXON","Unknown significance",,,"rs546472499",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416038,"chr19:10332473:C>T","S1PR2",,"NM_004230:c.*2047G>A","THREE_PRIME_EXON","Unknown significance",,,"rs372293542",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,2,978,0.002,2,5008,0.000399361,,,,,,,,,,,,,,,,,,,,,,,,
416039,"chr19:10332474:G>A","S1PR2",,"NM_004230:c.*2046C>T","THREE_PRIME_EXON","Unknown significance",,,"rs76167553",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,2,1008,0.002,1,978,0.001,3,5008,0.000599042,,,,,,,,,,,,,,,,,,,,,,,,
416040,"chr19:10332478:G>A","S1PR2",,"NM_004230:c.*2042C>T","THREE_PRIME_EXON","Unknown significance",,,"rs551152975",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,4,1322,0.003,0,1006,0,0,694,0,0,1008,0,1,978,0.001,5,5008,0.000998403,,,,,,,,,,,,,,,,,,,,,,,,
416041,"chr19:10332487:T>C","S1PR2",,"NM_004230:c.*2033A>G","THREE_PRIME_EXON","Unknown significance",,,"rs775855539",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416042,"chr19:10332488:->AC","S1PR2",,"NM_004230:c.*2032_*2033insGT","THREE_PRIME_EXON","Unknown significance",,,"rs777202046",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416043,"chr19:10332489:->AC","S1PR2",,"NM_004230:c.*2031_*2032insGT","THREE_PRIME_EXON","Unknown significance",,,"rs372070428",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416044,"chr19:10332511:C>T","S1PR2",,"NM_004230:c.*2009G>A","THREE_PRIME_EXON","Benign",,,"rs139477595",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,46,1322,0.0348,0,1006,0,2,694,0.0029,0,1008,0,0,978,0,48,5008,0.00958466,,,,,,,,,,,,,,,,,,,,,,,,
416045,"chr19:10332547:T>A","S1PR2",,"NM_004230:c.*1973A>T","THREE_PRIME_EXON","Benign",,,"rs55818584",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,103,1322,0.0779,266,1006,0.2644,151,694,0.2176,86,1008,0.0853,125,978,0.1278,731,5008,0.145966,,,,,,,,,,,,,,,,,,,,,,,,
416046,"chr19:10332569:G>T","S1PR2",,"NM_004230:c.*1951C>A","THREE_PRIME_EXON","Unknown significance",,,"rs551891263",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416047,"chr19:10332574:->G","S1PR2",,"NM_004230:c.*1946_*1947insC","THREE_PRIME_EXON","Unknown significance",,,"rs34208381",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416048,"chr19:10332574:G>A","S1PR2",,"NM_004230:c.*1946C>T","THREE_PRIME_EXON","Benign",,,"rs570426482",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,5,978,0.0051,5,5008,0.000998403,,,,,,,,,,,,,,,,,,,,,,,,
416049,"chr19:10332582:T>C","S1PR2",,"NM_004230:c.*1938A>G","THREE_PRIME_EXON","Unknown significance",,,"rs771920403",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416050,"chr19:10332588:C>T","S1PR2",,"NM_004230:c.*1932G>A","THREE_PRIME_EXON","Unknown significance",,,"rs534582935",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,1,978,0.001,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416051,"chr19:10332617:C>G","S1PR2",,"NM_004230:c.*1903G>C","THREE_PRIME_EXON","Unknown significance",,,"rs577624437",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416052,"chr19:10332652:C>T","S1PR2",,"NM_004230:c.*1868G>A","THREE_PRIME_EXON","Unknown significance",,,"rs574780173",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416053,"chr19:10332664:C>A","S1PR2",,"NM_004230:c.*1856G>T","THREE_PRIME_EXON","Unknown significance",,,"rs535686311",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416054,"chr19:10332686:T>C","S1PR2",,"NM_004230:c.*1834A>G","THREE_PRIME_EXON","Unknown significance",,,"rs527414492",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416055,"chr19:10332696:C>T","S1PR2",,"NM_004230:c.*1824G>A","THREE_PRIME_EXON","Unknown significance",,,"rs773003554",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416056,"chr19:10332705:C>G","S1PR2",,"NM_004230:c.*1815G>C","THREE_PRIME_EXON","Unknown significance",,,"rs74178202",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416057,"chr19:10332706:G>A","S1PR2",,"NM_004230:c.*1814C>T","THREE_PRIME_EXON","Unknown significance",,,"rs143696275",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,3,1008,0.003,0,978,0,3,5008,0.000599042,,,,,,,,,,,,,,,,,,,,,,,,
416058,"chr19:10332715:G>T","S1PR2",,"NM_004230:c.*1805C>A","THREE_PRIME_EXON","Unknown significance",,,"rs188305573",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2,1322,0.0015,0,1006,0,0,694,0,0,1008,0,0,978,0,2,5008,0.000399361,,,,,,,,,,,,,,,,,,,,,,,,
416059,"chr19:10332743:C>T","S1PR2",,"NM_004230:c.*1777G>A","THREE_PRIME_EXON","Unknown significance",,,"rs147221266",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2,1322,0.0015,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,3,5008,0.000599042,,,,,,,,,,,,,,,,,,,,,,,,
416060,"chr19:10332746:C>T","S1PR2",,"NM_004230:c.*1774G>A","THREE_PRIME_EXON","Unknown significance",,,"rs35309986",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,1,1006,0.001,0,694,0,0,1008,0,0,978,0,2,5008,0.000399361,,,,,,,,,,,,,,,,,,,,,,,,
416061,"chr19:10332855:C>T","S1PR2",,"NM_004230:c.*1665G>A","THREE_PRIME_EXON","Unknown significance",,,"rs572936836",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416062,"chr19:10332932:A>-","S1PR2",,"NM_004230:c.*1588delT","THREE_PRIME_EXON","Unknown significance",,,"rs35699769",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416063,"chr19:10332957:T>C","S1PR2",,"NM_004230:c.*1563A>G","THREE_PRIME_EXON","Unknown significance",,,"rs139543274",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416064,"chr19:10332962:C>A","S1PR2",,"NM_004230:c.*1558G>T","THREE_PRIME_EXON","Benign",,,"rs114818137",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,24,1322,0.0182,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,25,5008,0.00499201,,,,,,,,,,,,,,,,,,,,,,,,
416065,"chr19:10332974:C>G","S1PR2",,"NM_004230:c.*1546G>C","THREE_PRIME_EXON","Unknown significance",,,"rs562092502",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,1,978,0.001,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416066,"chr19:10332988:C>T","S1PR2",,"NM_004230:c.*1532G>A","THREE_PRIME_EXON","Benign",,,"rs10409243",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,458,1322,0.3464,588,1006,0.5845,300,694,0.4323,244,1008,0.2421,515,978,0.5266,2105,5008,0.420327,,,,,,,,,,,,,,,,,,,,,,,,
416067,"chr19:10332992:G>A","S1PR2",,"NM_004230:c.*1528C>T","THREE_PRIME_EXON","Unknown significance",,,"rs776186056",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416068,"chr19:10333010:C>A","S1PR2",,"NM_004230:c.*1510G>T","THREE_PRIME_EXON","Unknown significance",,,"rs544490629",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416069,"chr19:10333012:C>T","S1PR2",,"NM_004230:c.*1508G>A","THREE_PRIME_EXON","Unknown significance",,,"rs563054244",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,4,1322,0.003,0,1006,0,0,694,0,0,1008,0,0,978,0,4,5008,0.000798722,,,,,,,,,,,,,,,,,,,,,,,,
416070,"chr19:10333020:G>A","S1PR2",,"NM_004230:c.*1500C>T","THREE_PRIME_EXON","Unknown significance",,,"rs759061285",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416071,"chr19:10333039:C>G","S1PR2",,"NM_004230:c.*1481G>C","THREE_PRIME_EXON","Unknown significance",,,"rs530532930",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416072,"chr19:10333046:A>-","S1PR2",,"NM_004230:c.*1474delT","THREE_PRIME_EXON","Unknown significance",,,"rs529718719",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,3,1006,0.003,0,694,0,0,1008,0,1,978,0.001,4,5008,0.000798722,,,,,,,,,,,,,,,,,,,,,,,,
416073,"chr19:10333047:G>A","S1PR2",,"NM_004230:c.*1473C>T","THREE_PRIME_EXON","Unknown significance",,,"rs764803767",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416074,"chr19:10333067:G>A","S1PR2",,"NM_004230:c.*1453C>T","THREE_PRIME_EXON","Unknown significance",,,"rs552280721",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416075,"chr19:10333099:G>A","S1PR2",,"NM_004230:c.*1421C>T","THREE_PRIME_EXON","Unknown significance",,,"rs752380059",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416076,"chr19:10333100:G>C","S1PR2",,"NM_004230:c.*1420C>G","THREE_PRIME_EXON","Unknown significance",,,"rs570538584",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416077,"chr19:10333134:A>G","S1PR2",,"NM_004230:c.*1386T>C","THREE_PRIME_EXON","Unknown significance",,,"rs758643828",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416078,"chr19:10333146:C>T","S1PR2",,"NM_004230:c.*1374G>A","THREE_PRIME_EXON","Unknown significance",,,"rs550099571",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416079,"chr19:10333163:G>A","S1PR2",,"NM_004230:c.*1357C>T","THREE_PRIME_EXON","Unknown significance",,,"rs528137879",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416080,"chr19:10333203:C>A","S1PR2",,"NM_004230:c.*1317G>T","THREE_PRIME_EXON","Unknown significance",,,"rs764557435",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416081,"chr19:10333204:A>G","S1PR2",,"NM_004230:c.*1316T>C","THREE_PRIME_EXON","Benign",,,"rs116016370",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,222,1322,0.1679,0,1006,0,7,694,0.0101,0,1008,0,0,978,0,229,5008,0.0457268,,,,,,,,,,,,,,,,,,,,,,,,
416082,"chr19:10333206:A>G","S1PR2",,"NM_004230:c.*1314T>C","THREE_PRIME_EXON","Unknown significance",,,"rs568371565",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,2,978,0.002,2,5008,0.000399361,,,,,,,,,,,,,,,,,,,,,,,,
416083,"chr19:10333247:T>C","S1PR2",,"NM_004230:c.*1273A>G","THREE_PRIME_EXON","Unknown significance",,,"rs535693204",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416084,"chr19:10333288:C>T","S1PR2",,"NM_004230:c.*1232G>A","THREE_PRIME_EXON","Unknown significance",,,"rs10415075",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416085,"chr19:10333342:C>T","S1PR2",,"NM_004230:c.*1178G>A","THREE_PRIME_EXON","Unknown significance",,,"rs757839210",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416086,"chr19:10333446:T>C","S1PR2",,"NM_004230:c.*1074A>G","THREE_PRIME_EXON","Benign",,,"rs75737111",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,4,1006,0.004,0,694,0,70,1008,0.0694,14,978,0.0143,88,5008,0.0175719,,,,,,,,,,,,,,,,,,,,,,,,
416087,"chr19:10333519:A>G","S1PR2",,"NM_004230:c.*1001T>C","THREE_PRIME_EXON","Unknown significance",,,"rs776323559",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416088,"chr19:10333572:T>C","S1PR2",,"NM_004230:c.*948A>G","THREE_PRIME_EXON","Unknown significance",,,"rs375839774",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416089,"chr19:10333575:G>A","S1PR2",,"NM_004230:c.*945C>T","THREE_PRIME_EXON","Unknown significance",,,"rs568999142",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416090,"chr19:10333604:C>T","S1PR2",,"NM_004230:c.*916G>A","THREE_PRIME_EXON","Benign",,,"rs185250322",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,24,1322,0.0182,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,25,5008,0.00499201,,,,,,,,,,,,,,,,,,,,,,,,
416091,"chr19:10333606:C>T","S1PR2",,"NM_004230:c.*914G>A","THREE_PRIME_EXON","Unknown significance",,,"rs558259993",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416092,"chr19:10333680:->A","S1PR2",,"NM_004230:c.*840_*841insT","THREE_PRIME_EXON","Benign",,,"rs558153089",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,208,1322,0.1573,226,1006,0.2247,203,694,0.2925,240,1008,0.2381,247,978,0.2526,1124,5008,0.224441,,,,,,,,,,,,,,,,,,,,,,,,
416093,"chr19:10333703:C>T","S1PR2",,"NM_004230:c.*817G>A","THREE_PRIME_EXON","Unknown significance",,,"rs572999098",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,4,1322,0.003,0,1006,0,0,694,0,0,1008,0,0,978,0,4,5008,0.000798722,,,,,,,,,,,,,,,,,,,,,,,,
416094,"chr19:10333704:G>A","S1PR2",,"NM_004230:c.*816C>T","THREE_PRIME_EXON","Unknown significance",,,"rs540272270",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416095,"chr19:10333707:G>A","S1PR2",,"NM_004230:c.*813C>T","THREE_PRIME_EXON","Benign",,,"rs555303276",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,9,1322,0.0068,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,10,5008,0.00199681,,,,,,,,,,,,,,,,,,,,,,,,
416096,"chr19:10333716:A>C","S1PR2",,"NM_004230:c.*804T>G","THREE_PRIME_EXON","Unknown significance",,,"rs144263589",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416097,"chr19:10333731:T>C","S1PR2",,"NM_004230:c.*789A>G","THREE_PRIME_EXON","Unknown significance",,,"rs573999764",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,1,694,0.0014,0,1008,0,0,978,0,2,5008,0.000399361,,,,,,,,,,,,,,,,,,,,,,,,
416098,"chr19:10333774:T>C","S1PR2",,"NM_004230:c.*746A>G","THREE_PRIME_EXON","Benign",,,"rs11880277",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,313,1322,0.2368,1,1006,0.001,6,694,0.0086,0,1008,0,1,978,0.001,321,5008,0.0640974,,,,,,,,,,,,,,,,,,,,,,,,
416099,"chr19:10333811:C>T","S1PR2",,"NM_004230:c.*709G>A","THREE_PRIME_EXON","Unknown significance",,,"rs11672059",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416100,"chr19:10333830:G>A","S1PR2",,"NM_004230:c.*690C>T","THREE_PRIME_EXON","Benign",,,"rs113804225",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,77,1322,0.0582,0,1006,0,4,694,0.0058,0,1008,0,0,978,0,81,5008,0.0161741,,,,,,,,,,,,,,,,,,,,,,,,
416101,"chr19:10333841:T>C","S1PR2",,"NM_004230:c.*679A>G","THREE_PRIME_EXON","Unknown significance",,,"rs761763926",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416102,"chr19:10333842:C>T","S1PR2",,"NM_004230:c.*678G>A","THREE_PRIME_EXON","Unknown significance",,,"rs148328365",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416103,"chr19:10333845:AAAAAAAAAAA>-","S1PR2",,"NM_004230:c.*675_*687delTTTTTTTTTTT","THREE_PRIME_EXON","Unknown significance",,,"rs779228186",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416104,"chr19:10333934:G>A","S1PR2",,"NM_004230:c.*586C>T","THREE_PRIME_EXON","Benign",,,"rs538799740",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,1,694,0.0014,0,1008,0,6,978,0.0061,8,5008,0.00159744,,,,,,,,,,,,,,,,,,,,,,,,
416105,"chr19:10333979:G>A","S1PR2",,"NM_004230:c.*541C>T","THREE_PRIME_EXON","Unknown significance",,,"rs189137467",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416106,"chr19:10333980:G>A","S1PR2",,"NM_004230:c.*540C>T","THREE_PRIME_EXON","Unknown significance",,,"rs558789721",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416107,"chr19:10334028:G>A","S1PR2",,"NM_004230:c.*492C>T","THREE_PRIME_EXON","Benign",,,"rs144320768",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,10,1322,0.0076,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,11,5008,0.00219649,,,,,,,,,,,,,,,,,,,,,,,,
416108,"chr19:10334030:C>T","S1PR2",,"NM_004230:c.*490G>A","THREE_PRIME_EXON","Unknown significance",,,"rs564208800",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,4,978,0.0041,4,5008,0.000798722,,,,,,,,,,,,,,,,,,,,,,,,
416109,"chr19:10334031:A>G","S1PR2",,"NM_004230:c.*489T>C","THREE_PRIME_EXON","Unknown significance",,,"rs528150291",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,4,978,0.0041,4,5008,0.000798722,,,,,,,,,,,,,,,,,,,,,,,,
416110,"chr19:10334039:A>G","S1PR2",,"NM_004230:c.*481T>C","THREE_PRIME_EXON","Unknown significance",,,"rs756289370",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416111,"chr19:10334076:G>A","S1PR2",,"NM_004230:c.*444C>T","THREE_PRIME_EXON","Unknown significance",,,"rs546621525",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2,1322,0.0015,1,1006,0.001,0,694,0,0,1008,0,0,978,0,3,5008,0.000599042,,,,,,,,,,,,,,,,,,,,,,,,
416112,"chr19:10334093:C>A","S1PR2",,"NM_004230:c.*427G>T","THREE_PRIME_EXON","Unknown significance",,,"rs181902354",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2,1322,0.0015,0,1006,0,0,694,0,0,1008,0,0,978,0,2,5008,0.000399361,,,,,,,,,,,,,,,,,,,,,,,,
416113,"chr19:10334102:C>T","S1PR2",,"NM_004230:c.*418G>A","THREE_PRIME_EXON","Benign",,,"rs183589749",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,5,1006,0.005,2,694,0.0029,0,1008,0,4,978,0.0041,11,5008,0.00219649,,,,,,,,,,,,,,,,,,,,,,,,
416114,"chr19:10334110:C>G","S1PR2",,"NM_004230:c.*410G>C","THREE_PRIME_EXON","Benign",,,"rs188338262",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,10,1322,0.0076,0,1006,0,0,694,0,0,1008,0,0,978,0,10,5008,0.00199681,,,,,,,,,,,,,,,,,,,,,,,,
416115,"chr19:10334115:T>C","S1PR2",,"NM_004230:c.*405A>G","THREE_PRIME_EXON","Unknown significance",,,"rs561184497",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416116,"chr19:10334118:C>T","S1PR2",,"NM_004230:c.*402G>A","THREE_PRIME_EXON","Unknown significance",,,"rs559827831",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416117,"chr19:10334119:G>T","S1PR2",,"NM_004230:c.*401C>A","THREE_PRIME_EXON","Unknown significance",,,"rs534824645",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416118,"chr19:10334120:C>T","S1PR2",,"NM_004230:c.*400G>A","THREE_PRIME_EXON","Benign",,,"rs181198866",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,6,1008,0.006,0,978,0,6,5008,0.00119808,,,,,,,,,,,,,,,,,,,,,,,,
416119,"chr19:10334130:->C","S1PR2",,"NM_004230:c.*390_*391insG","THREE_PRIME_EXON","Unknown significance",,,"rs34016247",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416120,"chr19:10334156:C>T","S1PR2",,"NM_004230:c.*364G>A","THREE_PRIME_EXON","Unknown significance",,,"rs539668453",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,1,978,0.001,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416121,"chr19:10334190:G>A","S1PR2",,"NM_004230:c.*330C>T","THREE_PRIME_EXON","Unknown significance",,,"rs754654557",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416122,"chr19:10334198:G>A","S1PR2",,"NM_004230:c.*322C>T","THREE_PRIME_EXON","Unknown significance",,,"rs767819389",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416123,"chr19:10334252:A>C","S1PR2",,"NM_004230:c.*268T>G","THREE_PRIME_EXON","Unknown significance",,,"rs557522753",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416124,"chr19:10334285:G>A","S1PR2",,"NM_004230:c.*235C>T","THREE_PRIME_EXON","Unknown significance",,,"rs566636069",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416125,"chr19:10334325:G>A","S1PR2",,"NM_004230:c.*195C>T","THREE_PRIME_EXON","Unknown significance",,,"rs533986129",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,1,978,0.001,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416126,"chr19:10334329:G>A","S1PR2",,"NM_004230:c.*191C>T","THREE_PRIME_EXON","Unknown significance",,,"rs555080829",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416127,"chr19:10334382:G>A","S1PR2",,"NM_004230:c.*138C>T","THREE_PRIME_EXON","Benign",,,"rs116309379",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,24,1322,0.0182,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,25,5008,0.00499201,,,,,,,,,,,,,,,,,,,,,,,,
416128,"chr19:10334417:C>T","S1PR2",,"NM_004230:c.*103G>A","THREE_PRIME_EXON","Unknown significance",,,"rs574009566",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416129,"chr19:10334418:G>A","S1PR2",,"NM_004230:c.*102C>T","THREE_PRIME_EXON","Unknown significance",,,"rs753016578",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416130,"chr19:10334440:C>T","S1PR2",,"NM_004230:c.*80G>A","THREE_PRIME_EXON","Benign",,,"rs537826575",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,16,1322,0.0121,0,1006,0,0,694,0,0,1008,0,0,978,0,16,5008,0.00319489,,,,,,,,,,,,,,,,,,,,,,,,
416131,"chr19:10334443:A>C","S1PR2",,"NM_004230:c.*77T>G","THREE_PRIME_EXON","Benign",,,"rs2116941",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1142,1322,0.8638,821,1006,0.8161,558,694,0.804,564,1008,0.5595,785,978,0.8027,3870,5008,0.772764,,,,,,,,,,,,,,,,,,,,,,,,
416132,"chr19:10334443:A>T","S1PR2",,"NM_004230:c.*77T>A","THREE_PRIME_EXON","Unknown significance",,,"rs2116941",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416133,"chr19:10334457:G>T","S1PR2",,"NM_004230:c.*63C>A","THREE_PRIME_EXON","Unknown significance",,,"rs578178978",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416134,"chr19:10334470:C>G","S1PR2",,"NM_004230:c.*50G>C","THREE_PRIME_EXON","Unknown significance",,,"rs761373331",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,8886,0,0,11298,0,0,8340,0,0,6450,0,1,60500,0.0000165289,0,736,0,0,8814,0,1,105024,0.00000952163
416135,"chr19:10334474:C>A","S1PR2",,"NM_004230:c.*46G>T","THREE_PRIME_EXON","Unknown significance",,,"rs764867123",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,8886,0,2,11294,0.000177085,0,8344,0,0,6442,0,0,60524,0,0,738,0,0,8814,0,2,105042,0.00001904
416136,"chr19:10334476:A>G","S1PR2",,"NM_004230:c.*44T>C","THREE_PRIME_EXON","Unknown significance",,,"rs772959230",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,8884,0,0,11304,0,1,8352,0.000119732,0,6454,0,0,60590,0,0,742,0,0,8842,0,1,105168,0.0000095086
416137,"chr19:10334478:G>T","S1PR2",,"NM_004230:c.*42C>A","THREE_PRIME_EXON","Unknown significance",,,"rs545591591",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,1,978,0.001,1,5008,0.000199681,0,8882,0,0,11294,0,0,8338,0,0,6462,0,0,60600,0,0,738,0,13,8846,0.00146959,13,105160,0.000123621
416138,"chr19:10334480:A>G","S1PR2",,"NM_004230:c.*40T>C","THREE_PRIME_EXON","Unknown significance",,,"rs767947690",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,8908,0,0,11302,0,0,8354,0,0,6458,0,1,60652,0.0000164875,0,742,0,0,8842,0,1,105258,0.00000950047
416139,"chr19:10334481:C>A","S1PR2",,"NM_004230:c.*39G>T","THREE_PRIME_EXON","Unknown significance",,,"rs753104727",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,8900,0.00011236,0,11306,0,0,8352,0,0,6464,0,0,60650,0,0,740,0,0,8848,0,1,105260,0.00000950029
416140,"chr19:10334483:C>T","S1PR2",,"NM_004230:c.*37G>A","THREE_PRIME_EXON","Unknown significance",,,"rs560621469",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416141,"chr19:10334494:G>T","S1PR2",,"NM_004230:c.*26C>A","THREE_PRIME_EXON","Unknown significance",,,"rs370864731",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,0,8574,0,2,4368,0.000457875,2,12942,0.000154536,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2,8958,0.000223264,0,11342,0,0,8376,0,0,6464,0,0,60852,0,0,746,0,0,8868,0,2,105606,0.0000189383
416142,"chr19:10334497:T>C","S1PR2",,"NM_004230:c.*23A>G","THREE_PRIME_EXON","Unknown significance",,,"rs764211203",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,8968,0,0,11356,0,1,8380,0.000119332,0,6482,0,0,60958,0,0,746,0,0,8888,0,1,105778,0.00000945376
416143,"chr19:10334499:GTT>-","S1PR2",,"NM_004230:c.*21_*25delAAC","THREE_PRIME_EXON","Unknown significance",,,"rs753076607",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2,8990,0.000222469,1,11354,0.0000880747,0,8384,0,0,6480,0,0,60996,0,0,746,0,0,8898,0,3,105848,0.0000283425
416144,"chr19:10334516:A>C","S1PR2",,"NM_004230:c.*4T>G","THREE_PRIME_EXON","Unknown significance",,,,,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9074,0,0,11382,0,0,8388,0,0,6506,0,3,61290,0.0000489476,0,742,0,0,8954,0,3,106336,0.0000282125
416145,"chr19:10334517:C>-","S1PR2",,"NM_004230:c.*3delG","THREE_PRIME_EXON","Unknown significance",,,"rs763419270",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9074,0,0,11382,0,0,8388,0,0,6506,0,2,61290,0.0000326318,0,742,0,0,8954,0,2,106336,0.0000188083
416146,"chr19:10334517:C>A","S1PR2",,"NM_004230:c.*3G>T","THREE_PRIME_EXON","Unknown significance",,,"rs372799945",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,1,8596,0.000116333,0,4400,0,1,12996,0.0000769468,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9078,0,0,11384,0,0,8390,0,0,6510,0,1,61302,0.0000163127,0,742,0,0,8962,0,1,106368,0.00000940132
416147,"chr19:10334524:A>G","S1PR2","NM_004230:p.Val353Ala","NM_004230:c.1058T>C","EXON2","Unknown significance",,,"rs757477621",,,,"This variant is a VUS because it does not have enough information.",,1.083,"C",,,"0.97","D",0.000601,"D",0.987394,"D",,"5.28","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9120,0,0,11388,0,0,8390,0,0,6516,0,0,61428,0,0,746,0,2,8980,0.000222717,2,106568,0.0000187674
416148,"chr19:10334529:C>T","S1PR2","NM_004230:p.Thr351Thr","NM_004230:c.1053G>A","EXON2","Unknown significance",,,"rs779243053",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9164,0,0,11388,0,0,8394,0,0,6518,0,0,61530,0,0,750,0,1,8986,0.000111284,1,106730,0.00000936944
416149,"chr19:10334530:G>C","S1PR2","NM_004230:p.Thr351Arg","NM_004230:c.1052C>G","EXON2","Unknown significance",,,"rs750703133",,,,"This variant is a VUS because it does not have enough information.",,0.949,"N",,,"0.997","D",0.008503,"N",0.999986,"D",,"5.49","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9172,0,0,11390,0,0,8398,0,0,6516,0,1,61562,0.0000162438,0,752,0,0,8996,0,1,106786,0.00000936452
416150,"chr19:10334532:G>A","S1PR2","NM_004230:p.Asn350Asn","NM_004230:c.1050C>T","EXON2","Benign",,,"rs116191851",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,5,8598,0.000581531,404,4402,0.0917765,409,13000,0.0314615,,,,,,,,,,,,,,,,,,,,,,131,1322,0.0991,1,1006,0.001,2,694,0.0029,0,1008,0,0,978,0,134,5008,0.0267572,902,9302,0.0969684,40,11390,0.00351185,1,8398,0.000119076,0,6516,0,9,61574,0.000146166,4,750,0.00533333,0,9002,0,956,106932,0.00894026
416151,"chr19:10334542:A>G","S1PR2","NM_004230:p.Leu347Pro","NM_004230:c.1040T>C","EXON2","Unknown significance",,,"rs779925683",,,,"This variant is a VUS because it does not have enough information.",,1.083,"C",,,"0.0","B",0.599526,"N",0.99986,"D",,"5.49","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9272,0,0,11398,0,0,8402,0,0,6502,0,1,61656,0.000016219,0,750,0,0,9056,0,1,107036,0.00000934265
416152,"chr19:10334546:A>G","S1PR2","NM_004230:p.Phe346Leu","NM_004230:c.1036T>C","EXON2","Likely benign",,,"rs746867139",,,,"Pathogenicity is based on prediction data only. 2 out of 5 predictions were pathogenic.",,1.083,"C",,,"0.0","B",0.830826,"N",1,"N",,"4.46","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9236,0,0,11388,0,1,8398,0.000119076,0,6488,0,0,61606,0,0,750,0,0,9080,0,1,106946,0.00000935051
416153,"chr19:10334548:G>T","S1PR2","NM_004230:p.Thr345Lys","NM_004230:c.1034C>A","EXON2","Likely benign",,,"rs540296894",,,,"Pathogenicity is based on prediction data only. 1 out of 5 predictions were pathogenic.",,0.064,"N",,,"0.435","B",0.00374,"N",0.998881,"N",,"4.45","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,2,9254,0.000216123,0,11390,0,0,8402,0,0,6488,0,0,61644,0,0,750,0,0,9116,0,2,107044,0.0000186839
416154,"chr19:10334550:G>A","S1PR2","NM_004230:p.Pro344Pro","NM_004230:c.1032C>T","EXON2","Unknown significance",,,"rs561751764",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,0,9264,0,0,11392,0,1,8408,0.000118934,0,6490,0,0,61688,0,0,752,0,0,9144,0,1,107138,0.00000933376
416155,"chr19:10334551:G>T","S1PR2","NM_004230:p.Pro344His","NM_004230:c.1031C>A","EXON2","Unknown significance",,,"rs747628779",,,,"This variant is a VUS because it does not have enough information.",,0.949,"N",,,"0.998","D",0.005072,"N",0.91811,"D",,"5.49","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9270,0,0,11392,0,0,8410,0,0,6490,0,1,61702,0.0000162069,0,752,0,0,9152,0,1,107168,0.00000933114
416156,"chr19:10334556:C>T","S1PR2","NM_004230:p.Thr342Thr","NM_004230:c.1026G>A","EXON2","Unknown significance",,,"rs377376944",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,1,8598,0.000116306,0,4404,0,1,13002,0.0000769112,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9278,0,0,11390,0,4,8420,0.000475059,0,6486,0,5,61724,0.0000810058,0,750,0,1,9214,0.00010853,10,107262,0.0000932297
416157,"chr19:10334556:C>A","S1PR2","NM_004230:p.Thr342Thr","NM_004230:c.1026G>T","EXON2","Unknown significance",,,"rs377376944",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9278,0,0,11390,0,0,8420,0,0,6486,0,1,61724,0.0000162012,0,750,0,0,9214,0,1,107262,0.00000932297
416158,"chr19:10334557:G>A","S1PR2","NM_004230:p.Thr342Met","NM_004230:c.1025C>T","EXON2","Unknown significance",,,"rs762697846",,,,"This variant is a VUS because it does not have enough information.",,0.949,"N",,,"0.999","D",0.00489,"N",0.999926,"D",,"5.49","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9286,0,0,11388,0,0,8416,0,0,6478,0,1,61738,0.0000161975,0,750,0,0,9266,0,1,107322,0.00000931775
416159,"chr19:10334568:C>T","S1PR2","NM_004230:p.Met338Ile","NM_004230:c.1014G>A","EXON2","Likely benign",,,"rs772259151",,,,"Pathogenicity is based on prediction data only. 0 out of 5 predictions were pathogenic.",,-0.45,"N",,,"0.0","B",0.447133,"N",0.985703,"N",,"-2.93","N",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9272,0,0,11382,0,0,8438,0,0,6456,0,0,61772,0,0,752,0,1,9628,0.000103864,1,107700,0.00000928505
416160,"chr19:10334569:A>G","S1PR2","NM_004230:p.Met338Thr","NM_004230:c.1013T>C","EXON2","Likely benign",,,"rs775936073",,,,"Pathogenicity is based on prediction data only. 0 out of 5 predictions were pathogenic.",,-0.844,"N",,,"0.0","B",0.447133,"N",0.969363,"N",,"-1.89","N",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9286,0,14,11386,0.00122958,0,8438,0,0,6458,0,0,61792,0,0,754,0,0,9734,0,14,107848,0.000129812
416161,"chr19:10334573:C>A","S1PR2","NM_004230:p.Gly337Cys","NM_004230:c.1009G>T","EXON2","Likely benign",,,"rs761178651",,,,"Pathogenicity is based on prediction data only. 2 out of 5 predictions were pathogenic.",,0.848,"N",,,"0.001","B",0.168508,"N",0.948859,"D",,"3.94","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9262,0,0,11386,0,0,8452,0,0,6442,0,5,61748,0.0000809743,0,758,0,0,9938,0,5,107986,0.0000463023
416162,"chr19:10334583:G>A","S1PR2","NM_004230:p.Ser333Ser","NM_004230:c.999C>T","EXON2","Unknown significance",,,"rs764691626",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,9214,0.00010853,0,11374,0,0,8458,0,0,6396,0,0,61690,0,0,770,0,0,10666,0,1,108568,0.00000921082
416163,"chr19:10334590:G>C","S1PR2","NM_004230:p.Ser331Cys","NM_004230:c.992C>G","EXON2","Unknown significance",,,"rs754434903",,,,"This variant is a VUS because it does not have enough information.",,0.949,"N",,,"1.0","D",0.06082,"N",1,"D",,"5.49","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9182,0,1,11358,0.0000880437,0,8464,0,0,6374,0,0,61662,0,0,768,0,0,11100,0,1,108908,0.00000918206
416164,"chr19:10334596:C>T","S1PR2","NM_004230:p.Arg329His","NM_004230:c.986G>A","EXON2","Unknown significance",,,"rs143246348",,,,"This variant is a VUS because it does not have enough information.",,0.848,"N",,,"0.999","D",0.574503,"N",0.999137,"D",,"5.49","C",1,8598,0.000116306,0,4404,0,1,13002,0.0000769112,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9170,0,0,11330,0,0,8452,0,0,6330,0,3,61548,0.0000487424,0,770,0,0,11478,0,3,109078,0.0000275033
416165,"chr19:10334597:G>A","S1PR2","NM_004230:p.Arg329Cys","NM_004230:c.985C>T","EXON2","Unknown significance",,,"rs765378016",,,,"This variant is a VUS because it does not have enough information.",,0.949,"N",,,"1.0","D",0.574503,"N",0.999995,"D",,"4.42","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9108,0,0,11312,0,0,8454,0,0,6320,0,3,61276,0.0000489588,0,762,0,0,11566,0,3,108798,0.000027574
416166,"chr19:10334601:T>C","S1PR2","NM_004230:p.Pro327Pro","NM_004230:c.981A>G","EXON2","Unknown significance",,,"rs146709827",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,2,8598,0.000232612,0,4404,0,2,13002,0.000153822,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9002,0,0,11280,0,7,8432,0.000830171,0,6276,0,10,60912,0.000164171,0,766,0,0,11692,0,17,108360,0.000156884
416167,"chr19:10334608:A>G","S1PR2","NM_004230:p.Leu325Pro","NM_004230:c.974T>C","EXON2","Unknown significance",,,"rs758647424",,,,"This variant is a VUS because it does not have enough information.",,1.083,"C",,,"0.996","D",0.172188,"N",1,"D",,"5.49","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416168,"chr19:10334609:G>A","S1PR2","NM_004230:p.Leu325Phe","NM_004230:c.973C>T","EXON2","Likely benign",,,"rs780202015",,,,"Pathogenicity is based on prediction data only. 2 out of 5 predictions were pathogenic.",,0.949,"N",,,"0.076","B",0.172188,"N",0.915763,"D",,"4.46","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,8976,0,0,11248,0,0,8418,0,1,6224,0.000160668,0,60820,0,0,760,0,0,12314,0,1,108760,0.00000919456
416169,"chr19:10334610:G>C","S1PR2","NM_004230:p.His324Gln","NM_004230:c.972C>G","EXON2","Likely benign",,,"rs370704501",,,,"Pathogenicity is based on prediction data only. 0 out of 5 predictions were pathogenic.",,-0.426,"N",,,"0.0","B",0.869167,"N",0.999069,"N",,"-0.0682","N",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416170,"chr19:10334610:G>A","S1PR2","NM_004230:p.His324His","NM_004230:c.972C>T","EXON2","Unknown significance",,,"rs370704501",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,1,8596,0.000116333,0,4402,0,1,12998,0.0000769349,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,8892,0,0,11216,0,0,8408,0,0,6186,0,1,60586,0.0000165055,0,764,0,0,12308,0,1,108360,0.0000092285
416171,"chr19:10334611:T>G","S1PR2","NM_004230:p.His324Pro","NM_004230:c.971A>C","EXON2","Likely benign",,,"rs754811711",,,,"Pathogenicity is based on prediction data only. 0 out of 5 predictions were pathogenic.",,-1.733,"N",,,"0.105","B",0.869167,"N",0.996076,"N",,"-3.79","N",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416172,"chr19:10334614:T>G","S1PR2","NM_004230:p.His323Pro","NM_004230:c.968A>C","EXON2","Unknown significance",,,"rs781086264",,,,"This variant is a VUS because it does not have enough information.",,0.961,"C",,,"0.475","P",0.111793,"N",0.991349,"D",,"3.01","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416173,"chr19:10334619:C>T","S1PR2","NM_004230:p.Pro321Pro","NM_004230:c.963G>A","EXON2","Unknown significance",,,"rs748108934",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,8664,0,2,11130,0.000179695,0,8298,0,0,6016,0,1,59630,0.0000167701,0,750,0,0,13060,0,3,107548,0.0000278945
416174,"chr19:10334621:G>C","S1PR2","NM_004230:p.Pro321Ala","NM_004230:c.961C>G","EXON2","Likely benign",,,"rs769255115",,,,"Pathogenicity is based on prediction data only. 2 out of 5 predictions were pathogenic.",,0.949,"N",,,"0.132","B",0.62882,"N",0.999789,"D",,"5.49","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,8708,0,0,11152,0,0,8336,0,0,6036,0,0,59922,0,0,760,0,2,13172,0.000151837,2,108086,0.0000185038
416175,"chr19:10334624:T>C","S1PR2","NM_004230:p.Thr320Ala","NM_004230:c.958A>G","EXON2","Likely benign",,,"rs777343288",,,,"Pathogenicity is based on prediction data only. 2 out of 5 predictions were pathogenic.",,0.961,"C",,,"0.001","B",0.850092,"N",0.907028,"N",,"3.42","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,8316,0,0,10860,0,0,8028,0,0,5380,0,1,57784,0.0000173058,0,706,0,0,12402,0,1,103476,0.00000966408
416176,"chr19:10334625:C>T","S1PR2","NM_004230:p.Gly319Gly","NM_004230:c.957G>A","EXON2","Unknown significance",,,"rs748833361",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416177,"chr19:10334627:C>T","S1PR2","NM_004230:p.Gly319Arg","NM_004230:c.955G>A","EXON2","Likely benign",,,"rs139097585",,,,"Pathogenicity is based on prediction data only. 1 out of 5 predictions were pathogenic.",,0.848,"N",,,"0.001","B",0.654838,"N",0.922875,"N",,"0.917","C",2,8580,0.0002331,1,4390,0.00022779,3,12970,0.000231303,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,8530,0.000117233,0,11088,0,0,8270,0,0,5906,0,8,59338,0.000134821,0,744,0,0,13416,0,9,107292,0.0000838832
416178,"chr19:10334628:G>A","S1PR2","NM_004230:p.Gly318Gly","NM_004230:c.954C>T","EXON2","Unknown significance",,,"rs773940288",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,8496,0,0,11062,0,0,8250,0,0,5836,0,1,59182,0.000016897,0,744,0,0,13368,0,1,106938,0.00000935121
416179,"chr19:10334632:C>T","S1PR2","NM_004230:p.Arg317Gln","NM_004230:c.950G>A","EXON2","Unknown significance",,,"rs201451279",,,,"This variant is a VUS because it does not have enough information.",,0.012,"N",,,"0.8","P",0.870226,"N",0.522058,"D",,"4.46","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,0,8462,0,0,11068,0,0,8272,0,0,5902,0,2,59294,0.0000337302,0,752,0,0,13576,0,2,107326,0.0000186348
416180,"chr19:10334633:G>A","S1PR2","NM_004230:p.Arg317Trp","NM_004230:c.949C>T","EXON2","Unknown significance",,,"rs376162016",,,,"This variant is a VUS because it does not have enough information.",,0.78,"N",,,"1.0","D",0.870226,"N",0.936728,"D",,"4.43","C",1,8562,0.000116795,0,4378,0,1,12940,0.0000772798,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,1,978,0.001,1,5008,0.000199681,0,8454,0,0,11054,0,0,8268,0,0,5806,0,5,59292,0.0000843284,0,746,0,1,13604,0.0000735078,6,107224,0.0000559576
416181,"chr19:10334638:C>T","S1PR2","NM_004230:p.Arg315Gln","NM_004230:c.944G>A","EXON2","Likely benign",,,"rs777226501",,,,"Pathogenicity is based on prediction data only. 2 out of 5 predictions were pathogenic.",,0.848,"N",,,"0.829","P",0.420256,"N",0.982797,"N",,"4.42","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,8430,0,4,11096,0.00036049,0,8246,0,0,5908,0,3,59484,0.0000504337,0,758,0,0,13974,0,7,107896,0.0000648773
416182,"chr19:10334639:G>A","S1PR2","NM_004230:p.Arg315Trp","NM_004230:c.943C>T","EXON2","Likely benign",,,"rs762437563",,,,"Pathogenicity is based on prediction data only. 2 out of 5 predictions were pathogenic.",,0.949,"N",,,"0.994","D",0.420256,"N",0.999819,"N",,"1.79","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,8438,0,0,11078,0,10,8252,0.00121183,0,5866,0,0,59530,0,0,768,0,0,14030,0,10,107962,0.0000926252
416183,"chr19:10334647:A>C","S1PR2","NM_004230:p.Val312Gly","NM_004230:c.935T>G","EXON2","Likely benign",,,"rs765160621",,,,"Pathogenicity is based on prediction data only. 1 out of 5 predictions were pathogenic.",,1.083,"C",,,"0.0","B",0.401901,"N",0.999987,"N",,"-3.36","N",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416184,"chr19:10334648:C>G","S1PR2","NM_004230:p.Val312Leu","NM_004230:c.934G>C","EXON2","Likely benign",,,"rs750507202",,,,"Pathogenicity is based on prediction data only. 0 out of 5 predictions were pathogenic.",,0.848,"N",,,"0.0","B",0.401901,"N",1,"N",,"-1.37","N",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,8216,0,2,11072,0.000180636,0,8218,0,0,5960,0,0,59200,0,0,772,0,0,14458,0,2,107896,0.0000185364
416185,"chr19:10334653:A>C","S1PR2","NM_004230:p.Val310Gly","NM_004230:c.929T>G","EXON2","Likely benign",,,"rs763014040",,,,"Pathogenicity is based on prediction data only. 0 out of 5 predictions were pathogenic.",,-0.471,"N",,,"0.001","B",0.6913,"N",1,"N",,"-1.01","N",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416186,"chr19:10334655:C>A","S1PR2","NM_004230:p.Gly309Gly","NM_004230:c.927G>T","EXON2","Unknown significance",,,"rs766595919",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,8228,0,0,11078,0,0,8200,0,0,5990,0,1,59374,0.0000168424,0,776,0,0,14752,0,1,108398,0.00000922526
416187,"chr19:10334656:C>A","S1PR2","NM_004230:p.Gly309Val","NM_004230:c.926G>T","EXON2","Likely benign",,,"rs751831715",,,,"Pathogenicity is based on prediction data only. 0 out of 5 predictions were pathogenic.",,-0.512,"N",,,"0.025","B",0.000172,"N",0.999975,"N",,"-0.332","N",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416188,"chr19:10334658:C>T","S1PR2","NM_004230:p.Pro308Pro","NM_004230:c.924G>A","EXON2","Unknown significance",,,"rs754720067",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,8220,0,0,11082,0,0,8202,0,0,5980,0,0,59454,0,0,778,0,2,14862,0.000134571,2,108578,0.0000184199
416189,"chr19:10334659:G>A","S1PR2","NM_004230:p.Pro308Leu","NM_004230:c.923C>T","EXON2","Unknown significance",,,"rs200973983",,,,"This variant is a VUS because it does not have enough information.",,-1.136,"N",,,"0.056","B",0.347955,"U",1,"N",,"-10.4","N",2,8496,0.000235405,1,4326,0.00023116,3,12822,0.000233973,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,5,8272,0.000604449,1,11064,0.0000903832,0,8214,0,0,5888,0,14,59448,0.0002355,0,780,0,0,14936,0,20,108602,0.000184159
416190,"chr19:10334662:C>T","S1PR2","NM_004230:p.Arg307Lys","NM_004230:c.920G>A","EXON2","Likely benign",,,"rs752564111",,,,"Pathogenicity is based on prediction data only. 1 out of 5 predictions were pathogenic.",,-0.491,"N",,,"0.0","B",0.719289,"N",1,"N",,"0.584","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,8370,0.000119474,0,11122,0,0,8236,0,0,6010,0,0,59998,0,0,788,0,0,15146,0,1,109670,0.00000911826
416191,"chr19:10334663:T>A","S1PR2","NM_004230:p.Arg307Trp","NM_004230:c.919A>T","EXON2","Likely benign",,,"rs2116942",,,,"Pathogenicity is based on prediction data only. 1 out of 5 predictions were pathogenic.",,-0.413,"N",,,"0.0","B",0.719289,"N",0.997003,"N",,"1.65","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,8830,0,0,11030,0,27,8210,0.00328867,2,5908,0.000338524,0,61294,0,0,812,0,1,16034,0.0000623675,30,112118,0.000267575
416192,"chr19:10334663:T>G","S1PR2","NM_004230:p.Arg307Arg","NM_004230:c.919A>C","EXON2","Benign",,,"rs2116942",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,5012,8518,0.588401,3127,4346,0.719512,8139,12864,0.632696,,,,,,,,,,,,,,,,,,,,,,1015,1322,0.7678,593,1006,0.5895,317,694,0.4568,312,1008,0.3095,527,978,0.5389,2764,5008,0.551917,6474,8830,0.733182,4622,11030,0.419039,2485,8210,0.30268,2957,5908,0.500508,35951,61294,0.586534,469,812,0.577586,8366,16034,0.521766,61324,112118,0.546959
416193,"chr19:10334667:G>C","S1PR2","NM_004230:p.Cys305Trp","NM_004230:c.915C>G","EXON2","Unknown significance",,,"rs748826184",,,,"This variant is a VUS because it does not have enough information.",,0.949,"N",,,"0.97","D",0,"D",1,"D",,"4.45","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,8970,0,0,11208,0,1,8270,0.000120919,0,6110,0,0,62054,0,0,824,0,0,16114,0,1,113550,0.00000880669
416194,"chr19:10334673:C>T","S1PR2","NM_004230:p.Leu303Leu","NM_004230:c.909G>A","EXON2","Unknown significance",,,"rs756755776",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,8982,0,1,11218,0.0000891424,0,8278,0,0,6134,0,0,62096,0,0,824,0,0,16150,0,1,113682,0.00000879647
416195,"chr19:10334676:C>T","S1PR2","NM_004230:p.Pro302Pro","NM_004230:c.906G>A","EXON2","Unknown significance",,,"rs778604580",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9006,0,1,11218,0.0000891424,1,8280,0.000120773,0,6128,0,0,62094,0,0,824,0,7,16160,0.000433168,9,113710,0.0000791487
416196,"chr19:10334677:G>A","S1PR2","NM_004230:p.Pro302Leu","NM_004230:c.905C>T","EXON2","Unknown significance",,,"rs528470769",,,,"This variant is a VUS because it does not have enough information.",,0.953,"C",,,"0.001","B",0.013339,"N",0.999959,"D",,"3.38","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9058,0,0,11222,0,0,8274,0,0,6142,0,2,62224,0.0000321419,0,830,0,0,16188,0,2,113938,0.0000175534
416197,"chr19:10334679:C>T","S1PR2","NM_004230:p.Arg301Arg","NM_004230:c.903G>A","EXON2","Benign",,,"rs149865919",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,0,8578,0,69,4386,0.0157319,69,12964,0.00532243,,,,,,,,,,,,,,,,,,,,,,43,1322,0.0325,0,1006,0,0,694,0,0,1008,0,0,978,0,43,5008,0.00858626,145,9094,0.0159446,10,11236,0.000889996,0,8280,0,0,6158,0,3,62298,0.0000481556,0,832,0,1,16200,0.0000617284,159,114098,0.00139354
416198,"chr19:10334679:C>A","S1PR2","NM_004230:p.Arg301Arg","NM_004230:c.903G>T","EXON2","Unknown significance",,,"rs149865919",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9094,0,0,11236,0,0,8280,0,0,6158,0,0,62298,0,0,832,0,1,16200,0.0000617284,1,114098,0.0000087644
416199,"chr19:10334680:C>G","S1PR2","NM_004230:p.Arg301Pro","NM_004230:c.902G>C","EXON2","Unknown significance",,,"rs748604714",,,,"This variant is a VUS because it does not have enough information.",,0.852,"N",,,"1.0","D",0.000001,"D",1,"D",,"5.49","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9110,0,0,11240,0,0,8278,0,0,6148,0,1,62316,0.0000160472,0,828,0,0,16208,0,1,114128,0.00000876209
416200,"chr19:10334681:G>A","S1PR2","NM_004230:p.Arg301Trp","NM_004230:c.901C>T","EXON2","Unknown significance",,,"rs551166280",,,,"This variant is a VUS because it does not have enough information.",,0.075,"N",,,"1.0","D",0.000001,"D",0.999997,"D",,"3.28","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,2,978,0.002,2,5008,0.000399361,0,9194,0,0,11234,0,0,8276,0,0,6156,0,0,62454,0,0,832,0,22,16238,0.00135485,22,114384,0.000192335
416201,"chr19:10334686:A>C","S1PR2","NM_004230:p.Val299Gly","NM_004230:c.896T>G","EXON2","Unknown significance",,,"rs79193144",,,,"This variant is a VUS because it does not have enough information.",,1.088,"C",,,"0.971","D",0.000053,"D",1,"D",,"5.49","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416202,"chr19:10334692:C>G","S1PR2","NM_004230:p.Arg297Pro","NM_004230:c.890G>C","EXON2","Unknown significance",,,"rs773635875",,,,"This variant is a VUS because it does not have enough information.",,0.852,"N",,,"0.8","P",0.012065,"N",0.929115,"D",,"2.2","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9310,0,0,11270,0,0,8298,0,0,6234,0,0,62908,0,0,836,0,1,16334,0.000061222,1,115190,0.00000868131
416203,"chr19:10334693:G>A","S1PR2","NM_004230:p.Arg297Trp","NM_004230:c.889C>T","EXON2","Likely benign",,,"rs763068319",,,,"Pathogenicity is based on prediction data only. 2 out of 5 predictions were pathogenic.",,0.017,"N",,,"0.99","D",0.012065,"N",0.923613,"D",,"-1.58","N",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9342,0,1,11280,0.0000886525,0,8302,0,0,6226,0,0,63018,0,0,838,0,0,16348,0,1,115354,0.00000866897
416204,"chr19:10334695:C>T","S1PR2","NM_004230:p.Arg296Gln","NM_004230:c.887G>A","EXON2","Unknown significance",,,"rs766392869",,,,"This variant is a VUS because it does not have enough information.",,0.852,"N",,,"1.0","D",0,"D",1,"D",,"5.49","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9312,0,0,11282,0,0,8302,0,0,6230,0,1,62988,0.000015876,0,836,0,1,16356,0.0000611396,2,115306,0.0000173452
416205,"chr19:10334696:G>A","S1PR2","NM_004230:p.Arg296Trp","NM_004230:c.886C>T","EXON2","Unknown significance",,,"rs774518653",,,,"This variant is a VUS because it does not have enough information.",,0.953,"C",,,"1.0","D",0,"D",0.999994,"D",,"2.03","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9234,0,0,11282,0,0,8302,0,0,6244,0,1,62898,0.0000158988,0,838,0,0,16366,0,1,115164,0.00000868327
416206,"chr19:10334700:G>A","S1PR2","NM_004230:p.Asp294Asp","NM_004230:c.882C>T","EXON2","Unknown significance",,,"rs35493500",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,0,9328,0,1,11290,0.000088574,40,8306,0.0048158,0,6250,0,12,63160,0.000189994,0,840,0,0,16384,0,53,115558,0.000458644
416207,"chr19:10334703:C>G","S1PR2","NM_004230:p.Arg293Arg","NM_004230:c.879G>C","EXON2","Unknown significance",,,"rs767243037",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9354,0,0,11294,0,0,8302,0,0,6244,0,1,63236,0.0000158138,0,842,0,0,16396,0,1,115668,0.00000864543
416208,"chr19:10334704:C>T","S1PR2","NM_004230:p.Arg293Gln","NM_004230:c.878G>A","EXON2","Likely benign",,,"rs376403797",,,,"Pathogenicity is based on prediction data only. 2 out of 5 predictions were pathogenic.",,0.852,"N",,,"0.09","B",0.000594,"N",0.919956,"D",,"4.46","C",1,8598,0.000116306,0,4402,0,1,13000,0.0000769231,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9374,0,0,11296,0,0,8306,0,0,6240,0,1,63264,0.0000158068,0,842,0,0,16388,0,1,115710,0.0000086423
416209,"chr19:10334705:G>A","S1PR2","NM_004230:p.Arg293Trp","NM_004230:c.877C>T","EXON2","Unknown significance",,,"rs370698200",,,,"This variant is a VUS because it does not have enough information.",,0.953,"C",,,"0.996","D",0.000594,"D",0.994642,"D",,"4.38","C",2,8600,0.000232558,0,4404,0,2,13004,0.000153799,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9474,0,0,11290,0,0,8312,0,0,6244,0,2,63418,0.0000315368,0,846,0,0,16398,0,2,115982,0.0000172441
416210,"chr19:10334715:C>T","S1PR2","NM_004230:p.Thr289Thr","NM_004230:c.867G>A","EXON2","Unknown significance",,,"rs557191214",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9642,0,0,11334,0,0,8324,0,0,6274,0,6,63952,0.0000938204,0,850,0,0,16428,0,6,116804,0.0000513681
416211,"chr19:10334716:G>A","S1PR2","NM_004230:p.Thr289Met","NM_004230:c.866C>T","EXON2","Unknown significance",,,"rs373228288",,,,"This variant is a VUS because it does not have enough information.",,0.953,"C",,,"1.0","D",0,"D",1,"D",,"5.49","C",1,8600,0.000116279,0,4406,0,1,13006,0.0000768876,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9678,0,0,11332,0,0,8326,0,0,6276,0,3,64024,0.0000468574,0,852,0,0,16434,0,3,116922,0.0000256581
416212,"chr19:10334722:A>G","S1PR2","NM_004230:p.Ile287Thr","NM_004230:c.860T>C","EXON2","Unknown significance",,,"rs144903812",,,,"This variant is a VUS because it does not have enough information.",,1.088,"C",,,"1.0","D",0,"D",1,"D",,"5.49","C",1,8600,0.000116279,0,4404,0,1,13004,0.0000768994,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9754,0,0,11346,0,0,8330,0,0,6286,0,1,64224,0.0000155705,0,854,0,0,16440,0,1,117234,0.00000852995
416213,"chr19:10334725:A>G","S1PR2","NM_004230:p.Val286Ala","NM_004230:c.857T>C","EXON2","Benign",,,"rs117064827",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,1.088,"C",,,"0.961","D",0.003723,"N",0.999794,"D",,"5.49","C",77,8600,0.00895349,8,4404,0.00181653,85,13004,0.00653645,,,,,,,,,,,,,,,,,,,,,,0,1322,0,14,1006,0.0139,1,694,0.0014,2,1008,0.002,0,978,0,17,5008,0.00339457,16,9784,0.00163532,29,11350,0.00255507,21,8332,0.0025204,63,6294,0.0100095,663,64316,0.0103085,3,858,0.0034965,47,16440,0.00285888,842,117374,0.00717365
416214,"chr19:10334726:C>T","S1PR2","NM_004230:p.Val286Ile","NM_004230:c.856G>A","EXON2","Unknown significance",,,"rs377336539",,,,"This variant is a VUS because it does not have enough information.",,0.852,"N",,,"0.65","P",0.003723,"N",0.919813,"D",,"4.46","C",2,8600,0.000232558,0,4404,0,2,13004,0.000153799,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9792,0,0,11348,0,0,8332,0,0,6284,0,6,64338,0.0000932575,0,858,0,0,16434,0,6,117386,0.0000511134
416215,"chr19:10334727:G>A","S1PR2","NM_004230:p.Pro285Pro","NM_004230:c.855C>T","EXON2","Unknown significance",,,"rs202092003",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,0,9826,0,0,11354,0,22,8334,0.00263979,0,6298,0,2,64412,0.0000310501,0,856,0,0,16438,0,24,117518,0.000204224
416216,"chr19:10334738:G>A","S1PR2","NM_004230:p.Leu282Leu","NM_004230:c.844C>T","EXON2","Unknown significance",,,"rs186708543",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,0,9896,0,0,11368,0,17,8360,0.00203349,0,6320,0,1,64648,0.0000154684,0,866,0,0,16450,0,18,117908,0.000152661
416217,"chr19:10334748:G>T","S1PR2","NM_004230:p.Thr278Thr","NM_004230:c.834C>A","EXON2","Unknown significance",,,"rs201888564",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416218,"chr19:10334753:A>G","S1PR2","NM_004230:p.Ser277Pro","NM_004230:c.829T>C","EXON2","Unknown significance",,,"rs748496507",,,,"This variant is a VUS because it does not have enough information.",,0.018,"N",,,"0.001","B",0,"D",0.846349,"D",,"4.46","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9944,0,0,11392,0,0,8382,0,0,6336,0,1,64888,0.0000154112,0,868,0,0,16452,0,1,118262,0.0000084558
416219,"chr19:10334756:C>T","S1PR2","NM_004230:p.Val276Ile","NM_004230:c.826G>A","EXON2","Likely benign",,,"rs146537931",,,,"Pathogenicity is based on prediction data only. 2 out of 5 predictions were pathogenic.",,0.165,"N",,,"0.029","B",0.000007,"D",0.998607,"N",,"5.49","C",0,8600,0,7,4406,0.00158874,7,13006,0.000538213,,,,,,,,,,,,,,,,,,,,,,2,1322,0.0015,0,1006,0,0,694,0,0,1008,0,1,978,0.001,3,5008,0.000599042,13,9952,0.00130627,0,11390,0,0,8386,0,0,6328,0,2,64908,0.0000308128,0,866,0,7,16452,0.00042548,22,118282,0.000185996
416220,"chr19:10334757:G>A","S1PR2","NM_004230:p.Ala275Ala","NM_004230:c.825C>T","EXON2","Unknown significance",,,"rs201255057",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,2,694,0.0029,1,1008,0.001,0,978,0,4,5008,0.000798722,0,9960,0,1,11394,0.0000877655,1,8396,0.000119104,0,6336,0,0,64912,0,0,866,0,1,16448,0.0000607977,3,118312,0.0000253567
416221,"chr19:10334759:C>T","S1PR2","NM_004230:p.Ala275Thr","NM_004230:c.823G>A","EXON2","Unknown significance",,,"rs371414653",,,,"This variant is a VUS because it does not have enough information.",,0.852,"N",,,"0.859","P",0.001267,"N",0.849147,"D",,"3.27","C",1,8600,0.000116279,0,4406,0,1,13006,0.0000768876,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9964,0,0,11396,0,0,8388,0,0,6334,0,1,64936,0.0000153998,0,866,0,1,16450,0.0000607903,2,118334,0.0000169013
416222,"chr19:10334760:G>A","S1PR2","NM_004230:p.Phe274Phe","NM_004230:c.822C>T","EXON2","Unknown significance",,,"rs200327403",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,0,9968,0,0,11400,0,2,8392,0.000238322,0,6344,0,0,64958,0,0,864,0,0,16452,0,2,118378,0.000016895
416223,"chr19:10334766:G>C","S1PR2","NM_004230:p.Tyr272Stop","NM_004230:c.816C>G","EXON2","Unknown significance",,,"rs774428989",,,,"This variant is a VUS because it does not have enough information.",,0.091,"N",,,,,0.002962,"N",1,"D",,"4.22","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9984,0,0,11412,0,0,8404,0,0,6348,0,1,65036,0.0000153761,0,868,0,0,16452,0,1,118504,0.00000843853
416224,"chr19:10334771:G>A","S1PR2","NM_004230:p.His271Tyr","NM_004230:c.811C>T","EXON2","Unknown significance",,,"rs375937928",,,,"This variant is a VUS because it does not have enough information.",,0.953,"C",,,"0.202","B",0.016727,"N",0.8723,"D",,"5.49","C",1,8600,0.000116279,0,4406,0,1,13006,0.0000768876,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9996,0,0,11412,0,0,8412,0,0,6366,0,1,65082,0.0000153652,0,872,0,0,16452,0,1,118592,0.00000843227
416225,"chr19:10334784:G>A","S1PR2","NM_004230:p.Ile266Ile","NM_004230:c.798C>T","EXON2","Unknown significance",,,"rs539310677",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,0,10018,0,0,11420,0,0,8430,0,0,6376,0,1,65142,0.0000153511,0,874,0,1,16454,0.0000607755,2,118714,0.0000168472
416226,"chr19:10334786:T>A","S1PR2","NM_004230:p.Ile266Phe","NM_004230:c.796A>T","EXON2","Likely benign",,,"rs147817898",,,,"Pathogenicity is based on prediction data only. 1 out of 5 predictions were pathogenic.",,-0.51,"N",,,"0.627","P",0.046133,"N",0.991306,"N",,"-8.51","N",1,8600,0.000116279,0,4406,0,1,13006,0.0000768876,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416227,"chr19:10334787:C>T","S1PR2","NM_004230:p.Pro265Pro","NM_004230:c.795G>A","EXON2","Unknown significance",,,"rs554422074",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,1,978,0.001,1,5008,0.000199681,0,10018,0,0,11416,0,0,8436,0,0,6374,0,3,65110,0.0000460759,0,874,0,1,16454,0.0000607755,4,118682,0.0000337035
416228,"chr19:10334788:G>C","S1PR2","NM_004230:p.Pro265Arg","NM_004230:c.794C>G","EXON2","Unknown significance",,,"rs572711891",,,,"This variant is a VUS because it does not have enough information.",,0.953,"C",,,"0.981","D",0.001327,"N",0.999441,"D",,"5.63","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,1,978,0.001,1,5008,0.000199681,0,10022,0,0,11424,0,0,8436,0,0,6370,0,0,65136,0,0,876,0,18,16454,0.00109396,18,118718,0.00015162
416229,"chr19:10334788:G>A","S1PR2","NM_004230:p.Pro265Leu","NM_004230:c.794C>T","EXON2","Unknown significance",,,"rs572711891",,,,"This variant is a VUS because it does not have enough information.",,0.953,"C",,,"0.985","D",0.001327,"N",0.999998,"D",,"5.63","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10022,0,0,11424,0,0,8436,0,0,6370,0,1,65136,0.0000153525,0,876,0,1,16454,0.0000607755,2,118718,0.0000168466
416230,"chr19:10334797:T>A","S1PR2","NM_004230:p.His262Leu","NM_004230:c.785A>T","EXON2","Likely benign",,,"rs753765649",,,,"Pathogenicity is based on prediction data only. 1 out of 5 predictions were pathogenic.",,0,"N",,,"0.0","B",0.006628,"N",1,"N",,"2.18","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10036,0,0,11424,0,0,8436,0,0,6378,0,1,65170,0.0000153445,0,876,0,0,16458,0,1,118778,0.00000841907
416231,"chr19:10334799:G>A","S1PR2","NM_004230:p.Val261Val","NM_004230:c.783C>T","EXON2","Unknown significance",,,"rs761658384",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10040,0,0,11422,0,5,8448,0.000591856,0,6386,0,0,65210,0,0,880,0,0,16462,0,5,118848,0.0000420705
416232,"chr19:10334801:C>T","S1PR2","NM_004230:p.Val261Ile","NM_004230:c.781G>A","EXON2","Likely benign",,,"rs199824841",,,,"Pathogenicity is based on prediction data only. 1 out of 5 predictions were pathogenic.",,0.007,"N",,,"0.14","B",0.008662,"N",1,"N",,"3.39","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,1,5008,0.000199681,0,10038,0,1,11424,0.000087535,0,8446,0,0,6380,0,0,65198,0,0,878,0,1,16464,0.0000607386,2,118828,0.000016831
416233,"chr19:10334802:G>A","S1PR2","NM_004230:p.Pro260Pro","NM_004230:c.780C>T","EXON2","Unknown significance",,,"rs776554535",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10046,0,0,11426,0,4,8452,0.000473261,0,6390,0,4,65216,0.0000613346,0,878,0,1,16462,0.000060746,9,118870,0.000075713
416234,"chr19:10334815:T>C","S1PR2","NM_004230:p.Asp256Gly","NM_004230:c.767A>G","EXON2","Unknown significance",,,"rs758026150",,,,"This variant is a VUS because it does not have enough information.",,0.964,"C",,,"0.996","D",0,"D",1,"D",,"5.63","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10046,0,0,11430,0,0,8470,0,0,6394,0,1,65264,0.0000153224,0,876,0,0,16472,0,1,118952,0.00000840675
416235,"chr19:10334825:G>A","S1PR2","NM_004230:p.Leu253Phe","NM_004230:c.757C>T","EXON2","Unknown significance",,,"rs779835099",,,,"This variant is a VUS because it does not have enough information.",,1.048,"C",,,"1.0","D",0.000001,"D",1,"D",,"5.81","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10076,0,0,11438,0,0,8476,0,0,6396,0,1,65294,0.0000153153,0,880,0,0,16478,0,1,119038,0.00000840068
416236,"chr19:10334829:G>A","S1PR2","NM_004230:p.Ser251Ser","NM_004230:c.753C>T","EXON2","Unknown significance",,,"rs751196531",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10072,0,0,11434,0,0,8480,0,0,6382,0,1,65282,0.0000153182,0,880,0,0,16478,0,1,119008,0.0000084028
416237,"chr19:10334833:A>C","S1PR2","NM_004230:p.Phe250Cys","NM_004230:c.749T>G","EXON2","Unknown significance",,,"rs756465285",,,,"This variant is a VUS because it does not have enough information.",,1.199,"C",,,"1.0","D",0,"D",1,"D",,"5.81","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10078,0,0,11444,0,0,8492,0,0,6388,0,1,65306,0.0000153125,0,878,0,0,16490,0,1,119076,0.000008398
416238,"chr19:10334838:G>T","S1PR2","NM_004230:p.Pro248Pro","NM_004230:c.744C>A","EXON2","Unknown significance",,,"rs141379245",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,6,8600,0.000697674,0,4406,0,6,13006,0.000461326,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10094,0,0,11450,0,0,8506,0,2,6384,0.000313283,68,65336,0.00104077,0,878,0,1,16486,0.0000606575,71,119134,0.000595968
416239,"chr19:10334838:G>A","S1PR2","NM_004230:p.Pro248Pro","NM_004230:c.744C>T","EXON2","Unknown significance",,,"rs141379245",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,10094,0.0000990688,0,11450,0,0,8506,0,0,6384,0,0,65336,0,0,878,0,0,16486,0,1,119134,0.00000839391
416240,"chr19:10334840:G>A","S1PR2","NM_004230:p.Pro248Ser","NM_004230:c.742C>T","EXON2","Unknown significance",,,"rs771414562",,,,"This variant is a VUS because it does not have enough information.",,1.048,"C",,,"1.0","D",0,"D",1,"D",,"5.81","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10044,0,0,11448,0,0,8500,0,0,6318,0,3,65216,0.000046001,0,874,0,0,16488,0,3,118888,0.0000252338
416241,"chr19:10334843:G>C","S1PR2","NM_004230:p.Leu247Val","NM_004230:c.739C>G","EXON2","Unknown significance",,,"rs779462145",,,,"This variant is a VUS because it does not have enough information.",,1.048,"C",,,"0.996","D",0.000007,"D",0.999994,"D",,"4.78","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10106,0,0,11460,0,0,8516,0,0,6388,0,0,65438,0,0,880,0,2,16490,0.000121286,2,119278,0.0000167676
416242,"chr19:10334847:G>A","S1PR2","NM_004230:p.Cys245Cys","NM_004230:c.735C>T","EXON2","Unknown significance",,,"rs745916504",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10130,0,0,11466,0,0,8522,0,0,6396,0,0,65504,0,1,880,0.00113636,0,16488,0,1,119386,0.00000837619
416243,"chr19:10334852:C>A","S1PR2","NM_004230:p.Val244Phe","NM_004230:c.730G>T","EXON2","Likely benign",,,"rs146526013",,,,"Pathogenicity is based on prediction data only. 0 out of 5 predictions were pathogenic.",,-1.582,"N",,,"0.004","B",0.168256,"N",1,"N",,"-0.194","N",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10132,0,0,11478,0,0,8526,0,0,6390,0,1,65596,0.0000152448,0,880,0,0,16496,0,1,119498,0.00000836834
416244,"chr19:10334852:C>T","S1PR2","NM_004230:p.Val244Ile","NM_004230:c.730G>A","EXON2","Likely benign",,,"rs146526013",,,,"Pathogenicity is based on prediction data only. 0 out of 5 predictions were pathogenic.",,-1.582,"N",,,"0.002","B",0.168256,"N",1,"N",,"-0.194","N",1,8600,0.000116279,0,4406,0,1,13006,0.0000768876,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416245,"chr19:10334853:G>A","S1PR2","NM_004230:p.Ile243Ile","NM_004230:c.729C>T","EXON2","Unknown significance",,,"rs148315102",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,2,8600,0.000232558,0,4406,0,2,13006,0.000153775,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10134,0,0,11480,0,0,8534,0,0,6404,0,6,65600,0.0000914634,0,882,0,0,16492,0,6,119526,0.0000501983
416246,"chr19:10334861:C>T","S1PR2","NM_004230:p.Val241Ile","NM_004230:c.721G>A","EXON2","Unknown significance",,,"rs141471894",,,,"This variant is a VUS because it does not have enough information.",,0.04,"N",,,"0.992","D",0.001257,"N",0.999993,"D",,"4.76","C",1,8600,0.000116279,0,4406,0,1,13006,0.0000768876,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10152,0,0,11486,0,0,8550,0,0,6402,0,3,65688,0.0000456704,0,880,0,0,16494,0,3,119652,0.0000250727
416247,"chr19:10334862:G>A","S1PR2","NM_004230:p.Gly240Gly","NM_004230:c.720C>T","EXON2","Unknown significance",,,"rs768428205",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10160,0,0,11484,0,2,8550,0.000233918,0,6408,0,0,65684,0,0,880,0,0,16496,0,2,119662,0.0000167137
416248,"chr19:10334865:T>C","S1PR2","NM_004230:p.Leu239Leu","NM_004230:c.717A>G","EXON2","Unknown significance",,,"rs150395684",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,0,8600,0,11,4406,0.0024966,11,13006,0.000845763,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,28,10176,0.00275157,1,11496,0.0000869868,0,8560,0,0,6418,0,0,65730,0,0,880,0,0,16498,0,29,119758,0.000242155
416249,"chr19:10334870:C>T","S1PR2","NM_004230:p.Val238Met","NM_004230:c.712G>A","EXON2","Unknown significance",,,"rs775103370",,,,"This variant is a VUS because it does not have enough information.",,0.935,"N",,,"1.0","D",0.000065,"D",1,"D",,"5.81","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10192,0,0,11502,0,0,8574,0,0,6414,0,1,65768,0.000015205,0,880,0,0,16496,0,1,119826,0.00000834543
416250,"chr19:10334871:G>A","S1PR2","NM_004230:p.Ile237Ile","NM_004230:c.711C>T","EXON2","Unknown significance",,,"rs765239276",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10190,0,0,11502,0,1,8574,0.000116632,0,6422,0,0,65776,0,0,878,0,1,16500,0.0000606061,2,119842,0.0000166886
416251,"chr19:10334874:G>A","S1PR2","NM_004230:p.Thr236Thr","NM_004230:c.708C>T","EXON2","Unknown significance",,,"rs750438454",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10200,0,0,11506,0,0,8586,0,0,6428,0,1,65794,0.000015199,0,882,0,0,16502,0,1,119898,0.00000834042
416252,"chr19:10334881:G>A","S1PR2","NM_004230:p.Thr234Met","NM_004230:c.701C>T","EXON2","Unknown significance",,,"rs762506865",,,,"This variant is a VUS because it does not have enough information.",,1.048,"C",,,"1.0","D",0.000091,"D",0.999999,"D",,"4.72","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10214,0,0,11510,0,0,8596,0,0,6430,0,0,65872,0,0,884,0,1,16498,0.0000606134,1,120004,0.00000833306
416253,"chr19:10334890:->TGTGACTCTGAGCAGTTTGCTTGATCTCTCTGAACTCACACCTCCATA","S1PR2",,"NM_004230:c.692_693insTATGGAGGTGTGAGTTCAGAGAGATCAAGCAAACTGCTCAGAGTCACA","EXON2","Unknown significance",,,"rs764685514",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416254,"chr19:10334890:A>G","S1PR2","NM_004230:p.Leu231Pro","NM_004230:c.692T>C","EXON2","Unknown significance",,,"rs766020432",,,,"This variant is a VUS because it does not have enough information.",,1.199,"C",,,"1.0","D",0.000002,"D",1,"D",,"5.81","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10222,0,0,11508,0,0,8596,0,0,6452,0,2,65918,0.0000303407,0,884,0,0,16504,0,2,120084,0.000016655
416255,"chr19:10334892:G>A","S1PR2","NM_004230:p.Ala230Ala","NM_004230:c.690C>T","EXON2","Unknown significance",,,"rs751157414",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416256,"chr19:10334894:C>T","S1PR2","NM_004230:p.Ala230Thr","NM_004230:c.688G>A","EXON2","Unknown significance",,,"rs754600043",,,,"This variant is a VUS because it does not have enough information.",,0.935,"N",,,"0.925","P",0.000008,"D",0.999803,"D",,"5.81","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416257,"chr19:10334898:C>T","S1PR2","NM_004230:p.Thr228Thr","NM_004230:c.684G>A","EXON2","Unknown significance",,,"rs780958549",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10230,0,0,11510,0,0,8602,0,0,6446,0,2,65954,0.0000303242,0,886,0,0,16502,0,2,120130,0.0000166486
416258,"chr19:10334899:G>A","S1PR2","NM_004230:p.Thr228Met","NM_004230:c.683C>T","EXON2","Unknown significance",,,"rs754150207",,,,"This variant is a VUS because it does not have enough information.",,1.048,"C",,,"1.0","D",0.000047,"D",0.999996,"D",,"5.81","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10238,0,0,11512,0,0,8604,0,0,6456,0,5,65972,0.0000757897,0,884,0,0,16502,0,5,120168,0.0000416084
416259,"chr19:10334904:C>T","S1PR2","NM_004230:p.Pro226Pro","NM_004230:c.678G>A","EXON2","Unknown significance",,,"rs757657597",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10228,0,0,11516,0,0,8604,0,0,6456,0,0,65974,0,0,882,0,1,16502,0.0000605987,1,120162,0.0000083221
416260,"chr19:10334905:G>A","S1PR2","NM_004230:p.Pro226Leu","NM_004230:c.677C>T","EXON2","Unknown significance",,,"rs561868200",,,,"This variant is a VUS because it does not have enough information.",,1.048,"C",,,"0.008","B",0.010485,"N",0.976707,"D",,"5.81","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,1,5008,0.000199681,0,10236,0,1,11520,0.0000868056,0,8606,0,0,6464,0,3,65990,0.0000454614,0,884,0,0,16500,0,4,120200,0.0000332779
416261,"chr19:10334909:C>T","S1PR2","NM_004230:p.Ala225Thr","NM_004230:c.673G>A","EXON2","Unknown significance",,,"rs143046723",,,,"This variant is a VUS because it does not have enough information.",,0.065,"N",,,"0.013","B",0.187156,"U",1,"N",,"4.78","C",5,8600,0.000581395,0,4406,0,5,13006,0.000384438,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10244,0,0,11520,0,0,8606,0,0,6454,0,21,66002,0.000318172,0,884,0,0,16504,0,21,120214,0.000174688
416262,"chr19:10334910:G>A","S1PR2","NM_004230:p.Ala224Ala","NM_004230:c.672C>T","EXON2","Benign",,,"rs73922356",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,0,8600,0,55,4406,0.012483,55,13006,0.00422882,,,,,,,,,,,,,,,,,,,,,,18,1322,0.0136,0,1006,0,0,694,0,0,1008,0,0,978,0,18,5008,0.00359425,116,10248,0.0113193,6,11524,0.000520653,0,8606,0,0,6466,0,6,65992,0.0000909201,0,884,0,0,16504,0,128,120224,0.00106468
416263,"chr19:10334915:T>C","S1PR2","NM_004230:p.Met223Val","NM_004230:c.667A>G","EXON2","Likely benign",,,"rs779999418",,,,"Pathogenicity is based on prediction data only. 0 out of 5 predictions were pathogenic.",,-0.339,"N",,,"0.0","B",0.00999,"N",1,"N",,"-0.835","N",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,10256,0.0000975039,0,11530,0,0,8614,0,0,6478,0,1,66046,0.000015141,0,884,0,0,16504,0,2,120312,0.0000166234
416264,"chr19:10334918:C>G","S1PR2","NM_004230:p.Asp222His","NM_004230:c.664G>C","EXON2","Unknown significance",,,"rs747191535",,,,"This variant is a VUS because it does not have enough information.",,0.935,"N",,,"0.896","P",0.007185,"N",0.999996,"D",,"5.81","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10254,0,0,11530,0,0,8614,0,0,6476,0,0,66056,0,0,882,0,3,16502,0.000181796,3,120314,0.0000249348
416265,"chr19:10334921:C>T","S1PR2","NM_004230:p.Ala221Thr","NM_004230:c.661G>A","EXON2","Likely benign",,,"rs544205933",,,,"Pathogenicity is based on prediction data only. 2 out of 5 predictions were pathogenic.",,0.071,"N",,,"0.545","P",0.051908,"N",1,"N",,"3.69","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,1,978,0.001,1,5008,0.000199681,1,10250,0.000097561,0,11530,0,0,8612,0,0,6480,0,1,66056,0.0000151387,0,882,0,1,16502,0.0000605987,3,120312,0.0000249352
416266,"chr19:10334922:G>A","S1PR2","NM_004230:p.His220His","NM_004230:c.660C>T","EXON2","Unknown significance",,,"rs776975550",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10252,0,1,11528,0.0000867453,2,8614,0.00023218,0,6490,0,0,66072,0,0,884,0,0,16502,0,3,120342,0.000024929
416267,"chr19:10334932:C>T","S1PR2","NM_004230:p.Arg217His","NM_004230:c.650G>A","EXON2","Unknown significance",,,"rs138962414",,,,"This variant is a VUS because it does not have enough information.",,0.935,"N",,,"1.0","D",0.004923,"N",0.999976,"D",,"5.81","C",2,8600,0.000232558,0,4406,0,2,13006,0.000153775,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10254,0,0,11534,0,0,8620,0,0,6486,0,3,66064,0.0000454105,0,882,0,1,16498,0.0000606134,4,120338,0.0000332397
416268,"chr19:10334933:G>A","S1PR2","NM_004230:p.Arg217Cys","NM_004230:c.649C>T","EXON2","Unknown significance",,,"rs769736633",,,,"This variant is a VUS because it does not have enough information.",,1.048,"C",,,"1.0","D",0.004923,"N",1,"D",,"5.81","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10260,0,0,11538,0,0,8622,0,0,6494,0,1,66086,0.0000151318,0,886,0,0,16498,0,1,120384,0.00000830675
416269,"chr19:10334939:C>T","S1PR2","NM_004230:p.Val215Met","NM_004230:c.643G>A","EXON2","Unknown significance",,,"rs773248254",,,,"This variant is a VUS because it does not have enough information.",,0.935,"N",,,"0.999","D",0.000426,"D",0.989163,"D",,"5.81","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,10278,0.0000972952,0,11542,0,0,8624,0,0,6504,0,1,66110,0.0000151263,0,886,0,0,16502,0,2,120446,0.000016605
416270,"chr19:10334940:G>A","S1PR2","NM_004230:p.Cys214Cys","NM_004230:c.642C>T","EXON2","Benign",,,"rs79482117",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,0,8600,0,193,4406,0.0438039,193,13006,0.0148393,,,,,,,,,,,,,,,,,,,,,,47,1322,0.0356,0,1006,0,5,694,0.0072,0,1008,0,0,978,0,52,5008,0.0103834,467,10282,0.0454192,19,11544,0.00164588,0,8626,0,0,6508,0,2,66108,0.0000302535,1,884,0.00113122,1,16502,0.0000605987,490,120454,0.00406794
416271,"chr19:10334950:C>T","S1PR2","NM_004230:p.Arg211His","NM_004230:c.632G>A","EXON2","Likely benign",,,"rs141230424",,,,"Pathogenicity is based on prediction data only. 2 out of 5 predictions were pathogenic.",,0.065,"N",,,"0.087","B",0.000189,"N",0.999848,"D",,"4.78","C",1,8600,0.000116279,0,4406,0,1,13006,0.0000768876,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,0,10278,0,0,11550,0,0,8626,0,0,6520,0,8,66166,0.000120908,0,884,0,2,16504,0.000121183,10,120528,0.0000829683
416272,"chr19:10334951:G>A","S1PR2","NM_004230:p.Arg211Cys","NM_004230:c.631C>T","EXON2","Unknown significance",,,"rs146365556",,,,"This variant is a VUS because it does not have enough information.",,1.048,"C",,,"0.998","D",0.000189,"D",1,"D",,"5.81","C",0,8600,0,1,4406,0.000226963,1,13006,0.0000768876,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416273,"chr19:10334954:C>T","S1PR2","NM_004230:p.Val210Met","NM_004230:c.628G>A","EXON2","Likely benign",,,"rs773723376",,,,"Pathogenicity is based on prediction data only. 2 out of 5 predictions were pathogenic.",,-0.324,"N",,,"0.848","P",0.04053,"N",0.974752,"D",,"-2.61","N",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,10296,0.0000971251,0,11552,0,0,8626,0,0,6520,0,0,66172,0,0,886,0,2,16508,0.000121153,3,120560,0.0000248839
416274,"chr19:10334955:G>A","S1PR2","NM_004230:p.Tyr209Tyr","NM_004230:c.627C>T","EXON2","Unknown significance",,,"rs145137562",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,0,8600,0,1,4406,0.000226963,1,13006,0.0000768876,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,2,10298,0.000194212,0,11552,0,0,8626,0,0,6522,0,1,66168,0.000015113,0,886,0,0,16508,0,3,120560,0.0000248839
416275,"chr19:10334963:C>T","S1PR2","NM_004230:p.Ala207Thr","NM_004230:c.619G>A","EXON2","Likely benign",,,"rs767044475",,,,"Pathogenicity is based on prediction data only. 1 out of 5 predictions were pathogenic.",,0.935,"N",,,"0.002","B",0.085872,"N",0.9999,"N",,"5.81","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10302,0,0,11554,0,0,8624,0,0,6534,0,1,66186,0.0000151089,0,884,0,0,16506,0,1,120590,0.00000829256
416276,"chr19:10334966:C>G","S1PR2","NM_004230:p.Val206Leu","NM_004230:c.616G>C","EXON2","Unknown significance",,,"rs201947575",,,,"This variant is a VUS because it does not have enough information.",,0.935,"N",,,"0.258","B",0.000728,"D",0.999995,"D",,"5.81","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416277,"chr19:10334967:G>A","S1PR2","NM_004230:p.Ile205Ile","NM_004230:c.615C>T","EXON2","Unknown significance",,,"rs200948899",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,0,10306,0,1,11552,0.0000865651,0,8622,0,0,6536,0,1,66194,0.0000151071,0,888,0,0,16508,0,2,120606,0.0000165829
416278,"chr19:10334980:A>G","S1PR2","NM_004230:p.Ile201Thr","NM_004230:c.602T>C","EXON2","Unknown significance",,,"rs757567998",,,,"This variant is a VUS because it does not have enough information.",,1.199,"C",,,"0.999","D",0,"D",1,"D",,"5.66","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10312,0,0,11554,0,0,8628,0,0,6544,0,2,66232,0.0000301969,0,888,0,0,16506,0,2,120664,0.000016575
416279,"chr19:10334985:G>A","S1PR2","NM_004230:p.Ser199Ser","NM_004230:c.597C>T","EXON2","Unknown significance",,,"rs765620667",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10312,0,0,11554,0,0,8630,0,0,6550,0,0,66238,0,0,888,0,1,16510,0.0000605694,1,120682,0.00000828624
416280,"chr19:10335002:C>A","S1PR2","NM_004230:p.Val194Leu","NM_004230:c.580G>T","EXON2","Unknown significance",,,"rs750859739",,,,"This variant is a VUS because it does not have enough information.",,0.935,"N",,,"0.998","D",0.000001,"D",0.999996,"D",,"5.66","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10312,0,0,11556,0,1,8632,0.000115848,0,6560,0,0,66234,0,0,892,0,0,16508,0,1,120694,0.00000828542
416281,"chr19:10335003:G>A","S1PR2","NM_004230:p.Cys193Cys","NM_004230:c.579C>T","EXON2","Unknown significance",,,"rs758916106",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10306,0,0,11556,0,0,8632,0,0,6560,0,1,66234,0.000015098,0,892,0,0,16508,0,1,120688,0.00000828583
416282,"chr19:10335004:C>A","S1PR2","NM_004230:p.Cys193Phe","NM_004230:c.578G>T","EXON2","Likely benign",,,"rs780666522",,,,"Pathogenicity is based on prediction data only. 2 out of 5 predictions were pathogenic.",,0.935,"N",,,"0.0","B",0.002227,"N",0.999142,"D",,"3.43","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10308,0,0,11554,0,0,8632,0,0,6564,0,2,66230,0.0000301978,0,892,0,0,16510,0,2,120690,0.0000165714
416283,"chr19:10335008:G>A","S1PR2","NM_004230:p.Leu192Leu","NM_004230:c.574C>T","EXON2","Unknown significance",,,"rs548754912",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2,1322,0.0015,0,1006,0,0,694,0,0,1008,0,0,978,0,2,5008,0.000399361,4,10302,0.000388274,0,11558,0,0,8634,0,0,6562,0,0,66218,0,0,890,0,0,16510,0,4,120674,0.0000331472
416284,"chr19:10335011:C>A","S1PR2","NM_004230:p.Val191Leu","NM_004230:c.571G>T","EXON2","Unknown significance",,,"rs755137611",,,,"This variant is a VUS because it does not have enough information.",,0.935,"N",,,"0.122","B",0.000065,"D",0.998262,"D",,"5.66","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416285,"chr19:10335012:A>G","S1PR2","NM_004230:p.Tyr190Tyr","NM_004230:c.570T>C","EXON2","Unknown significance",,,"rs142570783",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,3,8600,0.000348837,1,4406,0.000226963,4,13006,0.00030755,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,10304,0.0000970497,0,11556,0,0,8634,0,0,6566,0,7,66216,0.000105715,0,890,0,0,16508,0,8,120674,0.0000662943
416286,"chr19:10335017:G>C","S1PR2","NM_004230:p.His189Asp","NM_004230:c.565C>G","EXON2","Likely benign",,,"rs150504911",,,,"Pathogenicity is based on prediction data only. 0 out of 5 predictions were pathogenic.",,0.1,"N",,,"0.0","B",0.305469,"N",1,"N",,"-1.34","N",3,8600,0.000348837,0,4406,0,3,13006,0.000230663,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10306,0,0,11552,0,0,8630,0,0,6568,0,11,66196,0.000166173,0,890,0,0,16510,0,11,120652,0.0000911713
416287,"chr19:10335022:G>A","S1PR2","NM_004230:p.Ala187Val","NM_004230:c.560C>T","EXON2","Unknown significance",,,"rs528715848",,,,"This variant is a VUS because it does not have enough information.",,1.048,"C",,,"0.193","B",0.001607,"N",0.997649,"D",,"5.66","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416288,"chr19:10335023:C>T","S1PR2","NM_004230:p.Ala187Thr","NM_004230:c.559G>A","EXON2","Likely benign",,,"rs375315200",,,,"Pathogenicity is based on prediction data only. 2 out of 5 predictions were pathogenic.",,0.065,"N",,,"0.004","B",0.001607,"N",0.802601,"D",,"3.5","C",1,8600,0.000116279,0,4406,0,1,13006,0.0000768876,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416289,"chr19:10335024:G>A","S1PR2","NM_004230:p.Tyr186Tyr","NM_004230:c.558C>T","EXON2","Unknown significance",,,"rs199954220",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,1,8600,0.000116279,0,4406,0,1,13006,0.0000768876,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,0,10306,0,0,11546,0,8,8626,0.000927429,0,6570,0,5,66186,0.0000755447,0,890,0,0,16510,0,13,120634,0.000107764
416290,"chr19:10335041:T>C","S1PR2","NM_004230:p.Thr181Ala","NM_004230:c.541A>G","EXON2","Unknown significance",,,"rs773156107",,,,"This variant is a VUS because it does not have enough information.",,1.061,"C",,,"0.122","B",0.000042,"D",0.99875,"D",,"5.66","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10292,0,0,11542,0,0,8614,0,0,6560,0,0,65990,0,0,890,0,1,16506,0.000060584,1,120394,0.00000830606
416291,"chr19:10335053:C>T","S1PR2","NM_004230:p.Glu177Lys","NM_004230:c.529G>A","EXON2","Unknown significance",,,"rs139476990",,,,"This variant is a VUS because it does not have enough information.",,0.892,"N",,,"0.729","P",0.149061,"N",0.998016,"D",,"5.57","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10278,0,0,11544,0,0,8610,0,0,6562,0,3,65894,0.0000455277,0,890,0,0,16506,0,3,120284,0.000024941
416292,"chr19:10335054:G>A","S1PR2","NM_004230:p.Leu176Leu","NM_004230:c.528C>T","EXON2","Unknown significance",,,"rs770771070",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10270,0,0,11542,0,1,8610,0.000116144,0,6562,0,0,65904,0,0,892,0,1,16506,0.000060584,2,120286,0.000016627
416293,"chr19:10335070:T>C","S1PR2","NM_004230:p.Asn171Ser","NM_004230:c.512A>G","EXON2","Unknown significance",,,"rs774388647",,,,"This variant is a VUS because it does not have enough information.",,1.011,"C",,,"1.0","D",0,"D",0.999999,"D",,"5.46","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10280,0,0,11542,0,0,8608,0,0,6566,0,0,65886,0,0,894,0,1,16500,0.0000606061,1,120276,0.00000831421
416294,"chr19:10335083:T>C","S1PR2","NM_004230:p.Ile167Val","NM_004230:c.499A>G","EXON2","Unknown significance",,,"rs758945809",,,,"This variant is a VUS because it does not have enough information.",,1.011,"C",,,"0.37","B",0.000006,"N",0.99993,"D",,"4.44","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10278,0,0,11546,0,0,8600,0,19,6578,0.00288842,2,65876,0.0000303601,1,896,0.00111607,0,16502,0,22,120276,0.000182913
416295,"chr19:10335087:C>G","S1PR2","NM_004230:p.Leu165Leu","NM_004230:c.495G>C","EXON2","Unknown significance",,,"rs746050596",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416296,"chr19:10335095:C>G","S1PR2","NM_004230:p.Gly163Arg","NM_004230:c.487G>C","EXON2","Unknown significance",,,"rs767074437",,,,"This variant is a VUS because it does not have enough information.",,0.892,"N",,,"1.0","D",0,"D",1,"D",,"5.46","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10276,0,0,11544,0,0,8594,0,0,6578,0,1,65836,0.0000151893,0,894,0,0,16502,0,1,120224,0.00000831781
416297,"chr19:10335096:G>A","S1PR2","NM_004230:p.Leu162Leu","NM_004230:c.486C>T","EXON2","Unknown significance",,,"rs375693128",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,1,8600,0.000116279,0,4406,0,1,13006,0.0000768876,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,10274,0.0000973331,0,11544,0,0,8598,0,0,6580,0,1,65846,0.000015187,0,894,0,1,16502,0.0000605987,3,120238,0.0000249505
416298,"chr19:10335102:C>T","S1PR2","NM_004230:p.Leu160Leu","NM_004230:c.480G>A","EXON2","Unknown significance",,,"rs144510483",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,0,8600,0,16,4406,0.00363141,16,13006,0.0012302,,,,,,,,,,,,,,,,,,,,,,5,1322,0.0038,0,1006,0,0,694,0,0,1008,0,0,978,0,5,5008,0.000998403,41,10278,0.0039891,4,11544,0.0003465,0,8602,0,0,6580,0,0,65856,0,0,896,0,0,16498,0,45,120254,0.000374208
416299,"chr19:10335102:C>G","S1PR2","NM_004230:p.Leu160Leu","NM_004230:c.480G>C","EXON2","Unknown significance",,,"rs144510483",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10278,0,0,11544,0,0,8602,0,0,6580,0,0,65856,0,0,896,0,1,16498,0.0000606134,1,120254,0.00000831573
416300,"chr19:10335105:C>T","S1PR2","NM_004230:p.Ser159Ser","NM_004230:c.477G>A","EXON2","Benign",,,"rs200965528",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,6,978,0.0061,7,5008,0.00139776,11,10270,0.00107108,1,11544,0.0000866251,1,8604,0.000116225,0,6580,0,2,65844,0.0000303748,1,896,0.00111607,162,16498,0.00981937,178,120236,0.00148042
416301,"chr19:10335106:G>A","S1PR2","NM_004230:p.Ser159Leu","NM_004230:c.476C>T","EXON2","Unknown significance",,,"rs758826475",,,,"This variant is a VUS because it does not have enough information.",,0.998,"C",,,"0.996","D",0.000021,"D",1,"D",,"5.46","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,10272,0.000097352,0,11546,0,0,8604,0,0,6582,0,0,65852,0,0,896,0,0,16500,0,1,120252,0.00000831587
416302,"chr19:10335108:G>A","S1PR2","NM_004230:p.Ile158Ile","NM_004230:c.474C>T","EXON2","Unknown significance",,,"rs766761324",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10270,0,1,11546,0.0000866101,0,8604,0,0,6582,0,0,65858,0,0,896,0,0,16498,0,1,120254,0.00000831573
416303,"chr19:10335109:A>G","S1PR2","NM_004230:p.Ile158Thr","NM_004230:c.473T>C","EXON2","Unknown significance",,,"rs752132394",,,,"This variant is a VUS because it does not have enough information.",,1.14,"C",,,"0.028","B",0.002931,"N",0.997672,"D",,"5.46","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10276,0,0,11546,0,0,8604,0,0,6582,0,0,65852,0,0,896,0,1,16500,0.0000606061,1,120256,0.00000831559
416304,"chr19:10335117:C>T","S1PR2","NM_004230:p.Ser155Ser","NM_004230:c.465G>A","EXON2","Unknown significance",,,"rs571515815",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,0,10278,0,1,11542,0.0000866401,2,8606,0.000232396,0,6590,0,0,65862,0,0,894,0,0,16502,0,3,120274,0.000024943
416305,"chr19:10335118:G>A","S1PR2","NM_004230:p.Ser155Leu","NM_004230:c.464C>T","EXON2","Unknown significance",,,"rs781340607",,,,"This variant is a VUS because it does not have enough information.",,0.998,"C",,,"0.859","P",0.000011,"D",0.999608,"D",,"4.39","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,10278,0.0000972952,0,11542,0,0,8608,0,0,6590,0,0,65858,0,0,894,0,0,16502,0,1,120272,0.00000831449
416306,"chr19:10335121:G>A","S1PR2","NM_004230:p.Ala154Val","NM_004230:c.461C>T","EXON2","Unknown significance",,,"rs748326799",,,,"This variant is a VUS because it does not have enough information.",,0.998,"C",,,"1.0","D",0,"D",1,"D",,"5.46","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10284,0,0,11542,0,0,8608,0,0,6590,0,1,65862,0.0000151833,0,894,0,0,16498,0,1,120278,0.00000831407
416307,"chr19:10335126:G>A","S1PR2","NM_004230:p.Ile152Ile","NM_004230:c.456C>T","EXON2","Unknown significance",,,"rs539019136",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,1,10286,0.0000972195,0,11540,0,2,8606,0.000232396,0,6588,0,1,65860,0.0000151837,0,894,0,0,16504,0,4,120278,0.0000332563
416308,"chr19:10335127:A>G","S1PR2","NM_004230:p.Ile152Thr","NM_004230:c.455T>C","EXON2","Unknown significance",,,"rs778208496",,,,"This variant is a VUS because it does not have enough information.",,1.14,"C",,,"0.994","D",0.000265,"D",1,"D",,"5.46","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10286,0,0,11542,0,0,8606,0,0,6592,0,1,65864,0.0000151828,0,894,0,0,16504,0,1,120288,0.00000831338
416309,"chr19:10335129:G>A","S1PR2","NM_004230:p.Leu151Leu","NM_004230:c.453C>T","EXON2","Unknown significance",,,"rs749062515",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10282,0,0,11542,0,0,8606,0,0,6590,0,1,65862,0.0000151833,0,894,0,0,16504,0,1,120280,0.00000831393
416310,"chr19:10335133:A>T","S1PR2","NM_004230:p.Leu150Gln","NM_004230:c.449T>A","EXON2","Unknown significance",,,"rs770806486",,,,"This variant is a VUS because it does not have enough information.",,1.14,"C",,,"0.864","P",0.007584,"N",0.999686,"D",,"4.38","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10284,0,0,11542,0,0,8608,0,0,6588,0,1,65866,0.0000151823,0,894,0,0,16504,0,1,120286,0.00000831352
416311,"chr19:10335142:C>A","S1PR2","NM_004230:p.Arg147Leu","NM_004230:c.440G>T","EXON2","Unknown significance",,,"rs774105619",,,,"This variant is a VUS because it does not have enough information.",,0.892,"N",,,"1.0","D",0,"D",1,"D",,"5.46","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10284,0,1,11540,0.0000866551,0,8604,0,0,6582,0,0,65828,0,0,892,0,0,16502,0,1,120232,0.00000831725
416312,"chr19:10335142:C>T","S1PR2","NM_004230:p.Arg147His","NM_004230:c.440G>A","EXON2","Unknown significance",,,"rs774105619",,,,"This variant is a VUS because it does not have enough information.",,0.892,"N",,,"1.0","D",0,"D",1,"D",,"5.46","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10284,0,0,11540,0,1,8604,0.000116225,0,6582,0,0,65828,0,0,892,0,0,16502,0,1,120232,0.00000831725
416313,"chr19:10335143:G>A","S1PR2","NM_004230:p.Arg147Cys","NM_004230:c.439C>T","EXON2","Unknown significance",,,"rs771416712",,,,"This variant is a VUS because it does not have enough information.",,0.998,"C",,,"1.0","D",0,"D",1,"D",,"5.46","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10280,0,0,11542,0,0,8602,0,0,6584,0,1,65816,0.0000151939,0,894,0,0,16504,0,1,120222,0.00000831795
416314,"chr19:10335153:G>A","S1PR2","NM_004230:p.Asp143Asp","NM_004230:c.429C>T","EXON2","Unknown significance",,,"rs774990809",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10276,0,1,11538,0.0000866701,0,8600,0,0,6582,0,0,65764,0,0,894,0,0,16506,0,1,120160,0.00000832224
416315,"chr19:10335155:C>T","S1PR2","NM_004230:p.Asp143Asn","NM_004230:c.427G>A","EXON2","Unknown significance",,,"rs760232470",,,,"This variant is a VUS because it does not have enough information.",,0.892,"N",,,"0.811","P",0.018772,"U",0.995674,"D",,"5.46","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10276,0,1,11536,0.0000866852,0,8600,0,0,6580,0,0,65742,0,0,892,0,0,16504,0,1,120130,0.00000832432
416316,"chr19:10335156:G>A","S1PR2","NM_004230:p.Ser142Ser","NM_004230:c.426C>T","EXON2","Unknown significance",,,"rs768290233",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,10278,0.0000972952,0,11536,0,0,8600,0,0,6582,0,1,65732,0.0000152133,0,892,0,1,16504,0.0000605914,3,120124,0.0000249742
416317,"chr19:10335171:G>A","S1PR2","NM_004230:p.Val137Val","NM_004230:c.411C>T","EXON2","Unknown significance",,,"rs147860417",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,1,8600,0.000116279,0,4406,0,1,13006,0.0000768876,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10272,0,0,11534,0,0,8604,0,0,6574,0,3,65720,0.0000456482,0,892,0,0,16502,0,3,120098,0.0000249796
416318,"chr19:10335176:->TGGCAATGGCCACGTGGCGCTCAA","S1PR2",,"NM_004230:c.406_407insTTGAGCGCCACGTGGCCATTGCCA","EXON2","Unknown significance",,,"rs750023590",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416319,"chr19:10335186:C>T","S1PR2","NM_004230:p.Val132Val","NM_004230:c.396G>A","EXON2","Unknown significance",,,"rs763257359",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,10232,0.0000977326,0,11530,0,0,8604,0,0,6568,0,0,65672,0,0,892,0,0,16504,0,1,120002,0.00000833319
416320,"chr19:10335187:A>G","S1PR2","NM_004230:p.Val132Ala","NM_004230:c.395T>C","EXON2","Unknown significance",,,"rs766800341",,,,"This variant is a VUS because it does not have enough information.",,1.14,"C",,,"0.961","D",0.000357,"D",0.999937,"D",,"5.46","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10228,0,0,11530,0,0,8602,0,0,6568,0,1,65670,0.0000152277,0,892,0,0,16504,0,1,119994,0.00000833375
416321,"chr19:10335189:G>A","S1PR2","NM_004230:p.His131His","NM_004230:c.393C>T","EXON2","Unknown significance",,,"rs554534393",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,0,10230,0,0,11530,0,0,8602,0,0,6564,0,1,65676,0.0000152263,0,892,0,0,16502,0,1,119996,0.00000833361
416322,"chr19:10335191:G>A","S1PR2","NM_004230:p.His131Tyr","NM_004230:c.391C>T","EXON2","Unknown significance",,,"rs760106219",,,,"This variant is a VUS because it does not have enough information.",,0.998,"C",,,"0.0","B",0.020893,"N",0.525576,"D",,"5.46","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10222,0,0,11528,0,0,8604,0,0,6558,0,1,65620,0.0000152393,0,892,0,0,16502,0,1,119926,0.00000833848
416323,"chr19:10335194:G>A","S1PR2","NM_004230:p.Arg130Cys","NM_004230:c.388C>T","EXON2","Unknown significance",,,"rs200439929",,,,"This variant is a VUS because it does not have enough information.",,-0.428,"N",,,"1.0","D",0,"D",1,"D",,"3.25","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,2,10224,0.000195618,0,11526,0,0,8598,0,0,6554,0,0,65610,0,0,892,0,0,16502,0,2,119906,0.0000166797
416324,"chr19:10335203:C>T","S1PR2","NM_004230:p.Ala127Thr","NM_004230:c.379G>A","EXON2","Unknown significance",,,"rs752820109",,,,"This variant is a VUS because it does not have enough information.",,0.892,"N",,,"1.0","D",0,"D",1,"D",,"5.46","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10220,0,0,11528,0,0,8602,0,0,6546,0,1,65604,0.000015243,0,890,0,1,16500,0.0000606061,2,119890,0.000016682
416325,"chr19:10335204:G>A","S1PR2","NM_004230:p.Ile126Ile","NM_004230:c.378C>T","EXON2","Unknown significance",,,"rs756303739",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10230,0,0,11522,0,0,8598,0,0,6552,0,1,65610,0.0000152416,0,892,0,0,16496,0,1,119900,0.00000834028
416326,"chr19:10335207:G>A","S1PR2","NM_004230:p.Ala125Ala","NM_004230:c.375C>T","EXON2","Unknown significance",,,"rs778120707",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10222,0,0,11526,0,0,8598,0,0,6554,0,1,65618,0.0000152397,0,892,0,0,16504,0,1,119914,0.00000833931
416327,"chr19:10335231:C>G","S1PR2","NM_004230:p.Ser117Ser","NM_004230:c.351G>C","EXON2","Unknown significance",,,"rs754134254",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10218,0,0,11526,0,0,8590,0,0,6536,0,0,65522,0,0,890,0,1,16500,0.0000606061,1,119782,0.0000083485
416328,"chr19:10335231:C>T","S1PR2","NM_004230:p.Ser117Ser","NM_004230:c.351G>A","EXON2","Unknown significance",,,"rs754134254",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10218,0,0,11526,0,0,8590,0,0,6536,0,0,65522,0,0,890,0,1,16500,0.0000606061,1,119782,0.0000083485
416329,"chr19:10335237:C>T","S1PR2","NM_004230:p.Thr115Thr","NM_004230:c.345G>A","EXON2","Unknown significance",,,"rs778774106",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10202,0,1,11522,0.0000867905,0,8588,0,0,6528,0,0,65556,0,0,892,0,0,16496,0,1,119784,0.00000834836
416330,"chr19:10335249:A>G","S1PR2","NM_004230:p.Ser111Ser","NM_004230:c.333T>C","EXON2","Unknown significance",,,"rs745577083",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10220,0,0,11520,0,0,8590,0,24,6544,0.00366748,3,65582,0.0000457443,1,890,0.0011236,0,16500,0,28,119846,0.000233633
416331,"chr19:10335254:C>T","S1PR2","NM_004230:p.Gly110Ser","NM_004230:c.328G>A","EXON2","Unknown significance",,,"rs772030354",,,,"This variant is a VUS because it does not have enough information.",,0.892,"N",,,"1.0","D",0,"D",1,"D",,"5.46","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10208,0,0,11518,0,0,8590,0,0,6544,0,1,65596,0.0000152448,0,890,0,0,16500,0,1,119846,0.00000834404
416332,"chr19:10335273:C>A","S1PR2","NM_004230:p.Val103Val","NM_004230:c.309G>T","EXON2","Unknown significance",,,"rs780028833",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10208,0,1,11514,0.0000868508,0,8580,0,0,6542,0,0,65642,0,0,886,0,0,16498,0,1,119870,0.00000834237
416333,"chr19:10335273:C>T","S1PR2","NM_004230:p.Val103Val","NM_004230:c.309G>A","EXON2","Unknown significance",,,"rs780028833",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,10208,0.0000979624,0,11514,0,0,8580,0,0,6542,0,0,65642,0,0,886,0,0,16498,0,1,119870,0.00000834237
416334,"chr19:10335279:C>T","S1PR2","NM_004230:p.Thr101Thr","NM_004230:c.303G>A","EXON2","Unknown significance",,,"rs372171605",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,0,8600,0,1,4406,0.000226963,1,13006,0.0000768876,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,10210,0.0000979432,0,11514,0,0,8580,0,0,6544,0,0,65668,0,0,888,0,0,16498,0,1,119902,0.00000834014
416335,"chr19:10335280:G>A","S1PR2","NM_004230:p.Thr101Met","NM_004230:c.302C>T","EXON2","Unknown significance",,,"rs776229108",,,,"This variant is a VUS because it does not have enough information.",,0.998,"C",,,"0.981","D",0.002339,"N",0.999855,"D",,"5.46","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10210,0,0,11516,0,3,8578,0.000349732,0,6548,0,0,65658,0,0,888,0,0,16498,0,3,119896,0.0000250217
416336,"chr19:10335285:C>T","S1PR2","NM_004230:p.Arg99Arg","NM_004230:c.297G>A","EXON2","Unknown significance",,,"rs761534939",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10210,0,0,11516,0,1,8580,0.00011655,0,6550,0,0,65700,0,0,890,0,0,16498,0,1,119944,0.00000833722
416337,"chr19:10335291:C>T","S1PR2","NM_004230:p.Thr97Thr","NM_004230:c.291G>A","EXON2","Unknown significance",,,"rs768094283",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10224,0,0,11510,0,0,8578,0,0,6548,0,1,65710,0.0000152184,0,890,0,0,16492,0,1,119952,0.00000833667
416338,"chr19:10335296:CAGAGC>-","S1PR2",,"NM_004230:c.286_293delGCTCTG","EXON2","Unknown significance",,,"rs755623288",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416339,"chr19:10335308:G>A","S1PR2","NM_004230:p.Leu92Phe","NM_004230:c.274C>T","EXON2","Unknown significance",,,"rs774768484",,,,"This variant is a VUS because it does not have enough information.",,0.998,"C",,,"1.0","D",0.000002,"D",1,"D",,"5.46","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,10220,0.0000978474,0,11520,0,0,8586,0,0,6560,0,0,65722,0,0,892,0,0,16504,0,1,120004,0.00000833306
416340,"chr19:10335323:C>A","S1PR2","NM_004230:p.Val87Leu","NM_004230:c.259G>T","EXON2","Likely benign",,,"rs759886451",,,,"Pathogenicity is based on prediction data only. 1 out of 5 predictions were pathogenic.",,-0.389,"N",,,"0.01","B",0.05915,"N",0.891827,"D",,"-2.75","N",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416341,"chr19:10335323:C>T","S1PR2","NM_004230:p.Val87Ile","NM_004230:c.259G>A","EXON2","Likely benign",,,"rs759886451",,,,"Pathogenicity is based on prediction data only. 1 out of 5 predictions were pathogenic.",,-0.389,"N",,,"0.0","B",0.05915,"N",0.700701,"D",,"-2.75","N",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416342,"chr19:10335324:G>A","S1PR2","NM_004230:p.Phe86Phe","NM_004230:c.258C>T","EXON2","Unknown significance",,,"rs141451923",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,1,8600,0.000116279,0,4404,0,1,13004,0.0000768994,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9950,0,0,11494,0,0,8572,0,0,6550,0,6,65024,0.0000922736,0,882,0,0,16506,0,6,118978,0.0000504295
416343,"chr19:10335332:C>T","S1PR2","NM_004230:p.Val84Met","NM_004230:c.250G>A","EXON2","Unknown significance",,,"rs369608498",,,,"This variant is a VUS because it does not have enough information.",,-1.003,"N",,,"0.998","D",0.048221,"N",0.780551,"D",,"4.23","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10074,0,1,11504,0.0000869263,0,8582,0,1,6580,0.000151976,0,65448,0,0,888,0,0,16508,0,2,119584,0.0000167246
416344,"chr19:10335333:G>A","S1PR2","NM_004230:p.Gly83Gly","NM_004230:c.249C>T","EXON2","Benign",,,"rs73922357",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,0,8598,0,49,4406,0.0111212,49,13004,0.00376807,,,,,,,,,,,,,,,,,,,,,,13,1322,0.0098,0,1006,0,0,694,0,0,1008,0,0,978,0,13,5008,0.00259585,108,9324,0.011583,5,11434,0.000437292,0,8522,0,0,6124,0,2,63294,0.0000315986,0,844,0,1,16504,0.0000605914,116,116046,0.000999604
416345,"chr19:10335347:C>T","S1PR2","NM_004230:p.Asp79Asn","NM_004230:c.235G>A","EXON2","Unknown significance",,,"rs754046468",,,,"This variant is a VUS because it does not have enough information.",,0.892,"N",,,"1.0","D",0,"D",1,"D",,"5.26","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10226,0,1,11534,0.0000867002,0,8612,0,0,6598,0,0,65858,0,0,898,0,0,16510,0,1,120236,0.00000831698
416346,"chr19:10335348:G>A","S1PR2","NM_004230:p.Ser78Ser","NM_004230:c.234C>T","EXON2","Unknown significance",,,"rs757513633",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416347,"chr19:10335351:G>T","S1PR2","NM_004230:p.Ala77Ala","NM_004230:c.231C>A","EXON2","Unknown significance",,,"rs750986918",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416348,"chr19:10335352:G>A","S1PR2","NM_004230:p.Ala77Val","NM_004230:c.230C>T","EXON2","Unknown significance",,,"rs779058016",,,,"This variant is a VUS because it does not have enough information.",,0.998,"C",,,"0.704","P",0.002014,"N",0.981468,"D",,"4.05","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10240,0,5,11542,0.0004332,0,8612,0,0,6606,0,0,65956,0,0,898,0,0,16512,0,5,120366,0.00004154
416349,"chr19:10335353:C>T","S1PR2","NM_004230:p.Ala77Thr","NM_004230:c.229G>A","EXON2","Unknown significance",,,"rs750224099",,,,"This variant is a VUS because it does not have enough information.",,0.892,"N",,,"0.992","D",0.002014,"N",0.974907,"D",,"3.99","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10248,0,0,11546,0,0,8614,0,0,6604,0,4,65974,0.0000606299,0,898,0,0,16512,0,4,120396,0.0000332237
416350,"chr19:10335354:G>A","S1PR2","NM_004230:p.Ala76Ala","NM_004230:c.228C>T","EXON2","Unknown significance",,,"rs201361490",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,1,5008,0.000199681,0,10268,0,9,11546,0.000779491,0,8612,0,1,6606,0.000151378,0,66004,0,0,898,0,1,16512,0.000060562,11,120446,0.0000913272
416351,"chr19:10335360:G>C","S1PR2","NM_004230:p.Asn74Lys","NM_004230:c.222C>G","EXON2","Unknown significance",,,"rs779941001",,,,"This variant is a VUS because it does not have enough information.",,0.998,"C",,,"1.0","D",0,"D",0.999999,"D",,"2.95","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10296,0,0,11548,0,0,8618,0,0,6610,0,2,66114,0.0000302508,0,900,0,0,16512,0,2,120598,0.000016584
416352,"chr19:10335365:C>T","S1PR2","NM_004230:p.Gly73Ser","NM_004230:c.217G>A","EXON2","Unknown significance",,,"rs756238075",,,,"This variant is a VUS because it does not have enough information.",,0.892,"N",,,"1.0","D",0,"D",1,"D",,"5.09","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416353,"chr19:10335366:C>T","S1PR2","NM_004230:p.Leu72Leu","NM_004230:c.216G>A","EXON2","Unknown significance",,,"rs746982563",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10312,0,0,11558,0,0,8624,0,0,6610,0,1,66202,0.0000151053,0,902,0,0,16512,0,1,120720,0.00000828363
416354,"chr19:10335375:G>A","S1PR2","NM_004230:p.Tyr69Tyr","NM_004230:c.207C>T","EXON2","Unknown significance",,,"rs768089970",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10344,0,0,11570,0,0,8628,0,0,6614,0,1,66314,0.0000150798,0,904,0,0,16512,0,1,120886,0.00000827226
416355,"chr19:10335377:A>G","S1PR2","NM_004230:p.Tyr69His","NM_004230:c.205T>C","EXON2","Unknown significance",,,"rs780697765",,,,"This variant is a VUS because it does not have enough information.",,1.14,"C",,,"0.999","D",0.000035,"D",0.999957,"D",,"5.09","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10346,0,0,11570,0,0,8628,0,0,6614,0,0,66336,0,0,904,0,1,16512,0.000060562,1,120910,0.00000827061
416356,"chr19:10335379:A>G","S1PR2","NM_004230:p.Met68Thr","NM_004230:c.203T>C","EXON2","Unknown significance",,,"rs747674218",,,,"This variant is a VUS because it does not have enough information.",,1.14,"C",,,"0.659","P",0,"D",0.999997,"D",,"5.09","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10350,0,0,11570,0,0,8628,0,0,6614,0,1,66354,0.0000150707,0,904,0,0,16512,0,1,120932,0.00000826911
416357,"chr19:10335383:C>G","S1PR2","NM_004230:p.Ala67Pro","NM_004230:c.199G>C","EXON2","Unknown significance",,,"rs769482969",,,,"This variant is a VUS because it does not have enough information.",,0.892,"N",,,"0.64","P",0,"D",1,"D",,"5.09","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10350,0,0,11572,0,0,8628,0,0,6614,0,0,66370,0,0,904,0,1,16510,0.0000605694,1,120948,0.00000826802
416358,"chr19:10335385:G>A","S1PR2","NM_004230:p.Ser66Leu","NM_004230:c.197C>T","EXON2","Unknown significance",,,"rs369436343",,,,"This variant is a VUS because it does not have enough information.",,0.998,"C",,,"1.0","D",0.000001,"D",1,"D",,"5.09","C",0,8600,0,1,4406,0.000226963,1,13006,0.0000768876,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,10350,0.0000966184,1,11572,0.0000864155,0,8630,0,0,6614,0,1,66384,0.0000150639,0,904,0,4,16512,0.000242248,7,120966,0.0000578675
416359,"chr19:10335394:T>C","S1PR2","NM_004230:p.Lys63Arg","NM_004230:c.188A>G","EXON2","Unknown significance",,,"rs746222276",,,,"This variant is a VUS because it does not have enough information.",,1.011,"C",,,"0.467","P",0.00002,"D",0.999283,"D",,"4.07","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10358,0,0,11574,0,0,8632,0,0,6614,0,1,66452,0.0000150485,0,904,0,0,16512,0,1,121046,0.00000826132
416360,"chr19:10335403:C>T","S1PR2","NM_004230:p.Arg60Gln","NM_004230:c.179G>A","EXON2","Unknown significance",,,"rs3745268",,,,"This variant is a VUS because it does not have enough information.",,0.892,"N",,,"1.0","D",0.000001,"D",1,"D",,"5.09","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,2,1008,0.002,0,978,0,2,5008,0.000399361,0,10368,0,0,11574,0,23,8636,0.00266327,0,6614,0,5,66472,0.0000752196,0,904,0,0,16512,0,28,121080,0.000231252
416361,"chr19:10335404:G>A","S1PR2","NM_004230:p.Arg60Stop","NM_004230:c.178C>T","EXON2","Unknown significance",,,"rs776098609",,,,"This variant is a VUS because it does not have enough information.",,0.045,"N",,,,,0.000001,"D",1,"D",,"4.03","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10366,0,0,11574,0,0,8636,0,0,6614,0,2,66482,0.0000300833,0,904,0,0,16512,0,2,121088,0.0000165169
416362,"chr19:10335404:G>C","S1PR2","NM_004230:p.Arg60Gly","NM_004230:c.178C>G","EXON2","Unknown significance",,,"rs776098609",,,,"This variant is a VUS because it does not have enough information.",,0.045,"N",,,"1.0","D",0.000001,"D",0.999995,"D",,"4.03","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10366,0,0,11574,0,0,8636,0,0,6614,0,1,66482,0.0000150417,0,904,0,0,16512,0,1,121088,0.00000825846
416363,"chr19:10335411:C>T","S1PR2","NM_004230:p.Ala57Ala","NM_004230:c.171G>A","EXON2","Unknown significance",,,"rs764211253",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10372,0,0,11574,0,0,8640,0,0,6614,0,1,66510,0.0000150353,0,904,0,0,16512,0,1,121126,0.00000825587
416364,"chr19:10335412:G>T","S1PR2","NM_004230:p.Ala57Glu","NM_004230:c.170C>A","EXON2","Unknown significance",,,"rs776758449",,,,"This variant is a VUS because it does not have enough information.",,0.998,"C",,,"0.997","D",0.000026,"D",0.999999,"D",,"5.09","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10376,0,0,11574,0,0,8640,0,0,6614,0,1,66506,0.0000150362,0,904,0,0,16510,0,1,121124,0.000008256
416365,"chr19:10335420:C>G","S1PR2","NM_004230:p.Val54Val","NM_004230:c.162G>C","EXON2","Unknown significance",,,"rs761860830",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,10384,0.000096302,0,11574,0,0,8642,0,0,6614,0,0,66532,0,0,906,0,0,16512,0,1,121164,0.00000825328
416366,"chr19:10335429:G>A","S1PR2","NM_004230:p.Asn51Asn","NM_004230:c.153C>T","EXON2","Unknown significance",,,"rs111877927",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416367,"chr19:10335442:A>G","S1PR2","NM_004230:p.Ile47Thr","NM_004230:c.140T>C","EXON2","Unknown significance",,,"rs765465116",,,,"This variant is a VUS because it does not have enough information.",,1.14,"C",,,"0.91","P",0.000012,"D",0.999999,"D",,"4.01","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,10390,0.0000962464,1,11574,0.0000864006,0,8648,0,0,6614,0,1,66610,0.0000150128,0,908,0,0,16512,0,3,121256,0.000024741
416368,"chr19:10335446:C>T","S1PR2","NM_004230:p.Ala46Thr","NM_004230:c.136G>A","EXON2","Likely benign",,,"rs750656745",,,,"Pathogenicity is based on prediction data only. 2 out of 5 predictions were pathogenic.",,0.042,"N",,,"0.004","B",0.003625,"N",0.540846,"D",,"2.96","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10390,0,0,11574,0,0,8648,0,0,6614,0,2,66612,0.0000300246,0,908,0,0,16512,0,2,121258,0.0000164938
416369,"chr19:10335447:G>A","S1PR2","NM_004230:p.Cys45Cys","NM_004230:c.135C>T","EXON2","Unknown significance",,,"rs758137994",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,10392,0.0000962279,0,11574,0,0,8648,0,0,6614,0,0,66616,0,0,908,0,0,16512,0,1,121264,0.00000824647
416370,"chr19:10335461:C>T","S1PR2","NM_004230:p.Val41Ile","NM_004230:c.121G>A","EXON2","Likely benign",,,"rs766168572",,,,"Pathogenicity is based on prediction data only. 0 out of 5 predictions were pathogenic.",,0.086,"N",,,"0.0","B",0.161634,"N",0.947381,"N",,"-5.16","N",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10392,0,0,11576,0,0,8646,0,0,6614,0,1,66628,0.0000150087,0,908,0,0,16512,0,1,121276,0.00000824565
416371,"chr19:10335462:G>A","S1PR2","NM_004230:p.Ile40Ile","NM_004230:c.120C>T","EXON2","Unknown significance",,,"rs145014162",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,1,8600,0.000116279,0,4406,0,1,13006,0.0000768876,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10392,0,0,11576,0,1,8644,0.000115687,0,6614,0,1,66626,0.0000150092,0,908,0,0,16512,0,2,121272,0.0000164919
416372,"chr19:10335464:T>C","S1PR2","NM_004230:p.Ile40Val","NM_004230:c.118A>G","EXON2","Unknown significance",,,"rs754899840",,,,"This variant is a VUS because it does not have enough information.",,1.011,"C",,,"0.688","P",0.00031,"D",0.694166,"D",,"5.09","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10392,0,0,11576,0,0,8646,0,0,6614,0,1,66630,0.0000150083,0,908,0,0,16512,0,1,121278,0.00000824552
416373,"chr19:10335469:G>C","S1PR2","NM_004230:p.Ala38Gly","NM_004230:c.113C>G","EXON2","Likely benign",,,"rs776432035",,,,"Pathogenicity is based on prediction data only. 0 out of 5 predictions were pathogenic.",,0.1,"N",,,"0.1","B",0.301008,"N",1,"N",,"-0.26","N",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416374,"chr19:10335471:C>T","S1PR2","NM_004230:p.Ser37Ser","NM_004230:c.111G>A","EXON2","Unknown significance",,,"rs781176630",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,10394,0.0000962094,0,11576,0,0,8646,0,0,6614,0,0,66626,0,0,908,0,3,16512,0.000181686,4,121276,0.0000329826
416375,"chr19:10335475:G>A","S1PR2","NM_004230:p.Ala36Val","NM_004230:c.107C>T","EXON2","Unknown significance",,,"rs747663144",,,,"This variant is a VUS because it does not have enough information.",,0.998,"C",,,"0.085","B",0.004871,"N",0.981645,"D",,"4.04","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10394,0,0,11574,0,0,8644,0,0,6614,0,3,66628,0.0000450261,0,908,0,0,16512,0,3,121274,0.0000247374
416376,"chr19:10335485:G>A","S1PR2","NM_004230:p.Arg33Cys","NM_004230:c.97C>T","EXON2","Unknown significance",,,"rs755629087",,,,"This variant is a VUS because it does not have enough information.",,0.998,"C",,,"1.0","D",0.001106,"N",1,"D",,"5.09","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10396,0,0,11574,0,0,8644,0,1,6614,0.000151194,0,66608,0,0,908,0,0,16512,0,1,121256,0.00000824701
416377,"chr19:10335486:G>T","S1PR2","NM_004230:p.Ser32Ser","NM_004230:c.96C>A","EXON2","Unknown significance",,,"rs777435510",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10396,0,0,11574,0,0,8644,0,0,6614,0,0,66610,0,0,908,0,1,16512,0.000060562,1,121258,0.00000824688
416378,"chr19:10335487:G>A","S1PR2","NM_004230:p.Ser32Phe","NM_004230:c.95C>T","EXON2","Unknown significance",,,"rs373332326",,,,"This variant is a VUS because it does not have enough information.",,0.998,"C",,,"0.991","D",0.05185,"N",0.999822,"D",,"5.09","C",1,8600,0.000116279,0,4406,0,1,13006,0.0000768876,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10396,0,0,11574,0,0,8644,0,0,6614,0,1,66598,0.0000150155,0,908,0,0,16512,0,1,121246,0.00000824769
416379,"chr19:10335489:G>A","S1PR2","NM_004230:p.Thr31Thr","NM_004230:c.93C>T","EXON2","Unknown significance",,,"rs772497544",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10396,0,0,11574,0,0,8644,0,0,6614,0,0,66602,0,0,908,0,1,16512,0.000060562,1,121250,0.00000824742
416380,"chr19:10335492:C>T","S1PR2","NM_004230:p.Thr30Thr","NM_004230:c.90G>A","EXON2","Unknown significance",,,"rs776010598",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,10390,0.0000962464,1,11572,0.0000864155,0,8638,0,0,6614,0,2,66596,0.0000300318,0,906,0,3,16512,0.000181686,7,121228,0.0000577424
416381,"chr19:10335501:C>T","S1PR2","NM_004230:p.Thr27Thr","NM_004230:c.81G>A","EXON2","Unknown significance",,,"rs747435736",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10390,0,0,11568,0,4,8638,0.00046307,0,6612,0,0,66568,0,0,906,0,0,16512,0,4,121194,0.0000330049
416382,"chr19:10335502:G>A","S1PR2","NM_004230:p.Thr27Met","NM_004230:c.80C>T","EXON2","Likely benign",,,"rs376767531",,,,"Pathogenicity is based on prediction data only. 1 out of 5 predictions were pathogenic.",,0.12,"N",,,"0.007","B",0.675138,"N",1,"N",,"0.49","C",1,8600,0.000116279,0,4406,0,1,13006,0.0000768876,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10390,0,0,11568,0,0,8638,0,0,6612,0,3,66570,0.0000450653,0,906,0,0,16512,0,3,121196,0.0000247533
416383,"chr19:10335510:C>T","S1PR2","NM_004230:p.Thr24Thr","NM_004230:c.72G>A","EXON2","Unknown significance",,,"rs777041753",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10378,0,0,11564,0,0,8628,0,0,6612,0,1,66530,0.0000150308,0,906,0,0,16512,0,1,121130,0.00000825559
416384,"chr19:10335511:G>A","S1PR2","NM_004230:p.Thr24Met","NM_004230:c.71C>T","EXON2","Likely benign",,,"rs189645503",,,,"Pathogenicity is based on prediction data only. 2 out of 5 predictions were pathogenic.",,0.998,"C",,,"0.004","B",0.008307,"N",0.669738,"N",,"1.8","C",2,8600,0.000232558,0,4406,0,2,13006,0.000153775,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,0,10374,0,1,11564,0.0000864753,0,8624,0,1,6612,0.00015124,21,66520,0.000315695,0,906,0,1,16512,0.000060562,24,121112,0.000198164
416385,"chr19:10335522:A>G","S1PR2","NM_004230:p.Tyr20Tyr","NM_004230:c.60T>C","EXON2","Unknown significance",,,"rs765252554",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10352,0,0,11552,0,1,8606,0.000116198,0,6610,0,2,66438,0.0000301033,0,906,0,0,16506,0,3,120970,0.0000247995
416386,"chr19:10335524:A>T","S1PR2","NM_004230:p.Tyr20Asn","NM_004230:c.58T>A","EXON2","Unknown significance",,,"rs556142679",,,,"This variant is a VUS because it does not have enough information.",,1.14,"C",,,"0.779","P",0.042044,"N",0.996236,"D",,"5.09","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416387,"chr19:10335525:A>G","S1PR2","NM_004230:p.Asn19Asn","NM_004230:c.57T>C","EXON2","Unknown significance",,,"rs773419520",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10350,0,0,11550,0,0,8600,0,0,6610,0,0,66414,0,0,906,0,1,16492,0.0000606355,1,120922,0.00000826979
416388,"chr19:10335536:C>G","S1PR2","NM_004230:p.Glu16Gln","NM_004230:c.46G>C","EXON2","Likely benign",,,"rs763178672",,,,"Pathogenicity is based on prediction data only. 1 out of 5 predictions were pathogenic.",,0.892,"N",,,"0.437","B",0.020586,"N",0.976582,"N",,"5.09","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10328,0,0,11534,0,0,8584,0,0,6608,0,2,66226,0.0000301996,0,904,0,0,16416,0,2,120600,0.0000165837
416389,"chr19:10335550:G>C","S1PR2","NM_004230:p.Pro11Arg","NM_004230:c.32C>G","EXON2","Likely benign",,,"rs766650153",,,,"Pathogenicity is based on prediction data only. 2 out of 5 predictions were pathogenic.",,0.998,"C",,,"0.047","B",0.045284,"N",0.999827,"N",,"3.98","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10290,0,1,11520,0.0000868056,0,8550,0,0,6602,0,0,65952,0,0,900,0,0,16092,0,1,119906,0.00000833987
416390,"chr19:10335552:G>T","S1PR2","NM_004230:p.Asn10Lys","NM_004230:c.30C>A","EXON2","Benign",,,"rs56357614",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,0.12,"N",,,"0.03","B",0.624577,"N",0.864671,"D",,"2.38","C",123,8600,0.0143023,14,4406,0.00317749,137,13006,0.0105336,,,,,,,,,,,,,,,,,,,,,,2,1322,0.0015,11,1006,0.0109,3,694,0.0043,0,1008,0,2,978,0.002,18,5008,0.00359425,24,10272,0.00233645,69,11516,0.00599166,5,8548,0.000584932,19,6602,0.00287792,947,65886,0.0143733,11,896,0.0122768,109,16006,0.00680995,1184,119726,0.00988925
416391,"chr19:10335564:C>T","S1PR2","NM_004230:p.Ser6Ser","NM_004230:c.18G>A","EXON2","Unknown significance",,,"rs754807977",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10184,0,0,11498,0,0,8502,0,0,6598,0,0,65388,0,0,886,0,1,15412,0.0000648845,1,118468,0.0000084411
416392,"chr19:10335565:G>A","S1PR2","NM_004230:p.Ser6Leu","NM_004230:c.17C>T","EXON2","Unknown significance",,,"rs767468819",,,,"This variant is a VUS because it does not have enough information.",,0.998,"C",,,"0.85","P",0.626007,"N",0.992623,"D",,"4.02","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,10184,0,0,11496,0,0,8502,0,0,6600,0,0,65382,0,0,884,0,1,15434,0.000064792,1,118482,0.0000084401
416393,"chr19:10335574:C>T","S1PR2","NM_004230:p.Ser3Asn","NM_004230:c.8G>A","EXON2","Unknown significance",,,"rs181702636",,,,"This variant is a VUS because it does not have enough information.",,0.036,"N",,,"0.001","B",0.001541,"U",0.817189,"D",,"0.346","C",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416394,"chr19:10335581:T>C","S1PR2","NM_004230:p.Met1Val","NM_004230:c.1A>G","EXON2","Unknown significance",,,"rs370619769",,,,"This variant is a VUS because it does not have enough information.",,1.011,"C",,,"0.956","P",0.070849,"U",1,"D",,"5.09","C",1,8600,0.000116279,0,4406,0,1,13006,0.0000768876,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416395,"chr19:10335582:->GGTG","S1PR2",,"NM_004230:c.-1_1insCACC","FIVE_PRIME_EXON","Unknown significance",,,"rs779868016",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416396,"chr19:10335582:G>T","S1PR2",,"NM_004230:c.-1C>A","FIVE_PRIME_EXON","Unknown significance",,,"rs755288880",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416397,"chr19:10335585:->G","S1PR2",,"NM_004230:c.-4_-3insC","FIVE_PRIME_EXON","Unknown significance",,,"rs35452612",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416398,"chr19:10335597:C>T","S1PR2",,"NM_004230:c.-16G>A","FIVE_PRIME_EXON","Unknown significance",,,"rs752600028",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9926,0,0,11416,0,0,8364,0,0,6572,0,1,63992,0.000015627,0,844,0,0,13666,0,1,114780,0.00000871232
416399,"chr19:10335605:G>C","S1PR2",,"NM_004230:c.-24C>G","FIVE_PRIME_EXON","Unknown significance",,,"rs755612253",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9850,0,1,11382,0.000087858,0,8312,0,0,6568,0,0,63610,0,0,836,0,0,13116,0,1,113674,0.00000879709
416400,"chr19:10335611:G>-","S1PR2",,"NM_004230:c.-30delC","FIVE_PRIME_EXON","Unknown significance",,,"rs753386724",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,9794,0.000102103,0,11378,0,0,8282,0,0,6568,0,3,63334,0.0000473679,0,828,0,0,12770,0,4,112954,0.0000354126
416401,"chr19:10335611:G>A","S1PR2",,"NM_004230:c.-30C>T","FIVE_PRIME_EXON","Unknown significance",,,"rs777150484",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9778,0,0,11366,0,0,8270,0,0,6564,0,2,63242,0.0000316246,0,822,0,0,12592,0,2,112634,0.0000177566
416402,"chr19:10335614:G>A","S1PR2",,"NM_004230:c.-33C>T","FIVE_PRIME_EXON","Unknown significance",,,"rs753471077",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9748,0,0,11344,0,0,8234,0,0,6562,0,1,63108,0.0000158459,0,824,0,0,12478,0,1,112298,0.00000890488
416403,"chr19:10335631:G>C","S1PR2",,"NM_004230:c.-42-8C>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs756955645",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416404,"chr19:10335633:->AGAC","S1PR2",,"NM_004230:c.-42-10_-42-9insGTCT","FIVE_PRIME_INTRON","Unknown significance",,,"rs778620269",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9238,0,1,10718,0.000093301,0,7752,0,0,6408,0,3,59632,0.0000503086,0,778,0,0,10518,0,4,105044,0.0000380793
416405,"chr19:10335633:->AGACAGAC","S1PR2",,"NM_004230:c.-42-10_-42-9insGTCTGTCT","FIVE_PRIME_INTRON","Unknown significance",,,"rs778620269",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,9238,0,0,10718,0,0,7752,0,0,6408,0,1,59632,0.0000167695,0,778,0,0,10518,0,1,105044,0.00000951982
416406,"chr19:10335633:AGAC>-","S1PR2",,"NM_004230:c.-42-10_-42-5delGTCT","FIVE_PRIME_INTRON","Unknown significance",,,"rs754625300",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,7,9238,0.00075774,16,10718,0.00149282,6,7752,0.000773994,3,6408,0.000468165,65,59632,0.00109002,2,778,0.00257069,14,10518,0.00133105,113,105044,0.00107574
416407,"chr19:10335655:T>C","S1PR2",,"NM_004230:c.-42-32A>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs769701372",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416408,"chr19:10335666:T>A","S1PR2",,"NM_004230:c.-42-43A>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs772997253",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416409,"chr19:10335693:G>A","S1PR2",,"NM_004230:c.-42-70C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs150452226",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2,1322,0.0015,0,1006,0,0,694,0,0,1008,0,0,978,0,2,5008,0.000399361,,,,,,,,,,,,,,,,,,,,,,,,
416410,"chr19:10335700:C>T","S1PR2",,"NM_004230:c.-42-77G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs541277550",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416411,"chr19:10335732:G>T","S1PR2",,"NM_004230:c.-42-109C>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs762914426",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416412,"chr19:10335779:A>G","S1PR2",,"NM_004230:c.-42-156T>C","FIVE_PRIME_INTRON","Benign",,,"rs114756388",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,20,1322,0.0151,0,1006,0,0,694,0,0,1008,0,0,978,0,20,5008,0.00399361,,,,,,,,,,,,,,,,,,,,,,,,
416413,"chr19:10335780:C>T","S1PR2",,"NM_004230:c.-42-157G>A","FIVE_PRIME_INTRON","Benign",,,"rs11878516",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,224,1322,0.1694,186,1006,0.1849,114,694,0.1643,83,1008,0.0823,106,978,0.1084,713,5008,0.142372,,,,,,,,,,,,,,,,,,,,,,,,
416414,"chr19:10335792:A>G","S1PR2",,"NM_004230:c.-42-169T>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs542424487",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,3,1322,0.0023,0,1006,0,0,694,0,0,1008,0,0,978,0,3,5008,0.000599042,,,,,,,,,,,,,,,,,,,,,,,,
416415,"chr19:10335819:C>G","S1PR2",,"NM_004230:c.-42-196G>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs138286594",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416416,"chr19:10335832:C>T","S1PR2",,"NM_004230:c.-42-209G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs531855062",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416417,"chr19:10335833:G>A","S1PR2",,"NM_004230:c.-42-210C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs796134604",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416418,"chr19:10335836:A>G","S1PR2",,"NM_004230:c.-42-213T>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs550036028",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416419,"chr19:10335858:C>T","S1PR2",,"NM_004230:c.-42-235G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs142736246",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416420,"chr19:10335861:C>A","S1PR2",,"NM_004230:c.-42-238G>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs571699445",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,1,978,0.001,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416421,"chr19:10335881:C>T","S1PR2",,"NM_004230:c.-42-258G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs532590835",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416422,"chr19:10335907:C>A","S1PR2",,"NM_004230:c.-42-284G>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs547808453",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,1,978,0.001,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416423,"chr19:10335911:A>G","S1PR2",,"NM_004230:c.-42-288T>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs146961283",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416424,"chr19:10335923:A>G","S1PR2",,"NM_004230:c.-42-300T>C","FIVE_PRIME_INTRON","Benign",,,"rs74179903",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,5,1322,0.0038,66,1006,0.0656,137,694,0.1974,0,1008,0,12,978,0.0123,220,5008,0.0439297,,,,,,,,,,,,,,,,,,,,,,,,
416425,"chr19:10335959:C>T","S1PR2",,"NM_004230:c.-42-336G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs186110525",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416426,"chr19:10335976:G>A","S1PR2",,"NM_004230:c.-42-353C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs570119315",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416427,"chr19:10335989:C>T","S1PR2",,"NM_004230:c.-42-366G>A","FIVE_PRIME_INTRON","Benign",,,"rs376986652",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,10,1008,0.0099,0,978,0,10,5008,0.00199681,,,,,,,,,,,,,,,,,,,,,,,,
416428,"chr19:10336067:->T","S1PR2",,"NM_004230:c.-42-444_-42-443insA","FIVE_PRIME_INTRON","Unknown significance",,,"rs35464657",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416429,"chr19:10336067:->TT","S1PR2",,"NM_004230:c.-42-444_-42-443insAA","FIVE_PRIME_INTRON","Unknown significance",,,"rs35464657",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416430,"chr19:10336067:->TTT","S1PR2",,"NM_004230:c.-42-444_-42-443insAAA","FIVE_PRIME_INTRON","Unknown significance",,,"rs35464657",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416431,"chr19:10336067:T>-","S1PR2",,"NM_004230:c.-42-444delA","FIVE_PRIME_INTRON","Unknown significance",,,"rs35814702",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416432,"chr19:10336067:TTT>-","S1PR2",,"NM_004230:c.-42-444_-42-440delAAA","FIVE_PRIME_INTRON","Unknown significance",,,"rs545766744",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416433,"chr19:10336115:A>C","S1PR2",,"NM_004230:c.-42-492T>G","FIVE_PRIME_INTRON","Benign",,,"rs8102623",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1201,1322,0.9085,818,1006,0.8131,560,694,0.8069,549,1008,0.5446,783,978,0.8006,3911,5008,0.78095,,,,,,,,,,,,,,,,,,,,,,,,
416434,"chr19:10336135:C>T","S1PR2",,"NM_004230:c.-42-512G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs534124028",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416435,"chr19:10336175:T>C","S1PR2",,"NM_004230:c.-42-552A>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs11671328",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416436,"chr19:10336193:T>C","S1PR2",,"NM_004230:c.-42-570A>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs11671332",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416437,"chr19:10336249:T>A","S1PR2",,"NM_004230:c.-42-626A>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs78329317",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416438,"chr19:10336267:G>C","S1PR2",,"NM_004230:c.-42-644C>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs781059550",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416439,"chr19:10336325:C>T","S1PR2",,"NM_004230:c.-42-702G>A","FIVE_PRIME_INTRON","Benign",,,"rs143418139",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,20,1322,0.0151,0,1006,0,0,694,0,0,1008,0,0,978,0,20,5008,0.00399361,,,,,,,,,,,,,,,,,,,,,,,,
416440,"chr19:10336339:G>A","S1PR2",,"NM_004230:c.-42-716C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs745857039",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416441,"chr19:10336363:C>T","S1PR2",,"NM_004230:c.-42-740G>A","FIVE_PRIME_INTRON","Benign",,,"rs143905261",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,14,1322,0.0106,0,1006,0,0,694,0,0,1008,0,0,978,0,14,5008,0.00279553,,,,,,,,,,,,,,,,,,,,,,,,
416442,"chr19:10336374:G>A","S1PR2",,"NM_004230:c.-42-751C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs780494179",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416443,"chr19:10336395:T>A","S1PR2",,"NM_004230:c.-42-772A>T","FIVE_PRIME_INTRON","Benign",,,"rs114116676",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,75,1322,0.0567,0,1006,0,2,694,0.0029,0,1008,0,0,978,0,77,5008,0.0153754,,,,,,,,,,,,,,,,,,,,,,,,
416444,"chr19:10336415:G>A","S1PR2",,"NM_004230:c.-42-792C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs769287892",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416445,"chr19:10336524:A>G","S1PR2",,"NM_004230:c.-42-901T>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs572026981",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416446,"chr19:10336542:T>G","S1PR2",,"NM_004230:c.-42-919A>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs775037760",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416447,"chr19:10336575:A>G","S1PR2",,"NM_004230:c.-42-952T>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs542529862",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,3,1008,0.003,0,978,0,3,5008,0.000599042,,,,,,,,,,,,,,,,,,,,,,,,
416448,"chr19:10336605:T>C","S1PR2",,"NM_004230:c.-42-982A>G","FIVE_PRIME_INTRON","Benign",,,"rs190880148",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,16,1322,0.0121,0,1006,0,0,694,0,0,1008,0,0,978,0,16,5008,0.00319489,,,,,,,,,,,,,,,,,,,,,,,,
416449,"chr19:10336628:C>T","S1PR2",,"NM_004230:c.-42-1005G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs531440117",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416450,"chr19:10336656:G>T","S1PR2",,"NM_004230:c.-42-1033C>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs199814671",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416451,"chr19:10336663:->CC","S1PR2",,"NM_004230:c.-42-1040_-42-1039insGG","FIVE_PRIME_INTRON","Benign",,,"rs57295053",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,68,1322,0.0514,0,1006,0,4,694,0.0058,0,1008,0,0,978,0,72,5008,0.014377,,,,,,,,,,,,,,,,,,,,,,,,
416452,"chr19:10336681:C>T","S1PR2",,"NM_004230:c.-42-1058G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs370371926",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416453,"chr19:10336722:G>-","S1PR2",,"NM_004230:c.-42-1099delC","FIVE_PRIME_INTRON","Benign",,,"rs34638919",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,114,1322,0.0862,406,1006,0.4036,181,694,0.2608,155,1008,0.1538,407,978,0.4162,1263,5008,0.252196,,,,,,,,,,,,,,,,,,,,,,,,
416454,"chr19:10336722:->G","S1PR2",,"NM_004230:c.-42-1099_-42-1098insC","FIVE_PRIME_INTRON","Unknown significance",,,"rs761898469",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416455,"chr19:10336722:G>C","S1PR2",,"NM_004230:c.-42-1099C>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs113808592",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416456,"chr19:10336722:G>T","S1PR2",,"NM_004230:c.-42-1099C>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs113808592",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416457,"chr19:10336728:C>T","S1PR2",,"NM_004230:c.-42-1105G>A","FIVE_PRIME_INTRON","Benign",,,"rs76850638",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,375,1322,0.2837,0,1006,0,13,694,0.0187,0,1008,0,0,978,0,388,5008,0.077476,,,,,,,,,,,,,,,,,,,,,,,,
416458,"chr19:10336740:C>G","S1PR2",,"NM_004230:c.-42-1117G>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs373821386",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416459,"chr19:10336780:G>A","S1PR2",,"NM_004230:c.-42-1157C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs565425145",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,2,694,0.0029,0,1008,0,0,978,0,2,5008,0.000399361,,,,,,,,,,,,,,,,,,,,,,,,
416460,"chr19:10336791:C>T","S1PR2",,"NM_004230:c.-42-1168G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs376962268",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416461,"chr19:10336792:G>A","S1PR2",,"NM_004230:c.-42-1169C>T","FIVE_PRIME_INTRON","Benign",,,"rs548423011",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,9,978,0.0092,9,5008,0.00179712,,,,,,,,,,,,,,,,,,,,,,,,
416462,"chr19:10336797:C>A","S1PR2",,"NM_004230:c.-42-1174G>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs370768731",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416463,"chr19:10336822:->GAGA","S1PR2",,"NM_004230:c.-42-1199_-42-1198insTCTC","FIVE_PRIME_INTRON","Unknown significance",,,"rs779730945",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416464,"chr19:10336866:C>A","S1PR2",,"NM_004230:c.-42-1243G>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs538052839",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416465,"chr19:10336876:C>T","S1PR2",,"NM_004230:c.-42-1253G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs768287206",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416466,"chr19:10336877:G>A","S1PR2",,"NM_004230:c.-42-1254C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs566044122",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,1,978,0.001,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416467,"chr19:10336912:C>T","S1PR2",,"NM_004230:c.-42-1289G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs530437233",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416468,"chr19:10336913:G>A","S1PR2",,"NM_004230:c.-42-1290C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs773903217",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416469,"chr19:10336921:C>G","S1PR2",,"NM_004230:c.-42-1298G>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs75733536",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,2,1006,0.002,0,694,0,0,1008,0,2,978,0.002,4,5008,0.000798722,,,,,,,,,,,,,,,,,,,,,,,,
416470,"chr19:10336927:T>C","S1PR2",,"NM_004230:c.-42-1304A>G","FIVE_PRIME_INTRON","Benign",,,"rs570311109",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,7,978,0.0072,7,5008,0.00139776,,,,,,,,,,,,,,,,,,,,,,,,
416471,"chr19:10336951:C>T","S1PR2",,"NM_004230:c.-42-1328G>A","FIVE_PRIME_INTRON","Benign",,,"rs116357424",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,100,1322,0.0756,0,1006,0,5,694,0.0072,0,1008,0,1,978,0.001,106,5008,0.0211661,,,,,,,,,,,,,,,,,,,,,,,,
416472,"chr19:10336952:G>A","S1PR2",,"NM_004230:c.-42-1329C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs552693689",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416473,"chr19:10336974:AG>-","S1PR2",,"NM_004230:c.-42-1351_-42-1348delCT","FIVE_PRIME_INTRON","Unknown significance",,,"rs754587818",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416474,"chr19:10337022:T>G","S1PR2",,"NM_004230:c.-42-1399A>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs750926790",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416475,"chr19:10337033:T>G","S1PR2",,"NM_004230:c.-42-1410A>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs571020992",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,1,978,0.001,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416476,"chr19:10337060:C>T","S1PR2",,"NM_004230:c.-42-1437G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs183545249",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,4,1322,0.003,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,5,5008,0.000998403,,,,,,,,,,,,,,,,,,,,,,,,
416477,"chr19:10337063:G>C","S1PR2",,"NM_004230:c.-42-1440C>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs148269931",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416478,"chr19:10337131:T>A","S1PR2",,"NM_004230:c.-42-1508A>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs375326682",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416479,"chr19:10337135:A>-","S1PR2",,"NM_004230:c.-42-1512delT","FIVE_PRIME_INTRON","Unknown significance",,,"rs757871042",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416480,"chr19:10337135:A>G","S1PR2",,"NM_004230:c.-42-1512T>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs74179904",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416481,"chr19:10337145:T>C","S1PR2",,"NM_004230:c.-42-1522A>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs185311251",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,4,1008,0.004,1,978,0.001,5,5008,0.000998403,,,,,,,,,,,,,,,,,,,,,,,,
416482,"chr19:10337152:C>T","S1PR2",,"NM_004230:c.-42-1529G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs118140245",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416483,"chr19:10337153:G>A","S1PR2",,"NM_004230:c.-42-1530C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs761333910",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416484,"chr19:10337161:->C","S1PR2",,"NM_004230:c.-42-1538_-42-1537insG","FIVE_PRIME_INTRON","Unknown significance",,,"rs774821140",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416485,"chr19:10337217:T>C","S1PR2",,"NM_004230:c.-42-1594A>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs554608588",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,3,978,0.0031,3,5008,0.000599042,,,,,,,,,,,,,,,,,,,,,,,,
416486,"chr19:10337230:C>T","S1PR2",,"NM_004230:c.-42-1607G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs576283555",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2,1322,0.0015,0,1006,0,0,694,0,0,1008,0,0,978,0,2,5008,0.000399361,,,,,,,,,,,,,,,,,,,,,,,,
416487,"chr19:10337246:G>A","S1PR2",,"NM_004230:c.-42-1623C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs745961342",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416488,"chr19:10337321:G>A","S1PR2",,"NM_004230:c.-42-1698C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs543255561",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416489,"chr19:10337329:C>T","S1PR2",,"NM_004230:c.-42-1706G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs372420876",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,3,1008,0.003,1,978,0.001,4,5008,0.000798722,,,,,,,,,,,,,,,,,,,,,,,,
416490,"chr19:10337432:G>A","S1PR2",,"NM_004230:c.-42-1809C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs577429116",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416491,"chr19:10337450:T>G","S1PR2",,"NM_004230:c.-42-1827A>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs541508099",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416492,"chr19:10337509:G>A","S1PR2",,"NM_004230:c.-42-1886C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs559860451",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,2,1008,0.002,0,978,0,2,5008,0.000399361,,,,,,,,,,,,,,,,,,,,,,,,
416493,"chr19:10337527:T>C","S1PR2",,"NM_004230:c.-42-1904A>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs753901268",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416494,"chr19:10337582:A>G","S1PR2",,"NM_004230:c.-42-1959T>C","FIVE_PRIME_INTRON","Benign",,,"rs114474550",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,75,1322,0.0567,0,1006,0,2,694,0.0029,0,1008,0,0,978,0,77,5008,0.0153754,,,,,,,,,,,,,,,,,,,,,,,,
416495,"chr19:10337598:->C","S1PR2",,"NM_004230:c.-42-1975_-42-1974insG","FIVE_PRIME_INTRON","Benign",,,"rs576972961",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,155,1322,0.1172,217,1006,0.2157,242,694,0.3487,231,1008,0.2292,245,978,0.2505,1090,5008,0.217652,,,,,,,,,,,,,,,,,,,,,,,,
416496,"chr19:10337598:C>-","S1PR2",,"NM_004230:c.-42-1975delG","FIVE_PRIME_INTRON","Benign",,,"rs542709020",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,91,1322,0.0688,0,1006,0,5,694,0.0072,0,1008,0,0,978,0,96,5008,0.0191693,,,,,,,,,,,,,,,,,,,,,,,,
416497,"chr19:10337605:A>C","S1PR2",,"NM_004230:c.-42-1982T>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs758630488",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416498,"chr19:10337607:C>A","S1PR2",,"NM_004230:c.-42-1984G>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs780139612",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416499,"chr19:10337608:C>T","S1PR2",,"NM_004230:c.-42-1985G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs548563435",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,3,1322,0.0023,0,1006,0,0,694,0,0,1008,0,0,978,0,3,5008,0.000599042,,,,,,,,,,,,,,,,,,,,,,,,
416500,"chr19:10337699:G>A","S1PR2",,"NM_004230:c.-42-2076C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs755021957",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416501,"chr19:10337771:G>T","S1PR2",,"NM_004230:c.-42-2148C>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs779157306",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416502,"chr19:10337776:G>C","S1PR2",,"NM_004230:c.-42-2153C>G","FIVE_PRIME_INTRON","Benign",,,"rs80161551",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,45,1322,0.034,4,1006,0.004,2,694,0.0029,72,1008,0.0714,13,978,0.0133,136,5008,0.0271565,,,,,,,,,,,,,,,,,,,,,,,,
416503,"chr19:10337779:G>A","S1PR2",,"NM_004230:c.-42-2156C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs189970301",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416504,"chr19:10337782:G>A","S1PR2",,"NM_004230:c.-42-2159C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs552513320",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416505,"chr19:10337808:T>A","S1PR2",,"NM_004230:c.-42-2185A>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs182623858",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,1,1006,0.001,0,694,0,0,1008,0,1,978,0.001,3,5008,0.000599042,,,,,,,,,,,,,,,,,,,,,,,,
416506,"chr19:10337868:G>C","S1PR2",,"NM_004230:c.-42-2245C>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs534868265",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416507,"chr19:10337877:T>C","S1PR2",,"NM_004230:c.-42-2254A>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs745789870",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416508,"chr19:10337897:T>A","S1PR2",,"NM_004230:c.-42-2274A>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs568563911",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,4,978,0.0041,4,5008,0.000798722,,,,,,,,,,,,,,,,,,,,,,,,
416509,"chr19:10337907:->AG","S1PR2",,"NM_004230:c.-42-2284_-42-2283insCT","FIVE_PRIME_INTRON","Benign",,,"rs112587180",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,56,1322,0.0424,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,57,5008,0.0113818,,,,,,,,,,,,,,,,,,,,,,,,
416510,"chr19:10337909:C>T","S1PR2",,"NM_004230:c.-42-2286G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs769660904",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416511,"chr19:10337910:G>A","S1PR2",,"NM_004230:c.-42-2287C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs779860465",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416512,"chr19:10337941:A>G","S1PR2",,"NM_004230:c.-42-2318T>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs565428079",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,4,1008,0.004,0,978,0,4,5008,0.000798722,,,,,,,,,,,,,,,,,,,,,,,,
416513,"chr19:10337957:A>G","S1PR2",,"NM_004230:c.-42-2334T>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs111445537",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416514,"chr19:10338060:G>A","S1PR2",,"NM_004230:c.-42-2437C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs768069008",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416515,"chr19:10338069:T>A","S1PR2",,"NM_004230:c.-42-2446A>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs774029594",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416516,"chr19:10338099:T>-","S1PR2",,"NM_004230:c.-42-2476delA","FIVE_PRIME_INTRON","Unknown significance",,,"rs776979639",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416517,"chr19:10338104:G>C","S1PR2",,"NM_004230:c.-42-2481C>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs761409120",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416518,"chr19:10338126:G>A","S1PR2",,"NM_004230:c.-42-2503C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs772563067",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416519,"chr19:10338131:C>T","S1PR2",,"NM_004230:c.-42-2508G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs535914436",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416520,"chr19:10338177:C>-","S1PR2",,"NM_004230:c.-42-2554delG","FIVE_PRIME_INTRON","Unknown significance",,,"rs773087842",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416521,"chr19:10338192:G>-","S1PR2",,"NM_004230:c.-42-2569delC","FIVE_PRIME_INTRON","Unknown significance",,,"rs765172135",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416522,"chr19:10338211:C>T","S1PR2",,"NM_004230:c.-42-2588G>A","FIVE_PRIME_INTRON","Benign",,,"rs75972477",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,25,1322,0.0189,0,1006,0,0,694,0,0,1008,0,0,978,0,25,5008,0.00499201,,,,,,,,,,,,,,,,,,,,,,,,
416523,"chr19:10338219:C>T","S1PR2",,"NM_004230:c.-42-2596G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs534846763",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416524,"chr19:10338235:A>C","S1PR2",,"NM_004230:c.-42-2612T>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs576266757",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,2,5008,0.000399361,,,,,,,,,,,,,,,,,,,,,,,,
416525,"chr19:10338258:G>A","S1PR2",,"NM_004230:c.-42-2635C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs537315924",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416526,"chr19:10338307:G>A","S1PR2",,"NM_004230:c.-42-2684C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs761135588",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416527,"chr19:10338344:T>C","S1PR2",,"NM_004230:c.-42-2721A>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs558807902",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416528,"chr19:10338351:C>T","S1PR2",,"NM_004230:c.-42-2728G>A","FIVE_PRIME_INTRON","Benign",,,"rs7246367",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2,1322,0.0015,43,1006,0.0427,11,694,0.0159,1,1008,0.001,5,978,0.0051,62,5008,0.0123802,,,,,,,,,,,,,,,,,,,,,,,,
416529,"chr19:10338353:G>A","S1PR2",,"NM_004230:c.-42-2730C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs188139894",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416530,"chr19:10338400:C>T","S1PR2",,"NM_004230:c.-42-2777G>A","FIVE_PRIME_INTRON","Benign",,,"rs141378756",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,7,694,0.0101,7,1008,0.0069,1,978,0.001,15,5008,0.00299521,,,,,,,,,,,,,,,,,,,,,,,,
416531,"chr19:10338413:C>G","S1PR2",,"NM_004230:c.-42-2790G>C","FIVE_PRIME_INTRON","Benign",,,"rs62128726",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,113,1322,0.0855,406,1006,0.4036,181,694,0.2608,155,1008,0.1538,409,978,0.4182,1264,5008,0.252396,,,,,,,,,,,,,,,,,,,,,,,,
416532,"chr19:10338413:C>A","S1PR2",,"NM_004230:c.-42-2790G>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs62128726",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416533,"chr19:10338419:G>T","S1PR2",,"NM_004230:c.-42-2796C>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs541870861",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,3,694,0.0043,0,1008,0,0,978,0,3,5008,0.000599042,,,,,,,,,,,,,,,,,,,,,,,,
416534,"chr19:10338428:T>C","S1PR2",,"NM_004230:c.-42-2805A>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs765285419",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416535,"chr19:10338433:G>A","S1PR2",,"NM_004230:c.-42-2810C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs367824087",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416536,"chr19:10338473:G>A","S1PR2",,"NM_004230:c.-42-2850C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs758675119",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416537,"chr19:10338475:->G","S1PR2",,"NM_004230:c.-42-2852_-42-2851insC","FIVE_PRIME_INTRON","Unknown significance",,,"rs35493488",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416538,"chr19:10338488:G>T","S1PR2",,"NM_004230:c.-42-2865C>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs563667391",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416539,"chr19:10338501:G>A","S1PR2",,"NM_004230:c.-42-2878C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs531133425",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,2,978,0.002,2,5008,0.000399361,,,,,,,,,,,,,,,,,,,,,,,,
416540,"chr19:10338522:C>G","S1PR2",,"NM_004230:c.-42-2899G>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs764310890",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416541,"chr19:10338544:G>C","S1PR2",,"NM_004230:c.-42-2921C>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs750147746",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416542,"chr19:10338544:G>T","S1PR2",,"NM_004230:c.-42-2921C>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs750147746",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416543,"chr19:10338554:G>C","S1PR2",,"NM_004230:c.-42-2931C>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs371303430",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416544,"chr19:10338575:A>-","S1PR2",,"NM_004230:c.-42-2952delT","FIVE_PRIME_INTRON","Unknown significance",,,"rs763013703",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416545,"chr19:10338614:A>T","S1PR2",,"NM_004230:c.-42-2991T>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs546118741",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416546,"chr19:10338632:G>A","S1PR2",,"NM_004230:c.-42-3009C>T","FIVE_PRIME_INTRON","Benign",,,"rs114313250",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,74,1322,0.056,0,1006,0,2,694,0.0029,0,1008,0,0,978,0,76,5008,0.0151757,,,,,,,,,,,,,,,,,,,,,,,,
416547,"chr19:10338671:C>T","S1PR2",,"NM_004230:c.-42-3048G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs528702811",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,1,978,0.001,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416548,"chr19:10338674:G>A","S1PR2",,"NM_004230:c.-42-3051C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs546788196",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,3,1006,0.003,0,694,0,0,1008,0,0,978,0,3,5008,0.000599042,,,,,,,,,,,,,,,,,,,,,,,,
416549,"chr19:10338676:T>G","S1PR2",,"NM_004230:c.-42-3053A>C","FIVE_PRIME_INTRON","Benign",,,"rs8104426",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1145,1322,0.8661,820,1006,0.8151,561,694,0.8084,547,1008,0.5427,786,978,0.8037,3859,5008,0.770567,,,,,,,,,,,,,,,,,,,,,,,,
416550,"chr19:10338702:C>T","S1PR2",,"NM_004230:c.-42-3079G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs529755452",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416551,"chr19:10338764:A>G","S1PR2",,"NM_004230:c.-43+3116T>C","FIVE_PRIME_INTRON","Benign",,,"rs4804496",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1146,1322,0.8669,818,1006,0.8131,559,694,0.8055,547,1008,0.5427,785,978,0.8027,3855,5008,0.769768,,,,,,,,,,,,,,,,,,,,,,,,
416552,"chr19:10338798:A>C","S1PR2",,"NM_004230:c.-43+3082T>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs569604451",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416553,"chr19:10338811:A>G","S1PR2",,"NM_004230:c.-43+3069T>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs754478691",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416554,"chr19:10338812:CT>-","S1PR2",,"NM_004230:c.-43+3068_-43+3071delAG","FIVE_PRIME_INTRON","Unknown significance",,,"rs370290730",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416555,"chr19:10338815:A>-","S1PR2",,"NM_004230:c.-43+3065delT","FIVE_PRIME_INTRON","Unknown significance",,,"rs775273252",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416556,"chr19:10338815:AA>-","S1PR2",,"NM_004230:c.-43+3065_-43+3068delTT","FIVE_PRIME_INTRON","Unknown significance",,,"rs141807915",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416557,"chr19:10338819:A>C","S1PR2",,"NM_004230:c.-43+3061T>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs75375925",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416558,"chr19:10338838:A>T","S1PR2",,"NM_004230:c.-43+3042T>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs74401753",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416559,"chr19:10338840:T>A","S1PR2",,"NM_004230:c.-43+3040A>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs75326915",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416560,"chr19:10338856:T>G","S1PR2",,"NM_004230:c.-43+3024A>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs139115005",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416561,"chr19:10338860:C>T","S1PR2",,"NM_004230:c.-43+3020G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs536618604",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416562,"chr19:10338861:G>A","S1PR2",,"NM_004230:c.-43+3019C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs558925417",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416563,"chr19:10338902:C>G","S1PR2",,"NM_004230:c.-43+2978G>C","FIVE_PRIME_INTRON","Benign",,,"rs144252086",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,205,1322,0.1551,1,1006,0.001,4,694,0.0058,0,1008,0,0,978,0,210,5008,0.0419329,,,,,,,,,,,,,,,,,,,,,,,,
416564,"chr19:10338906:T>C","S1PR2",,"NM_004230:c.-43+2974A>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs767113061",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416565,"chr19:10338911:C>T","S1PR2",,"NM_004230:c.-43+2969G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs577086876",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416566,"chr19:10338912:C>T","S1PR2",,"NM_004230:c.-43+2968G>A","FIVE_PRIME_INTRON","Benign",,,"rs146093510",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,37,1322,0.028,0,1006,0,0,694,0,0,1008,0,0,978,0,37,5008,0.00738818,,,,,,,,,,,,,,,,,,,,,,,,
416567,"chr19:10338942:C>T","S1PR2",,"NM_004230:c.-43+2938G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs368884009",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416568,"chr19:10338946:G>C","S1PR2",,"NM_004230:c.-43+2934C>G","FIVE_PRIME_INTRON","Benign",,,"rs192708664",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,68,1322,0.0514,0,1006,0,4,694,0.0058,0,1008,0,0,978,0,72,5008,0.014377,,,,,,,,,,,,,,,,,,,,,,,,
416569,"chr19:10338946:GC>CT","S1PR2",,,,"Unknown significance",,,"rs386806765",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416570,"chr19:10338947:C>T","S1PR2",,"NM_004230:c.-43+2933G>A","FIVE_PRIME_INTRON","Benign",,,"rs183489172",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,68,1322,0.0514,0,1006,0,4,694,0.0058,0,1008,0,0,978,0,72,5008,0.014377,,,,,,,,,,,,,,,,,,,,,,,,
416571,"chr19:10338986:CAAAACAAAA>-","S1PR2",,"NM_004230:c.-43+2894_-43+2905delTTTTGTTTTG","FIVE_PRIME_INTRON","Benign",,,"rs140658666",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,104,1322,0.0787,184,1006,0.1829,110,694,0.1585,85,1008,0.0843,107,978,0.1094,590,5008,0.117812,,,,,,,,,,,,,,,,,,,,,,,,
416572,"chr19:10338986:CAAAA>-","S1PR2",,"NM_004230:c.-43+2894_-43+2900delTTTTG","FIVE_PRIME_INTRON","Unknown significance",,,"rs754423340",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416573,"chr19:10339016:T>C","S1PR2",,"NM_004230:c.-43+2864A>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs557155321",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2,1322,0.0015,0,1006,0,0,694,0,0,1008,0,0,978,0,2,5008,0.000399361,,,,,,,,,,,,,,,,,,,,,,,,
416574,"chr19:10339020:A>G","S1PR2",,"NM_004230:c.-43+2860T>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs747790901",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416575,"chr19:10339055:G>A","S1PR2",,"NM_004230:c.-43+2825C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs374606533",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416576,"chr19:10339070:C>T","S1PR2",,"NM_004230:c.-43+2810G>A","FIVE_PRIME_INTRON","Benign",,,"rs187508726",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,10,1006,0.0099,3,694,0.0043,0,1008,0,0,978,0,13,5008,0.00259585,,,,,,,,,,,,,,,,,,,,,,,,
416577,"chr19:10339099:T>G","S1PR2",,"NM_004230:c.-43+2781A>C","FIVE_PRIME_INTRON","Benign",,,"rs140102339",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,45,1322,0.034,0,1006,0,2,694,0.0029,0,1008,0,0,978,0,47,5008,0.00938498,,,,,,,,,,,,,,,,,,,,,,,,
416578,"chr19:10339116:C>T","S1PR2",,"NM_004230:c.-43+2764G>A","FIVE_PRIME_INTRON","Benign",,,"rs73510839",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,357,1322,0.27,0,1006,0,14,694,0.0202,0,1008,0,0,978,0,371,5008,0.0740815,,,,,,,,,,,,,,,,,,,,,,,,
416579,"chr19:10339131:A>G","S1PR2",,"NM_004230:c.-43+2749T>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs747337654",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416580,"chr19:10339198:ATCTT>-","S1PR2",,"NM_004230:c.-43+2682_-43+2688delAAGAT","FIVE_PRIME_INTRON","Unknown significance",,,"rs780700740",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416581,"chr19:10339237:C>T","S1PR2",,"NM_004230:c.-43+2643G>A","FIVE_PRIME_INTRON","Benign",,,"rs73015138",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,102,1322,0.0772,184,1006,0.1829,110,694,0.1585,85,1008,0.0843,107,978,0.1094,588,5008,0.117412,,,,,,,,,,,,,,,,,,,,,,,,
416582,"chr19:10339244:C>T","S1PR2",,"NM_004230:c.-43+2636G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs542453446",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416583,"chr19:10339245:G>A","S1PR2",,"NM_004230:c.-43+2635C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs540435679",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416584,"chr19:10339249:C>T","S1PR2",,"NM_004230:c.-43+2631G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs562273366",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416585,"chr19:10339298:C>-","S1PR2",,"NM_004230:c.-43+2582delG","FIVE_PRIME_INTRON","Unknown significance",,,"rs36088779",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416586,"chr19:10339329:G>A","S1PR2",,"NM_004230:c.-43+2551C>T","FIVE_PRIME_INTRON","Benign",,,"rs192477302",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,7,1322,0.0053,0,1006,0,0,694,0,0,1008,0,0,978,0,7,5008,0.00139776,,,,,,,,,,,,,,,,,,,,,,,,
416587,"chr19:10339336:->C","S1PR2",,"NM_004230:c.-43+2544_-43+2545insG","FIVE_PRIME_INTRON","Unknown significance",,,"rs35983252",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416588,"chr19:10339344:A>T","S1PR2",,"NM_004230:c.-43+2536T>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs184800772",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416589,"chr19:10339384:C>T","S1PR2",,"NM_004230:c.-43+2496G>A","FIVE_PRIME_INTRON","Benign",,,"rs80241968",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,72,1322,0.0545,0,1006,0,2,694,0.0029,0,1008,0,0,978,0,74,5008,0.0147764,,,,,,,,,,,,,,,,,,,,,,,,
416590,"chr19:10339392:T>G","S1PR2",,"NM_004230:c.-43+2488A>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs530558605",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,3,978,0.0031,4,5008,0.000798722,,,,,,,,,,,,,,,,,,,,,,,,
416591,"chr19:10339406:C>A","S1PR2",,"NM_004230:c.-43+2474G>T","FIVE_PRIME_INTRON","Benign",,,"rs188089577",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,11,1322,0.0083,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,12,5008,0.00239617,,,,,,,,,,,,,,,,,,,,,,,,
416592,"chr19:10339420:AGA>-","S1PR2",,"NM_004230:c.-43+2460_-43+2464delTCT","FIVE_PRIME_INTRON","Benign",,,"rs569872658",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,45,1322,0.034,0,1006,0,2,694,0.0029,0,1008,0,0,978,0,47,5008,0.00938498,,,,,,,,,,,,,,,,,,,,,,,,
416593,"chr19:10339486:A>T","S1PR2",,"NM_004230:c.-43+2394T>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs760003430",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416594,"chr19:10339496:G>T","S1PR2",,"NM_004230:c.-43+2384C>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs570771621",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2,1322,0.0015,0,1006,0,0,694,0,0,1008,0,0,978,0,2,5008,0.000399361,,,,,,,,,,,,,,,,,,,,,,,,
416595,"chr19:10339520:AGACTC>-","S1PR2",,"NM_004230:c.-43+2360_-43+2367delGAGTCT","FIVE_PRIME_INTRON","Unknown significance",,,"rs757518759",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416596,"chr19:10339530:G>C","S1PR2",,"NM_004230:c.-43+2350C>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs534883766",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416597,"chr19:10339537:TGTC>-","S1PR2",,"NM_004230:c.-43+2343_-43+2348delGACA","FIVE_PRIME_INTRON","Unknown significance",,,"rs746310399",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416598,"chr19:10339560:A>G","S1PR2",,"NM_004230:c.-43+2320T>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs765357367",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416599,"chr19:10339563:A>T","S1PR2",,"NM_004230:c.-43+2317T>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs552915326",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416600,"chr19:10339590:G>A","S1PR2",,"NM_004230:c.-43+2290C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs376051381",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416601,"chr19:10339642:->C","S1PR2",,"NM_004230:c.-43+2238_-43+2239insG","FIVE_PRIME_INTRON","Unknown significance",,,"rs35375426",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416602,"chr19:10339653:C>T","S1PR2",,"NM_004230:c.-43+2227G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs374988732",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416603,"chr19:10339664:C>T","S1PR2",,"NM_004230:c.-43+2216G>A","FIVE_PRIME_INTRON","Benign",,,"rs143577024",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,11,1322,0.0083,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,12,5008,0.00239617,,,,,,,,,,,,,,,,,,,,,,,,
416604,"chr19:10339720:C>T","S1PR2",,"NM_004230:c.-43+2160G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs775372334",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416605,"chr19:10339737:G>A","S1PR2",,"NM_004230:c.-43+2143C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs560784084",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416606,"chr19:10339745:G>T","S1PR2",,"NM_004230:c.-43+2135C>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs535277682",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416607,"chr19:10339775:->C","S1PR2",,"NM_004230:c.-43+2105_-43+2106insG","FIVE_PRIME_INTRON","Benign",,,"rs142165603",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,43,1322,0.0325,0,1006,0,0,694,0,0,1008,0,0,978,0,43,5008,0.00858626,,,,,,,,,,,,,,,,,,,,,,,,
416608,"chr19:10339802:C>T","S1PR2",,"NM_004230:c.-43+2078G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs557470871",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2,1322,0.0015,0,1006,0,0,694,0,0,1008,0,0,978,0,2,5008,0.000399361,,,,,,,,,,,,,,,,,,,,,,,,
416609,"chr19:10339818:G>C","S1PR2",,"NM_004230:c.-43+2062C>G","FIVE_PRIME_INTRON","Benign",,,"rs7250265",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1202,1322,0.9092,818,1006,0.8131,562,694,0.8098,549,1008,0.5446,785,978,0.8027,3916,5008,0.781949,,,,,,,,,,,,,,,,,,,,,,,,
416610,"chr19:10339821:G>A","S1PR2",,"NM_004230:c.-43+2059C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs545796921",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,4,978,0.0041,4,5008,0.000798722,,,,,,,,,,,,,,,,,,,,,,,,
416611,"chr19:10339830:C>T","S1PR2",,"NM_004230:c.-43+2050G>A","FIVE_PRIME_INTRON","Benign",,,"rs114551434",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,24,1322,0.0182,1,1006,0.001,1,694,0.0014,0,1008,0,0,978,0,26,5008,0.00519169,,,,,,,,,,,,,,,,,,,,,,,,
416612,"chr19:10339841:C>T","S1PR2",,"NM_004230:c.-43+2039G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs573216653",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416613,"chr19:10339850:C>A","S1PR2",,"NM_004230:c.-43+2030G>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs540495431",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,1,978,0.001,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416614,"chr19:10339880:A>G","S1PR2",,"NM_004230:c.-43+2000T>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs192593260",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,3,1006,0.003,0,694,0,0,1008,0,0,978,0,4,5008,0.000798722,,,,,,,,,,,,,,,,,,,,,,,,
416615,"chr19:10339890:C>T","S1PR2",,"NM_004230:c.-43+1990G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs751798874",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416616,"chr19:10339897:CTACCC>-","S1PR2",,"NM_004230:c.-43+1983_-43+1990delGGGTAG","FIVE_PRIME_INTRON","Unknown significance",,,"rs780597732",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416617,"chr19:10339943:G>T","S1PR2",,"NM_004230:c.-43+1937C>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs77749851",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416618,"chr19:10339956:T>C","S1PR2",,"NM_004230:c.-43+1924A>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs755880089",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416619,"chr19:10339958:T>C","S1PR2",,"NM_004230:c.-43+1922A>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs75356939",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416620,"chr19:10339962:->A","S1PR2",,"NM_004230:c.-43+1918_-43+1919insT","FIVE_PRIME_INTRON","Unknown significance",,,"rs199954759",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416621,"chr19:10339969:->G","S1PR2",,"NM_004230:c.-43+1911_-43+1912insC","FIVE_PRIME_INTRON","Benign",,,"rs200170566",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,129,1322,0.0976,0,1006,0,4,694,0.0058,0,1008,0,0,978,0,133,5008,0.0265575,,,,,,,,,,,,,,,,,,,,,,,,
416622,"chr19:10339971:A>T","S1PR2",,"NM_004230:c.-43+1909T>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs147869829",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416623,"chr19:10339989:AG>-","S1PR2",,"NM_004230:c.-43+1891_-43+1894delCT","FIVE_PRIME_INTRON","Unknown significance",,,"rs768822440",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416624,"chr19:10339994:C>T","S1PR2",,"NM_004230:c.-43+1886G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs574208766",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,1,978,0.001,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416625,"chr19:10339996:C>T","S1PR2",,"NM_004230:c.-43+1884G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs544467962",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416626,"chr19:10340048:C>T","S1PR2",,"NM_004230:c.-43+1832G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs530876512",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,1,978,0.001,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416627,"chr19:10340112:C>T","S1PR2",,"NM_004230:c.-43+1768G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs766126825",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416628,"chr19:10340127:G>A","S1PR2",,"NM_004230:c.-43+1753C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs373143629",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416629,"chr19:10340146:A>G","S1PR2",,"NM_004230:c.-43+1734T>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs530583034",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416630,"chr19:10340163:A>C","S1PR2",,"NM_004230:c.-43+1717T>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs552221579",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416631,"chr19:10340239:T>C","S1PR2",,"NM_004230:c.-43+1641A>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs184436365",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416632,"chr19:10340246:G>A","S1PR2",,"NM_004230:c.-43+1634C>T","FIVE_PRIME_INTRON","Benign",,,"rs55782435",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,102,1322,0.0772,187,1006,0.1859,110,694,0.1585,85,1008,0.0843,107,978,0.1094,591,5008,0.118011,,,,,,,,,,,,,,,,,,,,,,,,
416633,"chr19:10340257:C>T","S1PR2",,"NM_004230:c.-43+1623G>A","FIVE_PRIME_INTRON","Benign",,,"rs145727324",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,7,1322,0.0053,0,1006,0,0,694,0,0,1008,0,0,978,0,7,5008,0.00139776,,,,,,,,,,,,,,,,,,,,,,,,
416634,"chr19:10340298:T>C","S1PR2",,"NM_004230:c.-43+1582A>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs754930178",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416635,"chr19:10340353:C>T","S1PR2",,"NM_004230:c.-43+1527G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs189671716",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416636,"chr19:10340354:G>A","S1PR2",,"NM_004230:c.-43+1526C>T","FIVE_PRIME_INTRON","Benign",,,"rs111824963",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,59,1322,0.0446,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,60,5008,0.0119808,,,,,,,,,,,,,,,,,,,,,,,,
416637,"chr19:10340367:T>A","S1PR2",,"NM_004230:c.-43+1513A>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs550457124",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,1,978,0.001,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416638,"chr19:10340373:A>G","S1PR2",,"NM_004230:c.-43+1507T>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs142985955",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416639,"chr19:10340428:C>A","S1PR2",,"NM_004230:c.-43+1452G>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs532179990",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416640,"chr19:10340435:C>A","S1PR2",,"NM_004230:c.-43+1445G>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs758013813",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416641,"chr19:10340438:CAATAG>-","S1PR2",,"NM_004230:c.-43+1442_-43+1449delCTATTG","FIVE_PRIME_INTRON","Benign",,,"rs374951256",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,10,1006,0.0099,4,694,0.0058,0,1008,0,0,978,0,15,5008,0.00299521,,,,,,,,,,,,,,,,,,,,,,,,
416642,"chr19:10340445:A>T","S1PR2",,"NM_004230:c.-43+1435T>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs539513643",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2,1322,0.0015,0,1006,0,0,694,0,0,1008,0,0,978,0,2,5008,0.000399361,,,,,,,,,,,,,,,,,,,,,,,,
416643,"chr19:10340450:T>C","S1PR2",,"NM_004230:c.-43+1430A>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs557751193",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416644,"chr19:10340458:C>T","S1PR2",,"NM_004230:c.-43+1422G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs181314892",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416645,"chr19:10340471:C>G","S1PR2",,"NM_004230:c.-43+1409G>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs186063665",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416646,"chr19:10340502:T>C","S1PR2",,"NM_004230:c.-43+1378A>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs556064826",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416647,"chr19:10340517:C>G","S1PR2",,"NM_004230:c.-43+1363G>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs574245775",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416648,"chr19:10340545:G>A","S1PR2",,"NM_004230:c.-43+1335C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs544790989",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416649,"chr19:10340634:G>C","S1PR2",,"NM_004230:c.-43+1246C>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs189268563",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416650,"chr19:10340643:T>A","S1PR2",,"NM_004230:c.-43+1237A>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs207477000",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416651,"chr19:10340654:->AATG","S1PR2",,"NM_004230:c.-43+1226_-43+1227insCATT","FIVE_PRIME_INTRON","Benign",,,"rs111954525",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,626,1322,0.4735,184,1006,0.1829,129,694,0.1859,85,1008,0.0843,108,978,0.1104,1132,5008,0.226038,,,,,,,,,,,,,,,,,,,,,,,,
416652,"chr19:10340654:AATG>-","S1PR2",,"NM_004230:c.-43+1226_-43+1231delCATT","FIVE_PRIME_INTRON","Unknown significance",,,"rs773144161",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416653,"chr19:10340666:->GAAT","S1PR2",,"NM_004230:c.-43+1214_-43+1215insATTC","FIVE_PRIME_INTRON","Unknown significance",,,"rs147120003",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416654,"chr19:10340680:T>-","S1PR2",,"NM_004230:c.-43+1200delA","FIVE_PRIME_INTRON","Unknown significance",,,"rs34035640",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416655,"chr19:10340686:A>G","S1PR2",,"NM_004230:c.-43+1194T>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs562909198",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,1,1006,0.001,0,694,0,0,1008,0,0,978,0,2,5008,0.000399361,,,,,,,,,,,,,,,,,,,,,,,,
416656,"chr19:10340695:C>T","S1PR2",,"NM_004230:c.-43+1185G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs746712053",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416657,"chr19:10340698:G>A","S1PR2",,"NM_004230:c.-43+1182C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs151080390",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416658,"chr19:10340720:T>G","S1PR2",,"NM_004230:c.-43+1160A>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs771298919",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416659,"chr19:10340738:C>T","S1PR2",,"NM_004230:c.-43+1142G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs776929631",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416660,"chr19:10340755:G>A","S1PR2",,"NM_004230:c.-43+1125C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs112557438",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,3,1006,0.003,1,694,0.0014,0,1008,0,1,978,0.001,5,5008,0.000998403,,,,,,,,,,,,,,,,,,,,,,,,
416661,"chr19:10340758:C>T","S1PR2",,"NM_004230:c.-43+1122G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs545944228",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416662,"chr19:10340793:A>C","S1PR2",,"NM_004230:c.-43+1087T>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs564156321",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416663,"chr19:10340794:T>C","S1PR2",,"NM_004230:c.-43+1086A>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs796643207",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416664,"chr19:10340818:C>A","S1PR2",,"NM_004230:c.-43+1062G>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs528133889",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416665,"chr19:10340822:G>T","S1PR2",,"NM_004230:c.-43+1058C>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs546276871",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416666,"chr19:10340854:A>C","S1PR2",,"NM_004230:c.-43+1026T>G","FIVE_PRIME_INTRON","Benign",,,"rs2033493",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1203,1322,0.91,820,1006,0.8151,562,694,0.8098,549,1008,0.5446,784,978,0.8016,3918,5008,0.782348,,,,,,,,,,,,,,,,,,,,,,,,
416667,"chr19:10340861:G>C","S1PR2",,"NM_004230:c.-43+1019C>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs762967545",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416668,"chr19:10340864:G>A","S1PR2",,"NM_004230:c.-43+1016C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs62128727",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416669,"chr19:10340872:C>G","S1PR2",,"NM_004230:c.-43+1008G>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs529136625",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416670,"chr19:10340888:C>G","S1PR2",,"NM_004230:c.-43+992G>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs550766150",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,1,694,0.0014,1,1008,0.001,2,978,0.002,5,5008,0.000998403,,,,,,,,,,,,,,,,,,,,,,,,
416671,"chr19:10340889:T>G","S1PR2",,"NM_004230:c.-43+991A>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs568682360",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416672,"chr19:10340891:G>C","S1PR2",,"NM_004230:c.-43+989C>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs539223876",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,1,1006,0.001,0,694,0,0,1008,0,0,978,0,2,5008,0.000399361,,,,,,,,,,,,,,,,,,,,,,,,
416673,"chr19:10340894:T>A","S1PR2",,"NM_004230:c.-43+986A>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs551493956",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416674,"chr19:10340896:G>A","S1PR2",,"NM_004230:c.-43+984C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs566615967",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2,1322,0.0015,0,1006,0,0,694,0,0,1008,0,0,978,0,2,5008,0.000399361,,,,,,,,,,,,,,,,,,,,,,,,
416675,"chr19:10340897:G>C","S1PR2",,"NM_004230:c.-43+983C>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs181868498",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416676,"chr19:10340907:T>G","S1PR2",,"NM_004230:c.-43+973A>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs534244183",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416677,"chr19:10340912:A>G","S1PR2",,"NM_004230:c.-43+968T>C","FIVE_PRIME_INTRON","Benign",,,"rs2288937",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,102,1322,0.0772,187,1006,0.1859,110,694,0.1585,85,1008,0.0843,107,978,0.1094,591,5008,0.118011,,,,,,,,,,,,,,,,,,,,,,,,
416678,"chr19:10340918:G>T","S1PR2",,"NM_004230:c.-43+962C>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs574282222",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416679,"chr19:10340931:C>T","S1PR2",,"NM_004230:c.-43+949G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs538131507",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,2,1008,0.002,0,978,0,3,5008,0.000599042,,,,,,,,,,,,,,,,,,,,,,,,
416680,"chr19:10340945:C>T","S1PR2",,"NM_004230:c.-43+935G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs549577177",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416681,"chr19:10340947:C>A","S1PR2",,"NM_004230:c.-43+933G>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs556875566",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,1,978,0.001,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416682,"chr19:10340962:C>A","S1PR2",,"NM_004230:c.-43+918G>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs578234027",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416683,"chr19:10340969:C>G","S1PR2",,"NM_004230:c.-43+911G>C","FIVE_PRIME_INTRON","Benign",,,"rs2288938",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,2,1006,0.002,0,694,0,50,1008,0.0496,5,978,0.0051,57,5008,0.0113818,,,,,,,,,,,,,,,,,,,,,,,,
416684,"chr19:10340992:A>G","S1PR2",,"NM_004230:c.-43+888T>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs557932848",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,2,1322,0.0015,0,1006,0,0,694,0,0,1008,0,0,978,0,2,5008,0.000399361,,,,,,,,,,,,,,,,,,,,,,,,
416685,"chr19:10340994:C>A","S1PR2",,"NM_004230:c.-43+886G>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs572927778",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416686,"chr19:10341009:T>A","S1PR2",,"NM_004230:c.-43+871A>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs540234067",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,1,978,0.001,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416687,"chr19:10341011:C>G","S1PR2",,"NM_004230:c.-43+869G>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs561491320",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,1,978,0.001,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416688,"chr19:10341033:C>T","S1PR2",,"NM_004230:c.-43+847G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs529208148",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,1,978,0.001,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416689,"chr19:10341059:G>A","S1PR2",,"NM_004230:c.-43+821C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs544207132",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416690,"chr19:10341071:G>A","S1PR2",,"NM_004230:c.-43+809C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs562425530",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,0,694,0,0,1008,0,2,978,0.002,3,5008,0.000599042,,,,,,,,,,,,,,,,,,,,,,,,
416691,"chr19:10341072:A>G","S1PR2",,"NM_004230:c.-43+808T>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs532998109",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416692,"chr19:10341078:G>A","S1PR2",,"NM_004230:c.-43+802C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs551155994",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416693,"chr19:10341081:G>T","S1PR2",,"NM_004230:c.-43+799C>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs566624535",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416694,"chr19:10341082:C>A","S1PR2",,"NM_004230:c.-43+798G>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs527740564",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416695,"chr19:10341085:C>A","S1PR2",,"NM_004230:c.-43+795G>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs549382740",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,1,978,0.001,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416696,"chr19:10341090:C>G","S1PR2",,"NM_004230:c.-43+790G>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs567584132",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416697,"chr19:10341096:G>C","S1PR2",,"NM_004230:c.-43+784C>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs538224926",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,0,694,0,0,1008,0,1,978,0.001,2,5008,0.000399361,,,,,,,,,,,,,,,,,,,,,,,,
416698,"chr19:10341101:G>-","S1PR2",,"NM_004230:c.-43+779delC","FIVE_PRIME_INTRON","Unknown significance",,,"rs766403532",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416699,"chr19:10341103:G>A","S1PR2",,"NM_004230:c.-43+777C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs774524685",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416700,"chr19:10341130:A>C","S1PR2",,"NM_004230:c.-43+750T>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs755247837",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416701,"chr19:10341137:G>A","S1PR2",,"NM_004230:c.-43+743C>T","FIVE_PRIME_INTRON","Benign",,,"rs114399468",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,78,1322,0.059,0,1006,0,2,694,0.0029,0,1008,0,1,978,0.001,81,5008,0.0161741,3,14,0.214286,0,0,0,0,0,0,0,0,0,0,34,0,0,0,0,0,0,0,3,48,0.0625
416702,"chr19:10341158:G>A","S1PR2",,"NM_004230:c.-43+722C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs571967599",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416703,"chr19:10341197:C>A","S1PR2",,"NM_004230:c.-43+683G>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs762005919",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416704,"chr19:10341198:C>T","S1PR2",,"NM_004230:c.-43+682G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs539239874",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416705,"chr19:10341212:C>G","S1PR2",,"NM_004230:c.-43+668G>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs766181163",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416706,"chr19:10341226:G>A","S1PR2",,"NM_004230:c.-43+654C>T","FIVE_PRIME_INTRON","Benign",,,"rs57318514",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,46,1322,0.0348,0,1006,0,5,694,0.0072,0,1008,0,0,978,0,51,5008,0.0101837,,,,,,,,,,,,,,,,,,,,,,,,
416707,"chr19:10341299:C>T","S1PR2",,"NM_004230:c.-43+581G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs572911091",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,1,978,0.001,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416708,"chr19:10341318:G>T","S1PR2",,"NM_004230:c.-43+562C>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs753521594",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416709,"chr19:10341322:G>A","S1PR2",,"NM_004230:c.-43+558C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs530120779",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416710,"chr19:10341332:C>A","S1PR2",,"NM_004230:c.-43+548G>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs12983553",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416711,"chr19:10341337:C>G","S1PR2",,"NM_004230:c.-43+543G>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs186315882",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416712,"chr19:10341337:C>T","S1PR2",,"NM_004230:c.-43+543G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs186315882",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416713,"chr19:10341340:C>T","S1PR2",,"NM_004230:c.-43+540G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs555418327",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416714,"chr19:10341351:T>G","S1PR2",,"NM_004230:c.-43+529A>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs573587981",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416715,"chr19:10341362:A>T","S1PR2",,"NM_004230:c.-43+518T>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs544185338",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416716,"chr19:10341368:C>T","S1PR2",,"NM_004230:c.-43+512G>A","FIVE_PRIME_INTRON","Benign",,,"rs10424806",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,353,1322,0.267,0,1006,0,14,694,0.0202,0,1008,0,0,978,0,367,5008,0.0732827,,,,,,,,,,,,,,,,,,,,,,,,
416717,"chr19:10341379:C>A","S1PR2",,"NM_004230:c.-43+501G>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs537161875",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416718,"chr19:10341381:C>A","S1PR2",,"NM_004230:c.-43+499G>T","FIVE_PRIME_INTRON","Benign",,,"rs192024884",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,7,1322,0.0053,0,1006,0,0,694,0,0,1008,0,0,978,0,7,5008,0.00139776,,,,,,,,,,,,,,,,,,,,,,,,
416719,"chr19:10341389:G>C","S1PR2",,"NM_004230:c.-43+491C>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs559878273",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416720,"chr19:10341409:A>T","S1PR2",,"NM_004230:c.-43+471T>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs182609837",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416721,"chr19:10341415:G>A","S1PR2",,"NM_004230:c.-43+465C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs527462330",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416722,"chr19:10341438:C>T","S1PR2",,"NM_004230:c.-43+442G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs549247073",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,1,1006,0.001,0,694,0,0,1008,0,0,978,0,2,5008,0.000399361,,,,,,,,,,,,,,,,,,,,,,,,
416723,"chr19:10341439:G>A","S1PR2",,"NM_004230:c.-43+441C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs567741812",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416724,"chr19:10341456:G>A","S1PR2",,"NM_004230:c.-43+424C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs531656170",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,2,694,0.0029,1,1008,0.001,0,978,0,3,5008,0.000599042,,,,,,,,,,,,,,,,,,,,,,,,
416725,"chr19:10341459:G>A","S1PR2",,"NM_004230:c.-43+421C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs146944870",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416726,"chr19:10341466:C>T","S1PR2",,"NM_004230:c.-43+414G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs571979609",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416727,"chr19:10341474:C>G","S1PR2",,"NM_004230:c.-43+406G>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs539304898",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416728,"chr19:10341488:G>T","S1PR2",,"NM_004230:c.-43+392C>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs765046268",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416729,"chr19:10341490:C>G","S1PR2",,"NM_004230:c.-43+390G>C","FIVE_PRIME_INTRON","Benign",,,"rs554428190",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,13,1322,0.0098,0,1006,0,0,694,0,0,1008,0,0,978,0,13,5008,0.00259585,,,,,,,,,,,,,,,,,,,,,,,,
416730,"chr19:10341517:C>G","S1PR2",,"NM_004230:c.-43+363G>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs566170056",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416731,"chr19:10341524:C>G","S1PR2",,"NM_004230:c.-43+356G>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs536835796",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416732,"chr19:10341526:G>A","S1PR2",,"NM_004230:c.-43+354C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs796377092",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416733,"chr19:10341539:T>C","S1PR2",,"NM_004230:c.-43+341A>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs555211102",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416734,"chr19:10341542:C>-","S1PR2",,"NM_004230:c.-43+338delG","FIVE_PRIME_INTRON","Unknown significance",,,"rs767727256",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416735,"chr19:10341548:C>A","S1PR2",,"NM_004230:c.-43+332G>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs573674327",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416736,"chr19:10341548:C>G","S1PR2",,"NM_004230:c.-43+332G>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs573674327",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416737,"chr19:10341553:A>C","S1PR2",,"NM_004230:c.-43+327T>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs62128749",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416738,"chr19:10341583:A>C","S1PR2",,"NM_004230:c.-43+297T>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs537448322",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416739,"chr19:10341601:A>G","S1PR2",,"NM_004230:c.-43+279T>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs555697346",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416740,"chr19:10341603:G>C","S1PR2",,"NM_004230:c.-43+277C>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs577530071",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416741,"chr19:10341615:A>G","S1PR2",,"NM_004230:c.-43+265T>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs544932785",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416742,"chr19:10341616:A>G","S1PR2",,"NM_004230:c.-43+264T>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs560381580",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416743,"chr19:10341624:G>C","S1PR2",,"NM_004230:c.-43+256C>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs572190996",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416744,"chr19:10341638:C>A","S1PR2",,"NM_004230:c.-43+242G>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs542807446",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,2,5008,0.000399361,,,,,,,,,,,,,,,,,,,,,,,,
416745,"chr19:10341639:C>T","S1PR2",,"NM_004230:c.-43+241G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs2288939",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416746,"chr19:10341643:C>T","S1PR2",,"NM_004230:c.-43+237G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs777469644",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416747,"chr19:10341644:G>A","S1PR2",,"NM_004230:c.-43+236C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs531790156",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,1,978,0.001,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416748,"chr19:10341658:G>A","S1PR2",,"NM_004230:c.-43+222C>T","FIVE_PRIME_INTRON","Benign",,,"rs2288940",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,189,1322,0.143,223,1006,0.2217,243,694,0.3501,236,1008,0.2341,256,978,0.2618,1147,5008,0.229034,,,,,,,,,,,,,,,,,,,,,,,,
416749,"chr19:10341663:G>C","S1PR2",,"NM_004230:c.-43+217C>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs565252331",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,1,1008,0.001,0,978,0,2,5008,0.000399361,,,,,,,,,,,,,,,,,,,,,,,,
416750,"chr19:10341666:A>G","S1PR2",,"NM_004230:c.-43+214T>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs532526547",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416751,"chr19:10341670:G>A","S1PR2",,"NM_004230:c.-43+210C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs548141171",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,1,1008,0.001,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416752,"chr19:10341675:G>C","S1PR2",,"NM_004230:c.-43+205C>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs566353132",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416753,"chr19:10341676:C>T","S1PR2",,"NM_004230:c.-43+204G>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs536491421",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416754,"chr19:10341694:G>A","S1PR2",,"NM_004230:c.-43+186C>T","FIVE_PRIME_INTRON","Benign",,,"rs185985023",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,7,1006,0.007,3,694,0.0043,0,1008,0,17,978,0.0174,27,5008,0.00539137,,,,,,,,,,,,,,,,,,,,,,,,
416755,"chr19:10341695:G>C","S1PR2",,"NM_004230:c.-43+185C>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs567256403",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416756,"chr19:10341699:A>G","S1PR2",,"NM_004230:c.-43+181T>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs377560483",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416757,"chr19:10341704:G>A","S1PR2",,"NM_004230:c.-43+176C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs112385110",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416758,"chr19:10341710:G>A","S1PR2",,"NM_004230:c.-43+170C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs780899568",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416759,"chr19:10341719:A>G","S1PR2",,"NM_004230:c.-43+161T>C","FIVE_PRIME_INTRON","Unknown significance",,,"rs537511244",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1,1322,0.0008,0,1006,0,0,694,0,0,1008,0,1,978,0.001,2,5008,0.000399361,,,,,,,,,,,,,,,,,,,,,,,,
416760,"chr19:10341720:T>C","S1PR2",,"NM_004230:c.-43+160A>G","FIVE_PRIME_INTRON","Unknown significance",,,"rs555760354",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,0,694,0,0,1008,0,0,978,0,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416761,"chr19:10341734:G>A","S1PR2",,"NM_004230:c.-43+146C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs191380465",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,5,1322,0.0038,0,1006,0,0,694,0,0,1008,0,0,978,0,5,5008,0.000998403,,,,,,,,,,,,,,,,,,,,,,,,
416762,"chr19:10341759:G>T","S1PR2",,"NM_004230:c.-43+121C>A","FIVE_PRIME_INTRON","Unknown significance",,,"rs538239009",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,0,1006,0,0,694,0,0,1008,0,1,978,0.001,1,5008,0.000199681,,,,,,,,,,,,,,,,,,,,,,,,
416763,"chr19:10341762:G>A","S1PR2",,"NM_004230:c.-43+118C>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs553830481",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,0,1322,0,1,1006,0.001,1,694,0.0014,0,1008,0,0,978,0,2,5008,0.000399361,,,,,,,,,,,,,,,,,,,,,,,,
416764,"chr19:10341873:C>A","S1PR2",,"NM_004230:c.-43+7G>T","FIVE_PRIME_INTRON","Unknown significance",,,"rs569468909",,,,"This variant is a VUS because it does not have enough information.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
416765,"chr19:10341915:A>G","S1PR2",,"NM_004230:c.-78T>C","FIVE_PRIME_EXON","Benign",,,"rs572259005",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,12,1322,0.0091,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,13,5008,0.00259585,,,,,,,,,,,,,,,,,,,,,,,,
416766,"chr19:10341916:G>A","S1PR2",,"NM_004230:c.-79C>T","FIVE_PRIME_EXON","Benign",,,"rs542466473",,,,"This variant contains a MAF in at least one population that meets or exceeds our maximum cutoff of 0.005.",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,12,1322,0.0091,0,1006,0,1,694,0.0014,0,1008,0,0,978,0,13,5008,0.00259585,,,,,,,,,,,,,,,,,,,,,,,