id,variation,vep_hgvs_c,vep_hgvs_p,vep_exon,vep_intron,final_pathogenicity,final_disease,vep_consequence,vep_cadd_phred,overall_max_maf,overall_max_maf_source,gene
606436,3:193310934:T>G,NM_130837.2:c.-233T>G,\N,1/31,\N,Unknown significance,\N,5_prime_UTR_variant,12.34,0.0008,1KG_AFR_AF,OPA1
606437,3:193310940:C>T,NM_130837.2:c.-227C>T,\N,1/31,\N,Unknown significance,\N,5_prime_UTR_variant,9.787,0.0008,1KG_AFR_AF,OPA1
606438,3:193310959:T>A,NM_130837.2:c.-208T>A,\N,1/31,\N,Unknown significance,\N,5_prime_UTR_variant,11.11,0.0023,1KG_AFR_AF,OPA1
606439,3:193310985:C>A,NM_130837.2:c.-182C>A,\N,1/31,\N,Benign,\N,5_prime_UTR_variant,21.4,0.0061,1KG_SAS_AF,OPA1
606440,3:193310995:T>A,NM_130837.2:c.-172T>A,\N,1/31,\N,Unknown significance,\N,5_prime_UTR_variant,12.8,0.0045,1KG_AFR_AF,OPA1
606441,3:193311018:C>A,NM_130837.2:c.-149C>A,\N,1/31,\N,Unknown significance,\N,5_prime_UTR_variant,21.2,\N,\N,OPA1
606442,3:193311022:A>T,NM_130837.2:c.-145A>T,\N,1/31,\N,Unknown significance,\N,5_prime_UTR_variant,20.3,0.001,1KG_SAS_AF,OPA1
606443,3:193311035:C>G,NM_130837.2:c.-132C>G,\N,1/31,\N,Unknown significance,\N,5_prime_UTR_variant,7.13,0.0008,1KG_AFR_AF,OPA1
606444,3:193311053:C>T,NM_130837.2:c.-114C>T,\N,1/31,\N,Benign,\N,5_prime_UTR_variant,14.1,0.0053,1KG_AFR_AF,OPA1
606445,3:193311069:A>G,NM_130837.2:c.-98A>G,\N,1/31,\N,Unknown significance,\N,5_prime_UTR_variant,10.3,0.002,1KG_SAS_AF,OPA1
606446,3:193311080:C>G,NM_130837.2:c.-87C>G,\N,1/31,\N,Benign,\N,5_prime_UTR_variant,18.96,0.0129,1KG_EAS_AF,OPA1
606447,3:193311082:T>C,NM_130837.2:c.-85T>C,\N,1/31,\N,Unknown significance,\N,5_prime_UTR_variant,17.87,\N,\N,OPA1
606448,3:193311113:A>C,NM_130837.2:c.-54A>C,\N,1/31,\N,Unknown significance,\N,5_prime_UTR_variant,3.695,0.001,1KG_SAS_AF,OPA1
606449,3:193311138:G>A,NM_130837.2:c.-29G>A,\N,1/31,\N,Unknown significance,\N,5_prime_UTR_variant,11.1,0.00100705,EXAC_AFR_AF,OPA1
606450,3:193311140:C>T,NM_130837.2:c.-27C>T,\N,1/31,\N,Unknown significance,\N,5_prime_UTR_variant,12.41,0.0008,1KG_AFR_AF,OPA1
606451,3:193311141:G>A,NM_130837.2:c.-26G>A,\N,1/31,\N,Unknown significance,\N,5_prime_UTR_variant,9.022,0.000124782,EVS_EA_AF,OPA1
606452,3:193311146:C>T,NM_130837.2:c.-21C>T,\N,1/31,\N,Unknown significance,\N,5_prime_UTR_variant,10.29,\N,\N,OPA1
606453,3:193311154:C>T,NM_130837.2:c.-13C>T,\N,1/31,\N,Unknown significance,\N,5_prime_UTR_variant,11.22,0.000148765,EXAC_SAS_AF,OPA1
606454,3:193311156:C>T,NM_130837.2:c.-11C>T,\N,1/31,\N,Unknown significance,\N,5_prime_UTR_variant,9.275,0.0008,1KG_AFR_AF,OPA1
606455,3:193311157:C>T,NM_130837.2:c.-10C>T,\N,1/31,\N,Unknown significance,\N,5_prime_UTR_variant,10.5,\N,\N,OPA1
606456,3:193311158:G>A,NM_130837.2:c.-9G>A,\N,1/31,\N,Unknown significance,\N,5_prime_UTR_variant,5.256,0.0001459,EXAC_SAS_AF,OPA1
606457,3:193311159:C>T,NM_130837.2:c.-8C>T,\N,1/31,\N,Unknown significance,\N,5_prime_UTR_variant,8.878,0.000504414,EXAC_NFE_AF,OPA1
606458,3:193311167:A>G,NM_130837.2:c.1A>G,NP_570850.2:p.Met1?,1/31,\N,Unknown significance,\N,start_lost,21.6,\N,\N,OPA1
606459,3:193311167:A>T,NM_130837.2:c.1A>T,NP_570850.2:p.Met1?,1/31,\N,Pathogenic,Optic neuropathy,start_lost,15.24,\N,\N,OPA1
606460,3:193311169:G>T,NM_130837.2:c.3G>T,NP_570850.2:p.Met1?,1/31,\N,Pathogenic,Optic atrophy,start_lost,22.7,\N,\N,OPA1
606461,3:193311172:G>A,NM_130837.2:c.6G>A,NP_570850.2:p.Trp2Ter,1/31,\N,Pathogenic,Optic atrophy 1,stop_gained,36,\N,\N,OPA1
606462,3:193311188:G>T,NM_130837.2:c.22G>T,NP_570850.2:p.Ala8Ser,1/31,\N,Pathogenic,Optic atrophy 1,missense_variant,21.8,\N,\N,OPA1
606463,3:193311196:C>T,NM_130837.2:c.30C>T,NP_570850.2:p.Ala10=,1/31,\N,Unknown significance,\N,splice_region_variant&synonymous_variant,18.47,\N,\N,OPA1
606464,3:193311197:T>C,NM_130837.2:c.31T>C,NP_570850.2:p.Cys11Arg,1/31,\N,Unknown significance,\N,missense_variant&splice_region_variant,23,\N,\N,OPA1
606465,3:193311199:G>A,NM_130837.2:c.32+1G>A,\N,\N,1/30,Pathogenic,Optic atrophy & diabetes,splice_donor_variant,24.1,\N,\N,OPA1
606466,3:193311212:C>T,NM_130837.2:c.32+14C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,8.537,0.002,1KG_EUR_AF,OPA1
606467,3:193311215:A>G,NM_130837.2:c.32+17A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,7.35,0.000121124,EVS_EA_AF,OPA1
606468,3:193311219:G>C,NM_130837.2:c.32+21G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,5.112,0.0015,1KG_AFR_AF,OPA1
606469,3:193311221:C>T,NM_130837.2:c.32+23C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,11.23,\N,\N,OPA1
606470,3:193311222:C>G,NM_130837.2:c.32+24C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,7.973,0.00011636,EXAC_NFE_AF,OPA1
606471,3:193311224:C>T,NM_130837.2:c.32+26C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,7.842,\N,\N,OPA1
606472,3:193311230:T>A,NM_130837.2:c.32+32T>A,\N,\N,1/30,Unknown significance,\N,intron_variant,9.723,0.00023753,EVS_AA_AF,OPA1
606473,3:193311230:T>C,NM_130837.2:c.32+32T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,6.732,0.0008,1KG_AFR_AF,OPA1
606474,3:193311239:C>T,NM_130837.2:c.32+41C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,8.103,0.000693481,EXAC_SAS_AF,OPA1
606475,3:193311242:T>C,NM_130837.2:c.32+44T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,3.613,0.000759878,EXAC_AFR_AF,OPA1
606476,3:193311243:T>G,NM_130837.2:c.32+45T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,5.978,0.000117343,EXAC_NFE_AF,OPA1
606477,3:193311260:T>C,NM_130837.2:c.32+62T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,4.972,0.000722543,EVS_AA_AF,OPA1
606478,3:193311266:T>TA,NM_130837.2:c.32+69dup,\N,\N,1/30,Unknown significance,\N,intron_variant,3.477,\N,\N,OPA1
606479,3:193311267:A>G,NM_130837.2:c.32+69A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,6.466,\N,\N,OPA1
606480,3:193311278:T>C,NM_130837.2:c.32+80T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,6.398,0.0014,1KG_AMR_AF,OPA1
606481,3:193311294:A>G,NM_130837.2:c.32+96A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,8.04,\N,\N,OPA1
606482,3:193311298:C>T,NM_130837.2:c.32+100C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,9.769,0.002,1KG_EAS_AF,OPA1
606483,3:193311338:G>A,NM_130837.2:c.32+140G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,7.795,0.0008,1KG_AFR_AF,OPA1
606484,3:193311361:G>C,NM_130837.2:c.32+163G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.651,0.001,1KG_EAS_AF,OPA1
606485,3:193311441:C>G,NM_130837.2:c.32+243C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,15.01,0.001,1KG_EAS_AF,OPA1
606486,3:193311443:A>G,NM_130837.2:c.32+245A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,14.74,\N,\N,OPA1
606487,3:193311443:A>T,NM_130837.2:c.32+245A>T,\N,\N,1/30,Benign,\N,intron_variant,14.18,0.0053,1KG_AFR_AF,OPA1
606488,3:193311457:C>G,NM_130837.2:c.32+259C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,13.48,\N,\N,OPA1
606489,3:193311478:C>T,NM_130837.2:c.32+280C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,11.84,0.0015,1KG_AFR_AF,OPA1
606490,3:193311484:C>T,NM_130837.2:c.32+286C>T,\N,\N,1/30,Benign,\N,intron_variant,7.596,0.1051,1KG_AFR_AF,OPA1
606491,3:193311495:C>T,NM_130837.2:c.32+297C>T,\N,\N,1/30,Benign,\N,intron_variant,9.029,0.0072,1KG_SAS_AF,OPA1
606492,3:193311565:C>G,NM_130837.2:c.32+367C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,7.295,0.002,1KG_SAS_AF,OPA1
606493,3:193311579:C>T,NM_130837.2:c.32+381C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,8.991,0.003,1KG_EAS_AF,OPA1
606494,3:193311599:A>G,NM_130837.2:c.32+401A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,7.455,0.003,1KG_AFR_AF,OPA1
606495,3:193311603:C>G,NM_130837.2:c.32+405C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,5.734,0.0014,1KG_AMR_AF,OPA1
606496,3:193311606:G>A,NM_130837.2:c.32+408G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,6.98,0.001,1KG_SAS_AF,OPA1
606497,3:193311632:C>T,NM_130837.2:c.32+434C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,10.75,0.0008,1KG_AFR_AF,OPA1
606498,3:193311665:G>C,NM_130837.2:c.32+467G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,2.297,0.001,1KG_SAS_AF,OPA1
606499,3:193311680:A>G,NM_130837.2:c.32+482A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,7.241,\N,\N,OPA1
606500,3:193311685:G>A,NM_130837.2:c.32+487G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,7.788,0.001,1KG_EAS_AF,OPA1
606501,3:193311722:A>G,NM_130837.2:c.32+524A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,12.67,\N,\N,OPA1
606502,3:193311756:C>T,NM_130837.2:c.32+558C>T,\N,\N,1/30,Benign,\N,intron_variant,9.803,0.7795,1KG_AMR_AF,OPA1
606503,3:193311764:C>T,NM_130837.2:c.32+566C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,8.053,0.001,1KG_SAS_AF,OPA1
606504,3:193311785:G>C,NM_130837.2:c.32+587G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,6.907,\N,\N,OPA1
606505,3:193311804:G>A,NM_130837.2:c.32+606G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,5.55,\N,\N,OPA1
606506,3:193311817:T>G,NM_130837.2:c.32+619T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,7.563,\N,\N,OPA1
606507,3:193311824:T>C,NM_130837.2:c.32+626T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,6.831,\N,\N,OPA1
606508,3:193311829:G>A,NM_130837.2:c.32+631G>A,\N,\N,1/30,Benign,\N,intron_variant,5.513,0.0628,1KG_AFR_AF,OPA1
606509,3:193311838:C>T,NM_130837.2:c.32+640C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,8.187,0.0045,1KG_AFR_AF,OPA1
606510,3:193311862:A>G,NM_130837.2:c.32+664A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,4.48,\N,\N,OPA1
606511,3:193311872:C>A,NM_130837.2:c.32+674C>A,\N,\N,1/30,Unknown significance,\N,intron_variant,6.415,\N,\N,OPA1
606512,3:193311927:C>T,NM_130837.2:c.32+729C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.968,\N,\N,OPA1
606513,3:193311931:A>G,NM_130837.2:c.32+733A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,8.965,0.001,1KG_SAS_AF,OPA1
606514,3:193311937:T>C,NM_130837.2:c.32+739T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,7.981,0.0008,1KG_AFR_AF,OPA1
606515,3:193311984:G>T,NM_130837.2:c.32+786G>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.277,0.0008,1KG_AFR_AF,OPA1
606516,3:193312012:C>T,NM_130837.2:c.32+814C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,9.373,\N,\N,OPA1
606517,3:193312039:A>C,NM_130837.2:c.32+841A>C,\N,\N,1/30,Unknown significance,\N,intron_variant,7.771,0.001,1KG_SAS_AF,OPA1
606518,3:193312052:C>G,NM_130837.2:c.32+854C>G,\N,\N,1/30,Benign,\N,intron_variant,3.613,0.0628,1KG_AFR_AF,OPA1
606519,3:193312063:A>C,NM_130837.2:c.32+865A>C,\N,\N,1/30,Unknown significance,\N,intron_variant,5.41,\N,\N,OPA1
606520,3:193312075:C>T,NM_130837.2:c.32+877C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,15.62,\N,\N,OPA1
606521,3:193312091:A>G,NM_130837.2:c.32+893A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,5.468,0.001,1KG_SAS_AF,OPA1
606522,3:193312122:T>G,NM_130837.2:c.32+924T>G,\N,\N,1/30,Benign,\N,intron_variant,6.671,0.0367,1KG_EAS_AF,OPA1
606523,3:193312140:T>G,NM_130837.2:c.32+942T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,5.256,0.0031,1KG_SAS_AF,OPA1
606524,3:193312204:T>C,NM_130837.2:c.32+1006T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.705,\N,\N,OPA1
606525,3:193312207:T>C,NM_130837.2:c.32+1009T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.064,0.0014,1KG_AMR_AF,OPA1
606526,3:193312250:C>G,NM_130837.2:c.32+1052C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.286,\N,\N,OPA1
606527,3:193312277:A>G,NM_130837.2:c.32+1079A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,6.537,0.0008,1KG_AFR_AF,OPA1
606528,3:193312281:A>G,NM_130837.2:c.32+1083A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,6.206,\N,\N,OPA1
606529,3:193312326:G>A,NM_130837.2:c.32+1128G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.387,0.0014,1KG_AMR_AF,OPA1
606530,3:193312326:G>GC,NM_130837.2:c.32+1130dup,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
606531,3:193312364:A>AG,NM_130837.2:c.32+1171dup,\N,\N,1/30,Unknown significance,\N,intron_variant,0.307,0.004,1KG_EAS_AF,OPA1
606532,3:193312400:C>T,NM_130837.2:c.32+1202C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,6.946,\N,\N,OPA1
606533,3:193312405:G>A,NM_130837.2:c.32+1207G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,6.441,0.001,1KG_SAS_AF,OPA1
606534,3:193312420:A>G,NM_130837.2:c.32+1222A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,7.086,\N,\N,OPA1
606535,3:193312467:G>A,NM_130837.2:c.32+1269G>A,\N,\N,1/30,Benign,\N,intron_variant,4.432,0.0113,1KG_AFR_AF,OPA1
606536,3:193312499:C>T,NM_130837.2:c.32+1301C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,12.45,0.001,1KG_EAS_AF,OPA1
606537,3:193312537:G>GT,NM_130837.2:c.32+1341dup,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
606538,3:193312545:T>G,NM_130837.2:c.32+1347T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,5.617,0.0015,1KG_AFR_AF,OPA1
606539,3:193312548:TAGTC>T,NM_130837.2:c.32+1354_32+1357del,\N,\N,1/30,Unknown significance,\N,intron_variant,7.885,0.0029,1KG_AMR_AF,OPA1
606540,3:193312585:C>T,NM_130837.2:c.32+1387C>T,\N,\N,1/30,Benign,\N,intron_variant,7.878,0.0144,1KG_AMR_AF,OPA1
606541,3:193312586:A>C,NM_130837.2:c.32+1388A>C,\N,\N,1/30,Unknown significance,\N,intron_variant,5.333,0.002,1KG_EAS_AF,OPA1
606542,3:193312648:C>T,NM_130837.2:c.32+1450C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,13.48,0.001,1KG_EAS_AF,OPA1
606543,3:193312708:A>G,NM_130837.2:c.32+1510A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,14.72,0.001,1KG_EAS_AF,OPA1
606544,3:193312759:TAAG>T,NM_130837.2:c.32+1567_32+1569del,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
606545,3:193312777:C>T,NM_130837.2:c.32+1579C>T,\N,\N,1/30,Benign,\N,intron_variant,6.312,0.0102,1KG_SAS_AF,OPA1
606546,3:193312778:G>A,NM_130837.2:c.32+1580G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,5.085,\N,\N,OPA1
606547,3:193312782:T>C,NM_130837.2:c.32+1584T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,4.193,0.002,1KG_EUR_AF,OPA1
606548,3:193312789:A>G,NM_130837.2:c.32+1591A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,4.795,0.0008,1KG_AFR_AF,OPA1
606549,3:193312795:T>G,NM_130837.2:c.32+1597T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,6.562,0.001,1KG_SAS_AF,OPA1
606550,3:193312839:A>G,NM_130837.2:c.32+1641A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.797,0.0008,1KG_AFR_AF,OPA1
606551,3:193312937:A>G,NM_130837.2:c.32+1739A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,6.941,0.0045,1KG_AFR_AF,OPA1
606552,3:193312945:AG>T,NM_130837.2:c.32+1747_32+1748delinsT,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
606553,3:193312959:C>T,NM_130837.2:c.32+1761C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.986,\N,\N,OPA1
606554,3:193312975:A>G,NM_130837.2:c.32+1777A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.295,0.0014,1KG_AMR_AF,OPA1
606555,3:193313062:T>G,NM_130837.2:c.32+1864T>G,\N,\N,1/30,Benign,\N,intron_variant,3.053,0.0169,1KG_EAS_AF,OPA1
606556,3:193313069:A>G,NM_130837.2:c.32+1871A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.186,0.0008,1KG_AFR_AF,OPA1
606557,3:193313097:A>G,NM_130837.2:c.32+1899A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,5.797,\N,\N,OPA1
606558,3:193313100:C>T,NM_130837.2:c.32+1902C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,8.619,0.0014,1KG_AMR_AF,OPA1
606559,3:193313137:T>C,NM_130837.2:c.32+1939T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.548,\N,\N,OPA1
606560,3:193313138:T>C,NM_130837.2:c.32+1940T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,4.922,\N,\N,OPA1
606561,3:193313159:G>A,NM_130837.2:c.32+1961G>A,\N,\N,1/30,Benign,\N,intron_variant,4.753,0.0184,1KG_SAS_AF,OPA1
606562,3:193313187:G>T,NM_130837.2:c.32+1989G>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.509,\N,\N,OPA1
606563,3:193313191:A>G,NM_130837.2:c.32+1993A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.63,0.0029,1KG_AMR_AF,OPA1
606564,3:193313196:CAA>C,NM_130837.2:c.32+1999_32+2000del,\N,\N,1/30,Benign,\N,intron_variant,10.88,0.0179,1KG_EAS_AF,OPA1
606565,3:193313231:A>G,NM_130837.2:c.32+2033A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,8.285,\N,\N,OPA1
606566,3:193313258:A>C,NM_130837.2:c.32+2060A>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.372,\N,\N,OPA1
606567,3:193313269:C>G,NM_130837.2:c.32+2071C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,3.15,0.003,1KG_AFR_AF,OPA1
606568,3:193313271:A>G,NM_130837.2:c.32+2073A>G,\N,\N,1/30,Benign,\N,intron_variant,0.044,0.005,1KG_EAS_AF,OPA1
606569,3:193313294:G>A,NM_130837.2:c.32+2096G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.989,\N,\N,OPA1
606570,3:193313325:A>C,NM_130837.2:c.32+2127A>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.067,\N,\N,OPA1
606571,3:193313338:A>G,NM_130837.2:c.32+2140A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,3.514,0.0014,1KG_AMR_AF,OPA1
606572,3:193313378:C>A,NM_130837.2:c.32+2180C>A,\N,\N,1/30,Unknown significance,\N,intron_variant,2.437,\N,\N,OPA1
606573,3:193313378:C>T,NM_130837.2:c.32+2180C>T,\N,\N,1/30,Benign,\N,intron_variant,1.449,0.0151,1KG_AFR_AF,OPA1
606574,3:193313395:T>C,NM_130837.2:c.32+2197T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,8.682,0.001,1KG_EUR_AF,OPA1
606575,3:193313471:G>T,NM_130837.2:c.32+2273G>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.311,\N,\N,OPA1
606576,3:193313494:T>C,NM_130837.2:c.32+2296T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.052,0.001,1KG_EAS_AF,OPA1
606577,3:193313494:T>G,NM_130837.2:c.32+2296T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.186,\N,\N,OPA1
606578,3:193313499:A>C,NM_130837.2:c.32+2301A>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.738,\N,\N,OPA1
606579,3:193313507:TGG>T,NM_130837.2:c.32+2310_32+2311del,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
606580,3:193313516:CAG>C,NM_130837.2:c.32+2319_32+2320del,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
606581,3:193313517:A>G,NM_130837.2:c.32+2319A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.939,\N,\N,OPA1
606582,3:193313540:C>T,NM_130837.2:c.32+2342C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,5.585,0.001,1KG_EUR_AF,OPA1
606583,3:193313555:G>T,NM_130837.2:c.32+2357G>T,\N,\N,1/30,Benign,\N,intron_variant,0.359,0.0053,1KG_AFR_AF,OPA1
606584,3:193313584:CT>C,NM_130837.2:c.32+2389del,\N,\N,1/30,Benign,\N,intron_variant,6.77,0.0198,1KG_EAS_AF,OPA1
606585,3:193313615:A>T,NM_130837.2:c.32+2417A>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.925,0.0043,1KG_AMR_AF,OPA1
606586,3:193313662:C>T,NM_130837.2:c.32+2464C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,3.314,0.001,1KG_EUR_AF,OPA1
606587,3:193313692:C>T,NM_130837.2:c.32+2494C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.969,\N,\N,OPA1
606588,3:193313719:T>C,NM_130837.2:c.32+2521T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,3.648,\N,\N,OPA1
606589,3:193313838:A>G,NM_130837.2:c.32+2640A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,3.372,0.001,1KG_SAS_AF,OPA1
606590,3:193313952:C>T,NM_130837.2:c.32+2754C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.456,\N,\N,OPA1
606591,3:193313961:T>C,NM_130837.2:c.32+2763T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.507,0.0031,1KG_SAS_AF,OPA1
606592,3:193313986:CTT>C,NM_130837.2:c.32+2807_32+2808del,\N,\N,1/30,Unknown significance,\N,intron_variant,2.437,\N,\N,OPA1
606593,3:193313986:CTTT>C,NM_130837.2:c.32+2806_32+2808del,\N,\N,1/30,Benign,\N,intron_variant,2.34,0.4788,1KG_AFR_AF,OPA1
606594,3:193313986:CTTTT>C,NM_130837.2:c.32+2805_32+2808del,\N,\N,1/30,Unknown significance,\N,intron_variant,2.243,\N,\N,OPA1
606595,3:193314004:T>G,NM_130837.2:c.32+2806T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.899,\N,\N,OPA1
606596,3:193314014:A>T,NM_130837.2:c.32+2816A>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.352,\N,\N,OPA1
606597,3:193314070:A>G,NM_130837.2:c.32+2872A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.137,0.002,1KG_SAS_AF,OPA1
606598,3:193314077:A>G,NM_130837.2:c.32+2879A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.89,\N,\N,OPA1
606599,3:193314080:G>A,NM_130837.2:c.32+2882G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,2.709,\N,\N,OPA1
606600,3:193314080:G>C,NM_130837.2:c.32+2882G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.58,\N,\N,OPA1
606601,3:193314081:C>G,NM_130837.2:c.32+2883C>G,\N,\N,1/30,Benign,\N,intron_variant,0.736,0.0496,1KG_EAS_AF,OPA1
606602,3:193314083:A>ACTTTTCTTTT,NM_130837.2:c.32+2892_32+2901dup,\N,\N,1/30,Unknown significance,\N,intron_variant,0.727,\N,\N,OPA1
606603,3:193314083:A>ACTTTTCTTTTCTTTT,NM_130837.2:c.32+2887_32+2901dup,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
606604,3:193314083:A>T,NM_130837.2:c.32+2885A>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.381,\N,\N,OPA1
606605,3:193314085:T>C,NM_130837.2:c.32+2887T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.756,\N,\N,OPA1
606606,3:193314089:C>CCTTTT,NM_130837.2:c.32+2891_32+2892insCTTTT,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
606607,3:193314090:T>C,NM_130837.2:c.32+2892T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.877,\N,\N,OPA1
606608,3:193314090:TTTTCTTTTCCTTTCC>T,NM_130837.2:c.32+2897_32+2911del,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
606609,3:193314095:T>C,NM_130837.2:c.32+2897T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.179,\N,\N,OPA1
606610,3:193314095:T>TTTTCCTTTCCTTTCCTTTCCTTTCC,NM_130837.2:c.32+2906_32+2930dup,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
606611,3:193314095:TTTTCC>T,NM_130837.2:c.32+2926_32+2930del,\N,\N,1/30,Unknown significance,\N,intron_variant,1.847,\N,\N,OPA1
606612,3:193314099:C>CTTTT,NM_130837.2:c.32+2901_32+2902insTTTT,\N,\N,1/30,Unknown significance,\N,intron_variant,1.829,\N,\N,OPA1
606613,3:193314099:C>CTTTTA,NM_130837.2:c.32+2901_32+2902insTTTTA,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
606614,3:193314100:C>T,NM_130837.2:c.32+2902C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.069,\N,\N,OPA1
606615,3:193314105:C>T,NM_130837.2:c.32+2907C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.037,\N,\N,OPA1
606616,3:193314124:C>T,NM_130837.2:c.32+2926C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.107,\N,\N,OPA1
606617,3:193314126:T>TTTCC,NM_130837.2:c.32+2930_32+2931insCCTT,\N,\N,1/30,Unknown significance,\N,intron_variant,0.303,\N,\N,OPA1
606618,3:193314129:T>C,NM_130837.2:c.32+2931T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.216,\N,\N,OPA1
606619,3:193314129:T>TC,NM_130837.2:c.32+2932dup,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
606620,3:193314131:T>TTTCC,NM_130837.2:c.32+2935_32+2936insCCTT,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
606621,3:193314134:T>C,NM_130837.2:c.32+2936T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,2.044,\N,\N,OPA1
606622,3:193314134:T>TC,NM_130837.2:c.32+2937dup,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
606623,3:193314139:T>C,NM_130837.2:c.32+2941T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,2.709,\N,\N,OPA1
606624,3:193314144:T>C,NM_130837.2:c.32+2946T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,2.843,\N,\N,OPA1
606625,3:193314149:T>C,NM_130837.2:c.32+2951T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,3.124,\N,\N,OPA1
606626,3:193314150:C>CTTAA,NM_130837.2:c.32+2955_32+2958dup,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
606627,3:193314150:CTTAA>C,NM_130837.2:c.32+2955_32+2958del,\N,\N,1/30,Unknown significance,\N,intron_variant,7.37,\N,\N,OPA1
606628,3:193314150:CTTAAT>C,NM_130837.2:c.32+2955_32+2959del,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
606629,3:193314153:A>T,NM_130837.2:c.32+2955A>T,\N,\N,1/30,Unknown significance,\N,intron_variant,3.593,\N,\N,OPA1
606630,3:193314154:A>ATTTTC,NM_130837.2:c.32+2978_32+2982dup,\N,\N,1/30,Unknown significance,\N,intron_variant,0.537,\N,\N,OPA1
606631,3:193314154:A>C,NM_130837.2:c.32+2956A>C,\N,\N,1/30,Unknown significance,\N,intron_variant,3.401,\N,\N,OPA1
606632,3:193314154:A>T,NM_130837.2:c.32+2956A>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.945,\N,\N,OPA1
606633,3:193314154:ATTTTC>A,NM_130837.2:c.32+2978_32+2982del,\N,\N,1/30,Unknown significance,\N,intron_variant,5.045,\N,\N,OPA1
606634,3:193314154:ATTTTCTTTTC>A,NM_130837.2:c.32+2973_32+2982del,\N,\N,1/30,Unknown significance,\N,intron_variant,4.121,\N,\N,OPA1
606635,3:193314158:T>C,NM_130837.2:c.32+2960T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,3.303,\N,\N,OPA1
606636,3:193314159:C>CTTAA,NM_130837.2:c.32+2963_32+2964insAATT,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
606637,3:193314163:T>C,NM_130837.2:c.32+2965T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,3.203,\N,\N,OPA1
606638,3:193314170:T>C,NM_130837.2:c.32+2972T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.673,0.0008,1KG_AFR_AF,OPA1
606639,3:193314176:T>G,NM_130837.2:c.32+2978T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,3.224,0.0015,1KG_AFR_AF,OPA1
606640,3:193314176:TTTCTG>T,NM_130837.2:c.32+2983_32+2987del,\N,\N,1/30,Unknown significance,\N,intron_variant,3.075,\N,\N,OPA1
606641,3:193314181:G>T,NM_130837.2:c.32+2983G>T,\N,\N,1/30,Benign,\N,intron_variant,1.613,0.761,1KG_AFR_AF,OPA1
606642,3:193314194:CTT>C,NM_130837.2:c.32+2999_32+3000del,\N,\N,1/30,Benign,\N,intron_variant,3.818,0.4274,1KG_EUR_AF,OPA1
606643,3:193314196:T>TTTC,NM_130837.2:c.32+3001_32+3003dup,\N,\N,1/30,Unknown significance,\N,intron_variant,0.244,\N,\N,OPA1
606644,3:193314196:T>TTTCTTTTC,NM_130837.2:c.32+3001_32+3008dup,\N,\N,1/30,Unknown significance,\N,intron_variant,0.154,\N,\N,OPA1
606645,3:193314198:TC>T,NM_130837.2:c.32+3001del,\N,\N,1/30,Benign,\N,intron_variant,0.089,0.0179,1KG_EAS_AF,OPA1
606646,3:193314199:C>CTTA,NM_130837.2:c.32+3003_32+3004insATT,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
606647,3:193314199:C>CTTTT,NM_130837.2:c.32+3002_32+3005dup,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
606648,3:193314199:C>CTTTTT,NM_130837.2:c.32+3005_32+3006insTTTTT,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
606649,3:193314229:G>A,NM_130837.2:c.32+3031G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.102,\N,\N,OPA1
606650,3:193314259:G>A,NM_130837.2:c.32+3061G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,7.301,0.0008,1KG_AFR_AF,OPA1
606651,3:193314300:A>G,NM_130837.2:c.32+3102A>G,\N,\N,1/30,Benign,\N,intron_variant,2.722,0.0151,1KG_AFR_AF,OPA1
606652,3:193314308:C>CACTGTACATGCACT,NM_130837.2:c.32+3110_32+3111insACTGTACATGCACT,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
606653,3:193314309:G>A,NM_130837.2:c.32+3111G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.564,0.001,1KG_SAS_AF,OPA1
606654,3:193314312:C>T,NM_130837.2:c.32+3114C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.427,\N,\N,OPA1
606655,3:193314313:G>A,NM_130837.2:c.32+3115G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.363,\N,\N,OPA1
606656,3:193314349:T>A,NM_130837.2:c.32+3151T>A,\N,\N,1/30,Unknown significance,\N,intron_variant,3.708,\N,\N,OPA1
606657,3:193314368:A>G,NM_130837.2:c.32+3170A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.028,\N,\N,OPA1
606658,3:193314377:A>G,NM_130837.2:c.32+3179A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,3.425,\N,\N,OPA1
606659,3:193314417:A>G,NM_130837.2:c.32+3219A>G,\N,\N,1/30,Benign,\N,intron_variant,12.11,0.3211,1KG_SAS_AF,OPA1
606660,3:193314452:C>T,NM_130837.2:c.32+3254C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.471,0.001,1KG_EAS_AF,OPA1
606661,3:193314454:A>G,NM_130837.2:c.32+3256A>G,\N,\N,1/30,Benign,\N,intron_variant,1.345,0.0179,1KG_EAS_AF,OPA1
606662,3:193314492:G>A,NM_130837.2:c.32+3294G>A,\N,\N,1/30,Benign,\N,intron_variant,2.618,0.0182,1KG_AFR_AF,OPA1
606663,3:193314509:G>A,NM_130837.2:c.32+3311G>A,\N,\N,1/30,Benign,\N,intron_variant,0.211,0.0367,1KG_EAS_AF,OPA1
606664,3:193314528:T>C,NM_130837.2:c.32+3330T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,2.295,\N,\N,OPA1
606665,3:193314529:C>T,NM_130837.2:c.32+3331C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.864,0.0008,1KG_AFR_AF,OPA1
606666,3:193314533:A>G,NM_130837.2:c.32+3335A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.657,\N,\N,OPA1
606667,3:193314549:C>T,NM_130837.2:c.32+3351C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.508,0.0008,1KG_AFR_AF,OPA1
606668,3:193314566:A>G,NM_130837.2:c.32+3368A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,3.46,\N,\N,OPA1
606669,3:193314572:A>T,NM_130837.2:c.32+3374A>T,\N,\N,1/30,Benign,\N,intron_variant,3.187,0.1051,1KG_AFR_AF,OPA1
606670,3:193314587:A>T,NM_130837.2:c.32+3389A>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.809,0.001,1KG_SAS_AF,OPA1
606671,3:193314594:C>T,NM_130837.2:c.32+3396C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,3.637,\N,\N,OPA1
606672,3:193314595:G>A,NM_130837.2:c.32+3397G>A,\N,\N,1/30,Benign,\N,intron_variant,3.032,0.6172,1KG_AFR_AF,OPA1
606673,3:193314606:A>G,NM_130837.2:c.32+3408A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,3.099,\N,\N,OPA1
606674,3:193314616:C>G,NM_130837.2:c.32+3418C>G,\N,\N,1/30,Benign,\N,intron_variant,3.572,0.2386,1KG_EUR_AF,OPA1
606675,3:193314628:C>T,NM_130837.2:c.32+3430C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,6.807,\N,\N,OPA1
606676,3:193314630:G>A,NM_130837.2:c.32+3432G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,6.204,\N,\N,OPA1
606677,3:193314634:G>C,NM_130837.2:c.32+3436G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,2.748,\N,\N,OPA1
606678,3:193314667:C>T,NM_130837.2:c.32+3469C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.627,\N,\N,OPA1
606679,3:193314694:A>G,NM_130837.2:c.32+3496A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,3.517,\N,\N,OPA1
606680,3:193314702:G>T,NM_130837.2:c.32+3504G>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.108,\N,\N,OPA1
606681,3:193314710:C>T,NM_130837.2:c.32+3512C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,3.843,0.0023,1KG_AFR_AF,OPA1
606682,3:193314748:C>T,NM_130837.2:c.32+3550C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,8.163,\N,\N,OPA1
606683,3:193314778:C>CA,NM_130837.2:c.32+3581dup,\N,\N,1/30,Unknown significance,\N,intron_variant,7.754,\N,\N,OPA1
606684,3:193314782:G>A,NM_130837.2:c.32+3584G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,6.556,0.001,1KG_EAS_AF,OPA1
606685,3:193314795:G>A,NM_130837.2:c.32+3597G>A,\N,\N,1/30,Benign,\N,intron_variant,4.232,0.0179,1KG_EAS_AF,OPA1
606686,3:193314818:C>T,NM_130837.2:c.32+3620C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.207,0.0045,1KG_AFR_AF,OPA1
606687,3:193314822:A>G,NM_130837.2:c.32+3624A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.295,\N,\N,OPA1
606688,3:193314830:G>A,NM_130837.2:c.32+3632G>A,\N,\N,1/30,Benign,\N,intron_variant,2.15,0.0179,1KG_EAS_AF,OPA1
606689,3:193314836:C>G,NM_130837.2:c.32+3638C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.033,\N,\N,OPA1
606690,3:193314996:A>G,NM_130837.2:c.32+3798A>G,\N,\N,1/30,Benign,\N,intron_variant,9.354,0.0216,1KG_AMR_AF,OPA1
606691,3:193315044:C>T,NM_130837.2:c.32+3846C>T,\N,\N,1/30,Benign,\N,intron_variant,4.539,0.0367,1KG_EAS_AF,OPA1
606692,3:193315047:G>T,NM_130837.2:c.32+3849G>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.122,\N,\N,OPA1
606693,3:193315050:G>A,NM_130837.2:c.32+3852G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.094,\N,\N,OPA1
606694,3:193315051:A>G,NM_130837.2:c.32+3853A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.381,0.001,1KG_EAS_AF,OPA1
606695,3:193315081:A>G,NM_130837.2:c.32+3883A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.289,0.001,1KG_EAS_AF,OPA1
606696,3:193315125:G>C,NM_130837.2:c.32+3927G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,2.096,\N,\N,OPA1
606697,3:193315136:A>G,NM_130837.2:c.32+3938A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,7.336,\N,\N,OPA1
606698,3:193315147:A>G,NM_130837.2:c.32+3949A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.551,0.003,1KG_EUR_AF,OPA1
606699,3:193315150:G>C,NM_130837.2:c.32+3952G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.055,0.001,1KG_SAS_AF,OPA1
606700,3:193315158:C>T,NM_130837.2:c.32+3960C>T,\N,\N,1/30,Benign,\N,intron_variant,1.654,0.0212,1KG_AFR_AF,OPA1
606701,3:193315166:C>G,NM_130837.2:c.32+3968C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,6.25,0.0014,1KG_AMR_AF,OPA1
606702,3:193315172:C>T,NM_130837.2:c.32+3974C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,7.046,0.001,1KG_EUR_AF,OPA1
606703,3:193315173:G>A,NM_130837.2:c.32+3975G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,5.802,\N,\N,OPA1
606704,3:193315176:G>A,NM_130837.2:c.32+3978G>A,\N,\N,1/30,Benign,\N,intron_variant,5.916,0.0875,1KG_EUR_AF,OPA1
606705,3:193315189:C>T,NM_130837.2:c.32+3991C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.389,\N,\N,OPA1
606706,3:193315245:C>T,NM_130837.2:c.32+4047C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.44,\N,\N,OPA1
606707,3:193315246:G>A,NM_130837.2:c.32+4048G>A,\N,\N,1/30,Benign,\N,intron_variant,0.18,0.0333,1KG_AFR_AF,OPA1
606708,3:193315270:A>G,NM_130837.2:c.32+4072A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,4.213,0.001,1KG_SAS_AF,OPA1
606709,3:193315276:T>TC,NM_130837.2:c.32+4079dup,\N,\N,1/30,Benign,\N,intron_variant,3.537,0.0121,1KG_AFR_AF,OPA1
606710,3:193315325:C>A,NM_130837.2:c.32+4127C>A,\N,\N,1/30,Benign,\N,intron_variant,2.668,0.0212,1KG_AFR_AF,OPA1
606711,3:193315331:G>T,NM_130837.2:c.32+4133G>T,\N,\N,1/30,Benign,\N,intron_variant,0.28,0.4597,1KG_AMR_AF,OPA1
606712,3:193315343:G>A,NM_130837.2:c.32+4145G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.534,0.0045,1KG_AFR_AF,OPA1
606713,3:193315394:C>T,NM_130837.2:c.32+4196C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,11.89,0.0008,1KG_AFR_AF,OPA1
606714,3:193315407:G>A,NM_130837.2:c.32+4209G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,7.584,\N,\N,OPA1
606715,3:193315407:G>T,NM_130837.2:c.32+4209G>T,\N,\N,1/30,Unknown significance,\N,intron_variant,6.243,\N,\N,OPA1
606716,3:193315419:G>A,NM_130837.2:c.32+4221G>A,\N,\N,1/30,Benign,\N,intron_variant,7.241,0.1051,1KG_AFR_AF,OPA1
606717,3:193315458:T>C,NM_130837.2:c.32+4260T>C,\N,\N,1/30,Benign,\N,intron_variant,0.131,0.5575,1KG_AFR_AF,OPA1
606718,3:193315479:CAAAAA>C,NM_130837.2:c.32+4296_32+4300del,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
606719,3:193315492:A>C,NM_130837.2:c.32+4294A>C,\N,\N,1/30,Benign,\N,intron_variant,8.124,0.0159,1KG_AMR_AF,OPA1
606720,3:193315498:AG>A,NM_130837.2:c.32+4301del,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
606721,3:193315503:T>C,NM_130837.2:c.32+4305T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,16.5,0.001,1KG_EAS_AF,OPA1
606722,3:193315508:A>G,NM_130837.2:c.32+4310A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,17.99,0.0008,1KG_AFR_AF,OPA1
606723,3:193315521:G>A,NM_130837.2:c.32+4323G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,20.4,0.0023,1KG_AFR_AF,OPA1
606724,3:193315573:C>T,NM_130837.2:c.32+4375C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.261,\N,\N,OPA1
606725,3:193315577:T>C,NM_130837.2:c.32+4379T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,4.104,0.0014,1KG_AMR_AF,OPA1
606726,3:193315592:T>C,NM_130837.2:c.32+4394T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.172,0.001,1KG_EUR_AF,OPA1
606727,3:193315593:A>G,NM_130837.2:c.32+4395A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.932,\N,\N,OPA1
606728,3:193315612:C>T,NM_130837.2:c.32+4414C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.548,\N,\N,OPA1
606729,3:193315615:C>T,NM_130837.2:c.32+4417C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.732,0.0014,1KG_AMR_AF,OPA1
606730,3:193315678:C>A,NM_130837.2:c.32+4480C>A,\N,\N,1/30,Unknown significance,\N,intron_variant,13.27,\N,\N,OPA1
606731,3:193315720:T>C,NM_130837.2:c.32+4522T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,14.04,0.0008,1KG_AFR_AF,OPA1
606732,3:193315748:G>T,NM_130837.2:c.32+4550G>T,\N,\N,1/30,Benign,\N,intron_variant,11.51,0.0166,1KG_AFR_AF,OPA1
606733,3:193315826:T>G,NM_130837.2:c.32+4628T>G,\N,\N,1/30,Benign,\N,intron_variant,2.968,0.0106,1KG_AFR_AF,OPA1
606734,3:193315839:C>T,NM_130837.2:c.32+4641C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.586,\N,\N,OPA1
606735,3:193315852:A>G,NM_130837.2:c.32+4654A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.928,0.0014,1KG_AMR_AF,OPA1
606736,3:193315855:G>A,NM_130837.2:c.32+4657G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,3.616,0.001,1KG_SAS_AF,OPA1
606737,3:193315864:C>A,NM_130837.2:c.32+4666C>A,\N,\N,1/30,Benign,\N,intron_variant,3.091,0.0136,1KG_AFR_AF,OPA1
606738,3:193315864:C>T,NM_130837.2:c.32+4666C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.66,\N,\N,OPA1
606739,3:193315878:A>G,NM_130837.2:c.32+4680A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.445,0.001,1KG_EAS_AF,OPA1
606740,3:193315905:A>G,NM_130837.2:c.32+4707A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.451,0.001,1KG_SAS_AF,OPA1
606741,3:193315936:T>C,NM_130837.2:c.32+4738T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,9.55,\N,\N,OPA1
606742,3:193315944:G>A,NM_130837.2:c.32+4746G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,9.309,\N,\N,OPA1
606743,3:193315957:G>C,NM_130837.2:c.32+4759G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,2.271,\N,\N,OPA1
606744,3:193315993:A>C,NM_130837.2:c.32+4795A>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.619,0.001,1KG_SAS_AF,OPA1
606745,3:193316026:A>C,NM_130837.2:c.32+4828A>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.63,\N,\N,OPA1
606746,3:193316035:G>A,NM_130837.2:c.32+4837G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,4.704,\N,\N,OPA1
606747,3:193316048:A>G,NM_130837.2:c.32+4850A>G,\N,\N,1/30,Benign,\N,intron_variant,1.292,0.4284,1KG_EUR_AF,OPA1
606748,3:193316062:G>A,NM_130837.2:c.32+4864G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,3.493,\N,\N,OPA1
606749,3:193316067:A>G,NM_130837.2:c.32+4869A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.583,0.0008,1KG_AFR_AF,OPA1
606750,3:193316100:C>G,NM_130837.2:c.32+4902C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.811,\N,\N,OPA1
606751,3:193316112:G>A,NM_130837.2:c.32+4914G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,5.949,\N,\N,OPA1
606752,3:193316119:A>G,NM_130837.2:c.32+4921A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,9.537,\N,\N,OPA1
606753,3:193316130:T>C,NM_130837.2:c.32+4932T>C,\N,\N,1/30,Benign,\N,intron_variant,12.03,0.005,1KG_EUR_AF,OPA1
606754,3:193316132:AG>A,NM_130837.2:c.32+4935del,\N,\N,1/30,Unknown significance,\N,intron_variant,12.53,0.003,1KG_AFR_AF,OPA1
606755,3:193316140:G>A,NM_130837.2:c.32+4942G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,9.681,\N,\N,OPA1
606756,3:193316146:C>G,NM_130837.2:c.32+4948C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,4.713,\N,\N,OPA1
606757,3:193316182:GC>G,NM_130837.2:c.32+4985del,\N,\N,1/30,Unknown significance,\N,intron_variant,4.643,\N,\N,OPA1
606758,3:193316186:A>C,NM_130837.2:c.32+4988A>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.328,0.001,1KG_EAS_AF,OPA1
606759,3:193316257:G>A,NM_130837.2:c.32+5059G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,3.272,0.003,1KG_AFR_AF,OPA1
606760,3:193316271:G>A,NM_130837.2:c.32+5073G>A,\N,\N,1/30,Benign,\N,intron_variant,10.49,0.0227,1KG_AFR_AF,OPA1
606761,3:193316315:G>C,NM_130837.2:c.32+5117G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.063,0.001,1KG_EUR_AF,OPA1
606762,3:193316320:A>C,NM_130837.2:c.32+5122A>C,\N,\N,1/30,Benign,\N,intron_variant,0.56,0.0257,1KG_AFR_AF,OPA1
606763,3:193316329:A>G,NM_130837.2:c.32+5131A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.73,0.0043,1KG_AMR_AF,OPA1
606764,3:193316335:C>T,NM_130837.2:c.32+5137C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.351,0.002,1KG_EUR_AF,OPA1
606765,3:193316336:A>C,NM_130837.2:c.32+5138A>C,\N,\N,1/30,Unknown significance,\N,intron_variant,2.226,\N,\N,OPA1
606766,3:193316397:G>A,NM_130837.2:c.32+5199G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.373,\N,\N,OPA1
606767,3:193316432:G>A,NM_130837.2:c.32+5234G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.108,\N,\N,OPA1
606768,3:193316434:A>G,NM_130837.2:c.32+5236A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,3.445,0.0014,1KG_AMR_AF,OPA1
606769,3:193316464:TAAG>T,NM_130837.2:c.32+5267_32+5269del,\N,\N,1/30,Benign,\N,intron_variant,7.788,0.0367,1KG_EAS_AF,OPA1
606770,3:193316491:A>G,NM_130837.2:c.32+5293A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.966,0.001,1KG_SAS_AF,OPA1
606771,3:193316504:AGATTATT>A,NM_130837.2:c.32+5317_32+5323del,\N,\N,1/30,Benign,\N,intron_variant,7.532,0.0179,1KG_EAS_AF,OPA1
606772,3:193316520:A>G,NM_130837.2:c.32+5322A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.105,0.0014,1KG_AMR_AF,OPA1
606773,3:193316524:C>T,NM_130837.2:c.32+5326C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.505,\N,\N,OPA1
606774,3:193316546:T>C,NM_130837.2:c.32+5348T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,4.758,0.002,1KG_EAS_AF,OPA1
606775,3:193316558:C>T,NM_130837.2:c.32+5360C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.048,0.001,1KG_SAS_AF,OPA1
606776,3:193316560:A>T,NM_130837.2:c.32+5362A>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.872,0.0014,1KG_AMR_AF,OPA1
606777,3:193316565:G>A,NM_130837.2:c.32+5367G>A,\N,\N,1/30,Benign,\N,intron_variant,1.514,0.0378,1KG_SAS_AF,OPA1
606778,3:193316574:G>C,NM_130837.2:c.32+5376G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.614,\N,\N,OPA1
606779,3:193316588:A>T,NM_130837.2:c.32+5390A>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.892,\N,\N,OPA1
606780,3:193316633:T>A,NM_130837.2:c.32+5435T>A,\N,\N,1/30,Benign,\N,intron_variant,11.05,0.0367,1KG_EAS_AF,OPA1
606781,3:193316657:A>G,NM_130837.2:c.32+5459A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.759,0.001,1KG_SAS_AF,OPA1
606782,3:193316668:G>A,NM_130837.2:c.32+5470G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,5.799,\N,\N,OPA1
606783,3:193316703:A>G,NM_130837.2:c.32+5505A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,9.83,\N,\N,OPA1
606784,3:193316705:C>T,NM_130837.2:c.32+5507C>T,\N,\N,1/30,Benign,\N,intron_variant,9.422,0.3211,1KG_SAS_AF,OPA1
606785,3:193316706:G>A,NM_130837.2:c.32+5508G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,8.83,0.0015,1KG_AFR_AF,OPA1
606786,3:193316733:G>A,NM_130837.2:c.32+5535G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,2.971,\N,\N,OPA1
606787,3:193316740:T>C,NM_130837.2:c.32+5542T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.71,0.001,1KG_EUR_AF,OPA1
606788,3:193316774:G>C,NM_130837.2:c.32+5576G>C,\N,\N,1/30,Benign,\N,intron_variant,1.153,0.0149,1KG_EAS_AF,OPA1
606789,3:193316784:TGTG>T,NM_130837.2:c.32+5590_32+5592del,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
606790,3:193316817:C>T,NM_130837.2:c.32+5619C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,5.484,\N,\N,OPA1
606791,3:193316821:T>C,NM_130837.2:c.32+5623T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.027,0.003,1KG_EAS_AF,OPA1
606792,3:193316838:A>G,NM_130837.2:c.32+5640A>G,\N,\N,1/30,Benign,\N,intron_variant,1.053,0.2386,1KG_EUR_AF,OPA1
606793,3:193316852:T>A,NM_130837.2:c.32+5654T>A,\N,\N,1/30,Unknown significance,\N,intron_variant,5.08,0.0008,1KG_AFR_AF,OPA1
606794,3:193316856:T>C,NM_130837.2:c.32+5658T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,2.04,\N,\N,OPA1
606795,3:193316878:T>G,NM_130837.2:c.32+5680T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,5.991,\N,\N,OPA1
606796,3:193316889:C>T,NM_130837.2:c.32+5691C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,4.683,0.002,1KG_EAS_AF,OPA1
606797,3:193316895:A>G,NM_130837.2:c.32+5697A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,3.671,0.002,1KG_SAS_AF,OPA1
606798,3:193316969:A>G,NM_130837.2:c.32+5771A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.24,0.0008,1KG_AFR_AF,OPA1
606799,3:193317036:C>T,NM_130837.2:c.32+5838C>T,\N,\N,1/30,Benign,\N,intron_variant,0.581,0.0367,1KG_EAS_AF,OPA1
606800,3:193317039:A>G,NM_130837.2:c.32+5841A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.841,0.0014,1KG_AMR_AF,OPA1
606801,3:193317048:A>G,NM_130837.2:c.32+5850A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.396,\N,\N,OPA1
606802,3:193317052:C>T,NM_130837.2:c.32+5854C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.009,0.001,1KG_EAS_AF,OPA1
606803,3:193317074:C>T,NM_130837.2:c.32+5876C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.227,0.0008,1KG_AFR_AF,OPA1
606804,3:193317140:C>T,NM_130837.2:c.32+5942C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.663,0.0008,1KG_AFR_AF,OPA1
606805,3:193317143:G>C,NM_130837.2:c.32+5945G>C,\N,\N,1/30,Benign,\N,intron_variant,0.376,0.0257,1KG_AFR_AF,OPA1
606806,3:193317149:T>G,NM_130837.2:c.32+5951T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,4.328,0.001,1KG_SAS_AF,OPA1
606807,3:193317189:C>CT,NM_130837.2:c.32+6003dup,\N,\N,1/30,Unknown significance,\N,intron_variant,3.147,\N,\N,OPA1
606808,3:193317189:CT>C,NM_130837.2:c.32+6003del,\N,\N,1/30,Unknown significance,\N,intron_variant,4.546,\N,\N,OPA1
606809,3:193317210:T>C,NM_130837.2:c.32+6012T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.693,0.0029,1KG_AMR_AF,OPA1
606810,3:193317218:C>A,NM_130837.2:c.32+6020C>A,\N,\N,1/30,Benign,\N,intron_variant,0.165,0.0068,1KG_AFR_AF,OPA1
606811,3:193317229:CT>C,NM_130837.2:c.32+6038del,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
606812,3:193317251:A>G,NM_130837.2:c.32+6053A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.43,0.0008,1KG_AFR_AF,OPA1
606813,3:193317299:A>G,NM_130837.2:c.32+6101A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.296,0.0038,1KG_AFR_AF,OPA1
606814,3:193317304:C>A,NM_130837.2:c.32+6106C>A,\N,\N,1/30,Unknown significance,\N,intron_variant,6.392,0.0008,1KG_AFR_AF,OPA1
606815,3:193317317:T>C,NM_130837.2:c.32+6119T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.514,\N,\N,OPA1
606816,3:193317321:G>T,NM_130837.2:c.32+6123G>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.284,0.0014,1KG_AMR_AF,OPA1
606817,3:193317330:A>G,NM_130837.2:c.32+6132A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.062,0.0008,1KG_AFR_AF,OPA1
606818,3:193317335:G>A,NM_130837.2:c.32+6137G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.302,0.0008,1KG_AFR_AF,OPA1
606819,3:193317351:T>G,NM_130837.2:c.32+6153T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.417,0.0008,1KG_AFR_AF,OPA1
606820,3:193317419:G>A,NM_130837.2:c.32+6221G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.214,0.001,1KG_SAS_AF,OPA1
606821,3:193317457:C>A,NM_130837.2:c.32+6259C>A,\N,\N,1/30,Unknown significance,\N,intron_variant,8.657,0.0023,1KG_AFR_AF,OPA1
606822,3:193317467:A>G,NM_130837.2:c.32+6269A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,4.974,0.0014,1KG_AMR_AF,OPA1
606823,3:193317498:C>A,NM_130837.2:c.32+6300C>A,\N,\N,1/30,Unknown significance,\N,intron_variant,5.346,0.0008,1KG_AFR_AF,OPA1
606824,3:193317501:T>G,NM_130837.2:c.32+6303T>G,\N,\N,1/30,Benign,\N,intron_variant,2.525,0.0367,1KG_EAS_AF,OPA1
606825,3:193317546:T>G,NM_130837.2:c.32+6348T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.588,0.001,1KG_SAS_AF,OPA1
606826,3:193317577:T>A,NM_130837.2:c.32+6379T>A,\N,\N,1/30,Unknown significance,\N,intron_variant,6.064,\N,\N,OPA1
606827,3:193317592:G>A,NM_130837.2:c.32+6394G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.413,0.0008,1KG_AFR_AF,OPA1
606828,3:193317609:C>T,NM_130837.2:c.32+6411C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.588,0.0008,1KG_AFR_AF,OPA1
606829,3:193317610:G>A,NM_130837.2:c.32+6412G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,8.74,0.001,1KG_SAS_AF,OPA1
606830,3:193317672:A>G,NM_130837.2:c.32+6474A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.99,\N,\N,OPA1
606831,3:193317690:C>G,NM_130837.2:c.32+6492C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.11,\N,\N,OPA1
606832,3:193317732:C>T,NM_130837.2:c.32+6534C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.063,0.0008,1KG_AFR_AF,OPA1
606833,3:193317733:G>A,NM_130837.2:c.32+6535G>A,\N,\N,1/30,Benign,\N,intron_variant,1.351,0.0367,1KG_EAS_AF,OPA1
606834,3:193317749:C>T,NM_130837.2:c.32+6551C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.072,0.003,1KG_EUR_AF,OPA1
606835,3:193317750:G>A,NM_130837.2:c.32+6552G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.057,0.0014,1KG_AMR_AF,OPA1
606836,3:193317753:G>A,NM_130837.2:c.32+6555G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.859,\N,\N,OPA1
606837,3:193317760:C>T,NM_130837.2:c.32+6562C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.558,\N,\N,OPA1
606838,3:193317777:G>C,NM_130837.2:c.32+6579G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.333,\N,\N,OPA1
606839,3:193317779:G>A,NM_130837.2:c.32+6581G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,3.329,\N,\N,OPA1
606840,3:193317794:G>A,NM_130837.2:c.32+6596G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.451,0.001,1KG_EAS_AF|1KG_EUR_AF,OPA1
606841,3:193317794:G>C,NM_130837.2:c.32+6596G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.078,\N,\N,OPA1
606842,3:193317801:T>C,NM_130837.2:c.32+6603T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.765,0.0015,1KG_AFR_AF,OPA1
606843,3:193317808:A>G,NM_130837.2:c.32+6610A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.638,\N,\N,OPA1
606844,3:193317840:A>G,NM_130837.2:c.32+6642A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.035,\N,\N,OPA1
606845,3:193317862:T>C,NM_130837.2:c.32+6664T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.999,0.0008,1KG_AFR_AF,OPA1
606846,3:193317867:A>G,NM_130837.2:c.32+6669A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.712,0.0008,1KG_AFR_AF,OPA1
606847,3:193317888:G>A,NM_130837.2:c.32+6690G>A,\N,\N,1/30,Benign,\N,intron_variant,0.033,0.0598,1KG_AFR_AF,OPA1
606848,3:193317912:G>A,NM_130837.2:c.32+6714G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,3.677,0.001,1KG_SAS_AF,OPA1
606849,3:193317916:G>A,NM_130837.2:c.32+6718G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.187,0.001,1KG_EAS_AF,OPA1
606850,3:193317924:C>T,NM_130837.2:c.32+6726C>T,\N,\N,1/30,Benign,\N,intron_variant,2.218,0.0257,1KG_AFR_AF,OPA1
606851,3:193317974:C>T,NM_130837.2:c.32+6776C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,4.222,\N,\N,OPA1
606852,3:193318002:T>C,NM_130837.2:c.32+6804T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,2.501,\N,\N,OPA1
606853,3:193318006:C>T,NM_130837.2:c.32+6808C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.446,0.0023,1KG_AFR_AF,OPA1
606854,3:193318025:C>T,NM_130837.2:c.32+6827C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.843,\N,\N,OPA1
606855,3:193318043:T>C,NM_130837.2:c.32+6845T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.128,\N,\N,OPA1
606856,3:193318049:C>T,NM_130837.2:c.32+6851C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,3.799,0.001,1KG_SAS_AF,OPA1
606857,3:193318056:T>TG,NM_130837.2:c.32+6860dup,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
606858,3:193318057:G>A,NM_130837.2:c.32+6859G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,2.343,0.0008,1KG_AFR_AF,OPA1
606859,3:193318100:A>G,NM_130837.2:c.32+6902A>G,\N,\N,1/30,Benign,\N,intron_variant,0.454,0.0051,1KG_SAS_AF,OPA1
606860,3:193318115:A>G,NM_130837.2:c.32+6917A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.943,0.001,1KG_EAS_AF,OPA1
606861,3:193318121:G>T,NM_130837.2:c.32+6923G>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.965,\N,\N,OPA1
606862,3:193318131:G>A,NM_130837.2:c.32+6933G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,2.857,0.0008,1KG_AFR_AF,OPA1
606863,3:193318199:A>G,NM_130837.2:c.32+7001A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.758,0.001,1KG_EUR_AF,OPA1
606864,3:193318226:C>T,NM_130837.2:c.32+7028C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,5.123,0.001,1KG_SAS_AF,OPA1
606865,3:193318250:T>C,NM_130837.2:c.32+7052T>C,\N,\N,1/30,Benign,\N,intron_variant,0.094,0.5855,1KG_AFR_AF,OPA1
606866,3:193318250:TG>CA,NM_130837.2:c.32+7052_32+7053inv,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
606867,3:193318251:G>A,NM_130837.2:c.32+7053G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.747,0.0008,1KG_AFR_AF,OPA1
606868,3:193318291:G>A,NM_130837.2:c.32+7093G>A,\N,\N,1/30,Benign,\N,intron_variant,0.952,0.5855,1KG_AFR_AF,OPA1
606869,3:193318299:G>A,NM_130837.2:c.32+7101G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,2.542,\N,\N,OPA1
606870,3:193318307:G>A,NM_130837.2:c.32+7109G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.098,\N,\N,OPA1
606871,3:193318309:A>G,NM_130837.2:c.32+7111A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.766,0.0008,1KG_AFR_AF,OPA1
606872,3:193318327:T>C,NM_130837.2:c.32+7129T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.381,0.001,1KG_EUR_AF,OPA1
606873,3:193318354:C>G,NM_130837.2:c.32+7156C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,8.116,0.0014,1KG_AMR_AF,OPA1
606874,3:193318372:A>G,NM_130837.2:c.32+7174A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,7.838,\N,\N,OPA1
606875,3:193318381:G>C,NM_130837.2:c.32+7183G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.007,\N,\N,OPA1
606876,3:193318390:T>C,NM_130837.2:c.32+7192T>C,\N,\N,1/30,Benign,\N,intron_variant,0.15,0.0174,1KG_SAS_AF,OPA1
606877,3:193318395:G>A,NM_130837.2:c.32+7197G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,2.503,\N,\N,OPA1
606878,3:193318408:CAG>C,NM_130837.2:c.32+7213_32+7214del,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
606879,3:193318422:G>C,NM_130837.2:c.32+7224G>C,\N,\N,1/30,Benign,\N,intron_variant,0.257,0.0179,1KG_EAS_AF,OPA1
606880,3:193318425:G>A,NM_130837.2:c.32+7227G>A,\N,\N,1/30,Benign,\N,intron_variant,0.378,0.0248,1KG_EAS_AF,OPA1
606881,3:193318427:A>G,NM_130837.2:c.32+7229A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.103,\N,\N,OPA1
606882,3:193318439:A>G,NM_130837.2:c.32+7241A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.441,\N,\N,OPA1
606883,3:193318447:T>G,NM_130837.2:c.32+7249T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.727,0.003,1KG_EAS_AF,OPA1
606884,3:193318452:C>T,NM_130837.2:c.32+7254C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.132,0.001,1KG_EAS_AF|1KG_SAS_AF,OPA1
606885,3:193318453:G>A,NM_130837.2:c.32+7255G>A,\N,\N,1/30,Benign,\N,intron_variant,0.223,0.0179,1KG_EUR_AF,OPA1
606886,3:193318468:G>A,NM_130837.2:c.32+7270G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,3.325,0.0008,1KG_AFR_AF,OPA1
606887,3:193318482:C>G,NM_130837.2:c.32+7284C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.035,\N,\N,OPA1
606888,3:193318484:C>T,NM_130837.2:c.32+7286C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.002,0.0014,1KG_AMR_AF,OPA1
606889,3:193318515:A>G,NM_130837.2:c.32+7317A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,7.043,\N,\N,OPA1
606890,3:193318518:A>G,NM_130837.2:c.32+7320A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,7.106,0.001,1KG_EAS_AF|1KG_SAS_AF,OPA1
606891,3:193318546:T>C,NM_130837.2:c.32+7348T>C,\N,\N,1/30,Benign,\N,intron_variant,2.435,0.0628,1KG_AFR_AF,OPA1
606892,3:193318576:C>T,NM_130837.2:c.32+7378C>T,\N,\N,1/30,Benign,\N,intron_variant,0.386,0.4284,1KG_EUR_AF,OPA1
606893,3:193318599:C>T,NM_130837.2:c.32+7401C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,6.002,0.0008,1KG_AFR_AF,OPA1
606894,3:193318603:C>G,NM_130837.2:c.32+7405C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,3.53,\N,\N,OPA1
606895,3:193318612:T>C,NM_130837.2:c.32+7414T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.558,0.0014,1KG_AMR_AF,OPA1
606896,3:193318617:G>A,NM_130837.2:c.32+7419G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.881,0.0008,1KG_AFR_AF,OPA1
606897,3:193318623:C>T,NM_130837.2:c.32+7425C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.923,0.001,1KG_EUR_AF,OPA1
606898,3:193318632:A>G,NM_130837.2:c.32+7434A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.183,\N,\N,OPA1
606899,3:193318635:T>G,NM_130837.2:c.32+7437T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.551,\N,\N,OPA1
606900,3:193318637:G>A,NM_130837.2:c.32+7439G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.93,0.0043,1KG_AMR_AF,OPA1
606901,3:193318654:G>A,NM_130837.2:c.32+7456G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,2.569,\N,\N,OPA1
606902,3:193318741:A>T,NM_130837.2:c.32+7543A>T,\N,\N,1/30,Benign,\N,intron_variant,0.767,0.0053,1KG_AFR_AF,OPA1
606903,3:193318762:A>G,NM_130837.2:c.32+7564A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.71,0.001,1KG_SAS_AF,OPA1
606904,3:193318803:T>G,NM_130837.2:c.32+7605T>G,\N,\N,1/30,Benign,\N,intron_variant,3.413,0.0053,1KG_AFR_AF,OPA1
606905,3:193318819:C>T,NM_130837.2:c.32+7621C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.88,\N,\N,OPA1
606906,3:193318827:G>A,NM_130837.2:c.32+7629G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.352,\N,\N,OPA1
606907,3:193318833:T>C,NM_130837.2:c.32+7635T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.199,0.001,1KG_EUR_AF,OPA1
606908,3:193318852:G>A,NM_130837.2:c.32+7654G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.445,0.0008,1KG_AFR_AF,OPA1
606909,3:193318860:T>C,NM_130837.2:c.32+7662T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,2.021,0.0015,1KG_AFR_AF,OPA1
606910,3:193318868:G>C,NM_130837.2:c.32+7670G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.08,\N,\N,OPA1
606911,3:193318893:T>C,NM_130837.2:c.32+7695T>C,\N,\N,1/30,Benign,\N,intron_variant,12.19,0.0051,1KG_SAS_AF,OPA1
606912,3:193318923:T>C,NM_130837.2:c.32+7725T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.963,0.0029,1KG_AMR_AF,OPA1
606913,3:193318940:G>T,NM_130837.2:c.32+7742G>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.106,0.002,1KG_SAS_AF,OPA1
606914,3:193318951:A>T,NM_130837.2:c.32+7753A>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.717,\N,\N,OPA1
606915,3:193318955:A>G,NM_130837.2:c.32+7757A>G,\N,\N,1/30,Benign,\N,intron_variant,1.179,0.0337,1KG_SAS_AF,OPA1
606916,3:193318974:C>T,NM_130837.2:c.32+7776C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.111,\N,\N,OPA1
606917,3:193318984:G>A,NM_130837.2:c.32+7786G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,2.826,0.001,1KG_SAS_AF,OPA1
606918,3:193318987:C>T,NM_130837.2:c.32+7789C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,4.104,\N,\N,OPA1
606919,3:193319013:C>T,NM_130837.2:c.32+7815C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,4.817,\N,\N,OPA1
606920,3:193319033:T>C,NM_130837.2:c.32+7835T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.375,\N,\N,OPA1
606921,3:193319038:C>T,NM_130837.2:c.32+7840C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.502,\N,\N,OPA1
606922,3:193319039:G>A,NM_130837.2:c.32+7841G>A,\N,\N,1/30,Benign,\N,intron_variant,0.489,0.0053,1KG_AFR_AF,OPA1
606923,3:193319039:G>T,NM_130837.2:c.32+7841G>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.163,\N,\N,OPA1
606924,3:193319046:A>G,NM_130837.2:c.32+7848A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.77,\N,\N,OPA1
606925,3:193319051:C>G,NM_130837.2:c.32+7853C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.698,\N,\N,OPA1
606926,3:193319097:C>T,NM_130837.2:c.32+7899C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,3.305,\N,\N,OPA1
606927,3:193319112:G>A,NM_130837.2:c.32+7914G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.331,\N,\N,OPA1
606928,3:193319152:G>A,NM_130837.2:c.32+7954G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.091,0.001,1KG_SAS_AF,OPA1
606929,3:193319238:A>G,NM_130837.2:c.32+8040A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.449,0.0008,1KG_AFR_AF,OPA1
606930,3:193319259:A>C,NM_130837.2:c.32+8061A>C,\N,\N,1/30,Benign,\N,intron_variant,8.913,0.0367,1KG_EAS_AF,OPA1
606931,3:193319284:G>C,NM_130837.2:c.32+8086G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,13.63,\N,\N,OPA1
606932,3:193319389:T>G,NM_130837.2:c.32+8191T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,5.09,0.0008,1KG_AFR_AF,OPA1
606933,3:193319405:G>A,NM_130837.2:c.32+8207G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.324,\N,\N,OPA1
606934,3:193319441:T>C,NM_130837.2:c.32+8243T>C,\N,\N,1/30,Benign,\N,intron_variant,1.201,0.0129,1KG_AFR_AF,OPA1
606935,3:193319466:A>G,NM_130837.2:c.32+8268A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.921,0.0015,1KG_AFR_AF,OPA1
606936,3:193319488:A>G,NM_130837.2:c.32+8290A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.691,0.0031,1KG_SAS_AF,OPA1
606937,3:193319495:A>G,NM_130837.2:c.32+8297A>G,\N,\N,1/30,Benign,\N,intron_variant,0.938,0.0053,1KG_AFR_AF,OPA1
606938,3:193319500:C>T,NM_130837.2:c.32+8302C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.521,0.0023,1KG_AFR_AF,OPA1
606939,3:193319501:G>A,NM_130837.2:c.32+8303G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.036,0.001,1KG_EAS_AF,OPA1
606940,3:193319521:A>T,NM_130837.2:c.32+8323A>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.787,0.001,1KG_EUR_AF,OPA1
606941,3:193319525:GT>G,NM_130837.2:c.32+8333del,\N,\N,1/30,Benign,\N,intron_variant,5.141,0.0257,1KG_AFR_AF,OPA1
606942,3:193319560:G>GA,NM_130837.2:c.32+8367dup,\N,\N,1/30,Unknown significance,\N,intron_variant,0.67,\N,\N,OPA1
606943,3:193319610:T>C,NM_130837.2:c.32+8412T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,10.18,\N,\N,OPA1
606944,3:193319624:A>G,NM_130837.2:c.32+8426A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,10.87,\N,\N,OPA1
606945,3:193319662:T>C,NM_130837.2:c.32+8464T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,4.939,0.001,1KG_EUR_AF,OPA1
606946,3:193319665:T>C,NM_130837.2:c.32+8467T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.104,\N,\N,OPA1
606947,3:193319673:C>T,NM_130837.2:c.32+8475C>T,\N,\N,1/30,Benign,\N,intron_variant,0.183,0.0179,1KG_EAS_AF,OPA1
606948,3:193319675:T>C,NM_130837.2:c.32+8477T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,3.417,\N,\N,OPA1
606949,3:193319689:C>T,NM_130837.2:c.32+8491C>T,\N,\N,1/30,Benign,\N,intron_variant,4.553,0.0628,1KG_AFR_AF,OPA1
606950,3:193319704:T>A,NM_130837.2:c.32+8506T>A,\N,\N,1/30,Unknown significance,\N,intron_variant,5.83,\N,\N,OPA1
606951,3:193319724:G>T,NM_130837.2:c.32+8526G>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.781,\N,\N,OPA1
606952,3:193319736:A>G,NM_130837.2:c.32+8538A>G,\N,\N,1/30,Benign,\N,intron_variant,2.688,0.0072,1KG_SAS_AF,OPA1
606953,3:193319737:A>G,NM_130837.2:c.32+8539A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.725,\N,\N,OPA1
606954,3:193319787:A>G,NM_130837.2:c.32+8589A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,4.191,\N,\N,OPA1
606955,3:193319802:A>G,NM_130837.2:c.32+8604A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.859,\N,\N,OPA1
606956,3:193319838:A>G,NM_130837.2:c.32+8640A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.913,\N,\N,OPA1
606957,3:193319848:G>A,NM_130837.2:c.32+8650G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,2.741,0.0023,1KG_AFR_AF,OPA1
606958,3:193319884:A>T,NM_130837.2:c.32+8686A>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.078,\N,\N,OPA1
606959,3:193319903:A>G,NM_130837.2:c.32+8705A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.905,\N,\N,OPA1
606960,3:193319905:C>T,NM_130837.2:c.32+8707C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.018,0.0038,1KG_AFR_AF,OPA1
606961,3:193319913:A>G,NM_130837.2:c.32+8715A>G,\N,\N,1/30,Benign,\N,intron_variant,1.52,0.0179,1KG_EAS_AF,OPA1
606962,3:193319984:C>T,NM_130837.2:c.32+8786C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.469,\N,\N,OPA1
606963,3:193319988:G>A,NM_130837.2:c.32+8790G>A,\N,\N,1/30,Benign,\N,intron_variant,0.146,0.025,1KG_AFR_AF,OPA1
606964,3:193320057:C>A,NM_130837.2:c.32+8859C>A,\N,\N,1/30,Unknown significance,\N,intron_variant,2.219,\N,\N,OPA1
606965,3:193320112:C>T,NM_130837.2:c.32+8914C>T,\N,\N,1/30,Benign,\N,intron_variant,0.099,0.0308,1KG_EUR_AF,OPA1
606966,3:193320116:G>T,NM_130837.2:c.32+8918G>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.919,0.001,1KG_EAS_AF,OPA1
606967,3:193320127:A>C,NM_130837.2:c.32+8929A>C,\N,\N,1/30,Unknown significance,\N,intron_variant,6.415,0.0014,1KG_AMR_AF,OPA1
606968,3:193320149:G>A,NM_130837.2:c.32+8951G>A,\N,\N,1/30,Benign,\N,intron_variant,3.178,0.5847,1KG_AFR_AF,OPA1
606969,3:193320153:G>A,NM_130837.2:c.32+8955G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.485,\N,\N,OPA1
606970,3:193320154:G>T,NM_130837.2:c.32+8956G>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.597,\N,\N,OPA1
606971,3:193320187:T>G,NM_130837.2:c.32+8989T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,11.04,\N,\N,OPA1
606972,3:193320210:T>C,NM_130837.2:c.32+9012T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.559,\N,\N,OPA1
606973,3:193320223:T>A,NM_130837.2:c.32+9025T>A,\N,\N,1/30,Unknown significance,\N,intron_variant,6.959,\N,\N,OPA1
606974,3:193320248:C>T,NM_130837.2:c.32+9050C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,8.421,\N,\N,OPA1
606975,3:193320249:G>A,NM_130837.2:c.32+9051G>A,\N,\N,1/30,Benign,\N,intron_variant,5.055,0.3214,1KG_EAS_AF,OPA1
606976,3:193320276:A>G,NM_130837.2:c.32+9078A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,6.733,0.0015,1KG_AFR_AF,OPA1
606977,3:193320296:G>A,NM_130837.2:c.32+9098G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,7.777,0.001,1KG_EUR_AF,OPA1
606978,3:193320321:T>A,NM_130837.2:c.32+9123T>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.53,\N,\N,OPA1
606979,3:193320345:G>A,NM_130837.2:c.32+9147G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,3.809,\N,\N,OPA1
606980,3:193320346:A>C,NM_130837.2:c.32+9148A>C,\N,\N,1/30,Unknown significance,\N,intron_variant,2.382,\N,\N,OPA1
606981,3:193320380:C>T,NM_130837.2:c.32+9182C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.911,\N,\N,OPA1
606982,3:193320416:A>G,NM_130837.2:c.32+9218A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.425,0.0014,1KG_AMR_AF,OPA1
606983,3:193320441:T>C,NM_130837.2:c.32+9243T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.701,\N,\N,OPA1
606984,3:193320473:C>G,NM_130837.2:c.32+9275C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.128,0.001,1KG_SAS_AF,OPA1
606985,3:193320492:C>CAA,NM_130837.2:c.32+9295_32+9296dup,\N,\N,1/30,Benign,\N,intron_variant,2.255,0.0053,1KG_AFR_AF,OPA1
606986,3:193320514:G>T,NM_130837.2:c.32+9316G>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.637,\N,\N,OPA1
606987,3:193320521:G>A,NM_130837.2:c.32+9323G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,7.881,\N,\N,OPA1
606988,3:193320537:A>G,NM_130837.2:c.32+9339A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,10.16,\N,\N,OPA1
606989,3:193320596:CT>C,NM_130837.2:c.32+9399del,\N,\N,1/30,Benign,\N,intron_variant,6.242,0.0257,1KG_AFR_AF,OPA1
606990,3:193320607:G>T,NM_130837.2:c.32+9409G>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.256,0.0038,1KG_AFR_AF,OPA1
606991,3:193320626:C>T,NM_130837.2:c.32+9428C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,6.659,0.001,1KG_EAS_AF,OPA1
606992,3:193320655:C>A,NM_130837.2:c.32+9457C>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.842,0.0008,1KG_AFR_AF,OPA1
606993,3:193320662:A>G,NM_130837.2:c.32+9464A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.201,0.001,1KG_EUR_AF,OPA1
606994,3:193320665:G>C,NM_130837.2:c.32+9467G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.362,0.0014,1KG_AMR_AF,OPA1
606995,3:193320730:A>G,NM_130837.2:c.32+9532A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,13.92,0.004,1KG_EAS_AF,OPA1
606996,3:193320736:A>G,NM_130837.2:c.32+9538A>G,\N,\N,1/30,Benign,\N,intron_variant,13.57,0.4284,1KG_EUR_AF,OPA1
606997,3:193320816:T>C,NM_130837.2:c.32+9618T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.589,\N,\N,OPA1
606998,3:193320880:A>T,NM_130837.2:c.32+9682A>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.277,\N,\N,OPA1
606999,3:193320909:A>AT,NM_130837.2:c.32+9717dup,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
607000,3:193320916:C>G,NM_130837.2:c.32+9718C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,3.044,0.0008,1KG_AFR_AF,OPA1
607001,3:193320943:A>G,NM_130837.2:c.32+9745A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,4.82,\N,\N,OPA1
607002,3:193320960:G>C,NM_130837.2:c.32+9762G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.79,\N,\N,OPA1
607003,3:193320971:T>C,NM_130837.2:c.32+9773T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,4.282,\N,\N,OPA1
607004,3:193320999:A>G,NM_130837.2:c.32+9801A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.535,\N,\N,OPA1
607005,3:193321002:C>T,NM_130837.2:c.32+9804C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.087,0.0008,1KG_AFR_AF,OPA1
607006,3:193321003:G>A,NM_130837.2:c.32+9805G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.402,0.001,1KG_EAS_AF,OPA1
607007,3:193321010:C>T,NM_130837.2:c.32+9812C>T,\N,\N,1/30,Benign,\N,intron_variant,0.603,0.005,1KG_EAS_AF,OPA1
607008,3:193321011:G>A,NM_130837.2:c.32+9813G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.634,\N,\N,OPA1
607009,3:193321037:G>A,NM_130837.2:c.32+9839G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.12,0.0014,1KG_AMR_AF,OPA1
607010,3:193321044:T>A,NM_130837.2:c.32+9846T>A,\N,\N,1/30,Unknown significance,\N,intron_variant,6.379,0.0029,1KG_AMR_AF,OPA1
607011,3:193321087:C>T,NM_130837.2:c.32+9889C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.595,0.002,1KG_EAS_AF,OPA1
607012,3:193321088:G>A,NM_130837.2:c.32+9890G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.499,\N,\N,OPA1
607013,3:193321109:G>A,NM_130837.2:c.32+9911G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,4.936,\N,\N,OPA1
607014,3:193321115:G>A,NM_130837.2:c.32+9917G>A,\N,\N,1/30,Benign,\N,intron_variant,2.7,0.5832,1KG_AFR_AF,OPA1
607015,3:193321144:G>A,NM_130837.2:c.32+9946G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.023,\N,\N,OPA1
607016,3:193321164:A>T,NM_130837.2:c.32+9966A>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.205,\N,\N,OPA1
607017,3:193321173:G>A,NM_130837.2:c.32+9975G>A,\N,\N,1/30,Benign,\N,intron_variant,1.483,0.4284,1KG_EUR_AF,OPA1
607018,3:193321197:T>A,NM_130837.2:c.32+9999T>A,\N,\N,1/30,Unknown significance,\N,intron_variant,5.226,0.001,1KG_EAS_AF,OPA1
607019,3:193321219:A>G,NM_130837.2:c.32+10021A>G,\N,\N,1/30,Benign,\N,intron_variant,1.454,0.0051,1KG_SAS_AF,OPA1
607020,3:193321238:T>A,NM_130837.2:c.32+10040T>A,\N,\N,1/30,Unknown significance,\N,intron_variant,8.468,\N,\N,OPA1
607021,3:193321295:A>T,NM_130837.2:c.32+10097A>T,\N,\N,1/30,Unknown significance,\N,intron_variant,5.678,\N,\N,OPA1
607022,3:193321321:C>A,NM_130837.2:c.32+10123C>A,\N,\N,1/30,Unknown significance,\N,intron_variant,4.335,\N,\N,OPA1
607023,3:193321322:A>G,NM_130837.2:c.32+10124A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,3.276,0.001,1KG_EAS_AF,OPA1
607024,3:193321343:A>G,NM_130837.2:c.32+10145A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,4.734,\N,\N,OPA1
607025,3:193321380:A>G,NM_130837.2:c.32+10182A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.651,0.0008,1KG_AFR_AF,OPA1
607026,3:193321386:C>T,NM_130837.2:c.32+10188C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.718,\N,\N,OPA1
607027,3:193321388:T>C,NM_130837.2:c.32+10190T>C,\N,\N,1/30,Benign,\N,intron_variant,1.325,0.0119,1KG_EUR_AF,OPA1
607028,3:193321409:A>G,NM_130837.2:c.32+10211A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.867,0.0008,1KG_AFR_AF,OPA1
607029,3:193321416:G>A,NM_130837.2:c.32+10218G>A,\N,\N,1/30,Benign,\N,intron_variant,0.864,0.0367,1KG_EAS_AF,OPA1
607030,3:193321472:G>A,NM_130837.2:c.32+10274G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,2.678,\N,\N,OPA1
607031,3:193321513:T>C,NM_130837.2:c.32+10315T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.868,\N,\N,OPA1
607032,3:193321524:A>T,NM_130837.2:c.32+10326A>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.299,0.001,1KG_EAS_AF,OPA1
607033,3:193321617:C>G,NM_130837.2:c.32+10419C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.713,\N,\N,OPA1
607034,3:193321643:C>T,NM_130837.2:c.32+10445C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.651,0.001,1KG_EUR_AF,OPA1
607035,3:193321665:C>G,NM_130837.2:c.32+10467C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.257,\N,\N,OPA1
607036,3:193321669:A>C,NM_130837.2:c.32+10471A>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.232,0.001,1KG_EAS_AF,OPA1
607037,3:193321677:C>G,NM_130837.2:c.32+10479C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.014,0.002,1KG_SAS_AF,OPA1
607038,3:193321678:G>A,NM_130837.2:c.32+10480G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.029,0.0015,1KG_AFR_AF,OPA1
607039,3:193321707:A>G,NM_130837.2:c.32+10509A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.583,\N,\N,OPA1
607040,3:193321711:CAG>C,NM_130837.2:c.32+10516_32+10517del,\N,\N,1/30,Benign,\N,intron_variant,6.118,0.0499,1KG_AFR_AF,OPA1
607041,3:193321713:G>C,NM_130837.2:c.32+10515G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.1,0.002,1KG_EAS_AF,OPA1
607042,3:193321746:G>A,NM_130837.2:c.32+10548G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,9.972,\N,\N,OPA1
607043,3:193321758:A>T,NM_130837.2:c.32+10560A>T,\N,\N,1/30,Unknown significance,\N,intron_variant,9.177,\N,\N,OPA1
607044,3:193321810:C>A,NM_130837.2:c.32+10612C>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.78,0.003,1KG_EUR_AF,OPA1
607045,3:193321810:C>T,NM_130837.2:c.32+10612C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.068,0.003,1KG_EAS_AF,OPA1
607046,3:193321846:G>A,NM_130837.2:c.32+10648G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.076,\N,\N,OPA1
607047,3:193321846:G>GT,NM_130837.2:c.32+10649dup,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
607048,3:193321869:C>A,NM_130837.2:c.33-10643C>A,\N,\N,1/30,Unknown significance,\N,intron_variant,4.211,0.002,1KG_SAS_AF,OPA1
607049,3:193321876:T>C,NM_130837.2:c.33-10636T>C,\N,\N,1/30,Benign,\N,intron_variant,1.869,0.4121,1KG_SAS_AF,OPA1
607050,3:193321911:C>T,NM_130837.2:c.33-10601C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.411,0.0008,1KG_AFR_AF,OPA1
607051,3:193321981:A>C,NM_130837.2:c.33-10531A>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.228,0.001,1KG_SAS_AF,OPA1
607052,3:193321991:T>C,NM_130837.2:c.33-10521T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.313,0.001,1KG_SAS_AF,OPA1
607053,3:193322046:T>A,NM_130837.2:c.33-10466T>A,\N,\N,1/30,Unknown significance,\N,intron_variant,10.07,0.001,1KG_EUR_AF,OPA1
607054,3:193322071:TG>T,NM_130837.2:c.33-10436del,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
607055,3:193322073:G>T,NM_130837.2:c.33-10439G>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.343,\N,\N,OPA1
607056,3:193322132:G>A,NM_130837.2:c.33-10380G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.245,0.0014,1KG_AMR_AF,OPA1
607057,3:193322143:T>G,NM_130837.2:c.33-10369T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,9.593,\N,\N,OPA1
607058,3:193322146:T>G,NM_130837.2:c.33-10366T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,8.893,0.0015,1KG_AFR_AF,OPA1
607059,3:193322152:A>G,NM_130837.2:c.33-10360A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,10.8,0.0014,1KG_AMR_AF,OPA1
607060,3:193322190:A>C,NM_130837.2:c.33-10322A>C,\N,\N,1/30,Unknown significance,\N,intron_variant,9.515,0.0014,1KG_AMR_AF,OPA1
607061,3:193322237:C>T,NM_130837.2:c.33-10275C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.038,0.001,1KG_SAS_AF,OPA1
607062,3:193322254:G>C,NM_130837.2:c.33-10258G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.087,0.001,1KG_SAS_AF,OPA1
607063,3:193322269:C>T,NM_130837.2:c.33-10243C>T,\N,\N,1/30,Benign,\N,intron_variant,2.727,0.0121,1KG_AFR_AF,OPA1
607064,3:193322291:C>T,NM_130837.2:c.33-10221C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,3.719,\N,\N,OPA1
607065,3:193322320:A>G,NM_130837.2:c.33-10192A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.364,0.002,1KG_SAS_AF,OPA1
607066,3:193322325:A>G,NM_130837.2:c.33-10187A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.361,0.001,1KG_SAS_AF,OPA1
607067,3:193322384:T>A,NM_130837.2:c.33-10128T>A,\N,\N,1/30,Unknown significance,\N,intron_variant,3.382,\N,\N,OPA1
607068,3:193322388:G>A,NM_130837.2:c.33-10124G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.744,0.002,1KG_EAS_AF,OPA1
607069,3:193322398:C>T,NM_130837.2:c.33-10114C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.235,0.004,1KG_EUR_AF,OPA1
607070,3:193322409:G>A,NM_130837.2:c.33-10103G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,3.081,0.001,1KG_EUR_AF,OPA1
607071,3:193322424:C>T,NM_130837.2:c.33-10088C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.967,0.0031,1KG_SAS_AF,OPA1
607072,3:193322439:C>T,NM_130837.2:c.33-10073C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.962,0.0029,1KG_AMR_AF,OPA1
607073,3:193322475:C>T,NM_130837.2:c.33-10037C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.954,0.001,1KG_EAS_AF,OPA1
607074,3:193322504:C>T,NM_130837.2:c.33-10008C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.746,0.001,1KG_EAS_AF,OPA1
607075,3:193322541:C>T,NM_130837.2:c.33-9971C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.074,\N,\N,OPA1
607076,3:193322542:G>A,NM_130837.2:c.33-9970G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.226,0.0029,1KG_AMR_AF,OPA1
607077,3:193322563:C>T,NM_130837.2:c.33-9949C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,4.157,0.0014,1KG_AMR_AF,OPA1
607078,3:193322564:G>T,NM_130837.2:c.33-9948G>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.428,\N,\N,OPA1
607079,3:193322574:A>C,NM_130837.2:c.33-9938A>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.035,0.0015,1KG_AFR_AF,OPA1
607080,3:193322630:C>T,NM_130837.2:c.33-9882C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,3.97,0.002,1KG_EUR_AF,OPA1
607081,3:193322649:C>A,NM_130837.2:c.33-9863C>A,\N,\N,1/30,Unknown significance,\N,intron_variant,2.44,\N,\N,OPA1
607082,3:193322649:C>CAAAAA,NM_130837.2:c.33-9852_33-9848dup,\N,\N,1/30,Unknown significance,\N,intron_variant,1.826,\N,\N,OPA1
607083,3:193322649:C>CAAAAAAA,NM_130837.2:c.33-9854_33-9848dup,\N,\N,1/30,Unknown significance,\N,intron_variant,1.589,\N,\N,OPA1
607084,3:193322649:CAA>C,NM_130837.2:c.33-9849_33-9848del,\N,\N,1/30,Unknown significance,\N,intron_variant,3.429,\N,\N,OPA1
607085,3:193322658:A>AAAAAAAG,NM_130837.2:c.33-9842_33-9836dup,\N,\N,1/30,Benign,\N,intron_variant,0.026,0.3185,1KG_EAS_AF,OPA1
607086,3:193322658:A>AAAAAG,NM_130837.2:c.33-9850_33-9849insGAAAA,\N,\N,1/30,Unknown significance,\N,intron_variant,0.03,\N,\N,OPA1
607087,3:193322658:A>G,NM_130837.2:c.33-9854A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.599,\N,\N,OPA1
607088,3:193322664:A>AAAAAT,NM_130837.2:c.33-9848_33-9847insAAAAT,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
607089,3:193322664:AG>A,NM_130837.2:c.33-9847del,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
607090,3:193322665:G>A,NM_130837.2:c.33-9847G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.118,\N,\N,OPA1
607091,3:193322750:A>G,NM_130837.2:c.33-9762A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.567,\N,\N,OPA1
607092,3:193322757:G>A,NM_130837.2:c.33-9755G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.499,0.0015,1KG_AFR_AF,OPA1
607093,3:193322769:A>G,NM_130837.2:c.33-9743A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.946,0.0008,1KG_AFR_AF,OPA1
607094,3:193322774:A>C,NM_130837.2:c.33-9738A>C,\N,\N,1/30,Benign,\N,intron_variant,1.308,0.0053,1KG_AFR_AF,OPA1
607095,3:193322785:A>G,NM_130837.2:c.33-9727A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,3.537,\N,\N,OPA1
607096,3:193322801:C>T,NM_130837.2:c.33-9711C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.692,\N,\N,OPA1
607097,3:193322833:G>A,NM_130837.2:c.33-9679G>A,\N,\N,1/30,Benign,\N,intron_variant,0.455,0.0348,1KG_EUR_AF,OPA1
607098,3:193322833:G>C,NM_130837.2:c.33-9679G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.079,\N,\N,OPA1
607099,3:193322843:C>T,NM_130837.2:c.33-9669C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.558,\N,\N,OPA1
607100,3:193322870:T>G,NM_130837.2:c.33-9642T>G,\N,\N,1/30,Benign,\N,intron_variant,2.321,0.4284,1KG_EUR_AF,OPA1
607101,3:193322894:T>C,NM_130837.2:c.33-9618T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.035,0.0008,1KG_AFR_AF,OPA1
607102,3:193322899:T>C,NM_130837.2:c.33-9613T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.539,0.001,1KG_EUR_AF,OPA1
607103,3:193322918:C>T,NM_130837.2:c.33-9594C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,4.453,\N,\N,OPA1
607104,3:193322967:G>T,NM_130837.2:c.33-9545G>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.596,\N,\N,OPA1
607105,3:193323019:G>C,NM_130837.2:c.33-9493G>C,\N,\N,1/30,Benign,\N,intron_variant,3.068,0.0121,1KG_AFR_AF,OPA1
607106,3:193323026:T>G,NM_130837.2:c.33-9486T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,9.313,0.0014,1KG_AMR_AF,OPA1
607107,3:193323062:A>G,NM_130837.2:c.33-9450A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,7.423,\N,\N,OPA1
607108,3:193323076:A>G,NM_130837.2:c.33-9436A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.309,0.001,1KG_SAS_AF,OPA1
607109,3:193323079:T>G,NM_130837.2:c.33-9433T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.596,0.0014,1KG_AMR_AF,OPA1
607110,3:193323087:T>C,NM_130837.2:c.33-9425T>C,\N,\N,1/30,Benign,\N,intron_variant,1.022,0.0179,1KG_EAS_AF,OPA1
607111,3:193323100:G>C,NM_130837.2:c.33-9412G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.13,\N,\N,OPA1
607112,3:193323112:C>T,NM_130837.2:c.33-9400C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.602,0.001,1KG_SAS_AF,OPA1
607113,3:193323145:A>G,NM_130837.2:c.33-9367A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,10.23,0.0015,1KG_AFR_AF,OPA1
607114,3:193323157:C>T,NM_130837.2:c.33-9355C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,6.707,0.0015,1KG_AFR_AF,OPA1
607115,3:193323160:G>A,NM_130837.2:c.33-9352G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,7.447,\N,\N,OPA1
607116,3:193323170:A>G,NM_130837.2:c.33-9342A>G,\N,\N,1/30,Benign,\N,intron_variant,4.659,0.0363,1KG_AFR_AF,OPA1
607117,3:193323179:T>C,NM_130837.2:c.33-9333T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,5.911,\N,\N,OPA1
607118,3:193323197:A>T,NM_130837.2:c.33-9315A>T,\N,\N,1/30,Unknown significance,\N,intron_variant,5.671,0.0014,1KG_AMR_AF,OPA1
607119,3:193323208:A>G,NM_130837.2:c.33-9304A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.947,0.001,1KG_EUR_AF,OPA1
607120,3:193323261:G>A,NM_130837.2:c.33-9251G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,6.186,0.0023,1KG_AFR_AF,OPA1
607121,3:193323284:T>G,NM_130837.2:c.33-9228T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,4.774,0.001,1KG_EUR_AF,OPA1
607122,3:193323327:G>A,NM_130837.2:c.33-9185G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,8.984,0.0014,1KG_AMR_AF,OPA1
607123,3:193323342:A>G,NM_130837.2:c.33-9170A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.527,0.002,1KG_EAS_AF,OPA1
607124,3:193323348:A>G,NM_130837.2:c.33-9164A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.617,0.0014,1KG_AMR_AF,OPA1
607125,3:193323360:C>T,NM_130837.2:c.33-9152C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.446,0.0015,1KG_AFR_AF,OPA1
607126,3:193323366:A>G,NM_130837.2:c.33-9146A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.374,0.001,1KG_EAS_AF,OPA1
607127,3:193323371:G>C,NM_130837.2:c.33-9141G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.706,\N,\N,OPA1
607128,3:193323373:G>A,NM_130837.2:c.33-9139G>A,\N,\N,1/30,Benign,\N,intron_variant,0.08,0.0234,1KG_AFR_AF,OPA1
607129,3:193323388:G>A,NM_130837.2:c.33-9124G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,4.264,\N,\N,OPA1
607130,3:193323400:T>C,NM_130837.2:c.33-9112T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,4.206,\N,\N,OPA1
607131,3:193323441:A>G,NM_130837.2:c.33-9071A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,8.926,\N,\N,OPA1
607132,3:193323480:GA>G,NM_130837.2:c.33-9028del,\N,\N,1/30,Unknown significance,\N,intron_variant,0.977,0.0023,1KG_AFR_AF,OPA1
607133,3:193323521:C>T,NM_130837.2:c.33-8991C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.536,0.001,1KG_SAS_AF,OPA1
607134,3:193323541:C>G,NM_130837.2:c.33-8971C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.008,\N,\N,OPA1
607135,3:193323549:C>T,NM_130837.2:c.33-8963C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.689,0.0008,1KG_AFR_AF,OPA1
607136,3:193323550:G>A,NM_130837.2:c.33-8962G>A,\N,\N,1/30,Benign,\N,intron_variant,1.401,0.0121,1KG_AFR_AF,OPA1
607137,3:193323561:CTG>C,NM_130837.2:c.33-8947_33-8946del,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
607138,3:193323570:TC>T,NM_130837.2:c.33-8941del,\N,\N,1/30,Benign,\N,intron_variant,1.17,0.0257,1KG_AFR_AF,OPA1
607139,3:193323571:C>T,NM_130837.2:c.33-8941C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.473,\N,\N,OPA1
607140,3:193323637:C>A,NM_130837.2:c.33-8875C>A,\N,\N,1/30,Unknown significance,\N,intron_variant,3.493,0.0014,1KG_AMR_AF,OPA1
607141,3:193323660:TTACTC>T,NM_130837.2:c.33-8849_33-8845del,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
607142,3:193323679:G>T,NM_130837.2:c.33-8833G>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.368,\N,\N,OPA1
607143,3:193323735:A>G,NM_130837.2:c.33-8777A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.011,\N,\N,OPA1
607144,3:193323737:A>G,NM_130837.2:c.33-8775A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.68,0.0014,1KG_AMR_AF,OPA1
607145,3:193323769:C>T,NM_130837.2:c.33-8743C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,4.598,0.001,1KG_EAS_AF,OPA1
607146,3:193323773:A>G,NM_130837.2:c.33-8739A>G,\N,\N,1/30,Benign,\N,intron_variant,2.289,0.0099,1KG_EAS_AF,OPA1
607147,3:193323780:T>C,NM_130837.2:c.33-8732T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.835,0.0015,1KG_AFR_AF,OPA1
607148,3:193323842:A>G,NM_130837.2:c.33-8670A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.336,0.001,1KG_SAS_AF,OPA1
607149,3:193323879:G>A,NM_130837.2:c.33-8633G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,2.784,0.001,1KG_EAS_AF,OPA1
607150,3:193323904:G>A,NM_130837.2:c.33-8608G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.894,0.0008,1KG_AFR_AF,OPA1
607151,3:193323917:C>T,NM_130837.2:c.33-8595C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.918,\N,\N,OPA1
607152,3:193323928:T>A,NM_130837.2:c.33-8584T>A,\N,\N,1/30,Unknown significance,\N,intron_variant,8.318,0.0015,1KG_AFR_AF,OPA1
607153,3:193323952:A>G,NM_130837.2:c.33-8560A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,3.99,0.001,1KG_SAS_AF,OPA1
607154,3:193324006:G>T,NM_130837.2:c.33-8506G>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.761,\N,\N,OPA1
607155,3:193324007:A>AT,NM_130837.2:c.33-8498dup,\N,\N,1/30,Unknown significance,\N,intron_variant,0.086,\N,\N,OPA1
607156,3:193324007:A>G,NM_130837.2:c.33-8505A>G,\N,\N,1/30,Benign,\N,intron_variant,1.632,0.0068,1KG_AFR_AF,OPA1
607157,3:193324056:A>G,NM_130837.2:c.33-8456A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.025,0.001,1KG_EAS_AF,OPA1
607158,3:193324059:A>AT,NM_130837.2:c.33-8444dup,\N,\N,1/30,Unknown significance,\N,intron_variant,0.012,\N,\N,OPA1
607159,3:193324059:A>T,NM_130837.2:c.33-8453A>T,\N,\N,1/30,Benign,\N,intron_variant,0.004,0.0358,1KG_EUR_AF,OPA1
607160,3:193324060:T>A,NM_130837.2:c.33-8452T>A,\N,\N,1/30,Benign,\N,intron_variant,4.471,0.0072,1KG_SAS_AF,OPA1
607161,3:193324093:A>G,NM_130837.2:c.33-8419A>G,\N,\N,1/30,Benign,\N,intron_variant,1.204,0.0099,1KG_EAS_AF,OPA1
607162,3:193324103:C>T,NM_130837.2:c.33-8409C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,4.193,\N,\N,OPA1
607163,3:193324113:T>A,NM_130837.2:c.33-8399T>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.902,\N,\N,OPA1
607164,3:193324119:A>G,NM_130837.2:c.33-8393A>G,\N,\N,1/30,Benign,\N,intron_variant,0.55,0.0179,1KG_EAS_AF,OPA1
607165,3:193324174:T>C,NM_130837.2:c.33-8338T>C,\N,\N,1/30,Benign,\N,intron_variant,1.376,0.0184,1KG_SAS_AF,OPA1
607166,3:193324203:C>T,NM_130837.2:c.33-8309C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.876,0.0014,1KG_AMR_AF,OPA1
607167,3:193324258:A>G,NM_130837.2:c.33-8254A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,3.296,0.0029,1KG_AMR_AF,OPA1
607168,3:193324275:A>C,NM_130837.2:c.33-8237A>C,\N,\N,1/30,Benign,\N,intron_variant,0.109,0.4463,1KG_AFR_AF,OPA1
607169,3:193324301:C>T,NM_130837.2:c.33-8211C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.454,0.0023,1KG_AFR_AF,OPA1
607170,3:193324324:T>C,NM_130837.2:c.33-8188T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.024,\N,\N,OPA1
607171,3:193324373:A>G,NM_130837.2:c.33-8139A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.773,0.0014,1KG_AMR_AF,OPA1
607172,3:193324399:G>T,NM_130837.2:c.33-8113G>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.155,\N,\N,OPA1
607173,3:193324412:T>TC,NM_130837.2:c.33-8098dup,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
607174,3:193324422:A>G,NM_130837.2:c.33-8090A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.565,0.001,1KG_SAS_AF,OPA1
607175,3:193324426:A>G,NM_130837.2:c.33-8086A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.438,\N,\N,OPA1
607176,3:193324469:T>G,NM_130837.2:c.33-8043T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.329,\N,\N,OPA1
607177,3:193324475:T>A,NM_130837.2:c.33-8037T>A,\N,\N,1/30,Unknown significance,\N,intron_variant,4.487,\N,\N,OPA1
607178,3:193324603:T>A,NM_130837.2:c.33-7909T>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.086,0.001,1KG_EUR_AF,OPA1
607179,3:193324866:G>A,NM_130837.2:c.33-7646G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.466,0.001,1KG_SAS_AF,OPA1
607180,3:193324874:A>C,NM_130837.2:c.33-7638A>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.899,\N,\N,OPA1
607181,3:193324876:A>G,NM_130837.2:c.33-7636A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.633,0.0008,1KG_AFR_AF,OPA1
607182,3:193324891:G>T,NM_130837.2:c.33-7621G>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.144,0.0008,1KG_AFR_AF,OPA1
607183,3:193324928:T>G,NM_130837.2:c.33-7584T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.554,0.0014,1KG_AMR_AF,OPA1
607184,3:193324965:C>G,NM_130837.2:c.33-7547C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.102,0.001,1KG_SAS_AF,OPA1
607185,3:193324993:C>G,NM_130837.2:c.33-7519C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,6.942,\N,\N,OPA1
607186,3:193324996:T>G,NM_130837.2:c.33-7516T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,9.413,0.0014,1KG_AMR_AF,OPA1
607187,3:193324997:C>T,NM_130837.2:c.33-7515C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,8.868,0.0014,1KG_AMR_AF,OPA1
607188,3:193325115:C>T,NM_130837.2:c.33-7397C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,4.976,0.001,1KG_EUR_AF,OPA1
607189,3:193325128:G>C,NM_130837.2:c.33-7384G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.315,\N,\N,OPA1
607190,3:193325170:A>G,NM_130837.2:c.33-7342A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,5.378,0.0014,1KG_AMR_AF,OPA1
607191,3:193325224:T>A,NM_130837.2:c.33-7288T>A,\N,\N,1/30,Benign,\N,intron_variant,12.24,0.0208,1KG_EAS_AF,OPA1
607192,3:193325228:G>A,NM_130837.2:c.33-7284G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,9.822,\N,\N,OPA1
607193,3:193325253:G>A,NM_130837.2:c.33-7259G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,10.13,0.0015,1KG_AFR_AF,OPA1
607194,3:193325269:T>G,NM_130837.2:c.33-7243T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,10.61,0.0008,1KG_AFR_AF,OPA1
607195,3:193325307:G>C,NM_130837.2:c.33-7205G>C,\N,\N,1/30,Benign,\N,intron_variant,5.185,0.0477,1KG_AFR_AF,OPA1
607196,3:193325323:T>C,NM_130837.2:c.33-7189T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.519,0.003,1KG_EUR_AF,OPA1
607197,3:193325335:G>C,NM_130837.2:c.33-7177G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.959,0.0015,1KG_AFR_AF,OPA1
607198,3:193325367:T>C,NM_130837.2:c.33-7145T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.934,0.0029,1KG_AMR_AF,OPA1
607199,3:193325369:T>C,NM_130837.2:c.33-7143T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.632,0.0014,1KG_AMR_AF,OPA1
607200,3:193325372:G>A,NM_130837.2:c.33-7140G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.213,\N,\N,OPA1
607201,3:193325403:A>C,NM_130837.2:c.33-7109A>C,\N,\N,1/30,Unknown significance,\N,intron_variant,3.963,0.001,1KG_EUR_AF,OPA1
607202,3:193325413:A>G,NM_130837.2:c.33-7099A>G,\N,\N,1/30,Benign,\N,intron_variant,3.879,0.0061,1KG_SAS_AF,OPA1
607203,3:193325444:T>C,NM_130837.2:c.33-7068T>C,\N,\N,1/30,Benign,\N,intron_variant,5.502,0.0099,1KG_EUR_AF,OPA1
607204,3:193325447:G>A,NM_130837.2:c.33-7065G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,4.088,\N,\N,OPA1
607205,3:193325455:A>T,NM_130837.2:c.33-7057A>T,\N,\N,1/30,Unknown significance,\N,intron_variant,5.394,0.0008,1KG_AFR_AF,OPA1
607206,3:193325464:T>C,NM_130837.2:c.33-7048T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,5.562,0.001,1KG_EUR_AF,OPA1
607207,3:193325466:G>A,NM_130837.2:c.33-7046G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,6.442,0.001,1KG_EAS_AF,OPA1
607208,3:193325482:C>T,NM_130837.2:c.33-7030C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.862,\N,\N,OPA1
607209,3:193325513:G>C,NM_130837.2:c.33-6999G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.897,\N,\N,OPA1
607210,3:193325545:T>C,NM_130837.2:c.33-6967T>C,\N,\N,1/30,Benign,\N,intron_variant,3.993,0.4254,1KG_EUR_AF,OPA1
607211,3:193325551:A>G,NM_130837.2:c.33-6961A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.753,0.002,1KG_EAS_AF,OPA1
607212,3:193325579:C>G,NM_130837.2:c.33-6933C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,3.274,0.001,1KG_EUR_AF,OPA1
607213,3:193325613:G>A,NM_130837.2:c.33-6899G>A,\N,\N,1/30,Benign,\N,intron_variant,10.28,0.007,1KG_EUR_AF,OPA1
607214,3:193325633:C>G,NM_130837.2:c.33-6879C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,10.33,0.0023,1KG_AFR_AF,OPA1
607215,3:193325684:A>G,NM_130837.2:c.33-6828A>G,\N,\N,1/30,Benign,\N,intron_variant,10.19,0.0069,1KG_EAS_AF,OPA1
607216,3:193325688:A>C,NM_130837.2:c.33-6824A>C,\N,\N,1/30,Unknown significance,\N,intron_variant,8.392,0.001,1KG_SAS_AF,OPA1
607217,3:193325703:G>C,NM_130837.2:c.33-6809G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,4.763,0.0008,1KG_AFR_AF,OPA1
607218,3:193325745:C>A,NM_130837.2:c.33-6767C>A,\N,\N,1/30,Benign,\N,intron_variant,2.067,0.0169,1KG_EAS_AF,OPA1
607219,3:193325776:T>A,NM_130837.2:c.33-6736T>A,\N,\N,1/30,Unknown significance,\N,intron_variant,3.235,\N,\N,OPA1
607220,3:193325820:T>C,NM_130837.2:c.33-6692T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.748,\N,\N,OPA1
607221,3:193325822:A>G,NM_130837.2:c.33-6690A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.291,\N,\N,OPA1
607222,3:193325823:G>C,NM_130837.2:c.33-6689G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.371,0.002,1KG_EAS_AF,OPA1
607223,3:193325846:CTGTT>C,NM_130837.2:c.33-6662_33-6659del,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
607224,3:193325847:T>C,NM_130837.2:c.33-6665T>C,\N,\N,1/30,Benign,\N,intron_variant,0.828,0.0058,1KG_AMR_AF,OPA1
607225,3:193325870:A>G,NM_130837.2:c.33-6642A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.146,\N,\N,OPA1
607226,3:193325906:C>T,NM_130837.2:c.33-6606C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.822,\N,\N,OPA1
607227,3:193325907:G>A,NM_130837.2:c.33-6605G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.844,0.0041,1KG_SAS_AF,OPA1
607228,3:193325920:T>G,NM_130837.2:c.33-6592T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.949,\N,\N,OPA1
607229,3:193325926:T>A,NM_130837.2:c.33-6586T>A,\N,\N,1/30,Benign,\N,intron_variant,4.681,0.0424,1KG_AFR_AF,OPA1
607230,3:193325946:C>G,NM_130837.2:c.33-6566C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.694,\N,\N,OPA1
607231,3:193326023:C>A,NM_130837.2:c.33-6489C>A,\N,\N,1/30,Unknown significance,\N,intron_variant,2.481,0.001,1KG_SAS_AF,OPA1
607232,3:193326025:T>C,NM_130837.2:c.33-6487T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.109,0.001,1KG_EAS_AF,OPA1
607233,3:193326052:C>A,NM_130837.2:c.33-6460C>A,\N,\N,1/30,Unknown significance,\N,intron_variant,7.161,0.001,1KG_EUR_AF,OPA1
607234,3:193326072:A>G,NM_130837.2:c.33-6440A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,4.59,\N,\N,OPA1
607235,3:193326092:A>C,NM_130837.2:c.33-6420A>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.366,0.0015,1KG_AFR_AF,OPA1
607236,3:193326093:A>G,NM_130837.2:c.33-6419A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,3.352,0.003,1KG_EAS_AF,OPA1
607237,3:193326132:G>A,NM_130837.2:c.33-6380G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,5.01,0.0014,1KG_AMR_AF,OPA1
607238,3:193326137:A>G,NM_130837.2:c.33-6375A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,4.111,0.001,1KG_EUR_AF,OPA1
607239,3:193326161:G>A,NM_130837.2:c.33-6351G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,6.52,\N,\N,OPA1
607240,3:193326245:A>G,NM_130837.2:c.33-6267A>G,\N,\N,1/30,Benign,\N,intron_variant,7.276,0.0121,1KG_AFR_AF,OPA1
607241,3:193326282:T>G,NM_130837.2:c.33-6230T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.225,0.001,1KG_EAS_AF,OPA1
607242,3:193326298:A>G,NM_130837.2:c.33-6214A>G,\N,\N,1/30,Benign,\N,intron_variant,0.111,0.4284,1KG_EUR_AF,OPA1
607243,3:193326339:C>G,NM_130837.2:c.33-6173C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.076,\N,\N,OPA1
607244,3:193326363:G>C,NM_130837.2:c.33-6149G>C,\N,\N,1/30,Benign,\N,intron_variant,0.017,0.0121,1KG_AFR_AF,OPA1
607245,3:193326419:G>T,NM_130837.2:c.33-6093G>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.751,0.0008,1KG_AFR_AF,OPA1
607246,3:193326437:G>T,NM_130837.2:c.33-6075G>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.315,\N,\N,OPA1
607247,3:193326441:T>C,NM_130837.2:c.33-6071T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,2.308,0.001,1KG_EAS_AF,OPA1
607248,3:193326458:C>T,NM_130837.2:c.33-6054C>T,\N,\N,1/30,Benign,\N,intron_variant,2.089,0.5847,1KG_AFR_AF,OPA1
607249,3:193326564:G>A,NM_130837.2:c.33-5948G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,5.79,0.0029,1KG_AMR_AF,OPA1
607250,3:193326568:G>A,NM_130837.2:c.33-5944G>A,\N,\N,1/30,Benign,\N,intron_variant,0.85,0.0961,1KG_AFR_AF,OPA1
607251,3:193326602:T>C,NM_130837.2:c.33-5910T>C,\N,\N,1/30,Benign,\N,intron_variant,4.698,0.0053,1KG_AFR_AF,OPA1
607252,3:193326651:G>A,NM_130837.2:c.33-5861G>A,\N,\N,1/30,Benign,\N,intron_variant,0.965,0.5847,1KG_AFR_AF,OPA1
607253,3:193326668:G>A,NM_130837.2:c.33-5844G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,2.774,0.0014,1KG_AMR_AF,OPA1
607254,3:193326678:G>C,NM_130837.2:c.33-5834G>C,\N,\N,1/30,Benign,\N,intron_variant,0.99,0.0051,1KG_SAS_AF,OPA1
607255,3:193326680:A>G,NM_130837.2:c.33-5832A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,3.566,\N,\N,OPA1
607256,3:193326685:T>A,NM_130837.2:c.33-5827T>A,\N,\N,1/30,Benign,\N,intron_variant,6.073,0.0367,1KG_EAS_AF,OPA1
607257,3:193326725:T>G,NM_130837.2:c.33-5787T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,8.015,0.0015,1KG_AFR_AF,OPA1
607258,3:193326736:C>G,NM_130837.2:c.33-5776C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,7.757,0.001,1KG_SAS_AF,OPA1
607259,3:193326749:G>A,NM_130837.2:c.33-5763G>A,\N,\N,1/30,Benign,\N,intron_variant,9.469,0.0053,1KG_AFR_AF,OPA1
607260,3:193326783:A>T,NM_130837.2:c.33-5729A>T,\N,\N,1/30,Unknown significance,\N,intron_variant,7.098,0.0015,1KG_AFR_AF,OPA1
607261,3:193326787:CTGTT>C,NM_130837.2:c.33-5723_33-5720del,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
607262,3:193326845:G>T,NM_130837.2:c.33-5667G>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.378,0.001,1KG_EUR_AF,OPA1
607263,3:193326847:A>G,NM_130837.2:c.33-5665A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.063,\N,\N,OPA1
607264,3:193326885:A>T,NM_130837.2:c.33-5627A>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.052,\N,\N,OPA1
607265,3:193326888:C>T,NM_130837.2:c.33-5624C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.234,\N,\N,OPA1
607266,3:193326893:C>T,NM_130837.2:c.33-5619C>T,\N,\N,1/30,Benign,\N,intron_variant,0.082,0.1059,1KG_AFR_AF,OPA1
607267,3:193326894:G>C,NM_130837.2:c.33-5618G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.091,\N,\N,OPA1
607268,3:193326896:G>T,NM_130837.2:c.33-5616G>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.364,\N,\N,OPA1
607269,3:193326899:A>G,NM_130837.2:c.33-5613A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.838,\N,\N,OPA1
607270,3:193326936:C>G,NM_130837.2:c.33-5576C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.498,0.002,1KG_SAS_AF,OPA1
607271,3:193326958:C>T,NM_130837.2:c.33-5554C>T,\N,\N,1/30,Benign,\N,intron_variant,1.342,0.0053,1KG_AFR_AF,OPA1
607272,3:193326985:C>A,NM_130837.2:c.33-5527C>A,\N,\N,1/30,Unknown significance,\N,intron_variant,6.483,\N,\N,OPA1
607273,3:193327006:T>C,NM_130837.2:c.33-5506T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,6.096,0.003,1KG_EAS_AF,OPA1
607274,3:193327018:A>G,NM_130837.2:c.33-5494A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,7.967,0.0008,1KG_AFR_AF,OPA1
607275,3:193327066:T>A,NM_130837.2:c.33-5446T>A,\N,\N,1/30,Unknown significance,\N,intron_variant,8.51,0.0014,1KG_AMR_AF,OPA1
607276,3:193327067:A>G,NM_130837.2:c.33-5445A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,7.413,\N,\N,OPA1
607277,3:193327116:G>C,NM_130837.2:c.33-5396G>C,\N,\N,1/30,Benign,\N,intron_variant,0.154,0.0121,1KG_AFR_AF,OPA1
607278,3:193327123:A>T,NM_130837.2:c.33-5389A>T,\N,\N,1/30,Benign,\N,intron_variant,0.29,0.006,1KG_EUR_AF,OPA1
607279,3:193327134:T>C,NM_130837.2:c.33-5378T>C,\N,\N,1/30,Benign,\N,intron_variant,0.957,0.0179,1KG_EAS_AF,OPA1
607280,3:193327186:C>T,NM_130837.2:c.33-5326C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.006,0.001,1KG_SAS_AF,OPA1
607281,3:193327187:G>A,NM_130837.2:c.33-5325G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.227,0.001,1KG_EAS_AF,OPA1
607282,3:193327202:G>A,NM_130837.2:c.33-5310G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.157,0.0008,1KG_AFR_AF,OPA1
607283,3:193327222:G>A,NM_130837.2:c.33-5290G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.416,0.0014,1KG_AMR_AF,OPA1
607284,3:193327231:C>A,NM_130837.2:c.33-5281C>A,\N,\N,1/30,Unknown significance,\N,intron_variant,2.72,0.001,1KG_EAS_AF,OPA1
607285,3:193327253:A>G,NM_130837.2:c.33-5259A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.229,0.0038,1KG_AFR_AF,OPA1
607286,3:193327282:G>A,NM_130837.2:c.33-5230G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,7.173,0.0008,1KG_AFR_AF,OPA1
607287,3:193327303:T>C,NM_130837.2:c.33-5209T>C,\N,\N,1/30,Benign,\N,intron_variant,3.971,0.0053,1KG_AFR_AF,OPA1
607288,3:193327335:G>A,NM_130837.2:c.33-5177G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.718,0.002,1KG_EAS_AF,OPA1
607289,3:193327345:C>CT,NM_130837.2:c.33-5166dup,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
607290,3:193327352:T>C,NM_130837.2:c.33-5160T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.74,\N,\N,OPA1
607291,3:193327358:AT>A,NM_130837.2:c.33-5151del,\N,\N,1/30,Benign,\N,intron_variant,0.31,0.0204,1KG_AFR_AF,OPA1
607292,3:193327379:G>C,NM_130837.2:c.33-5133G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.335,\N,\N,OPA1
607293,3:193327402:G>A,NM_130837.2:c.33-5110G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,3.034,0.001,1KG_EAS_AF,OPA1
607294,3:193327437:C>G,NM_130837.2:c.33-5075C>G,\N,\N,1/30,Benign,\N,intron_variant,1.015,0.0182,1KG_AFR_AF,OPA1
607295,3:193327472:C>T,NM_130837.2:c.33-5040C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,3.078,\N,\N,OPA1
607296,3:193327507:T>C,NM_130837.2:c.33-5005T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,6.352,0.0031,1KG_SAS_AF,OPA1
607297,3:193327521:C>T,NM_130837.2:c.33-4991C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,5.138,0.0015,1KG_AFR_AF,OPA1
607298,3:193327525:T>C,NM_130837.2:c.33-4987T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,4.662,0.001,1KG_EUR_AF,OPA1
607299,3:193327540:T>G,NM_130837.2:c.33-4972T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,5.119,0.0008,1KG_AFR_AF,OPA1
607300,3:193327556:TC>T,NM_130837.2:c.33-4953del,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
607301,3:193327559:C>T,NM_130837.2:c.33-4953C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.12,0.002,1KG_EAS_AF,OPA1
607302,3:193327560:G>A,NM_130837.2:c.33-4952G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.217,\N,\N,OPA1
607303,3:193327619:C>A,NM_130837.2:c.33-4893C>A,\N,\N,1/30,Benign,\N,intron_variant,3.07,0.0367,1KG_EAS_AF,OPA1
607304,3:193327647:G>A,NM_130837.2:c.33-4865G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.477,\N,\N,OPA1
607305,3:193327661:T>A,NM_130837.2:c.33-4851T>A,\N,\N,1/30,Unknown significance,\N,intron_variant,6.035,\N,\N,OPA1
607306,3:193327694:T>C,NM_130837.2:c.33-4818T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,6.203,0.001,1KG_SAS_AF,OPA1
607307,3:193327722:G>GTTCGTCGAATTTTT,NM_130837.2:c.33-4786_33-4773dup,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
607308,3:193327722:GTTCGTCGAATTTTT>G,NM_130837.2:c.33-4786_33-4773del,\N,\N,1/30,Benign,\N,intron_variant,1.65,0.4284,1KG_EUR_AF,OPA1
607309,3:193327725:C>T,NM_130837.2:c.33-4787C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.2,0.001,1KG_EUR_AF,OPA1
607310,3:193327728:C>T,NM_130837.2:c.33-4784C>T,\N,\N,1/30,Benign,\N,intron_variant,2.584,0.0173,1KG_AMR_AF,OPA1
607311,3:193327736:T>G,NM_130837.2:c.33-4776T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.42,\N,\N,OPA1
607312,3:193327806:A>C,NM_130837.2:c.33-4706A>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.556,\N,\N,OPA1
607313,3:193327806:A>T,NM_130837.2:c.33-4706A>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.048,\N,\N,OPA1
607314,3:193327809:T>C,NM_130837.2:c.33-4703T>C,\N,\N,1/30,Benign,\N,intron_variant,0.793,0.4597,1KG_AMR_AF,OPA1
607315,3:193327826:G>A,NM_130837.2:c.33-4686G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.887,0,1KG_ALL_AF|1KG_AFR_AF|1KG_AMR_AF|1KG_EAS_AF|1KG_EUR_AF|1KG_SAS_AF,OPA1
607316,3:193327857:G>A,NM_130837.2:c.33-4655G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.063,0.0015,1KG_AFR_AF,OPA1
607317,3:193327937:C>T,NM_130837.2:c.33-4575C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.105,0.0014,1KG_AMR_AF,OPA1
607318,3:193327958:G>A,NM_130837.2:c.33-4554G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.112,0.001,1KG_SAS_AF,OPA1
607319,3:193327977:TGATG>T,NM_130837.2:c.33-4533_33-4530del,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
607320,3:193328068:A>G,NM_130837.2:c.33-4444A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,7.829,0.0008,1KG_AFR_AF,OPA1
607321,3:193328121:C>T,NM_130837.2:c.33-4391C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,4.489,0.002,1KG_EAS_AF,OPA1
607322,3:193328136:A>G,NM_130837.2:c.33-4376A>G,\N,\N,1/30,Benign,\N,intron_variant,0.076,0.0179,1KG_EAS_AF,OPA1
607323,3:193328137:A>G,NM_130837.2:c.33-4375A>G,\N,\N,1/30,Benign,\N,intron_variant,1.927,0.8354,1KG_SAS_AF,OPA1
607324,3:193328139:G>A,NM_130837.2:c.33-4373G>A,\N,\N,1/30,Benign,\N,intron_variant,1.186,0.0613,1KG_AFR_AF,OPA1
607325,3:193328142:T>C,NM_130837.2:c.33-4370T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.762,\N,\N,OPA1
607326,3:193328143:A>G,NM_130837.2:c.33-4369A>G,\N,\N,1/30,Benign,\N,intron_variant,1.357,0.0219,1KG_AFR_AF,OPA1
607327,3:193328207:C>T,NM_130837.2:c.33-4305C>T,\N,\N,1/30,Benign,\N,intron_variant,0.111,0.0069,1KG_EAS_AF,OPA1
607328,3:193328212:A>G,NM_130837.2:c.33-4300A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.991,\N,\N,OPA1
607329,3:193328221:G>A,NM_130837.2:c.33-4291G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,3.203,\N,\N,OPA1
607330,3:193328235:A>G,NM_130837.2:c.33-4277A>G,\N,\N,1/30,Benign,\N,intron_variant,3.821,0.1051,1KG_AFR_AF,OPA1
607331,3:193328237:T>TG,NM_130837.2:c.33-4269dup,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
607332,3:193328245:GCCTCC>G,NM_130837.2:c.33-4265_33-4261del,\N,\N,1/30,Benign,\N,intron_variant,1.615,0.0159,1KG_AFR_AF,OPA1
607333,3:193328261:A>G,NM_130837.2:c.33-4251A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.219,0.0023,1KG_AFR_AF,OPA1
607334,3:193328264:C>T,NM_130837.2:c.33-4248C>T,\N,\N,1/30,Benign,\N,intron_variant,2.428,0.0113,1KG_AFR_AF,OPA1
607335,3:193328265:G>A,NM_130837.2:c.33-4247G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.971,0.002,1KG_EUR_AF,OPA1
607336,3:193328332:AC>A,NM_130837.2:c.33-4178del,\N,\N,1/30,Unknown significance,\N,intron_variant,0.924,0.0023,1KG_AFR_AF,OPA1
607337,3:193328397:T>G,NM_130837.2:c.33-4115T>G,\N,\N,1/30,Benign,\N,intron_variant,7.254,0.0069,1KG_EAS_AF,OPA1
607338,3:193328401:C>T,NM_130837.2:c.33-4111C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,6.274,\N,\N,OPA1
607339,3:193328406:A>G,NM_130837.2:c.33-4106A>G,\N,\N,1/30,Benign,\N,intron_variant,5.569,0.0121,1KG_AFR_AF,OPA1
607340,3:193328416:T>C,NM_130837.2:c.33-4096T>C,\N,\N,1/30,Benign,\N,intron_variant,1.696,0.5847,1KG_AFR_AF,OPA1
607341,3:193328417:G>A,NM_130837.2:c.33-4095G>A,\N,\N,1/30,Benign,\N,intron_variant,0.189,0.0072,1KG_AMR_AF,OPA1
607342,3:193328420:G>C,NM_130837.2:c.33-4092G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.347,\N,\N,OPA1
607343,3:193328438:G>A,NM_130837.2:c.33-4074G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.757,0.0008,1KG_AFR_AF,OPA1
607344,3:193328444:A>C,NM_130837.2:c.33-4068A>C,\N,\N,1/30,Benign,\N,intron_variant,0.886,0.0112,1KG_SAS_AF,OPA1
607345,3:193328498:T>G,NM_130837.2:c.33-4014T>G,\N,\N,1/30,Benign,\N,intron_variant,0.765,0.5847,1KG_AFR_AF,OPA1
607346,3:193328502:A>G,NM_130837.2:c.33-4010A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.183,\N,\N,OPA1
607347,3:193328517:C>T,NM_130837.2:c.33-3995C>T,\N,\N,1/30,Benign,\N,intron_variant,1.322,0.0121,1KG_AFR_AF,OPA1
607348,3:193328518:G>C,NM_130837.2:c.33-3994G>C,\N,\N,1/30,Benign,\N,intron_variant,0.252,0.0089,1KG_EUR_AF,OPA1
607349,3:193328533:C>T,NM_130837.2:c.33-3979C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.908,\N,\N,OPA1
607350,3:193328540:C>T,NM_130837.2:c.33-3972C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.391,0.0008,1KG_AFR_AF,OPA1
607351,3:193328547:G>A,NM_130837.2:c.33-3965G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.154,0.002,1KG_EAS_AF,OPA1
607352,3:193328567:T>C,NM_130837.2:c.33-3945T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,6.093,0.001,1KG_EUR_AF,OPA1
607353,3:193328589:T>C,NM_130837.2:c.33-3923T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,5.433,\N,\N,OPA1
607354,3:193328593:C>T,NM_130837.2:c.33-3919C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,4.557,0.001,1KG_EUR_AF,OPA1
607355,3:193328612:G>A,NM_130837.2:c.33-3900G>A,\N,\N,1/30,Benign,\N,intron_variant,3.421,0.0325,1KG_AFR_AF,OPA1
607356,3:193328630:C>T,NM_130837.2:c.33-3882C>T,\N,\N,1/30,Benign,\N,intron_variant,1.675,0.0179,1KG_EAS_AF,OPA1
607357,3:193328631:G>A,NM_130837.2:c.33-3881G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.726,\N,\N,OPA1
607358,3:193328633:GAT>G,NM_130837.2:c.33-3875_33-3874del,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
607359,3:193328645:T>C,NM_130837.2:c.33-3867T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,2.1,0.002,1KG_EUR_AF,OPA1
607360,3:193328654:G>A,NM_130837.2:c.33-3858G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.288,0.0008,1KG_AFR_AF,OPA1
607361,3:193328670:G>A,NM_130837.2:c.33-3842G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.115,\N,\N,OPA1
607362,3:193328677:C>T,NM_130837.2:c.33-3835C>T,\N,\N,1/30,Benign,\N,intron_variant,0.269,0.0258,1KG_EUR_AF,OPA1
607363,3:193328678:G>A,NM_130837.2:c.33-3834G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.849,\N,\N,OPA1
607364,3:193328708:C>T,NM_130837.2:c.33-3804C>T,\N,\N,1/30,Benign,\N,intron_variant,3.623,0.0469,1KG_AFR_AF,OPA1
607365,3:193328714:G>T,NM_130837.2:c.33-3798G>T,\N,\N,1/30,Benign,\N,intron_variant,0.839,0.0456,1KG_EAS_AF,OPA1
607366,3:193328725:C>T,NM_130837.2:c.33-3787C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,3.191,0.003,1KG_EUR_AF,OPA1
607367,3:193328726:C>T,NM_130837.2:c.33-3786C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.883,0.0014,1KG_AMR_AF,OPA1
607368,3:193328741:G>A,NM_130837.2:c.33-3771G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,3.135,0.001,1KG_EUR_AF,OPA1
607369,3:193328742:G>C,NM_130837.2:c.33-3770G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.607,\N,\N,OPA1
607370,3:193328756:T>C,NM_130837.2:c.33-3756T>C,\N,\N,1/30,Benign,\N,intron_variant,2.063,0.0198,1KG_EAS_AF,OPA1
607371,3:193328773:T>A,NM_130837.2:c.33-3739T>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.745,0.002,1KG_EUR_AF,OPA1
607372,3:193328775:G>A,NM_130837.2:c.33-3737G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,2.037,\N,\N,OPA1
607373,3:193328783:G>T,NM_130837.2:c.33-3729G>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.638,\N,\N,OPA1
607374,3:193328790:C>T,NM_130837.2:c.33-3722C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.152,0.001,1KG_SAS_AF,OPA1
607375,3:193328811:C>T,NM_130837.2:c.33-3701C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.125,\N,\N,OPA1
607376,3:193328812:G>A,NM_130837.2:c.33-3700G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.055,0.0023,1KG_AFR_AF,OPA1
607377,3:193328817:G>C,NM_130837.2:c.33-3695G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.153,\N,\N,OPA1
607378,3:193328820:G>A,NM_130837.2:c.33-3692G>A,\N,\N,1/30,Benign,\N,intron_variant,1.534,0.0053,1KG_AFR_AF,OPA1
607379,3:193328823:C>T,NM_130837.2:c.33-3689C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.908,0.001,1KG_EAS_AF,OPA1
607380,3:193328875:C>T,NM_130837.2:c.33-3637C>T,\N,\N,1/30,Benign,\N,intron_variant,4.417,0.0072,1KG_SAS_AF,OPA1
607381,3:193328884:G>A,NM_130837.2:c.33-3628G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,2.593,0.001,1KG_EUR_AF,OPA1
607382,3:193328895:A>G,NM_130837.2:c.33-3617A>G,\N,\N,1/30,Benign,\N,intron_variant,2.589,0.4284,1KG_EUR_AF,OPA1
607383,3:193328900:C>A,NM_130837.2:c.33-3612C>A,\N,\N,1/30,Benign,\N,intron_variant,3.045,0.0144,1KG_AFR_AF,OPA1
607384,3:193328902:G>A,NM_130837.2:c.33-3610G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.104,0.0008,1KG_AFR_AF,OPA1
607385,3:193328905:T>G,NM_130837.2:c.33-3607T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.69,\N,\N,OPA1
607386,3:193328910:C>T,NM_130837.2:c.33-3602C>T,\N,\N,1/30,Benign,\N,intron_variant,1.315,0.0121,1KG_AFR_AF,OPA1
607387,3:193328939:A>C,NM_130837.2:c.33-3573A>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.269,0.0014,1KG_AMR_AF,OPA1
607388,3:193328962:G>A,NM_130837.2:c.33-3550G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,2.138,0.0014,1KG_AMR_AF,OPA1
607389,3:193328968:G>A,NM_130837.2:c.33-3544G>A,\N,\N,1/30,Benign,\N,intron_variant,1.738,0.0437,1KG_EAS_AF,OPA1
607390,3:193328971:C>T,NM_130837.2:c.33-3541C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.269,0.0038,1KG_AFR_AF,OPA1
607391,3:193328990:G>A,NM_130837.2:c.33-3522G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.883,\N,\N,OPA1
607392,3:193328994:G>A,NM_130837.2:c.33-3518G>A,\N,\N,1/30,Benign,\N,intron_variant,0.067,0.0115,1KG_AMR_AF,OPA1
607393,3:193329022:G>A,NM_130837.2:c.33-3490G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,3.516,0.001,1KG_EUR_AF,OPA1
607394,3:193329034:A>G,NM_130837.2:c.33-3478A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.126,\N,\N,OPA1
607395,3:193329059:C>T,NM_130837.2:c.33-3453C>T,\N,\N,1/30,Benign,\N,intron_variant,0.672,0.0101,1KG_AMR_AF,OPA1
607396,3:193329086:CT>C,NM_130837.2:c.33-3424del,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
607397,3:193329112:G>C,NM_130837.2:c.33-3400G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.304,0.003,1KG_EUR_AF,OPA1
607398,3:193329115:C>T,NM_130837.2:c.33-3397C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.487,0.0014,1KG_AMR_AF,OPA1
607399,3:193329125:C>T,NM_130837.2:c.33-3387C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.188,0.001,1KG_EAS_AF,OPA1
607400,3:193329156:G>A,NM_130837.2:c.33-3356G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,2.315,\N,\N,OPA1
607401,3:193329165:A>T,NM_130837.2:c.33-3347A>T,\N,\N,1/30,Benign,\N,intron_variant,0.866,0.0234,1KG_AFR_AF,OPA1
607402,3:193329215:A>T,NM_130837.2:c.33-3297A>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.064,\N,\N,OPA1
607403,3:193329233:C>G,NM_130837.2:c.33-3279C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.143,\N,\N,OPA1
607404,3:193329247:A>C,NM_130837.2:c.33-3265A>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.027,0.0045,1KG_AFR_AF,OPA1
607405,3:193329259:G>A,NM_130837.2:c.33-3253G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.864,\N,\N,OPA1
607406,3:193329268:C>T,NM_130837.2:c.33-3244C>T,\N,\N,1/30,Benign,\N,intron_variant,2.052,0.1051,1KG_AFR_AF,OPA1
607407,3:193329269:G>A,NM_130837.2:c.33-3243G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.358,\N,\N,OPA1
607408,3:193329278:C>G,NM_130837.2:c.33-3234C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.045,\N,\N,OPA1
607409,3:193329279:G>A,NM_130837.2:c.33-3233G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.328,0.0014,1KG_AMR_AF,OPA1
607410,3:193329280:G>A,NM_130837.2:c.33-3232G>A,\N,\N,1/30,Benign,\N,intron_variant,2.275,0.0053,1KG_AFR_AF,OPA1
607411,3:193329300:T>C,NM_130837.2:c.33-3212T>C,\N,\N,1/30,Benign,\N,intron_variant,0.045,0.6172,1KG_AFR_AF,OPA1
607412,3:193329313:G>A,NM_130837.2:c.33-3199G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,2.047,\N,\N,OPA1
607413,3:193329318:A>G,NM_130837.2:c.33-3194A>G,\N,\N,1/30,Benign,\N,intron_variant,0.098,0.5847,1KG_AFR_AF,OPA1
607414,3:193329321:G>A,NM_130837.2:c.33-3191G>A,\N,\N,1/30,Benign,\N,intron_variant,0.667,0.0144,1KG_AFR_AF,OPA1
607415,3:193329342:C>T,NM_130837.2:c.33-3170C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.04,0.0015,1KG_AFR_AF,OPA1
607416,3:193329343:G>A,NM_130837.2:c.33-3169G>A,\N,\N,1/30,Benign,\N,intron_variant,0.326,0.3224,1KG_EAS_AF,OPA1
607417,3:193329355:T>C,NM_130837.2:c.33-3157T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.45,\N,\N,OPA1
607418,3:193329381:A>C,NM_130837.2:c.33-3131A>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.388,\N,\N,OPA1
607419,3:193329385:C>CA,NM_130837.2:c.33-3102dup,\N,\N,1/30,Unknown significance,\N,intron_variant,3.257,\N,\N,OPA1
607420,3:193329385:CA>C,NM_130837.2:c.33-3102del,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
607421,3:193329385:CAA>C,NM_130837.2:c.33-3103_33-3102del,\N,\N,1/30,Unknown significance,\N,intron_variant,4.095,\N,\N,OPA1
607422,3:193329385:CAAA>C,NM_130837.2:c.33-3104_33-3102del,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
607423,3:193329417:C>T,NM_130837.2:c.33-3095C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.628,\N,\N,OPA1
607424,3:193329431:T>G,NM_130837.2:c.33-3081T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,5.232,0.0014,1KG_AMR_AF,OPA1
607425,3:193329434:G>A,NM_130837.2:c.33-3078G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,2.284,\N,\N,OPA1
607426,3:193329443:C>T,NM_130837.2:c.33-3069C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.558,\N,\N,OPA1
607427,3:193329460:C>T,NM_130837.2:c.33-3052C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.292,0.0029,1KG_AMR_AF,OPA1
607428,3:193329506:A>G,NM_130837.2:c.33-3006A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.284,\N,\N,OPA1
607429,3:193329545:A>G,NM_130837.2:c.33-2967A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,8.986,\N,\N,OPA1
607430,3:193329574:A>T,NM_130837.2:c.33-2938A>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.863,\N,\N,OPA1
607431,3:193329591:C>T,NM_130837.2:c.33-2921C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.051,\N,\N,OPA1
607432,3:193329599:C>T,NM_130837.2:c.33-2913C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.451,0.0014,1KG_AMR_AF,OPA1
607433,3:193329604:G>T,NM_130837.2:c.33-2908G>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.537,0.001,1KG_SAS_AF,OPA1
607434,3:193329630:TTTTC>T,NM_130837.2:c.33-2878_33-2875del,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
607435,3:193329634:C>CT,NM_130837.2:c.33-2868dup,\N,\N,1/30,Unknown significance,\N,intron_variant,2.258,\N,\N,OPA1
607436,3:193329634:C>CTT,NM_130837.2:c.33-2869_33-2868dup,\N,\N,1/30,Unknown significance,\N,intron_variant,2.118,\N,\N,OPA1
607437,3:193329634:C>T,NM_130837.2:c.33-2878C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.017,\N,\N,OPA1
607438,3:193329634:CTT>C,NM_130837.2:c.33-2869_33-2868del,\N,\N,1/30,Unknown significance,\N,intron_variant,3.497,\N,\N,OPA1
607439,3:193329644:T>G,NM_130837.2:c.33-2868T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.896,\N,\N,OPA1
607440,3:193329654:A>G,NM_130837.2:c.33-2858A>G,\N,\N,1/30,Benign,\N,intron_variant,2.336,0.008,1KG_EUR_AF,OPA1
607441,3:193329670:A>AT,NM_130837.2:c.33-2836dup,\N,\N,1/30,Unknown significance,\N,intron_variant,2.16,\N,\N,OPA1
607442,3:193329708:G>T,NM_130837.2:c.33-2804G>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.095,0.001,1KG_EUR_AF,OPA1
607443,3:193329717:C>T,NM_130837.2:c.33-2795C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.546,0.0008,1KG_AFR_AF,OPA1
607444,3:193329718:G>A,NM_130837.2:c.33-2794G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.216,0.0008,1KG_AFR_AF,OPA1
607445,3:193329719:AT>A,NM_130837.2:c.33-2788del,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
607446,3:193329737:G>C,NM_130837.2:c.33-2775G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.104,0.0008,1KG_AFR_AF,OPA1
607447,3:193329754:G>T,NM_130837.2:c.33-2758G>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.911,\N,\N,OPA1
607448,3:193329761:G>A,NM_130837.2:c.33-2751G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.811,\N,\N,OPA1
607449,3:193329763:G>C,NM_130837.2:c.33-2749G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.24,0.001,1KG_EUR_AF,OPA1
607450,3:193329766:C>G,NM_130837.2:c.33-2746C>G,\N,\N,1/30,Benign,\N,intron_variant,1.7,0.5847,1KG_AFR_AF,OPA1
607451,3:193329780:C>A,NM_130837.2:c.33-2732C>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.79,\N,\N,OPA1
607452,3:193329819:C>T,NM_130837.2:c.33-2693C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.084,\N,\N,OPA1
607453,3:193329846:A>G,NM_130837.2:c.33-2666A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.249,\N,\N,OPA1
607454,3:193329880:C>G,NM_130837.2:c.33-2632C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.686,\N,\N,OPA1
607455,3:193329926:C>A,NM_130837.2:c.33-2586C>A,\N,\N,1/30,Unknown significance,\N,intron_variant,5.436,0.001,1KG_EAS_AF,OPA1
607456,3:193329941:A>T,NM_130837.2:c.33-2571A>T,\N,\N,1/30,Unknown significance,\N,intron_variant,11.35,0.001,1KG_SAS_AF,OPA1
607457,3:193329955:C>T,NM_130837.2:c.33-2557C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,11.15,0.003,1KG_EAS_AF,OPA1
607458,3:193329964:T>A,NM_130837.2:c.33-2548T>A,\N,\N,1/30,Unknown significance,\N,intron_variant,10.26,\N,\N,OPA1
607459,3:193329994:T>C,NM_130837.2:c.33-2518T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,7.526,\N,\N,OPA1
607460,3:193330022:T>G,NM_130837.2:c.33-2490T>G,\N,\N,1/30,Benign,\N,intron_variant,2.896,0.5847,1KG_AFR_AF,OPA1
607461,3:193330054:TTCC>T,NM_130837.2:c.33-2456_33-2454del,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
607462,3:193330057:C>CT,NM_130837.2:c.33-2433dup,\N,\N,1/30,Unknown significance,\N,intron_variant,5.074,\N,\N,OPA1
607463,3:193330057:CT>C,NM_130837.2:c.33-2433del,\N,\N,1/30,Unknown significance,\N,intron_variant,4.539,\N,\N,OPA1
607464,3:193330079:T>A,NM_130837.2:c.33-2433T>A,\N,\N,1/30,Unknown significance,\N,intron_variant,4.774,\N,\N,OPA1
607465,3:193330094:G>A,NM_130837.2:c.33-2418G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,2.167,\N,\N,OPA1
607466,3:193330113:A>G,NM_130837.2:c.33-2399A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,3.166,\N,\N,OPA1
607467,3:193330118:T>G,NM_130837.2:c.33-2394T>G,\N,\N,1/30,Benign,\N,intron_variant,0.348,0.4597,1KG_AMR_AF,OPA1
607468,3:193330152:C>A,NM_130837.2:c.33-2360C>A,\N,\N,1/30,Unknown significance,\N,intron_variant,4.921,\N,\N,OPA1
607469,3:193330153:A>T,NM_130837.2:c.33-2359A>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.251,0.001,1KG_SAS_AF,OPA1
607470,3:193330182:C>G,NM_130837.2:c.33-2330C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.585,0.001,1KG_SAS_AF,OPA1
607471,3:193330302:G>A,NM_130837.2:c.33-2210G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.703,\N,\N,OPA1
607472,3:193330316:A>T,NM_130837.2:c.33-2196A>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.954,0.0008,1KG_AFR_AF,OPA1
607473,3:193330359:A>T,NM_130837.2:c.33-2153A>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.332,0.001,1KG_SAS_AF,OPA1
607474,3:193330376:A>G,NM_130837.2:c.33-2136A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,13.96,\N,\N,OPA1
607475,3:193330405:T>G,NM_130837.2:c.33-2107T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.476,\N,\N,OPA1
607476,3:193330421:A>G,NM_130837.2:c.33-2091A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.563,\N,\N,OPA1
607477,3:193330437:G>T,NM_130837.2:c.33-2075G>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.054,\N,\N,OPA1
607478,3:193330458:A>G,NM_130837.2:c.33-2054A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.038,\N,\N,OPA1
607479,3:193330475:C>G,NM_130837.2:c.33-2037C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,3.54,\N,\N,OPA1
607480,3:193330489:C>T,NM_130837.2:c.33-2023C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.638,0.0015,1KG_AFR_AF,OPA1
607481,3:193330490:G>A,NM_130837.2:c.33-2022G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.672,0.0014,1KG_AMR_AF,OPA1
607482,3:193330499:G>C,NM_130837.2:c.33-2013G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.859,\N,\N,OPA1
607483,3:193330548:C>T,NM_130837.2:c.33-1964C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.388,0.0008,1KG_AFR_AF,OPA1
607484,3:193330556:A>G,NM_130837.2:c.33-1956A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.021,0.0014,1KG_AMR_AF,OPA1
607485,3:193330588:T>C,NM_130837.2:c.33-1924T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.79,\N,\N,OPA1
607486,3:193330600:A>G,NM_130837.2:c.33-1912A>G,\N,\N,1/30,Benign,\N,intron_variant,2.67,0.0053,1KG_AFR_AF,OPA1
607487,3:193330633:G>A,NM_130837.2:c.33-1879G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,5.824,0.003,1KG_EUR_AF,OPA1
607488,3:193330668:C>T,NM_130837.2:c.33-1844C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.76,0.0014,1KG_AMR_AF,OPA1
607489,3:193330683:A>T,NM_130837.2:c.33-1829A>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.367,0.001,1KG_EAS_AF,OPA1
607490,3:193330686:A>G,NM_130837.2:c.33-1826A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,4.805,0.002,1KG_SAS_AF,OPA1
607491,3:193330691:G>A,NM_130837.2:c.33-1821G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.019,\N,\N,OPA1
607492,3:193330699:C>T,NM_130837.2:c.33-1813C>T,\N,\N,1/30,Benign,\N,intron_variant,0.594,0.0234,1KG_AFR_AF,OPA1
607493,3:193330700:G>A,NM_130837.2:c.33-1812G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.344,\N,\N,OPA1
607494,3:193330741:CAA>C,NM_130837.2:c.33-1770_33-1769del,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
607495,3:193330804:G>C,NM_130837.2:c.33-1708G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.35,\N,\N,OPA1
607496,3:193330827:T>A,NM_130837.2:c.33-1685T>A,\N,\N,1/30,Unknown significance,\N,intron_variant,6.821,\N,\N,OPA1
607497,3:193330831:A>G,NM_130837.2:c.33-1681A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,5.013,0.0008,1KG_AFR_AF,OPA1
607498,3:193330849:G>A,NM_130837.2:c.33-1663G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,6.562,0.0038,1KG_AFR_AF,OPA1
607499,3:193330854:A>C,NM_130837.2:c.33-1658A>C,\N,\N,1/30,Unknown significance,\N,intron_variant,4.116,\N,\N,OPA1
607500,3:193330886:G>T,NM_130837.2:c.33-1626G>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.466,\N,\N,OPA1
607501,3:193330887:TTTAA>T,NM_130837.2:c.33-1620_33-1617del,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
607502,3:193330919:A>G,NM_130837.2:c.33-1593A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,4.758,\N,\N,OPA1
607503,3:193330933:C>A,NM_130837.2:c.33-1579C>A,\N,\N,1/30,Unknown significance,\N,intron_variant,5.521,\N,\N,OPA1
607504,3:193330967:A>G,NM_130837.2:c.33-1545A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.309,0.001,1KG_EUR_AF,OPA1
607505,3:193330994:A>T,NM_130837.2:c.33-1518A>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.163,0.001,1KG_EUR_AF,OPA1
607506,3:193330998:G>A,NM_130837.2:c.33-1514G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.181,0.0008,1KG_AFR_AF,OPA1
607507,3:193331031:A>G,NM_130837.2:c.33-1481A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.661,\N,\N,OPA1
607508,3:193331055:C>A,NM_130837.2:c.33-1457C>A,\N,\N,1/30,Unknown significance,\N,intron_variant,2.804,\N,\N,OPA1
607509,3:193331079:C>A,NM_130837.2:c.33-1433C>A,\N,\N,1/30,Unknown significance,\N,intron_variant,2.14,0.001,1KG_SAS_AF,OPA1
607510,3:193331093:A>G,NM_130837.2:c.33-1419A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.267,\N,\N,OPA1
607511,3:193331098:G>C,NM_130837.2:c.33-1414G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.458,\N,\N,OPA1
607512,3:193331129:G>C,NM_130837.2:c.33-1383G>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.604,0.001,1KG_EAS_AF,OPA1
607513,3:193331147:TA>T,NM_130837.2:c.33-1355del,\N,\N,1/30,Benign,\N,intron_variant,1.357,0.4524,1KG_AMR_AF,OPA1
607514,3:193331157:A>T,NM_130837.2:c.33-1355A>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.363,\N,\N,OPA1
607515,3:193331158:T>A,NM_130837.2:c.33-1354T>A,\N,\N,1/30,Unknown significance,\N,intron_variant,2.456,\N,\N,OPA1
607516,3:193331175:C>T,NM_130837.2:c.33-1337C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.155,0.001,1KG_EAS_AF,OPA1
607517,3:193331187:C>G,NM_130837.2:c.33-1325C>G,\N,\N,1/30,Benign,\N,intron_variant,0.713,0.68,1KG_AFR_AF,OPA1
607518,3:193331232:A>G,NM_130837.2:c.33-1280A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.842,\N,\N,OPA1
607519,3:193331278:G>A,NM_130837.2:c.33-1234G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.115,\N,\N,OPA1
607520,3:193331344:CTTCT>C,NM_130837.2:c.33-1165_33-1162del,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
607521,3:193331346:T>C,NM_130837.2:c.33-1166T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.086,\N,\N,OPA1
607522,3:193331356:T>C,NM_130837.2:c.33-1156T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.535,0.001,1KG_EAS_AF,OPA1
607523,3:193331358:T>G,NM_130837.2:c.33-1154T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.809,0.001,1KG_EAS_AF|1KG_SAS_AF,OPA1
607524,3:193331358:TTTTG>T,NM_130837.2:c.33-1138_33-1135del,\N,\N,1/30,Benign,\N,intron_variant,1.177,0.0215,1KG_SAS_AF,OPA1
607525,3:193331374:G>T,NM_130837.2:c.33-1138G>T,\N,\N,1/30,Benign,\N,intron_variant,0.354,0.0408,1KG_EUR_AF,OPA1
607526,3:193331375:T>G,NM_130837.2:c.33-1137T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.804,0.0008,1KG_AFR_AF,OPA1
607527,3:193331378:T>G,NM_130837.2:c.33-1134T>G,\N,\N,1/30,Benign,\N,intron_variant,0.836,0.0265,1KG_AFR_AF,OPA1
607528,3:193331393:G>A,NM_130837.2:c.33-1119G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.362,0.0041,1KG_SAS_AF,OPA1
607529,3:193331420:G>A,NM_130837.2:c.33-1092G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,2.018,0.0008,1KG_AFR_AF,OPA1
607530,3:193331436:A>G,NM_130837.2:c.33-1076A>G,\N,\N,1/30,Benign,\N,intron_variant,2.638,0.0628,1KG_AFR_AF,OPA1
607531,3:193331439:T>G,NM_130837.2:c.33-1073T>G,\N,\N,1/30,Benign,\N,intron_variant,4.129,0.0367,1KG_EAS_AF,OPA1
607532,3:193331461:G>A,NM_130837.2:c.33-1051G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.4,0.0014,1KG_AMR_AF,OPA1
607533,3:193331495:T>C,NM_130837.2:c.33-1017T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.204,0.001,1KG_SAS_AF,OPA1
607534,3:193331510:G>A,NM_130837.2:c.33-1002G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.848,\N,\N,OPA1
607535,3:193331539:G>A,NM_130837.2:c.33-973G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,2.415,\N,\N,OPA1
607536,3:193331556:G>A,NM_130837.2:c.33-956G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.284,0.0008,1KG_AFR_AF,OPA1
607537,3:193331570:T>C,NM_130837.2:c.33-942T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.902,\N,\N,OPA1
607538,3:193331597:C>T,NM_130837.2:c.33-915C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,4.395,0.001,1KG_SAS_AF,OPA1
607539,3:193331625:C>T,NM_130837.2:c.33-887C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,3.172,\N,\N,OPA1
607540,3:193331630:G>A,NM_130837.2:c.33-882G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,2.481,0.001,1KG_EUR_AF,OPA1
607541,3:193331632:G>A,NM_130837.2:c.33-880G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.505,\N,\N,OPA1
607542,3:193331644:G>A,NM_130837.2:c.33-868G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.021,0.0014,1KG_AMR_AF,OPA1
607543,3:193331645:G>A,NM_130837.2:c.33-867G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.289,\N,\N,OPA1
607544,3:193331649:G>A,NM_130837.2:c.33-863G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,0.253,\N,\N,OPA1
607545,3:193331652:C>G,NM_130837.2:c.33-860C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.732,0.0015,1KG_AFR_AF,OPA1
607546,3:193331668:C>G,NM_130837.2:c.33-844C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.536,0.0008,1KG_AFR_AF,OPA1
607547,3:193331674:TA>T,NM_130837.2:c.33-836del,\N,\N,1/30,Unknown significance,\N,intron_variant,4.129,0.000123335,EXAC_AFR_AF,OPA1
607548,3:193331676:A>G,NM_130837.2:c.33-836A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.475,0.0000163564,EXAC_NFE_AF,OPA1
607549,3:193331684:C>T,NM_130837.2:c.33-828C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.889,0.0000163559,EXAC_NFE_AF,OPA1
607550,3:193331687:G>A,NM_130837.2:c.33-825G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,3.307,0.0031,1KG_SAS_AF,OPA1
607551,3:193331691:C>T,NM_130837.2:c.33-821C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.163,0.0000621504,EXAC_SAS_AF,OPA1
607552,3:193331697:A>G,NM_130837.2:c.33-815A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.484,0.0008,1KG_AFR_AF,OPA1
607553,3:193331699:T>G,NM_130837.2:c.33-813T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,4.83,0.0000882145,EXAC_AMR_AF,OPA1
607554,3:193331712:AT>A,NM_130837.2:c.33-794del,\N,\N,1/30,Unknown significance,\N,intron_variant,4.17,0.004,1KG_EAS_AF,OPA1
607555,3:193331726:TAGAATC>T,NM_130837.2:c.33-782_33-777del,\N,\N,1/30,Unknown significance,\N,intron_variant,6.847,\N,\N,OPA1
607556,3:193331733:A>G,NM_130837.2:c.33-779A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,3.077,\N,\N,OPA1
607557,3:193331738:G>A,NM_130837.2:c.33-774G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.216,0.00119048,EXAC_OTH_AF,OPA1
607558,3:193331747:T>G,NM_130837.2:c.33-765T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.684,0.0000880747,EXAC_AMR_AF,OPA1
607559,3:193331750:T>C,NM_130837.2:c.33-762T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.278,0.0000880747,EXAC_AMR_AF,OPA1
607560,3:193331755:A>G,NM_130837.2:c.33-757A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.775,0.0000616751,EXAC_SAS_AF,OPA1
607561,3:193331756:G>T,NM_130837.2:c.33-756G>T,\N,\N,1/30,Unknown significance,\N,intron_variant,1.065,0.0000162935,EXAC_NFE_AF,OPA1
607562,3:193331764:T>C,NM_130837.2:c.33-748T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.289,0.00012273,EXAC_AFR_AF,OPA1
607563,3:193331778:C>T,NM_130837.2:c.33-734C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,3.219,\N,\N,OPA1
607564,3:193331780:A>G,NM_130837.2:c.33-732A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.703,0.0000325892,EXAC_NFE_AF,OPA1
607565,3:193331781:T>C,NM_130837.2:c.33-731T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.156,0.0000162946,EXAC_NFE_AF,OPA1
607566,3:193331784:A>G,NM_130837.2:c.33-728A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.102,0.0000325913,EXAC_NFE_AF,OPA1
607567,3:193331787:C>T,NM_130837.2:c.33-725C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,2.728,0.000121921,EXAC_EAS_AF,OPA1
607568,3:193331792:A>C,NM_130837.2:c.33-720A>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.708,0.0000617208,EXAC_SAS_AF,OPA1
607569,3:193331797:T>C,NM_130837.2:c.33-715T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.263,0.00012276,EXAC_AFR_AF,OPA1
607570,3:193331810:A>G,NM_130837.2:c.33-702A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.092,0.0008,1KG_AFR_AF,OPA1
607571,3:193331845:A>T,NM_130837.2:c.33-667A>T,\N,\N,1/30,Unknown significance,\N,intron_variant,0.24,\N,\N,OPA1
607572,3:193331899:C>G,NM_130837.2:c.33-613C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.173,\N,\N,OPA1
607573,3:193331899:C>T,NM_130837.2:c.33-613C>T,\N,\N,1/30,Benign,\N,intron_variant,0.412,0.0257,1KG_AFR_AF,OPA1
607574,3:193331900:G>A,NM_130837.2:c.33-612G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,2.904,0.0014,1KG_AMR_AF,OPA1
607575,3:193331913:A>G,NM_130837.2:c.33-599A>G,\N,\N,1/30,Benign,\N,intron_variant,1.161,0.0099,1KG_EUR_AF,OPA1
607576,3:193331954:G>A,NM_130837.2:c.33-558G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.292,\N,\N,OPA1
607577,3:193331980:G>GT,NM_130837.2:c.33-531dup,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
607578,3:193332002:T>C,NM_130837.2:c.33-510T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.375,\N,\N,OPA1
607579,3:193332022:T>C,NM_130837.2:c.33-490T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,3.27,\N,\N,OPA1
607580,3:193332023:G>A,NM_130837.2:c.33-489G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,4.294,\N,\N,OPA1
607581,3:193332073:A>C,NM_130837.2:c.33-439A>C,\N,\N,1/30,Unknown significance,\N,intron_variant,16.75,\N,\N,OPA1
607582,3:193332074:A>C,NM_130837.2:c.33-438A>C,\N,\N,1/30,Unknown significance,\N,intron_variant,16,\N,\N,OPA1
607583,3:193332079:T>C,NM_130837.2:c.33-433T>C,\N,\N,1/30,Benign,\N,intron_variant,16.78,0.0257,1KG_AFR_AF,OPA1
607584,3:193332086:A>G,NM_130837.2:c.33-426A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,16.48,0.001,1KG_EAS_AF,OPA1
607585,3:193332102:T>C,NM_130837.2:c.33-410T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,9.468,\N,\N,OPA1
607586,3:193332130:T>A,NM_130837.2:c.33-382T>A,\N,\N,1/30,Unknown significance,\N,intron_variant,1.169,\N,\N,OPA1
607587,3:193332165:A>G,NM_130837.2:c.33-347A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,3.329,\N,\N,OPA1
607588,3:193332187:C>A,NM_130837.2:c.33-325C>A,\N,\N,1/30,Unknown significance,\N,intron_variant,6.926,0.0008,1KG_AFR_AF,OPA1
607589,3:193332188:T>C,NM_130837.2:c.33-324T>C,\N,\N,1/30,Benign,\N,intron_variant,3.667,0.1511,1KG_EUR_AF,OPA1
607590,3:193332227:A>G,NM_130837.2:c.33-285A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,3.917,\N,\N,OPA1
607591,3:193332228:C>CT,NM_130837.2:c.33-281dup,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
607592,3:193332260:A>G,NM_130837.2:c.33-252A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,7.427,0.001,1KG_EAS_AF,OPA1
607593,3:193332312:G>GT,NM_130837.2:c.33-198dup,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
607594,3:193332315:A>AC,NM_130837.2:c.33-197_33-196insC,\N,\N,1/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
607595,3:193332329:A>C,NM_130837.2:c.33-183A>C,\N,\N,1/30,Unknown significance,\N,intron_variant,9.042,\N,\N,OPA1
607596,3:193332342:T>C,NM_130837.2:c.33-170T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.753,0.001,1KG_EAS_AF,OPA1
607597,3:193332361:T>C,NM_130837.2:c.33-151T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,1.491,0.001,1KG_EUR_AF,OPA1
607598,3:193332367:A>G,NM_130837.2:c.33-145A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,2.235,0.001,1KG_EUR_AF|1KG_SAS_AF,OPA1
607599,3:193332371:T>C,NM_130837.2:c.33-141T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,0.87,\N,\N,OPA1
607600,3:193332375:T>C,NM_130837.2:c.33-137T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,2.402,\N,\N,OPA1
607601,3:193332379:T>C,NM_130837.2:c.33-133T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,2.846,0.0029,1KG_AMR_AF,OPA1
607602,3:193332395:A>G,NM_130837.2:c.33-117A>G,\N,\N,1/30,Benign,\N,intron_variant,2.128,0.0061,1KG_AFR_AF,OPA1
607603,3:193332405:T>G,NM_130837.2:c.33-107T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,5.331,0.001,1KG_SAS_AF,OPA1
607604,3:193332412:G>A,NM_130837.2:c.33-100G>A,\N,\N,1/30,Benign,\N,intron_variant,0.711,0.0179,1KG_EAS_AF,OPA1
607605,3:193332420:C>CTGTG,NM_130837.2:c.33-90_33-87dup,\N,\N,1/30,Benign,\N,intron_variant,3.632,0.4284,1KG_EUR_AF,OPA1
607606,3:193332420:C>G,NM_130837.2:c.33-92C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,1.143,\N,\N,OPA1
607607,3:193332435:T>A,NM_130837.2:c.33-77T>A,\N,\N,1/30,Unknown significance,\N,intron_variant,5.456,\N,\N,OPA1
607608,3:193332463:T>G,NM_130837.2:c.33-49T>G,\N,\N,1/30,Unknown significance,\N,intron_variant,10.52,0.0000299922,EXAC_NFE_AF,OPA1
607609,3:193332465:T>C,NM_130837.2:c.33-47T>C,\N,\N,1/30,Unknown significance,\N,intron_variant,9.393,\N,\N,OPA1
607610,3:193332469:G>A,NM_130837.2:c.33-43G>A,\N,\N,1/30,Unknown significance,\N,intron_variant,9.136,0.000231214,EXAC_EAS_AF,OPA1
607611,3:193332475:CT>C,NM_130837.2:c.33-36del,\N,\N,1/30,Unknown significance,\N,intron_variant,11.31,0.0000605987,EXAC_SAS_AF,OPA1
607612,3:193332477:C>G,NM_130837.2:c.33-35C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,8.58,0.000172801,EXAC_AMR_AF,OPA1
607613,3:193332491:C>G,NM_130837.2:c.33-21C>G,\N,\N,1/30,Unknown significance,\N,intron_variant,5.996,0.0000149934,EXAC_NFE_AF,OPA1
607614,3:193332492:C>T,NM_130837.2:c.33-20C>T,\N,\N,1/30,Unknown significance,\N,intron_variant,5.994,0.0000149939,EXAC_NFE_AF,OPA1
607615,3:193332495:A>G,NM_130837.2:c.33-17A>G,\N,\N,1/30,Unknown significance,\N,intron_variant,0.799,0.0000605694,EXAC_SAS_AF,OPA1
607616,3:193332504:T>C,NM_130837.2:c.33-8T>C,\N,\N,1/30,Unknown significance,\N,splice_region_variant&intron_variant,9.174,0.000232558,EVS_EA_AF,OPA1
607617,3:193332512:T>A,NM_130837.2:c.33T>A,NP_570850.2:p.Cys11Ter,2/31,\N,Pathogenic,Optic atrophy,stop_gained&splice_region_variant,35,\N,\N,OPA1
607618,3:193332516:G>A,NM_130837.2:c.37G>A,NP_570850.2:p.Val13Ile,2/31,\N,Unknown significance,\N,missense_variant,20.5,0.000116279,EVS_EA_AF,OPA1
607619,3:193332520:G>A,NM_130837.2:c.41G>A,NP_570850.2:p.Cys14Tyr,2/31,\N,Unknown significance,\N,missense_variant,28.1,0.000014988,EXAC_NFE_AF,OPA1
607620,3:193332522:C>A,NM_130837.2:c.43C>A,NP_570850.2:p.Gln15Lys,2/31,\N,Benign,\N,missense_variant,19.05,0.0222895,EXAC_SAS_AF,OPA1
607621,3:193332528:T>A,NM_130837.2:c.49T>A,NP_570850.2:p.Leu17Ile,2/31,\N,Unknown significance,\N,missense_variant,23.2,0.0000149862,EXAC_NFE_AF,OPA1
607622,3:193332528:T>TGG,NM_130837.2:c.49_50insGG,NP_570850.2:p.Leu17TrpfsTer2,2/31,\N,Pathogenic,Optic atrophy,frameshift_variant,35,\N,\N,OPA1
607623,3:193332549:A>G,NM_130837.2:c.70A>G,NP_570850.2:p.Ile24Val,2/31,\N,Likely benign,\N,missense_variant,0.002,0.000464559,EXAC_NFE_AF,OPA1
607624,3:193332550:T>A,NM_130837.2:c.71T>A,NP_570850.2:p.Ile24Lys,2/31,\N,Unknown significance,\N,missense_variant,21.4,0.0000605694,EXAC_SAS_AF,OPA1
607625,3:193332550:T>C,NM_130837.2:c.71T>C,NP_570850.2:p.Ile24Thr,2/31,\N,Unknown significance,\N,missense_variant,10.29,0.001,1KG_SAS_AF,OPA1
607626,3:193332550:TAA>AG,NM_130837.2:c.71_73delinsAG,NP_570850.2:p.Ile24LysfsTer25,2/31,\N,Pathogenic,Optic atrophy,frameshift_variant,\N,\N,\N,OPA1
607627,3:193332559:G>A,NM_130837.2:c.80G>A,NP_570850.2:p.Ser27Asn,2/31,\N,Likely benign,\N,missense_variant,5.656,\N,\N,OPA1
607628,3:193332564:C>G,NM_130837.2:c.85C>G,NP_570850.2:p.Pro29Ala,2/31,\N,Benign,\N,missense_variant,15.8,0.0053,1KG_AFR_AF,OPA1
607629,3:193332566:A>G,NM_130837.2:c.87A>G,NP_570850.2:p.Pro29=,2/31,\N,Unknown significance,\N,synonymous_variant,6.498,0.0000149862,EXAC_NFE_AF,OPA1
607630,3:193332567:C>T,NM_130837.2:c.88C>T,NP_570850.2:p.Leu30=,2/31,\N,Benign,\N,synonymous_variant,14.12,0.0029,1KG_AMR_AF,OPA1
607631,3:193332568:T>C,NM_130837.2:c.89T>C,NP_570850.2:p.Leu30Pro,2/31,\N,Unknown significance,\N,missense_variant,21.2,0.0000605694,EXAC_SAS_AF,OPA1
607632,3:193332570:C>CAAAA,NM_130837.2:c.93_96dup,NP_570850.2:p.Leu33LysfsTer41,2/31,\N,Pathogenic,Optic neuropathy,frameshift_variant,34,\N,\N,OPA1
607633,3:193332575:A>G,NM_130837.2:c.96A>G,NP_570850.2:p.Lys32=,2/31,\N,Unknown significance,\N,synonymous_variant,6.652,0.0000149867,EXAC_NFE_AF,OPA1
607634,3:193332579:C>T,NM_130837.2:c.100C>T,NP_570850.2:p.His34Tyr,2/31,\N,Unknown significance,\N,missense_variant,22.5,0.0000149894,EXAC_NFE_AF,OPA1
607635,3:193332583:T>C,NM_130837.2:c.104T>C,NP_570850.2:p.Leu35Pro,2/31,\N,Unknown significance,\N,missense_variant,20.5,\N,\N,OPA1
607636,3:193332586:TTTCACGAAGCATTTATCA>T,NM_130837.2:c.113_130del,NP_570850.2:p.Arg38_Ser43del,2/31,\N,Benign,\N,inframe_deletion,22,\N,\N,OPA1
607637,3:193332589:C>T,NM_015560.2:c.110C>T,NP_056375.2:p.Ser37Leu,2/29,\N,Unknown significance,\N,missense_variant,25,0.000116279,EVS_EA_AF,OPA1
607638,3:193332591:C>G,NM_130837.2:c.112C>G,NP_570850.2:p.Arg38Gly,2/31,\N,Unknown significance,\N,missense_variant,25.3,\N,\N,OPA1
607639,3:193332591:C>T,NM_130837.2:c.112C>T,NP_570850.2:p.Arg38Ter,2/31,\N,Pathogenic,Optic atrophy 1,stop_gained,38,\N,\N,OPA1
607640,3:193332599:T>G,NM_130837.2:c.120T>G,NP_570850.2:p.Ile40Met,2/31,\N,Unknown significance,\N,missense_variant,21.3,0.000242277,EXAC_SAS_AF,OPA1
607641,3:193332603:C>A,NM_130837.2:c.124C>A,NP_570850.2:p.His42Asn,2/31,\N,Unknown significance,\N,missense_variant,20.4,0.0000605694,EXAC_SAS_AF,OPA1
607642,3:193332603:C>T,NM_130837.2:c.124C>T,NP_570850.2:p.His42Tyr,2/31,\N,Unknown significance,\N,missense_variant,18.08,0.000232558,EVS_EA_AF,OPA1
607643,3:193332626:G>A,NM_130837.2:c.147G>A,NP_570850.2:p.Lys49=,2/31,\N,Unknown significance,\N,synonymous_variant,10.45,0.000115982,EXAC_EAS_AF,OPA1
607644,3:193332631:A>G,NM_130837.2:c.152A>G,NP_570850.2:p.Gln51Arg,2/31,\N,Unknown significance,\N,missense_variant,13.45,0.000226963,EVS_AA_AF,OPA1
607645,3:193332633:C>T,NM_130837.2:c.154C>T,NP_570850.2:p.Arg52Ter,2/31,\N,Pathogenic,Optic atrophy 1,stop_gained,35,\N,\N,OPA1
607646,3:193332634:G>A,NM_130837.2:c.155G>A,NP_570850.2:p.Arg52Gln,2/31,\N,Unknown significance,\N,missense_variant,25.2,0.000015011,EXAC_NFE_AF,OPA1
607647,3:193332638:C>G,NM_130837.2:c.159C>G,NP_570850.2:p.Pro53=,2/31,\N,Unknown significance,\N,synonymous_variant,8.106,\N,\N,OPA1
607648,3:193332640:A>G,NM_130837.2:c.161A>G,NP_570850.2:p.Gln54Arg,2/31,\N,Unknown significance,\N,missense_variant,8.046,0.0000450911,EXAC_NFE_AF,OPA1
607649,3:193332641:A>G,NM_130837.2:c.162A>G,NP_570850.2:p.Gln54=,2/31,\N,Unknown significance,\N,synonymous_variant,5.002,0.000116795,EXAC_EAS_AF,OPA1
607650,3:193332649:C>T,NM_130837.2:c.170C>T,NP_570850.2:p.Thr57Ile,2/31,\N,Likely benign,\N,missense_variant,18.75,\N,\N,OPA1
607651,3:193332660:C>T,NM_130837.2:c.181C>T,NP_570850.2:p.Gln61Ter,2/31,\N,Pathogenic,Optic atrophy 1,stop_gained,36,\N,\N,OPA1
607652,3:193332661:A>G,NM_130837.2:c.182A>G,NP_570850.2:p.Gln61Arg,2/31,\N,Benign,\N,missense_variant,11.94,0.0072,1KG_SAS_AF,OPA1
607653,3:193332662:GTTCTC>G,NM_130837.2:c.190_194del,NP_570850.2:p.Ser64AspfsTer7,2/31,\N,Pathogenic,Optic atrophy,frameshift_variant,34,\N,\N,OPA1
607654,3:193332666:T>A,NM_130837.2:c.187T>A,NP_570850.2:p.Ser63Thr,2/31,\N,Unknown significance,\N,missense_variant,13.86,0.00111111,EXAC_OTH_AF,OPA1
607655,3:193332667:CT>C,NM_130837.2:c.190del,NP_570850.2:p.Ser64LeufsTer2,2/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,24.8,\N,\N,OPA1
607656,3:193332674:G>C,NM_130837.2:c.195G>C,NP_570850.2:p.Leu65=,2/31,\N,Unknown significance,\N,synonymous_variant,8.279,0.0000151263,EXAC_NFE_AF,OPA1
607657,3:193332680:C>T,NM_130837.2:c.201C>T,NP_570850.2:p.Asn67=,2/31,\N,Unknown significance,\N,synonymous_variant,11.03,0.000116279,EVS_EA_AF,OPA1
607658,3:193332684:C>G,NM_130837.2:c.205C>G,NP_570850.2:p.Pro69Ala,2/31,\N,Likely benign,\N,missense_variant,13.91,0.0000303131,EXAC_NFE_AF,OPA1
607659,3:193332690:C>T,NM_015560.2:c.211C>T,NP_056375.2:p.Arg71Cys,2/29,\N,Likely pathogenic,\N,missense_variant,26.3,0.000453926,EVS_AA_AF,OPA1
607660,3:193332691:G>A,NM_130837.2:c.212G>A,NP_570850.2:p.Arg71His,2/31,\N,Unknown significance,\N,missense_variant,24.5,0.000060733,EXAC_NFE_AF,OPA1
607661,3:193332694:A>C,NM_130837.2:c.215A>C,NP_570850.2:p.Lys72Thr,2/31,\N,Unknown significance,\N,missense_variant,14.4,0.001,1KG_EAS_AF,OPA1
607662,3:193332695:A>G,NM_130837.2:c.216A>G,NP_570850.2:p.Lys72=,2/31,\N,Unknown significance,\N,synonymous_variant,6.514,0.00012025,EXAC_EAS_AF,OPA1
607663,3:193332701:A>T,NM_130837.2:c.222A>T,NP_570850.2:p.Lys74Asn,2/31,\N,Unknown significance,\N,missense_variant,14.49,0.00106486,EXAC_AFR_AF,OPA1
607664,3:193332716:A>T,NM_130837.2:c.237A>T,NP_570850.2:p.Lys79Asn,2/31,\N,Likely benign,\N,missense_variant,11.88,0.000608643,EXAC_FIN_AF,OPA1
607665,3:193332718:A>G,NM_130837.2:c.239A>G,NP_570850.2:p.Tyr80Cys,2/31,\N,Pathogenic,Optic atrophy 1,missense_variant,16.18,0.0038,1KG_AFR_AF,OPA1
607666,3:193332719:T>C,NM_130837.2:c.240T>C,NP_570850.2:p.Tyr80=,2/31,\N,Unknown significance,\N,synonymous_variant,1.143,0.0000151828,EXAC_NFE_AF,OPA1
607667,3:193332724:A>G,NM_130837.2:c.245A>G,NP_570850.2:p.Tyr82Cys,2/31,\N,Unknown significance,\N,missense_variant,24.2,0.0000757599,EXAC_NFE_AF,OPA1
607668,3:193332725:C>A,NM_130837.2:c.246C>A,NP_570850.2:p.Tyr82Ter,2/31,\N,Unknown significance,\N,stop_gained,36,\N,\N,OPA1
607669,3:193332728:G>A,NM_130837.2:c.249G>A,NP_570850.2:p.Gln83=,2/31,\N,Unknown significance,\N,synonymous_variant,6.65,\N,\N,OPA1
607670,3:193332730:C>T,NM_130837.2:c.251C>T,NP_570850.2:p.Pro84Leu,2/31,\N,Likely benign,\N,missense_variant,22.6,0.00004532,EXAC_NFE_AF,OPA1
607671,3:193332731:T>C,NM_130837.2:c.252T>C,NP_570850.2:p.Pro84=,2/31,\N,Unknown significance,\N,synonymous_variant,0.136,0.000303951,EXAC_FIN_AF,OPA1
607672,3:193332732:C>A,NM_130837.2:c.253C>A,NP_570850.2:p.Arg85Ser,2/31,\N,Likely benign,\N,missense_variant,17.54,0.000117398,EXAC_EAS_AF,OPA1
607673,3:193332732:C>G,NM_130837.2:c.253C>G,NP_570850.2:p.Arg85Gly,2/31,\N,Likely benign,\N,missense_variant,16.39,0.000116279,EVS_EA_AF,OPA1
607674,3:193332732:C>T,NM_130837.2:c.253C>T,NP_570850.2:p.Arg85Cys,2/31,\N,Benign,\N,missense_variant,23.5,0.0051,1KG_SAS_AF,OPA1
607675,3:193332733:G>A,NM_130837.2:c.254G>A,NP_570850.2:p.Arg85His,2/31,\N,Benign,\N,missense_variant,12,0.003,1KG_AFR_AF,OPA1
607676,3:193332735:A>G,NM_130837.2:c.256A>G,NP_570850.2:p.Arg86Gly,2/31,\N,Unknown significance,\N,missense_variant,25.2,0.0000606722,EXAC_SAS_AF,OPA1
607677,3:193332741:T>C,NM_130834.2:c.262T>C,NP_570847.2:p.Phe88Leu,2/30,\N,Unknown significance,\N,missense_variant,22.7,0.0008,1KG_AFR_AF,OPA1
607678,3:193332750:G>A,NM_130837.2:c.271G>A,NP_570850.2:p.Ala91Thr,2/31,\N,Unknown significance,\N,missense_variant,23,0.0000869263,EXAC_AMR_AF,OPA1
607679,3:193332750:G>C,NM_130837.2:c.271G>C,NP_570850.2:p.Ala91Pro,2/31,\N,Unknown significance,\N,missense_variant,27.6,0.000115821,EXAC_EAS_AF,OPA1
607680,3:193332757:T>C,NM_130837.2:c.278T>C,NP_570850.2:p.Leu93Ser,2/31,\N,Unknown significance,\N,missense_variant,26.3,0.0000867604,EXAC_AMR_AF,OPA1
607681,3:193332760:C>T,NM_130834.2:c.281C>T,NP_570847.2:p.Ala94Val,2/30,\N,Unknown significance,\N,missense_variant,16.57,0.0000867002,EXAC_AMR_AF,OPA1
607682,3:193332763:C>G,NM_130837.2:c.284C>G,NP_570850.2:p.Thr95Arg,2/31,\N,Unknown significance,\N,missense_variant,15.19,0.000151286,EXAC_FIN_AF,OPA1
607683,3:193332763:C>T,NM_130837.2:c.284C>T,NP_570850.2:p.Thr95Met,2/31,\N,Pathogenic,Optic atrophy 1,missense_variant,24.9,0.00110619,EXAC_OTH_AF,OPA1
607684,3:193332764:G>A,NM_130837.2:c.285G>A,NP_570850.2:p.Thr95=,2/31,\N,Unknown significance,\N,synonymous_variant,12.5,0.0000150011,EXAC_NFE_AF,OPA1
607685,3:193332768:CTCTTAAAACT>C,NM_130837.2:c.292_301del,NP_570850.2:p.Leu98AlafsTer5,2/31,\N,Pathogenic,Dominant hereditary optic atrophy,frameshift_variant,\N,\N,\N,OPA1
607686,3:193332768:C>G,NM_015560.2:c.289C>G,NP_056375.2:p.Leu97Val,2/29,\N,Unknown significance,\N,missense_variant,12.52,0.000226963,EVS_AA_AF,OPA1
607687,3:193332780:C>T,NM_130837.2:c.301C>T,NP_570850.2:p.Arg101Cys,2/31,\N,Unknown significance,\N,missense_variant,31,0.000151194,EXAC_FIN_AF,OPA1
607688,3:193332781:G>A,NM_130837.2:c.302G>A,NP_570850.2:p.Arg101His,2/31,\N,Unknown significance,\N,missense_variant,32,0.0000605987,EXAC_SAS_AF,OPA1
607689,3:193332784:A>G,NM_015560.2:c.305A>G,NP_056375.2:p.Tyr102Cys,2/29,\N,Pathogenic,Optic atrophy 1,missense_variant,25.7,0.0008,1KG_AFR_AF,OPA1
607690,3:193332791:A>G,NM_130837.2:c.312A>G,NP_570850.2:p.Ile104Met,2/31,\N,Pathogenic,Spastic paraparesis & intestinal dysmotility,missense_variant,13.45,0.000060584,EXAC_SAS_AF,OPA1
607691,3:193332795:G>C,NM_130837.2:c.316G>C,NP_570850.2:p.Gly106Arg,2/31,\N,Unknown significance,\N,missense_variant,25,0.0000150056,EXAC_NFE_AF,OPA1
607692,3:193332799:C>T,NM_130837.2:c.320C>T,NP_570850.2:p.Ser107Leu,2/31,\N,Unknown significance,\N,missense_variant,23.7,0.000121183,EXAC_SAS_AF,OPA1
607693,3:193332800:G>A,NM_130837.2:c.321G>A,NP_570850.2:p.Ser107=,2/31,\N,Benign,\N,synonymous_variant,11.14,0.0219947,EXAC_SAS_AF,OPA1
607694,3:193332803:T>TG,NM_130837.2:c.325dup,NP_570850.2:p.Val109GlyfsTer12,2/31,\N,Unknown significance,\N,frameshift_variant,34,\N,\N,OPA1
607695,3:193332805:T>C,NM_130833.2:c.326T>C,NP_570846.1:p.Val109Ala,2/29,\N,Unknown significance,\N,missense_variant,23.1,\N,\N,OPA1
607696,3:193332805:T>G,NM_130836.2:c.326T>G,NP_570849.2:p.Val109Gly,2/30,\N,Unknown significance,\N,missense_variant,23.3,\N,\N,OPA1
607697,3:193332806:T>G,NM_130837.2:c.327T>G,NP_570850.2:p.Val109=,2/31,\N,Unknown significance,\N,synonymous_variant,8.543,\N,\N,OPA1
607698,3:193332808:G>C,NM_130837.2:c.329G>C,NP_570850.2:p.Gly110Ala,2/31,\N,Unknown significance,\N,missense_variant,19.18,0.0000605987,EXAC_SAS_AF,OPA1
607699,3:193332812:T>G,NM_130837.2:c.333T>G,NP_570850.2:p.Gly111=,2/31,\N,Unknown significance,\N,synonymous_variant,8.916,\N,\N,OPA1
607700,3:193332818:C>T,NM_130837.2:c.339C>T,NP_570850.2:p.Tyr113=,2/31,\N,Unknown significance,\N,synonymous_variant,6.061,0.0000451128,EXAC_NFE_AF,OPA1
607701,3:193332821:A>T,NM_130837.2:c.342A>T,NP_570850.2:p.Thr114=,2/31,\N,Unknown significance,\N,synonymous_variant,0.01,0.0000606134,EXAC_SAS_AF,OPA1
607702,3:193332823:C>T,NM_015560.2:c.344C>T,NP_056375.2:p.Ala115Val,2/29,\N,Pathogenic,Optic atrophy| ataxia & neuropathy,missense_variant,19.22,0.001,1KG_EUR_AF,OPA1
607703,3:193332829:A>T,NM_130835.2:c.350A>T,NP_570848.1:p.Lys117Met,2/30,\N,Unknown significance,\N,missense_variant&splice_region_variant,25,0.0000606281,EXAC_SAS_AF,OPA1
607704,3:193332837:T>C,NM_130837.2:c.351+7T>C,\N,\N,2/30,Unknown significance,\N,splice_region_variant&intron_variant,1.507,\N,\N,OPA1
607705,3:193332843:T>G,NM_130837.2:c.351+13T>G,\N,\N,2/30,Unknown significance,\N,intron_variant,7.544,0.0000302636,EXAC_NFE_AF,OPA1
607706,3:193332845:C>A,NM_130837.2:c.351+15C>A,\N,\N,2/30,Unknown significance,\N,intron_variant,6.751,\N,\N,OPA1
607707,3:193332846:C>T,NM_130837.2:c.351+16C>T,\N,\N,2/30,Unknown significance,\N,intron_variant,3.402,0.0000151378,EXAC_NFE_AF,OPA1
607708,3:193332851:G>T,NM_130837.2:c.351+21G>T,\N,\N,2/30,Unknown significance,\N,intron_variant,2.113,0.000103284,EXAC_AFR_AF,OPA1
607709,3:193332864:TTA>T,NM_130837.2:c.351+38_351+39del,\N,\N,2/30,Unknown significance,\N,intron_variant,10.36,0.000116686,EXAC_EAS_AF,OPA1
607710,3:193332864:T>C,NM_130837.2:c.351+34T>C,\N,\N,2/30,Unknown significance,\N,intron_variant,8.093,0.000583431,EXAC_EAS_AF,OPA1
607711,3:193332868:A>G,NM_130837.2:c.351+38A>G,\N,\N,2/30,Unknown significance,\N,intron_variant,6.649,0.0000152476,EXAC_NFE_AF,OPA1
607712,3:193332871:A>T,NM_130837.2:c.351+41A>T,\N,\N,2/30,Unknown significance,\N,intron_variant,7.17,0.0041,1KG_SAS_AF,OPA1
607713,3:193332873:G>A,NM_130837.2:c.351+43G>A,\N,\N,2/30,Unknown significance,\N,intron_variant,8.991,0.000105731,EXAC_AFR_AF,OPA1
607714,3:193332874:A>T,NM_130837.2:c.351+44A>T,\N,\N,2/30,Unknown significance,\N,intron_variant,7.216,0.000117014,EXAC_EAS_AF,OPA1
607715,3:193332890:A>G,NM_130837.2:c.351+60A>G,\N,\N,2/30,Unknown significance,\N,intron_variant,5.45,\N,\N,OPA1
607716,3:193332908:G>A,NM_130837.2:c.351+78G>A,\N,\N,2/30,Benign,\N,intron_variant,5.773,0.1051,1KG_AFR_AF,OPA1
607717,3:193332914:T>A,NM_130837.2:c.351+84T>A,\N,\N,2/30,Unknown significance,\N,intron_variant,8.971,\N,\N,OPA1
607718,3:193332935:T>G,NM_130837.2:c.351+105T>G,\N,\N,2/30,Unknown significance,\N,intron_variant,9.581,0.001,1KG_EAS_AF,OPA1
607719,3:193332990:G>A,NM_130837.2:c.351+160G>A,\N,\N,2/30,Unknown significance,\N,intron_variant,0.933,\N,\N,OPA1
607720,3:193333004:A>G,NM_130837.2:c.351+174A>G,\N,\N,2/30,Unknown significance,\N,intron_variant,3.132,0.0008,1KG_AFR_AF,OPA1
607721,3:193333010:A>G,NM_130837.2:c.351+180A>G,\N,\N,2/30,Benign,\N,intron_variant,3.983,0.1051,1KG_AFR_AF,OPA1
607722,3:193333032:C>G,NM_130837.2:c.351+202C>G,\N,\N,2/30,Unknown significance,\N,intron_variant,5.483,\N,\N,OPA1
607723,3:193333056:G>GA,NM_130837.2:c.351+228dup,\N,\N,2/30,Benign,\N,intron_variant,2.661,0.1051,1KG_AFR_AF,OPA1
607724,3:193333070:A>G,NM_130837.2:c.351+240A>G,\N,\N,2/30,Unknown significance,\N,intron_variant,4.139,0.0014,1KG_AMR_AF,OPA1
607725,3:193333105:G>C,NM_130837.2:c.351+275G>C,\N,\N,2/30,Benign,\N,intron_variant,0.792,0.0507,1KG_AFR_AF,OPA1
607726,3:193333126:T>C,NM_130837.2:c.351+296T>C,\N,\N,2/30,Benign,\N,intron_variant,2.193,0.0256,1KG_SAS_AF,OPA1
607727,3:193333131:C>T,NM_130837.2:c.351+301C>T,\N,\N,2/30,Unknown significance,\N,intron_variant,4.038,\N,\N,OPA1
607728,3:193333137:C>G,NM_130837.2:c.351+307C>G,\N,\N,2/30,Unknown significance,\N,intron_variant,5.379,0.0038,1KG_AFR_AF,OPA1
607729,3:193333146:G>A,NM_130837.2:c.351+316G>A,\N,\N,2/30,Unknown significance,\N,intron_variant,5.19,0.0008,1KG_AFR_AF,OPA1
607730,3:193333166:A>G,NM_130837.2:c.352-297A>G,\N,\N,2/30,Unknown significance,\N,intron_variant,8.111,\N,\N,OPA1
607731,3:193333170:C>T,NM_130837.2:c.352-293C>T,\N,\N,2/30,Unknown significance,\N,intron_variant,1.838,0.0008,1KG_AFR_AF,OPA1
607732,3:193333171:G>A,NM_130837.2:c.352-292G>A,\N,\N,2/30,Unknown significance,\N,intron_variant,0.113,\N,\N,OPA1
607733,3:193333191:T>C,NM_130837.2:c.352-272T>C,\N,\N,2/30,Unknown significance,\N,intron_variant,4.23,0.0008,1KG_AFR_AF,OPA1
607734,3:193333228:T>C,NM_130837.2:c.352-235T>C,\N,\N,2/30,Unknown significance,\N,intron_variant,3.332,\N,\N,OPA1
607735,3:193333234:C>G,NM_130837.2:c.352-229C>G,\N,\N,2/30,Unknown significance,\N,intron_variant,10.81,0.0029,1KG_AMR_AF,OPA1
607736,3:193333275:A>G,NM_130837.2:c.352-188A>G,\N,\N,2/30,Unknown significance,\N,intron_variant,5.454,0.001,1KG_EUR_AF,OPA1
607737,3:193333320:G>A,NM_130837.2:c.352-143G>A,\N,\N,2/30,Unknown significance,\N,intron_variant,11.99,0.003,1KG_EUR_AF,OPA1
607738,3:193333330:A>G,NM_130837.2:c.352-133A>G,\N,\N,2/30,Unknown significance,\N,intron_variant,11.49,0.0014,1KG_AMR_AF,OPA1
607739,3:193333424:A>T,NM_130837.2:c.352-39A>T,\N,\N,2/30,Unknown significance,\N,intron_variant,3.51,0.000487805,EXAC_AFR_AF,OPA1
607740,3:193333425:T>C,NM_130837.2:c.352-38T>C,\N,\N,2/30,Unknown significance,\N,intron_variant,4.518,0.000115554,EXAC_EAS_AF,OPA1
607741,3:193333458:T>C,NM_130837.2:c.352-5T>C,\N,\N,2/30,Unknown significance,\N,splice_region_variant&intron_variant,11.84,0.0000149844,EXAC_NFE_AF,OPA1
607742,3:193333459:T>G,NM_130837.2:c.352-4T>G,\N,\N,2/30,Unknown significance,\N,splice_region_variant&intron_variant,12.71,0.000060562,EXAC_SAS_AF,OPA1
607743,3:193333460:T>C,NM_130837.2:c.352-3T>C,\N,\N,2/30,Unknown significance,\N,splice_region_variant&intron_variant,13.11,0.000115554,EXAC_EAS_AF,OPA1
607744,3:193333464:CTT>C,NM_130837.2:c.356_357del,NP_570850.2:p.Phe119Ter,3/31,\N,Pathogenic,Optic atrophy,frameshift_variant&splice_region_variant,32,\N,\N,OPA1
607745,3:193333472:C>T,NM_130837.2:c.361C>T,NP_570850.2:p.Gln121Ter,3/31,\N,Pathogenic,Optic atrophy 1,stop_gained,37,\N,\N,OPA1
607746,3:193333475:T>C,NM_130837.2:c.364T>C,NP_570850.2:p.Trp122Arg,3/31,\N,Unknown significance,\N,missense_variant,27.8,\N,\N,OPA1
607747,3:193333489:A>G,NM_130837.2:c.378A>G,NP_570850.2:p.Ile126Met,3/31,\N,Likely benign,\N,missense_variant,13.5,\N,\N,OPA1
607748,3:193333490:C>T,NM_130837.2:c.379C>T,NP_570850.2:p.Pro127Ser,3/31,\N,Unknown significance,\N,missense_variant,28.8,\N,\N,OPA1
607749,3:193333491:C>T,NM_130837.2:c.380C>T,NP_570850.2:p.Pro127Leu,3/31,\N,Unknown significance,\N,missense_variant,34,0.000060562,EXAC_SAS_AF,OPA1
607750,3:193333492:G>A,NM_130837.2:c.381G>A,NP_570850.2:p.Pro127=,3/31,\N,Unknown significance,\N,synonymous_variant,13.77,0.000115554,EXAC_EAS_AF,OPA1
607751,3:193333496:C>T,NM_130837.2:c.385C>T,NP_570850.2:p.Leu129Phe,3/31,\N,Unknown significance,\N,missense_variant,22.3,\N,\N,OPA1
607752,3:193333500:G>C,NM_130837.2:c.389G>C,NP_570850.2:p.Ser130Thr,3/31,\N,Unknown significance,\N,missense_variant,18.59,0.0000149853,EXAC_NFE_AF,OPA1
607753,3:193333527:T>C,NM_130837.2:c.416T>C,NP_570850.2:p.Ile139Thr,3/31,\N,Unknown significance,\N,missense_variant,13.12,0.000116306,EVS_EA_AF,OPA1
607754,3:193333531:G>T,NM_130837.2:c.420G>T,NP_570850.2:p.Val140=,3/31,\N,Benign,\N,synonymous_variant,11.34,0.0127786,EXAC_SAS_AF,OPA1
607755,3:193333531:G>A,NM_130837.2:c.420G>A,NP_570850.2:p.Val140=,3/31,\N,Unknown significance,\N,synonymous_variant,11.71,0.0000149853,EXAC_NFE_AF,OPA1
607756,3:193333540:T>C,NM_130837.2:c.429T>C,NP_570850.2:p.Ile143=,3/31,\N,Unknown significance,\N,synonymous_variant,8.546,0.000242248,EXAC_SAS_AF,OPA1
607757,3:193333548:A>G,NM_130837.2:c.437A>G,NP_570850.2:p.Tyr146Cys,3/31,\N,Unknown significance,\N,missense_variant,23.9,0.0000149853,EXAC_NFE_AF,OPA1
607758,3:193333552:C>A,NM_130837.2:c.441C>A,NP_570850.2:p.Ile147=,3/31,\N,Unknown significance,\N,synonymous_variant,22.6,0.000060562,EXAC_SAS_AF,OPA1
607759,3:193333553:G>A,NM_130837.2:c.442G>A,NP_570850.2:p.Asp148Asn,3/31,\N,Unknown significance,\N,missense_variant,27.3,0.000121124,EXAC_SAS_AF,OPA1
607760,3:193333560:G>C,NM_130837.2:c.448+1G>C,\N,\N,3/30,Pathogenic,Optic atrophy 1,splice_donor_variant,25.7,\N,\N,OPA1
607761,3:193333561:T>G,NM_130837.2:c.448+2T>G,\N,\N,3/30,Pathogenic,Optic atrophy 1,splice_donor_variant,25.6,\N,\N,OPA1
607762,3:193333574:C>T,NM_130837.2:c.448+15C>T,\N,\N,3/30,Unknown significance,\N,intron_variant,15.48,0.0000863707,EXAC_AMR_AF,OPA1
607763,3:193333576:T>C,NM_130837.2:c.448+17T>C,\N,\N,3/30,Unknown significance,\N,intron_variant,13.8,0.000172741,EXAC_AMR_AF,OPA1
607764,3:193333598:C>G,NM_130837.2:c.448+39C>G,\N,\N,3/30,Unknown significance,\N,intron_variant,0.968,0.0000863707,EXAC_AMR_AF,OPA1
607765,3:193333600:C>T,NM_130837.2:c.448+41C>T,\N,\N,3/30,Unknown significance,\N,intron_variant,3.438,0.0000149894,EXAC_NFE_AF,OPA1
607766,3:193333601:G>A,NM_130837.2:c.448+42G>A,\N,\N,3/30,Unknown significance,\N,intron_variant,2.045,0.00115554,EXAC_EAS_AF,OPA1
607767,3:193333609:A>G,NM_130837.2:c.448+50A>G,\N,\N,3/30,Benign,\N,intron_variant,1.777,0.0378,1KG_SAS_AF,OPA1
607768,3:193333611:A>C,NM_130837.2:c.448+52A>C,\N,\N,3/30,Unknown significance,\N,intron_variant,0.389,0.001,1KG_SAS_AF,OPA1
607769,3:193333654:A>G,NM_130837.2:c.448+95A>G,\N,\N,3/30,Unknown significance,\N,intron_variant,1.135,0.0029,1KG_AMR_AF,OPA1
607770,3:193333659:G>A,NM_130837.2:c.448+100G>A,\N,\N,3/30,Unknown significance,\N,intron_variant,0.477,\N,\N,OPA1
607771,3:193333663:T>A,NM_130837.2:c.448+104T>A,\N,\N,3/30,Unknown significance,\N,intron_variant,10.44,0.0008,1KG_AFR_AF,OPA1
607772,3:193333677:T>G,NM_130837.2:c.448+118T>G,\N,\N,3/30,Unknown significance,\N,intron_variant,1.161,0.0008,1KG_AFR_AF,OPA1
607773,3:193333761:T>C,NM_130837.2:c.448+202T>C,\N,\N,3/30,Unknown significance,\N,intron_variant,1.112,\N,\N,OPA1
607774,3:193333818:C>T,NM_130837.2:c.448+259C>T,\N,\N,3/30,Unknown significance,\N,intron_variant,0.062,\N,\N,OPA1
607775,3:193333819:G>A,NM_130837.2:c.448+260G>A,\N,\N,3/30,Unknown significance,\N,intron_variant,2.192,\N,\N,OPA1
607776,3:193333848:A>G,NM_130837.2:c.448+289A>G,\N,\N,3/30,Unknown significance,\N,intron_variant,2.277,\N,\N,OPA1
607777,3:193333851:C>T,NM_130837.2:c.448+292C>T,\N,\N,3/30,Unknown significance,\N,intron_variant,4.149,\N,\N,OPA1
607778,3:193333859:C>T,NM_130837.2:c.448+300C>T,\N,\N,3/30,Unknown significance,\N,intron_variant,3.199,\N,\N,OPA1
607779,3:193333866:G>T,NM_130837.2:c.448+307G>T,\N,\N,3/30,Unknown significance,\N,intron_variant,2.039,\N,\N,OPA1
607780,3:193333893:C>G,NM_130837.2:c.448+334C>G,\N,\N,3/30,Unknown significance,\N,intron_variant,2.699,0.0029,1KG_AMR_AF,OPA1
607781,3:193333912:C>T,NM_130837.2:c.448+353C>T,\N,\N,3/30,Unknown significance,\N,intron_variant,1.912,\N,\N,OPA1
607782,3:193333913:G>A,NM_130837.2:c.448+354G>A,\N,\N,3/30,Benign,\N,intron_variant,0.833,0.0123,1KG_SAS_AF,OPA1
607783,3:193333933:C>T,NM_130837.2:c.448+374C>T,\N,\N,3/30,Unknown significance,\N,intron_variant,1.372,0.003,1KG_EAS_AF,OPA1
607784,3:193333934:G>A,NM_130837.2:c.448+375G>A,\N,\N,3/30,Unknown significance,\N,intron_variant,2.818,0.002,1KG_EAS_AF,OPA1
607785,3:193333961:C>T,NM_130837.2:c.448+402C>T,\N,\N,3/30,Benign,\N,intron_variant,0.098,0.006,1KG_EUR_AF,OPA1
607786,3:193333981:T>C,NM_130837.2:c.448+422T>C,\N,\N,3/30,Benign,\N,intron_variant,2.371,0.0179,1KG_EAS_AF,OPA1
607787,3:193334001:A>C,NM_130837.2:c.448+442A>C,\N,\N,3/30,Unknown significance,\N,intron_variant,0.183,\N,\N,OPA1
607788,3:193334001:A>G,NM_130837.2:c.448+442A>G,\N,\N,3/30,Unknown significance,\N,intron_variant,0.516,0.001,1KG_EAS_AF,OPA1
607789,3:193334053:T>G,NM_130837.2:c.448+494T>G,\N,\N,3/30,Unknown significance,\N,intron_variant,3.472,0.001,1KG_EAS_AF,OPA1
607790,3:193334054:C>T,NM_130837.2:c.448+495C>T,\N,\N,3/30,Unknown significance,\N,intron_variant,0.639,0.0041,1KG_SAS_AF,OPA1
607791,3:193334056:C>G,NM_130837.2:c.448+497C>G,\N,\N,3/30,Unknown significance,\N,intron_variant,1.786,\N,\N,OPA1
607792,3:193334060:G>A,NM_130837.2:c.448+501G>A,\N,\N,3/30,Benign,\N,intron_variant,3.102,0.0076,1KG_AFR_AF,OPA1
607793,3:193334088:T>C,NM_130837.2:c.448+529T>C,\N,\N,3/30,Unknown significance,\N,intron_variant,0.114,0.001,1KG_EUR_AF,OPA1
607794,3:193334096:T>G,NM_130837.2:c.448+537T>G,\N,\N,3/30,Unknown significance,\N,intron_variant,3.436,\N,\N,OPA1
607795,3:193334100:G>GT,NM_130837.2:c.448+548dup,\N,\N,3/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
607796,3:193334108:C>T,NM_130837.2:c.448+549C>T,\N,\N,3/30,Unknown significance,\N,intron_variant,5.364,\N,\N,OPA1
607797,3:193334132:A>G,NM_130837.2:c.448+573A>G,\N,\N,3/30,Unknown significance,\N,intron_variant,3.694,\N,\N,OPA1
607798,3:193334159:C>G,NM_130837.2:c.448+600C>G,\N,\N,3/30,Unknown significance,\N,intron_variant,9.147,\N,\N,OPA1
607799,3:193334182:A>G,NM_130837.2:c.448+623A>G,\N,\N,3/30,Unknown significance,\N,intron_variant,3.849,0.0008,1KG_AFR_AF,OPA1
607800,3:193334210:C>G,NM_130837.2:c.448+651C>G,\N,\N,3/30,Unknown significance,\N,intron_variant,0.888,0.001,1KG_EAS_AF,OPA1
607801,3:193334252:A>C,NM_130837.2:c.448+693A>C,\N,\N,3/30,Unknown significance,\N,intron_variant,15.48,\N,\N,OPA1
607802,3:193334254:G>A,NM_130837.2:c.448+695G>A,\N,\N,3/30,Unknown significance,\N,intron_variant,17.34,\N,\N,OPA1
607803,3:193334286:A>G,NM_130837.2:c.449-681A>G,\N,\N,3/30,Unknown significance,\N,intron_variant,1.818,\N,\N,OPA1
607804,3:193334333:G>A,NM_130837.2:c.449-634G>A,\N,\N,3/30,Benign,\N,intron_variant,3.803,0.0367,1KG_EAS_AF,OPA1
607805,3:193334401:A>G,NM_130837.2:c.449-566A>G,\N,\N,3/30,Unknown significance,\N,intron_variant,4.118,0.001,1KG_EAS_AF,OPA1
607806,3:193334409:T>C,NM_130837.2:c.449-558T>C,\N,\N,3/30,Benign,\N,intron_variant,5.474,0.1051,1KG_AFR_AF,OPA1
607807,3:193334424:G>T,NM_130837.2:c.449-543G>T,\N,\N,3/30,Unknown significance,\N,intron_variant,0.626,\N,\N,OPA1
607808,3:193334474:T>G,NM_130837.2:c.449-493T>G,\N,\N,3/30,Unknown significance,\N,intron_variant,6.322,0.0029,1KG_AMR_AF,OPA1
607809,3:193334479:C>T,NM_130837.2:c.449-488C>T,\N,\N,3/30,Unknown significance,\N,intron_variant,1.79,0.001,1KG_EUR_AF,OPA1
607810,3:193334480:G>A,NM_130837.2:c.449-487G>A,\N,\N,3/30,Unknown significance,\N,intron_variant,3.654,\N,\N,OPA1
607811,3:193334483:A>G,NM_130837.2:c.449-484A>G,\N,\N,3/30,Unknown significance,\N,intron_variant,2.021,\N,\N,OPA1
607812,3:193334553:G>C,NM_130837.2:c.449-414G>C,\N,\N,3/30,Unknown significance,\N,intron_variant,0.781,0.002,1KG_EUR_AF,OPA1
607813,3:193334593:A>T,NM_130837.2:c.449-374A>T,\N,\N,3/30,Benign,\N,intron_variant,2.027,0.68,1KG_AFR_AF,OPA1
607814,3:193334637:A>G,NM_130837.2:c.449-330A>G,\N,\N,3/30,Unknown significance,\N,intron_variant,0.076,0.001,1KG_EAS_AF,OPA1
607815,3:193334644:C>T,NM_130837.2:c.449-323C>T,\N,\N,3/30,Unknown significance,\N,intron_variant,4.55,0.001,1KG_SAS_AF,OPA1
607816,3:193334645:G>A,NM_130837.2:c.449-322G>A,\N,\N,3/30,Unknown significance,\N,intron_variant,1.479,\N,\N,OPA1
607817,3:193334654:T>C,NM_130837.2:c.449-313T>C,\N,\N,3/30,Unknown significance,\N,intron_variant,3.965,0.0008,1KG_AFR_AF,OPA1
607818,3:193334664:G>A,NM_130837.2:c.449-303G>A,\N,\N,3/30,Unknown significance,\N,intron_variant,5.95,0.002,1KG_SAS_AF,OPA1
607819,3:193334699:G>A,NM_130837.2:c.449-268G>A,\N,\N,3/30,Unknown significance,\N,intron_variant,12.3,0.0014,1KG_AMR_AF,OPA1
607820,3:193334702:A>G,NM_130837.2:c.449-265A>G,\N,\N,3/30,Unknown significance,\N,intron_variant,13.07,\N,\N,OPA1
607821,3:193334712:T>C,NM_130837.2:c.449-255T>C,\N,\N,3/30,Unknown significance,\N,intron_variant,4.719,\N,\N,OPA1
607822,3:193334737:G>C,NM_130837.2:c.449-230G>C,\N,\N,3/30,Benign,\N,intron_variant,0.177,0.0058,1KG_AMR_AF,OPA1
607823,3:193334742:G>A,NM_130837.2:c.449-225G>A,\N,\N,3/30,Unknown significance,\N,intron_variant,3.056,0.0008,1KG_AFR_AF,OPA1
607824,3:193334764:G>C,NM_130837.2:c.449-203G>C,\N,\N,3/30,Unknown significance,\N,intron_variant,0.729,0.0041,1KG_SAS_AF,OPA1
607825,3:193334772:G>A,NM_130837.2:c.449-195G>A,\N,\N,3/30,Unknown significance,\N,intron_variant,2.755,\N,\N,OPA1
607826,3:193334788:G>A,NM_130837.2:c.449-179G>A,\N,\N,3/30,Unknown significance,\N,intron_variant,0.396,0.001,1KG_EUR_AF,OPA1
607827,3:193334799:C>A,NM_130837.2:c.449-168C>A,\N,\N,3/30,Unknown significance,\N,intron_variant,2.293,0.002,1KG_EUR_AF,OPA1
607828,3:193334807:CTG>C,NM_130837.2:c.449-156_449-155del,\N,\N,3/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
607829,3:193334809:G>C,NM_130837.2:c.449-158G>C,\N,\N,3/30,Unknown significance,\N,intron_variant,2.373,0.001,1KG_EAS_AF,OPA1
607830,3:193334846:A>G,NM_130837.2:c.449-121A>G,\N,\N,3/30,Benign,\N,intron_variant,1.234,0.4284,1KG_EUR_AF,OPA1
607831,3:193334847:T>C,NM_130837.2:c.449-120T>C,\N,\N,3/30,Unknown significance,\N,intron_variant,2.147,0.001,1KG_EAS_AF,OPA1
607832,3:193334855:G>A,NM_130837.2:c.449-112G>A,\N,\N,3/30,Unknown significance,\N,intron_variant,0.98,\N,\N,OPA1
607833,3:193334864:G>A,NM_130837.2:c.449-103G>A,\N,\N,3/30,Unknown significance,\N,intron_variant,4.205,\N,\N,OPA1
607834,3:193334869:T>C,NM_130837.2:c.449-98T>C,\N,\N,3/30,Unknown significance,\N,intron_variant,2.176,\N,\N,OPA1
607835,3:193334876:G>T,NM_130837.2:c.449-91G>T,\N,\N,3/30,Unknown significance,\N,intron_variant,1.23,\N,\N,OPA1
607836,3:193334933:A>G,NM_130837.2:c.449-34A>G,\N,\N,3/30,Unknown significance,\N,intron_variant,7.179,0.0000155773,EXAC_NFE_AF,OPA1
607837,3:193334935:T>G,NM_130837.2:c.449-32T>G,\N,\N,3/30,Unknown significance,\N,intron_variant,5.947,0.0000614024,EXAC_SAS_AF,OPA1
607838,3:193334938:C>A,NM_130837.2:c.449-29C>A,\N,\N,3/30,Unknown significance,\N,intron_variant,1.986,0.000116387,EVS_EA_AF,OPA1
607839,3:193334939:A>G,NM_130837.2:c.449-28A>G,\N,\N,3/30,Unknown significance,\N,intron_variant,2.322,0.002,1KG_EUR_AF,OPA1
607840,3:193334940:T>C,NM_130837.2:c.449-27T>C,\N,\N,3/30,Unknown significance,\N,intron_variant,0.047,0.000490918,EXAC_SAS_AF,OPA1
607841,3:193334944:C>G,NM_130837.2:c.449-23C>G,\N,\N,3/30,Unknown significance,\N,intron_variant,2.545,0.001,1KG_EUR_AF,OPA1
607842,3:193334944:C>T,NM_130837.2:c.449-23C>T,\N,\N,3/30,Unknown significance,\N,intron_variant,3.363,0.00223214,EXAC_OTH_AF,OPA1
607843,3:193334946:A>G,NM_130837.2:c.449-21A>G,\N,\N,3/30,Benign,\N,intron_variant,4.091,0.1051,1KG_AFR_AF,OPA1
607844,3:193334948:A>G,NM_130837.2:c.449-19A>G,\N,\N,3/30,Unknown significance,\N,intron_variant,5.667,0.000262284,EXAC_AMR_AF,OPA1
607845,3:193334975:A>G,NM_130837.2:c.457A>G,NP_570850.2:p.Arg153Gly,4/31,\N,Unknown significance,\N,missense_variant,18.17,0.000030077,EXAC_NFE_AF,OPA1
607846,3:193334976:G>A,NM_130837.2:c.458G>A,NP_570850.2:p.Arg153Lys,4/31,\N,Unknown significance,\N,missense_variant,11.22,0.000232072,EXAC_EAS_AF,OPA1
607847,3:193334982:C>T,NM_130837.2:c.464C>T,NP_570850.2:p.Ala155Val,4/31,\N,Unknown significance,\N,missense_variant,23,0.0000865651,EXAC_AMR_AF,OPA1
607848,3:193334991:G>A,NM_130837.2:c.473G>A,NP_570850.2:p.Ser158Asn,4/31,\N,Benign,\N,missense_variant,17.44,0.5847,1KG_AFR_AF,OPA1
607849,3:193335007:A>G,NM_130837.2:c.489A>G,NP_570850.2:p.Val163=,4/31,\N,Unknown significance,\N,synonymous_variant,9.667,0.001,1KG_SAS_AF,OPA1
607850,3:193335018:C>G,NM_130837.2:c.500C>G,NP_570850.2:p.Pro167Arg,4/31,\N,Unknown significance,\N,missense_variant,18.51,0.0000150033,EXAC_NFE_AF,OPA1
607851,3:193335023:TTTG>T,NM_130837.2:c.506_508del,NP_570850.2:p.Phe169_Asp170delinsTyr,4/31,\N,Unknown significance,\N,inframe_deletion,22.5,0.000302572,EXAC_FIN_AF,OPA1
607852,3:193335032:A>C,NM_130837.2:c.514A>C,NP_570850.2:p.Ile172Leu,4/31,\N,Unknown significance,\N,missense_variant,7.108,0.0000150119,EXAC_NFE_AF,OPA1
607853,3:193335034:T>G,NM_130837.2:c.516T>G,NP_570850.2:p.Ile172Met,4/31,\N,Unknown significance,\N,missense_variant,7.882,\N,\N,OPA1
607854,3:193335035:G>A,NM_130837.2:c.517G>A,NP_570850.2:p.Val173Ile,4/31,\N,Likely benign,\N,missense_variant,13.43,0.000606281,EXAC_SAS_AF,OPA1
607855,3:193335048:G>T,NM_130837.2:c.530G>T,NP_570850.2:p.Ser177Ile,4/31,\N,Unknown significance,\N,missense_variant,14.22,0.000581666,EVS_EA_AF,OPA1
607856,3:193335049:C>A,NM_130837.2:c.531C>A,NP_570850.2:p.Ser177Arg,4/31,\N,Unknown significance,\N,missense_variant,19.35,\N,\N,OPA1
607857,3:193335049:CTT>ATA,NM_130837.2:c.531_533delinsATA,NP_570850.2:p.Ser177_Leu178delinsArgTer,4/31,\N,Pathogenic,\N,stop_gained,\N,\N,\N,OPA1
607858,3:193335051:T>A,NM_130837.2:c.533T>A,NP_570850.2:p.Leu178Ter,4/31,\N,Pathogenic,Dominant hereditary optic atrophy,stop_gained,36,\N,\N,OPA1
607859,3:193335052:A>G,NM_130837.2:c.534A>G,NP_570850.2:p.Leu178=,4/31,\N,Unknown significance,\N,synonymous_variant,9.875,0.0000301132,EXAC_NFE_AF,OPA1
607860,3:193335057:A>G,NM_130837.2:c.539A>G,NP_570850.2:p.Lys180Arg,4/31,\N,Unknown significance,\N,missense_variant,21.1,0.00011636,EXAC_EAS_AF,OPA1
607861,3:193335058:G>A,NM_130837.2:c.540G>A,NP_570850.2:p.Lys180=,4/31,\N,Unknown significance,\N,synonymous_variant,11.87,0.000196194,EXAC_AFR_AF,OPA1
607862,3:193335058:G>T,NM_130834.2:c.540G>T,NP_570847.2:p.Lys180Asn,4/30,\N,Unknown significance,\N,missense_variant,20.3,0.0000607829,EXAC_SAS_AF,OPA1
607863,3:193335059:G>C,NM_130836.2:c.541G>C,NP_570849.2:p.Asp181His,4/30,\N,Unknown significance,\N,missense_variant,20.8,0.0000151016,EXAC_NFE_AF,OPA1
607864,3:193335060:A>G,NM_130837.2:c.542A>G,NP_570850.2:p.Asp181Gly,4/31,\N,Unknown significance,\N,missense_variant,18.26,0.000116333,EVS_EA_AF,OPA1
607865,3:193335062:T>C,NM_130837.2:c.544T>C,NP_570850.2:p.Phe182Leu,4/31,\N,Likely benign,\N,missense_variant,10.42,0.000121699,EXAC_SAS_AF,OPA1
607866,3:193335066:T>C,NM_130837.2:c.548T>C,NP_570850.2:p.Phe183Ser,4/31,\N,Unknown significance,\N,missense_variant,22,0.000117398,EXAC_EAS_AF,OPA1
607867,3:193335070:C>G,NM_130837.2:c.552C>G,NP_570850.2:p.Thr184=,4/31,\N,Unknown significance,\N,synonymous_variant,12.91,\N,\N,OPA1
607868,3:193335076:T>G,NM_130837.2:c.556+2T>G,\N,\N,4/30,Unknown significance,\N,splice_donor_variant,26.1,0.000119446,EXAC_EAS_AF,OPA1
607869,3:193335080:G>A,NM_130837.2:c.556+6G>A,\N,\N,4/30,Unknown significance,\N,splice_region_variant&intron_variant,10.92,0.0000156187,EXAC_NFE_AF,OPA1
607870,3:193335086:G>A,NM_130837.2:c.556+12G>A,\N,\N,4/30,Unknown significance,\N,intron_variant,3.644,0.000187079,EXAC_SAS_AF,OPA1
607871,3:193335086:G>T,NM_130837.2:c.556+12G>T,\N,\N,4/30,Unknown significance,\N,intron_variant,1.234,0.000116387,EVS_EA_AF,OPA1
607872,3:193335088:T>C,NM_130837.2:c.556+14T>C,\N,\N,4/30,Unknown significance,\N,intron_variant,5.018,0.000227169,EVS_AA_AF,OPA1
607873,3:193335093:G>A,NM_130837.2:c.556+19G>A,\N,\N,4/30,Unknown significance,\N,intron_variant,6.184,0.00244656,EXAC_EAS_AF,OPA1
607874,3:193335096:C>G,NM_130837.2:c.556+22C>G,\N,\N,4/30,Unknown significance,\N,intron_variant,0.415,0.0008,1KG_AFR_AF,OPA1
607875,3:193335100:T>C,NM_130837.2:c.556+26T>C,\N,\N,4/30,Unknown significance,\N,intron_variant,3.781,\N,\N,OPA1
607876,3:193335105:A>C,NM_130837.2:c.556+31A>C,\N,\N,4/30,Unknown significance,\N,intron_variant,1.029,\N,\N,OPA1
607877,3:193335106:A>C,NM_130837.2:c.556+32A>C,\N,\N,4/30,Unknown significance,\N,intron_variant,0.63,0.0000168163,EXAC_NFE_AF,OPA1
607878,3:193335106:A>T,NM_130837.2:c.556+32A>T,\N,\N,4/30,Unknown significance,\N,intron_variant,0.926,0.0000635163,EXAC_SAS_AF,OPA1
607879,3:193335116:C>A,NM_130837.2:c.556+42C>A,\N,\N,4/30,Unknown significance,\N,intron_variant,6.966,0.0000350447,EXAC_NFE_AF,OPA1
607880,3:193335116:C>G,NM_130837.2:c.556+42C>G,\N,\N,4/30,Unknown significance,\N,intron_variant,5.277,0.002,1KG_SAS_AF,OPA1
607881,3:193335133:A>G,NM_130837.2:c.556+59A>G,\N,\N,4/30,Unknown significance,\N,intron_variant,1.785,0.0014,1KG_AMR_AF,OPA1
607882,3:193335135:G>A,NM_130837.2:c.556+61G>A,\N,\N,4/30,Benign,\N,intron_variant,2.932,0.0112,1KG_SAS_AF,OPA1
607883,3:193335161:T>A,NM_130837.2:c.556+87T>A,\N,\N,4/30,Unknown significance,\N,intron_variant,7,0.0038,1KG_AFR_AF,OPA1
607884,3:193335162:A>T,NM_130837.2:c.556+88A>T,\N,\N,4/30,Unknown significance,\N,intron_variant,7.988,0.002,1KG_SAS_AF,OPA1
607885,3:193335173:AT>A,NM_130837.2:c.556+102del,\N,\N,4/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
607886,3:193335203:T>C,NM_130837.2:c.556+129T>C,\N,\N,4/30,Unknown significance,\N,intron_variant,0.404,0.001,1KG_EAS_AF,OPA1
607887,3:193335245:T>A,NM_130837.2:c.556+171T>A,\N,\N,4/30,Benign,\N,intron_variant,6.834,0.0189,1KG_AFR_AF,OPA1
607888,3:193335252:G>T,NM_130837.2:c.556+178G>T,\N,\N,4/30,Benign,\N,intron_variant,2.473,0.584,1KG_AFR_AF,OPA1
607889,3:193335268:A>G,NM_130837.2:c.556+194A>G,\N,\N,4/30,Unknown significance,\N,intron_variant,2.972,0.0008,1KG_AFR_AF,OPA1
607890,3:193335286:A>C,NM_130837.2:c.556+212A>C,\N,\N,4/30,Unknown significance,\N,intron_variant,3.693,0.001,1KG_EAS_AF,OPA1
607891,3:193335371:A>G,NM_130837.2:c.557-202A>G,\N,\N,4/30,Unknown significance,\N,intron_variant,13.23,\N,\N,OPA1
607892,3:193335424:T>C,NM_130837.2:c.557-149T>C,\N,\N,4/30,Benign,\N,intron_variant,5.756,0.0179,1KG_EAS_AF,OPA1
607893,3:193335432:A>G,NM_130837.2:c.557-141A>G,\N,\N,4/30,Unknown significance,\N,intron_variant,8.304,0.0038,1KG_AFR_AF,OPA1
607894,3:193335482:G>A,NM_130837.2:c.557-91G>A,\N,\N,4/30,Unknown significance,\N,intron_variant,1.554,0.002,1KG_SAS_AF,OPA1
607895,3:193335483:T>C,NM_130837.2:c.557-90T>C,\N,\N,4/30,Unknown significance,\N,intron_variant,4.508,0.0008,1KG_AFR_AF,OPA1
607896,3:193335528:G>T,NM_130837.2:c.557-45G>T,\N,\N,4/30,Unknown significance,\N,intron_variant,15.41,0.0000886368,EXAC_AMR_AF,OPA1
607897,3:193335532:A>T,NM_130837.2:c.557-41A>T,\N,\N,4/30,Unknown significance,\N,intron_variant,17.75,0.0000991277,EXAC_AFR_AF,OPA1
607898,3:193335540:A>T,NM_130837.2:c.557-33A>T,\N,\N,4/30,Unknown significance,\N,intron_variant,16.67,0.000116279,EVS_EA_AF,OPA1
607899,3:193335545:T>A,NM_130837.2:c.557-28T>A,\N,\N,4/30,Unknown significance,\N,intron_variant,19.68,0.000015345,EXAC_NFE_AF,OPA1
607900,3:193335561:G>C,NM_130837.2:c.557-12G>C,\N,\N,4/30,Unknown significance,\N,intron_variant,17.11,0.000226963,EVS_AA_AF,OPA1
607901,3:193335562:A>G,NM_130837.2:c.557-11A>G,\N,\N,4/30,Unknown significance,\N,intron_variant,15.73,0.000226963,EVS_AA_AF,OPA1
607902,3:193335568:C>T,NM_130837.2:c.557-5C>T,\N,\N,4/30,Unknown significance,\N,splice_region_variant&intron_variant,20.8,0.0000755858,EXAC_NFE_AF,OPA1
607903,3:193335573:G>A,NM_130835.2:c.449G>A,NP_570848.1:p.Gly150Asp,4/30,\N,Unknown significance,\N,missense_variant&splice_region_variant,21.8,0.0000971251,EXAC_AFR_AF,OPA1
607904,3:193335575:C>T,NM_130837.2:c.559C>T,NP_570850.2:p.His187Tyr,5/31,\N,Likely benign,\N,missense_variant&splice_region_variant,20.4,0.000116279,EVS_EA_AF,OPA1
607905,3:193335588:G>C,NM_130837.2:c.572G>C,NP_570850.2:p.Ser191Thr,5/31,\N,Unknown significance,\N,missense_variant,19.44,0.000302572,EXAC_FIN_AF,OPA1
607906,3:193335596:A>G,NM_130837.2:c.580A>G,NP_570850.2:p.Ile194Val,5/31,\N,Likely benign,\N,missense_variant,19.75,0.000116279,EVS_EA_AF,OPA1
607907,3:193335608:G>A,NM_130837.2:c.592G>A,NP_570850.2:p.Asp198Asn,5/31,\N,Unknown significance,\N,missense_variant,21.5,0.0000150611,EXAC_NFE_AF,OPA1
607908,3:193335614:C>T,NM_130837.2:c.598C>T,NP_570850.2:p.Leu200Phe,5/31,\N,Unknown significance,\N,missense_variant,21.9,0.0000613346,EXAC_SAS_AF,OPA1
607909,3:193335619:C>T,NM_130837.2:c.603C>T,NP_570850.2:p.Leu201=,5/31,\N,Unknown significance,\N,synonymous_variant,21,0.000261506,EXAC_AMR_AF,OPA1
607910,3:193335629:G>A,NM_130837.2:c.610+3G>A,\N,\N,5/30,Unknown significance,\N,splice_region_variant&intron_variant,21.5,0.0000151658,EXAC_NFE_AF,OPA1
607911,3:193335629:G>T,NM_130837.2:c.610+3G>T,\N,\N,5/30,Unknown significance,\N,splice_region_variant&intron_variant,20.5,0.0000454973,EXAC_NFE_AF,OPA1
607912,3:193335630:T>C,NM_130837.2:c.610+4T>C,\N,\N,5/30,Unknown significance,\N,splice_region_variant&intron_variant,20.4,0.0000151676,EXAC_NFE_AF,OPA1
607913,3:193335636:CAG>C,NM_130837.2:c.610+12_610+13del,\N,\N,5/30,Unknown significance,\N,intron_variant,22.3,0.000151791,EXAC_FIN_AF,OPA1
607914,3:193335637:A>C,NM_130837.2:c.610+11A>C,\N,\N,5/30,Unknown significance,\N,intron_variant,16.78,0.0000152397,EXAC_NFE_AF,OPA1
607915,3:193335659:A>T,NM_130837.2:c.610+33A>T,\N,\N,5/30,Benign,\N,intron_variant,17.08,0.0151,1KG_AFR_AF,OPA1
607916,3:193335670:A>C,NM_130837.2:c.610+44A>C,\N,\N,5/30,Unknown significance,\N,intron_variant,16.64,0.0008,1KG_AFR_AF,OPA1
607917,3:193335675:TCTAATAAA>T,NM_130837.2:c.610+53_610+60del,\N,\N,5/30,Unknown significance,\N,intron_variant,22.8,\N,\N,OPA1
607918,3:193335676:C>A,NM_130837.2:c.610+50C>A,\N,\N,5/30,Unknown significance,\N,intron_variant,20.5,0.00181653,EVS_AA_AF,OPA1
607919,3:193335707:C>T,NM_130837.2:c.610+81C>T,\N,\N,5/30,Unknown significance,\N,intron_variant,20.6,\N,\N,OPA1
607920,3:193335728:T>C,NM_130837.2:c.610+102T>C,\N,\N,5/30,Unknown significance,\N,intron_variant,15.88,0.0014,1KG_AMR_AF,OPA1
607921,3:193335753:A>G,NM_130837.2:c.610+127A>G,\N,\N,5/30,Benign,\N,intron_variant,12,0.006,1KG_EUR_AF,OPA1
607922,3:193335767:CATT>C,NM_130837.2:c.610+144_610+146del,\N,\N,5/30,Unknown significance,\N,intron_variant,15.33,0.0031,1KG_SAS_AF,OPA1
607923,3:193335801:T>C,NM_130837.2:c.610+175T>C,\N,\N,5/30,Unknown significance,\N,intron_variant,13.76,\N,\N,OPA1
607924,3:193335831:G>T,NM_130837.2:c.610+205G>T,\N,\N,5/30,Unknown significance,\N,intron_variant,6.667,\N,\N,OPA1
607925,3:193335872:C>T,NM_130837.2:c.610+246C>T,\N,\N,5/30,Unknown significance,\N,intron_variant,8.131,0.0045,1KG_AFR_AF,OPA1
607926,3:193335939:G>T,NM_130837.2:c.610+313G>T,\N,\N,5/30,Unknown significance,\N,intron_variant,18.31,\N,\N,OPA1
607927,3:193335948:A>G,NM_130837.2:c.610+322A>G,\N,\N,5/30,Unknown significance,\N,intron_variant,19.51,\N,\N,OPA1
607928,3:193335950:C>G,NM_130837.2:c.610+324C>G,\N,\N,5/30,Unknown significance,\N,intron_variant,18.9,0.002,1KG_EAS_AF,OPA1
607929,3:193335952:G>T,NM_130837.2:c.610+326G>T,\N,\N,5/30,Unknown significance,\N,intron_variant,18.61,\N,\N,OPA1
607930,3:193335986:G>A,NM_130837.2:c.610+360G>A,\N,\N,5/30,Pathogenic,Optic atrophy 1,intron_variant,0.903,\N,\N,OPA1
607931,3:193335989:C>T,NM_130837.2:c.610+363C>T,\N,\N,5/30,Unknown significance,\N,intron_variant,1.64,0.001,1KG_EAS_AF,OPA1
607932,3:193335990:G>A,NM_130837.2:c.610+364G>A,\N,\N,5/30,Pathogenic,Optic atrophy 1,intron_variant,1.147,\N,\N,OPA1
607933,3:193335994:G>A,NM_130837.2:c.610+368G>A,\N,\N,5/30,Unknown significance,\N,intron_variant,1.968,\N,\N,OPA1
607934,3:193335996:G>A,NM_130837.2:c.610+370G>A,\N,\N,5/30,Unknown significance,\N,intron_variant,0.664,0.0014,1KG_AMR_AF,OPA1
607935,3:193336021:A>G,NM_130837.2:c.610+395A>G,\N,\N,5/30,Unknown significance,\N,intron_variant,4.891,0.001,1KG_EUR_AF,OPA1
607936,3:193336024:T>C,NM_130837.2:c.610+398T>C,\N,\N,5/30,Unknown significance,\N,intron_variant,3.902,0.001,1KG_EAS_AF,OPA1
607937,3:193336035:A>G,NM_130837.2:c.610+409A>G,\N,\N,5/30,Benign,\N,intron_variant,0.259,0.3224,1KG_EAS_AF,OPA1
607938,3:193336042:C>T,NM_130837.2:c.610+416C>T,\N,\N,5/30,Unknown significance,\N,intron_variant,0.557,\N,\N,OPA1
607939,3:193336056:A>G,NM_130837.2:c.610+430A>G,\N,\N,5/30,Unknown significance,\N,intron_variant,2.191,0.0014,1KG_AMR_AF,OPA1
607940,3:193336064:G>A,NM_130837.2:c.610+438G>A,\N,\N,5/30,Unknown significance,\N,intron_variant,1.624,\N,\N,OPA1
607941,3:193336123:C>T,NM_130837.2:c.610+497C>T,\N,\N,5/30,Unknown significance,\N,intron_variant,3.054,0.0045,1KG_AFR_AF,OPA1
607942,3:193336124:G>A,NM_130837.2:c.610+498G>A,\N,\N,5/30,Unknown significance,\N,intron_variant,0.299,\N,\N,OPA1
607943,3:193336128:G>A,NM_130837.2:c.610+502G>A,\N,\N,5/30,Benign,\N,intron_variant,0.633,0.0083,1KG_AFR_AF,OPA1
607944,3:193336130:G>A,NM_130837.2:c.610+504G>A,\N,\N,5/30,Unknown significance,\N,intron_variant,3.217,\N,\N,OPA1
607945,3:193336140:G>A,NM_130837.2:c.610+514G>A,\N,\N,5/30,Unknown significance,\N,intron_variant,0.405,\N,\N,OPA1
607946,3:193336160:G>A,NM_130837.2:c.611-498G>A,\N,\N,5/30,Unknown significance,\N,intron_variant,0.243,\N,\N,OPA1
607947,3:193336199:G>A,NM_130837.2:c.611-459G>A,\N,\N,5/30,Unknown significance,\N,intron_variant,1.78,0.0023,1KG_AFR_AF,OPA1
607948,3:193336222:G>A,NM_130837.2:c.611-436G>A,\N,\N,5/30,Benign,\N,intron_variant,1.338,0.3211,1KG_SAS_AF,OPA1
607949,3:193336223:C>T,NM_130837.2:c.611-435C>T,\N,\N,5/30,Unknown significance,\N,intron_variant,0.222,0.0014,1KG_AMR_AF,OPA1
607950,3:193336227:A>G,NM_130837.2:c.611-431A>G,\N,\N,5/30,Unknown significance,\N,intron_variant,0.156,0.001,1KG_SAS_AF,OPA1
607951,3:193336245:C>T,NM_130837.2:c.611-413C>T,\N,\N,5/30,Unknown significance,\N,intron_variant,0.327,\N,\N,OPA1
607952,3:193336252:G>A,NM_130837.2:c.611-406G>A,\N,\N,5/30,Unknown significance,\N,intron_variant,1.861,0.001,1KG_SAS_AF,OPA1
607953,3:193336269:A>AC,NM_130837.2:c.611-384dup,\N,\N,5/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
607954,3:193336275:A>C,NM_130837.2:c.611-383A>C,\N,\N,5/30,Benign,\N,intron_variant,0.618,0.1006,1KG_AFR_AF,OPA1
607955,3:193336286:G>A,NM_130837.2:c.611-372G>A,\N,\N,5/30,Unknown significance,\N,intron_variant,1.681,\N,\N,OPA1
607956,3:193336287:A>G,NM_130837.2:c.611-371A>G,\N,\N,5/30,Unknown significance,\N,intron_variant,0.502,0.001,1KG_SAS_AF,OPA1
607957,3:193336291:G>A,NM_130837.2:c.611-367G>A,\N,\N,5/30,Benign,\N,intron_variant,0.17,0.0101,1KG_AMR_AF,OPA1
607958,3:193336420:T>C,NM_130837.2:c.611-238T>C,\N,\N,5/30,Unknown significance,\N,intron_variant,3.247,0.001,1KG_EAS_AF,OPA1
607959,3:193336425:T>C,NM_130837.2:c.611-233T>C,\N,\N,5/30,Benign,\N,intron_variant,3.968,0.4284,1KG_EUR_AF,OPA1
607960,3:193336428:T>A,NM_130837.2:c.611-230T>A,\N,\N,5/30,Unknown significance,\N,intron_variant,3.778,\N,\N,OPA1
607961,3:193336433:G>A,NM_130837.2:c.611-225G>A,\N,\N,5/30,Unknown significance,\N,intron_variant,5.143,0.003,1KG_EAS_AF,OPA1
607962,3:193336437:G>A,NM_130837.2:c.611-221G>A,\N,\N,5/30,Unknown significance,\N,intron_variant,10.61,\N,\N,OPA1
607963,3:193336461:A>G,NM_130837.2:c.611-197A>G,\N,\N,5/30,Unknown significance,\N,intron_variant,4.117,0.0008,1KG_AFR_AF,OPA1
607964,3:193336461:ATAGT>A,NM_130837.2:c.611-191_611-188del,\N,\N,5/30,Unknown significance,\N,intron_variant,8.588,\N,\N,OPA1
607965,3:193336468:G>GT,NM_130837.2:c.611-180dup,\N,\N,5/30,Benign,\N,intron_variant,2.198,0.0123,1KG_SAS_AF,OPA1
607966,3:193336468:GT>G,NM_130837.2:c.611-180del,\N,\N,5/30,Unknown significance,\N,intron_variant,3.908,\N,\N,OPA1
607967,3:193336488:A>G,NM_130837.2:c.611-170A>G,\N,\N,5/30,Unknown significance,\N,intron_variant,4.431,0.001,1KG_SAS_AF,OPA1
607968,3:193336510:T>TA,NM_130837.2:c.611-144dup,\N,\N,5/30,Unknown significance,\N,intron_variant,13.52,\N,\N,OPA1
607969,3:193336539:T>C,NM_130837.2:c.611-119T>C,\N,\N,5/30,Unknown significance,\N,intron_variant,8.077,0.0014,1KG_AMR_AF,OPA1
607970,3:193336551:T>G,NM_130837.2:c.611-107T>G,\N,\N,5/30,Unknown significance,\N,intron_variant,11.08,\N,\N,OPA1
607971,3:193336587:T>C,NM_130837.2:c.611-71T>C,\N,\N,5/30,Unknown significance,\N,intron_variant,0.772,0.0008,1KG_AFR_AF,OPA1
607972,3:193336599:T>G,NM_130837.2:c.611-59T>G,\N,\N,5/30,Unknown significance,\N,intron_variant,7.114,0.001,1KG_SAS_AF,OPA1
607973,3:193336605:T>C,NM_130837.2:c.611-53T>C,\N,\N,5/30,Benign,\N,intron_variant,5.595,0.0102,1KG_SAS_AF,OPA1
607974,3:193336615:G>A,NM_130837.2:c.611-43G>A,\N,\N,5/30,Unknown significance,\N,intron_variant,10.35,0.0008,1KG_AFR_AF,OPA1
607975,3:193336628:A>G,NM_130837.2:c.611-30A>G,\N,\N,5/30,Unknown significance,\N,intron_variant,10.66,0.00008992,EXAC_NFE_AF,OPA1
607976,3:193336629:A>G,NM_130837.2:c.611-29A>G,\N,\N,5/30,Unknown significance,\N,intron_variant,10.23,0.00011566,EXAC_EAS_AF,OPA1
607977,3:193336638:G>A,NM_130837.2:c.611-20G>A,\N,\N,5/30,Unknown significance,\N,intron_variant,8.21,0.0000149853,EXAC_NFE_AF,OPA1
607978,3:193336639:T>C,NM_130837.2:c.611-19T>C,\N,\N,5/30,Benign,\N,intron_variant,4.782,0.528433,EXAC_FIN_AF,OPA1
607979,3:193336643:A>G,NM_130837.2:c.611-15A>G,\N,\N,5/30,Unknown significance,\N,intron_variant,1.291,\N,\N,OPA1
607980,3:193336649:A>G,NM_130837.2:c.611-9A>G,\N,\N,5/30,Unknown significance,\N,intron_variant,11.98,0.000116279,EVS_EA_AF,OPA1
607981,3:193336658:G>C,NM_130837.2:c.611G>C,NP_570850.2:p.Gly204Ala,6/31,\N,Unknown significance,\N,missense_variant&splice_region_variant,11.16,0.000060562,EXAC_SAS_AF,OPA1
607982,3:193336664:C>T,NM_130837.2:c.617C>T,NP_570850.2:p.Pro206Leu,6/31,\N,Likely benign,\N,missense_variant,19.72,0.000346901,EXAC_EAS_AF,OPA1
607983,3:193336665:G>A,NM_130837.2:c.618G>A,NP_570850.2:p.Pro206=,6/31,\N,Unknown significance,\N,synonymous_variant,3.254,0.0000961723,EXAC_AFR_AF,OPA1
607984,3:193336666:G>A,NM_130837.2:c.619G>A,NP_570850.2:p.Glu207Lys,6/31,\N,Likely benign,\N,missense_variant,12.53,0.002,1KG_EAS_AF,OPA1
607985,3:193336666:G>C,NM_130837.2:c.619G>C,NP_570850.2:p.Glu207Gln,6/31,\N,Likely benign,\N,missense_variant,9.051,\N,\N,OPA1
607986,3:193336673:C>T,NM_130837.2:c.626C>T,NP_570850.2:p.Thr209Met,6/31,\N,Unknown significance,\N,missense_variant,22.6,0.0000149849,EXAC_NFE_AF,OPA1
607987,3:193336674:G>A,NM_130837.2:c.627G>A,NP_570850.2:p.Thr209=,6/31,\N,Unknown significance,\N,synonymous_variant,11.35,0.000172771,EXAC_AMR_AF,OPA1
607988,3:193336676:C>T,NM_130833.2:c.467C>T,NP_570846.1:p.Ala156Val,4/29,\N,Benign,\N,missense_variant,22.3,0.0367,1KG_EAS_AF,OPA1
607989,3:193336677:G>A,NM_130837.2:c.630G>A,NP_570850.2:p.Ala210=,6/31,\N,Unknown significance,\N,synonymous_variant,9.042,0.000060562,EXAC_SAS_AF,OPA1
607990,3:193336677:G>GTT,NM_130837.2:c.632_633dup,NP_570850.2:p.Arg212LeufsTer72,6/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,32,\N,\N,OPA1
607991,3:193336679:T>A,NM_130837.2:c.632T>A,NP_570850.2:p.Phe211Tyr,6/31,\N,Unknown significance,\N,missense_variant,10.53,0.000060562,EXAC_SAS_AF,OPA1
607992,3:193336682:G>A,NM_130837.2:c.635G>A,NP_570850.2:p.Arg212Lys,6/31,\N,Unknown significance,\N,missense_variant,9.802,0.0000863856,EXAC_AMR_AF,OPA1
607993,3:193336694:G>A,NM_130837.2:c.647G>A,NP_570850.2:p.Arg216His,6/31,\N,Likely benign,\N,missense_variant,11.91,0.0014,1KG_AMR_AF,OPA1
607994,3:193336700:C>T,NR_046634.1:n.191-1G>A,\N,\N,2/2,Unknown significance,\N,splice_acceptor_variant&non_coding_transcript_variant,22.7,0.000348837,EVS_EA_AF,OPA1
607995,3:193336708:G>A,NM_130837.2:c.661G>A,NP_570850.2:p.Asp221Asn,6/31,\N,Unknown significance,\N,missense_variant,19.85,0.000226963,EVS_AA_AF,OPA1
607996,3:193336732:GTAAAAGAGAA>G,NM_130837.2:c.678+9_678+18del,\N,\N,6/30,Unknown significance,\N,splice_region_variant&intron_variant,10.89,\N,\N,OPA1
607997,3:193336735:A>G,NM_130837.2:c.678+10A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,8.53,0.0000149952,EXAC_NFE_AF,OPA1
607998,3:193336736:A>G,NM_130837.2:c.678+11A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,7.785,0.00068089,EVS_AA_AF,OPA1
607999,3:193336738:G>C,NM_130837.2:c.678+13G>C,\N,\N,6/30,Unknown significance,\N,intron_variant,4.552,0.003,1KG_EAS_AF,OPA1
608000,3:193336742:AT>A,NM_130837.2:c.678+19del,\N,\N,6/30,Unknown significance,\N,intron_variant,5.182,0.0000149988,EXAC_NFE_AF,OPA1
608001,3:193336749:A>G,NM_130837.2:c.678+24A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,5.233,\N,\N,OPA1
608002,3:193336750:T>C,NM_130837.2:c.678+25T>C,\N,\N,6/30,Unknown significance,\N,intron_variant,0.967,\N,\N,OPA1
608003,3:193336753:A>G,NM_130837.2:c.678+28A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,7.588,0.0000150177,EXAC_NFE_AF,OPA1
608004,3:193336754:G>C,NM_130837.2:c.678+29G>C,\N,\N,6/30,Unknown significance,\N,intron_variant,3.036,0.0000150222,EXAC_NFE_AF,OPA1
608005,3:193336757:A>G,NM_130837.2:c.678+32A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,7.719,0.0000605987,EXAC_SAS_AF,OPA1
608006,3:193336766:A>G,NM_130837.2:c.678+41A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,5.408,0.0000150494,EXAC_NFE_AF,OPA1
608007,3:193336768:AT>A,NM_130837.2:c.678+49del,\N,\N,6/30,Unknown significance,\N,intron_variant,6.056,0.0000150543,EXAC_NFE_AF,OPA1
608008,3:193336768:A>G,NM_130837.2:c.678+43A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,6.962,0.000293772,EXAC_AFR_AF,OPA1
608009,3:193336770:T>G,NM_130837.2:c.678+45T>G,\N,\N,6/30,Unknown significance,\N,intron_variant,8.774,0.000860455,EXAC_NFE_AF,OPA1
608010,3:193336771:T>G,NM_130837.2:c.678+46T>G,\N,\N,6/30,Unknown significance,\N,intron_variant,6.953,0.000260688,EXAC_AMR_AF,OPA1
608011,3:193336775:A>G,NM_130837.2:c.678+50A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,4.146,0.000364564,EXAC_SAS_AF,OPA1
608012,3:193336797:A>T,NM_130837.2:c.678+72A>T,\N,\N,6/30,Unknown significance,\N,intron_variant,0.902,\N,\N,OPA1
608013,3:193336852:C>T,NM_130837.2:c.678+127C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,4.889,0.0008,1KG_AFR_AF,OPA1
608014,3:193336853:G>A,NM_130837.2:c.678+128G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,3.767,0.0008,1KG_AFR_AF,OPA1
608015,3:193336859:A>T,NM_130837.2:c.678+134A>T,\N,\N,6/30,Unknown significance,\N,intron_variant,7.928,\N,\N,OPA1
608016,3:193336876:C>A,NM_130837.2:c.678+151C>A,\N,\N,6/30,Unknown significance,\N,intron_variant,4.82,0.002,1KG_SAS_AF,OPA1
608017,3:193336884:T>C,NM_130837.2:c.678+159T>C,\N,\N,6/30,Unknown significance,\N,intron_variant,2.551,\N,\N,OPA1
608018,3:193336886:C>T,NM_130837.2:c.678+161C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,0.218,0.001,1KG_EUR_AF,OPA1
608019,3:193336887:G>A,NM_130837.2:c.678+162G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,2.087,0.001,1KG_EUR_AF,OPA1
608020,3:193336933:T>G,NM_130837.2:c.678+208T>G,\N,\N,6/30,Unknown significance,\N,intron_variant,2.089,0.001,1KG_EAS_AF,OPA1
608021,3:193336938:A>C,NM_130837.2:c.678+213A>C,\N,\N,6/30,Unknown significance,\N,intron_variant,4.078,\N,\N,OPA1
608022,3:193336955:G>A,NM_130837.2:c.678+230G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,4.98,\N,\N,OPA1
608023,3:193336960:T>C,NM_130837.2:c.678+235T>C,\N,\N,6/30,Benign,\N,intron_variant,11,0.0257,1KG_AFR_AF,OPA1
608024,3:193337000:G>A,NM_130837.2:c.678+275G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,2.203,\N,\N,OPA1
608025,3:193337007:G>C,NM_130837.2:c.678+282G>C,\N,\N,6/30,Unknown significance,\N,intron_variant,1.316,0.0015,1KG_AFR_AF,OPA1
608026,3:193337011:G>A,NM_130837.2:c.678+286G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,2.226,\N,\N,OPA1
608027,3:193337014:T>C,NM_130837.2:c.678+289T>C,\N,\N,6/30,Unknown significance,\N,intron_variant,5.076,0.001,1KG_EUR_AF,OPA1
608028,3:193337021:G>A,NM_130837.2:c.678+296G>A,\N,\N,6/30,Benign,\N,intron_variant,5.334,0.584,1KG_AFR_AF,OPA1
608029,3:193337027:C>T,NM_130837.2:c.678+302C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,3.995,\N,\N,OPA1
608030,3:193337043:C>G,NM_130837.2:c.678+318C>G,\N,\N,6/30,Unknown significance,\N,intron_variant,3.173,0.0008,1KG_AFR_AF,OPA1
608031,3:193337046:T>C,NM_130837.2:c.678+321T>C,\N,\N,6/30,Unknown significance,\N,intron_variant,2.374,0.001,1KG_SAS_AF,OPA1
608032,3:193337087:T>C,NM_130837.2:c.678+362T>C,\N,\N,6/30,Unknown significance,\N,intron_variant,5.365,0.0023,1KG_AFR_AF,OPA1
608033,3:193337093:A>G,NM_130837.2:c.678+368A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,5.012,\N,\N,OPA1
608034,3:193337133:A>G,NM_130837.2:c.678+408A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,2.775,\N,\N,OPA1
608035,3:193337140:C>G,NM_130837.2:c.678+415C>G,\N,\N,6/30,Unknown significance,\N,intron_variant,0.773,\N,\N,OPA1
608036,3:193337156:C>T,NM_130837.2:c.678+431C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,4.555,0.001,1KG_EAS_AF,OPA1
608037,3:193337192:A>G,NM_130837.2:c.678+467A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,0.206,0.0014,1KG_AMR_AF,OPA1
608038,3:193337233:T>TC,NM_130837.2:c.678+511dup,\N,\N,6/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
608039,3:193337234:C>T,NM_130837.2:c.678+509C>T,\N,\N,6/30,Benign,\N,intron_variant,5.647,0.0173,1KG_AMR_AF,OPA1
608040,3:193337242:T>C,NM_130837.2:c.678+517T>C,\N,\N,6/30,Unknown significance,\N,intron_variant,0.572,\N,\N,OPA1
608041,3:193337269:G>T,NM_130837.2:c.678+544G>T,\N,\N,6/30,Unknown significance,\N,intron_variant,2.758,0.001,1KG_EAS_AF,OPA1
608042,3:193337306:A>G,NM_130837.2:c.678+581A>G,\N,\N,6/30,Benign,\N,intron_variant,11.02,0.0367,1KG_EAS_AF,OPA1
608043,3:193337336:T>C,NM_130837.2:c.678+611T>C,\N,\N,6/30,Unknown significance,\N,intron_variant,7.174,0.0014,1KG_AMR_AF,OPA1
608044,3:193337357:CTTTG>C,NM_130837.2:c.678+638_678+641del,\N,\N,6/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
608045,3:193337375:TACTC>T,NM_130837.2:c.678+652_678+655del,\N,\N,6/30,Benign,\N,intron_variant,7.97,0.0179,1KG_EAS_AF,OPA1
608046,3:193337407:T>C,NM_130837.2:c.678+682T>C,\N,\N,6/30,Unknown significance,\N,intron_variant,12.92,\N,\N,OPA1
608047,3:193337439:A>G,NM_130837.2:c.678+714A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,11.64,0.002,1KG_EUR_AF,OPA1
608048,3:193337447:T>C,NM_130837.2:c.678+722T>C,\N,\N,6/30,Unknown significance,\N,intron_variant,6.188,\N,\N,OPA1
608049,3:193337555:G>A,NM_130837.2:c.678+830G>A,\N,\N,6/30,Benign,\N,intron_variant,6.157,0.031,1KG_AFR_AF,OPA1
608050,3:193337618:A>G,NM_130837.2:c.678+893A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,6.655,\N,\N,OPA1
608051,3:193337640:C>T,NM_130837.2:c.678+915C>T,\N,\N,6/30,Benign,\N,intron_variant,13.76,0.0179,1KG_EAS_AF,OPA1
608052,3:193337644:TCTTTC>T,NM_130837.2:c.678+923_678+927del,\N,\N,6/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
608053,3:193337653:G>C,NM_130837.2:c.678+928G>C,\N,\N,6/30,Unknown significance,\N,intron_variant,14.85,0.004,1KG_EAS_AF,OPA1
608054,3:193337669:C>T,NM_130837.2:c.678+944C>T,\N,\N,6/30,Benign,\N,intron_variant,15.83,0.0179,1KG_EAS_AF,OPA1
608055,3:193337674:T>C,NM_130837.2:c.678+949T>C,\N,\N,6/30,Unknown significance,\N,intron_variant,1.856,0.001,1KG_EAS_AF,OPA1
608056,3:193337704:G>T,NM_130837.2:c.678+979G>T,\N,\N,6/30,Unknown significance,\N,intron_variant,0.071,\N,\N,OPA1
608057,3:193337710:T>C,NM_130837.2:c.678+985T>C,\N,\N,6/30,Unknown significance,\N,intron_variant,1.808,0.0038,1KG_AFR_AF,OPA1
608058,3:193337741:G>GA,NM_130837.2:c.678+1021dup,\N,\N,6/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
608059,3:193337747:T>C,NM_130837.2:c.678+1022T>C,\N,\N,6/30,Unknown significance,\N,intron_variant,1.133,0.001,1KG_SAS_AF,OPA1
608060,3:193337767:C>T,NM_130837.2:c.678+1042C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,2.518,\N,\N,OPA1
608061,3:193337814:G>A,NM_130837.2:c.678+1089G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,14.44,0.001,1KG_EUR_AF,OPA1
608062,3:193337836:A>G,NM_130837.2:c.678+1111A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,16.45,0.0008,1KG_AFR_AF,OPA1
608063,3:193337860:G>T,NM_130837.2:c.678+1135G>T,\N,\N,6/30,Unknown significance,\N,intron_variant,1.433,0.0008,1KG_AFR_AF,OPA1
608064,3:193337862:GA>G,NM_130837.2:c.678+1146del,\N,\N,6/30,Unknown significance,\N,intron_variant,0.178,\N,\N,OPA1
608065,3:193337871:A>T,NM_130837.2:c.678+1146A>T,\N,\N,6/30,Unknown significance,\N,intron_variant,0.528,0.0008,1KG_AFR_AF,OPA1
608066,3:193337934:A>G,NM_130837.2:c.678+1209A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,4.941,\N,\N,OPA1
608067,3:193337951:G>T,NM_130837.2:c.678+1226G>T,\N,\N,6/30,Unknown significance,\N,intron_variant,2.374,\N,\N,OPA1
608068,3:193337982:C>G,NM_130837.2:c.678+1257C>G,\N,\N,6/30,Benign,\N,intron_variant,11.75,0.0272,1KG_AFR_AF,OPA1
608069,3:193338006:G>T,NM_130837.2:c.678+1281G>T,\N,\N,6/30,Unknown significance,\N,intron_variant,5.48,0.0014,1KG_AMR_AF,OPA1
608070,3:193338076:A>T,NM_130837.2:c.678+1351A>T,\N,\N,6/30,Unknown significance,\N,intron_variant,4.725,0.0014,1KG_AMR_AF,OPA1
608071,3:193338077:T>C,NM_130837.2:c.678+1352T>C,\N,\N,6/30,Unknown significance,\N,intron_variant,7.06,\N,\N,OPA1
608072,3:193338116:G>A,NM_130837.2:c.678+1391G>A,\N,\N,6/30,Benign,\N,intron_variant,3.316,0.0367,1KG_EAS_AF,OPA1
608073,3:193338137:C>T,NM_130837.2:c.678+1412C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,5.348,\N,\N,OPA1
608074,3:193338145:C>G,NM_130837.2:c.678+1420C>G,\N,\N,6/30,Unknown significance,\N,intron_variant,2.239,0.0008,1KG_AFR_AF,OPA1
608075,3:193338147:G>A,NM_130837.2:c.678+1422G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,4.452,0.002,1KG_SAS_AF,OPA1
608076,3:193338150:T>C,NM_130837.2:c.678+1425T>C,\N,\N,6/30,Unknown significance,\N,intron_variant,3.408,\N,\N,OPA1
608077,3:193338165:A>G,NM_130837.2:c.678+1440A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,6.521,0.0008,1KG_AFR_AF,OPA1
608078,3:193338195:T>C,NM_130837.2:c.678+1470T>C,\N,\N,6/30,Unknown significance,\N,intron_variant,9.052,\N,\N,OPA1
608079,3:193338204:A>G,NM_130837.2:c.678+1479A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,9.488,\N,\N,OPA1
608080,3:193338208:A>G,NM_130837.2:c.678+1483A>G,\N,\N,6/30,Benign,\N,intron_variant,8.904,0.0068,1KG_AFR_AF,OPA1
608081,3:193338213:A>G,NM_130837.2:c.678+1488A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,5.682,0.001,1KG_EUR_AF,OPA1
608082,3:193338222:G>A,NM_130837.2:c.678+1497G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,3.131,\N,\N,OPA1
608083,3:193338267:G>A,NM_130837.2:c.678+1542G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,1.502,0.0031,1KG_SAS_AF,OPA1
608084,3:193338335:C>A,NM_130837.2:c.678+1610C>A,\N,\N,6/30,Benign,\N,intron_variant,6.589,0.5832,1KG_AFR_AF,OPA1
608085,3:193338390:T>TC,NM_130837.2:c.678+1669dup,\N,\N,6/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
608086,3:193338391:C>T,NM_130837.2:c.678+1666C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,3.373,\N,\N,OPA1
608087,3:193338394:C>T,NM_130837.2:c.678+1669C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,6.624,0.0008,1KG_AFR_AF,OPA1
608088,3:193338410:A>AT,NM_130837.2:c.678+1695dup,\N,\N,6/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
608089,3:193338410:A>T,NM_130837.2:c.678+1685A>T,\N,\N,6/30,Unknown significance,\N,intron_variant,2.402,\N,\N,OPA1
608090,3:193338411:T>TTA,NM_130837.2:c.678+1687_678+1688insAT,\N,\N,6/30,Benign,\N,intron_variant,\N,0.006,1KG_EAS_AF,OPA1
608091,3:193338412:T>TA,NM_130837.2:c.678+1687_678+1688insA,\N,\N,6/30,Benign,\N,intron_variant,3.544,0.5847,1KG_AFR_AF,OPA1
608092,3:193338413:T>A,NM_130837.2:c.678+1688T>A,\N,\N,6/30,Unknown significance,\N,intron_variant,1.743,\N,\N,OPA1
608093,3:193338413:T>TA,NM_130837.2:c.678+1688_678+1689insA,\N,\N,6/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
608094,3:193338425:A>G,NM_130837.2:c.678+1700A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,5.808,\N,\N,OPA1
608095,3:193338465:C>T,NM_130837.2:c.678+1740C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,12.78,\N,\N,OPA1
608096,3:193338615:G>A,NM_130837.2:c.678+1890G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,5.577,\N,\N,OPA1
608097,3:193338625:G>C,NM_130837.2:c.678+1900G>C,\N,\N,6/30,Unknown significance,\N,intron_variant,0.599,\N,\N,OPA1
608098,3:193338627:T>C,NM_130837.2:c.678+1902T>C,\N,\N,6/30,Unknown significance,\N,intron_variant,2.986,0.004,1KG_EAS_AF,OPA1
608099,3:193338705:C>T,NM_130837.2:c.678+1980C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,15.16,\N,\N,OPA1
608100,3:193338711:T>G,NM_130837.2:c.678+1986T>G,\N,\N,6/30,Unknown significance,\N,intron_variant,14.73,0.0015,1KG_AFR_AF,OPA1
608101,3:193338723:T>G,NM_130837.2:c.678+1998T>G,\N,\N,6/30,Unknown significance,\N,intron_variant,13.9,\N,\N,OPA1
608102,3:193338758:T>C,NM_130837.2:c.678+2033T>C,\N,\N,6/30,Benign,\N,intron_variant,10.63,0.0121,1KG_AFR_AF,OPA1
608103,3:193338821:G>A,NM_130837.2:c.678+2096G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,1.292,0.004,1KG_EAS_AF,OPA1
608104,3:193338845:T>C,NM_130837.2:c.678+2120T>C,\N,\N,6/30,Unknown significance,\N,intron_variant,13.63,0.001,1KG_EUR_AF,OPA1
608105,3:193338847:A>C,NM_130837.2:c.678+2122A>C,\N,\N,6/30,Unknown significance,\N,intron_variant,13.35,0.0008,1KG_AFR_AF,OPA1
608106,3:193338898:G>A,NM_130837.2:c.678+2173G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,6.579,0.0014,1KG_AMR_AF,OPA1
608107,3:193338910:G>A,NM_130837.2:c.678+2185G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,5.875,\N,\N,OPA1
608108,3:193338958:CT>C,NM_130837.2:c.678+2238del,\N,\N,6/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
608109,3:193338965:A>G,NM_130837.2:c.678+2240A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,0.925,0.0015,1KG_AFR_AF,OPA1
608110,3:193338979:A>G,NM_130837.2:c.678+2254A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,4.086,0.0008,1KG_AFR_AF,OPA1
608111,3:193339012:AAAG>A,NM_130837.2:c.678+2289_678+2291del,\N,\N,6/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
608112,3:193339036:A>G,NM_130837.2:c.678+2311A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,7.77,\N,\N,OPA1
608113,3:193339067:A>G,NM_130837.2:c.678+2342A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,5.893,0.001,1KG_EAS_AF,OPA1
608114,3:193339110:G>A,NM_130837.2:c.678+2385G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,6.043,0.0015,1KG_AFR_AF,OPA1
608115,3:193339128:C>A,NM_130837.2:c.678+2403C>A,\N,\N,6/30,Unknown significance,\N,intron_variant,7.585,\N,\N,OPA1
608116,3:193339130:G>C,NM_130837.2:c.678+2405G>C,\N,\N,6/30,Unknown significance,\N,intron_variant,0.534,\N,\N,OPA1
608117,3:193339161:A>G,NM_130837.2:c.678+2436A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,1.257,\N,\N,OPA1
608118,3:193339171:G>A,NM_130837.2:c.678+2446G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,5.377,\N,\N,OPA1
608119,3:193339191:C>T,NM_130837.2:c.678+2466C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,13.37,0.0031,1KG_SAS_AF,OPA1
608120,3:193339243:TC>T,NM_130837.2:c.678+2519del,\N,\N,6/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
608121,3:193339274:C>G,NM_130837.2:c.678+2549C>G,\N,\N,6/30,Unknown significance,\N,intron_variant,5.013,\N,\N,OPA1
608122,3:193339295:G>A,NM_130837.2:c.678+2570G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,2.353,0.0008,1KG_AFR_AF,OPA1
608123,3:193339351:A>G,NM_130837.2:c.678+2626A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,2.873,\N,\N,OPA1
608124,3:193339352:C>G,NM_130837.2:c.678+2627C>G,\N,\N,6/30,Unknown significance,\N,intron_variant,4.632,0.0008,1KG_AFR_AF,OPA1
608125,3:193339366:A>G,NM_130837.2:c.678+2641A>G,\N,\N,6/30,Benign,\N,intron_variant,4.924,0.1051,1KG_AFR_AF,OPA1
608126,3:193339377:A>T,NM_130837.2:c.678+2652A>T,\N,\N,6/30,Unknown significance,\N,intron_variant,3.012,0.0045,1KG_AFR_AF,OPA1
608127,3:193339489:C>T,NM_130837.2:c.678+2764C>T,\N,\N,6/30,Benign,\N,intron_variant,10.43,0.008,1KG_EUR_AF,OPA1
608128,3:193339493:T>C,NM_130837.2:c.678+2768T>C,\N,\N,6/30,Unknown significance,\N,intron_variant,9.64,\N,\N,OPA1
608129,3:193339525:A>G,NM_130837.2:c.678+2800A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,7.466,\N,\N,OPA1
608130,3:193339601:A>G,NM_130837.2:c.678+2876A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,11.64,0.004,1KG_EAS_AF,OPA1
608131,3:193339621:C>T,NM_130837.2:c.678+2896C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,3.776,\N,\N,OPA1
608132,3:193339702:C>T,NM_130837.2:c.678+2977C>T,\N,\N,6/30,Benign,\N,intron_variant,1.534,0.1051,1KG_AFR_AF,OPA1
608133,3:193339738:AT>A,NM_130837.2:c.678+3015del,\N,\N,6/30,Benign,\N,intron_variant,14.62,0.0072,1KG_SAS_AF,OPA1
608134,3:193339765:A>T,NM_130837.2:c.678+3040A>T,\N,\N,6/30,Unknown significance,\N,intron_variant,16.64,0.001,1KG_SAS_AF,OPA1
608135,3:193339810:C>G,NM_130837.2:c.678+3085C>G,\N,\N,6/30,Unknown significance,\N,intron_variant,15.04,\N,\N,OPA1
608136,3:193339902:T>C,NM_130837.2:c.678+3177T>C,\N,\N,6/30,Unknown significance,\N,intron_variant,14.46,0.001,1KG_EUR_AF,OPA1
608137,3:193339913:CT>C,NM_130837.2:c.678+3193del,\N,\N,6/30,Benign,\N,intron_variant,10.45,0.0179,1KG_EAS_AF,OPA1
608138,3:193339933:T>A,NM_130837.2:c.678+3208T>A,\N,\N,6/30,Unknown significance,\N,intron_variant,6.632,\N,\N,OPA1
608139,3:193339935:A>G,NM_130837.2:c.678+3210A>G,\N,\N,6/30,Benign,\N,intron_variant,3.16,0.0227,1KG_AFR_AF,OPA1
608140,3:193340015:C>CTT,NM_130837.2:c.678+3310_678+3311dup,\N,\N,6/30,Unknown significance,\N,intron_variant,6.169,\N,\N,OPA1
608141,3:193340033:T>G,NM_130837.2:c.678+3308T>G,\N,\N,6/30,Unknown significance,\N,intron_variant,1.865,\N,\N,OPA1
608142,3:193340042:G>A,NM_130837.2:c.678+3317G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,0.227,\N,\N,OPA1
608143,3:193340053:C>G,NM_130837.2:c.678+3328C>G,\N,\N,6/30,Unknown significance,\N,intron_variant,1.012,0.001,1KG_EUR_AF,OPA1
608144,3:193340086:T>G,NM_130837.2:c.678+3361T>G,\N,\N,6/30,Unknown significance,\N,intron_variant,2.889,\N,\N,OPA1
608145,3:193340100:C>T,NM_130837.2:c.678+3375C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,1.934,\N,\N,OPA1
608146,3:193340111:G>A,NM_130837.2:c.678+3386G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,0.163,0.001,1KG_EUR_AF,OPA1
608147,3:193340174:C>T,NM_130837.2:c.678+3449C>T,\N,\N,6/30,Benign,\N,intron_variant,0.315,0.0595,1KG_EAS_AF,OPA1
608148,3:193340191:T>G,NM_130837.2:c.678+3466T>G,\N,\N,6/30,Unknown significance,\N,intron_variant,1.878,\N,\N,OPA1
608149,3:193340225:C>T,NM_130837.2:c.678+3500C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,9.161,\N,\N,OPA1
608150,3:193340234:T>A,NM_130837.2:c.678+3509T>A,\N,\N,6/30,Unknown significance,\N,intron_variant,9.722,\N,\N,OPA1
608151,3:193340243:C>G,NM_130837.2:c.678+3518C>G,\N,\N,6/30,Unknown significance,\N,intron_variant,6.969,0.003,1KG_AFR_AF,OPA1
608152,3:193340256:T>G,NM_130837.2:c.678+3531T>G,\N,\N,6/30,Unknown significance,\N,intron_variant,2.951,\N,\N,OPA1
608153,3:193340258:C>T,NM_130837.2:c.678+3533C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,2.448,\N,\N,OPA1
608154,3:193340259:G>A,NM_130837.2:c.678+3534G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,0.022,0.0008,1KG_AFR_AF,OPA1
608155,3:193340261:C>G,NM_130837.2:c.678+3536C>G,\N,\N,6/30,Unknown significance,\N,intron_variant,1.331,\N,\N,OPA1
608156,3:193340265:C>T,NM_130837.2:c.678+3540C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,0.257,0.0008,1KG_AFR_AF,OPA1
608157,3:193340303:A>C,NM_130837.2:c.678+3578A>C,\N,\N,6/30,Unknown significance,\N,intron_variant,0.168,\N,\N,OPA1
608158,3:193340305:C>G,NM_130837.2:c.679-3576C>G,\N,\N,6/30,Unknown significance,\N,intron_variant,1.592,\N,\N,OPA1
608159,3:193340308:G>A,NM_130837.2:c.679-3573G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,1.479,\N,\N,OPA1
608160,3:193340310:A>C,NM_130837.2:c.679-3571A>C,\N,\N,6/30,Benign,\N,intron_variant,0.385,0.5847,1KG_AFR_AF,OPA1
608161,3:193340311:G>A,NM_130837.2:c.679-3570G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,0.129,0.0008,1KG_AFR_AF,OPA1
608162,3:193340343:C>T,NM_130837.2:c.679-3538C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,7.625,0.001,1KG_EAS_AF,OPA1
608163,3:193340346:C>T,NM_130837.2:c.679-3535C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,5.097,0.0038,1KG_AFR_AF,OPA1
608164,3:193340397:A>G,NM_130837.2:c.679-3484A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,4.709,\N,\N,OPA1
608165,3:193340452:C>T,NM_130837.2:c.679-3429C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,1.847,0.0014,1KG_AMR_AF,OPA1
608166,3:193340461:T>G,NM_130837.2:c.679-3420T>G,\N,\N,6/30,Unknown significance,\N,intron_variant,4.358,0.001,1KG_EAS_AF,OPA1
608167,3:193340478:T>A,NM_130837.2:c.679-3403T>A,\N,\N,6/30,Benign,\N,intron_variant,2.506,0.005,1KG_EAS_AF,OPA1
608168,3:193340493:A>G,NM_130837.2:c.679-3388A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,2.484,0.001,1KG_EUR_AF,OPA1
608169,3:193340495:A>G,NM_130837.2:c.679-3386A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,1.319,\N,\N,OPA1
608170,3:193340510:C>T,NM_130837.2:c.679-3371C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,1.382,0.0008,1KG_AFR_AF,OPA1
608171,3:193340530:A>G,NM_130837.2:c.679-3351A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,4.28,\N,\N,OPA1
608172,3:193340535:A>G,NM_130837.2:c.679-3346A>G,\N,\N,6/30,Benign,\N,intron_variant,0.383,0.0367,1KG_EAS_AF,OPA1
608173,3:193340537:C>T,NM_130837.2:c.679-3344C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,1.524,\N,\N,OPA1
608174,3:193340538:G>A,NM_130837.2:c.679-3343G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,3.897,0.001,1KG_EUR_AF,OPA1
608175,3:193340539:G>T,NM_130837.2:c.679-3342G>T,\N,\N,6/30,Benign,\N,intron_variant,1.197,0.122,1KG_EAS_AF,OPA1
608176,3:193340578:G>A,NM_130837.2:c.679-3303G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,1.39,\N,\N,OPA1
608177,3:193340578:G>C,NM_130837.2:c.679-3303G>C,\N,\N,6/30,Unknown significance,\N,intron_variant,0.255,\N,\N,OPA1
608178,3:193340581:A>T,NM_130837.2:c.679-3300A>T,\N,\N,6/30,Unknown significance,\N,intron_variant,2.175,0.0008,1KG_AFR_AF,OPA1
608179,3:193340585:T>G,NM_130837.2:c.679-3296T>G,\N,\N,6/30,Unknown significance,\N,intron_variant,3.853,0.001,1KG_SAS_AF,OPA1
608180,3:193340621:G>T,NM_130837.2:c.679-3260G>T,\N,\N,6/30,Unknown significance,\N,intron_variant,0.893,\N,\N,OPA1
608181,3:193340653:C>A,NM_130837.2:c.679-3228C>A,\N,\N,6/30,Benign,\N,intron_variant,5.466,0.006,1KG_EAS_AF,OPA1
608182,3:193340667:C>G,NM_130837.2:c.679-3214C>G,\N,\N,6/30,Unknown significance,\N,intron_variant,3.992,0.001,1KG_SAS_AF,OPA1
608183,3:193340669:A>G,NM_130837.2:c.679-3212A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,2.7,\N,\N,OPA1
608184,3:193340676:G>A,NM_130837.2:c.679-3205G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,3.726,\N,\N,OPA1
608185,3:193340697:T>G,NM_130837.2:c.679-3184T>G,\N,\N,6/30,Benign,\N,intron_variant,2.989,0.0179,1KG_EAS_AF,OPA1
608186,3:193340709:A>G,NM_130837.2:c.679-3172A>G,\N,\N,6/30,Benign,\N,intron_variant,0.718,0.0367,1KG_EAS_AF,OPA1
608187,3:193340716:C>T,NM_130837.2:c.679-3165C>T,\N,\N,6/30,Benign,\N,intron_variant,5.124,0.0051,1KG_SAS_AF,OPA1
608188,3:193340745:G>T,NM_130837.2:c.679-3136G>T,\N,\N,6/30,Unknown significance,\N,intron_variant,1.792,\N,\N,OPA1
608189,3:193340747:G>A,NM_130837.2:c.679-3134G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,6.554,0.001,1KG_EAS_AF,OPA1
608190,3:193340750:C>T,NM_130837.2:c.679-3131C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,7.368,0.001,1KG_SAS_AF,OPA1
608191,3:193340817:G>T,NM_130837.2:c.679-3064G>T,\N,\N,6/30,Unknown significance,\N,intron_variant,0.845,0.0008,1KG_AFR_AF,OPA1
608192,3:193340844:A>G,NM_130837.2:c.679-3037A>G,\N,\N,6/30,Benign,\N,intron_variant,5.889,0.0082,1KG_SAS_AF,OPA1
608193,3:193340857:G>A,NM_130837.2:c.679-3024G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,3.408,\N,\N,OPA1
608194,3:193340858:T>C,NM_130837.2:c.679-3023T>C,\N,\N,6/30,Unknown significance,\N,intron_variant,1.407,0.001,1KG_EAS_AF,OPA1
608195,3:193340893:C>T,NM_130837.2:c.679-2988C>T,\N,\N,6/30,Benign,\N,intron_variant,0.161,0.005,1KG_EAS_AF,OPA1
608196,3:193340893:CG>C,NM_130837.2:c.679-2987del,\N,\N,6/30,Benign,\N,intron_variant,1.775,0.1051,1KG_AFR_AF,OPA1
608197,3:193340894:G>A,NM_130837.2:c.679-2987G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,1.336,0.002,1KG_EAS_AF,OPA1
608198,3:193340936:C>G,NM_130837.2:c.679-2945C>G,\N,\N,6/30,Unknown significance,\N,intron_variant,3.438,\N,\N,OPA1
608199,3:193340948:A>G,NM_130837.2:c.679-2933A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,3.633,0.001,1KG_SAS_AF,OPA1
608200,3:193340962:G>A,NM_130837.2:c.679-2919G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,1.853,0.001,1KG_EUR_AF,OPA1
608201,3:193340986:G>T,NM_130837.2:c.679-2895G>T,\N,\N,6/30,Benign,\N,intron_variant,0.235,0.0053,1KG_AFR_AF,OPA1
608202,3:193340991:G>T,NM_130837.2:c.679-2890G>T,\N,\N,6/30,Unknown significance,\N,intron_variant,0.537,0.001,1KG_EAS_AF,OPA1
608203,3:193340995:A>G,NM_130837.2:c.679-2886A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,0.016,0.001,1KG_SAS_AF,OPA1
608204,3:193341016:C>T,NM_130837.2:c.679-2865C>T,\N,\N,6/30,Benign,\N,intron_variant,4.37,0.4284,1KG_EUR_AF,OPA1
608205,3:193341047:A>G,NM_130837.2:c.679-2834A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,3.295,\N,\N,OPA1
608206,3:193341078:A>G,NM_130837.2:c.679-2803A>G,\N,\N,6/30,Benign,\N,intron_variant,0.588,0.0068,1KG_AFR_AF,OPA1
608207,3:193341110:T>C,NM_130837.2:c.679-2771T>C,\N,\N,6/30,Unknown significance,\N,intron_variant,0.774,\N,\N,OPA1
608208,3:193341133:T>C,NM_130837.2:c.679-2748T>C,\N,\N,6/30,Unknown significance,\N,intron_variant,2.617,\N,\N,OPA1
608209,3:193341187:G>T,NM_130837.2:c.679-2694G>T,\N,\N,6/30,Unknown significance,\N,intron_variant,0.579,0.001,1KG_SAS_AF,OPA1
608210,3:193341189:T>G,NM_130837.2:c.679-2692T>G,\N,\N,6/30,Unknown significance,\N,intron_variant,4.528,0.0008,1KG_AFR_AF,OPA1
608211,3:193341239:TA>T,NM_130837.2:c.679-2633del,\N,\N,6/30,Benign,\N,intron_variant,3.195,0.0628,1KG_AFR_AF,OPA1
608212,3:193341256:T>G,NM_130837.2:c.679-2625T>G,\N,\N,6/30,Unknown significance,\N,intron_variant,3.021,0.0008,1KG_AFR_AF,OPA1
608213,3:193341327:A>G,NM_130837.2:c.679-2554A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,0.253,0.001,1KG_EAS_AF,OPA1
608214,3:193341477:G>T,NM_130837.2:c.679-2404G>T,\N,\N,6/30,Unknown significance,\N,intron_variant,0.541,0.0008,1KG_AFR_AF,OPA1
608215,3:193341505:A>C,NM_130837.2:c.679-2376A>C,\N,\N,6/30,Unknown significance,\N,intron_variant,0.669,0.001,1KG_EAS_AF,OPA1
608216,3:193341506:G>A,NM_130837.2:c.679-2375G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,3.622,\N,\N,OPA1
608217,3:193341511:G>C,NM_130837.2:c.679-2370G>C,\N,\N,6/30,Unknown significance,\N,intron_variant,1.022,\N,\N,OPA1
608218,3:193341538:T>C,NM_130837.2:c.679-2343T>C,\N,\N,6/30,Benign,\N,intron_variant,3.957,0.0257,1KG_AFR_AF,OPA1
608219,3:193341574:A>G,NM_130837.2:c.679-2307A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,1.933,\N,\N,OPA1
608220,3:193341576:A>G,NM_130837.2:c.679-2305A>G,\N,\N,6/30,Benign,\N,intron_variant,2.449,0.0051,1KG_SAS_AF,OPA1
608221,3:193341578:A>T,NM_130837.2:c.679-2303A>T,\N,\N,6/30,Benign,\N,intron_variant,3.051,0.0367,1KG_EAS_AF,OPA1
608222,3:193341580:TTCTTCC>T,NM_130837.2:c.679-2293_679-2288del,\N,\N,6/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
608223,3:193341598:C>T,NM_130837.2:c.679-2283C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,6.033,0.0008,1KG_AFR_AF,OPA1
608224,3:193341645:G>A,NM_130837.2:c.679-2236G>A,\N,\N,6/30,Benign,\N,intron_variant,6.969,0.0076,1KG_AFR_AF,OPA1
608225,3:193341648:A>G,NM_130837.2:c.679-2233A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,4.185,0.001,1KG_EUR_AF,OPA1
608226,3:193341665:T>G,NM_130837.2:c.679-2216T>G,\N,\N,6/30,Unknown significance,\N,intron_variant,5.843,\N,\N,OPA1
608227,3:193341700:A>G,NM_130837.2:c.679-2181A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,7.903,\N,\N,OPA1
608228,3:193341709:G>C,NM_130837.2:c.679-2172G>C,\N,\N,6/30,Unknown significance,\N,intron_variant,12.54,\N,\N,OPA1
608229,3:193341755:T>A,NM_130837.2:c.679-2126T>A,\N,\N,6/30,Unknown significance,\N,intron_variant,14.43,0.001,1KG_SAS_AF,OPA1
608230,3:193341795:T>G,NM_130837.2:c.679-2086T>G,\N,\N,6/30,Unknown significance,\N,intron_variant,11.64,\N,\N,OPA1
608231,3:193341807:C>A,NM_130837.2:c.679-2074C>A,\N,\N,6/30,Unknown significance,\N,intron_variant,9.973,0.001,1KG_SAS_AF,OPA1
608232,3:193341822:A>G,NM_130837.2:c.679-2059A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,12.08,\N,\N,OPA1
608233,3:193341880:G>A,NM_130837.2:c.679-2001G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,1.476,\N,\N,OPA1
608234,3:193341907:C>T,NM_130837.2:c.679-1974C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,1.226,0.001,1KG_EAS_AF,OPA1
608235,3:193341936:G>T,NM_130837.2:c.679-1945G>T,\N,\N,6/30,Unknown significance,\N,intron_variant,4.502,0.0014,1KG_AMR_AF,OPA1
608236,3:193341946:C>G,NM_130837.2:c.679-1935C>G,\N,\N,6/30,Unknown significance,\N,intron_variant,6.578,\N,\N,OPA1
608237,3:193341957:C>T,NM_130837.2:c.679-1924C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,0.537,\N,\N,OPA1
608238,3:193341971:G>A,NM_130837.2:c.679-1910G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,4.887,\N,\N,OPA1
608239,3:193341974:A>T,NM_130837.2:c.679-1907A>T,\N,\N,6/30,Unknown significance,\N,intron_variant,3.015,\N,\N,OPA1
608240,3:193341975:T>G,NM_130837.2:c.679-1906T>G,\N,\N,6/30,Unknown significance,\N,intron_variant,5.638,\N,\N,OPA1
608241,3:193341976:A>G,NM_130837.2:c.679-1905A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,0.78,0.001,1KG_SAS_AF,OPA1
608242,3:193342074:C>T,NM_130837.2:c.679-1807C>T,\N,\N,6/30,Benign,\N,intron_variant,4.939,0.0257,1KG_AFR_AF,OPA1
608243,3:193342107:A>G,NM_130837.2:c.679-1774A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,4.065,\N,\N,OPA1
608244,3:193342116:C>T,NM_130837.2:c.679-1765C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,6.425,\N,\N,OPA1
608245,3:193342146:A>G,NM_130837.2:c.679-1735A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,2.208,\N,\N,OPA1
608246,3:193342175:C>T,NM_130837.2:c.679-1706C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,6.212,\N,\N,OPA1
608247,3:193342189:A>G,NM_130837.2:c.679-1692A>G,\N,\N,6/30,Benign,\N,intron_variant,6.336,0.0272,1KG_AFR_AF,OPA1
608248,3:193342197:C>A,NM_130837.2:c.679-1684C>A,\N,\N,6/30,Unknown significance,\N,intron_variant,11.1,\N,\N,OPA1
608249,3:193342238:A>G,NM_130837.2:c.679-1643A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,3.475,0.001,1KG_EUR_AF,OPA1
608250,3:193342297:C>T,NM_130837.2:c.679-1584C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,1.013,\N,\N,OPA1
608251,3:193342298:T>C,NM_130837.2:c.679-1583T>C,\N,\N,6/30,Unknown significance,\N,intron_variant,2.261,0.0015,1KG_AFR_AF,OPA1
608252,3:193342316:G>A,NM_130837.2:c.679-1565G>A,\N,\N,6/30,Benign,\N,intron_variant,2.007,0.0106,1KG_AFR_AF,OPA1
608253,3:193342336:TA>T,NM_130837.2:c.679-1540del,\N,\N,6/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
608254,3:193342347:A>C,NM_130837.2:c.679-1534A>C,\N,\N,6/30,Unknown significance,\N,intron_variant,0.19,\N,\N,OPA1
608255,3:193342400:A>T,NM_130837.2:c.679-1481A>T,\N,\N,6/30,Unknown significance,\N,intron_variant,1.182,\N,\N,OPA1
608256,3:193342413:T>C,NM_130837.2:c.679-1468T>C,\N,\N,6/30,Unknown significance,\N,intron_variant,4.921,\N,\N,OPA1
608257,3:193342429:T>C,NM_130837.2:c.679-1452T>C,\N,\N,6/30,Unknown significance,\N,intron_variant,2.171,0.0008,1KG_AFR_AF,OPA1
608258,3:193342442:A>G,NM_130837.2:c.679-1439A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,4.23,\N,\N,OPA1
608259,3:193342468:A>G,NM_130837.2:c.679-1413A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,0.874,0.001,1KG_SAS_AF,OPA1
608260,3:193342506:A>G,NM_130837.2:c.679-1375A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,6.608,0.0031,1KG_SAS_AF,OPA1
608261,3:193342536:C>A,NM_130837.2:c.679-1345C>A,\N,\N,6/30,Unknown significance,\N,intron_variant,6.141,\N,\N,OPA1
608262,3:193342555:A>T,NM_130837.2:c.679-1326A>T,\N,\N,6/30,Unknown significance,\N,intron_variant,2.158,\N,\N,OPA1
608263,3:193342565:A>G,NM_130837.2:c.679-1316A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,4.731,0.0023,1KG_AFR_AF,OPA1
608264,3:193342594:CAG>C,NM_130837.2:c.679-1285_679-1284del,\N,\N,6/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
608265,3:193342662:T>A,NM_130837.2:c.679-1219T>A,\N,\N,6/30,Unknown significance,\N,intron_variant,8.783,0.001,1KG_EUR_AF,OPA1
608266,3:193342664:G>A,NM_130837.2:c.679-1217G>A,\N,\N,6/30,Benign,\N,intron_variant,6.087,0.0143,1KG_SAS_AF,OPA1
608267,3:193342664:G>T,NM_130837.2:c.679-1217G>T,\N,\N,6/30,Unknown significance,\N,intron_variant,4.145,0.0023,1KG_AFR_AF,OPA1
608268,3:193342672:A>AT,NM_130837.2:c.679-1203dup,\N,\N,6/30,Benign,\N,intron_variant,0.301,0.0628,1KG_AFR_AF,OPA1
608269,3:193342673:T>G,NM_130837.2:c.679-1208T>G,\N,\N,6/30,Unknown significance,\N,intron_variant,2.618,0.001,1KG_SAS_AF,OPA1
608270,3:193342680:A>C,NM_130837.2:c.679-1201A>C,\N,\N,6/30,Unknown significance,\N,intron_variant,0.635,0.003,1KG_AFR_AF,OPA1
608271,3:193342788:C>T,NM_130837.2:c.679-1093C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,4.833,0.0008,1KG_AFR_AF,OPA1
608272,3:193342803:A>C,NM_130837.2:c.679-1078A>C,\N,\N,6/30,Unknown significance,\N,intron_variant,2.893,0.0008,1KG_AFR_AF,OPA1
608273,3:193342810:A>G,NM_130837.2:c.679-1071A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,4.578,\N,\N,OPA1
608274,3:193342818:C>T,NM_130837.2:c.679-1063C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,3.456,0.001,1KG_EUR_AF,OPA1
608275,3:193342869:G>C,NM_130837.2:c.679-1012G>C,\N,\N,6/30,Unknown significance,\N,intron_variant,12.17,\N,\N,OPA1
608276,3:193342869:G>T,NM_130837.2:c.679-1012G>T,\N,\N,6/30,Unknown significance,\N,intron_variant,12.8,0.001,1KG_EAS_AF,OPA1
608277,3:193342880:A>G,NM_130837.2:c.679-1001A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,9.822,0.001,1KG_SAS_AF,OPA1
608278,3:193342884:C>A,NM_130837.2:c.679-997C>A,\N,\N,6/30,Unknown significance,\N,intron_variant,7.984,0.001,1KG_EAS_AF,OPA1
608279,3:193342895:T>G,NM_130837.2:c.679-986T>G,\N,\N,6/30,Unknown significance,\N,intron_variant,6.343,\N,\N,OPA1
608280,3:193342903:C>T,NM_130837.2:c.679-978C>T,\N,\N,6/30,Benign,\N,intron_variant,5.762,0.0367,1KG_EAS_AF,OPA1
608281,3:193342916:C>T,NM_130837.2:c.679-965C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,2.293,\N,\N,OPA1
608282,3:193342946:G>A,NM_130837.2:c.679-935G>A,\N,\N,6/30,Benign,\N,intron_variant,2.904,0.0053,1KG_AFR_AF,OPA1
608283,3:193342949:A>G,NM_130837.2:c.679-932A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,4.245,0.0008,1KG_AFR_AF,OPA1
608284,3:193342961:A>C,NM_130837.2:c.679-920A>C,\N,\N,6/30,Unknown significance,\N,intron_variant,5.86,0.002,1KG_SAS_AF,OPA1
608285,3:193342975:G>A,NM_130837.2:c.679-906G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,5.742,0.0014,1KG_AMR_AF,OPA1
608286,3:193343000:A>G,NM_130837.2:c.679-881A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,0.621,0.001,1KG_SAS_AF,OPA1
608287,3:193343009:C>G,NM_130837.2:c.679-872C>G,\N,\N,6/30,Benign,\N,intron_variant,1.288,0.0068,1KG_AFR_AF,OPA1
608288,3:193343066:G>A,NM_130837.2:c.679-815G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,2.398,\N,\N,OPA1
608289,3:193343070:A>T,NM_130837.2:c.679-811A>T,\N,\N,6/30,Unknown significance,\N,intron_variant,2.463,0.001,1KG_EAS_AF,OPA1
608290,3:193343072:G>A,NM_130837.2:c.679-809G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,5.414,\N,\N,OPA1
608291,3:193343074:C>A,NM_130837.2:c.679-807C>A,\N,\N,6/30,Unknown significance,\N,intron_variant,8.378,\N,\N,OPA1
608292,3:193343076:A>G,NM_130837.2:c.679-805A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,8.599,0.003,1KG_EUR_AF,OPA1
608293,3:193343079:CTG>C,NM_130837.2:c.679-798_679-797del,\N,\N,6/30,Benign,\N,intron_variant,4.64,0.0469,1KG_AFR_AF,OPA1
608294,3:193343146:T>C,NM_130837.2:c.679-735T>C,\N,\N,6/30,Unknown significance,\N,intron_variant,9.795,\N,\N,OPA1
608295,3:193343151:G>A,NM_130837.2:c.679-730G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,11.63,\N,\N,OPA1
608296,3:193343183:CTG>C,NM_130837.2:c.679-696_679-695del,\N,\N,6/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
608297,3:193343201:T>G,NM_130837.2:c.679-680T>G,\N,\N,6/30,Unknown significance,\N,intron_variant,11.29,0.002,1KG_EAS_AF,OPA1
608298,3:193343251:G>C,NM_130837.2:c.679-630G>C,\N,\N,6/30,Unknown significance,\N,intron_variant,1.353,0.001,1KG_SAS_AF,OPA1
608299,3:193343271:A>T,NM_130837.2:c.679-610A>T,\N,\N,6/30,Unknown significance,\N,intron_variant,1.135,0.0038,1KG_AFR_AF,OPA1
608300,3:193343282:AAAC>A,NM_130837.2:c.679-595_679-593del,\N,\N,6/30,Benign,\N,intron_variant,4.404,0.1051,1KG_AFR_AF,OPA1
608301,3:193343288:C>T,NM_130837.2:c.679-593C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,4.421,0.0015,1KG_AFR_AF,OPA1
608302,3:193343333:A>T,NM_130837.2:c.679-548A>T,\N,\N,6/30,Benign,\N,intron_variant,0.5,0.0113,1KG_AFR_AF,OPA1
608303,3:193343337:A>C,NM_130837.2:c.679-544A>C,\N,\N,6/30,Unknown significance,\N,intron_variant,0.706,0.001,1KG_EUR_AF,OPA1
608304,3:193343353:C>T,NM_130837.2:c.679-528C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,6.302,0.0015,1KG_AFR_AF,OPA1
608305,3:193343367:C>T,NM_130837.2:c.679-514C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,12.17,0.002,1KG_EAS_AF,OPA1
608306,3:193343373:G>A,NM_130837.2:c.679-508G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,19.33,\N,\N,OPA1
608307,3:193343446:A>G,NM_130837.2:c.679-435A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,4.095,0.0045,1KG_AFR_AF,OPA1
608308,3:193343479:G>A,NM_130837.2:c.679-402G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,0.598,0.0014,1KG_AMR_AF,OPA1
608309,3:193343490:A>G,NM_130837.2:c.679-391A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,1.444,\N,\N,OPA1
608310,3:193343503:A>G,NM_130837.2:c.679-378A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,0.723,0.0014,1KG_AMR_AF,OPA1
608311,3:193343508:TC>T,NM_130837.2:c.679-371del,\N,\N,6/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
608312,3:193343511:T>G,NM_130837.2:c.679-370T>G,\N,\N,6/30,Unknown significance,\N,intron_variant,4.06,\N,\N,OPA1
608313,3:193343527:G>A,NM_130837.2:c.679-354G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,3.377,\N,\N,OPA1
608314,3:193343534:A>G,NM_130837.2:c.679-347A>G,\N,\N,6/30,Benign,\N,intron_variant,0.541,0.0098,1KG_AFR_AF,OPA1
608315,3:193343541:T>A,NM_130837.2:c.679-340T>A,\N,\N,6/30,Unknown significance,\N,intron_variant,7.275,0.001,1KG_SAS_AF,OPA1
608316,3:193343542:T>C,NM_130837.2:c.679-339T>C,\N,\N,6/30,Unknown significance,\N,intron_variant,3.44,\N,\N,OPA1
608317,3:193343554:A>G,NM_130837.2:c.679-327A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,1.471,0.0029,1KG_AMR_AF,OPA1
608318,3:193343565:T>TA,NM_130837.2:c.679-301dup,\N,\N,6/30,Unknown significance,\N,intron_variant,0.324,\N,\N,OPA1
608319,3:193343579:A>T,NM_130837.2:c.679-302A>T,\N,\N,6/30,Unknown significance,\N,intron_variant,0.554,\N,\N,OPA1
608320,3:193343721:C>T,NM_130837.2:c.679-160C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,14.39,0.001,1KG_EUR_AF,OPA1
608321,3:193343722:G>A,NM_130837.2:c.679-159G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,13.76,0.001,1KG_EUR_AF,OPA1
608322,3:193343744:C>T,NM_130837.2:c.679-137C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,3.484,\N,\N,OPA1
608323,3:193343760:T>G,NM_130837.2:c.679-121T>G,\N,\N,6/30,Unknown significance,\N,intron_variant,18.57,0.001,1KG_EAS_AF,OPA1
608324,3:193343761:C>G,NM_130837.2:c.679-120C>G,\N,\N,6/30,Benign,\N,intron_variant,18.28,0.4274,1KG_EUR_AF,OPA1
608325,3:193343781:C>T,NM_130837.2:c.679-100C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,6.723,0.0029,1KG_AMR_AF,OPA1
608326,3:193343783:A>G,NM_130837.2:c.679-98A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,5.21,0.0008,1KG_AFR_AF,OPA1
608327,3:193343791:C>G,NM_130837.2:c.679-90C>G,\N,\N,6/30,Unknown significance,\N,intron_variant,8.02,\N,\N,OPA1
608328,3:193343824:G>A,NM_130837.2:c.679-57G>A,\N,\N,6/30,Unknown significance,\N,intron_variant,16.82,\N,\N,OPA1
608329,3:193343837:C>T,NM_130837.2:c.679-44C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,19.32,\N,\N,OPA1
608330,3:193343847:A>G,NM_130837.2:c.679-34A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,17.92,0.000346901,EXAC_EAS_AF,OPA1
608331,3:193343854:C>T,NM_130837.2:c.679-27C>T,\N,\N,6/30,Unknown significance,\N,intron_variant,20.5,0.0000605914,EXAC_SAS_AF,OPA1
608332,3:193343863:A>G,NM_130837.2:c.679-18A>G,\N,\N,6/30,Unknown significance,\N,intron_variant,19.36,0.0000961908,EXAC_AFR_AF,OPA1
608333,3:193343873:C>T,NM_130837.2:c.679-8C>T,\N,\N,6/30,Benign,\N,splice_region_variant&intron_variant,18.35,0.0183725,EXAC_AFR_AF,OPA1
608334,3:193343874:G>A,NM_130837.2:c.679-7G>A,\N,\N,6/30,Unknown significance,\N,splice_region_variant&intron_variant,13,0.000453926,EVS_AA_AF,OPA1
608335,3:193343874:G>C,NM_130837.2:c.679-7G>C,\N,\N,6/30,Unknown significance,\N,splice_region_variant&intron_variant,11.97,0.0000149876,EXAC_NFE_AF,OPA1
608336,3:193343877:G>A,NM_130837.2:c.679-4G>A,\N,\N,6/30,Unknown significance,\N,splice_region_variant&intron_variant,16.99,0.000060562,EXAC_SAS_AF,OPA1
608337,3:193343879:A>G,NM_130837.2:c.679-2A>G,\N,\N,6/30,Unknown significance,\N,splice_acceptor_variant,25.3,0.0000961354,EXAC_AFR_AF,OPA1
608338,3:193343880:G>C,NM_130837.2:c.679-1G>C,\N,\N,6/30,Unknown significance,\N,splice_acceptor_variant,25.6,0.000181686,EXAC_SAS_AF,OPA1
608339,3:193343887:C>A,NM_130837.2:c.685C>A,NP_570850.2:p.Leu229Ile,7/31,\N,Unknown significance,\N,missense_variant,23.1,0.0000149867,EXAC_NFE_AF,OPA1
608340,3:193343898:C>T,NM_130837.2:c.696C>T,NP_570850.2:p.Leu232=,7/31,\N,Unknown significance,\N,synonymous_variant,14.07,0.000116279,EVS_EA_AF,OPA1
608341,3:193343904:C>G,NM_130837.2:c.702C>G,NP_570850.2:p.Leu234=,7/31,\N,Unknown significance,\N,synonymous_variant,13.47,0.000060562,EXAC_SAS_AF,OPA1
608342,3:193343906:TACA>T,NM_130837.2:c.712_714del,NP_570850.2:p.Gln238del,7/31,\N,Likely pathogenic,Glaucoma,inframe_deletion,23,0.000462321,EXAC_EAS_AF,OPA1
608343,3:193343906:T>C,NM_130837.2:c.704T>C,NP_570850.2:p.Leu235Ser,7/31,\N,Unknown significance,\N,missense_variant,18.82,0.000346741,EXAC_EAS_AF,OPA1
608344,3:193343908:C>A,NM_130837.2:c.706C>A,NP_570850.2:p.Gln236Lys,7/31,\N,Likely benign,\N,missense_variant,17.46,0.000121124,EXAC_SAS_AF,OPA1
608345,3:193343920:C>G,NM_130837.2:c.718C>G,NP_570850.2:p.Gln240Glu,7/31,\N,Unknown significance,\N,missense_variant,7.245,0.000115554,EXAC_EAS_AF,OPA1
608346,3:193343921:A>G,NM_130837.2:c.719A>G,NP_570850.2:p.Gln240Arg,7/31,\N,Unknown significance,\N,missense_variant,15.68,0.001,1KG_SAS_AF,OPA1
608347,3:193343924:A>G,NM_130837.2:c.722A>G,NP_570850.2:p.Glu241Gly,7/31,\N,Unknown significance,\N,missense_variant,19.66,0.000226963,EVS_AA_AF,OPA1
608348,3:193343925:G>A,NM_130837.2:c.723G>A,NP_570850.2:p.Glu241=,7/31,\N,Unknown significance,\N,synonymous_variant,11.47,0.0000149867,EXAC_NFE_AF,OPA1
608349,3:193343926:C>T,NM_130837.2:c.724C>T,NP_570850.2:p.His242Tyr,7/31,\N,Likely benign,\N,missense_variant,20.9,0.0000149876,EXAC_NFE_AF,OPA1
608350,3:193343927:A>C,NM_130837.2:c.725A>C,NP_570850.2:p.His242Pro,7/31,\N,Likely benign,\N,missense_variant,15.71,0.00011558,EXAC_EAS_AF,OPA1
608351,3:193343927:A>G,NM_130837.2:c.725A>G,NP_570850.2:p.His242Arg,7/31,\N,Likely benign,\N,missense_variant,10.7,0.0000149871,EXAC_NFE_AF,OPA1
608352,3:193343939:C>T,NM_130837.2:c.737C>T,NP_570850.2:p.Ala246Val,7/31,\N,Likely benign,\N,missense_variant,22.8,0.000346821,EXAC_EAS_AF,OPA1
608353,3:193343940:G>A,NM_130837.2:c.738G>A,NP_570850.2:p.Ala246=,7/31,\N,Unknown significance,\N,synonymous_variant,12.75,\N,\N,OPA1
608354,3:193343941:C>T,NM_130836.2:c.685C>T,NP_570849.2:p.Arg229Cys,6/30,\N,Unknown significance,\N,missense_variant,27.4,0.000226963,EVS_AA_AF,OPA1
608355,3:193343942:G>A,NM_130836.2:c.686G>A,NP_570849.2:p.Arg229His,6/30,\N,Pathogenic,Optic neuropathy,missense_variant,23.2,0.000121139,EXAC_SAS_AF,OPA1
608356,3:193343942:G>T,NM_130837.2:c.740G>T,NP_570850.2:p.Arg247Leu,7/31,\N,Unknown significance,\N,missense_variant,22.9,0.00110132,EXAC_OTH_AF,OPA1
608357,3:193343949:C>T,NM_130837.2:c.747C>T,NP_570850.2:p.Ala249=,7/31,\N,Unknown significance,\N,synonymous_variant,19.22,0.000121139,EXAC_SAS_AF,OPA1
608358,3:193343950:G>A,NM_130837.2:c.748G>A,NP_570850.2:p.Ala250Thr,7/31,\N,Benign,\N,missense_variant,15.91,0.0068,1KG_AFR_AF,OPA1
608359,3:193343958:A>G,NM_130837.2:c.756A>G,NP_570850.2:p.Gln252=,7/31,\N,Unknown significance,\N,synonymous_variant,7.417,0.000226963,EVS_AA_AF,OPA1
608360,3:193343961:T>C,NM_130837.2:c.759T>C,NP_570850.2:p.Tyr253=,7/31,\N,Unknown significance,\N,synonymous_variant,1.662,0.0000605694,EXAC_SAS_AF,OPA1
608361,3:193343966:C>T,NM_130836.2:c.710C>T,NP_570849.2:p.Thr237Met,6/30,\N,Unknown significance,\N,missense_variant,22.7,0.0000149912,EXAC_NFE_AF,OPA1
608362,3:193343967:G>A,NM_130837.2:c.765G>A,NP_570850.2:p.Thr255=,7/31,\N,Unknown significance,\N,synonymous_variant,13.53,0.000692401,EXAC_AMR_AF,OPA1
608363,3:193343970:C>G,NM_130837.2:c.768C>G,NP_570850.2:p.Ser256Arg,7/31,\N,Pathogenic,Optic atrophy| ataxia & spasticity,missense_variant,18.66,0.0000149943,EXAC_NFE_AF,OPA1
608364,3:193343972:A>C,NM_130837.2:c.770A>C,NP_570850.2:p.Tyr257Ser,7/31,\N,Unknown significance,\N,missense_variant,15.82,0.0000149943,EXAC_NFE_AF,OPA1
608365,3:193343986:C>T,NM_130837.2:c.784C>T,NP_570850.2:p.Arg262Cys,7/31,\N,Unknown significance,\N,missense_variant,34,0.0000150177,EXAC_NFE_AF,OPA1
608366,3:193343987:G>A,NM_130837.2:c.785G>A,NP_570850.2:p.Arg262His,7/31,\N,Unknown significance,\N,missense_variant,25.3,0.0000150281,EXAC_NFE_AF,OPA1
608367,3:193343987:G>T,NM_130837.2:c.785G>T,NP_570850.2:p.Arg262Leu,7/31,\N,Unknown significance,\N,missense_variant,24.6,0.0000868206,EXAC_AMR_AF,OPA1
608368,3:193343991:G>A,NM_130837.2:c.789G>A,NP_570850.2:p.Lys263=,7/31,\N,Unknown significance,\N,splice_region_variant&synonymous_variant,18.54,\N,\N,OPA1
608369,3:193343996:TG>T,NM_130837.2:c.789+7del,\N,\N,7/30,Unknown significance,\N,splice_region_variant&intron_variant,17.2,0.000087184,EXAC_AMR_AF,OPA1
608370,3:193343999:A>G,NM_130837.2:c.789+8A>G,\N,\N,7/30,Unknown significance,\N,splice_region_variant&intron_variant,13.2,0.0000151021,EXAC_NFE_AF,OPA1
608371,3:193344001:G>A,NM_130837.2:c.789+10G>A,\N,\N,7/30,Unknown significance,\N,intron_variant,20.8,\N,\N,OPA1
608372,3:193344002:G>T,NM_130837.2:c.789+11G>T,\N,\N,7/30,Unknown significance,\N,intron_variant,18.54,0.001,1KG_SAS_AF,OPA1
608373,3:193344006:A>G,NM_130837.2:c.789+15A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,18.83,0.000176149,EXAC_AMR_AF,OPA1
608374,3:193344012:G>C,NM_130837.2:c.789+21G>C,\N,\N,7/30,Unknown significance,\N,intron_variant,16.18,\N,\N,OPA1
608375,3:193344012:G>GC,NM_130837.2:c.789+22dup,\N,\N,7/30,Unknown significance,\N,intron_variant,17.35,\N,\N,OPA1
608376,3:193344017:C>T,NM_130837.2:c.789+26C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,6.579,0.000119503,EXAC_EAS_AF,OPA1
608377,3:193344018:G>A,NM_130837.2:c.789+27G>A,\N,\N,7/30,Unknown significance,\N,intron_variant,3.514,0.00053802,EXAC_AMR_AF,OPA1
608378,3:193344018:G>C,NM_130837.2:c.789+27G>C,\N,\N,7/30,Benign,\N,intron_variant,1.21,0.0099,1KG_EAS_AF,OPA1
608379,3:193344019:A>G,NM_130837.2:c.789+28A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,1.023,0.000119703,EXAC_EAS_AF,OPA1
608380,3:193344022:C>T,NM_130837.2:c.789+31C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,0.392,0.000232558,EVS_EA_AF,OPA1
608381,3:193344024:TTCACAC>T,NM_130837.2:c.789+35_789+40del,\N,\N,7/30,Unknown significance,\N,intron_variant,18.57,0.00043024,EXAC_SAS_AF,OPA1
608382,3:193344028:C>T,NM_130837.2:c.789+37C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,14.65,\N,\N,OPA1
608383,3:193344029:A>G,NM_130837.2:c.789+38A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,12.87,0.0000154431,EXAC_NFE_AF,OPA1
608384,3:193344034:T>C,NM_130837.2:c.789+43T>C,\N,\N,7/30,Unknown significance,\N,intron_variant,19.27,0.0000617818,EXAC_SAS_AF,OPA1
608385,3:193344057:G>A,NM_130837.2:c.789+66G>A,\N,\N,7/30,Unknown significance,\N,intron_variant,15.69,\N,\N,OPA1
608386,3:193344099:T>C,NM_130837.2:c.789+108T>C,\N,\N,7/30,Unknown significance,\N,intron_variant,4.323,\N,\N,OPA1
608387,3:193344123:A>G,NM_130837.2:c.789+132A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,1.951,0.001,1KG_EAS_AF,OPA1
608388,3:193344123:A>T,NM_130837.2:c.789+132A>T,\N,\N,7/30,Unknown significance,\N,intron_variant,0.984,\N,\N,OPA1
608389,3:193344127:A>G,NM_130837.2:c.789+136A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,4.488,0.001,1KG_SAS_AF,OPA1
608390,3:193344141:T>C,NM_130837.2:c.789+150T>C,\N,\N,7/30,Unknown significance,\N,intron_variant,0.056,0.0008,1KG_AFR_AF,OPA1
608391,3:193344155:T>A,NM_130837.2:c.789+164T>A,\N,\N,7/30,Unknown significance,\N,intron_variant,7.216,\N,\N,OPA1
608392,3:193344217:T>C,NM_130837.2:c.789+226T>C,\N,\N,7/30,Unknown significance,\N,intron_variant,6.238,\N,\N,OPA1
608393,3:193344226:C>T,NM_130837.2:c.789+235C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,6.593,0.0029,1KG_AMR_AF,OPA1
608394,3:193344230:A>G,NM_130837.2:c.789+239A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,1.405,0.0008,1KG_AFR_AF,OPA1
608395,3:193344251:A>G,NM_130837.2:c.789+260A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,4.56,0.0014,1KG_AMR_AF,OPA1
608396,3:193344275:T>G,NM_130837.2:c.789+284T>G,\N,\N,7/30,Unknown significance,\N,intron_variant,8.455,\N,\N,OPA1
608397,3:193344287:T>C,NM_130837.2:c.789+296T>C,\N,\N,7/30,Unknown significance,\N,intron_variant,7.603,\N,\N,OPA1
608398,3:193344290:T>C,NM_130837.2:c.789+299T>C,\N,\N,7/30,Unknown significance,\N,intron_variant,7.418,\N,\N,OPA1
608399,3:193344299:C>T,NM_130837.2:c.789+308C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,6.507,0.001,1KG_EUR_AF,OPA1
608400,3:193344300:C>T,NM_130837.2:c.789+309C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,3.611,\N,\N,OPA1
608401,3:193344358:A>T,NM_130837.2:c.789+367A>T,\N,\N,7/30,Unknown significance,\N,intron_variant,2.511,0.002,1KG_EAS_AF,OPA1
608402,3:193344359:A>G,NM_130837.2:c.789+368A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,7.004,0.0029,1KG_AMR_AF,OPA1
608403,3:193344407:T>C,NM_130837.2:c.789+416T>C,\N,\N,7/30,Unknown significance,\N,intron_variant,8.726,\N,\N,OPA1
608404,3:193344433:C>G,NM_130837.2:c.789+442C>G,\N,\N,7/30,Unknown significance,\N,intron_variant,0.165,0.0008,1KG_AFR_AF,OPA1
608405,3:193344442:T>C,NM_130837.2:c.789+451T>C,\N,\N,7/30,Unknown significance,\N,intron_variant,1.123,0.001,1KG_EUR_AF,OPA1
608406,3:193344479:G>A,NM_130837.2:c.789+488G>A,\N,\N,7/30,Unknown significance,\N,intron_variant,5.673,\N,\N,OPA1
608407,3:193344521:C>T,NM_130837.2:c.789+530C>T,\N,\N,7/30,Benign,\N,intron_variant,0.11,0.0086,1KG_AMR_AF,OPA1
608408,3:193344522:G>A,NM_130837.2:c.789+531G>A,\N,\N,7/30,Unknown significance,\N,intron_variant,1.057,0.002,1KG_SAS_AF,OPA1
608409,3:193344555:A>G,NM_130837.2:c.789+564A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,3.717,\N,\N,OPA1
608410,3:193344576:C>T,NM_130837.2:c.789+585C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,5.359,\N,\N,OPA1
608411,3:193344581:G>T,NM_130837.2:c.789+590G>T,\N,\N,7/30,Unknown significance,\N,intron_variant,2.024,0.003,1KG_EAS_AF,OPA1
608412,3:193344591:C>T,NM_130837.2:c.789+600C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,1.881,0.002,1KG_EAS_AF,OPA1
608413,3:193344612:G>A,NM_130837.2:c.789+621G>A,\N,\N,7/30,Unknown significance,\N,intron_variant,3.642,0.0014,1KG_AMR_AF,OPA1
608414,3:193344633:A>G,NM_130837.2:c.789+642A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,13.68,\N,\N,OPA1
608415,3:193344648:G>A,NM_130837.2:c.789+657G>A,\N,\N,7/30,Unknown significance,\N,intron_variant,3.923,\N,\N,OPA1
608416,3:193344657:T>C,NM_130837.2:c.789+666T>C,\N,\N,7/30,Benign,\N,intron_variant,4.153,0.0069,1KG_EAS_AF,OPA1
608417,3:193344675:A>G,NM_130837.2:c.789+684A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,4.486,0.001,1KG_SAS_AF,OPA1
608418,3:193344687:G>A,NM_130837.2:c.789+696G>A,\N,\N,7/30,Benign,\N,intron_variant,0.064,0.0083,1KG_AFR_AF,OPA1
608419,3:193344724:C>T,NM_130837.2:c.789+733C>T,\N,\N,7/30,Benign,\N,intron_variant,2.548,0.0862,1KG_AFR_AF,OPA1
608420,3:193344732:C>A,NM_130837.2:c.789+741C>A,\N,\N,7/30,Benign,\N,intron_variant,3.494,0.1051,1KG_AFR_AF,OPA1
608421,3:193344755:C>CTT,NM_130837.2:c.789+767_789+768dup,\N,\N,7/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
608422,3:193344801:C>G,NM_130837.2:c.789+810C>G,\N,\N,7/30,Unknown significance,\N,intron_variant,12.82,\N,\N,OPA1
608423,3:193344821:A>G,NM_130837.2:c.789+830A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,10.76,\N,\N,OPA1
608424,3:193344836:T>G,NM_130837.2:c.789+845T>G,\N,\N,7/30,Unknown significance,\N,intron_variant,3.498,\N,\N,OPA1
608425,3:193344874:T>G,NM_130837.2:c.789+883T>G,\N,\N,7/30,Unknown significance,\N,intron_variant,5.643,\N,\N,OPA1
608426,3:193344934:A>G,NM_130837.2:c.789+943A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,2.386,\N,\N,OPA1
608427,3:193344935:T>C,NM_130837.2:c.789+944T>C,\N,\N,7/30,Unknown significance,\N,intron_variant,6.17,0.001,1KG_EAS_AF,OPA1
608428,3:193344940:T>C,NM_130837.2:c.789+949T>C,\N,\N,7/30,Benign,\N,intron_variant,2.075,0.0212,1KG_AFR_AF,OPA1
608429,3:193344943:A>T,NM_130837.2:c.789+952A>T,\N,\N,7/30,Unknown significance,\N,intron_variant,0.965,0.001,1KG_SAS_AF,OPA1
608430,3:193344955:T>C,NM_130837.2:c.789+964T>C,\N,\N,7/30,Benign,\N,intron_variant,3.875,0.1484,1KG_AMR_AF,OPA1
608431,3:193344979:T>A,NM_130837.2:c.789+988T>A,\N,\N,7/30,Benign,\N,intron_variant,5.188,0.0257,1KG_AFR_AF,OPA1
608432,3:193344982:C>T,NM_130837.2:c.789+991C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,5.095,0.001,1KG_EAS_AF,OPA1
608433,3:193344994:T>C,NM_130837.2:c.789+1003T>C,\N,\N,7/30,Unknown significance,\N,intron_variant,12.1,\N,\N,OPA1
608434,3:193345013:C>T,NR_046634.1:n.104+5G>A,\N,\N,1/2,Unknown significance,\N,splice_region_variant&intron_variant&non_coding_transcript_variant,4.202,0.0008,1KG_AFR_AF,OPA1
608435,3:193345075:T>G,NM_130837.2:c.789+1084T>G,\N,\N,7/30,Unknown significance,\N,intron_variant,17.67,0.001,1KG_SAS_AF,OPA1
608436,3:193345104:C>T,NM_130837.2:c.789+1113C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,6.974,0.0014,1KG_AMR_AF,OPA1
608437,3:193345120:A>C,NM_130837.2:c.789+1129A>C,\N,\N,7/30,Unknown significance,\N,intron_variant,7.917,0.001,1KG_EUR_AF,OPA1
608438,3:193345122:C>T,NM_130837.2:c.789+1131C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,11.39,0.001,1KG_EAS_AF,OPA1
608439,3:193345166:G>A,NM_130837.2:c.789+1175G>A,\N,\N,7/30,Unknown significance,\N,intron_variant,2.271,0.0023,1KG_AFR_AF,OPA1
608440,3:193345214:A>G,NM_130837.2:c.789+1223A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,3.653,0.002,1KG_EAS_AF,OPA1
608441,3:193345238:A>G,NM_130837.2:c.789+1247A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,0.896,0.0008,1KG_AFR_AF,OPA1
608442,3:193345284:C>T,NM_130837.2:c.789+1293C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,2.396,0.001,1KG_EAS_AF,OPA1
608443,3:193345302:A>C,NM_130837.2:c.789+1311A>C,\N,\N,7/30,Unknown significance,\N,intron_variant,4.191,0.001,1KG_EUR_AF,OPA1
608444,3:193345313:G>A,NM_130837.2:c.789+1322G>A,\N,\N,7/30,Unknown significance,\N,intron_variant,5.95,0.0008,1KG_AFR_AF,OPA1
608445,3:193345358:G>A,NM_130837.2:c.789+1367G>A,\N,\N,7/30,Unknown significance,\N,intron_variant,2.357,\N,\N,OPA1
608446,3:193345394:G>C,NM_130837.2:c.789+1403G>C,\N,\N,7/30,Unknown significance,\N,intron_variant,0.454,\N,\N,OPA1
608447,3:193345424:C>T,NM_130837.2:c.789+1433C>T,\N,\N,7/30,Benign,\N,intron_variant,6.238,0.0257,1KG_AFR_AF,OPA1
608448,3:193345453:A>G,NM_130837.2:c.789+1462A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,3.154,0.001,1KG_EAS_AF,OPA1
608449,3:193345472:T>C,NM_130837.2:c.789+1481T>C,\N,\N,7/30,Unknown significance,\N,intron_variant,12.53,\N,\N,OPA1
608450,3:193345476:T>A,NM_130837.2:c.789+1485T>A,\N,\N,7/30,Unknown significance,\N,intron_variant,12.58,\N,\N,OPA1
608451,3:193345515:A>G,NM_130837.2:c.789+1524A>G,\N,\N,7/30,Benign,\N,intron_variant,13.41,0.1044,1KG_AFR_AF,OPA1
608452,3:193345534:G>A,NM_130837.2:c.789+1543G>A,\N,\N,7/30,Unknown significance,\N,intron_variant,3.634,\N,\N,OPA1
608453,3:193345535:C>T,NM_130837.2:c.789+1544C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,4.112,0.0014,1KG_AMR_AF,OPA1
608454,3:193345563:A>G,NM_130837.2:c.789+1572A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,6.896,\N,\N,OPA1
608455,3:193345603:T>C,NM_130837.2:c.789+1612T>C,\N,\N,7/30,Unknown significance,\N,intron_variant,4.637,0.001,1KG_EUR_AF,OPA1
608456,3:193345663:G>A,NM_130837.2:c.789+1672G>A,\N,\N,7/30,Unknown significance,\N,intron_variant,1.674,0.0014,1KG_AMR_AF,OPA1
608457,3:193345715:C>A,NM_130837.2:c.789+1724C>A,\N,\N,7/30,Benign,\N,intron_variant,7.119,0.008,1KG_EUR_AF,OPA1
608458,3:193345777:A>G,NM_130837.2:c.789+1786A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,4.571,0.001,1KG_SAS_AF,OPA1
608459,3:193345804:C>T,NM_130837.2:c.789+1813C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,4.158,\N,\N,OPA1
608460,3:193345805:G>A,NM_130837.2:c.789+1814G>A,\N,\N,7/30,Unknown significance,\N,intron_variant,1.431,0.001,1KG_EAS_AF,OPA1
608461,3:193345814:T>C,NM_130837.2:c.789+1823T>C,\N,\N,7/30,Unknown significance,\N,intron_variant,3.41,0.001,1KG_EUR_AF,OPA1
608462,3:193345853:A>G,NM_130837.2:c.789+1862A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,4.746,0.001,1KG_EAS_AF,OPA1
608463,3:193345854:C>A,NM_130837.2:c.789+1863C>A,\N,\N,7/30,Unknown significance,\N,intron_variant,3.753,0.001,1KG_EAS_AF,OPA1
608464,3:193345871:C>T,NM_130837.2:c.789+1880C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,8.061,\N,\N,OPA1
608465,3:193345889:A>G,NM_130837.2:c.789+1898A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,2.031,\N,\N,OPA1
608466,3:193345921:C>T,NM_130837.2:c.789+1930C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,11.98,0.001,1KG_EAS_AF,OPA1
608467,3:193345946:G>C,NM_130837.2:c.789+1955G>C,\N,\N,7/30,Unknown significance,\N,intron_variant,0.852,0.0008,1KG_AFR_AF,OPA1
608468,3:193345957:C>T,NM_130837.2:c.789+1966C>T,\N,\N,7/30,Benign,\N,intron_variant,4.606,0.0053,1KG_AFR_AF,OPA1
608469,3:193345959:G>A,NM_130837.2:c.789+1968G>A,\N,\N,7/30,Unknown significance,\N,intron_variant,3.687,0.0008,1KG_AFR_AF,OPA1
608470,3:193346016:A>G,NM_130837.2:c.789+2025A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,1.699,0.0031,1KG_SAS_AF,OPA1
608471,3:193346027:C>A,NM_130837.2:c.789+2036C>A,\N,\N,7/30,Unknown significance,\N,intron_variant,18.61,0.002,1KG_SAS_AF,OPA1
608472,3:193346027:C>G,NM_130837.2:c.789+2036C>G,\N,\N,7/30,Unknown significance,\N,intron_variant,16.57,0.004,1KG_EAS_AF,OPA1
608473,3:193346045:A>T,NM_130837.2:c.789+2054A>T,\N,\N,7/30,Unknown significance,\N,intron_variant,5.8,\N,\N,OPA1
608474,3:193346064:T>TC,NM_130837.2:c.789+2076dup,\N,\N,7/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
608475,3:193346069:G>A,NM_130837.2:c.789+2078G>A,\N,\N,7/30,Unknown significance,\N,intron_variant,1.421,0.0008,1KG_AFR_AF,OPA1
608476,3:193346077:T>C,NM_130837.2:c.789+2086T>C,\N,\N,7/30,Unknown significance,\N,intron_variant,16.47,0.0014,1KG_AMR_AF,OPA1
608477,3:193346119:A>G,NM_130837.2:c.789+2128A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,8.624,\N,\N,OPA1
608478,3:193346209:G>T,NM_130837.2:c.789+2218G>T,\N,\N,7/30,Unknown significance,\N,intron_variant,2.507,0.0008,1KG_AFR_AF,OPA1
608479,3:193346226:G>C,NM_130837.2:c.789+2235G>C,\N,\N,7/30,Unknown significance,\N,intron_variant,1.965,\N,\N,OPA1
608480,3:193346255:G>T,NM_130837.2:c.789+2264G>T,\N,\N,7/30,Unknown significance,\N,intron_variant,18.04,\N,\N,OPA1
608481,3:193346293:T>C,NM_130837.2:c.789+2302T>C,\N,\N,7/30,Unknown significance,\N,intron_variant,21.9,\N,\N,OPA1
608482,3:193346314:C>T,NM_130837.2:c.789+2323C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,22.3,\N,\N,OPA1
608483,3:193346324:C>T,NM_130837.2:c.789+2333C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,22.5,0.0008,1KG_AFR_AF,OPA1
608484,3:193346325:G>A,NM_130837.2:c.789+2334G>A,\N,\N,7/30,Unknown significance,\N,intron_variant,22.1,\N,\N,OPA1
608485,3:193346354:G>A,NM_130837.2:c.789+2363G>A,\N,\N,7/30,Benign,\N,intron_variant,22.6,0.0257,1KG_AFR_AF,OPA1
608486,3:193346378:A>G,NM_130837.2:c.789+2387A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,21.3,0.001,1KG_EUR_AF,OPA1
608487,3:193346382:C>T,NM_130837.2:c.789+2391C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,22.1,0.0008,1KG_AFR_AF,OPA1
608488,3:193346386:T>A,NM_130837.2:c.789+2395T>A,\N,\N,7/30,Unknown significance,\N,intron_variant,22.8,0.001,1KG_EAS_AF,OPA1
608489,3:193346430:T>C,NM_130837.2:c.789+2439T>C,\N,\N,7/30,Unknown significance,\N,intron_variant,5.827,\N,\N,OPA1
608490,3:193346438:A>G,NM_130837.2:c.789+2447A>G,\N,\N,7/30,Benign,\N,intron_variant,7.68,0.0053,1KG_AFR_AF,OPA1
608491,3:193346443:T>C,NM_130837.2:c.789+2452T>C,\N,\N,7/30,Unknown significance,\N,intron_variant,3.506,0.0031,1KG_SAS_AF,OPA1
608492,3:193346494:A>C,NM_130837.2:c.789+2503A>C,\N,\N,7/30,Unknown significance,\N,intron_variant,4.695,\N,\N,OPA1
608493,3:193346592:A>C,NM_130837.2:c.789+2601A>C,\N,\N,7/30,Benign,\N,intron_variant,5.341,0.0204,1KG_SAS_AF,OPA1
608494,3:193346610:A>G,NM_130837.2:c.789+2619A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,4.366,\N,\N,OPA1
608495,3:193346613:T>C,NM_130837.2:c.789+2622T>C,\N,\N,7/30,Unknown significance,\N,intron_variant,3.463,0.0008,1KG_AFR_AF,OPA1
608496,3:193346623:G>A,NM_130837.2:c.789+2632G>A,\N,\N,7/30,Unknown significance,\N,intron_variant,2.939,0.001,1KG_EAS_AF,OPA1
608497,3:193346648:A>C,NM_130837.2:c.789+2657A>C,\N,\N,7/30,Benign,\N,intron_variant,0.44,0.6785,1KG_AFR_AF,OPA1
608498,3:193346682:A>G,NM_130837.2:c.789+2691A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,3.699,\N,\N,OPA1
608499,3:193346699:CTTTTA>C,NM_130837.2:c.790-2696_790-2692del,\N,\N,7/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
608500,3:193346725:G>T,NM_130837.2:c.790-2676G>T,\N,\N,7/30,Unknown significance,\N,intron_variant,1.477,\N,\N,OPA1
608501,3:193346732:C>T,NM_130837.2:c.790-2669C>T,\N,\N,7/30,Benign,\N,intron_variant,0.344,0.0179,1KG_EAS_AF,OPA1
608502,3:193346733:G>A,NM_130837.2:c.790-2668G>A,\N,\N,7/30,Benign,\N,intron_variant,2.341,0.005,1KG_EUR_AF,OPA1
608503,3:193346767:A>G,NM_130837.2:c.790-2634A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,4.382,0.0008,1KG_AFR_AF,OPA1
608504,3:193346805:C>T,NM_130837.2:c.790-2596C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,0.853,\N,\N,OPA1
608505,3:193346820:A>G,NM_130837.2:c.790-2581A>G,\N,\N,7/30,Benign,\N,intron_variant,1.883,0.0051,1KG_SAS_AF,OPA1
608506,3:193346838:G>A,NM_130837.2:c.790-2563G>A,\N,\N,7/30,Unknown significance,\N,intron_variant,1.786,\N,\N,OPA1
608507,3:193346921:C>T,NM_130837.2:c.790-2480C>T,\N,\N,7/30,Benign,\N,intron_variant,0.692,0.4274,1KG_EUR_AF,OPA1
608508,3:193346929:C>T,NM_130837.2:c.790-2472C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,0.244,\N,\N,OPA1
608509,3:193346943:C>T,NM_130837.2:c.790-2458C>T,\N,\N,7/30,Benign,\N,intron_variant,0.455,0.0389,1KG_AMR_AF,OPA1
608510,3:193346945:G>T,NM_130837.2:c.790-2456G>T,\N,\N,7/30,Unknown significance,\N,intron_variant,0.734,0.0015,1KG_AFR_AF,OPA1
608511,3:193347024:A>G,NM_130837.2:c.790-2377A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,1.986,\N,\N,OPA1
608512,3:193347055:C>T,NM_130837.2:c.790-2346C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,5.086,\N,\N,OPA1
608513,3:193347056:G>A,NM_130837.2:c.790-2345G>A,\N,\N,7/30,Unknown significance,\N,intron_variant,0.664,\N,\N,OPA1
608514,3:193347098:G>T,NM_130837.2:c.790-2303G>T,\N,\N,7/30,Unknown significance,\N,intron_variant,8.409,\N,\N,OPA1
608515,3:193347107:A>G,NM_130837.2:c.790-2294A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,12.67,0.001,1KG_SAS_AF,OPA1
608516,3:193347151:C>G,NM_130837.2:c.790-2250C>G,\N,\N,7/30,Unknown significance,\N,intron_variant,7.156,\N,\N,OPA1
608517,3:193347166:C>A,NM_130837.2:c.790-2235C>A,\N,\N,7/30,Unknown significance,\N,intron_variant,5.64,0.0008,1KG_AFR_AF,OPA1
608518,3:193347176:T>C,NM_130837.2:c.790-2225T>C,\N,\N,7/30,Unknown significance,\N,intron_variant,2.108,\N,\N,OPA1
608519,3:193347198:T>C,NM_130837.2:c.790-2203T>C,\N,\N,7/30,Unknown significance,\N,intron_variant,1.29,\N,\N,OPA1
608520,3:193347208:C>T,NM_130837.2:c.790-2193C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,1.813,\N,\N,OPA1
608521,3:193347215:C>T,NM_130837.2:c.790-2186C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,1.01,\N,\N,OPA1
608522,3:193347216:G>A,NM_130837.2:c.790-2185G>A,\N,\N,7/30,Unknown significance,\N,intron_variant,2.22,0.003,1KG_EAS_AF,OPA1
608523,3:193347246:G>A,NM_130837.2:c.790-2155G>A,\N,\N,7/30,Unknown significance,\N,intron_variant,0.573,0.001,1KG_SAS_AF,OPA1
608524,3:193347253:T>C,NM_130837.2:c.790-2148T>C,\N,\N,7/30,Benign,\N,intron_variant,0.536,1,1KG_EAS_AF,OPA1
608525,3:193347275:C>G,NM_130837.2:c.790-2126C>G,\N,\N,7/30,Unknown significance,\N,intron_variant,0.65,0.004,1KG_EAS_AF,OPA1
608526,3:193347283:C>A,NM_130837.2:c.790-2118C>A,\N,\N,7/30,Unknown significance,\N,intron_variant,1.938,0.001,1KG_EAS_AF,OPA1
608527,3:193347283:C>T,NM_130837.2:c.790-2118C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,1.278,\N,\N,OPA1
608528,3:193347357:C>T,NM_130837.2:c.790-2044C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,4.488,0.0014,1KG_AMR_AF,OPA1
608529,3:193347399:G>A,NM_130837.2:c.790-2002G>A,\N,\N,7/30,Unknown significance,\N,intron_variant,3.375,0.0008,1KG_AFR_AF,OPA1
608530,3:193347438:C>T,NM_130837.2:c.790-1963C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,4.483,0.002,1KG_EUR_AF,OPA1
608531,3:193347444:C>T,NM_130837.2:c.790-1957C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,3.791,\N,\N,OPA1
608532,3:193347463:AAAG>A,NM_130837.2:c.790-1935_790-1933del,\N,\N,7/30,Benign,\N,intron_variant,0.668,0.0189,1KG_AFR_AF,OPA1
608533,3:193347469:A>G,NM_130837.2:c.790-1932A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,2.315,0.0015,1KG_AFR_AF,OPA1
608534,3:193347469:A>T,NM_130837.2:c.790-1932A>T,\N,\N,7/30,Unknown significance,\N,intron_variant,0.876,\N,\N,OPA1
608535,3:193347497:A>G,NM_130837.2:c.790-1904A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,0.379,\N,\N,OPA1
608536,3:193347502:A>T,NM_130837.2:c.790-1899A>T,\N,\N,7/30,Unknown significance,\N,intron_variant,1.28,\N,\N,OPA1
608537,3:193347513:T>G,NM_130837.2:c.790-1888T>G,\N,\N,7/30,Unknown significance,\N,intron_variant,2.716,\N,\N,OPA1
608538,3:193347516:T>C,NM_130837.2:c.790-1885T>C,\N,\N,7/30,Benign,\N,intron_variant,3.474,0.0061,1KG_SAS_AF,OPA1
608539,3:193347533:A>G,NM_130837.2:c.790-1868A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,0.305,0.001,1KG_EAS_AF,OPA1
608540,3:193347560:C>T,NM_130837.2:c.790-1841C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,8.787,\N,\N,OPA1
608541,3:193347579:CCTAA>C,NM_130837.2:c.790-1819_790-1816del,\N,\N,7/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
608542,3:193347625:G>C,NM_130837.2:c.790-1776G>C,\N,\N,7/30,Unknown significance,\N,intron_variant,12.5,\N,\N,OPA1
608543,3:193347647:T>C,NM_130837.2:c.790-1754T>C,\N,\N,7/30,Unknown significance,\N,intron_variant,15.67,\N,\N,OPA1
608544,3:193347650:A>G,NM_130837.2:c.790-1751A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,10.94,0.001,1KG_SAS_AF,OPA1
608545,3:193347679:CAGTT>C,NM_130837.2:c.790-1718_790-1715del,\N,\N,7/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
608546,3:193347702:T>G,NM_130837.2:c.790-1699T>G,\N,\N,7/30,Benign,\N,intron_variant,12.54,0.0179,1KG_EAS_AF,OPA1
608547,3:193347716:C>G,NM_130837.2:c.790-1685C>G,\N,\N,7/30,Unknown significance,\N,intron_variant,8.895,0.0008,1KG_AFR_AF,OPA1
608548,3:193347794:C>T,NM_130837.2:c.790-1607C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,14.03,\N,\N,OPA1
608549,3:193347824:A>G,NM_130837.2:c.790-1577A>G,\N,\N,7/30,Benign,\N,intron_variant,0.06,0.0106,1KG_AFR_AF,OPA1
608550,3:193347839:G>C,NM_130837.2:c.790-1562G>C,\N,\N,7/30,Benign,\N,intron_variant,0.338,0.0308,1KG_EAS_AF,OPA1
608551,3:193347846:C>G,NM_130837.2:c.790-1555C>G,\N,\N,7/30,Unknown significance,\N,intron_variant,3.328,\N,\N,OPA1
608552,3:193347858:G>A,NM_130837.2:c.790-1543G>A,\N,\N,7/30,Unknown significance,\N,intron_variant,3.583,\N,\N,OPA1
608553,3:193347878:T>C,NM_130837.2:c.790-1523T>C,\N,\N,7/30,Unknown significance,\N,intron_variant,6.989,\N,\N,OPA1
608554,3:193347891:T>C,NM_130837.2:c.790-1510T>C,\N,\N,7/30,Unknown significance,\N,intron_variant,3.248,0.001,1KG_EAS_AF,OPA1
608555,3:193347910:T>C,NM_130837.2:c.790-1491T>C,\N,\N,7/30,Unknown significance,\N,intron_variant,3.39,\N,\N,OPA1
608556,3:193347952:C>T,NM_130837.2:c.790-1449C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,15.48,0.0015,1KG_AFR_AF,OPA1
608557,3:193347962:C>G,NM_130837.2:c.790-1439C>G,\N,\N,7/30,Unknown significance,\N,intron_variant,10.05,\N,\N,OPA1
608558,3:193347982:A>G,NM_130837.2:c.790-1419A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,10.3,0.001,1KG_EAS_AF,OPA1
608559,3:193347995:A>T,NM_130837.2:c.790-1406A>T,\N,\N,7/30,Unknown significance,\N,intron_variant,8.912,\N,\N,OPA1
608560,3:193348052:CT>C,NM_130837.2:c.790-1347del,\N,\N,7/30,Benign,\N,intron_variant,3.218,0.4284,1KG_EUR_AF,OPA1
608561,3:193348053:T>C,NM_130837.2:c.790-1348T>C,\N,\N,7/30,Unknown significance,\N,intron_variant,1.356,0.002,1KG_EUR_AF,OPA1
608562,3:193348078:T>C,NM_130837.2:c.790-1323T>C,\N,\N,7/30,Unknown significance,\N,intron_variant,0.103,\N,\N,OPA1
608563,3:193348114:C>G,NM_130837.2:c.790-1287C>G,\N,\N,7/30,Unknown significance,\N,intron_variant,1.911,0.001,1KG_EAS_AF,OPA1
608564,3:193348115:G>A,NM_130837.2:c.790-1286G>A,\N,\N,7/30,Unknown significance,\N,intron_variant,3.128,\N,\N,OPA1
608565,3:193348135:A>G,NM_130837.2:c.790-1266A>G,\N,\N,7/30,Benign,\N,intron_variant,2.687,0.0204,1KG_AFR_AF,OPA1
608566,3:193348138:C>G,NM_130837.2:c.790-1263C>G,\N,\N,7/30,Benign,\N,intron_variant,0.44,0.9871,1KG_AFR_AF,OPA1
608567,3:193348187:A>G,NM_130837.2:c.790-1214A>G,\N,\N,7/30,Benign,\N,intron_variant,0.34,0.0367,1KG_EAS_AF,OPA1
608568,3:193348205:T>G,NM_130837.2:c.790-1196T>G,\N,\N,7/30,Unknown significance,\N,intron_variant,0.188,\N,\N,OPA1
608569,3:193348234:C>T,NM_130837.2:c.790-1167C>T,\N,\N,7/30,Benign,\N,intron_variant,0.974,0.761,1KG_AFR_AF,OPA1
608570,3:193348240:A>C,NM_130837.2:c.790-1161A>C,\N,\N,7/30,Unknown significance,\N,intron_variant,0.686,0.001,1KG_SAS_AF,OPA1
608571,3:193348263:TTAAAA>T,NM_130837.2:c.790-1134_790-1130del,\N,\N,7/30,Benign,\N,intron_variant,2.451,0.1044,1KG_AFR_AF,OPA1
608572,3:193348297:T>C,NM_130837.2:c.790-1104T>C,\N,\N,7/30,Unknown significance,\N,intron_variant,5.814,0.0038,1KG_AFR_AF,OPA1
608573,3:193348320:A>G,NM_130837.2:c.790-1081A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,7.743,0.001,1KG_SAS_AF,OPA1
608574,3:193348383:A>G,NM_130837.2:c.790-1018A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,1.583,0.0008,1KG_AFR_AF,OPA1
608575,3:193348392:G>A,NM_130837.2:c.790-1009G>A,\N,\N,7/30,Unknown significance,\N,intron_variant,8.361,0.0015,1KG_AFR_AF,OPA1
608576,3:193348470:T>C,NM_130837.2:c.790-931T>C,\N,\N,7/30,Unknown significance,\N,intron_variant,18.1,0.001,1KG_SAS_AF,OPA1
608577,3:193348515:A>C,NM_130837.2:c.790-886A>C,\N,\N,7/30,Benign,\N,intron_variant,16.07,0.0367,1KG_EAS_AF,OPA1
608578,3:193348551:T>C,NM_130837.2:c.790-850T>C,\N,\N,7/30,Benign,\N,intron_variant,11.31,0.0348,1KG_AFR_AF,OPA1
608579,3:193348560:A>T,NM_130837.2:c.790-841A>T,\N,\N,7/30,Unknown significance,\N,intron_variant,0.263,\N,\N,OPA1
608580,3:193348626:G>A,NM_130837.2:c.790-775G>A,\N,\N,7/30,Unknown significance,\N,intron_variant,0.36,\N,\N,OPA1
608581,3:193348628:TATAAA>T,NM_130837.2:c.790-765_790-761del,\N,\N,7/30,Unknown significance,\N,intron_variant,7.337,\N,\N,OPA1
608582,3:193348642:G>GT,NM_130837.2:c.790-753dup,\N,\N,7/30,Unknown significance,\N,intron_variant,0.514,\N,\N,OPA1
608583,3:193348661:T>C,NM_130837.2:c.790-740T>C,\N,\N,7/30,Unknown significance,\N,intron_variant,1.563,\N,\N,OPA1
608584,3:193348703:A>G,NM_130837.2:c.790-698A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,20.7,0.0008,1KG_AFR_AF,OPA1
608585,3:193348765:A>G,NM_130837.2:c.790-636A>G,\N,\N,7/30,Benign,\N,intron_variant,12.34,0.0245,1KG_AMR_AF,OPA1
608586,3:193348781:T>C,NM_130837.2:c.790-620T>C,\N,\N,7/30,Unknown significance,\N,intron_variant,8.145,\N,\N,OPA1
608587,3:193348782:C>T,NM_130837.2:c.790-619C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,9.753,0.001,1KG_EUR_AF,OPA1
608588,3:193348799:G>A,NM_130837.2:c.790-602G>A,\N,\N,7/30,Unknown significance,\N,intron_variant,9.848,0.001,1KG_EAS_AF,OPA1
608589,3:193348888:A>G,NM_130837.2:c.790-513A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,1.585,0.001,1KG_EAS_AF,OPA1
608590,3:193348892:T>C,NM_130837.2:c.790-509T>C,\N,\N,7/30,Unknown significance,\N,intron_variant,4.156,0.001,1KG_SAS_AF,OPA1
608591,3:193348894:C>T,NM_130837.2:c.790-507C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,2.767,0.001,1KG_SAS_AF,OPA1
608592,3:193348905:G>T,NM_130837.2:c.790-496G>T,\N,\N,7/30,Unknown significance,\N,intron_variant,0.846,0.0015,1KG_AFR_AF,OPA1
608593,3:193348919:A>G,NM_130837.2:c.790-482A>G,\N,\N,7/30,Benign,\N,intron_variant,9.061,0.4284,1KG_EUR_AF,OPA1
608594,3:193348927:A>G,NM_130837.2:c.790-474A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,3.668,0.001,1KG_EUR_AF,OPA1
608595,3:193348941:T>C,NM_130837.2:c.790-460T>C,\N,\N,7/30,Benign,\N,intron_variant,1.401,0.0092,1KG_SAS_AF,OPA1
608596,3:193348976:C>A,NM_130837.2:c.790-425C>A,\N,\N,7/30,Unknown significance,\N,intron_variant,7.91,0.0015,1KG_AFR_AF,OPA1
608597,3:193349004:T>C,NM_130837.2:c.790-397T>C,\N,\N,7/30,Unknown significance,\N,intron_variant,1.512,0.0008,1KG_AFR_AF,OPA1
608598,3:193349052:C>T,NM_130837.2:c.790-349C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,2.467,0.001,1KG_EUR_AF,OPA1
608599,3:193349062:A>G,NM_130837.2:c.790-339A>G,\N,\N,7/30,Benign,\N,intron_variant,1.626,0.0492,1KG_AFR_AF,OPA1
608600,3:193349067:T>G,NM_130837.2:c.790-334T>G,\N,\N,7/30,Unknown significance,\N,intron_variant,5.416,\N,\N,OPA1
608601,3:193349106:G>A,NM_130837.2:c.790-295G>A,\N,\N,7/30,Unknown significance,\N,intron_variant,11.12,\N,\N,OPA1
608602,3:193349111:G>C,NM_130837.2:c.790-290G>C,\N,\N,7/30,Unknown significance,\N,intron_variant,7.404,0.001,1KG_SAS_AF,OPA1
608603,3:193349115:T>C,NM_130837.2:c.790-286T>C,\N,\N,7/30,Benign,\N,intron_variant,8.356,0.1044,1KG_AFR_AF,OPA1
608604,3:193349126:TA>T,NM_130837.2:c.790-273del,\N,\N,7/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
608605,3:193349152:A>G,NM_130837.2:c.790-249A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,10.7,0.0014,1KG_AMR_AF,OPA1
608606,3:193349197:C>T,NM_130837.2:c.790-204C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,2.391,\N,\N,OPA1
608607,3:193349240:TA>T,NM_130837.2:c.790-160del,\N,\N,7/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
608608,3:193349256:A>G,NM_130837.2:c.790-145A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,15.25,0.002,1KG_EAS_AF,OPA1
608609,3:193349272:A>G,NM_130837.2:c.790-129A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,13.39,0.001,1KG_EAS_AF,OPA1
608610,3:193349282:TTAAA>T,NM_130837.2:c.790-116_790-113del,\N,\N,7/30,Unknown significance,\N,intron_variant,7.895,0.0023,1KG_AFR_AF,OPA1
608611,3:193349336:T>A,NM_130837.2:c.790-65T>A,\N,\N,7/30,Unknown significance,\N,intron_variant,14.47,0.002,1KG_EAS_AF,OPA1
608612,3:193349350:C>T,NM_130837.2:c.790-51C>T,\N,\N,7/30,Unknown significance,\N,intron_variant,2.879,0.0000151823,EXAC_NFE_AF,OPA1
608613,3:193349351:A>G,NM_130837.2:c.790-50A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,1.296,0.000103691,EXAC_AFR_AF,OPA1
608614,3:193349358:A>G,NM_130837.2:c.790-43A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,2.778,0.0000151708,EXAC_NFE_AF,OPA1
608615,3:193349359:T>A,NM_130837.2:c.790-42T>A,\N,\N,7/30,Unknown significance,\N,intron_variant,5.944,0.0000606722,EXAC_SAS_AF,OPA1
608616,3:193349362:A>T,NM_130837.2:c.790-39A>T,\N,\N,7/30,Unknown significance,\N,intron_variant,2.449,0.000166834,EXAC_NFE_AF,OPA1
608617,3:193349368:T>C,NM_130837.2:c.790-33T>C,\N,\N,7/30,Unknown significance,\N,intron_variant,1.458,0.0000866401,EXAC_AMR_AF,OPA1
608618,3:193349376:A>G,NM_130837.2:c.790-25A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,5.667,0.0000865801,EXAC_AMR_AF,OPA1
608619,3:193349383:A>G,NM_130837.2:c.790-18A>G,\N,\N,7/30,Unknown significance,\N,intron_variant,11.73,0.00015124,EXAC_FIN_AF,OPA1
608620,3:193349397:T>A,NM_130837.2:c.790-4T>A,\N,\N,7/30,Unknown significance,\N,splice_region_variant&intron_variant,16.04,0.001,1KG_EAS_AF,OPA1
608621,3:193349404:TCAGA>T,NM_130837.2:c.796_799del,NP_570850.2:p.Asp266LysfsTer16,8/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,35,\N,\N,OPA1
608622,3:193349405:C>A,NM_130837.2:c.794C>A,NP_570850.2:p.Ser265Ter,8/31,\N,Pathogenic,Optic atrophy 1,stop_gained,39,\N,\N,OPA1
608623,3:193349409:CAA>C,NM_130837.2:c.800_801del,NP_570850.2:p.Lys267ArgfsTer4,8/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,35,0.00010012,EXAC_AFR_AF,OPA1
608624,3:193349409:CAAAG>C,NM_130837.2:c.800_803del,NP_570850.2:p.Lys267ArgfsTer15,8/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,35,\N,\N,OPA1
608625,3:193349411:AAG>A,NM_130837.2:c.804_805del,NP_570850.2:p.Lys269AsnfsTer2,8/31,\N,Pathogenic,Optic atrophy,frameshift_variant,35,\N,\N,OPA1
608626,3:193349419:A>G,NM_130837.2:c.808A>G,NP_570850.2:p.Ile270Val,8/31,\N,Unknown significance,\N,missense_variant,8.289,0.0000150525,EXAC_NFE_AF,OPA1
608627,3:193349420:T>C,NM_130837.2:c.809T>C,NP_570850.2:p.Ile270Thr,8/31,\N,Unknown significance,\N,missense_variant,21.5,0.0000605914,EXAC_SAS_AF,OPA1
608628,3:193349422:G>T,NM_130837.2:c.811G>T,NP_570850.2:p.Asp271Tyr,8/31,\N,Unknown significance,\N,missense_variant,25.5,0.000226963,EVS_AA_AF,OPA1
608629,3:193349431:C>T,NM_130837.2:c.820C>T,NP_570850.2:p.Gln274Ter,8/31,\N,Pathogenic,Optic neuropathy,stop_gained,40,\N,\N,OPA1
608630,3:193349441:T>C,NM_015560.2:c.665T>C,NP_056375.2:p.Leu222Pro,6/29,\N,Pathogenic,Optic atrophy 1,missense_variant,24.5,0.001,1KG_EUR_AF,OPA1
608631,3:193349444:T>G,NM_130837.2:c.833T>G,NP_570850.2:p.Leu278Arg,8/31,\N,Unknown significance,\N,missense_variant,32,0.0000987947,EXAC_AFR_AF,OPA1
608632,3:193349449:A>G,NM_130837.2:c.838A>G,NP_570850.2:p.Thr280Ala,8/31,\N,Unknown significance,\N,missense_variant,17.02,\N,\N,OPA1
608633,3:193349456:T>TA,NM_130837.2:c.843+4dup,\N,\N,8/30,Unknown significance,\N,splice_region_variant&intron_variant,15.6,0.000197746,EXAC_AFR_AF,OPA1
608634,3:193349461:A>G,NM_130837.2:c.843+7A>G,\N,\N,8/30,Unknown significance,\N,splice_region_variant&intron_variant,0.467,0.0000605914,EXAC_SAS_AF,OPA1
608635,3:193349463:G>C,NM_130837.2:c.843+9G>C,\N,\N,8/30,Unknown significance,\N,intron_variant,0.279,0.000015043,EXAC_NFE_AF,OPA1
608636,3:193349466:G>A,NM_130837.2:c.843+12G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,3.576,0.00011566,EXAC_EAS_AF,OPA1
608637,3:193349470:A>G,NM_130837.2:c.843+16A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,4.777,0.000121183,EXAC_SAS_AF,OPA1
608638,3:193349472:G>A,NM_130837.2:c.843+18G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,3.376,0.0000150476,EXAC_NFE_AF,OPA1
608639,3:193349477:A>T,NM_130837.2:c.843+23A>T,\N,\N,8/30,Unknown significance,\N,intron_variant,0.165,0.0000150489,EXAC_NFE_AF,OPA1
608640,3:193349478:C>G,NM_130837.2:c.843+24C>G,\N,\N,8/30,Unknown significance,\N,intron_variant,1.24,0.0008,1KG_AFR_AF,OPA1
608641,3:193349485:CTT>C,NM_130837.2:c.843+34_843+35del,\N,\N,8/30,Unknown significance,\N,intron_variant,5.791,0.000231481,EXAC_EAS_AF,OPA1
608642,3:193349488:T>C,NM_130837.2:c.843+34T>C,\N,\N,8/30,Unknown significance,\N,intron_variant,2.497,\N,\N,OPA1
608643,3:193349488:T>TATATGCA,NM_130837.2:c.843+34_843+35insATATGCA,\N,\N,8/30,Unknown significance,\N,intron_variant,1.016,\N,\N,OPA1
608644,3:193349494:A>T,NM_130837.2:c.843+40A>T,\N,\N,8/30,Unknown significance,\N,intron_variant,0.819,0.000015067,EXAC_NFE_AF,OPA1
608645,3:193349496:T>C,NM_130837.2:c.843+42T>C,\N,\N,8/30,Unknown significance,\N,intron_variant,3.991,0.0008,1KG_AFR_AF,OPA1
608646,3:193349502:C>T,NM_130837.2:c.843+48C>T,\N,\N,8/30,Unknown significance,\N,intron_variant,5.657,0.000231857,EXAC_EAS_AF,OPA1
608647,3:193349503:G>A,NM_130837.2:c.843+49G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,2.133,0.000903978,EXAC_AFR_AF,OPA1
608648,3:193349506:T>A,NM_130837.2:c.843+52T>A,\N,\N,8/30,Unknown significance,\N,intron_variant,7.671,0.0000603118,EXAC_NFE_AF,OPA1
608649,3:193349508:T>C,NM_130837.2:c.843+54T>C,\N,\N,8/30,Unknown significance,\N,intron_variant,4.039,0.001,1KG_SAS_AF,OPA1
608650,3:193349509:A>C,NM_130837.2:c.843+55A>C,\N,\N,8/30,Unknown significance,\N,intron_variant,3.44,\N,\N,OPA1
608651,3:193349585:C>T,NM_130837.2:c.843+131C>T,\N,\N,8/30,Unknown significance,\N,intron_variant,3.428,0.001,1KG_EUR_AF,OPA1
608652,3:193349599:G>A,NM_130837.2:c.843+145G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,14.38,\N,\N,OPA1
608653,3:193349639:T>C,NM_130837.2:c.843+185T>C,\N,\N,8/30,Unknown significance,\N,intron_variant,5.545,0.001,1KG_SAS_AF,OPA1
608654,3:193349662:T>G,NM_130837.2:c.843+208T>G,\N,\N,8/30,Unknown significance,\N,intron_variant,6.331,0.0023,1KG_AFR_AF,OPA1
608655,3:193349719:T>C,NM_130837.2:c.843+265T>C,\N,\N,8/30,Unknown significance,\N,intron_variant,2.622,\N,\N,OPA1
608656,3:193349720:A>G,NM_130837.2:c.843+266A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,1.359,\N,\N,OPA1
608657,3:193349728:A>G,NM_130837.2:c.843+274A>G,\N,\N,8/30,Benign,\N,intron_variant,4.234,0.007,1KG_EUR_AF,OPA1
608658,3:193349750:A>T,NM_130837.2:c.843+296A>T,\N,\N,8/30,Unknown significance,\N,intron_variant,8.245,\N,\N,OPA1
608659,3:193349770:A>G,NM_130837.2:c.843+316A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,13.41,0.001,1KG_EAS_AF,OPA1
608660,3:193349774:G>A,NM_130837.2:c.843+320G>A,\N,\N,8/30,Benign,\N,intron_variant,11.42,0.0212,1KG_AFR_AF,OPA1
608661,3:193349775:A>G,NM_130837.2:c.843+321A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,12.24,\N,\N,OPA1
608662,3:193349793:G>A,NM_130837.2:c.843+339G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,1.426,0.002,1KG_SAS_AF,OPA1
608663,3:193349802:G>A,NM_130837.2:c.843+348G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,0.218,0.001,1KG_EAS_AF,OPA1
608664,3:193349810:G>A,NM_130837.2:c.843+356G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,2.409,\N,\N,OPA1
608665,3:193349813:A>G,NM_130837.2:c.843+359A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,3.967,0.001,1KG_SAS_AF,OPA1
608666,3:193349828:C>T,NM_130837.2:c.843+374C>T,\N,\N,8/30,Unknown significance,\N,intron_variant,6.509,0.001,1KG_SAS_AF,OPA1
608667,3:193349988:C>T,NM_130837.2:c.843+534C>T,\N,\N,8/30,Unknown significance,\N,intron_variant,4.703,\N,\N,OPA1
608668,3:193349998:C>T,NM_130837.2:c.843+544C>T,\N,\N,8/30,Benign,\N,intron_variant,0.266,0.007,1KG_EUR_AF,OPA1
608669,3:193350006:C>T,NM_130837.2:c.843+552C>T,\N,\N,8/30,Unknown significance,\N,intron_variant,2.971,0.001,1KG_EAS_AF,OPA1
608670,3:193350009:G>A,NM_130837.2:c.843+555G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,0.627,0.001,1KG_EUR_AF,OPA1
608671,3:193350013:G>A,NM_130837.2:c.843+559G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,2.766,0.0015,1KG_AFR_AF,OPA1
608672,3:193350013:G>C,NM_130837.2:c.843+559G>C,\N,\N,8/30,Unknown significance,\N,intron_variant,0.887,\N,\N,OPA1
608673,3:193350020:C>T,NM_130837.2:c.843+566C>T,\N,\N,8/30,Unknown significance,\N,intron_variant,3.901,\N,\N,OPA1
608674,3:193350021:A>G,NM_130837.2:c.843+567A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,3.092,\N,\N,OPA1
608675,3:193350023:C>T,NM_130837.2:c.843+569C>T,\N,\N,8/30,Unknown significance,\N,intron_variant,3.794,0.0008,1KG_AFR_AF,OPA1
608676,3:193350026:T>A,NM_130837.2:c.843+572T>A,\N,\N,8/30,Unknown significance,\N,intron_variant,6.766,\N,\N,OPA1
608677,3:193350045:C>T,NM_130837.2:c.843+591C>T,\N,\N,8/30,Unknown significance,\N,intron_variant,0.467,0.001,1KG_EUR_AF,OPA1
608678,3:193350051:A>T,NM_130837.2:c.843+597A>T,\N,\N,8/30,Unknown significance,\N,intron_variant,1.054,\N,\N,OPA1
608679,3:193350059:A>G,NM_130837.2:c.843+605A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,1.796,\N,\N,OPA1
608680,3:193350067:G>C,NM_130837.2:c.843+613G>C,\N,\N,8/30,Benign,\N,intron_variant,0.036,0.0101,1KG_AMR_AF,OPA1
608681,3:193350087:A>G,NM_130837.2:c.843+633A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,0.059,0.0015,1KG_AFR_AF,OPA1
608682,3:193350119:A>T,NM_130837.2:c.843+665A>T,\N,\N,8/30,Unknown significance,\N,intron_variant,0.303,0.0014,1KG_AMR_AF,OPA1
608683,3:193350174:G>A,NM_130837.2:c.843+720G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,5.145,\N,\N,OPA1
608684,3:193350180:G>A,NM_130837.2:c.843+726G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,3.538,\N,\N,OPA1
608685,3:193350202:G>A,NM_130837.2:c.843+748G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,0.131,0.001,1KG_SAS_AF,OPA1
608686,3:193350212:G>C,NM_130837.2:c.843+758G>C,\N,\N,8/30,Unknown significance,\N,intron_variant,0.491,\N,\N,OPA1
608687,3:193350221:G>A,NM_130837.2:c.843+767G>A,\N,\N,8/30,Benign,\N,intron_variant,0.206,0.1511,1KG_EUR_AF,OPA1
608688,3:193350227:G>A,NM_130837.2:c.843+773G>A,\N,\N,8/30,Benign,\N,intron_variant,0.144,0.0153,1KG_SAS_AF,OPA1
608689,3:193350248:C>T,NM_130837.2:c.843+794C>T,\N,\N,8/30,Unknown significance,\N,intron_variant,1.847,0,1KG_ALL_AF|1KG_AFR_AF|1KG_AMR_AF|1KG_EAS_AF|1KG_EUR_AF|1KG_SAS_AF,OPA1
608690,3:193350275:G>GA,NM_130837.2:c.843+829dup,\N,\N,8/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
608691,3:193350294:T>C,NM_130837.2:c.843+840T>C,\N,\N,8/30,Benign,\N,intron_variant,0.475,0.6112,1KG_AFR_AF,OPA1
608692,3:193350300:A>G,NM_130837.2:c.843+846A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,1.816,\N,\N,OPA1
608693,3:193350384:A>G,NM_130837.2:c.843+930A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,6.694,\N,\N,OPA1
608694,3:193350385:T>C,NM_130837.2:c.843+931T>C,\N,\N,8/30,Unknown significance,\N,intron_variant,5.995,\N,\N,OPA1
608695,3:193350386:G>A,NM_130837.2:c.843+932G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,7.387,\N,\N,OPA1
608696,3:193350386:G>T,NM_130837.2:c.843+932G>T,\N,\N,8/30,Unknown significance,\N,intron_variant,4.393,0.0031,1KG_SAS_AF,OPA1
608697,3:193350391:G>C,NM_130837.2:c.843+937G>C,\N,\N,8/30,Unknown significance,\N,intron_variant,1.128,\N,\N,OPA1
608698,3:193350395:T>C,NM_130837.2:c.843+941T>C,\N,\N,8/30,Benign,\N,intron_variant,7.806,0.0076,1KG_AFR_AF,OPA1
608699,3:193350398:C>T,NM_130837.2:c.843+944C>T,\N,\N,8/30,Unknown significance,\N,intron_variant,9.024,\N,\N,OPA1
608700,3:193350400:G>A,NM_130837.2:c.843+946G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,8.505,\N,\N,OPA1
608701,3:193350407:C>T,NM_130837.2:c.843+953C>T,\N,\N,8/30,Unknown significance,\N,intron_variant,8.387,\N,\N,OPA1
608702,3:193350415:T>TC,NM_130837.2:c.843+961_843+962insC,\N,\N,8/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
608703,3:193350417:A>G,NM_130837.2:c.843+963A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,0.891,\N,\N,OPA1
608704,3:193350423:T>C,NM_130837.2:c.843+969T>C,\N,\N,8/30,Unknown significance,\N,intron_variant,2.04,\N,\N,OPA1
608705,3:193350424:G>A,NM_130837.2:c.843+970G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,2.061,\N,\N,OPA1
608706,3:193350427:G>A,NM_130837.2:c.843+973G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,2.882,\N,\N,OPA1
608707,3:193350428:C>T,NM_130837.2:c.843+974C>T,\N,\N,8/30,Unknown significance,\N,intron_variant,3.03,\N,\N,OPA1
608708,3:193350429:A>C,NM_130837.2:c.843+975A>C,\N,\N,8/30,Unknown significance,\N,intron_variant,1.274,\N,\N,OPA1
608709,3:193350438:G>A,NM_130837.2:c.843+984G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,0.397,\N,\N,OPA1
608710,3:193350464:C>T,NM_130837.2:c.843+1010C>T,\N,\N,8/30,Unknown significance,\N,intron_variant,7.503,\N,\N,OPA1
608711,3:193350476:G>A,NM_130837.2:c.843+1022G>A,\N,\N,8/30,Benign,\N,intron_variant,0.913,0.0099,1KG_EUR_AF,OPA1
608712,3:193350500:T>A,NM_130837.2:c.843+1046T>A,\N,\N,8/30,Benign,\N,intron_variant,5.944,0.584,1KG_AFR_AF,OPA1
608713,3:193350501:T>A,NM_130837.2:c.843+1047T>A,\N,\N,8/30,Unknown significance,\N,intron_variant,3.304,0.0008,1KG_AFR_AF,OPA1
608714,3:193350520:G>A,NM_130837.2:c.843+1066G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,2.258,0.003,1KG_EAS_AF,OPA1
608715,3:193350568:AG>A,NM_130837.2:c.843+1116del,\N,\N,8/30,Benign,\N,intron_variant,0.83,0.0133,1KG_SAS_AF,OPA1
608716,3:193350585:A>C,NM_130837.2:c.843+1131A>C,\N,\N,8/30,Unknown significance,\N,intron_variant,0.329,\N,\N,OPA1
608717,3:193350609:A>G,NM_130837.2:c.843+1155A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,0.483,\N,\N,OPA1
608718,3:193350630:G>A,NM_130837.2:c.843+1176G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,2.143,\N,\N,OPA1
608719,3:193350679:A>C,NM_130837.2:c.843+1225A>C,\N,\N,8/30,Unknown significance,\N,intron_variant,0.003,\N,\N,OPA1
608720,3:193350689:C>A,NM_130837.2:c.843+1235C>A,\N,\N,8/30,Unknown significance,\N,intron_variant,5.824,\N,\N,OPA1
608721,3:193350691:C>CT,NM_130837.2:c.843+1243dup,\N,\N,8/30,Unknown significance,\N,intron_variant,5.641,\N,\N,OPA1
608722,3:193350713:G>A,NM_130837.2:c.843+1259G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,0.425,0.0029,1KG_AMR_AF,OPA1
608723,3:193350714:A>T,NM_130837.2:c.843+1260A>T,\N,\N,8/30,Benign,\N,intron_variant,1.591,0.0159,1KG_AFR_AF,OPA1
608724,3:193350717:A>G,NM_130837.2:c.843+1263A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,2.604,\N,\N,OPA1
608725,3:193350721:G>A,NM_130837.2:c.843+1267G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,2.104,0.004,1KG_EUR_AF,OPA1
608726,3:193350723:T>C,NM_130837.2:c.843+1269T>C,\N,\N,8/30,Unknown significance,\N,intron_variant,1.202,\N,\N,OPA1
608727,3:193350726:A>C,NM_130837.2:c.843+1272A>C,\N,\N,8/30,Unknown significance,\N,intron_variant,0.089,0.0008,1KG_AFR_AF,OPA1
608728,3:193350736:T>C,NM_130837.2:c.843+1282T>C,\N,\N,8/30,Unknown significance,\N,intron_variant,1.292,\N,\N,OPA1
608729,3:193350737:C>G,NM_130837.2:c.843+1283C>G,\N,\N,8/30,Unknown significance,\N,intron_variant,1.349,\N,\N,OPA1
608730,3:193350737:C>T,NM_130837.2:c.843+1283C>T,\N,\N,8/30,Unknown significance,\N,intron_variant,1.821,0.001,1KG_EUR_AF,OPA1
608731,3:193350740:A>T,NM_130837.2:c.843+1286A>T,\N,\N,8/30,Unknown significance,\N,intron_variant,1.586,0.002,1KG_SAS_AF,OPA1
608732,3:193350743:T>A,NM_130837.2:c.843+1289T>A,\N,\N,8/30,Unknown significance,\N,intron_variant,5.523,0.0008,1KG_AFR_AF,OPA1
608733,3:193350752:C>T,NM_130837.2:c.843+1298C>T,\N,\N,8/30,Unknown significance,\N,intron_variant,4.263,\N,\N,OPA1
608734,3:193350814:T>C,NM_130837.2:c.843+1360T>C,\N,\N,8/30,Unknown significance,\N,intron_variant,3.21,0.0015,1KG_AFR_AF,OPA1
608735,3:193350837:T>G,NM_130837.2:c.843+1383T>G,\N,\N,8/30,Benign,\N,intron_variant,5.117,0.4274,1KG_EUR_AF,OPA1
608736,3:193350848:C>G,NM_130837.2:c.843+1394C>G,\N,\N,8/30,Unknown significance,\N,intron_variant,1.051,0.001,1KG_EUR_AF,OPA1
608737,3:193350875:T>A,NM_130837.2:c.843+1421T>A,\N,\N,8/30,Unknown significance,\N,intron_variant,5.788,0.001,1KG_EAS_AF,OPA1
608738,3:193350875:T>G,NM_130837.2:c.843+1421T>G,\N,\N,8/30,Unknown significance,\N,intron_variant,4.151,\N,\N,OPA1
608739,3:193350876:G>T,NM_130837.2:c.843+1422G>T,\N,\N,8/30,Benign,\N,intron_variant,0.934,0.4284,1KG_EUR_AF,OPA1
608740,3:193350890:A>ACTATAT,NM_130837.2:c.843+1441_843+1446dup,\N,\N,8/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
608741,3:193350890:ACTATAT>A,NM_130837.2:c.843+1441_843+1446del,\N,\N,8/30,Benign,\N,intron_variant,6.897,0.4284,1KG_EUR_AF,OPA1
608742,3:193350893:ATATC>A,NM_130837.2:c.843+1443_843+1446del,\N,\N,8/30,Unknown significance,\N,intron_variant,6.558,\N,\N,OPA1
608743,3:193350909:G>A,NM_130837.2:c.843+1455G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,2.605,0.001,1KG_EUR_AF,OPA1
608744,3:193350956:T>C,NM_130837.2:c.843+1502T>C,\N,\N,8/30,Unknown significance,\N,intron_variant,0.338,\N,\N,OPA1
608745,3:193350986:T>A,NM_130837.2:c.843+1532T>A,\N,\N,8/30,Unknown significance,\N,intron_variant,5.796,\N,\N,OPA1
608746,3:193350998:A>G,NM_130837.2:c.843+1544A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,3.654,0.001,1KG_EAS_AF,OPA1
608747,3:193351070:T>G,NM_130837.2:c.843+1616T>G,\N,\N,8/30,Unknown significance,\N,intron_variant,0.824,\N,\N,OPA1
608748,3:193351098:A>G,NM_130837.2:c.843+1644A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,5.975,0.002,1KG_EAS_AF,OPA1
608749,3:193351107:G>C,NM_130837.2:c.843+1653G>C,\N,\N,8/30,Unknown significance,\N,intron_variant,2.007,0.0008,1KG_AFR_AF,OPA1
608750,3:193351141:A>G,NM_130837.2:c.843+1687A>G,\N,\N,8/30,Benign,\N,intron_variant,0.834,0.0159,1KG_AFR_AF,OPA1
608751,3:193351147:C>T,NM_130837.2:c.843+1693C>T,\N,\N,8/30,Unknown significance,\N,intron_variant,1.215,\N,\N,OPA1
608752,3:193351183:C>T,NM_130837.2:c.843+1729C>T,\N,\N,8/30,Unknown significance,\N,intron_variant,8.217,\N,\N,OPA1
608753,3:193351215:C>T,NM_130837.2:c.843+1761C>T,\N,\N,8/30,Unknown significance,\N,intron_variant,3.131,0.001,1KG_SAS_AF,OPA1
608754,3:193351300:G>T,NM_130837.2:c.843+1846G>T,\N,\N,8/30,Unknown significance,\N,intron_variant,0.296,\N,\N,OPA1
608755,3:193351317:T>A,NM_130837.2:c.843+1863T>A,\N,\N,8/30,Unknown significance,\N,intron_variant,6.341,\N,\N,OPA1
608756,3:193351321:T>C,NM_130837.2:c.843+1867T>C,\N,\N,8/30,Unknown significance,\N,intron_variant,3.115,0.0014,1KG_AMR_AF,OPA1
608757,3:193351414:AT>A,NM_130837.2:c.844-1788del,\N,\N,8/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
608758,3:193351438:AAG>A,NM_130837.2:c.844-1767_844-1766del,\N,\N,8/30,Unknown significance,\N,intron_variant,0.251,\N,\N,OPA1
608759,3:193351445:G>A,NM_130837.2:c.844-1762G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,0.516,0.0031,1KG_SAS_AF,OPA1
608760,3:193351461:T>G,NM_130837.2:c.844-1746T>G,\N,\N,8/30,Unknown significance,\N,intron_variant,6.401,\N,\N,OPA1
608761,3:193351485:C>T,NM_130837.2:c.844-1722C>T,\N,\N,8/30,Unknown significance,\N,intron_variant,3.039,\N,\N,OPA1
608762,3:193351527:A>G,NM_130837.2:c.844-1680A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,5.198,\N,\N,OPA1
608763,3:193351629:A>AG,NM_130837.2:c.844-1577dup,\N,\N,8/30,Benign,\N,intron_variant,0.416,0.0166,1KG_AFR_AF,OPA1
608764,3:193351684:A>C,NM_130837.2:c.844-1523A>C,\N,\N,8/30,Unknown significance,\N,intron_variant,1.473,\N,\N,OPA1
608765,3:193351731:G>T,NM_130837.2:c.844-1476G>T,\N,\N,8/30,Unknown significance,\N,intron_variant,3.352,\N,\N,OPA1
608766,3:193351756:TA>T,NM_130837.2:c.844-1450del,\N,\N,8/30,Benign,\N,intron_variant,4.817,0.0179,1KG_EAS_AF,OPA1
608767,3:193351758:G>T,NM_130837.2:c.844-1449G>T,\N,\N,8/30,Benign,\N,intron_variant,0.123,0.0179,1KG_EAS_AF,OPA1
608768,3:193351759:G>C,NM_130837.2:c.844-1448G>C,\N,\N,8/30,Benign,\N,intron_variant,0.12,0.0179,1KG_EAS_AF,OPA1
608769,3:193351761:G>T,NM_130837.2:c.844-1446G>T,\N,\N,8/30,Benign,\N,intron_variant,1.166,0.0179,1KG_EAS_AF,OPA1
608770,3:193351778:T>C,NM_130837.2:c.844-1429T>C,\N,\N,8/30,Unknown significance,\N,intron_variant,4.937,0.001,1KG_EAS_AF,OPA1
608771,3:193351795:G>C,NM_130837.2:c.844-1412G>C,\N,\N,8/30,Unknown significance,\N,intron_variant,9.561,\N,\N,OPA1
608772,3:193351796:A>G,NM_130837.2:c.844-1411A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,12.22,0.001,1KG_EAS_AF,OPA1
608773,3:193351806:G>T,NM_130837.2:c.844-1401G>T,\N,\N,8/30,Unknown significance,\N,intron_variant,1.621,0.002,1KG_SAS_AF,OPA1
608774,3:193351818:G>A,NM_130837.2:c.844-1389G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,2.906,0.001,1KG_EAS_AF,OPA1
608775,3:193351836:A>G,NM_130837.2:c.844-1371A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,10.21,0.001,1KG_EUR_AF,OPA1
608776,3:193351868:T>TA,NM_130837.2:c.844-1332dup,\N,\N,8/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
608777,3:193351906:A>G,NM_130837.2:c.844-1301A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,7.791,\N,\N,OPA1
608778,3:193351980:A>G,NM_130837.2:c.844-1227A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,4.318,0.001,1KG_EAS_AF,OPA1
608779,3:193352017:T>C,NM_130837.2:c.844-1190T>C,\N,\N,8/30,Unknown significance,\N,intron_variant,6.633,0.002,1KG_SAS_AF,OPA1
608780,3:193352042:C>T,NM_130837.2:c.844-1165C>T,\N,\N,8/30,Benign,\N,intron_variant,0.946,0.0367,1KG_EAS_AF,OPA1
608781,3:193352071:C>A,NM_130837.2:c.844-1136C>A,\N,\N,8/30,Unknown significance,\N,intron_variant,0.247,\N,\N,OPA1
608782,3:193352071:C>CA,NM_130837.2:c.844-1126dup,\N,\N,8/30,Unknown significance,\N,intron_variant,0.618,\N,\N,OPA1
608783,3:193352071:C>CAA,NM_130837.2:c.844-1127_844-1126dup,\N,\N,8/30,Unknown significance,\N,intron_variant,0.568,\N,\N,OPA1
608784,3:193352073:A>AAAC,NM_130837.2:c.844-1132_844-1131insCAA,\N,\N,8/30,Benign,\N,intron_variant,0.42,0.005,1KG_EUR_AF,OPA1
608785,3:193352093:A>G,NM_130837.2:c.844-1114A>G,\N,\N,8/30,Benign,\N,intron_variant,1.046,0.0367,1KG_EAS_AF,OPA1
608786,3:193352112:A>G,NM_130837.2:c.844-1095A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,1.281,\N,\N,OPA1
608787,3:193352143:G>A,NM_130837.2:c.844-1064G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,0.191,0.001,1KG_EAS_AF,OPA1
608788,3:193352143:GTGTTT>G,NM_130837.2:c.844-1052_844-1048del,\N,\N,8/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
608789,3:193352154:TG>T,NM_130837.2:c.844-1052del,\N,\N,8/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
608790,3:193352155:G>GT,NM_130837.2:c.844-1045dup,\N,\N,8/30,Benign,\N,intron_variant,0.362,0.0061,1KG_AFR_AF,OPA1
608791,3:193352160:T>G,NM_130837.2:c.844-1047T>G,\N,\N,8/30,Unknown significance,\N,intron_variant,0.756,0.001,1KG_EUR_AF,OPA1
608792,3:193352170:A>G,NM_130837.2:c.844-1037A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,1.613,0.001,1KG_SAS_AF,OPA1
608793,3:193352189:T>C,NM_130837.2:c.844-1018T>C,\N,\N,8/30,Unknown significance,\N,intron_variant,3.755,0.001,1KG_EUR_AF,OPA1
608794,3:193352226:T>C,NM_130837.2:c.844-981T>C,\N,\N,8/30,Unknown significance,\N,intron_variant,4.46,0.0015,1KG_AFR_AF,OPA1
608795,3:193352280:C>T,NM_130837.2:c.844-927C>T,\N,\N,8/30,Benign,\N,intron_variant,2.218,0.006,1KG_EUR_AF,OPA1
608796,3:193352281:G>A,NM_130837.2:c.844-926G>A,\N,\N,8/30,Benign,\N,intron_variant,1.27,0.0367,1KG_EAS_AF,OPA1
608797,3:193352292:C>T,NM_130837.2:c.844-915C>T,\N,\N,8/30,Unknown significance,\N,intron_variant,0.392,0.0014,1KG_AMR_AF,OPA1
608798,3:193352300:G>A,NM_130837.2:c.844-907G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,3.446,0.0023,1KG_AFR_AF,OPA1
608799,3:193352344:C>T,NM_130837.2:c.844-863C>T,\N,\N,8/30,Unknown significance,\N,intron_variant,2.555,\N,\N,OPA1
608800,3:193352351:T>C,NM_130837.2:c.844-856T>C,\N,\N,8/30,Unknown significance,\N,intron_variant,0.252,\N,\N,OPA1
608801,3:193352353:C>G,NM_130837.2:c.844-854C>G,\N,\N,8/30,Unknown significance,\N,intron_variant,1.497,\N,\N,OPA1
608802,3:193352360:C>T,NM_130837.2:c.844-847C>T,\N,\N,8/30,Benign,\N,intron_variant,1.225,0.1051,1KG_AFR_AF,OPA1
608803,3:193352363:C>T,NM_130837.2:c.844-844C>T,\N,\N,8/30,Unknown significance,\N,intron_variant,0.54,0.0008,1KG_AFR_AF,OPA1
608804,3:193352364:G>A,NM_130837.2:c.844-843G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,2.657,\N,\N,OPA1
608805,3:193352372:A>G,NM_130837.2:c.844-835A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,2.187,0.001,1KG_EUR_AF,OPA1
608806,3:193352384:A>G,NM_130837.2:c.844-823A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,2.663,0.002,1KG_SAS_AF,OPA1
608807,3:193352389:G>A,NM_130837.2:c.844-818G>A,\N,\N,8/30,Benign,\N,intron_variant,5.099,0.0726,1KG_AFR_AF,OPA1
608808,3:193352390:G>C,NM_130837.2:c.844-817G>C,\N,\N,8/30,Unknown significance,\N,intron_variant,1.353,0.0014,1KG_AMR_AF,OPA1
608809,3:193352391:G>T,NM_130837.2:c.844-816G>T,\N,\N,8/30,Unknown significance,\N,intron_variant,1.751,\N,\N,OPA1
608810,3:193352399:A>G,NM_130837.2:c.844-808A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,3.39,\N,\N,OPA1
608811,3:193352401:G>A,NM_130837.2:c.844-806G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,2.918,0.0014,1KG_AMR_AF,OPA1
608812,3:193352404:G>A,NM_130837.2:c.844-803G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,2.583,\N,\N,OPA1
608813,3:193352408:A>G,NM_130837.2:c.844-799A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,2.802,\N,\N,OPA1
608814,3:193352410:A>G,NM_130837.2:c.844-797A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,0.456,\N,\N,OPA1
608815,3:193352413:G>A,NM_130837.2:c.844-794G>A,\N,\N,8/30,Benign,\N,intron_variant,2.859,0.006,1KG_EUR_AF,OPA1
608816,3:193352414:C>G,NM_130837.2:c.844-793C>G,\N,\N,8/30,Unknown significance,\N,intron_variant,0.43,\N,\N,OPA1
608817,3:193352415:T>G,NM_130837.2:c.844-792T>G,\N,\N,8/30,Unknown significance,\N,intron_variant,3.073,0.0014,1KG_AMR_AF,OPA1
608818,3:193352432:C>T,NM_130837.2:c.844-775C>T,\N,\N,8/30,Unknown significance,\N,intron_variant,0.246,0.0008,1KG_AFR_AF,OPA1
608819,3:193352436:A>G,NM_130837.2:c.844-771A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,1.75,\N,\N,OPA1
608820,3:193352439:C>T,NM_130837.2:c.844-768C>T,\N,\N,8/30,Unknown significance,\N,intron_variant,0.164,\N,\N,OPA1
608821,3:193352440:G>A,NM_130837.2:c.844-767G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,1.055,0.0014,1KG_AMR_AF,OPA1
608822,3:193352448:C>A,NM_130837.2:c.844-759C>A,\N,\N,8/30,Unknown significance,\N,intron_variant,0.531,\N,\N,OPA1
608823,3:193352449:G>A,NM_130837.2:c.844-758G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,1.676,0.001,1KG_EUR_AF,OPA1
608824,3:193352480:A>C,NM_130837.2:c.844-727A>C,\N,\N,8/30,Unknown significance,\N,intron_variant,1.097,0.001,1KG_EAS_AF,OPA1
608825,3:193352488:C>T,NM_130837.2:c.844-719C>T,\N,\N,8/30,Unknown significance,\N,intron_variant,1.535,0.003,1KG_EAS_AF,OPA1
608826,3:193352498:A>G,NM_130837.2:c.844-709A>G,\N,\N,8/30,Benign,\N,intron_variant,5.158,0.1009,1KG_AMR_AF,OPA1
608827,3:193352518:A>T,NM_130837.2:c.844-689A>T,\N,\N,8/30,Benign,\N,intron_variant,2.583,0.0179,1KG_EAS_AF,OPA1
608828,3:193352536:A>G,NM_130837.2:c.844-671A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,2.317,\N,\N,OPA1
608829,3:193352538:G>A,NM_130837.2:c.844-669G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,3.099,\N,\N,OPA1
608830,3:193352550:A>C,NM_130837.2:c.844-657A>C,\N,\N,8/30,Unknown significance,\N,intron_variant,2.18,0.0008,1KG_AFR_AF,OPA1
608831,3:193352579:C>T,NM_130837.2:c.844-628C>T,\N,\N,8/30,Unknown significance,\N,intron_variant,1.9,\N,\N,OPA1
608832,3:193352618:G>C,NM_130837.2:c.844-589G>C,\N,\N,8/30,Unknown significance,\N,intron_variant,0.317,\N,\N,OPA1
608833,3:193352629:C>G,NM_130837.2:c.844-578C>G,\N,\N,8/30,Unknown significance,\N,intron_variant,1.16,\N,\N,OPA1
608834,3:193352637:C>G,NM_130837.2:c.844-570C>G,\N,\N,8/30,Unknown significance,\N,intron_variant,2.968,\N,\N,OPA1
608835,3:193352641:G>C,NM_130837.2:c.844-566G>C,\N,\N,8/30,Unknown significance,\N,intron_variant,0.22,0.001,1KG_EAS_AF,OPA1
608836,3:193352657:C>T,NM_130837.2:c.844-550C>T,\N,\N,8/30,Unknown significance,\N,intron_variant,4.84,\N,\N,OPA1
608837,3:193352709:G>A,NM_130837.2:c.844-498G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,0.236,0.0008,1KG_AFR_AF,OPA1
608838,3:193352744:G>A,NM_130837.2:c.844-463G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,3.829,\N,\N,OPA1
608839,3:193352765:T>G,NM_130837.2:c.844-442T>G,\N,\N,8/30,Unknown significance,\N,intron_variant,9.067,\N,\N,OPA1
608840,3:193352812:G>A,NM_130837.2:c.844-395G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,11.11,0.001,1KG_EAS_AF,OPA1
608841,3:193352840:C>T,NM_130837.2:c.844-367C>T,\N,\N,8/30,Unknown significance,\N,intron_variant,6.756,0.001,1KG_EUR_AF,OPA1
608842,3:193352842:C>T,NM_130837.2:c.844-365C>T,\N,\N,8/30,Unknown significance,\N,intron_variant,6.029,0.0008,1KG_AFR_AF,OPA1
608843,3:193352848:T>C,NM_130837.2:c.844-359T>C,\N,\N,8/30,Unknown significance,\N,intron_variant,0.138,0.0008,1KG_AFR_AF,OPA1
608844,3:193352855:A>G,NM_130837.2:c.844-352A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,2.603,0.001,1KG_EAS_AF,OPA1
608845,3:193352870:A>G,NM_130837.2:c.844-337A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,0.274,0.001,1KG_EAS_AF,OPA1
608846,3:193352872:A>G,NM_130837.2:c.844-335A>G,\N,\N,8/30,Benign,\N,intron_variant,0.687,0.0133,1KG_SAS_AF,OPA1
608847,3:193352889:T>A,NM_130837.2:c.844-318T>A,\N,\N,8/30,Unknown significance,\N,intron_variant,3.614,\N,\N,OPA1
608848,3:193352900:T>C,NM_130837.2:c.844-307T>C,\N,\N,8/30,Unknown significance,\N,intron_variant,1.511,0.0008,1KG_AFR_AF,OPA1
608849,3:193352910:A>G,NM_130837.2:c.844-297A>G,\N,\N,8/30,Benign,\N,intron_variant,0.928,0.007,1KG_EUR_AF,OPA1
608850,3:193352927:C>T,NM_130837.2:c.844-280C>T,\N,\N,8/30,Unknown significance,\N,intron_variant,2.45,0.001,1KG_SAS_AF,OPA1
608851,3:193352928:G>A,NM_130837.2:c.844-279G>A,\N,\N,8/30,Benign,\N,intron_variant,2.214,0.0367,1KG_EAS_AF,OPA1
608852,3:193353010:A>G,NM_130837.2:c.844-197A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,4.77,0.004,1KG_EAS_AF,OPA1
608853,3:193353014:T>A,NM_130837.2:c.844-193T>A,\N,\N,8/30,Unknown significance,\N,intron_variant,6.882,\N,\N,OPA1
608854,3:193353018:T>C,NM_130837.2:c.844-189T>C,\N,\N,8/30,Unknown significance,\N,intron_variant,2.813,\N,\N,OPA1
608855,3:193353072:G>A,NM_130837.2:c.844-135G>A,\N,\N,8/30,Benign,\N,intron_variant,0.842,0.584,1KG_AFR_AF,OPA1
608856,3:193353073:T>C,NM_130837.2:c.844-134T>C,\N,\N,8/30,Unknown significance,\N,intron_variant,1.263,0.003,1KG_EAS_AF,OPA1
608857,3:193353111:T>C,NM_130837.2:c.844-96T>C,\N,\N,8/30,Unknown significance,\N,intron_variant,3.298,\N,\N,OPA1
608858,3:193353117:T>C,NM_130837.2:c.844-90T>C,\N,\N,8/30,Unknown significance,\N,intron_variant,2.038,0.001,1KG_EUR_AF,OPA1
608859,3:193353125:T>C,NM_130837.2:c.844-82T>C,\N,\N,8/30,Unknown significance,\N,intron_variant,4.454,\N,\N,OPA1
608860,3:193353160:A>T,NM_130837.2:c.844-47A>T,\N,\N,8/30,Unknown significance,\N,intron_variant,1.512,0.000117233,EVS_EA_AF,OPA1
608861,3:193353166:C>T,NM_130837.2:c.844-41C>T,\N,\N,8/30,Unknown significance,\N,intron_variant,2.47,0.000061177,EXAC_SAS_AF,OPA1
608862,3:193353169:C>CT,NM_130837.2:c.844-34dup,\N,\N,8/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
608863,3:193353179:T>A,NM_130837.2:c.844-28T>A,\N,\N,8/30,Unknown significance,\N,intron_variant,7.914,0.00111857,EXAC_OTH_AF,OPA1
608864,3:193353180:A>G,NM_130837.2:c.844-27A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,5.636,0.0000151948,EXAC_NFE_AF,OPA1
608865,3:193353183:G>A,NM_130837.2:c.844-24G>A,\N,\N,8/30,Unknown significance,\N,intron_variant,3.782,0.0000609682,EXAC_SAS_AF,OPA1
608866,3:193353183:G>T,NM_130837.2:c.844-24G>T,\N,\N,8/30,Unknown significance,\N,intron_variant,1.297,0.0000151602,EXAC_NFE_AF,OPA1
608867,3:193353185:T>C,NM_130837.2:c.844-22T>C,\N,\N,8/30,Unknown significance,\N,intron_variant,4.469,0.000174064,EXAC_AMR_AF,OPA1
608868,3:193353186:A>G,NM_130837.2:c.844-21A>G,\N,\N,8/30,Unknown significance,\N,intron_variant,5.719,0.000117454,EXAC_EAS_AF,OPA1
608869,3:193353189:CTTA>C,NM_130837.2:c.844-12_844-10del,\N,\N,8/30,Unknown significance,\N,intron_variant,12.74,0.0000869112,EXAC_AMR_AF,OPA1
608870,3:193353196:T>G,NM_130837.2:c.844-11T>G,\N,\N,8/30,Unknown significance,\N,intron_variant,11.66,0.000151286,EXAC_FIN_AF,OPA1
608871,3:193353199:T>G,NM_130837.2:c.844-8T>G,\N,\N,8/30,Unknown significance,\N,splice_region_variant&intron_variant,11.27,0.000242866,EXAC_SAS_AF,OPA1
608872,3:193353203:G>A,NM_130837.2:c.844-4G>A,\N,\N,8/30,Unknown significance,\N,splice_region_variant&intron_variant,10.35,0.001,1KG_SAS_AF,OPA1
608873,3:193353214:A>G,NM_130837.2:c.851A>G,NP_570850.2:p.Tyr284Cys,9/31,\N,Unknown significance,\N,missense_variant,29.4,0.000100381,EXAC_AFR_AF,OPA1
608874,3:193353214:A>T,NM_015560.2:c.686A>T,NP_056375.2:p.Tyr229Phe,7/29,\N,Unknown significance,\N,missense_variant,24.6,0.000115794,EXAC_EAS_AF,OPA1
608875,3:193353215:T>G,NM_130837.2:c.852T>G,NP_570850.2:p.Tyr284Ter,9/31,\N,Pathogenic,\N,stop_gained,36,\N,\N,OPA1
608876,3:193353215:T>A,NM_130837.2:c.852T>A,NP_570850.2:p.Tyr284Ter,9/31,\N,Pathogenic,Optic atrophy 1,stop_gained,36,\N,\N,OPA1
608877,3:193353217:A>G,NM_130837.2:c.854A>G,NP_570850.2:p.Gln285Arg,9/31,\N,Pathogenic,Optic atrophy| ataxia & spasticity,missense_variant,28.8,\N,\N,OPA1
608878,3:193353218:G>T,NM_130837.2:c.855G>T,NP_570850.2:p.Gln285His,9/31,\N,Unknown significance,\N,missense_variant,26.2,0.000075127,EXAC_NFE_AF,OPA1
608879,3:193353231:C>T,NM_130837.2:c.868C>T,NP_570850.2:p.Arg290Ter,9/31,\N,Pathogenic,Optic atrophy,stop_gained,40,0.0000606061,EXAC_SAS_AF,OPA1
608880,3:193353232:G>A,NM_130837.2:c.869G>A,NP_570850.2:p.Arg290Gln,9/31,\N,Unknown significance,\N,missense_variant,23.9,0.000198965,EXAC_AFR_AF,OPA1
608881,3:193353242:G>A,NM_130837.2:c.879G>A,NP_570850.2:p.Lys293=,9/31,\N,Unknown significance,\N,synonymous_variant,14.09,\N,\N,OPA1
608882,3:193353248:C>G,NM_130837.2:c.885C>G,NP_570850.2:p.Asn295Lys,9/31,\N,Unknown significance,\N,missense_variant,29.3,0.0000150096,EXAC_NFE_AF,OPA1
608883,3:193353252:G>T,NM_130837.2:c.889G>T,NP_570850.2:p.Glu297Ter,9/31,\N,Pathogenic,Optic atrophy 1,stop_gained,43,\N,\N,OPA1
608884,3:193353256:T>A,NM_130837.2:c.893T>A,NP_570850.2:p.Leu298Ter,9/31,\N,Pathogenic,Optic atrophy 1,stop_gained,37,\N,\N,OPA1
608885,3:193353261:A>T,NM_130837.2:c.898A>T,NP_570850.2:p.Lys300Ter,9/31,\N,Pathogenic,Optic atrophy 1,stop_gained,40,\N,\N,OPA1
608886,3:193353284:C>T,NM_130837.2:c.921C>T,NP_570850.2:p.Asp307=,9/31,\N,Unknown significance,\N,synonymous_variant,15.16,0.00158874,EVS_AA_AF,OPA1
608887,3:193353289:G>C,NM_130837.2:c.926G>C,NP_570850.2:p.Gly309Ala,9/31,\N,Unknown significance,\N,missense_variant,14.78,0.000121212,EXAC_SAS_AF,OPA1
608888,3:193353299:T>C,NM_130837.2:c.936T>C,NP_570850.2:p.His312=,9/31,\N,Unknown significance,\N,synonymous_variant,7.145,\N,\N,OPA1
608889,3:193353316:T>G,NM_130837.2:c.948+5T>G,\N,\N,9/30,Unknown significance,\N,splice_region_variant&intron_variant,11.45,0.000116387,EVS_EA_AF,OPA1
608890,3:193353321:G>A,NM_130837.2:c.948+10G>A,\N,\N,9/30,Unknown significance,\N,intron_variant,14.51,\N,\N,OPA1
608891,3:193353334:A>G,NM_130837.2:c.948+23A>G,\N,\N,9/30,Unknown significance,\N,intron_variant,12.23,0.0000869716,EXAC_AMR_AF,OPA1
608892,3:193353341:A>G,NM_130837.2:c.948+30A>G,\N,\N,9/30,Unknown significance,\N,intron_variant,9.642,\N,\N,OPA1
608893,3:193353347:T>G,NM_130837.2:c.948+36T>G,\N,\N,9/30,Unknown significance,\N,intron_variant,6.155,0.0000302673,EXAC_NFE_AF,OPA1
608894,3:193353348:A>T,NM_130837.2:c.948+37A>T,\N,\N,9/30,Unknown significance,\N,intron_variant,0.676,0.0000607829,EXAC_SAS_AF,OPA1
608895,3:193353350:C>T,NM_130837.2:c.948+39C>T,\N,\N,9/30,Unknown significance,\N,intron_variant,0.36,0.0000454738,EXAC_NFE_AF,OPA1
608896,3:193353351:G>A,NM_130837.2:c.948+40G>A,\N,\N,9/30,Unknown significance,\N,intron_variant,1.426,0.000118568,EXAC_EAS_AF,OPA1
608897,3:193353355:A>G,NM_130837.2:c.948+44A>G,\N,\N,9/30,Unknown significance,\N,intron_variant,3.623,0.000116442,EVS_EA_AF,OPA1
608898,3:193353357:C>T,NM_130837.2:c.948+46C>T,\N,\N,9/30,Unknown significance,\N,intron_variant,3.383,0.0000456704,EXAC_NFE_AF,OPA1
608899,3:193353358:G>A,NM_130837.2:c.948+47G>A,\N,\N,9/30,Unknown significance,\N,intron_variant,1.045,0.003,1KG_EUR_AF,OPA1
608900,3:193353378:A>G,NM_130837.2:c.948+67A>G,\N,\N,9/30,Unknown significance,\N,intron_variant,4.725,\N,\N,OPA1
608901,3:193353390:G>T,NM_130837.2:c.948+79G>T,\N,\N,9/30,Unknown significance,\N,intron_variant,0.585,0.0029,1KG_AMR_AF,OPA1
608902,3:193353391:C>T,NM_130837.2:c.948+80C>T,\N,\N,9/30,Unknown significance,\N,intron_variant,2.371,0.0008,1KG_AFR_AF,OPA1
608903,3:193353424:C>G,NM_130837.2:c.948+113C>G,\N,\N,9/30,Unknown significance,\N,intron_variant,0.388,0.001,1KG_EAS_AF,OPA1
608904,3:193353454:T>G,NM_130837.2:c.948+143T>G,\N,\N,9/30,Unknown significance,\N,intron_variant,10.66,\N,\N,OPA1
608905,3:193353469:T>C,NM_130837.2:c.948+158T>C,\N,\N,9/30,Unknown significance,\N,intron_variant,1.418,0.001,1KG_EAS_AF,OPA1
608906,3:193353473:A>G,NM_130837.2:c.948+162A>G,\N,\N,9/30,Unknown significance,\N,intron_variant,2.67,\N,\N,OPA1
608907,3:193353480:G>T,NM_130837.2:c.948+169G>T,\N,\N,9/30,Unknown significance,\N,intron_variant,0.27,\N,\N,OPA1
608908,3:193353487:C>T,NM_130837.2:c.948+176C>T,\N,\N,9/30,Unknown significance,\N,intron_variant,4.718,0.001,1KG_EAS_AF,OPA1
608909,3:193353508:T>C,NM_130837.2:c.948+197T>C,\N,\N,9/30,Unknown significance,\N,intron_variant,0.871,\N,\N,OPA1
608910,3:193353552:C>T,NM_130837.2:c.948+241C>T,\N,\N,9/30,Unknown significance,\N,intron_variant,13.49,\N,\N,OPA1
608911,3:193353572:T>C,NM_130837.2:c.948+261T>C,\N,\N,9/30,Unknown significance,\N,intron_variant,1.333,\N,\N,OPA1
608912,3:193353615:A>G,NM_130837.2:c.948+304A>G,\N,\N,9/30,Unknown significance,\N,intron_variant,2.015,0.0008,1KG_AFR_AF,OPA1
608913,3:193353637:G>A,NM_130837.2:c.948+326G>A,\N,\N,9/30,Unknown significance,\N,intron_variant,4.994,\N,\N,OPA1
608914,3:193353663:G>A,NM_130837.2:c.948+352G>A,\N,\N,9/30,Unknown significance,\N,intron_variant,1.891,\N,\N,OPA1
608915,3:193353673:T>C,NM_130837.2:c.948+362T>C,\N,\N,9/30,Unknown significance,\N,intron_variant,8.105,0.001,1KG_SAS_AF,OPA1
608916,3:193353675:T>C,NM_130837.2:c.948+364T>C,\N,\N,9/30,Unknown significance,\N,intron_variant,9.493,\N,\N,OPA1
608917,3:193353700:C>G,NM_130837.2:c.948+389C>G,\N,\N,9/30,Unknown significance,\N,intron_variant,12.82,\N,\N,OPA1
608918,3:193353726:T>TC,NM_130837.2:c.948+415_948+416insC,\N,\N,9/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
608919,3:193353751:C>T,NM_130837.2:c.948+440C>T,\N,\N,9/30,Unknown significance,\N,intron_variant,3.098,\N,\N,OPA1
608920,3:193353777:T>C,NM_130837.2:c.948+466T>C,\N,\N,9/30,Benign,\N,intron_variant,4.456,0.1051,1KG_AFR_AF,OPA1
608921,3:193353807:G>T,NM_130837.2:c.948+496G>T,\N,\N,9/30,Unknown significance,\N,intron_variant,11.72,0.001,1KG_SAS_AF,OPA1
608922,3:193353829:C>T,NM_130837.2:c.948+518C>T,\N,\N,9/30,Unknown significance,\N,intron_variant,2.599,\N,\N,OPA1
608923,3:193353906:A>G,NM_130837.2:c.948+595A>G,\N,\N,9/30,Unknown significance,\N,intron_variant,3.998,0.0015,1KG_AFR_AF,OPA1
608924,3:193353927:G>A,NM_130837.2:c.948+616G>A,\N,\N,9/30,Unknown significance,\N,intron_variant,4.5,0.0014,1KG_AMR_AF,OPA1
608925,3:193353940:A>G,NM_130837.2:c.948+629A>G,\N,\N,9/30,Unknown significance,\N,intron_variant,13.44,0.0008,1KG_AFR_AF,OPA1
608926,3:193353955:G>A,NM_130837.2:c.948+644G>A,\N,\N,9/30,Benign,\N,intron_variant,14.11,0.584,1KG_AFR_AF,OPA1
608927,3:193353964:G>A,NM_130837.2:c.948+653G>A,\N,\N,9/30,Unknown significance,\N,intron_variant,12.45,0.001,1KG_SAS_AF,OPA1
608928,3:193353966:A>T,NM_130837.2:c.948+655A>T,\N,\N,9/30,Unknown significance,\N,intron_variant,10.74,\N,\N,OPA1
608929,3:193353972:G>T,NM_130837.2:c.948+661G>T,\N,\N,9/30,Unknown significance,\N,intron_variant,0.349,0.0014,1KG_AMR_AF,OPA1
608930,3:193353975:C>G,NM_130837.2:c.948+664C>G,\N,\N,9/30,Unknown significance,\N,intron_variant,0.232,0.002,1KG_EUR_AF,OPA1
608931,3:193354055:A>T,NM_130837.2:c.948+744A>T,\N,\N,9/30,Unknown significance,\N,intron_variant,0.781,\N,\N,OPA1
608932,3:193354074:A>G,NM_130837.2:c.948+763A>G,\N,\N,9/30,Benign,\N,intron_variant,2.58,0.0053,1KG_AFR_AF,OPA1
608933,3:193354087:A>G,NM_130837.2:c.948+776A>G,\N,\N,9/30,Unknown significance,\N,intron_variant,6.028,\N,\N,OPA1
608934,3:193354092:T>C,NM_130837.2:c.948+781T>C,\N,\N,9/30,Benign,\N,intron_variant,6.595,0.0061,1KG_SAS_AF,OPA1
608935,3:193354110:A>T,NM_130837.2:c.948+799A>T,\N,\N,9/30,Unknown significance,\N,intron_variant,0.974,0.0008,1KG_AFR_AF,OPA1
608936,3:193354160:G>A,NM_130837.2:c.949-824G>A,\N,\N,9/30,Unknown significance,\N,intron_variant,2.299,0.0029,1KG_AMR_AF,OPA1
608937,3:193354176:G>T,NM_130837.2:c.949-808G>T,\N,\N,9/30,Unknown significance,\N,intron_variant,11.19,\N,\N,OPA1
608938,3:193354179:T>G,NM_130837.2:c.949-805T>G,\N,\N,9/30,Unknown significance,\N,intron_variant,13.47,\N,\N,OPA1
608939,3:193354180:A>T,NM_130837.2:c.949-804A>T,\N,\N,9/30,Unknown significance,\N,intron_variant,11.81,\N,\N,OPA1
608940,3:193354192:G>T,NM_130837.2:c.949-792G>T,\N,\N,9/30,Unknown significance,\N,intron_variant,0.628,\N,\N,OPA1
608941,3:193354243:A>C,NM_130837.2:c.949-741A>C,\N,\N,9/30,Unknown significance,\N,intron_variant,3.857,0.0008,1KG_AFR_AF,OPA1
608942,3:193354305:A>G,NM_130837.2:c.949-679A>G,\N,\N,9/30,Benign,\N,intron_variant,6.752,0.0058,1KG_AMR_AF,OPA1
608943,3:193354356:A>T,NM_130837.2:c.949-628A>T,\N,\N,9/30,Benign,\N,intron_variant,2.619,0.0265,1KG_AFR_AF,OPA1
608944,3:193354396:G>A,NM_130837.2:c.949-588G>A,\N,\N,9/30,Unknown significance,\N,intron_variant,6.358,\N,\N,OPA1
608945,3:193354397:G>C,NM_130837.2:c.949-587G>C,\N,\N,9/30,Unknown significance,\N,intron_variant,1.462,\N,\N,OPA1
608946,3:193354406:T>C,NM_130837.2:c.949-578T>C,\N,\N,9/30,Unknown significance,\N,intron_variant,5.708,\N,\N,OPA1
608947,3:193354432:G>A,NM_130837.2:c.949-552G>A,\N,\N,9/30,Unknown significance,\N,intron_variant,1.922,\N,\N,OPA1
608948,3:193354457:ACT>A,NM_130837.2:c.949-525_949-524del,\N,\N,9/30,Unknown significance,\N,intron_variant,2.652,0.0041,1KG_SAS_AF,OPA1
608949,3:193354487:G>C,NM_130837.2:c.949-497G>C,\N,\N,9/30,Unknown significance,\N,intron_variant,1.176,0.001,1KG_EUR_AF,OPA1
608950,3:193354508:G>A,NM_130837.2:c.949-476G>A,\N,\N,9/30,Unknown significance,\N,intron_variant,4.976,\N,\N,OPA1
608951,3:193354542:G>A,NM_130837.2:c.949-442G>A,\N,\N,9/30,Unknown significance,\N,intron_variant,2.927,\N,\N,OPA1
608952,3:193354555:A>T,NM_130837.2:c.949-429A>T,\N,\N,9/30,Unknown significance,\N,intron_variant,3.279,0.001,1KG_EAS_AF,OPA1
608953,3:193354564:C>G,NM_130837.2:c.949-420C>G,\N,\N,9/30,Benign,\N,intron_variant,3.723,0.0388,1KG_EUR_AF,OPA1
608954,3:193354598:A>G,NM_130837.2:c.949-386A>G,\N,\N,9/30,Unknown significance,\N,intron_variant,2.361,0.0038,1KG_AFR_AF,OPA1
608955,3:193354619:A>G,NM_130837.2:c.949-365A>G,\N,\N,9/30,Unknown significance,\N,intron_variant,9.905,0.0031,1KG_SAS_AF,OPA1
608956,3:193354625:A>G,NM_130837.2:c.949-359A>G,\N,\N,9/30,Unknown significance,\N,intron_variant,8.604,0.001,1KG_EUR_AF,OPA1
608957,3:193354643:CT>C,NM_130837.2:c.949-333del,\N,\N,9/30,Benign,\N,intron_variant,2.418,0.5862,1KG_AFR_AF,OPA1
608958,3:193354680:G>T,NM_130837.2:c.949-304G>T,\N,\N,9/30,Unknown significance,\N,intron_variant,6.302,0.003,1KG_EUR_AF,OPA1
608959,3:193354761:A>G,NM_130837.2:c.949-223A>G,\N,\N,9/30,Unknown significance,\N,intron_variant,3.606,0.0014,1KG_AMR_AF,OPA1
608960,3:193354765:T>C,NM_130837.2:c.949-219T>C,\N,\N,9/30,Benign,\N,intron_variant,2.971,0.006,1KG_EAS_AF,OPA1
608961,3:193354777:G>A,NM_130837.2:c.949-207G>A,\N,\N,9/30,Unknown significance,\N,intron_variant,0.26,\N,\N,OPA1
608962,3:193354821:G>A,NM_130837.2:c.949-163G>A,\N,\N,9/30,Unknown significance,\N,intron_variant,0.716,0.0008,1KG_AFR_AF,OPA1
608963,3:193354834:C>T,NM_130837.2:c.949-150C>T,\N,\N,9/30,Unknown significance,\N,intron_variant,1.939,\N,\N,OPA1
608964,3:193354836:A>T,NM_130837.2:c.949-148A>T,\N,\N,9/30,Unknown significance,\N,intron_variant,1.452,0.001,1KG_SAS_AF,OPA1
608965,3:193354861:G>T,NM_130837.2:c.949-123G>T,\N,\N,9/30,Unknown significance,\N,intron_variant,1.488,\N,\N,OPA1
608966,3:193354871:CAAT>C,NM_130837.2:c.949-112_949-110del,\N,\N,9/30,Unknown significance,\N,intron_variant,7.22,0.003,1KG_AFR_AF,OPA1
608967,3:193354924:T>C,NM_130837.2:c.949-60T>C,\N,\N,9/30,Unknown significance,\N,intron_variant,1.208,\N,\N,OPA1
608968,3:193354927:T>A,NM_130837.2:c.949-57T>A,\N,\N,9/30,Unknown significance,\N,intron_variant,2.93,\N,\N,OPA1
608969,3:193354933:TTTTTC>T,NM_130837.2:c.949-47_949-43del,\N,\N,9/30,Unknown significance,\N,intron_variant,2.652,0.0000288684,EXAC_NFE_AF,OPA1
608970,3:193354934:T>G,NM_130837.2:c.949-50T>G,\N,\N,9/30,Unknown significance,\N,intron_variant,2.635,0.0000291002,EXAC_NFE_AF,OPA1
608971,3:193354937:TCTTTA>T,NM_130837.2:c.949-42_949-38del,\N,\N,9/30,Unknown significance,\N,intron_variant,4.624,0.000348918,EXAC_FIN_AF,OPA1
608972,3:193354948:A>G,NM_130837.2:c.949-36A>G,\N,\N,9/30,Unknown significance,\N,intron_variant,3.212,0.0000283736,EXAC_NFE_AF,OPA1
608973,3:193354951:G>C,NM_130837.2:c.949-33G>C,\N,\N,9/30,Unknown significance,\N,intron_variant,1.371,0.00084246,EXAC_EAS_AF,OPA1
608974,3:193354953:TTTATA>T,NM_130837.2:c.949-25_949-21del,\N,\N,9/30,Benign,\N,intron_variant,11.29,0.0133,1KG_SAS_AF,OPA1
608975,3:193354956:A>G,NM_130837.2:c.949-28A>G,\N,\N,9/30,Unknown significance,\N,intron_variant,6.999,0.0000806842,EXAC_SAS_AF,OPA1
608976,3:193354958:A>T,NM_130837.2:c.949-26A>T,\N,\N,9/30,Unknown significance,\N,intron_variant,6.063,0.00002602,EXAC_NFE_AF,OPA1
608977,3:193354961:A>G,NM_130837.2:c.949-23A>G,\N,\N,9/30,Unknown significance,\N,intron_variant,8.413,0.0000245773,EXAC_NFE_AF,OPA1
608978,3:193354962:T>C,NM_130837.2:c.949-22T>C,\N,\N,9/30,Unknown significance,\N,intron_variant,3.766,\N,\N,OPA1
608979,3:193354963:A>C,NM_130837.2:c.949-21A>C,\N,\N,9/30,Unknown significance,\N,intron_variant,0.396,\N,\N,OPA1
608980,3:193354971:A>AAT,NM_130837.2:c.949-12_949-11insTA,\N,\N,9/30,Unknown significance,\N,intron_variant,0.371,0.00267606,EXAC_AFR_AF,OPA1
608981,3:193354973:A>C,NM_130837.2:c.949-11A>C,\N,\N,9/30,Unknown significance,\N,intron_variant,2.767,0.00420561,EVS_AA_AF,OPA1
608982,3:193354980:A>G,NM_130837.2:c.949-4A>G,\N,\N,9/30,Unknown significance,\N,splice_region_variant&intron_variant,9.767,0.000123946,EXAC_EAS_AF,OPA1
608983,3:193354982:A>C,NM_130837.2:c.949-2A>C,\N,\N,9/30,Pathogenic,Optic atrophy,splice_acceptor_variant,23.8,\N,\N,OPA1
608984,3:193354982:A>G,NM_130837.2:c.949-2A>G,\N,\N,9/30,Pathogenic,Optic atrophy,splice_acceptor_variant,24.1,\N,\N,OPA1
608985,3:193354982:A>T,NM_130837.2:c.949-2A>T,\N,\N,9/30,Pathogenic,Optic atrophy 1,splice_acceptor_variant,23.8,\N,\N,OPA1
608986,3:193354983:G>A,NM_130837.2:c.949-1G>A,\N,\N,9/30,Pathogenic,Optic atrophy 1,splice_acceptor_variant,25.6,\N,\N,OPA1
608987,3:193354983:G>T,NM_130837.2:c.949-1G>T,\N,\N,9/30,Pathogenic,Optic atrophy 1,splice_acceptor_variant,25,\N,\N,OPA1
608988,3:193354989:TTTGA>T,NM_130837.2:c.959_962del,NP_570850.2:p.Ile320ThrfsTer42,10/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,35,\N,\N,OPA1
608989,3:193354995:TGACA>T,NM_130837.2:c.961_964del,NP_570850.2:p.Asp321CysfsTer41,10/31,\N,Pathogenic,Optic neuropathy,frameshift_variant,35,\N,\N,OPA1
608990,3:193355003:A>G,NM_130837.2:c.968A>G,NP_570850.2:p.Tyr323Cys,10/31,\N,Pathogenic,Optic atrophy,missense_variant,29.4,\N,\N,OPA1
608991,3:193355008:G>A,NM_130837.2:c.973G>A,NP_570850.2:p.Glu325Lys,10/31,\N,Pathogenic,Optic atrophy 1,missense_variant,33,\N,\N,OPA1
608992,3:193355012:T>C,NM_015560.2:c.812T>C,NP_056375.2:p.Val271Ala,8/29,\N,Unknown significance,\N,missense_variant,24.2,0.0000607607,EXAC_SAS_AF,OPA1
608993,3:193355015:T>C,NM_130837.2:c.980T>C,NP_570850.2:p.Leu327Pro,10/31,\N,Pathogenic,Optic atrophy 1,missense_variant,27.7,\N,\N,OPA1
608994,3:193355018:A>C,NM_130837.2:c.983A>C,NP_570850.2:p.Asp328Ala,10/31,\N,Pathogenic,Optic atrophy 1,missense_variant,28.3,\N,\N,OPA1
608995,3:193355025:C>G,NM_130837.2:c.990C>G,NP_570850.2:p.Leu330=,10/31,\N,Unknown significance,\N,synonymous_variant,13.92,0.000182127,EXAC_SAS_AF,OPA1
608996,3:193355025:C>T,NM_130837.2:c.990C>T,NP_570850.2:p.Leu330=,10/31,\N,Unknown significance,\N,synonymous_variant,15.45,0.000097561,EXAC_AFR_AF,OPA1
608997,3:193355038:G>A,NM_130837.2:c.1003G>A,NP_570850.2:p.Ala335Thr,10/31,\N,Unknown significance,\N,missense_variant,22.1,0.000116279,EVS_EA_AF,OPA1
608998,3:193355041:A>C,NM_130837.2:c.1006A>C,NP_570850.2:p.Ser336Arg,10/31,\N,Unknown significance,\N,missense_variant,23.6,0.0000865801,EXAC_AMR_AF,OPA1
608999,3:193355046:T>C,NM_130837.2:c.1011T>C,NP_570850.2:p.Tyr337=,10/31,\N,Unknown significance,\N,synonymous_variant,0.986,\N,\N,OPA1
609000,3:193355050:A>G,NM_015560.2:c.850A>G,NP_056375.2:p.Thr284Ala,8/29,\N,Unknown significance,\N,missense_variant,18.52,\N,\N,OPA1
609001,3:193355051:C>T,NM_015560.2:c.851C>T,NP_056375.2:p.Thr284Met,8/29,\N,Unknown significance,\N,missense_variant,25.9,0.000116279,EVS_EA_AF,OPA1
609002,3:193355052:G>A,NM_130837.2:c.1017G>A,NP_570850.2:p.Thr339=,10/31,\N,Unknown significance,\N,synonymous_variant,11.28,0.000115929,EXAC_EAS_AF,OPA1
609003,3:193355054:A>C,NM_130837.2:c.1019A>C,NP_570850.2:p.Gln340Pro,10/31,\N,Unknown significance,\N,missense_variant,23.9,0.000116279,EVS_EA_AF,OPA1
609004,3:193355066:C>T,NM_130837.2:c.1031C>T,NP_570850.2:p.Pro344Leu,10/31,\N,Pathogenic,\N,missense_variant,28,\N,\N,OPA1
609005,3:193355068:C>T,NM_130837.2:c.1033C>T,NP_570850.2:p.Arg345Trp,10/31,\N,Pathogenic,Optic atrophy 1,missense_variant&splice_region_variant,29.4,0.0000300309,EXAC_NFE_AF,OPA1
609006,3:193355069:G>A,NM_130837.2:c.1034G>A,NP_570850.2:p.Arg345Gln,10/31,\N,Pathogenic,Optic atrophy 1,missense_variant&splice_region_variant,30,\N,\N,OPA1
609007,3:193355070:G>A,NM_130837.2:c.1035G>A,NP_570850.2:p.Arg345=,10/31,\N,Unknown significance,\N,splice_region_variant&synonymous_variant,8.945,\N,\N,OPA1
609008,3:193355071:G>A,NM_130837.2:c.1035+1G>A,\N,\N,10/30,Pathogenic,Optic atrophy,splice_donor_variant,24.1,\N,\N,OPA1
609009,3:193355071:G>T,NM_130837.2:c.1035+1G>T,\N,\N,10/30,Pathogenic,Optic atrophy 1,splice_donor_variant,23.8,\N,\N,OPA1
609010,3:193355074:T>C,NM_130837.2:c.1035+4T>C,\N,\N,10/30,Benign,\N,splice_region_variant&intron_variant,0.116,0.9871,1KG_AFR_AF,OPA1
609011,3:193355075:G>A,NM_130837.2:c.1035+5G>A,\N,\N,10/30,Pathogenic,Optic atrophy 1,splice_region_variant&intron_variant,5.852,0.0000149948,EXAC_NFE_AF,OPA1
609012,3:193355090:T>C,NM_130837.2:c.1035+20T>C,\N,\N,10/30,Unknown significance,\N,intron_variant,15.74,0.000116279,EVS_EA_AF,OPA1
609013,3:193355094:C>CT,NM_130837.2:c.1035+26dup,\N,\N,10/30,Unknown significance,\N,intron_variant,16.91,0.000014997,EXAC_NFE_AF,OPA1
609014,3:193355100:A>G,NM_130837.2:c.1035+30A>G,\N,\N,10/30,Unknown significance,\N,intron_variant,13.89,0.000115768,EXAC_EAS_AF,OPA1
609015,3:193355102:T>C,NM_130837.2:c.1035+32T>C,\N,\N,10/30,Benign,\N,intron_variant,14.98,0.5291,EXAC_FIN_AF,OPA1
609016,3:193355106:C>T,NM_130837.2:c.1035+36C>T,\N,\N,10/30,Unknown significance,\N,intron_variant,16.83,0.000116279,EVS_EA_AF,OPA1
609017,3:193355107:A>C,NM_130837.2:c.1035+37A>C,\N,\N,10/30,Benign,\N,intron_variant,13.92,0.1051,1KG_AFR_AF,OPA1
609018,3:193355109:A>G,NM_130837.2:c.1035+39A>G,\N,\N,10/30,Unknown significance,\N,intron_variant,6.874,0.0000606355,EXAC_SAS_AF,OPA1
609019,3:193355111:AAAG>A,NM_130837.2:c.1035+45_1035+47del,\N,\N,10/30,Unknown significance,\N,intron_variant,0.847,0.0001213,EXAC_SAS_AF,OPA1
609020,3:193355115:A>C,NM_130837.2:c.1035+45A>C,\N,\N,10/30,Unknown significance,\N,intron_variant,0.033,0.0000865801,EXAC_AMR_AF,OPA1
609021,3:193355140:T>C,NM_130837.2:c.1035+70T>C,\N,\N,10/30,Unknown significance,\N,intron_variant,3.168,\N,\N,OPA1
609022,3:193355225:G>A,NM_130837.2:c.1035+155G>A,\N,\N,10/30,Unknown significance,\N,intron_variant,2.256,0.001,1KG_SAS_AF,OPA1
609023,3:193355312:T>G,NM_130837.2:c.1035+242T>G,\N,\N,10/30,Unknown significance,\N,intron_variant,3.316,\N,\N,OPA1
609024,3:193355337:A>T,NM_130837.2:c.1035+267A>T,\N,\N,10/30,Unknown significance,\N,intron_variant,0.68,\N,\N,OPA1
609025,3:193355394:G>A,NM_130837.2:c.1035+324G>A,\N,\N,10/30,Benign,\N,intron_variant,1.52,0.0234,1KG_AFR_AF,OPA1
609026,3:193355431:A>G,NM_130837.2:c.1036-310A>G,\N,\N,10/30,Unknown significance,\N,intron_variant,10.96,\N,\N,OPA1
609027,3:193355455:G>T,NM_130837.2:c.1036-286G>T,\N,\N,10/30,Benign,\N,intron_variant,0.863,0.0179,1KG_EAS_AF,OPA1
609028,3:193355478:G>C,NM_130837.2:c.1036-263G>C,\N,\N,10/30,Unknown significance,\N,intron_variant,0.756,\N,\N,OPA1
609029,3:193355492:T>G,NM_130837.2:c.1036-249T>G,\N,\N,10/30,Unknown significance,\N,intron_variant,6.202,\N,\N,OPA1
609030,3:193355536:A>AC,NM_130837.2:c.1036-205_1036-204insC,\N,\N,10/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
609031,3:193355556:T>C,NM_130837.2:c.1036-185T>C,\N,\N,10/30,Unknown significance,\N,intron_variant,3.862,\N,\N,OPA1
609032,3:193355569:A>G,NM_130837.2:c.1036-172A>G,\N,\N,10/30,Unknown significance,\N,intron_variant,2.293,0.002,1KG_SAS_AF,OPA1
609033,3:193355576:A>G,NM_130837.2:c.1036-165A>G,\N,\N,10/30,Unknown significance,\N,intron_variant,1.31,0.0008,1KG_AFR_AF,OPA1
609034,3:193355593:A>C,NM_130837.2:c.1036-148A>C,\N,\N,10/30,Unknown significance,\N,intron_variant,1.56,\N,\N,OPA1
609035,3:193355600:A>T,NM_130837.2:c.1036-141A>T,\N,\N,10/30,Unknown significance,\N,intron_variant,2.931,0.0014,1KG_AMR_AF,OPA1
609036,3:193355600:AT>A,NM_130837.2:c.1036-134del,\N,\N,10/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
609037,3:193355606:T>G,NM_130837.2:c.1036-135T>G,\N,\N,10/30,Unknown significance,\N,intron_variant,6.338,0.001,1KG_SAS_AF,OPA1
609038,3:193355609:C>T,NM_130837.2:c.1036-132C>T,\N,\N,10/30,Unknown significance,\N,intron_variant,1.06,\N,\N,OPA1
609039,3:193355634:G>C,NM_130837.2:c.1036-107G>C,\N,\N,10/30,Unknown significance,\N,intron_variant,0.43,\N,\N,OPA1
609040,3:193355652:T>TA,NM_130837.2:c.1036-83dup,\N,\N,10/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
609041,3:193355678:T>C,NM_130837.2:c.1036-63T>C,\N,\N,10/30,Unknown significance,\N,intron_variant,4.795,\N,\N,OPA1
609042,3:193355691:T>C,NM_130837.2:c.1036-50T>C,\N,\N,10/30,Unknown significance,\N,intron_variant,1.701,\N,\N,OPA1
609043,3:193355703:A>G,NM_130837.2:c.1036-38A>G,\N,\N,10/30,Unknown significance,\N,intron_variant,4.666,0.0000702741,EXAC_SAS_AF,OPA1
609044,3:193355704:G>A,NM_130837.2:c.1036-37G>A,\N,\N,10/30,Unknown significance,\N,intron_variant,2.734,\N,\N,OPA1
609045,3:193355710:T>C,NM_130837.2:c.1036-31T>C,\N,\N,10/30,Unknown significance,\N,intron_variant,4.255,0.0000345304,EXAC_NFE_AF,OPA1
609046,3:193355715:A>G,NM_130837.2:c.1036-26A>G,\N,\N,10/30,Unknown significance,\N,intron_variant,2.139,0.000137627,EXAC_SAS_AF,OPA1
609047,3:193355717:A>C,NM_130837.2:c.1036-24A>C,\N,\N,10/30,Unknown significance,\N,intron_variant,2.995,\N,\N,OPA1
609048,3:193355732:T>C,NM_130837.2:c.1036-9T>C,\N,\N,10/30,Unknown significance,\N,intron_variant,11.01,0.002,1KG_SAS_AF,OPA1
609049,3:193355733:G>T,NM_130837.2:c.1036-8G>T,\N,\N,10/30,Unknown significance,\N,splice_region_variant&intron_variant,8.084,0.000226963,EVS_AA_AF,OPA1
609050,3:193355738:A>G,NM_130837.2:c.1036-3A>G,\N,\N,10/30,Unknown significance,\N,splice_region_variant&intron_variant,10.81,\N,\N,OPA1
609051,3:193355740:G>A,NM_130837.2:c.1036-1G>A,\N,\N,10/30,Pathogenic,Optic atrophy 1,splice_acceptor_variant,26.1,\N,\N,OPA1
609052,3:193355740:G>T,NM_130837.2:c.1036-1G>T,\N,\N,10/30,Pathogenic,Optic atrophy 1,splice_acceptor_variant,25.2,\N,\N,OPA1
609053,3:193355740:GGTT>G,NM_130837.2:c.1041_1043del,NP_570850.2:p.Val349del,11/31,\N,Pathogenic,Optic atrophy & spastic paraplegia,inframe_deletion&splice_region_variant,20.9,\N,\N,OPA1
609054,3:193355743:TGTTGTG>T,NM_130837.2:c.1043_1048del,NP_570850.2:p.Val348_Val349del,11/31,\N,Pathogenic,Optic atrophy 1,inframe_deletion,21.9,\N,\N,OPA1
609055,3:193355749:G>A,NM_130837.2:c.1044G>A,NP_570850.2:p.Val348=,11/31,\N,Unknown significance,\N,synonymous_variant,9.241,0.0000968429,EXAC_AFR_AF,OPA1
609056,3:193355750:G>T,NM_130837.2:c.1045G>T,NP_570850.2:p.Val349Phe,11/31,\N,Likely pathogenic,\N,missense_variant,29.7,\N,\N,OPA1
609057,3:193355759:C>T,NM_130837.2:c.1054C>T,NP_570850.2:p.Gln352Ter,11/31,\N,Pathogenic,Optic atrophy,stop_gained,39,\N,\N,OPA1
609058,3:193355763:G>A,NM_130837.2:c.1058G>A,NP_570850.2:p.Ser353Asn,11/31,\N,Pathogenic,Optic atrophy & auditory neuropathy,missense_variant,27.4,\N,\N,OPA1
609059,3:193355765:G>C,NM_130837.2:c.1060G>C,NP_570850.2:p.Ala354Pro,11/31,\N,Pathogenic,Optic atrophy 1,missense_variant,26.7,\N,\N,OPA1
609060,3:193355769:G>A,NM_130837.2:c.1064G>A,NP_570850.2:p.Gly355Glu,11/31,\N,Pathogenic,Optic atrophy 1,missense_variant,27.7,\N,\N,OPA1
609061,3:193355774:A>C,NM_130837.2:c.1069A>C,NP_570850.2:p.Thr357Pro,11/31,\N,Pathogenic,Optic atrophy,missense_variant,25.3,\N,\N,OPA1
609062,3:193355779:T>C,NM_130837.2:c.1074T>C,NP_570850.2:p.Ser358=,11/31,\N,Unknown significance,\N,synonymous_variant,8.247,0.000244618,EXAC_SAS_AF,OPA1
609063,3:193355779:T>G,NM_130837.2:c.1074T>G,NP_570850.2:p.Ser358Arg,11/31,\N,Pathogenic,Optic atrophy,missense_variant,25.7,\N,\N,OPA1
609064,3:193355782:G>A,NM_130837.2:c.1077G>A,NP_570850.2:p.Val359=,11/31,\N,Unknown significance,\N,synonymous_variant,12.85,0.0008,1KG_AFR_AF,OPA1
609065,3:193355788:A>T,NM_130837.2:c.1083A>T,NP_570850.2:p.Glu361Asp,11/31,\N,Unknown significance,\N,missense_variant,26.4,0.0000610724,EXAC_SAS_AF,OPA1
609066,3:193355796:C>T,NM_015560.2:c.926C>T,NP_056375.2:p.Ala309Val,9/29,\N,Unknown significance,\N,missense_variant,28.9,\N,\N,OPA1
609067,3:193355798:C>G,NM_130837.2:c.1093C>G,NP_570850.2:p.Gln365Glu,11/31,\N,Unknown significance,\N,missense_variant,27.7,0.000115607,EXAC_EAS_AF,OPA1
609068,3:193355799:A>G,NM_130835.2:c.986A>G,NP_570848.1:p.Gln329Arg,10/30,\N,Pathogenic,Optic atrophy 1,missense_variant,24.4,0.0000300327,EXAC_NFE_AF,OPA1
609069,3:193355801:GC>G,NM_130837.2:c.1097del,NP_570850.2:p.Ala366ValfsTer11,11/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,35,\N,\N,OPA1
609070,3:193355802:C>A,NM_130837.2:c.1097C>A,NP_570850.2:p.Ala366Asp,11/31,\N,Unknown significance,\N,missense_variant,34,\N,\N,OPA1
609071,3:193355803:T>C,NM_130837.2:c.1098T>C,NP_570850.2:p.Ala366=,11/31,\N,Unknown significance,\N,synonymous_variant,8.253,0.0000150177,EXAC_NFE_AF,OPA1
609072,3:193355804:C>T,NM_130837.2:c.1099C>T,NP_570850.2:p.Arg367Ter,11/31,\N,Pathogenic,Optic atrophy 1,stop_gained,39,\N,\N,OPA1
609073,3:193355805:G>A,NM_130837.2:c.1100G>A,NP_570850.2:p.Arg367Gln,11/31,\N,Unknown significance,\N,missense_variant,34,0.000116279,EVS_EA_AF,OPA1
609074,3:193355807:AT>GA,NM_130837.2:c.1102_1103delinsGA,NP_570850.2:p.Ile368Glu,11/31,\N,Pathogenic,Optic atrophy 1,missense_variant,32,\N,\N,OPA1
609075,3:193355808:T>A,NM_130837.2:c.1103T>A,NP_570850.2:p.Ile368Lys,11/31,\N,Pathogenic,Optic atrophy 1,missense_variant,34,\N,\N,OPA1
609076,3:193355809:A>G,NM_130837.2:c.1104A>G,NP_570850.2:p.Ile368Met,11/31,\N,Unknown significance,\N,missense_variant,25.1,0.0000965251,EXAC_AFR_AF,OPA1
609077,3:193355816:A>T,NM_130837.2:c.1111A>T,NP_570850.2:p.Arg371Ter,11/31,\N,Pathogenic,Optic atrophy 1,stop_gained,35,\N,\N,OPA1
609078,3:193355820:G>C,NM_130837.2:c.1115G>C,NP_570850.2:p.Gly372Ala,11/31,\N,Unknown significance,\N,missense_variant,27.1,\N,\N,OPA1
609079,3:193355831:A>G,NM_130837.2:c.1126A>G,NP_570850.2:p.Met376Val,11/31,\N,Likely pathogenic,\N,missense_variant,25,\N,\N,OPA1
609080,3:193355833:G>A,NM_130837.2:c.1128G>A,NP_570850.2:p.Met376Ile,11/31,\N,Unknown significance,\N,missense_variant,33,\N,\N,OPA1
609081,3:193355837:ACACGTTCTC>A,NM_130837.2:c.1135_1143del,NP_570850.2:p.Arg379_Pro381del,11/31,\N,Pathogenic,Optic atrophy 1,inframe_deletion,23.1,\N,\N,OPA1
609082,3:193355839:A>G,NM_130837.2:c.1134A>G,NP_570850.2:p.Thr378=,11/31,\N,Unknown significance,\N,synonymous_variant,6.525,0.0000151236,EXAC_NFE_AF,OPA1
609083,3:193355840:C>T,NM_130837.2:c.1135C>T,NP_570850.2:p.Arg379Cys,11/31,\N,Unknown significance,\N,missense_variant,35,0.000313755,EXAC_SAS_AF,OPA1
609084,3:193355850:TTAAGG>T,NM_130837.2:c.1149+1_1149+5del,\N,11/31,11/30,Pathogenic,Optic atrophy 1,splice_donor_variant&coding_sequence_variant,35,\N,\N,OPA1
609085,3:193355853:A>G,NM_015560.2:c.983A>G,NP_056375.2:p.Lys328Arg,9/29,\N,Pathogenic,Optic atrophy 1,missense_variant&splice_region_variant,29,\N,\N,OPA1
609086,3:193355853:A>C,NM_015560.2:c.983A>C,NP_056375.2:p.Lys328Thr,9/29,\N,Unknown significance,\N,missense_variant&splice_region_variant,28.5,0.0000153412,EXAC_NFE_AF,OPA1
609087,3:193355854:G>A,NM_130837.2:c.1149G>A,NP_570850.2:p.Lys383=,11/31,\N,Pathogenic,Optic atrophy 1,splice_region_variant&synonymous_variant,20.6,\N,\N,OPA1
609088,3:193355855:G>T,NM_130837.2:c.1149+1G>T,\N,\N,11/30,Pathogenic,Optic atrophy,splice_donor_variant,24.7,\N,\N,OPA1
609089,3:193355856:T>A,NM_130837.2:c.1149+2T>A,\N,\N,11/30,Pathogenic,Optic atrophy 1,splice_donor_variant,25.8,\N,\N,OPA1
609090,3:193355857:A>T,NM_130837.2:c.1149+3A>T,\N,\N,11/30,Pathogenic,Optic atrophy 1,splice_region_variant&intron_variant,9.979,\N,\N,OPA1
609091,3:193355863:A>ACTTATTCATATTTT,NM_130837.2:c.1149+9_1149+10insCTTATTCATATTTT,\N,\N,11/30,Unknown significance,\N,intron_variant,0.907,\N,\N,OPA1
609092,3:193355863:A>ACTTATTCATATTTTTCTGATACCAAAT,NM_130837.2:c.1149+9_1149+10insCTTATTCATATTTTTCTGATACCAAAT,\N,\N,11/30,Unknown significance,\N,intron_variant,0.295,\N,\N,OPA1
609093,3:193355863:A>ACTTATTCATATTTTTCTGATACCAAATTAAAAT,NM_130837.2:c.1149+9_1149+10insCTTATTCATATTTTTCTGATACCAAATTAAAAT,\N,\N,11/30,Unknown significance,\N,intron_variant,0.171,\N,\N,OPA1
609094,3:193355866:G>A,NM_130837.2:c.1149+12G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,8.254,0.001,1KG_EAS_AF,OPA1
609095,3:193355867:G>A,NM_130837.2:c.1149+13G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,8.062,0.0000941088,EXAC_AMR_AF,OPA1
609096,3:193355869:C>T,NM_130837.2:c.1149+15C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,7.129,0.000232558,EVS_EA_AF,OPA1
609097,3:193355870:G>A,NM_130837.2:c.1149+16G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,2.392,0.0000958038,EXAC_AMR_AF,OPA1
609098,3:193355876:G>A,NM_130837.2:c.1149+22G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,0.139,0.0000323144,EXAC_NFE_AF,OPA1
609099,3:193355878:G>A,NM_130837.2:c.1149+24G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,4.153,0.000126775,EXAC_EAS_AF,OPA1
609100,3:193355881:G>A,NM_130837.2:c.1149+27G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,4.809,0.00226963,EVS_AA_AF,OPA1
609101,3:193355887:T>C,NM_130837.2:c.1149+33T>C,\N,\N,11/30,Unknown significance,\N,intron_variant,4.053,0.000016415,EXAC_NFE_AF,OPA1
609102,3:193355889:G>A,NM_130837.2:c.1149+35G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,5.81,0.000270636,EXAC_SAS_AF,OPA1
609103,3:193355890:G>T,NM_130837.2:c.1149+36G>T,\N,\N,11/30,Unknown significance,\N,intron_variant,2.679,0.0000679163,EXAC_SAS_AF,OPA1
609104,3:193355901:C>A,NM_130837.2:c.1149+47C>A,\N,\N,11/30,Unknown significance,\N,intron_variant,5.64,0.0000692905,EXAC_SAS_AF,OPA1
609105,3:193355901:C>T,NM_130837.2:c.1149+47C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,4.637,0.000227066,EVS_AA_AF,OPA1
609106,3:193355906:G>A,NM_130837.2:c.1149+52G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,2.204,0.00128755,EXAC_AMR_AF,OPA1
609107,3:193355932:G>A,NM_130837.2:c.1149+78G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,3.829,\N,\N,OPA1
609108,3:193355946:A>G,NM_130837.2:c.1149+92A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,4.213,\N,\N,OPA1
609109,3:193355960:T>C,NM_130837.2:c.1149+106T>C,\N,\N,11/30,Unknown significance,\N,intron_variant,1.986,\N,\N,OPA1
609110,3:193355963:A>G,NM_130837.2:c.1149+109A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,2.742,0.0023,1KG_AFR_AF,OPA1
609111,3:193356032:G>A,NM_130837.2:c.1149+178G>A,\N,\N,11/30,Benign,\N,intron_variant,6.179,0.0234,1KG_AFR_AF,OPA1
609112,3:193356035:G>A,NM_130837.2:c.1149+181G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,6.139,0.0008,1KG_AFR_AF,OPA1
609113,3:193356058:A>G,NM_130837.2:c.1149+204A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,3.353,0.0029,1KG_AMR_AF,OPA1
609114,3:193356102:A>C,NM_130837.2:c.1149+248A>C,\N,\N,11/30,Unknown significance,\N,intron_variant,0.798,\N,\N,OPA1
609115,3:193356117:A>T,NM_130837.2:c.1149+263A>T,\N,\N,11/30,Unknown significance,\N,intron_variant,2.389,0.001,1KG_SAS_AF,OPA1
609116,3:193356119:G>T,NM_130837.2:c.1149+265G>T,\N,\N,11/30,Unknown significance,\N,intron_variant,3.332,\N,\N,OPA1
609117,3:193356173:G>A,NM_130837.2:c.1149+319G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,13.06,\N,\N,OPA1
609118,3:193356177:T>C,NM_130837.2:c.1149+323T>C,\N,\N,11/30,Unknown significance,\N,intron_variant,10.42,\N,\N,OPA1
609119,3:193356179:T>C,NM_130837.2:c.1149+325T>C,\N,\N,11/30,Unknown significance,\N,intron_variant,8.215,0.004,1KG_EAS_AF,OPA1
609120,3:193356180:T>G,NM_130837.2:c.1149+326T>G,\N,\N,11/30,Unknown significance,\N,intron_variant,9.725,\N,\N,OPA1
609121,3:193356192:G>A,NM_130837.2:c.1149+338G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,0.743,0.0008,1KG_AFR_AF,OPA1
609122,3:193356221:A>G,NM_130837.2:c.1149+367A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,0.643,0.0029,1KG_AMR_AF,OPA1
609123,3:193356238:A>C,NM_130837.2:c.1149+384A>C,\N,\N,11/30,Unknown significance,\N,intron_variant,1.513,\N,\N,OPA1
609124,3:193356253:T>C,NM_130837.2:c.1149+399T>C,\N,\N,11/30,Unknown significance,\N,intron_variant,0.813,0.0015,1KG_AFR_AF,OPA1
609125,3:193356264:A>G,NM_130837.2:c.1149+410A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,0.264,0.001,1KG_EAS_AF,OPA1
609126,3:193356305:G>A,NM_130837.2:c.1149+451G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,2.02,0.001,1KG_EUR_AF,OPA1
609127,3:193356312:C>G,NM_130837.2:c.1149+458C>G,\N,\N,11/30,Unknown significance,\N,intron_variant,1.416,\N,\N,OPA1
609128,3:193356338:A>T,NM_130837.2:c.1149+484A>T,\N,\N,11/30,Unknown significance,\N,intron_variant,5.835,\N,\N,OPA1
609129,3:193356349:A>G,NM_130837.2:c.1149+495A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,0.088,0.0015,1KG_AFR_AF,OPA1
609130,3:193356449:GA>G,NM_130837.2:c.1149+596del,\N,\N,11/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
609131,3:193356474:A>G,NM_130837.2:c.1149+620A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,7.464,0.001,1KG_EUR_AF,OPA1
609132,3:193356489:T>G,NM_130837.2:c.1149+635T>G,\N,\N,11/30,Unknown significance,\N,intron_variant,7.132,0.0008,1KG_AFR_AF,OPA1
609133,3:193356534:A>G,NM_130837.2:c.1149+680A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,5.442,\N,\N,OPA1
609134,3:193356561:AT>A,NM_130837.2:c.1149+711del,\N,\N,11/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
609135,3:193356576:G>A,NM_130837.2:c.1149+722G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,0.254,\N,\N,OPA1
609136,3:193356580:C>T,NM_130837.2:c.1149+726C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,0.392,0.002,1KG_SAS_AF,OPA1
609137,3:193356594:G>A,NM_130837.2:c.1149+740G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,1.642,\N,\N,OPA1
609138,3:193356646:T>C,NM_130837.2:c.1149+792T>C,\N,\N,11/30,Unknown significance,\N,intron_variant,1.567,0.0008,1KG_AFR_AF,OPA1
609139,3:193356674:T>C,NM_130837.2:c.1149+820T>C,\N,\N,11/30,Unknown significance,\N,intron_variant,1.433,\N,\N,OPA1
609140,3:193356695:G>A,NM_130837.2:c.1149+841G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,2.769,\N,\N,OPA1
609141,3:193356728:A>G,NM_130837.2:c.1149+874A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,3.378,0.0014,1KG_AMR_AF,OPA1
609142,3:193356762:A>G,NM_130837.2:c.1149+908A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,2.587,\N,\N,OPA1
609143,3:193356768:A>G,NM_130837.2:c.1149+914A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,3.932,0.0015,1KG_AFR_AF,OPA1
609144,3:193356770:A>G,NM_130837.2:c.1149+916A>G,\N,\N,11/30,Benign,\N,intron_variant,4.218,0.0875,1KG_EUR_AF,OPA1
609145,3:193356781:AATG>A,NM_130837.2:c.1149+930_1149+932del,\N,\N,11/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
609146,3:193356796:G>C,NM_130837.2:c.1149+942G>C,\N,\N,11/30,Unknown significance,\N,intron_variant,0.338,\N,\N,OPA1
609147,3:193356804:T>C,NM_130837.2:c.1149+950T>C,\N,\N,11/30,Unknown significance,\N,intron_variant,2.084,\N,\N,OPA1
609148,3:193356809:CAA>C,NM_130837.2:c.1149+956_1149+957del,\N,\N,11/30,Benign,\N,intron_variant,4.316,0.0265,1KG_AFR_AF,OPA1
609149,3:193356863:C>T,NM_130837.2:c.1149+1009C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,3.524,0.001,1KG_SAS_AF,OPA1
609150,3:193356869:G>T,NM_130837.2:c.1149+1015G>T,\N,\N,11/30,Unknown significance,\N,intron_variant,1.647,\N,\N,OPA1
609151,3:193356898:A>G,NM_130837.2:c.1149+1044A>G,\N,\N,11/30,Benign,\N,intron_variant,0.945,0.0272,1KG_AFR_AF,OPA1
609152,3:193356944:C>G,NM_130837.2:c.1149+1090C>G,\N,\N,11/30,Unknown significance,\N,intron_variant,3.978,\N,\N,OPA1
609153,3:193356962:G>A,NM_130837.2:c.1149+1108G>A,\N,\N,11/30,Benign,\N,intron_variant,0.33,0.0159,1KG_AFR_AF,OPA1
609154,3:193356963:G>C,NM_130837.2:c.1149+1109G>C,\N,\N,11/30,Unknown significance,\N,intron_variant,0.577,0.001,1KG_SAS_AF,OPA1
609155,3:193356981:A>G,NM_130837.2:c.1149+1127A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,4.491,0.002,1KG_SAS_AF,OPA1
609156,3:193357057:T>G,NM_130837.2:c.1149+1203T>G,\N,\N,11/30,Unknown significance,\N,intron_variant,1.109,\N,\N,OPA1
609157,3:193357076:G>T,NM_130837.2:c.1149+1222G>T,\N,\N,11/30,Unknown significance,\N,intron_variant,1.897,0.001,1KG_EUR_AF,OPA1
609158,3:193357083:A>G,NM_130837.2:c.1149+1229A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,4.957,0.001,1KG_SAS_AF,OPA1
609159,3:193357090:T>A,NM_130837.2:c.1149+1236T>A,\N,\N,11/30,Unknown significance,\N,intron_variant,3.352,0.001,1KG_EAS_AF,OPA1
609160,3:193357101:A>G,NM_130837.2:c.1149+1247A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,2.152,0.0008,1KG_AFR_AF,OPA1
609161,3:193357124:GT>G,NM_130837.2:c.1149+1272del,\N,\N,11/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
609162,3:193357150:A>G,NM_130837.2:c.1149+1296A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,5.361,0.0029,1KG_AMR_AF,OPA1
609163,3:193357231:G>A,NM_130837.2:c.1149+1377G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,6.806,\N,\N,OPA1
609164,3:193357323:A>G,NM_130837.2:c.1149+1469A>G,\N,\N,11/30,Benign,\N,intron_variant,2.954,0.0082,1KG_SAS_AF,OPA1
609165,3:193357348:C>T,NM_130837.2:c.1149+1494C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,4.115,0.0014,1KG_AMR_AF,OPA1
609166,3:193357349:G>A,NM_130837.2:c.1149+1495G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,1.095,\N,\N,OPA1
609167,3:193357367:T>C,NM_130837.2:c.1149+1513T>C,\N,\N,11/30,Unknown significance,\N,intron_variant,4.613,\N,\N,OPA1
609168,3:193357371:C>T,NM_130837.2:c.1149+1517C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,5.382,\N,\N,OPA1
609169,3:193357372:G>A,NM_130837.2:c.1149+1518G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,4.074,\N,\N,OPA1
609170,3:193357386:C>A,NM_130837.2:c.1149+1532C>A,\N,\N,11/30,Unknown significance,\N,intron_variant,5.22,\N,\N,OPA1
609171,3:193357386:C>G,NM_130837.2:c.1149+1532C>G,\N,\N,11/30,Unknown significance,\N,intron_variant,3.611,\N,\N,OPA1
609172,3:193357402:A>T,NM_130837.2:c.1149+1548A>T,\N,\N,11/30,Unknown significance,\N,intron_variant,0.935,\N,\N,OPA1
609173,3:193357406:G>A,NM_130837.2:c.1149+1552G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,3.531,\N,\N,OPA1
609174,3:193357408:G>A,NM_130837.2:c.1149+1554G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,2.106,0.001,1KG_EAS_AF,OPA1
609175,3:193357455:C>T,NM_130837.2:c.1149+1601C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,3.075,\N,\N,OPA1
609176,3:193357465:A>G,NM_130837.2:c.1149+1611A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,7.139,\N,\N,OPA1
609177,3:193357468:A>G,NM_130837.2:c.1149+1614A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,7.06,\N,\N,OPA1
609178,3:193357468:A>T,NM_130837.2:c.1149+1614A>T,\N,\N,11/30,Unknown significance,\N,intron_variant,5.737,\N,\N,OPA1
609179,3:193357490:C>T,NM_130837.2:c.1149+1636C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,5.952,0.001,1KG_EAS_AF,OPA1
609180,3:193357496:A>G,NM_130837.2:c.1149+1642A>G,\N,\N,11/30,Benign,\N,intron_variant,7.035,0.0179,1KG_EAS_AF,OPA1
609181,3:193357570:AG>A,NM_130837.2:c.1149+1718del,\N,\N,11/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
609182,3:193357588:G>A,NM_130837.2:c.1149+1734G>A,\N,\N,11/30,Benign,\N,intron_variant,5.547,0.0091,1KG_AFR_AF,OPA1
609183,3:193357610:T>G,NM_130837.2:c.1149+1756T>G,\N,\N,11/30,Unknown significance,\N,intron_variant,7.151,\N,\N,OPA1
609184,3:193357665:T>G,NM_130837.2:c.1149+1811T>G,\N,\N,11/30,Unknown significance,\N,intron_variant,6.511,\N,\N,OPA1
609185,3:193357699:G>A,NM_130837.2:c.1149+1845G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,0.727,0.001,1KG_SAS_AF,OPA1
609186,3:193357721:GGA>G,NM_130837.2:c.1149+1881_1149+1882del,\N,\N,11/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
609187,3:193357721:GGAGA>G,NM_130837.2:c.1149+1879_1149+1882del,\N,\N,11/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
609188,3:193357735:A>C,NM_130837.2:c.1149+1881A>C,\N,\N,11/30,Unknown significance,\N,intron_variant,0.083,0.0015,1KG_AFR_AF,OPA1
609189,3:193357737:T>A,NM_130837.2:c.1149+1883T>A,\N,\N,11/30,Unknown significance,\N,intron_variant,6.767,0.0014,1KG_AMR_AF,OPA1
609190,3:193357742:A>G,NM_130837.2:c.1149+1888A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,1.174,0.001,1KG_EAS_AF,OPA1
609191,3:193357749:A>G,NM_130837.2:c.1149+1895A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,1.336,\N,\N,OPA1
609192,3:193357782:T>A,NM_130837.2:c.1149+1928T>A,\N,\N,11/30,Unknown significance,\N,intron_variant,7.553,0.0008,1KG_AFR_AF,OPA1
609193,3:193357789:T>C,NM_130837.2:c.1149+1935T>C,\N,\N,11/30,Unknown significance,\N,intron_variant,5.386,0.001,1KG_EUR_AF,OPA1
609194,3:193357830:G>T,NM_130837.2:c.1149+1976G>T,\N,\N,11/30,Unknown significance,\N,intron_variant,2.358,0.0008,1KG_AFR_AF,OPA1
609195,3:193357837:A>G,NM_130837.2:c.1149+1983A>G,\N,\N,11/30,Benign,\N,intron_variant,4.171,0.1051,1KG_AFR_AF,OPA1
609196,3:193357888:A>G,NM_130837.2:c.1149+2034A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,3.074,\N,\N,OPA1
609197,3:193357896:T>C,NM_130837.2:c.1149+2042T>C,\N,\N,11/30,Unknown significance,\N,intron_variant,2.529,0.001,1KG_EUR_AF,OPA1
609198,3:193357999:G>C,NM_130837.2:c.1149+2145G>C,\N,\N,11/30,Unknown significance,\N,intron_variant,1.439,\N,\N,OPA1
609199,3:193358002:A>G,NM_130837.2:c.1149+2148A>G,\N,\N,11/30,Benign,\N,intron_variant,5.366,0.0053,1KG_AFR_AF,OPA1
609200,3:193358037:A>T,NM_130837.2:c.1149+2183A>T,\N,\N,11/30,Unknown significance,\N,intron_variant,0.752,\N,\N,OPA1
609201,3:193358061:A>T,NM_130837.2:c.1149+2207A>T,\N,\N,11/30,Unknown significance,\N,intron_variant,1.461,\N,\N,OPA1
609202,3:193358126:G>T,NM_130837.2:c.1149+2272G>T,\N,\N,11/30,Unknown significance,\N,intron_variant,0.253,0.0023,1KG_AFR_AF,OPA1
609203,3:193358144:C>T,NM_130837.2:c.1149+2290C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,1.412,0.0014,1KG_AMR_AF,OPA1
609204,3:193358153:A>C,NM_130837.2:c.1149+2299A>C,\N,\N,11/30,Unknown significance,\N,intron_variant,1.008,0.001,1KG_SAS_AF,OPA1
609205,3:193358177:G>A,NM_130837.2:c.1149+2323G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,0.778,\N,\N,OPA1
609206,3:193358210:C>T,NM_130837.2:c.1150-2344C>T,\N,\N,11/30,Benign,\N,intron_variant,12.47,0.0235,1KG_SAS_AF,OPA1
609207,3:193358231:A>G,NM_130837.2:c.1150-2323A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,8.547,0.001,1KG_EUR_AF,OPA1
609208,3:193358245:C>T,NM_130837.2:c.1150-2309C>T,\N,\N,11/30,Benign,\N,intron_variant,6.515,0.138,1KG_SAS_AF,OPA1
609209,3:193358246:G>A,NM_130837.2:c.1150-2308G>A,\N,\N,11/30,Benign,\N,intron_variant,2.767,0.0179,1KG_EAS_AF,OPA1
609210,3:193358250:A>G,NM_130837.2:c.1150-2304A>G,\N,\N,11/30,Benign,\N,intron_variant,5.93,0.0058,1KG_AMR_AF,OPA1
609211,3:193358260:T>C,NM_130837.2:c.1150-2294T>C,\N,\N,11/30,Unknown significance,\N,intron_variant,4.804,\N,\N,OPA1
609212,3:193358279:C>T,NM_130837.2:c.1150-2275C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,1.025,\N,\N,OPA1
609213,3:193358280:G>A,NM_130837.2:c.1150-2274G>A,\N,\N,11/30,Benign,\N,intron_variant,1.147,0.0136,1KG_AFR_AF,OPA1
609214,3:193358298:G>C,NM_130837.2:c.1150-2256G>C,\N,\N,11/30,Unknown significance,\N,intron_variant,1.425,0.0008,1KG_AFR_AF,OPA1
609215,3:193358346:T>C,NM_130837.2:c.1150-2208T>C,\N,\N,11/30,Unknown significance,\N,intron_variant,2.729,0.001,1KG_EAS_AF,OPA1
609216,3:193358354:A>T,NM_130837.2:c.1150-2200A>T,\N,\N,11/30,Unknown significance,\N,intron_variant,2.992,0.001,1KG_EAS_AF,OPA1
609217,3:193358369:A>C,NM_130837.2:c.1150-2185A>C,\N,\N,11/30,Unknown significance,\N,intron_variant,1.42,0.0014,1KG_AMR_AF,OPA1
609218,3:193358378:G>A,NM_130837.2:c.1150-2176G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,4.808,\N,\N,OPA1
609219,3:193358474:T>G,NM_130837.2:c.1150-2080T>G,\N,\N,11/30,Unknown significance,\N,intron_variant,10.37,\N,\N,OPA1
609220,3:193358500:T>TA,NM_130837.2:c.1150-2051dup,\N,\N,11/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
609221,3:193358540:T>C,NM_130837.2:c.1150-2014T>C,\N,\N,11/30,Unknown significance,\N,intron_variant,1.225,\N,\N,OPA1
609222,3:193358541:C>T,NM_130837.2:c.1150-2013C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,1.523,\N,\N,OPA1
609223,3:193358546:T>G,NM_130837.2:c.1150-2008T>G,\N,\N,11/30,Unknown significance,\N,intron_variant,2.613,0.002,1KG_EUR_AF,OPA1
609224,3:193358554:T>C,NM_130837.2:c.1150-2000T>C,\N,\N,11/30,Unknown significance,\N,intron_variant,0.918,\N,\N,OPA1
609225,3:193358575:T>C,NM_130837.2:c.1150-1979T>C,\N,\N,11/30,Unknown significance,\N,intron_variant,3.246,0.0015,1KG_AFR_AF,OPA1
609226,3:193358616:G>T,NM_130837.2:c.1150-1938G>T,\N,\N,11/30,Unknown significance,\N,intron_variant,1.648,\N,\N,OPA1
609227,3:193358622:A>G,NM_130837.2:c.1150-1932A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,3.652,0.001,1KG_EAS_AF,OPA1
609228,3:193358625:C>CAGT,NM_130837.2:c.1150-1928_1150-1926dup,\N,\N,11/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
609229,3:193358644:A>G,NM_130837.2:c.1150-1910A>G,\N,\N,11/30,Benign,\N,intron_variant,4.949,0.062,1KG_AFR_AF,OPA1
609230,3:193358650:A>C,NM_130837.2:c.1150-1904A>C,\N,\N,11/30,Unknown significance,\N,intron_variant,3.09,0.0015,1KG_AFR_AF,OPA1
609231,3:193358672:G>A,NM_130837.2:c.1150-1882G>A,\N,\N,11/30,Benign,\N,intron_variant,0.927,0.4284,1KG_EUR_AF,OPA1
609232,3:193358716:A>G,NM_130837.2:c.1150-1838A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,5.561,\N,\N,OPA1
609233,3:193358724:G>A,NM_130837.2:c.1150-1830G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,3.719,\N,\N,OPA1
609234,3:193358732:C>T,NM_130837.2:c.1150-1822C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,4.607,\N,\N,OPA1
609235,3:193358734:A>G,NM_130837.2:c.1150-1820A>G,\N,\N,11/30,Benign,\N,intron_variant,3.642,0.411,1KG_SAS_AF,OPA1
609236,3:193358745:C>T,NM_130837.2:c.1150-1809C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,0.68,0.0015,1KG_AFR_AF,OPA1
609237,3:193358746:G>A,NM_130837.2:c.1150-1808G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,0.454,0.0029,1KG_AMR_AF,OPA1
609238,3:193358758:A>T,NM_130837.2:c.1150-1796A>T,\N,\N,11/30,Unknown significance,\N,intron_variant,3.787,\N,\N,OPA1
609239,3:193358779:G>T,NM_130837.2:c.1150-1775G>T,\N,\N,11/30,Unknown significance,\N,intron_variant,1.412,0.0008,1KG_AFR_AF,OPA1
609240,3:193358813:C>T,NM_130837.2:c.1150-1741C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,4.239,0.0008,1KG_AFR_AF,OPA1
609241,3:193358817:C>T,NM_130837.2:c.1150-1737C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,1.963,0.004,1KG_EAS_AF,OPA1
609242,3:193358818:G>A,NM_130837.2:c.1150-1736G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,0.822,\N,\N,OPA1
609243,3:193358898:C>T,NM_130837.2:c.1150-1656C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,5.365,0.0014,1KG_AMR_AF,OPA1
609244,3:193358944:A>G,NM_130837.2:c.1150-1610A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,2.944,0.0014,1KG_AMR_AF,OPA1
609245,3:193358980:A>G,NM_130837.2:c.1150-1574A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,4.663,0.0008,1KG_AFR_AF,OPA1
609246,3:193358988:TTAA>T,NM_130837.2:c.1150-1564_1150-1562del,\N,\N,11/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
609247,3:193358995:T>A,NM_130837.2:c.1150-1559T>A,\N,\N,11/30,Unknown significance,\N,intron_variant,11.16,\N,\N,OPA1
609248,3:193359013:G>A,NM_130837.2:c.1150-1541G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,1.519,\N,\N,OPA1
609249,3:193359034:A>G,NM_130837.2:c.1150-1520A>G,\N,\N,11/30,Benign,\N,intron_variant,0.473,0.0257,1KG_AFR_AF,OPA1
609250,3:193359054:C>T,NM_130837.2:c.1150-1500C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,4.679,\N,\N,OPA1
609251,3:193359055:G>A,NM_130837.2:c.1150-1499G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,1.982,0.0023,1KG_AFR_AF,OPA1
609252,3:193359104:C>G,NM_130837.2:c.1150-1450C>G,\N,\N,11/30,Unknown significance,\N,intron_variant,1.562,0.0014,1KG_AMR_AF,OPA1
609253,3:193359113:C>T,NM_130837.2:c.1150-1441C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,1.975,\N,\N,OPA1
609254,3:193359115:GT>G,NM_130837.2:c.1150-1433del,\N,\N,11/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
609255,3:193359132:A>G,NM_130837.2:c.1150-1422A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,1.921,\N,\N,OPA1
609256,3:193359148:A>G,NM_130837.2:c.1150-1406A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,3.314,\N,\N,OPA1
609257,3:193359172:T>C,NM_130837.2:c.1150-1382T>C,\N,\N,11/30,Unknown significance,\N,intron_variant,3.511,\N,\N,OPA1
609258,3:193359192:C>G,NM_130837.2:c.1150-1362C>G,\N,\N,11/30,Benign,\N,intron_variant,4.882,0.3224,1KG_EAS_AF,OPA1
609259,3:193359193:T>C,NM_130837.2:c.1150-1361T>C,\N,\N,11/30,Benign,\N,intron_variant,8.028,0.428,1KG_AMR_AF,OPA1
609260,3:193359205:A>T,NM_130837.2:c.1150-1349A>T,\N,\N,11/30,Benign,\N,intron_variant,1.473,0.5855,1KG_AFR_AF,OPA1
609261,3:193359217:G>A,NM_130837.2:c.1150-1337G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,0.531,0.004,1KG_EAS_AF,OPA1
609262,3:193359233:C>T,NM_130837.2:c.1150-1321C>T,\N,\N,11/30,Benign,\N,intron_variant,4.082,0.0182,1KG_AFR_AF,OPA1
609263,3:193359245:GGTTTT>G,NM_130837.2:c.1150-1297_1150-1293del,\N,\N,11/30,Benign,\N,intron_variant,1.751,1,1KG_ALL_AF|1KG_AFR_AF|1KG_AMR_AF|1KG_EAS_AF|1KG_EUR_AF|1KG_SAS_AF,OPA1
609264,3:193359249:T>G,NM_130837.2:c.1150-1305T>G,\N,\N,11/30,Unknown significance,\N,intron_variant,3.656,\N,\N,OPA1
609265,3:193359250:T>G,NM_130837.2:c.1150-1304T>G,\N,\N,11/30,Unknown significance,\N,intron_variant,0.378,\N,\N,OPA1
609266,3:193359258:T>C,NM_130837.2:c.1150-1296T>C,\N,\N,11/30,Unknown significance,\N,intron_variant,1.513,\N,\N,OPA1
609267,3:193359301:G>A,NM_130837.2:c.1150-1253G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,1.786,\N,\N,OPA1
609268,3:193359304:C>T,NM_130837.2:c.1150-1250C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,4.327,\N,\N,OPA1
609269,3:193359312:C>T,NM_130837.2:c.1150-1242C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,1.674,0.002,1KG_EUR_AF,OPA1
609270,3:193359330:C>T,NM_130837.2:c.1150-1224C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,1.348,\N,\N,OPA1
609271,3:193359332:G>A,NM_130837.2:c.1150-1222G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,3.773,0.0008,1KG_AFR_AF,OPA1
609272,3:193359356:C>A,NM_130837.2:c.1150-1198C>A,\N,\N,11/30,Unknown significance,\N,intron_variant,4.519,0.0045,1KG_AFR_AF,OPA1
609273,3:193359359:G>C,NM_130837.2:c.1150-1195G>C,\N,\N,11/30,Unknown significance,\N,intron_variant,0.582,\N,\N,OPA1
609274,3:193359378:T>C,NM_130837.2:c.1150-1176T>C,\N,\N,11/30,Unknown significance,\N,intron_variant,5.312,0.0014,1KG_AMR_AF,OPA1
609275,3:193359410:A>G,NM_130837.2:c.1150-1144A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,8.534,\N,\N,OPA1
609276,3:193359442:T>C,NM_130837.2:c.1150-1112T>C,\N,\N,11/30,Unknown significance,\N,intron_variant,6.757,0.001,1KG_SAS_AF,OPA1
609277,3:193359477:A>C,NM_130837.2:c.1150-1077A>C,\N,\N,11/30,Unknown significance,\N,intron_variant,0.544,0.003,1KG_EAS_AF,OPA1
609278,3:193359480:T>C,NM_130837.2:c.1150-1074T>C,\N,\N,11/30,Unknown significance,\N,intron_variant,9.222,0.0008,1KG_AFR_AF,OPA1
609279,3:193359482:G>T,NM_130837.2:c.1150-1072G>T,\N,\N,11/30,Unknown significance,\N,intron_variant,8.967,0.001,1KG_EAS_AF,OPA1
609280,3:193359493:T>C,NM_130837.2:c.1150-1061T>C,\N,\N,11/30,Unknown significance,\N,intron_variant,12.57,0.0008,1KG_AFR_AF,OPA1
609281,3:193359494:A>T,NM_130837.2:c.1150-1060A>T,\N,\N,11/30,Unknown significance,\N,intron_variant,11.89,\N,\N,OPA1
609282,3:193359529:A>G,NM_130837.2:c.1150-1025A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,2.602,0.002,1KG_EAS_AF,OPA1
609283,3:193359543:G>C,NM_130837.2:c.1150-1011G>C,\N,\N,11/30,Unknown significance,\N,intron_variant,0.817,\N,\N,OPA1
609284,3:193359552:G>A,NM_130837.2:c.1150-1002G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,1.613,\N,\N,OPA1
609285,3:193359565:A>G,NM_130837.2:c.1150-989A>G,\N,\N,11/30,Benign,\N,intron_variant,0.146,0.5741,1KG_AFR_AF,OPA1
609286,3:193359595:T>C,NM_130837.2:c.1150-959T>C,\N,\N,11/30,Unknown significance,\N,intron_variant,3.245,\N,\N,OPA1
609287,3:193359607:G>A,NM_130837.2:c.1150-947G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,2.567,\N,\N,OPA1
609288,3:193359610:A>G,NM_130837.2:c.1150-944A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,3.337,\N,\N,OPA1
609289,3:193359641:T>A,NM_130837.2:c.1150-913T>A,\N,\N,11/30,Unknown significance,\N,intron_variant,0.954,0.0008,1KG_AFR_AF,OPA1
609290,3:193359720:A>G,NM_130837.2:c.1150-834A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,0.308,\N,\N,OPA1
609291,3:193359724:C>T,NM_130837.2:c.1150-830C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,0.862,0.0008,1KG_AFR_AF,OPA1
609292,3:193359738:T>C,NM_130837.2:c.1150-816T>C,\N,\N,11/30,Unknown significance,\N,intron_variant,2.485,\N,\N,OPA1
609293,3:193359758:T>G,NM_130837.2:c.1150-796T>G,\N,\N,11/30,Unknown significance,\N,intron_variant,1.093,0.0031,1KG_SAS_AF,OPA1
609294,3:193359769:G>A,NM_130837.2:c.1150-785G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,0.631,\N,\N,OPA1
609295,3:193359773:C>T,NM_130837.2:c.1150-781C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,0.161,0.0008,1KG_AFR_AF,OPA1
609296,3:193359797:C>T,NM_130837.2:c.1150-757C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,0.712,0.0008,1KG_AFR_AF,OPA1
609297,3:193359808:G>C,NM_130837.2:c.1150-746G>C,\N,\N,11/30,Unknown significance,\N,intron_variant,0.636,\N,\N,OPA1
609298,3:193359829:C>T,NM_130837.2:c.1150-725C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,1.094,\N,\N,OPA1
609299,3:193359830:G>A,NM_130837.2:c.1150-724G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,0.202,\N,\N,OPA1
609300,3:193359831:C>T,NM_130837.2:c.1150-723C>T,\N,\N,11/30,Benign,\N,intron_variant,1.029,0.005,1KG_EAS_AF,OPA1
609301,3:193359832:G>A,NM_130837.2:c.1150-722G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,0.038,\N,\N,OPA1
609302,3:193359852:C>A,NM_130837.2:c.1150-702C>A,\N,\N,11/30,Unknown significance,\N,intron_variant,3.831,0.001,1KG_EAS_AF,OPA1
609303,3:193359854:G>A,NM_130837.2:c.1150-700G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,0.534,\N,\N,OPA1
609304,3:193359863:C>A,NM_130837.2:c.1150-691C>A,\N,\N,11/30,Unknown significance,\N,intron_variant,2.956,0.0015,1KG_AFR_AF,OPA1
609305,3:193359866:C>T,NM_130837.2:c.1150-688C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,2.33,0.001,1KG_EAS_AF,OPA1
609306,3:193359898:C>T,NM_130837.2:c.1150-656C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,2.46,0.001,1KG_SAS_AF,OPA1
609307,3:193359933:A>G,NM_130837.2:c.1150-621A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,4.233,\N,\N,OPA1
609308,3:193359942:C>T,NM_130837.2:c.1150-612C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,5.844,\N,\N,OPA1
609309,3:193359970:G>A,NM_130837.2:c.1150-584G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,4.639,0.001,1KG_EUR_AF,OPA1
609310,3:193359973:G>A,NM_130837.2:c.1150-581G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,0.273,0.003,1KG_EAS_AF,OPA1
609311,3:193360036:A>G,NM_130837.2:c.1150-518A>G,\N,\N,11/30,Benign,\N,intron_variant,1.281,0.0133,1KG_SAS_AF,OPA1
609312,3:193360073:G>T,NM_130837.2:c.1150-481G>T,\N,\N,11/30,Unknown significance,\N,intron_variant,0.27,\N,\N,OPA1
609313,3:193360083:G>A,NM_130837.2:c.1150-471G>A,\N,\N,11/30,Benign,\N,intron_variant,2.725,0.0053,1KG_AFR_AF,OPA1
609314,3:193360096:CT>C,NM_130837.2:c.1150-457del,\N,\N,11/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
609315,3:193360113:C>T,NM_130837.2:c.1150-441C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,7.072,0.0014,1KG_AMR_AF,OPA1
609316,3:193360116:C>T,NM_130837.2:c.1150-438C>T,\N,\N,11/30,Benign,\N,intron_variant,7.826,0.0257,1KG_AFR_AF,OPA1
609317,3:193360118:C>G,NM_130837.2:c.1150-436C>G,\N,\N,11/30,Unknown significance,\N,intron_variant,7.826,0.001,1KG_EUR_AF,OPA1
609318,3:193360140:A>G,NM_130837.2:c.1150-414A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,4.056,0.001,1KG_SAS_AF,OPA1
609319,3:193360145:G>A,NM_130837.2:c.1150-409G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,0.285,0.0029,1KG_AMR_AF,OPA1
609320,3:193360171:C>T,NM_130837.2:c.1150-383C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,13.94,0.0008,1KG_AFR_AF,OPA1
609321,3:193360178:C>T,NM_130837.2:c.1150-376C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,15.53,\N,\N,OPA1
609322,3:193360197:A>C,NM_130837.2:c.1150-357A>C,\N,\N,11/30,Unknown significance,\N,intron_variant,10.93,0.001,1KG_EAS_AF,OPA1
609323,3:193360218:A>C,NM_130837.2:c.1150-336A>C,\N,\N,11/30,Unknown significance,\N,intron_variant,9.827,0.001,1KG_EUR_AF,OPA1
609324,3:193360259:C>G,NM_130837.2:c.1150-295C>G,\N,\N,11/30,Unknown significance,\N,intron_variant,1.801,0.001,1KG_EAS_AF,OPA1
609325,3:193360287:G>A,NM_130837.2:c.1150-267G>A,\N,\N,11/30,Unknown significance,\N,intron_variant,16.38,\N,\N,OPA1
609326,3:193360304:C>T,NM_130837.2:c.1150-250C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,11.39,0.003,1KG_EAS_AF,OPA1
609327,3:193360305:G>A,NM_130837.2:c.1150-249G>A,\N,\N,11/30,Benign,\N,intron_variant,12.38,0.0123,1KG_SAS_AF,OPA1
609328,3:193360322:A>G,NM_130837.2:c.1150-232A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,12.41,\N,\N,OPA1
609329,3:193360343:C>T,NM_130837.2:c.1150-211C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,7.631,0.0014,1KG_AMR_AF,OPA1
609330,3:193360353:A>G,NM_130837.2:c.1150-201A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,2.852,\N,\N,OPA1
609331,3:193360357:A>G,NM_130837.2:c.1150-197A>G,\N,\N,11/30,Benign,\N,intron_variant,1.412,0.0099,1KG_EAS_AF,OPA1
609332,3:193360364:C>G,NM_130837.2:c.1150-190C>G,\N,\N,11/30,Unknown significance,\N,intron_variant,2.531,0.001,1KG_EAS_AF,OPA1
609333,3:193360393:A>G,NM_130837.2:c.1150-161A>G,\N,\N,11/30,Benign,\N,intron_variant,4.718,0.0272,1KG_AFR_AF,OPA1
609334,3:193360403:T>C,NM_130837.2:c.1150-151T>C,\N,\N,11/30,Unknown significance,\N,intron_variant,4.067,0.0015,1KG_AFR_AF,OPA1
609335,3:193360425:C>T,NM_130837.2:c.1150-129C>T,\N,\N,11/30,Benign,\N,intron_variant,0.1,0.0068,1KG_AFR_AF,OPA1
609336,3:193360448:C>G,NM_130837.2:c.1150-106C>G,\N,\N,11/30,Unknown significance,\N,intron_variant,3.202,\N,\N,OPA1
609337,3:193360460:CA>C,NM_130837.2:c.1150-92del,\N,\N,11/30,Unknown significance,\N,intron_variant,6.321,\N,\N,OPA1
609338,3:193360486:A>G,NM_130837.2:c.1150-68A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,0.201,\N,\N,OPA1
609339,3:193360489:C>A,NM_130837.2:c.1150-65C>A,\N,\N,11/30,Unknown significance,\N,intron_variant,2.053,\N,\N,OPA1
609340,3:193360506:T>C,NM_130837.2:c.1150-48T>C,\N,\N,11/30,Unknown significance,\N,intron_variant,2.614,0.0000149903,EXAC_NFE_AF,OPA1
609341,3:193360507:A>G,NM_130837.2:c.1150-47A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,1.507,0.000115687,EXAC_EAS_AF,OPA1
609342,3:193360511:C>T,NM_130837.2:c.1150-43C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,1.055,0.0000995025,EXAC_AFR_AF,OPA1
609343,3:193360514:A>G,NM_130837.2:c.1150-40A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,1.84,0.000116279,EVS_EA_AF,OPA1
609344,3:193360520:A>G,NM_130837.2:c.1150-34A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,4.9,0.0000605767,EXAC_SAS_AF,OPA1
609345,3:193360522:A>G,NM_130837.2:c.1150-32A>G,\N,\N,11/30,Unknown significance,\N,intron_variant,7.76,0.000453926,EVS_AA_AF,OPA1
609346,3:193360524:C>T,NM_130837.2:c.1150-30C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,8.584,0.004,1KG_EAS_AF,OPA1
609347,3:193360534:C>T,NM_130837.2:c.1150-20C>T,\N,\N,11/30,Unknown significance,\N,intron_variant,10.93,\N,\N,OPA1
609348,3:193360549:A>G,NM_130837.2:c.1150-5A>G,\N,\N,11/30,Unknown significance,\N,splice_region_variant&intron_variant,10.57,0.000060562,EXAC_SAS_AF,OPA1
609349,3:193360552:A>G,NM_130837.2:c.1150-2A>G,\N,\N,11/30,Pathogenic,Optic atrophy 1,splice_acceptor_variant,25.5,\N,\N,OPA1
609350,3:193360553:G>A,NM_130837.2:c.1150-1G>A,\N,\N,11/30,Pathogenic,Optic atrophy 1,splice_acceptor_variant,26.9,\N,\N,OPA1
609351,3:193360557:ACT>A,NM_130837.2:c.1156_1157del,NP_570850.2:p.Leu386GlufsTer2,12/31,\N,Pathogenic,Optic atrophy,frameshift_variant,35,\N,\N,OPA1
609352,3:193360558:C>G,NM_130837.2:c.1154C>G,NP_570850.2:p.Thr385Ser,12/31,\N,Pathogenic,Optic atrophy,missense_variant,29.8,\N,\N,OPA1
609353,3:193360561:T>C,NM_130837.2:c.1157T>C,NP_570850.2:p.Leu386Pro,12/31,\N,Likely pathogenic,Optic atrophy 1,missense_variant,29.7,\N,\N,OPA1
609354,3:193360569:G>A,NM_130837.2:c.1165G>A,NP_570850.2:p.Gly389Ser,12/31,\N,Unknown significance,\N,missense_variant,33,0.0000863856,EXAC_AMR_AF,OPA1
609355,3:193360570:G>A,NM_130837.2:c.1166G>A,NP_570850.2:p.Gly389Asp,12/31,\N,Unknown significance,\N,missense_variant,33,\N,\N,OPA1
609356,3:193360571:T>C,NM_130837.2:c.1167T>C,NP_570850.2:p.Gly389=,12/31,\N,Unknown significance,\N,synonymous_variant,6.19,0.0000149844,EXAC_NFE_AF,OPA1
609357,3:193360579:A>C,NM_130837.2:c.1175A>C,NP_570850.2:p.His392Pro,12/31,\N,Unknown significance,\N,missense_variant,27.5,0.000060562,EXAC_SAS_AF,OPA1
609358,3:193360580:T>C,NM_130837.2:c.1176T>C,NP_570850.2:p.His392=,12/31,\N,Unknown significance,\N,synonymous_variant,2.891,0.000116279,EVS_EA_AF,OPA1
609359,3:193360584:GC>G,NM_130837.2:c.1183del,NP_570850.2:p.Leu395TyrfsTer20,12/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,35,\N,\N,OPA1
609360,3:193360597:A>C,NM_130837.2:c.1193A>C,NP_570850.2:p.Asp398Ala,12/31,\N,Likely pathogenic,\N,missense_variant,27.5,0.00220264,EXAC_OTH_AF,OPA1
609361,3:193360605:C>T,NM_130837.2:c.1201C>T,NP_570850.2:p.Arg401Trp,12/31,\N,Unknown significance,\N,missense_variant,35,0.0000149862,EXAC_NFE_AF,OPA1
609362,3:193360608:G>T,NM_130837.2:c.1204G>T,NP_570850.2:p.Glu402Ter,12/31,\N,Pathogenic,Optic atrophy 1,stop_gained,42,\N,\N,OPA1
609363,3:193360617:C>G,NM_130837.2:c.1213C>G,NP_570850.2:p.Leu405Val,12/31,\N,Unknown significance,\N,missense_variant,27.9,0.000014988,EXAC_NFE_AF,OPA1
609364,3:193360623:AAAG>A,NM_130837.2:c.1227_1229del,NP_570850.2:p.Glu409del,12/31,\N,Unknown significance,\N,inframe_deletion,20.2,0.000121124,EXAC_SAS_AF,OPA1
609365,3:193360629:G>C,NM_130837.2:c.1225G>C,NP_570850.2:p.Glu409Gln,12/31,\N,Unknown significance,\N,missense_variant,22.9,0.0000975039,EXAC_AFR_AF,OPA1
609366,3:193360635:G>T,NM_130837.2:c.1230+1G>T,\N,\N,12/30,Pathogenic,Dominant hereditary optic atrophy; Optic Atrophy Type 1,splice_donor_variant,26.1,\N,\N,OPA1
609367,3:193360635:G>A,NM_130837.2:c.1230+1G>A,\N,\N,12/30,Pathogenic,Optic atrophy 1,splice_donor_variant,27.4,\N,\N,OPA1
609368,3:193360636:T>C,NM_130837.2:c.1230+2T>C,\N,\N,12/30,Pathogenic,Optic atrophy 1,splice_donor_variant,25.2,\N,\N,OPA1
609369,3:193360637:A>C,NM_130837.2:c.1230+3A>C,\N,\N,12/30,Pathogenic,Optic atrophy 1,splice_region_variant&intron_variant,13.51,\N,\N,OPA1
609370,3:193360638:A>G,NM_130837.2:c.1230+4A>G,\N,\N,12/30,Unknown significance,\N,splice_region_variant&intron_variant,16.68,\N,\N,OPA1
609371,3:193360639:G>A,NM_130837.2:c.1230+5G>A,\N,\N,12/30,Pathogenic,Optic atrophy,splice_region_variant&intron_variant,18.72,\N,\N,OPA1
609372,3:193360642:A>G,NM_130837.2:c.1230+8A>G,\N,\N,12/30,Unknown significance,\N,splice_region_variant&intron_variant,9.476,0.0000150015,EXAC_NFE_AF,OPA1
609373,3:193360653:A>AG,NM_130837.2:c.1230+21dup,\N,\N,12/30,Unknown significance,\N,intron_variant,7.856,0.0000150119,EXAC_NFE_AF,OPA1
609374,3:193360660:T>TA,NM_130837.2:c.1230+27dup,\N,\N,12/30,Unknown significance,\N,intron_variant,9.923,0.000060562,EXAC_SAS_AF,OPA1
609375,3:193360661:A>G,NM_130837.2:c.1230+27A>G,\N,\N,12/30,Unknown significance,\N,intron_variant,10.28,0.0000150186,EXAC_NFE_AF,OPA1
609376,3:193360673:A>G,NM_130837.2:c.1230+39A>G,\N,\N,12/30,Unknown significance,\N,intron_variant,6.328,\N,\N,OPA1
609377,3:193360677:C>A,NM_130837.2:c.1230+43C>A,\N,\N,12/30,Unknown significance,\N,intron_variant,5.143,0.0000150435,EXAC_NFE_AF,OPA1
609378,3:193360678:C>T,NM_130837.2:c.1230+44C>T,\N,\N,12/30,Unknown significance,\N,intron_variant,0.907,0.0000605694,EXAC_SAS_AF,OPA1
609379,3:193360691:T>C,NM_130837.2:c.1230+57T>C,\N,\N,12/30,Unknown significance,\N,intron_variant,2.295,\N,\N,OPA1
609380,3:193360692:A>G,NM_130837.2:c.1230+58A>G,\N,\N,12/30,Unknown significance,\N,intron_variant,3.375,0.001,1KG_SAS_AF,OPA1
609381,3:193360711:T>G,NM_130837.2:c.1231-53T>G,\N,\N,12/30,Benign,\N,intron_variant,15.16,0.0257,1KG_AFR_AF,OPA1
609382,3:193360716:G>C,NM_130837.2:c.1231-48G>C,\N,\N,12/30,Unknown significance,\N,intron_variant,11.09,0.000015345,EXAC_NFE_AF,OPA1
609383,3:193360721:AAGATTTTCTT>A,NM_130837.2:c.1231-30_1231-21del,\N,\N,12/30,Unknown significance,\N,intron_variant,10.74,0.000457178,EXAC_FIN_AF,OPA1
609384,3:193360724:A>G,NM_130837.2:c.1231-40A>G,\N,\N,12/30,Unknown significance,\N,intron_variant,9.091,0.0000154031,EXAC_NFE_AF,OPA1
609385,3:193360738:T>TC,NM_130837.2:c.1231-25dup,\N,\N,12/30,Unknown significance,\N,intron_variant,10.91,0.0000153243,EXAC_NFE_AF,OPA1
609386,3:193360739:C>T,NM_130837.2:c.1231-25C>T,\N,\N,12/30,Unknown significance,\N,intron_variant,11.98,0.0000612295,EXAC_SAS_AF,OPA1
609387,3:193360748:TTG>T,NM_130837.2:c.1231-12_1231-11del,\N,\N,12/30,Unknown significance,\N,intron_variant,13.31,0.000101937,EXAC_AFR_AF,OPA1
609388,3:193360749:T>C,NM_130837.2:c.1231-15T>C,\N,\N,12/30,Unknown significance,\N,intron_variant,13.02,0.000101874,EXAC_AFR_AF,OPA1
609389,3:193360759:A>G,NM_130837.2:c.1231-5A>G,\N,\N,12/30,Unknown significance,\N,splice_region_variant&intron_variant,10.55,0.0000152355,EXAC_NFE_AF,OPA1
609390,3:193360764:C>CTT,NM_130837.2:c.1232_1233dup,NP_570850.2:p.Ala412LeufsTer4,13/31,\N,Pathogenic,Optic atrophy & deafness,frameshift_variant&splice_region_variant,35,\N,\N,OPA1
609391,3:193360767:G>A,NM_015560.2:c.1069G>A,NP_056375.2:p.Ala357Thr,11/29,\N,Pathogenic,Optic atrophy 1,missense_variant,23.5,0.002,1KG_EAS_AF,OPA1
609392,3:193360769:A>G,NM_130837.2:c.1236A>G,NP_570850.2:p.Ala412=,13/31,\N,Benign,\N,synonymous_variant,11.45,0.00672646,EXAC_OTH_AF,OPA1
609393,3:193360772:A>G,NM_130837.2:c.1239A>G,NP_570850.2:p.Ala413=,13/31,\N,Pathogenic,Optic atrophy & epilepsy,synonymous_variant,12.2,\N,\N,OPA1
609394,3:193360777:G>C,NM_130837.2:c.1244G>C,NP_570850.2:p.Arg415Thr,13/31,\N,Unknown significance,\N,missense_variant,31,0.0000151888,EXAC_NFE_AF,OPA1
609395,3:193360780:A>G,NM_130837.2:c.1247A>G,NP_570850.2:p.His416Arg,13/31,\N,Unknown significance,\N,missense_variant,6.134,0.000226963,EVS_AA_AF,OPA1
609396,3:193360781:T>A,NM_130837.2:c.1248T>A,NP_570850.2:p.His416Gln,13/31,\N,Unknown significance,\N,missense_variant,21.7,0.000226963,EVS_AA_AF,OPA1
609397,3:193360782:G>T,NM_130837.2:c.1249G>T,NP_570850.2:p.Glu417Ter,13/31,\N,Pathogenic,Optic atrophy 1,stop_gained,45,\N,\N,OPA1
609398,3:193360785:A>C,NM_130837.2:c.1252A>C,NP_570850.2:p.Ile418Leu,13/31,\N,Unknown significance,\N,missense_variant,24.1,0.0000151874,EXAC_NFE_AF,OPA1
609399,3:193360794:C>T,NM_130837.2:c.1261C>T,NP_570850.2:p.Arg421Ter,13/31,\N,Pathogenic,Optic atrophy 1,stop_gained,40,\N,\N,OPA1
609400,3:193360795:G>A,NM_130837.2:c.1262G>A,NP_570850.2:p.Arg421Gln,13/31,\N,Unknown significance,\N,missense_variant,35,\N,\N,OPA1
609401,3:193360799:GA>G,NM_130837.2:c.1267del,NP_570850.2:p.Arg423GlyfsTer4,13/31,\N,Pathogenic,Optic atrophy,frameshift_variant,32,\N,\N,OPA1
609402,3:193360809:G>A,NM_130837.2:c.1276G>A,NP_570850.2:p.Val426Met,13/31,\N,Unknown significance,\N,missense_variant,31,0.0000152541,EXAC_NFE_AF,OPA1
609403,3:193360812:A>AGGT,NM_130837.2:c.1279_1280insGGT,NP_570850.2:p.Lys427delinsArgTer,13/31,\N,Unknown significance,\N,stop_gained&protein_altering_variant,37,\N,\N,OPA1
609404,3:193360814:A>AT,NM_130837.2:c.1281_1282insT,NP_570850.2:p.Glu428Ter,13/31,\N,Unknown significance,\N,frameshift_variant,35,\N,\N,OPA1
609405,3:193360818:G>C,NM_130837.2:c.1285G>C,NP_570850.2:p.Gly429Arg,13/31,\N,Unknown significance,\N,missense_variant,32,0.0000153135,EXAC_NFE_AF,OPA1
609406,3:193360819:G>A,NM_130837.2:c.1286G>A,NP_570850.2:p.Gly429Asp,13/31,\N,Unknown significance,\N,missense_variant,32,0.000123594,EXAC_SAS_AF,OPA1
609407,3:193360819:G>C,NM_130837.2:c.1286G>C,NP_570850.2:p.Gly429Ala,13/31,\N,Unknown significance,\N,missense_variant,28.2,0.0000617971,EXAC_SAS_AF,OPA1
609408,3:193360824:A>G,NM_130837.2:c.1291A>G,NP_570850.2:p.Thr431Ala,13/31,\N,Pathogenic,Optic atrophy 1,missense_variant,28.2,\N,\N,OPA1
609409,3:193360826:C>T,NM_130837.2:c.1293C>T,NP_570850.2:p.Thr431=,13/31,\N,Unknown significance,\N,synonymous_variant,16.53,0.000793493,EXAC_AFR_AF,OPA1
609410,3:193360827:G>A,NM_130837.2:c.1294G>A,NP_570850.2:p.Val432Ile,13/31,\N,Pathogenic,Optic atrophy+ Glaucoma,missense_variant,26.8,0.00011854,EXAC_EAS_AF,OPA1
609411,3:193360832:C>T,NM_130837.2:c.1299C>T,NP_570850.2:p.Ser433=,13/31,\N,Unknown significance,\N,synonymous_variant,16.03,0.0000998403,EXAC_AFR_AF,OPA1
609412,3:193360833:C>T,NM_130837.2:c.1300C>T,NP_570850.2:p.Pro434Ser,13/31,\N,Unknown significance,\N,missense_variant,14.11,0.0000155275,EXAC_NFE_AF,OPA1
609413,3:193360835:T>G,NM_130837.2:c.1302T>G,NP_570850.2:p.Pro434=,13/31,\N,Benign,\N,synonymous_variant,10.6,0.00113122,EXAC_OTH_AF,OPA1
609414,3:193360837:A>AG,NM_130837.2:c.1305+1dup,\N,13/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant&splice_region_variant,35,\N,\N,OPA1
609415,3:193360838:G>A,NM_130837.2:c.1305G>A,NP_570850.2:p.Glu435=,13/31,\N,Likely pathogenic,Optic atrophy 1,splice_region_variant&synonymous_variant,17.2,\N,\N,OPA1
609416,3:193360839:G>C,NM_130837.2:c.1305+1G>C,\N,\N,13/30,Unknown significance,\N,splice_donor_variant,25.7,0.000100806,EXAC_AFR_AF,OPA1
609417,3:193360839:G>A,NM_130837.2:c.1305+1G>A,\N,\N,13/30,Pathogenic,Optic atrophy 1,splice_donor_variant,27,\N,\N,OPA1
609418,3:193360839:G>T,NM_130837.2:c.1305+1G>T,\N,\N,13/30,Pathogenic,Optic atrophy,splice_donor_variant,25.8,\N,\N,OPA1
609419,3:193360843:G>C,NM_130837.2:c.1305+5G>C,\N,\N,13/30,Pathogenic,Optic atrophy 1,splice_region_variant&intron_variant,7.353,\N,\N,OPA1
609420,3:193360846:T>C,NM_130837.2:c.1305+8T>C,\N,\N,13/30,Unknown significance,\N,splice_region_variant&intron_variant,2.207,0.0000640615,EXAC_SAS_AF,OPA1
609421,3:193360859:C>G,NM_130837.2:c.1305+21C>G,\N,\N,13/30,Unknown significance,\N,intron_variant,3.509,0.000226963,EVS_AA_AF,OPA1
609422,3:193360865:C>T,NM_130837.2:c.1305+27C>T,\N,\N,13/30,Unknown significance,\N,intron_variant,2.711,0.000663922,EXAC_SAS_AF,OPA1
609423,3:193360866:G>A,NM_130837.2:c.1305+28G>A,\N,\N,13/30,Unknown significance,\N,intron_variant,1.163,0.000133156,EXAC_SAS_AF,OPA1
609424,3:193360872:T>C,NM_130837.2:c.1305+34T>C,\N,\N,13/30,Unknown significance,\N,intron_variant,4.831,0.000135796,EXAC_EAS_AF,OPA1
609425,3:193360873:G>A,NM_130837.2:c.1305+35G>A,\N,\N,13/30,Unknown significance,\N,intron_variant,6.668,0.0000681385,EXAC_SAS_AF,OPA1
609426,3:193360878:T>C,NM_130837.2:c.1305+40T>C,\N,\N,13/30,Unknown significance,\N,intron_variant,1.359,0.0000176348,EXAC_NFE_AF,OPA1
609427,3:193360948:T>C,NM_130837.2:c.1305+110T>C,\N,\N,13/30,Unknown significance,\N,intron_variant,3.78,0.001,1KG_SAS_AF,OPA1
609428,3:193360957:T>TA,NM_130837.2:c.1305+128dup,\N,\N,13/30,Benign,\N,intron_variant,0.949,0.1036,1KG_AFR_AF,OPA1
609429,3:193360957:TA>T,NM_130837.2:c.1305+128del,\N,\N,13/30,Benign,\N,intron_variant,0.677,0.0388,1KG_EUR_AF,OPA1
609430,3:193360959:A>T,NM_130837.2:c.1305+121A>T,\N,\N,13/30,Unknown significance,\N,intron_variant,0.461,0.001,1KG_EAS_AF,OPA1
609431,3:193360968:C>T,NM_130837.2:c.1305+130C>T,\N,\N,13/30,Benign,\N,intron_variant,5.048,0.0109,1KG_EAS_AF,OPA1
609432,3:193361001:A>G,NM_130837.2:c.1306-161A>G,\N,\N,13/30,Benign,\N,intron_variant,8.74,0.0149,1KG_EAS_AF,OPA1
609433,3:193361011:C>G,NM_130837.2:c.1306-151C>G,\N,\N,13/30,Unknown significance,\N,intron_variant,9.707,\N,\N,OPA1
609434,3:193361036:A>C,NM_130837.2:c.1306-126A>C,\N,\N,13/30,Unknown significance,\N,intron_variant,1.786,0.001,1KG_EAS_AF,OPA1
609435,3:193361042:G>A,NM_130837.2:c.1306-120G>A,\N,\N,13/30,Benign,\N,intron_variant,0.537,0.0079,1KG_EAS_AF,OPA1
609436,3:193361048:G>A,NM_130837.2:c.1306-114G>A,\N,\N,13/30,Benign,\N,intron_variant,2.324,0.0109,1KG_EAS_AF,OPA1
609437,3:193361053:A>T,NM_130837.2:c.1306-109A>T,\N,\N,13/30,Benign,\N,intron_variant,2.483,0.0272,1KG_AFR_AF,OPA1
609438,3:193361057:G>A,NM_130837.2:c.1306-105G>A,\N,\N,13/30,Unknown significance,\N,intron_variant,4.77,0.001,1KG_SAS_AF,OPA1
609439,3:193361073:G>A,NM_130837.2:c.1306-89G>A,\N,\N,13/30,Unknown significance,\N,intron_variant,5.017,\N,\N,OPA1
609440,3:193361073:G>T,NM_130837.2:c.1306-89G>T,\N,\N,13/30,Unknown significance,\N,intron_variant,2.372,0.0014,1KG_AMR_AF,OPA1
609441,3:193361103:A>T,NM_130837.2:c.1306-59A>T,\N,\N,13/30,Unknown significance,\N,intron_variant,1.929,0.001,1KG_SAS_AF,OPA1
609442,3:193361107:T>A,NM_130837.2:c.1306-55T>A,\N,\N,13/30,Benign,\N,intron_variant,5.242,0.007,1KG_EUR_AF,OPA1
609443,3:193361110:A>G,NM_130837.2:c.1306-52A>G,\N,\N,13/30,Unknown significance,\N,intron_variant,1.135,0.001,1KG_EUR_AF,OPA1
609444,3:193361113:A>G,NM_130837.2:c.1306-49A>G,\N,\N,13/30,Unknown significance,\N,intron_variant,4.516,0.000103584,EXAC_AFR_AF,OPA1
609445,3:193361116:T>C,NM_130837.2:c.1306-46T>C,\N,\N,13/30,Unknown significance,\N,intron_variant,4.168,0.000356888,EXAC_EAS_AF,OPA1
609446,3:193361117:C>T,NM_130837.2:c.1306-45C>T,\N,\N,13/30,Unknown significance,\N,intron_variant,2.446,0.000791814,EXAC_SAS_AF,OPA1
609447,3:193361118:C>T,NM_130837.2:c.1306-44C>T,\N,\N,13/30,Unknown significance,\N,intron_variant,4.085,0.00010352,EXAC_AFR_AF,OPA1
609448,3:193361120:C>A,NM_130837.2:c.1306-42C>A,\N,\N,13/30,Unknown significance,\N,intron_variant,2.451,0.0000152751,EXAC_NFE_AF,OPA1
609449,3:193361121:C>T,NM_130837.2:c.1306-41C>T,\N,\N,13/30,Unknown significance,\N,intron_variant,2.509,0.001,1KG_EUR_AF,OPA1
609450,3:193361124:A>G,NM_130837.2:c.1306-38A>G,\N,\N,13/30,Unknown significance,\N,intron_variant,4.171,0.000233372,EVS_EA_AF,OPA1
609451,3:193361124:A>T,NM_130837.2:c.1306-38A>T,\N,\N,13/30,Unknown significance,\N,intron_variant,3.249,0.0000152546,EXAC_NFE_AF,OPA1
609452,3:193361126:C>T,NM_130837.2:c.1306-36C>T,\N,\N,13/30,Unknown significance,\N,intron_variant,2.712,0.0000152499,EXAC_NFE_AF,OPA1
609453,3:193361131:G>A,NM_130837.2:c.1306-31G>A,\N,\N,13/30,Unknown significance,\N,intron_variant,0.291,0.001,1KG_SAS_AF,OPA1
609454,3:193361142:T>G,NM_130837.2:c.1306-20T>G,\N,\N,13/30,Unknown significance,\N,intron_variant,0.094,\N,\N,OPA1
609455,3:193361146:T>C,NM_130837.2:c.1306-16T>C,\N,\N,13/30,Unknown significance,\N,intron_variant,2.485,0.0000606722,EXAC_SAS_AF,OPA1
609456,3:193361153:C>T,NM_130837.2:c.1306-9C>T,\N,\N,13/30,Unknown significance,\N,intron_variant,10.41,0.000581395,EXAC_EAS_AF,OPA1
609457,3:193361156:G>A,NM_130837.2:c.1306-6G>A,\N,\N,13/30,Unknown significance,\N,splice_region_variant&intron_variant,10.61,0.0000606061,EXAC_SAS_AF,OPA1
609458,3:193361167:A>G,NM_130837.2:c.1311A>G,NP_570850.2:p.Ile437Met,14/31,\N,Likely Benign,\N,missense_variant,24.4,0.00221239,EXAC_OTH_AF,OPA1
609459,3:193361170:C>T,NM_130837.2:c.1314C>T,NP_570850.2:p.Ser438=,14/31,\N,Unknown significance,\N,synonymous_variant,15.1,0.000015077,EXAC_NFE_AF,OPA1
609460,3:193361172:T>TA,NM_130837.2:c.1319dup,NP_570850.2:p.Asn440LysfsTer14,14/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,35,\N,\N,OPA1
609461,3:193361172:TAA>T,NM_130837.2:c.1318_1319del,NP_570850.2:p.Asn440CysfsTer13,14/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,35,\N,\N,OPA1
609462,3:193361173:A>C,NM_130837.2:c.1317A>C,NP_570850.2:p.Leu439Phe,14/31,\N,Pathogenic,Optic atrophy 1,missense_variant,26.6,\N,\N,OPA1
609463,3:193361175:A>G,NM_130837.2:c.1319A>G,NP_570850.2:p.Asn440Ser,14/31,\N,Unknown significance,\N,missense_variant,10.79,0.00010008,EXAC_AFR_AF,OPA1
609464,3:193361176:T>C,NM_130837.2:c.1320T>C,NP_570850.2:p.Asn440=,14/31,\N,Unknown significance,\N,synonymous_variant,5.919,0.000242277,EXAC_SAS_AF,OPA1
609465,3:193361191:A>G,NM_130837.2:c.1335A>G,NP_570850.2:p.Gly445=,14/31,\N,Unknown significance,\N,synonymous_variant,9.299,0.0000865052,EXAC_AMR_AF,OPA1
609466,3:193361196:A>G,NM_130834.2:c.1229A>G,NP_570847.2:p.Gln410Arg,13/30,\N,Unknown significance,\N,missense_variant,18.41,0.0000605767,EXAC_SAS_AF,OPA1
609467,3:193361198:A>C,NM_130837.2:c.1342A>C,NP_570850.2:p.Arg448=,14/31,\N,Benign,\N,synonymous_variant,1.811,0.0223528,EXAC_SAS_AF,OPA1
609468,3:193361201:A>G,NM_130837.2:c.1345A>G,NP_570850.2:p.Met449Val,14/31,\N,Unknown significance,\N,missense_variant,25.3,0.0000150466,EXAC_NFE_AF,OPA1
609469,3:193361203:G>A,NM_130837.2:c.1347G>A,NP_570850.2:p.Met449Ile,14/31,\N,Unknown significance,\N,missense_variant,29.1,0.000226963,EVS_AA_AF,OPA1
609470,3:193361208:T>A,NM_130837.2:c.1352T>A,NP_570850.2:p.Leu451His,14/31,\N,Pathogenic,\N,missense_variant,29.8,\N,\N,OPA1
609471,3:193361208:T>G,NM_130837.2:c.1352T>G,NP_570850.2:p.Leu451Arg,14/31,\N,Pathogenic,Optic atrophy 1,missense_variant,28.4,\N,\N,OPA1
609472,3:193361208:T>C,NM_130837.2:c.1352T>C,NP_570850.2:p.Leu451Pro,14/31,\N,Pathogenic,Optic atrophy 1,missense_variant,28.7,\N,\N,OPA1
609473,3:193361219:C>G,NM_130837.2:c.1363C>G,NP_570850.2:p.Pro455Ala,14/31,\N,Pathogenic,Optic atrophy,missense_variant,28.4,\N,\N,OPA1
609474,3:193361219:C>T,NM_130837.2:c.1363C>T,NP_570850.2:p.Pro455Ser,14/31,\N,Pathogenic,Optic atrophy 1,missense_variant,33,\N,\N,OPA1
609475,3:193361220:C>T,NM_130837.2:c.1364C>T,NP_570850.2:p.Pro455Leu,14/31,\N,Pathogenic,Optic atrophy 1,missense_variant,34,\N,\N,OPA1
609476,3:193361222:G>C,NM_130837.2:c.1366G>C,NP_570850.2:p.Gly456Arg,14/31,\N,Pathogenic,Optic atrophy,missense_variant,32,\N,\N,OPA1
609477,3:193361223:G>A,NM_130837.2:c.1367G>A,NP_570850.2:p.Gly456Asp,14/31,\N,Pathogenic,Optic atrophy 1,missense_variant,33,\N,\N,OPA1
609478,3:193361225:G>A,NM_130837.2:c.1369G>A,NP_570850.2:p.Val457Met,14/31,\N,Pathogenic,Behr syndrome| early-onset,missense_variant,25.3,\N,\N,OPA1
609479,3:193361229:T>C,NM_130837.2:c.1373T>C,NP_570850.2:p.Ile458Thr,14/31,\N,Likely pathogenic,\N,missense_variant,27.9,\N,\N,OPA1
609480,3:193361229:TTAATG>T,NM_130837.2:c.1377_1377+4del,\N,14/31,14/30,Pathogenic,Optic atrophy 1,splice_donor_variant&coding_sequence_variant,35,\N,\N,OPA1
609481,3:193361234:G>A,NM_130837.2:c.1377+1G>A,\N,\N,14/30,Pathogenic,Optic atrophy 1,splice_donor_variant,27.8,\N,\N,OPA1
609482,3:193361234:G>GT,NM_130837.2:c.1377+2dup,\N,\N,14/30,Pathogenic,Optic atrophy,splice_donor_variant,26.5,\N,\N,OPA1
609483,3:193361234:G>T,NM_130837.2:c.1377+1G>T,\N,\N,14/30,Pathogenic,Optic atrophy 1,splice_donor_variant,26.3,\N,\N,OPA1
609484,3:193361235:T>G,NM_130837.2:c.1377+2T>G,\N,\N,14/30,Pathogenic,Optic atrophy 1,splice_donor_variant,25.8,\N,\N,OPA1
609485,3:193361236:A>T,NM_130837.2:c.1377+3A>T,\N,\N,14/30,Pathogenic,Optic atrophy 1,splice_region_variant&intron_variant,13.78,\N,\N,OPA1
609486,3:193361238:G>T,NM_130837.2:c.1377+5G>T,\N,\N,14/30,Pathogenic,\N,splice_region_variant&intron_variant,17.22,\N,\N,OPA1
609487,3:193361238:GT>TC,NM_130837.2:c.1377+5_1377+6delinsTC,\N,\N,14/30,Unknown significance,\N,splice_region_variant&intron_variant,\N,\N,\N,OPA1
609488,3:193361238:G>C,NM_130837.2:c.1377+5G>C,\N,\N,14/30,Pathogenic,Optic atrophy 1,splice_region_variant&intron_variant,16.69,\N,\N,OPA1
609489,3:193361242:A>G,NM_130837.2:c.1377+9A>G,\N,\N,14/30,Unknown significance,\N,intron_variant,13.9,0.000349813,EXAC_EAS_AF,OPA1
609490,3:193361243:T>C,NM_130837.2:c.1377+10T>C,\N,\N,14/30,Unknown significance,\N,intron_variant,13.74,0.00424978,EXAC_AMR_AF,OPA1
609491,3:193361251:A>G,NM_130837.2:c.1377+18A>G,\N,\N,14/30,Unknown significance,\N,intron_variant,11.78,0.0000150807,EXAC_NFE_AF,OPA1
609492,3:193361251:A>T,NM_130837.2:c.1377+18A>T,\N,\N,14/30,Unknown significance,\N,intron_variant,10.98,0.0014,1KG_AMR_AF,OPA1
609493,3:193361252:T>C,NM_130837.2:c.1377+19T>C,\N,\N,14/30,Unknown significance,\N,intron_variant,10.91,0.000015083,EXAC_NFE_AF,OPA1
609494,3:193361263:T>G,NM_130837.2:c.1377+30T>G,\N,\N,14/30,Unknown significance,\N,intron_variant,8.867,0.0000990295,EXAC_AFR_AF,OPA1
609495,3:193361271:A>T,NM_130837.2:c.1377+38A>T,\N,\N,14/30,Benign,\N,intron_variant,5.336,0.0162248,EXAC_AFR_AF,OPA1
609496,3:193361272:T>C,NM_130837.2:c.1377+39T>C,\N,\N,14/30,Unknown significance,\N,intron_variant,6.595,0.000030216,EXAC_NFE_AF,OPA1
609497,3:193361283:A>C,NM_130837.2:c.1378-34A>C,\N,\N,14/30,Unknown significance,\N,intron_variant,5.138,0.000151837,EXAC_FIN_AF,OPA1
609498,3:193361285:T>C,NM_130837.2:c.1378-32T>C,\N,\N,14/30,Unknown significance,\N,intron_variant,9.216,0.00267347,EXAC_SAS_AF,OPA1
609499,3:193361290:A>T,NM_130837.2:c.1378-27A>T,\N,\N,14/30,Unknown significance,\N,intron_variant,14.27,0.000117398,EXAC_EAS_AF,OPA1
609500,3:193361291:T>G,NM_130837.2:c.1378-26T>G,\N,\N,14/30,Unknown significance,\N,intron_variant,16.99,0.0000150962,EXAC_NFE_AF,OPA1
609501,3:193361292:G>C,NM_130837.2:c.1378-25G>C,\N,\N,14/30,Benign,\N,intron_variant,13.57,0.0132723,EXAC_EAS_AF,OPA1
609502,3:193361313:T>C,NM_130837.2:c.1378-4T>C,\N,\N,14/30,Unknown significance,\N,splice_region_variant&intron_variant,10.76,0.0000150639,EXAC_NFE_AF,OPA1
609503,3:193361319:T>C,NM_130837.2:c.1380T>C,NP_570850.2:p.Thr460=,15/31,\N,Unknown significance,\N,splice_region_variant&synonymous_variant,12.36,0.0000451236,EXAC_NFE_AF,OPA1
609504,3:193361330:G>A,NM_015560.2:c.1226G>A,NP_056375.2:p.Gly409Asp,13/29,\N,Unknown significance,\N,missense_variant,22.3,0.0000150322,EXAC_NFE_AF,OPA1
609505,3:193361336:C>G,NM_130837.2:c.1397C>G,NP_570850.2:p.Ala466Gly,15/31,\N,Unknown significance,\N,missense_variant,33,0.000116117,EXAC_EAS_AF,OPA1
609506,3:193361354:CTAT>C,NM_130837.2:c.1417_1419del,NP_570850.2:p.Ile473del,15/31,\N,Pathogenic,Optic atrophy 1,inframe_deletion,21.2,\N,\N,OPA1
609507,3:193361364:T>TATC,NM_130837.2:c.1427_1429dup,NP_570850.2:p.Ile476dup,15/31,\N,Pathogenic,Optic atrophy,inframe_insertion,19.09,\N,\N,OPA1
609508,3:193361380:A>T,NM_130834.2:c.1330A>T,NP_570847.2:p.Met444Leu,14/30,\N,Unknown significance,\N,missense_variant,24.2,0.000486855,EXAC_SAS_AF,OPA1
609509,3:193361383:C>A,NM_130837.2:c.1444C>A,NP_570850.2:p.Gln482Lys,15/31,\N,Unknown significance,\N,missense_variant,19.48,0.0000609088,EXAC_SAS_AF,OPA1
609510,3:193361383:C>T,NM_130837.2:c.1444C>T,NP_570850.2:p.Gln482Ter,15/31,\N,Pathogenic,Optic atrophy 1,stop_gained,40,\N,\N,OPA1
609511,3:193361385:GAATCCT>G,NM_130837.2:c.1450_1455del,NP_570850.2:p.Pro484_Asn485del,15/31,\N,Pathogenic,Optic atrophy 1,inframe_deletion,22.6,\N,\N,OPA1
609512,3:193361392:A>G,NM_130837.2:c.1453A>G,NP_570850.2:p.Asn485Asp,15/31,\N,Pathogenic,Optic atrophy 1,missense_variant,28.6,\N,\N,OPA1
609513,3:193361396:CCAT>C,NM_130837.2:c.1461_1463del,NP_570850.2:p.Ile488del,15/31,\N,Pathogenic,Optic atrophy 1,inframe_deletion,22.9,\N,\N,OPA1
609514,3:193361398:A>G,NM_130837.2:c.1459A>G,NP_570850.2:p.Ile487Val,15/31,\N,Pathogenic,Multiple mitochondrial DNA deletion disorder,missense_variant,26.8,\N,\N,OPA1
609515,3:193361404:CTG>C,NM_130837.2:c.1469_1470del,NP_570850.2:p.Cys490TyrfsTer9,15/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,35,\N,\N,OPA1
609516,3:193361405:T>G,NM_130837.2:c.1466T>G,NP_570850.2:p.Leu489Arg,15/31,\N,Pathogenic,Optic atrophy,missense_variant,32,\N,\N,OPA1
609517,3:193361408:G>A,NM_130837.2:c.1469G>A,NP_570850.2:p.Cys490Tyr,15/31,\N,Pathogenic,Optic atrophy,missense_variant,29.7,\N,\N,OPA1
609518,3:193361414:A>G,NM_130837.2:c.1475A>G,NP_570850.2:p.Gln492Arg,15/31,\N,Pathogenic,Optic atrophy & deafness,missense_variant&splice_region_variant,27.4,\N,\N,OPA1
609519,3:193361440:A>G,NM_130837.2:c.1477+24A>G,\N,\N,15/30,Unknown significance,\N,intron_variant,1.058,0.0000163377,EXAC_NFE_AF,OPA1
609520,3:193361441:T>G,NM_130837.2:c.1477+25T>G,\N,\N,15/30,Unknown significance,\N,intron_variant,3.382,0.0000163463,EXAC_NFE_AF,OPA1
609521,3:193361442:G>A,NM_130837.2:c.1477+26G>A,\N,\N,15/30,Unknown significance,\N,intron_variant,1.493,0.0000646329,EXAC_SAS_AF,OPA1
609522,3:193361448:A>G,NM_130837.2:c.1477+32A>G,\N,\N,15/30,Benign,\N,intron_variant,5.224,0.013,1KG_AMR_AF,OPA1
609523,3:193361449:T>C,NM_130837.2:c.1477+33T>C,\N,\N,15/30,Unknown significance,\N,intron_variant,4.177,0.0015,1KG_AFR_AF,OPA1
609524,3:193361450:A>G,NM_130837.2:c.1477+34A>G,\N,\N,15/30,Unknown significance,\N,intron_variant,1.965,0.0000166107,EXAC_NFE_AF,OPA1
609525,3:193361451:T>C,NM_130837.2:c.1477+35T>C,\N,\N,15/30,Unknown significance,\N,intron_variant,1.646,0.000129166,EXAC_EAS_AF,OPA1
609526,3:193361458:T>C,NM_130837.2:c.1477+42T>C,\N,\N,15/30,Unknown significance,\N,intron_variant,12.1,0.0000341845,EXAC_NFE_AF,OPA1
609527,3:193361463:T>A,NM_130837.2:c.1477+47T>A,\N,\N,15/30,Unknown significance,\N,intron_variant,14.53,\N,\N,OPA1
609528,3:193361464:A>G,NM_130837.2:c.1477+48A>G,\N,\N,15/30,Unknown significance,\N,intron_variant,14,\N,\N,OPA1
609529,3:193361468:A>G,NM_130837.2:c.1477+52A>G,\N,\N,15/30,Unknown significance,\N,intron_variant,12.34,0.003,1KG_EAS_AF,OPA1
609530,3:193361473:A>G,NM_130837.2:c.1477+57A>G,\N,\N,15/30,Unknown significance,\N,intron_variant,12.08,0.001,1KG_EAS_AF,OPA1
609531,3:193361476:T>C,NM_130837.2:c.1477+60T>C,\N,\N,15/30,Unknown significance,\N,intron_variant,6.722,0.0014,1KG_AMR_AF,OPA1
609532,3:193361491:T>A,NM_130837.2:c.1477+75T>A,\N,\N,15/30,Unknown significance,\N,intron_variant,3.367,0.0008,1KG_AFR_AF,OPA1
609533,3:193361538:G>A,NM_130837.2:c.1477+122G>A,\N,\N,15/30,Unknown significance,\N,intron_variant,0.077,0.0043,1KG_AMR_AF,OPA1
609534,3:193361617:C>T,NM_130837.2:c.1478-147C>T,\N,\N,15/30,Benign,\N,intron_variant,2.97,0.4265,1KG_AMR_AF,OPA1
609535,3:193361618:G>A,NM_130837.2:c.1478-146G>A,\N,\N,15/30,Unknown significance,\N,intron_variant,3.176,0.001,1KG_SAS_AF,OPA1
609536,3:193361621:T>G,NM_130837.2:c.1478-143T>G,\N,\N,15/30,Benign,\N,intron_variant,5.804,0.005,1KG_EAS_AF,OPA1
609537,3:193361623:G>A,NM_130837.2:c.1478-141G>A,\N,\N,15/30,Unknown significance,\N,intron_variant,3.051,\N,\N,OPA1
609538,3:193361630:T>G,NM_130837.2:c.1478-134T>G,\N,\N,15/30,Unknown significance,\N,intron_variant,4.003,\N,\N,OPA1
609539,3:193361644:C>T,NM_130837.2:c.1478-120C>T,\N,\N,15/30,Unknown significance,\N,intron_variant,2.554,0.001,1KG_EAS_AF,OPA1
609540,3:193361653:A>G,NM_130837.2:c.1478-111A>G,\N,\N,15/30,Unknown significance,\N,intron_variant,7.942,\N,\N,OPA1
609541,3:193361683:CAG>C,NM_130837.2:c.1478-80_1478-79del,\N,\N,15/30,Unknown significance,\N,intron_variant,8.095,0.0041,1KG_SAS_AF,OPA1
609542,3:193361713:G>C,NM_130837.2:c.1478-51G>C,\N,\N,15/30,Unknown significance,\N,intron_variant,0.098,0.0000160746,EXAC_NFE_AF,OPA1
609543,3:193361714:TC>T,NM_130837.2:c.1478-49del,\N,\N,15/30,Unknown significance,\N,intron_variant,2.79,\N,\N,OPA1
609544,3:193361722:A>G,NM_130837.2:c.1478-42A>G,\N,\N,15/30,Unknown significance,\N,intron_variant,4.492,0.0000160421,EXAC_NFE_AF,OPA1
609545,3:193361737:A>G,NM_130837.2:c.1478-27A>G,\N,\N,15/30,Unknown significance,\N,intron_variant,6.57,0.000177936,EXAC_AMR_AF,OPA1
609546,3:193361739:A>C,NM_130837.2:c.1478-25A>C,\N,\N,15/30,Unknown significance,\N,intron_variant,4.987,0.000102375,EXAC_AFR_AF,OPA1
609547,3:193361740:G>A,NM_130837.2:c.1478-24G>A,\N,\N,15/30,Unknown significance,\N,intron_variant,7.942,0.0000157649,EXAC_NFE_AF,OPA1
609548,3:193361742:G>C,NM_130837.2:c.1478-22G>C,\N,\N,15/30,Unknown significance,\N,intron_variant,5.787,0.00015706,EXAC_NFE_AF,OPA1
609549,3:193361744:C>G,NM_130837.2:c.1478-20C>G,\N,\N,15/30,Unknown significance,\N,intron_variant,5.23,\N,\N,OPA1
609550,3:193361744:C>T,NM_130837.2:c.1478-20C>T,\N,\N,15/30,Unknown significance,\N,intron_variant,6.584,0.0000619425,EXAC_SAS_AF,OPA1
609551,3:193361745:A>AT,NM_130837.2:c.1478-12dup,\N,\N,15/30,Unknown significance,\N,intron_variant,2.142,0.0000156348,EXAC_NFE_AF,OPA1
609552,3:193361752:T>A,NM_130837.2:c.1478-12T>A,\N,\N,15/30,Unknown significance,\N,intron_variant,0.995,0.0000877347,EXAC_AMR_AF,OPA1
609553,3:193361757:T>C,NM_130837.2:c.1478-7T>C,\N,\N,15/30,Unknown significance,\N,splice_region_variant&intron_variant,9.414,0.000262513,EXAC_AMR_AF,OPA1
609554,3:193361762:A>G,NM_130837.2:c.1478-2A>G,\N,\N,15/30,Pathogenic,Optic atrophy 1,splice_acceptor_variant,25.4,\N,\N,OPA1
609555,3:193361762:AGATG>A,NM_130837.2:c.1480_1483del,NP_570850.2:p.Gly494LeufsTer27,16/31,15/30,Pathogenic,Optic atrophy 1,splice_acceptor_variant&coding_sequence_variant,35,\N,\N,OPA1
609556,3:193361763:G>A,NM_130837.2:c.1478-1G>A,\N,\N,15/30,Pathogenic,Optic atrophy 1,splice_acceptor_variant,26.4,\N,\N,OPA1
609557,3:193361764:A>C,NM_130837.2:c.1478A>C,NP_570850.2:p.Asp493Ala,16/31,\N,Pathogenic,Optic atrophy,missense_variant&splice_region_variant,27.9,\N,\N,OPA1
609558,3:193361764:A>G,NM_130837.2:c.1478A>G,NP_570850.2:p.Asp493Gly,16/31,\N,Pathogenic,Optic atrophy 1,missense_variant&splice_region_variant,28.9,\N,\N,OPA1
609559,3:193361764:A>T,NM_130837.2:c.1478A>T,NP_570850.2:p.Asp493Val,16/31,\N,Pathogenic,Optic atrophy 1,missense_variant&splice_region_variant,28.2,\N,\N,OPA1
609560,3:193361767:G>T,NM_130837.2:c.1481G>T,NP_570850.2:p.Gly494Val,16/31,\N,Pathogenic,Optic atrophy 1,missense_variant,30,\N,\N,OPA1
609561,3:193361778:G>A,NM_130837.2:c.1492G>A,NP_570850.2:p.Ala498Thr,16/31,\N,Pathogenic,Optic atrophy| deafness & ataxia,missense_variant,33,\N,\N,OPA1
609562,3:193361785:G>A,NM_130837.2:c.1499G>A,NP_570850.2:p.Arg500His,16/31,\N,Pathogenic,Optic atrophy 1,missense_variant,34,\N,\N,OPA1
609563,3:193361796:AC>A,NM_130837.2:c.1511del,NP_570850.2:p.Thr504LysfsTer18,16/31,\N,Likely pathogenic,Optic Atrophy Type 1,frameshift_variant,\N,\N,\N,OPA1
609564,3:193361796:A>G,NM_130837.2:c.1510A>G,NP_570850.2:p.Thr504Ala,16/31,\N,Unknown significance,\N,missense_variant,24.7,0.000151332,EXAC_FIN_AF,OPA1
609565,3:193361796:A>AC,NM_130837.2:c.1511dup,NP_570850.2:p.Asp505ArgfsTer38,16/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,35,\N,\N,OPA1
609566,3:193361796:A>C,NM_130837.2:c.1510A>C,NP_570850.2:p.Thr504Pro,16/31,\N,Pathogenic,Optic atrophy| ataxia & neuropathy,missense_variant,28.1,\N,\N,OPA1
609567,3:193361797:C>G,NM_130837.2:c.1511C>G,NP_570850.2:p.Thr504Arg,16/31,\N,Pathogenic,Optic atrophy 1,missense_variant,29.2,\N,\N,OPA1
609568,3:193361799:G>C,NM_130837.2:c.1513G>C,NP_570850.2:p.Asp505His,16/31,\N,Unknown significance,\N,missense_variant,32,0.0000864753,EXAC_AMR_AF,OPA1
609569,3:193361800:A>G,NM_130837.2:c.1514A>G,NP_570850.2:p.Asp505Gly,16/31,\N,Unknown significance,\N,missense_variant,31,0.0000150038,EXAC_NFE_AF,OPA1
609570,3:193361801:CT>C,NM_130837.2:c.1517del,NP_570850.2:p.Leu506TrpfsTer16,16/31,\N,Pathogenic,Dominant hereditary optic atrophy,frameshift_variant,\N,\N,\N,OPA1
609571,3:193361801:C>T,NM_130837.2:c.1515C>T,NP_570850.2:p.Asp505=,16/31,\N,Unknown significance,\N,synonymous_variant,14.07,0.0000961538,EXAC_AFR_AF,OPA1
609572,3:193361803:TG>T,NM_130837.2:c.1519del,NP_570850.2:p.Val507SerfsTer15,16/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,32,\N,\N,OPA1
609573,3:193361804:G>C,NM_130837.2:c.1518G>C,NP_570850.2:p.Leu506Phe,16/31,\N,Unknown significance,\N,missense_variant,24.8,0.000015002,EXAC_NFE_AF,OPA1
609574,3:193361813:A>G,NM_130837.2:c.1527A>G,NP_570850.2:p.Gln509=,16/31,\N,Unknown significance,\N,synonymous_variant,4.715,0.0000961354,EXAC_AFR_AF,OPA1
609575,3:193361824:A>G,NM_130837.2:c.1538A>G,NP_570850.2:p.His513Arg,16/31,\N,Unknown significance,\N,missense_variant,15.73,0.0000605767,EXAC_SAS_AF,OPA1
609576,3:193361827:G>A,NM_130837.2:c.1541G>A,NP_570850.2:p.Gly514Glu,16/31,\N,Pathogenic,Optic atrophy,missense_variant,32,\N,\N,OPA1
609577,3:193361836:C>T,NM_130837.2:c.1550C>T,NP_570850.2:p.Thr517Ile,16/31,\N,Unknown significance,\N,missense_variant,33,0.0000605694,EXAC_SAS_AF,OPA1
609578,3:193361836:C>CCATATT,NM_130837.2:c.1552_1557dup,NP_570850.2:p.Ile518_Phe519dup,16/31,\N,Pathogenic,Optic atrophy 1,inframe_insertion,22.4,\N,\N,OPA1
609579,3:193361840:A>G,NM_130837.2:c.1554A>G,NP_570850.2:p.Ile518Met,16/31,\N,Unknown significance,\N,missense_variant,25.8,0.000121139,EXAC_SAS_AF,OPA1
609580,3:193361840:A>T,NM_130837.2:c.1554A>T,NP_570850.2:p.Ile518=,16/31,\N,Unknown significance,\N,synonymous_variant,2.796,0.0000149921,EXAC_NFE_AF,OPA1
609581,3:193361841:T>C,NM_015560.2:c.1390T>C,NP_056375.2:p.Phe464Leu,14/29,\N,Unknown significance,\N,missense_variant,25.5,0.0000149921,EXAC_NFE_AF,OPA1
609582,3:193361843:C>T,NM_130837.2:c.1557C>T,NP_570850.2:p.Phe519=,16/31,\N,Unknown significance,\N,synonymous_variant,18.17,0.0000864304,EXAC_AMR_AF,OPA1
609583,3:193361853:A>G,NM_130837.2:c.1567A>G,NP_570850.2:p.Lys523Glu,16/31,\N,Pathogenic,Optic atrophy 1,missense_variant,32,\N,\N,OPA1
609584,3:193361855:A>G,NM_130837.2:c.1569A>G,NP_570850.2:p.Lys523=,16/31,\N,Unknown significance,\N,synonymous_variant,5.885,0.0000149925,EXAC_NFE_AF,OPA1
609585,3:193361860:A>G,NM_130837.2:c.1574A>G,NP_570850.2:p.Asp525Gly,16/31,\N,Pathogenic,Optic atrophy 1,missense_variant,29.5,\N,\N,OPA1
609586,3:193361867:A>G,NM_130837.2:c.1581A>G,NP_570850.2:p.Ala527=,16/31,\N,Unknown significance,\N,synonymous_variant,11.33,0.0000149912,EXAC_NFE_AF,OPA1
609587,3:193361876:T>A,NM_130837.2:c.1590T>A,NP_570850.2:p.Asn530Lys,16/31,\N,Unknown significance,\N,missense_variant,28.8,\N,\N,OPA1
609588,3:193361877:G>A,NM_130837.2:c.1591G>A,NP_570850.2:p.Val531Ile,16/31,\N,Unknown significance,\N,missense_variant,22.8,\N,\N,OPA1
609589,3:193361877:G>T,NM_130837.2:c.1591G>T,NP_570850.2:p.Val531Leu,16/31,\N,Unknown significance,\N,missense_variant,16.01,\N,\N,OPA1
609590,3:193361883:A>G,NM_130837.2:c.1597A>G,NP_570850.2:p.Ser533Gly,16/31,\N,Unknown significance,\N,missense_variant,23,0.0000149925,EXAC_NFE_AF,OPA1
609591,3:193361893:G>A,NM_130834.2:c.1496G>A,NP_570847.2:p.Arg499Lys,15/30,\N,Unknown significance,\N,missense_variant&splice_region_variant,25.6,0.0000149943,EXAC_NFE_AF,OPA1
609592,3:193361894:G>A,NM_130837.2:c.1608G>A,NP_570850.2:p.Arg536=,16/31,\N,Unknown significance,\N,splice_region_variant&synonymous_variant,14.85,0.0000299913,EXAC_NFE_AF,OPA1
609593,3:193361899:G>C,NM_130837.2:c.1608+5G>C,\N,\N,16/30,Unknown significance,\N,splice_region_variant&intron_variant,12.54,0.000116279,EVS_EA_AF,OPA1
609594,3:193361913:T>C,NM_130837.2:c.1608+19T>C,\N,\N,16/30,Unknown significance,\N,intron_variant,6.618,0.0000605987,EXAC_SAS_AF,OPA1
609595,3:193361914:T>A,NM_130837.2:c.1608+20T>A,\N,\N,16/30,Unknown significance,\N,intron_variant,8.913,0.0000605987,EXAC_SAS_AF,OPA1
609596,3:193361916:C>G,NM_130837.2:c.1608+22C>G,\N,\N,16/30,Unknown significance,\N,intron_variant,3.364,0.0000150074,EXAC_NFE_AF,OPA1
609597,3:193361916:C>T,NM_130837.2:c.1608+22C>T,\N,\N,16/30,Unknown significance,\N,intron_variant,4.838,0.0038,1KG_AFR_AF,OPA1
609598,3:193361917:G>A,NM_130837.2:c.1608+23G>A,\N,\N,16/30,Benign,\N,intron_variant,0.711,0.116293,EXAC_FIN_AF,OPA1
609599,3:193361930:T>A,NM_130837.2:c.1608+36T>A,\N,\N,16/30,Unknown significance,\N,intron_variant,8.111,0.0000150245,EXAC_NFE_AF,OPA1
609600,3:193361932:G>A,NM_130837.2:c.1608+38G>A,\N,\N,16/30,Unknown significance,\N,intron_variant,5.999,0.000116279,EVS_EA_AF,OPA1
609601,3:193361939:C>T,NM_130837.2:c.1608+45C>T,\N,\N,16/30,Unknown significance,\N,intron_variant,6.671,0.0008,1KG_AFR_AF,OPA1
609602,3:193361952:A>G,NM_130837.2:c.1608+58A>G,\N,\N,16/30,Unknown significance,\N,intron_variant,4.48,0.001,1KG_SAS_AF,OPA1
609603,3:193361971:A>C,NM_130837.2:c.1608+77A>C,\N,\N,16/30,Unknown significance,\N,intron_variant,0.391,0.001,1KG_SAS_AF,OPA1
609604,3:193361986:C>A,NM_130837.2:c.1608+92C>A,\N,\N,16/30,Unknown significance,\N,intron_variant,0.822,0.0038,1KG_AFR_AF,OPA1
609605,3:193361993:A>C,NM_130837.2:c.1608+99A>C,\N,\N,16/30,Unknown significance,\N,intron_variant,0.117,0.0008,1KG_AFR_AF,OPA1
609606,3:193362032:G>A,NM_130837.2:c.1608+138G>A,\N,\N,16/30,Benign,\N,intron_variant,1.926,0.0204,1KG_AFR_AF,OPA1
609607,3:193362046:G>A,NM_130837.2:c.1608+152G>A,\N,\N,16/30,Unknown significance,\N,intron_variant,4.975,0.002,1KG_EAS_AF,OPA1
609608,3:193362071:G>A,NM_130837.2:c.1608+177G>A,\N,\N,16/30,Unknown significance,\N,intron_variant,5.871,\N,\N,OPA1
609609,3:193362086:C>T,NM_130837.2:c.1608+192C>T,\N,\N,16/30,Unknown significance,\N,intron_variant,4.412,0.0029,1KG_AMR_AF,OPA1
609610,3:193362112:G>A,NM_130837.2:c.1608+218G>A,\N,\N,16/30,Unknown significance,\N,intron_variant,2.081,\N,\N,OPA1
609611,3:193362114:A>G,NM_130837.2:c.1608+220A>G,\N,\N,16/30,Unknown significance,\N,intron_variant,6.657,\N,\N,OPA1
609612,3:193362137:T>G,NM_130837.2:c.1608+243T>G,\N,\N,16/30,Unknown significance,\N,intron_variant,6.83,\N,\N,OPA1
609613,3:193362143:A>G,NM_130837.2:c.1608+249A>G,\N,\N,16/30,Unknown significance,\N,intron_variant,5.42,0.0015,1KG_AFR_AF,OPA1
609614,3:193362184:C>G,NM_130837.2:c.1608+290C>G,\N,\N,16/30,Benign,\N,intron_variant,2.009,0.0265,1KG_AFR_AF,OPA1
609615,3:193362189:G>A,NM_130837.2:c.1608+295G>A,\N,\N,16/30,Benign,\N,intron_variant,4.024,0.4265,1KG_AMR_AF,OPA1
609616,3:193362204:G>C,NM_130837.2:c.1608+310G>C,\N,\N,16/30,Unknown significance,\N,intron_variant,0.334,0.0014,1KG_AMR_AF,OPA1
609617,3:193362212:C>T,NM_130837.2:c.1608+318C>T,\N,\N,16/30,Unknown significance,\N,intron_variant,3.194,0.001,1KG_EAS_AF,OPA1
609618,3:193362265:AC>A,NM_130837.2:c.1608+373del,\N,\N,16/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
609619,3:193362297:A>G,NM_130837.2:c.1608+403A>G,\N,\N,16/30,Unknown significance,\N,intron_variant,1.229,\N,\N,OPA1
609620,3:193362301:G>A,NM_130837.2:c.1608+407G>A,\N,\N,16/30,Benign,\N,intron_variant,4.42,0.0129,1KG_AFR_AF,OPA1
609621,3:193362341:A>G,NM_130837.2:c.1608+447A>G,\N,\N,16/30,Unknown significance,\N,intron_variant,3.555,\N,\N,OPA1
609622,3:193362353:C>A,NM_130837.2:c.1608+459C>A,\N,\N,16/30,Unknown significance,\N,intron_variant,6.418,0.001,1KG_EUR_AF,OPA1
609623,3:193362356:G>T,NM_130837.2:c.1608+462G>T,\N,\N,16/30,Unknown significance,\N,intron_variant,1.885,\N,\N,OPA1
609624,3:193362365:A>C,NM_130837.2:c.1608+471A>C,\N,\N,16/30,Unknown significance,\N,intron_variant,5.374,\N,\N,OPA1
609625,3:193362374:T>G,NM_130837.2:c.1608+480T>G,\N,\N,16/30,Unknown significance,\N,intron_variant,9.177,\N,\N,OPA1
609626,3:193362377:T>C,NM_130837.2:c.1608+483T>C,\N,\N,16/30,Unknown significance,\N,intron_variant,7.801,0.001,1KG_EUR_AF,OPA1
609627,3:193362384:C>A,NM_130837.2:c.1608+490C>A,\N,\N,16/30,Unknown significance,\N,intron_variant,5.75,\N,\N,OPA1
609628,3:193362387:T>C,NM_130837.2:c.1608+493T>C,\N,\N,16/30,Unknown significance,\N,intron_variant,6.347,\N,\N,OPA1
609629,3:193362426:C>T,NM_130837.2:c.1608+532C>T,\N,\N,16/30,Unknown significance,\N,intron_variant,4.699,0.0014,1KG_AMR_AF,OPA1
609630,3:193362440:T>C,NM_130837.2:c.1608+546T>C,\N,\N,16/30,Benign,\N,intron_variant,1.914,1,1KG_EAS_AF,OPA1
609631,3:193362463:G>A,NM_130837.2:c.1608+569G>A,\N,\N,16/30,Unknown significance,\N,intron_variant,3.597,\N,\N,OPA1
609632,3:193362470:C>T,NM_130837.2:c.1608+576C>T,\N,\N,16/30,Unknown significance,\N,intron_variant,2.885,0.001,1KG_EAS_AF,OPA1
609633,3:193362471:G>A,NM_130837.2:c.1608+577G>A,\N,\N,16/30,Unknown significance,\N,intron_variant,0.822,\N,\N,OPA1
609634,3:193362482:G>A,NM_130837.2:c.1608+588G>A,\N,\N,16/30,Unknown significance,\N,intron_variant,5.576,0.001,1KG_EAS_AF,OPA1
609635,3:193362503:A>T,NM_130837.2:c.1608+609A>T,\N,\N,16/30,Unknown significance,\N,intron_variant,13.29,0.001,1KG_EAS_AF|1KG_EUR_AF,OPA1
609636,3:193362537:T>G,NM_130837.2:c.1608+643T>G,\N,\N,16/30,Unknown significance,\N,intron_variant,5.223,\N,\N,OPA1
609637,3:193362576:A>G,NM_130837.2:c.1608+682A>G,\N,\N,16/30,Unknown significance,\N,intron_variant,3.26,\N,\N,OPA1
609638,3:193362636:A>G,NM_130837.2:c.1609-706A>G,\N,\N,16/30,Unknown significance,\N,intron_variant,12.25,0.001,1KG_EUR_AF,OPA1
609639,3:193362637:TA>T,NM_130837.2:c.1609-701del,\N,\N,16/30,Unknown significance,\N,intron_variant,14.06,0.0023,1KG_AFR_AF,OPA1
609640,3:193362666:C>T,NM_130837.2:c.1609-676C>T,\N,\N,16/30,Benign,\N,intron_variant,5.662,0.3933,1KG_AFR_AF,OPA1
609641,3:193362726:A>C,NM_130837.2:c.1609-616A>C,\N,\N,16/30,Benign,\N,intron_variant,1.567,0.0091,1KG_AFR_AF,OPA1
609642,3:193362739:G>T,NM_130837.2:c.1609-603G>T,\N,\N,16/30,Unknown significance,\N,intron_variant,1.358,\N,\N,OPA1
609643,3:193362769:T>G,NM_130837.2:c.1609-573T>G,\N,\N,16/30,Unknown significance,\N,intron_variant,2.989,0.0015,1KG_AFR_AF,OPA1
609644,3:193362778:A>G,NM_130837.2:c.1609-564A>G,\N,\N,16/30,Unknown significance,\N,intron_variant,3.071,\N,\N,OPA1
609645,3:193362782:TC>T,NM_130837.2:c.1609-559del,\N,\N,16/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
609646,3:193362783:CTT>C,NM_130837.2:c.1609-547_1609-546del,\N,\N,16/30,Unknown significance,\N,intron_variant,5.397,\N,\N,OPA1
609647,3:193362798:G>A,NM_130837.2:c.1609-544G>A,\N,\N,16/30,Benign,\N,intron_variant,0.46,0.5938,1KG_AFR_AF,OPA1
609648,3:193362824:C>T,NM_130837.2:c.1609-518C>T,\N,\N,16/30,Unknown significance,\N,intron_variant,12.69,0.0015,1KG_AFR_AF,OPA1
609649,3:193362846:G>T,NM_130837.2:c.1609-496G>T,\N,\N,16/30,Unknown significance,\N,intron_variant,8.563,\N,\N,OPA1
609650,3:193362898:C>T,NM_130837.2:c.1609-444C>T,\N,\N,16/30,Unknown significance,\N,intron_variant,2.582,0.001,1KG_EAS_AF,OPA1
609651,3:193362906:CT>C,NM_130837.2:c.1609-434del,\N,\N,16/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
609652,3:193362931:G>T,NM_130837.2:c.1609-411G>T,\N,\N,16/30,Unknown significance,\N,intron_variant,3.011,\N,\N,OPA1
609653,3:193362935:G>C,NM_130837.2:c.1609-407G>C,\N,\N,16/30,Unknown significance,\N,intron_variant,1.608,\N,\N,OPA1
609654,3:193362948:A>G,NM_130837.2:c.1609-394A>G,\N,\N,16/30,Benign,\N,intron_variant,12.51,0.0083,1KG_AFR_AF,OPA1
609655,3:193362976:A>G,NM_130837.2:c.1609-366A>G,\N,\N,16/30,Unknown significance,\N,intron_variant,0.683,\N,\N,OPA1
609656,3:193362983:GCACTGTATCAT>G,NM_130837.2:c.1609-358_1609-348del,\N,\N,16/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
609657,3:193363017:CT>C,NM_130837.2:c.1609-320del,\N,\N,16/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
609658,3:193363043:T>C,NM_130837.2:c.1609-299T>C,\N,\N,16/30,Unknown significance,\N,intron_variant,2.731,\N,\N,OPA1
609659,3:193363044:T>G,NM_130837.2:c.1609-298T>G,\N,\N,16/30,Unknown significance,\N,intron_variant,5.598,\N,\N,OPA1
609660,3:193363048:G>A,NM_130837.2:c.1609-294G>A,\N,\N,16/30,Benign,\N,intron_variant,1.824,0.007,1KG_EUR_AF,OPA1
609661,3:193363051:G>A,NM_130837.2:c.1609-291G>A,\N,\N,16/30,Unknown significance,\N,intron_variant,1.291,0.004,1KG_EAS_AF,OPA1
609662,3:193363053:A>T,NM_130837.2:c.1609-289A>T,\N,\N,16/30,Unknown significance,\N,intron_variant,2.135,0.002,1KG_SAS_AF,OPA1
609663,3:193363078:A>G,NM_130837.2:c.1609-264A>G,\N,\N,16/30,Unknown significance,\N,intron_variant,5.023,\N,\N,OPA1
609664,3:193363111:T>C,NM_130837.2:c.1609-231T>C,\N,\N,16/30,Unknown significance,\N,intron_variant,3.372,0.0008,1KG_AFR_AF,OPA1
609665,3:193363120:T>C,NM_130837.2:c.1609-222T>C,\N,\N,16/30,Unknown significance,\N,intron_variant,4.11,\N,\N,OPA1
609666,3:193363123:C>T,NM_130837.2:c.1609-219C>T,\N,\N,16/30,Unknown significance,\N,intron_variant,3.758,\N,\N,OPA1
609667,3:193363131:C>A,NM_130837.2:c.1609-211C>A,\N,\N,16/30,Unknown significance,\N,intron_variant,0.167,\N,\N,OPA1
609668,3:193363131:C>T,NM_130837.2:c.1609-211C>T,\N,\N,16/30,Unknown significance,\N,intron_variant,0.176,\N,\N,OPA1
609669,3:193363132:G>A,NM_130837.2:c.1609-210G>A,\N,\N,16/30,Benign,\N,intron_variant,0.633,0.0069,1KG_EAS_AF,OPA1
609670,3:193363136:C>T,NM_130837.2:c.1609-206C>T,\N,\N,16/30,Unknown significance,\N,intron_variant,0.458,0.001,1KG_EAS_AF,OPA1
609671,3:193363146:A>C,NM_130837.2:c.1609-196A>C,\N,\N,16/30,Unknown significance,\N,intron_variant,2.486,\N,\N,OPA1
609672,3:193363161:A>G,NM_130837.2:c.1609-181A>G,\N,\N,16/30,Unknown significance,\N,intron_variant,2.741,0.0029,1KG_AMR_AF,OPA1
609673,3:193363163:G>A,NM_130837.2:c.1609-179G>A,\N,\N,16/30,Benign,\N,intron_variant,5.341,0.4682,1KG_AFR_AF,OPA1
609674,3:193363222:G>C,NM_130837.2:c.1609-120G>C,\N,\N,16/30,Unknown significance,\N,intron_variant,2.96,\N,\N,OPA1
609675,3:193363225:C>G,NM_130837.2:c.1609-117C>G,\N,\N,16/30,Unknown significance,\N,intron_variant,3.976,\N,\N,OPA1
609676,3:193363230:T>G,NM_130837.2:c.1609-112T>G,\N,\N,16/30,Unknown significance,\N,intron_variant,7.614,\N,\N,OPA1
609677,3:193363267:T>C,NM_130837.2:c.1609-75T>C,\N,\N,16/30,Benign,\N,intron_variant,16.44,0.0875,1KG_EUR_AF,OPA1
609678,3:193363298:T>A,NM_130837.2:c.1609-44T>A,\N,\N,16/30,Unknown significance,\N,intron_variant,7.219,0.0000207125,EXAC_NFE_AF,OPA1
609679,3:193363298:T>C,NM_130837.2:c.1609-44T>C,\N,\N,16/30,Unknown significance,\N,intron_variant,4.516,0.0029,1KG_AMR_AF,OPA1
609680,3:193363301:A>G,NM_130837.2:c.1609-41A>G,\N,\N,16/30,Unknown significance,\N,intron_variant,4.856,0.000111832,EXAC_AMR_AF,OPA1
609681,3:193363303:A>T,NM_130837.2:c.1609-39A>T,\N,\N,16/30,Unknown significance,\N,intron_variant,0.812,0.000159236,EXAC_EAS_AF,OPA1
609682,3:193363304:C>G,NM_130837.2:c.1609-38C>G,\N,\N,16/30,Unknown significance,\N,intron_variant,1.564,0.001,1KG_EAS_AF,OPA1
609683,3:193363306:A>C,NM_130837.2:c.1609-36A>C,\N,\N,16/30,Unknown significance,\N,intron_variant,3.469,0.000117261,EVS_EA_AF,OPA1
609684,3:193363312:C>A,NM_130837.2:c.1609-30C>A,\N,\N,16/30,Unknown significance,\N,intron_variant,11.12,0.000229253,EVS_AA_AF,OPA1
609685,3:193363315:A>G,NM_130837.2:c.1609-27A>G,\N,\N,16/30,Unknown significance,\N,intron_variant,9.339,0.000117151,EVS_EA_AF,OPA1
609686,3:193363319:A>AT,NM_130837.2:c.1609-18dup,\N,\N,16/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
609687,3:193363335:A>T,NM_130837.2:c.1609-7A>T,\N,\N,16/30,Unknown significance,\N,splice_region_variant&intron_variant,10.44,0.0000350865,EXAC_NFE_AF,OPA1
609688,3:193363338:A>G,NM_130837.2:c.1609-4A>G,\N,\N,16/30,Unknown significance,\N,splice_region_variant&intron_variant,13.19,0.000116713,EVS_EA_AF,OPA1
609689,3:193363341:G>C,NM_130837.2:c.1609-1G>C,\N,\N,16/30,Pathogenic,Optic atrophy 1,splice_acceptor_variant,26.1,\N,\N,OPA1
609690,3:193363341:G>T,NM_130837.2:c.1609-1G>T,\N,\N,16/30,Pathogenic,Optic atrophy 1,splice_acceptor_variant,26.3,\N,\N,OPA1
609691,3:193363345:C>T,NM_130837.2:c.1612C>T,NP_570850.2:p.Gln538Ter,17/31,\N,Pathogenic,Optic atrophy 1,stop_gained,41,\N,\N,OPA1
609692,3:193363346:A>G,NM_130837.2:c.1613A>G,NP_570850.2:p.Gln538Arg,17/31,\N,Unknown significance,\N,missense_variant,12.11,0.000108319,EXAC_AFR_AF,OPA1
609693,3:193363347:G>A,NM_130837.2:c.1614G>A,NP_570850.2:p.Gln538=,17/31,\N,Unknown significance,\N,synonymous_variant,9.515,0.0000643252,EXAC_SAS_AF,OPA1
609694,3:193363354:A>C,NM_130837.2:c.1621A>C,NP_570850.2:p.Ile541Leu,17/31,\N,Unknown significance,\N,missense_variant,13.22,0.00011655,EVS_EA_AF,OPA1
609695,3:193363354:A>T,NM_130837.2:c.1621A>T,NP_570850.2:p.Ile541Phe,17/31,\N,Unknown significance,\N,missense_variant,23.9,0.0000160431,EXAC_NFE_AF,OPA1
609696,3:193363357:G>A,NM_015560.2:c.1459G>A,NP_056375.2:p.Glu487Lys,15/29,\N,Pathogenic,Optic atrophy 1,missense_variant,26.7,\N,\N,OPA1
609697,3:193363360:G>A,NM_130837.2:c.1627G>A,NP_570850.2:p.Gly543Arg,17/31,\N,Pathogenic,Progressive external ophthalmoplegia & ataxia,missense_variant,32,\N,\N,OPA1
609698,3:193363363:A>G,NM_015560.2:c.1465A>G,NP_056375.2:p.Lys489Glu,15/29,\N,Unknown significance,\N,missense_variant,24.8,0.001,1KG_EAS_AF,OPA1
609699,3:193363365:G>A,NM_130837.2:c.1632G>A,NP_570850.2:p.Lys544=,17/31,\N,Unknown significance,\N,synonymous_variant,12.49,0.0000621427,EXAC_SAS_AF,OPA1
609700,3:193363372:CC>TA,NM_130837.2:c.1639_1640delinsTA,NP_570850.2:p.Pro547Ter,17/31,\N,Pathogenic,Optic atrophy 1,stop_gained,39,\N,\N,OPA1
609701,3:193363378:AAAGCTTTAGGTTAT>A,NM_130837.2:c.1646_1659del,NP_570850.2:p.Lys549IlefsTer12,17/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,35,\N,\N,OPA1
609702,3:193363382:C>T,NM_130837.2:c.1649C>T,NP_570850.2:p.Ala550Val,17/31,\N,Pathogenic,Progressive external ophthalmoplegia & deafness,missense_variant,34,\N,\N,OPA1
609703,3:193363391:AT>A,NM_130837.2:c.1662del,NP_570850.2:p.Phe554LeufsTer4,17/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,34,\N,\N,OPA1
609704,3:193363398:T>C,NM_130837.2:c.1665T>C,NP_570850.2:p.Ala555=,17/31,\N,Unknown significance,\N,synonymous_variant,8.687,0.0000152915,EXAC_NFE_AF,OPA1
609705,3:193363406:C>A,NM_130837.2:c.1673C>A,NP_570850.2:p.Thr558Lys,17/31,\N,Pathogenic,Optic atrophy 1,missense_variant,34,\N,\N,OPA1
609706,3:193363413:A>C,NM_015560.2:c.1515A>C,NP_056375.2:p.Lys505Asn,15/29,\N,Pathogenic,Optic atrophy 1,missense_variant&splice_region_variant,27.2,\N,\N,OPA1
609707,3:193363413:A>G,NM_130837.2:c.1680A>G,NP_570850.2:p.Lys560=,17/31,\N,Pathogenic,Optic atrophy 1,splice_region_variant&synonymous_variant,15.36,\N,\N,OPA1
609708,3:193363415:G>A,NM_130837.2:c.1681+1G>A,\N,\N,17/30,Pathogenic,Optic atrophy & auditory neuropathy,splice_donor_variant,27.6,\N,\N,OPA1
609709,3:193363415:G>C,NM_130837.2:c.1681+1G>C,\N,\N,17/30,Pathogenic,Optic atrophy 1,splice_donor_variant,26,\N,\N,OPA1
609710,3:193363415:G>T,NM_130837.2:c.1681+1G>T,\N,\N,17/30,Pathogenic,Optic atrophy 1,splice_donor_variant,26.1,\N,\N,OPA1
609711,3:193363429:A>C,NM_130837.2:c.1681+15A>C,\N,\N,17/30,Unknown significance,\N,intron_variant,0.065,0.0000152022,EXAC_NFE_AF,OPA1
609712,3:193363437:A>G,NM_130837.2:c.1681+23A>G,\N,\N,17/30,Unknown significance,\N,intron_variant,1.481,0.00279851,EVS_EA_AF,OPA1
609713,3:193363440:T>G,NM_130837.2:c.1681+26T>G,\N,\N,17/30,Unknown significance,\N,intron_variant,3.473,0.000087108,EXAC_AMR_AF,OPA1
609714,3:193363442:A>C,NM_130837.2:c.1681+28A>C,\N,\N,17/30,Unknown significance,\N,intron_variant,0.794,0.000121462,EXAC_SAS_AF,OPA1
609715,3:193363448:A>G,NM_130837.2:c.1681+34A>G,\N,\N,17/30,Unknown significance,\N,intron_variant,7.835,0.000121433,EXAC_SAS_AF,OPA1
609716,3:193363458:G>A,NM_130837.2:c.1681+44G>A,\N,\N,17/30,Unknown significance,\N,intron_variant,0.409,0.000060687,EXAC_SAS_AF,OPA1
609717,3:193363470:TAA>T,NM_130837.2:c.1682-45_1682-44del,\N,\N,17/30,Unknown significance,\N,intron_variant,6.13,0.0000604357,EXAC_NFE_AF,OPA1
609718,3:193363471:A>C,NM_130837.2:c.1682-46A>C,\N,\N,17/30,Unknown significance,\N,intron_variant,0.067,\N,\N,OPA1
609719,3:193363479:A>C,NM_130837.2:c.1682-38A>C,\N,\N,17/30,Unknown significance,\N,intron_variant,0.208,0.000181995,EXAC_SAS_AF,OPA1
609720,3:193363485:T>G,NM_130837.2:c.1682-32T>G,\N,\N,17/30,Unknown significance,\N,intron_variant,10.26,0.000151286,EXAC_FIN_AF,OPA1
609721,3:193363487:G>A,NM_130837.2:c.1682-30G>A,\N,\N,17/30,Unknown significance,\N,intron_variant,6.651,0.000116036,EXAC_EAS_AF,OPA1
609722,3:193363492:A>G,NM_130837.2:c.1682-25A>G,\N,\N,17/30,Unknown significance,\N,intron_variant,9.507,0.0000301969,EXAC_NFE_AF,OPA1
609723,3:193363493:A>G,NM_130837.2:c.1682-24A>G,\N,\N,17/30,Unknown significance,\N,intron_variant,8.842,\N,\N,OPA1
609724,3:193363494:A>T,NM_130837.2:c.1682-23A>T,\N,\N,17/30,Unknown significance,\N,intron_variant,3.233,0.0000606649,EXAC_SAS_AF,OPA1
609725,3:193363496:T>G,NM_130837.2:c.1682-21T>G,\N,\N,17/30,Unknown significance,\N,intron_variant,4.744,0.001,1KG_EUR_AF,OPA1
609726,3:193363499:AC>A,NM_130837.2:c.1682-16del,\N,\N,17/30,Unknown significance,\N,intron_variant,0.331,0.00184011,EXAC_AFR_AF,OPA1
609727,3:193363502:A>G,NM_130837.2:c.1682-15A>G,\N,\N,17/30,Unknown significance,\N,intron_variant,0.08,0.0000150953,EXAC_NFE_AF,OPA1
609728,3:193363506:T>A,NM_130837.2:c.1682-11T>A,\N,\N,17/30,Unknown significance,\N,intron_variant,2.472,0.0000150966,EXAC_NFE_AF,OPA1
609729,3:193363514:C>T,NM_130837.2:c.1682-3C>T,\N,\N,17/30,Unknown significance,\N,splice_region_variant&intron_variant,13.3,0.0000151035,EXAC_NFE_AF,OPA1
609730,3:193363519:A>T,NM_130837.2:c.1684A>T,NP_570850.2:p.Asn562Tyr,18/31,\N,Unknown significance,\N,missense_variant&splice_region_variant,27.1,0.000060687,EXAC_SAS_AF,OPA1
609731,3:193363532:G>A,NM_015560.2:c.1532G>A,NP_056375.2:p.Ser511Asn,16/29,\N,Unknown significance,\N,missense_variant,28.8,0.000116117,EXAC_EAS_AF,OPA1
609732,3:193363535:T>C,NM_130837.2:c.1700T>C,NP_570850.2:p.Ile567Thr,18/31,\N,Unknown significance,\N,missense_variant,28.7,0.0015,1KG_AFR_AF,OPA1
609733,3:193363541:CTA>C,NM_130837.2:c.1709_1710del,NP_570850.2:p.Ile570LysfsTer4,18/31,\N,Pathogenic,Optic atrophy,frameshift_variant,35,\N,\N,OPA1
609734,3:193363543:A>C,NM_130837.2:c.1708A>C,NP_570850.2:p.Ile570Leu,18/31,\N,Unknown significance,\N,missense_variant,29.4,0.000182482,EXAC_SAS_AF,OPA1
609735,3:193363549:G>C,NM_130837.2:c.1714G>C,NP_570850.2:p.Glu572Gln,18/31,\N,Unknown significance,\N,missense_variant,18.1,0.0000151543,EXAC_NFE_AF,OPA1
609736,3:193363554:TGAA>T,NM_130837.2:c.1725_1727del,NP_570850.2:p.Glu576del,18/31,\N,Pathogenic,Optic atrophy 1,inframe_deletion,22.5,\N,\N,OPA1
609737,3:193363554:T>C,NM_130837.2:c.1719T>C,NP_570850.2:p.Tyr573=,18/31,\N,Unknown significance,\N,synonymous_variant,2.087,0.0000151635,EXAC_NFE_AF,OPA1
609738,3:193363563:G>T,NM_130837.2:c.1728G>T,NP_570850.2:p.Glu576Asp,18/31,\N,Unknown significance,\N,missense_variant,10.01,0.0000151819,EXAC_NFE_AF,OPA1
609739,3:193363563:G>GT,NM_130837.2:c.1734dup,NP_570850.2:p.Gln579SerfsTer38,18/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,35,\N,\N,OPA1
609740,3:193363570:CA>C,NM_130837.2:c.1736del,NP_570850.2:p.Gln579ArgfsTer6,18/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,35,\N,\N,OPA1
609741,3:193363572:G>C,NM_130837.2:c.1737G>C,NP_570850.2:p.Gln579His,18/31,\N,Unknown significance,\N,missense_variant,21,0.001,1KG_SAS_AF,OPA1
609742,3:193363579:A>G,NM_130837.2:c.1744A>G,NP_570850.2:p.Lys582Glu,18/31,\N,Unknown significance,\N,missense_variant,23.1,0.00008726,EXAC_AMR_AF,OPA1
609743,3:193363580:A>G,NM_130837.2:c.1745A>G,NP_570850.2:p.Lys582Arg,18/31,\N,Unknown significance,\N,missense_variant,14.29,0.000121996,EXAC_SAS_AF,OPA1
609744,3:193363581:G>A,NM_130837.2:c.1746G>A,NP_570850.2:p.Lys582=,18/31,\N,Unknown significance,\N,synonymous_variant,8.762,0.00008726,EXAC_AMR_AF,OPA1
609745,3:193363587:A>G,NM_130837.2:c.1752A>G,NP_570850.2:p.Leu584=,18/31,\N,Unknown significance,\N,splice_region_variant&synonymous_variant,7.607,0.0008,1KG_AFR_AF,OPA1
609746,3:193363592:A>T,NM_130837.2:c.1754+3A>T,\N,\N,18/30,Unknown significance,\N,splice_region_variant&intron_variant,8.838,0.0000153487,EXAC_NFE_AF,OPA1
609747,3:193363600:TG>T,NM_130837.2:c.1754+12del,\N,\N,18/30,Unknown significance,\N,intron_variant,4.345,0.0000154823,EXAC_NFE_AF,OPA1
609748,3:193363601:G>GT,NM_130837.2:c.1754+14dup,\N,\N,18/30,Unknown significance,\N,intron_variant,3.037,0.0000154866,EXAC_NFE_AF,OPA1
609749,3:193363603:TAAAACATTTA>T,NM_130837.2:c.1754+17_1754+26del,\N,\N,18/30,Unknown significance,\N,intron_variant,8.445,\N,\N,OPA1
609750,3:193363609:A>G,NM_130837.2:c.1754+20A>G,\N,\N,18/30,Unknown significance,\N,intron_variant,1.959,0.001,1KG_SAS_AF,OPA1
609751,3:193363611:T>A,NM_130837.2:c.1754+22T>A,\N,\N,18/30,Unknown significance,\N,intron_variant,7.777,0.0000616295,EXAC_SAS_AF,OPA1
609752,3:193363611:T>G,NM_130837.2:c.1754+22T>G,\N,\N,18/30,Benign,\N,intron_variant,6.388,0.0058,1KG_AMR_AF,OPA1
609753,3:193363622:A>C,NM_130837.2:c.1754+33A>C,\N,\N,18/30,Unknown significance,\N,intron_variant,2.4,0.001,1KG_SAS_AF,OPA1
609754,3:193363624:A>G,NM_130837.2:c.1754+35A>G,\N,\N,18/30,Unknown significance,\N,intron_variant,2.994,0.0000317178,EXAC_NFE_AF,OPA1
609755,3:193363635:A>G,NM_130837.2:c.1754+46A>G,\N,\N,18/30,Unknown significance,\N,intron_variant,8.2,0.0000160472,EXAC_NFE_AF,OPA1
609756,3:193363659:T>A,NM_130837.2:c.1754+70T>A,\N,\N,18/30,Unknown significance,\N,intron_variant,6.615,0.001,1KG_SAS_AF,OPA1
609757,3:193363695:G>A,NM_130837.2:c.1754+106G>A,\N,\N,18/30,Benign,\N,intron_variant,0.974,0.1501,1KG_EUR_AF,OPA1
609758,3:193363742:G>A,NM_130837.2:c.1754+153G>A,\N,\N,18/30,Unknown significance,\N,intron_variant,3.615,\N,\N,OPA1
609759,3:193363794:A>T,NM_130837.2:c.1754+205A>T,\N,\N,18/30,Unknown significance,\N,intron_variant,2.24,0.0008,1KG_AFR_AF,OPA1
609760,3:193363804:A>G,NM_130837.2:c.1754+215A>G,\N,\N,18/30,Benign,\N,intron_variant,3.47,0.005,1KG_EAS_AF,OPA1
609761,3:193363808:T>C,NM_130837.2:c.1754+219T>C,\N,\N,18/30,Unknown significance,\N,intron_variant,1.056,0.001,1KG_EAS_AF,OPA1
609762,3:193363818:G>A,NM_130837.2:c.1754+229G>A,\N,\N,18/30,Unknown significance,\N,intron_variant,2.161,0.001,1KG_EAS_AF,OPA1
609763,3:193363830:A>G,NM_130837.2:c.1754+241A>G,\N,\N,18/30,Benign,\N,intron_variant,2.105,0.005,1KG_EAS_AF,OPA1
609764,3:193363835:A>G,NM_130837.2:c.1754+246A>G,\N,\N,18/30,Unknown significance,\N,intron_variant,3.979,\N,\N,OPA1
609765,3:193363850:TCTTA>T,NM_130837.2:c.1754+265_1754+268del,\N,\N,18/30,Unknown significance,\N,intron_variant,6.822,\N,\N,OPA1
609766,3:193363854:A>G,NM_130837.2:c.1754+265A>G,\N,\N,18/30,Benign,\N,intron_variant,5.029,0.3221,1KG_SAS_AF,OPA1
609767,3:193363854:ACTTTA>GC,NM_130837.2:c.1754+265_1754+270delinsGC,\N,\N,18/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
609768,3:193363855:C>CTTTA,NM_130837.2:c.1754+270_1754+273dup,\N,\N,18/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
609769,3:193363855:CTTTA>C,NM_130837.2:c.1754+270_1754+273del,\N,\N,18/30,Benign,\N,intron_variant,6.922,0.4274,1KG_EUR_AF,OPA1
609770,3:193363865:C>T,NM_130837.2:c.1754+276C>T,\N,\N,18/30,Benign,\N,intron_variant,6.386,0.0367,1KG_EAS_AF,OPA1
609771,3:193363889:G>A,NM_130837.2:c.1754+300G>A,\N,\N,18/30,Unknown significance,\N,intron_variant,2.013,0.0008,1KG_AFR_AF,OPA1
609772,3:193363894:T>A,NM_130837.2:c.1754+305T>A,\N,\N,18/30,Benign,\N,intron_variant,11.67,0.0179,1KG_EAS_AF,OPA1
609773,3:193363927:A>G,NM_130837.2:c.1754+338A>G,\N,\N,18/30,Unknown significance,\N,intron_variant,4.144,0.0008,1KG_AFR_AF,OPA1
609774,3:193363977:A>G,NM_130837.2:c.1754+388A>G,\N,\N,18/30,Unknown significance,\N,intron_variant,3.526,\N,\N,OPA1
609775,3:193363980:T>A,NM_130837.2:c.1754+391T>A,\N,\N,18/30,Unknown significance,\N,intron_variant,2.204,\N,\N,OPA1
609776,3:193363987:GAGATA>G,NM_130837.2:c.1754+406_1754+410del,\N,\N,18/30,Unknown significance,\N,intron_variant,15.7,0.0023,1KG_AFR_AF,OPA1
609777,3:193363994:G>A,NM_130837.2:c.1754+405G>A,\N,\N,18/30,Unknown significance,\N,intron_variant,17.52,\N,\N,OPA1
609778,3:193364035:C>T,NM_130837.2:c.1754+446C>T,\N,\N,18/30,Unknown significance,\N,intron_variant,5.837,0.0008,1KG_AFR_AF,OPA1
609779,3:193364064:A>G,NM_130837.2:c.1754+475A>G,\N,\N,18/30,Benign,\N,intron_variant,3.097,0.005,1KG_EAS_AF,OPA1
609780,3:193364074:A>G,NM_130837.2:c.1754+485A>G,\N,\N,18/30,Unknown significance,\N,intron_variant,6.127,0.002,1KG_EUR_AF,OPA1
609781,3:193364097:G>A,NM_130837.2:c.1754+508G>A,\N,\N,18/30,Unknown significance,\N,intron_variant,5.044,0.002,1KG_SAS_AF,OPA1
609782,3:193364107:ATAGT>A,NM_130837.2:c.1754+520_1754+523del,\N,\N,18/30,Unknown significance,\N,intron_variant,\N,0.001,1KG_EAS_AF|1KG_EUR_AF,OPA1
609783,3:193364149:A>G,NM_130837.2:c.1754+560A>G,\N,\N,18/30,Unknown significance,\N,intron_variant,5.367,\N,\N,OPA1
609784,3:193364163:G>C,NM_130837.2:c.1754+574G>C,\N,\N,18/30,Unknown significance,\N,intron_variant,2.832,\N,\N,OPA1
609785,3:193364181:T>C,NM_130837.2:c.1754+592T>C,\N,\N,18/30,Unknown significance,\N,intron_variant,0.538,\N,\N,OPA1
609786,3:193364197:G>T,NM_130837.2:c.1754+608G>T,\N,\N,18/30,Unknown significance,\N,intron_variant,0.381,0.0008,1KG_AFR_AF,OPA1
609787,3:193364207:T>A,NM_130837.2:c.1754+618T>A,\N,\N,18/30,Unknown significance,\N,intron_variant,7.014,0.002,1KG_EAS_AF,OPA1
609788,3:193364225:G>A,NM_130837.2:c.1755-629G>A,\N,\N,18/30,Unknown significance,\N,intron_variant,1.933,0.0014,1KG_AMR_AF,OPA1
609789,3:193364274:G>A,NM_130837.2:c.1755-580G>A,\N,\N,18/30,Unknown significance,\N,intron_variant,0.931,\N,\N,OPA1
609790,3:193364303:A>T,NM_130837.2:c.1755-551A>T,\N,\N,18/30,Unknown significance,\N,intron_variant,1.277,\N,\N,OPA1
609791,3:193364325:G>A,NM_130837.2:c.1755-529G>A,\N,\N,18/30,Unknown significance,\N,intron_variant,0.757,\N,\N,OPA1
609792,3:193364353:C>T,NM_130837.2:c.1755-501C>T,\N,\N,18/30,Unknown significance,\N,intron_variant,2.338,0.002,1KG_EAS_AF,OPA1
609793,3:193364366:A>G,NM_130837.2:c.1755-488A>G,\N,\N,18/30,Unknown significance,\N,intron_variant,2.892,\N,\N,OPA1
609794,3:193364379:A>T,NM_130837.2:c.1755-475A>T,\N,\N,18/30,Unknown significance,\N,intron_variant,6.64,0.001,1KG_EAS_AF,OPA1
609795,3:193364397:A>C,NM_130837.2:c.1755-457A>C,\N,\N,18/30,Unknown significance,\N,intron_variant,2.561,0.001,1KG_SAS_AF,OPA1
609796,3:193364410:G>A,NM_130837.2:c.1755-444G>A,\N,\N,18/30,Unknown significance,\N,intron_variant,0.102,\N,\N,OPA1
609797,3:193364418:C>T,NM_130837.2:c.1755-436C>T,\N,\N,18/30,Unknown significance,\N,intron_variant,0.693,\N,\N,OPA1
609798,3:193364453:T>C,NM_130837.2:c.1755-401T>C,\N,\N,18/30,Unknown significance,\N,intron_variant,4.536,0.0031,1KG_SAS_AF,OPA1
609799,3:193364461:G>A,NM_130837.2:c.1755-393G>A,\N,\N,18/30,Benign,\N,intron_variant,3.468,0.006,1KG_EUR_AF,OPA1
609800,3:193364464:A>G,NM_130837.2:c.1755-390A>G,\N,\N,18/30,Unknown significance,\N,intron_variant,2.629,\N,\N,OPA1
609801,3:193364467:C>T,NM_130837.2:c.1755-387C>T,\N,\N,18/30,Unknown significance,\N,intron_variant,0.062,\N,\N,OPA1
609802,3:193364468:G>T,NM_130837.2:c.1755-386G>T,\N,\N,18/30,Benign,\N,intron_variant,1.1,0.3254,1KG_EAS_AF,OPA1
609803,3:193364483:G>T,NM_130837.2:c.1755-371G>T,\N,\N,18/30,Benign,\N,intron_variant,2.001,0.4294,1KG_EUR_AF,OPA1
609804,3:193364485:G>T,NM_130837.2:c.1755-369G>T,\N,\N,18/30,Unknown significance,\N,intron_variant,1.264,\N,\N,OPA1
609805,3:193364486:T>G,NM_130837.2:c.1755-368T>G,\N,\N,18/30,Unknown significance,\N,intron_variant,5.763,\N,\N,OPA1
609806,3:193364518:C>T,NM_130837.2:c.1755-336C>T,\N,\N,18/30,Unknown significance,\N,intron_variant,0.522,0.0008,1KG_AFR_AF,OPA1
609807,3:193364519:G>A,NM_130837.2:c.1755-335G>A,\N,\N,18/30,Unknown significance,\N,intron_variant,2.489,\N,\N,OPA1
609808,3:193364537:G>A,NM_130837.2:c.1755-317G>A,\N,\N,18/30,Unknown significance,\N,intron_variant,1.45,\N,\N,OPA1
609809,3:193364540:C>T,NM_130837.2:c.1755-314C>T,\N,\N,18/30,Benign,\N,intron_variant,0.497,0.006,1KG_EAS_AF,OPA1
609810,3:193364549:A>C,NM_130837.2:c.1755-305A>C,\N,\N,18/30,Benign,\N,intron_variant,0.017,0.0051,1KG_SAS_AF,OPA1
609811,3:193364626:A>G,NM_130837.2:c.1755-228A>G,\N,\N,18/30,Benign,\N,intron_variant,1.997,0.013,1KG_AMR_AF,OPA1
609812,3:193364669:A>G,NM_130837.2:c.1755-185A>G,\N,\N,18/30,Unknown significance,\N,intron_variant,1.608,0.0008,1KG_AFR_AF,OPA1
609813,3:193364671:A>T,NM_130837.2:c.1755-183A>T,\N,\N,18/30,Unknown significance,\N,intron_variant,1.455,0.001,1KG_SAS_AF,OPA1
609814,3:193364721:A>C,NM_130837.2:c.1755-133A>C,\N,\N,18/30,Unknown significance,\N,intron_variant,1.642,\N,\N,OPA1
609815,3:193364743:T>C,NM_130837.2:c.1755-111T>C,\N,\N,18/30,Unknown significance,\N,intron_variant,4.562,\N,\N,OPA1
609816,3:193364756:A>G,NM_130837.2:c.1755-98A>G,\N,\N,18/30,Unknown significance,\N,intron_variant,1.92,\N,\N,OPA1
609817,3:193364803:T>A,NM_130837.2:c.1755-51T>A,\N,\N,18/30,Unknown significance,\N,intron_variant,5.62,\N,\N,OPA1
609818,3:193364805:C>T,NM_130837.2:c.1755-49C>T,\N,\N,18/30,Unknown significance,\N,intron_variant,0.457,0.0000292654,EXAC_NFE_AF,OPA1
609819,3:193364819:A>T,NM_130837.2:c.1755-35A>T,\N,\N,18/30,Unknown significance,\N,intron_variant,7.934,0.000466273,EXAC_AMR_AF,OPA1
609820,3:193364828:T>C,NM_130837.2:c.1755-26T>C,\N,\N,18/30,Unknown significance,\N,intron_variant,5.679,0.0000268039,EXAC_NFE_AF,OPA1
609821,3:193364831:C>G,NM_130837.2:c.1755-23C>G,\N,\N,18/30,Unknown significance,\N,intron_variant,6.232,0.0000259323,EXAC_NFE_AF,OPA1
609822,3:193364831:C>T,NM_130837.2:c.1755-23C>T,\N,\N,18/30,Unknown significance,\N,intron_variant,6.975,0.000226963,EVS_AA_AF,OPA1
609823,3:193364834:T>G,NM_130837.2:c.1755-20T>G,\N,\N,18/30,Unknown significance,\N,intron_variant,2.956,0.0000847889,EXAC_SAS_AF,OPA1
609824,3:193364836:G>T,NM_130837.2:c.1755-18G>T,\N,\N,18/30,Unknown significance,\N,intron_variant,0.117,0.0014,1KG_AMR_AF,OPA1
609825,3:193364838:TA>T,NM_130837.2:c.1755-15del,\N,\N,18/30,Unknown significance,\N,intron_variant,0.526,0.0000236619,EXAC_NFE_AF,OPA1
609826,3:193364839:A>AT,NM_130837.2:c.1755-6dup,\N,\N,18/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
609827,3:193364839:AT>A,NM_130837.2:c.1755-6del,\N,\N,18/30,Unknown significance,\N,intron_variant,0.268,\N,\N,OPA1
609828,3:193364839:ATT>A,NM_130837.2:c.1755-7_1755-6del,\N,\N,18/30,Unknown significance,\N,intron_variant,0.591,\N,\N,OPA1
609829,3:193364841:T>C,NM_130837.2:c.1755-13T>C,\N,\N,18/30,Unknown significance,\N,intron_variant,0.395,0.0000230001,EXAC_NFE_AF,OPA1
609830,3:193364841:T>G,NM_130837.2:c.1755-13T>G,\N,\N,18/30,Unknown significance,\N,intron_variant,0.684,0.000410846,EXAC_SAS_AF,OPA1
609831,3:193364848:TA>T,NM_130837.2:c.1755-4del,\N,\N,18/30,Unknown significance,\N,splice_region_variant&intron_variant,12.2,0.000241779,EXAC_AFR_AF,OPA1
609832,3:193364854:G>T,NM_130834.2:c.1644G>T,NP_570847.2:p.Lys548Asn,18/30,\N,Unknown significance,\N,missense_variant&splice_region_variant,22.8,0.0000179295,EXAC_NFE_AF,OPA1
609833,3:193364861:A>G,NM_130837.2:c.1762A>G,NP_570850.2:p.Met588Val,19/31,\N,Unknown significance,\N,missense_variant,10.58,0.000116279,EVS_EA_AF,OPA1
609834,3:193364866:A>G,NM_130837.2:c.1767A>G,NP_570850.2:p.Leu589=,19/31,\N,Unknown significance,\N,synonymous_variant,9.598,0.0000163924,EXAC_NFE_AF,OPA1
609835,3:193364870:G>A,NM_130837.2:c.1771G>A,NP_570850.2:p.Ala591Thr,19/31,\N,Unknown significance,\N,missense_variant,23,\N,\N,OPA1
609836,3:193364870:G>C,NM_130837.2:c.1771G>C,NP_570850.2:p.Ala591Pro,19/31,\N,Unknown significance,\N,missense_variant,21.6,0.000116279,EVS_EA_AF,OPA1
609837,3:193364872:A>C,NM_130837.2:c.1773A>C,NP_570850.2:p.Ala591=,19/31,\N,Benign,\N,synonymous_variant,2.082,0.0395087,EXAC_AFR_AF,OPA1
609838,3:193364875:C>G,NM_130837.2:c.1776C>G,NP_570850.2:p.His592Gln,19/31,\N,Unknown significance,\N,missense_variant,24.1,0.0000159826,EXAC_NFE_AF,OPA1
609839,3:193364881:GACT>G,NM_130837.2:c.1785_1787del,NP_570850.2:p.Thr596del,19/31,\N,Pathogenic,Optic atrophy 1,inframe_deletion,22.4,\N,\N,OPA1
609840,3:193364882:A>G,NM_130837.2:c.1783A>G,NP_570850.2:p.Thr595Ala,19/31,\N,Unknown significance,\N,missense_variant,28.3,0.0000157973,EXAC_NFE_AF,OPA1
609841,3:193364886:C>T,NM_130837.2:c.1787C>T,NP_570850.2:p.Thr596Ile,19/31,\N,Unknown significance,\N,missense_variant,33,0.0000157124,EXAC_NFE_AF,OPA1
609842,3:193364899:C>A,NM_130837.2:c.1800C>A,NP_570850.2:p.Ser600Arg,19/31,\N,Pathogenic,Optic atrophy 1,missense_variant,32,\N,\N,OPA1
609843,3:193364899:C>G,NM_130837.2:c.1800C>G,NP_570850.2:p.Ser600Arg,19/31,\N,Pathogenic,Optic atrophy 1,missense_variant,29.1,\N,\N,OPA1
609844,3:193364905:A>G,NM_130837.2:c.1806A>G,NP_570850.2:p.Ala602=,19/31,\N,Unknown significance,\N,synonymous_variant,9.825,0.0014,1KG_AMR_AF,OPA1
609845,3:193364906:G>A,NM_130837.2:c.1807G>A,NP_570850.2:p.Val603Ile,19/31,\N,Pathogenic,Optic atrophy & deafness,missense_variant,31,\N,\N,OPA1
609846,3:193364908:A>AT,NM_130837.2:c.1810dup,NP_570850.2:p.Ser604PhefsTer13,19/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,35,\N,\N,OPA1
609847,3:193364913:ACTG>A,NM_130837.2:c.1817_1819del,NP_570850.2:p.Cys606del,19/31,\N,Pathogenic,Optic atrophy 1,inframe_deletion,22.5,\N,\N,OPA1
609848,3:193364916:G>A,NM_130837.2:c.1817G>A,NP_570850.2:p.Cys606Tyr,19/31,\N,Pathogenic,Optic atrophy 1,missense_variant,29.5,\N,\N,OPA1
609849,3:193364917:CT>C,NM_130837.2:c.1822del,NP_570850.2:p.Trp608GlyfsTer56,19/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,35,\N,\N,OPA1
609850,3:193364923:G>GA,NM_130837.2:c.1828dup,NP_570850.2:p.Met610AsnfsTer7,19/31,\N,Pathogenic,Optic atrophy,frameshift_variant,35,\N,\N,OPA1
609851,3:193364930:G>GTA,NM_130837.2:c.1832_1833dup,NP_570850.2:p.Arg612TyrfsTer53,19/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,35,\N,\N,OPA1
609852,3:193364933:C>T,NM_130837.2:c.1834C>T,NP_570850.2:p.Arg612Ter,19/31,\N,Pathogenic,Optic atrophy 1,stop_gained,42,0.000016019,EXAC_NFE_AF,OPA1
609853,3:193364934:G>A,NM_130837.2:c.1835G>A,NP_570850.2:p.Arg612Gln,19/31,\N,Likely pathogenic,Glaucoma,missense_variant,28.1,\N,\N,OPA1
609854,3:193364934:G>C,NM_130837.2:c.1835G>C,NP_570850.2:p.Arg612Pro,19/31,\N,Pathogenic,Optic atrophy,missense_variant,33,\N,\N,OPA1
609855,3:193364951:C>T,NM_130837.2:c.1852C>T,NP_570850.2:p.Gln618Ter,19/31,\N,Pathogenic,Optic atrophy,stop_gained,46,\N,\N,OPA1
609856,3:193364960:A>G,NM_130837.2:c.1861A>G,NP_570850.2:p.Ser621Gly,19/31,\N,Unknown significance,\N,missense_variant,23.1,0.0000701754,EXAC_SAS_AF,OPA1
609857,3:193364970:G>T,NM_130837.2:c.1870+1G>T,\N,\N,19/30,Likely pathogenic,Optic atrophy 1,splice_donor_variant,26.2,\N,\N,OPA1
609858,3:193364974:G>C,NM_130837.2:c.1870+5G>C,\N,\N,19/30,Unknown significance,\N,splice_region_variant&intron_variant,7.141,0.000226963,EVS_AA_AF,OPA1
609859,3:193364980:T>A,NM_130837.2:c.1870+11T>A,\N,\N,19/30,Unknown significance,\N,intron_variant,10.66,0.0029,1KG_AMR_AF,OPA1
609860,3:193364980:T>C,NM_130837.2:c.1870+11T>C,\N,\N,19/30,Unknown significance,\N,intron_variant,9.06,0.00158874,EVS_AA_AF,OPA1
609861,3:193364986:A>G,NM_130837.2:c.1870+17A>G,\N,\N,19/30,Unknown significance,\N,intron_variant,8.181,0.00147059,EXAC_OTH_AF,OPA1
609862,3:193365000:A>C,NM_130837.2:c.1870+31A>C,\N,\N,19/30,Unknown significance,\N,intron_variant,0.279,0.00162866,EXAC_OTH_AF,OPA1
609863,3:193365000:A>G,NM_130837.2:c.1870+31A>G,\N,\N,19/30,Unknown significance,\N,intron_variant,0.956,0.0000250138,EXAC_NFE_AF,OPA1
609864,3:193365006:AC>A,NM_130837.2:c.1870+38del,\N,\N,19/30,Unknown significance,\N,intron_variant,3.146,0.0029,1KG_AMR_AF,OPA1
609865,3:193365007:CATTTT>C,NM_130837.2:c.1870+42_1870+46del,\N,\N,19/30,Unknown significance,\N,intron_variant,8.169,0.000268097,EXAC_EAS_AF,OPA1
609866,3:193365008:A>G,NM_130837.2:c.1870+39A>G,\N,\N,19/30,Unknown significance,\N,intron_variant,3.547,0.0000279814,EXAC_NFE_AF,OPA1
609867,3:193365016:A>G,NM_130837.2:c.1870+47A>G,\N,\N,19/30,Unknown significance,\N,intron_variant,5.737,0.000128518,EXAC_NFE_AF,OPA1
609868,3:193365021:G>T,NM_130837.2:c.1870+52G>T,\N,\N,19/30,Unknown significance,\N,intron_variant,1.295,0.0008,1KG_AFR_AF,OPA1
609869,3:193365040:C>T,NM_130837.2:c.1870+71C>T,\N,\N,19/30,Unknown significance,\N,intron_variant,2.079,\N,\N,OPA1
609870,3:193365041:G>A,NM_130837.2:c.1870+72G>A,\N,\N,19/30,Unknown significance,\N,intron_variant,0.23,\N,\N,OPA1
609871,3:193365042:A>T,NM_130837.2:c.1870+73A>T,\N,\N,19/30,Unknown significance,\N,intron_variant,4.183,\N,\N,OPA1
609872,3:193365057:C>G,NM_130837.2:c.1870+88C>G,\N,\N,19/30,Unknown significance,\N,intron_variant,0.829,0.001,1KG_EUR_AF,OPA1
609873,3:193365152:T>C,NM_130837.2:c.1870+183T>C,\N,\N,19/30,Benign,\N,intron_variant,5.383,0.0199,1KG_EUR_AF,OPA1
609874,3:193365209:A>C,NM_130837.2:c.1870+240A>C,\N,\N,19/30,Unknown significance,\N,intron_variant,1.166,\N,\N,OPA1
609875,3:193365211:T>G,NM_130837.2:c.1870+242T>G,\N,\N,19/30,Unknown significance,\N,intron_variant,7.137,\N,\N,OPA1
609876,3:193365220:C>T,NM_130837.2:c.1870+251C>T,\N,\N,19/30,Unknown significance,\N,intron_variant,3.087,\N,\N,OPA1
609877,3:193365271:A>G,NM_130837.2:c.1870+302A>G,\N,\N,19/30,Unknown significance,\N,intron_variant,3.562,\N,\N,OPA1
609878,3:193365302:C>T,NM_130837.2:c.1870+333C>T,\N,\N,19/30,Unknown significance,\N,intron_variant,3.92,0.001,1KG_EAS_AF,OPA1
609879,3:193365310:C>A,NM_130837.2:c.1870+341C>A,\N,\N,19/30,Unknown significance,\N,intron_variant,2.62,0.001,1KG_SAS_AF,OPA1
609880,3:193365317:T>C,NM_130837.2:c.1870+348T>C,\N,\N,19/30,Unknown significance,\N,intron_variant,5.008,0.0014,1KG_AMR_AF,OPA1
609881,3:193365420:C>T,NM_130837.2:c.1871-439C>T,\N,\N,19/30,Benign,\N,intron_variant,12.76,0.0119,1KG_EUR_AF,OPA1
609882,3:193365456:TG>T,NM_130837.2:c.1871-402del,\N,\N,19/30,Unknown significance,\N,intron_variant,9.965,0.0029,1KG_AMR_AF,OPA1
609883,3:193365504:A>T,NM_130837.2:c.1871-355A>T,\N,\N,19/30,Unknown significance,\N,intron_variant,5.395,\N,\N,OPA1
609884,3:193365544:A>G,NM_130837.2:c.1871-315A>G,\N,\N,19/30,Benign,\N,intron_variant,5.779,0.4629,1KG_AFR_AF,OPA1
609885,3:193365572:G>A,NM_130837.2:c.1871-287G>A,\N,\N,19/30,Benign,\N,intron_variant,3.915,0.0189,1KG_AFR_AF,OPA1
609886,3:193365578:G>A,NM_130837.2:c.1871-281G>A,\N,\N,19/30,Unknown significance,\N,intron_variant,6.162,0.0008,1KG_AFR_AF,OPA1
609887,3:193365613:A>G,NM_130837.2:c.1871-246A>G,\N,\N,19/30,Benign,\N,intron_variant,1.062,0.0083,1KG_AFR_AF,OPA1
609888,3:193365621:A>G,NM_130837.2:c.1871-238A>G,\N,\N,19/30,Unknown significance,\N,intron_variant,3.51,\N,\N,OPA1
609889,3:193365635:G>C,NM_130837.2:c.1871-224G>C,\N,\N,19/30,Unknown significance,\N,intron_variant,9.18,0.0008,1KG_AFR_AF,OPA1
609890,3:193365693:A>G,NM_130837.2:c.1871-166A>G,\N,\N,19/30,Unknown significance,\N,intron_variant,7.151,0.003,1KG_EAS_AF,OPA1
609891,3:193365697:C>T,NM_130837.2:c.1871-162C>T,\N,\N,19/30,Benign,\N,intron_variant,10.89,0.0091,1KG_AFR_AF,OPA1
609892,3:193365717:G>A,NM_130837.2:c.1871-142G>A,\N,\N,19/30,Unknown significance,\N,intron_variant,4.462,\N,\N,OPA1
609893,3:193365745:T>C,NM_130837.2:c.1871-114T>C,\N,\N,19/30,Unknown significance,\N,intron_variant,1.148,\N,\N,OPA1
609894,3:193365749:C>T,NM_130837.2:c.1871-110C>T,\N,\N,19/30,Benign,\N,intron_variant,2.251,0.0367,1KG_EAS_AF,OPA1
609895,3:193365793:C>A,NM_130837.2:c.1871-66C>A,\N,\N,19/30,Benign,\N,intron_variant,6.055,0.0333,1KG_AFR_AF,OPA1
609896,3:193365808:C>T,NM_130837.2:c.1871-51C>T,\N,\N,19/30,Unknown significance,\N,intron_variant,5.629,0.000453926,EVS_AA_AF,OPA1
609897,3:193365821:G>A,NM_130837.2:c.1871-38G>A,\N,\N,19/30,Unknown significance,\N,intron_variant,9.914,0.000226963,EVS_AA_AF,OPA1
609898,3:193365839:A>C,NM_130837.2:c.1871-20A>C,\N,\N,19/30,Unknown significance,\N,intron_variant,10.95,0.0000152351,EXAC_NFE_AF,OPA1
609899,3:193365844:T>C,NM_130837.2:c.1871-15T>C,\N,\N,19/30,Unknown significance,\N,intron_variant,16.12,0.0000969932,EXAC_AFR_AF,OPA1
609900,3:193365848:T>G,NM_130837.2:c.1871-11T>G,\N,\N,19/30,Unknown significance,\N,intron_variant,18.76,0.0000616751,EXAC_SAS_AF,OPA1
609901,3:193365856:C>T,NM_130837.2:c.1871-3C>T,\N,\N,19/30,Unknown significance,\N,splice_region_variant&intron_variant,17.2,0.0000151021,EXAC_NFE_AF,OPA1
609902,3:193365858:G>A,NM_130837.2:c.1871-1G>A,\N,\N,19/30,Pathogenic,Optic atrophy 1,splice_acceptor_variant,27.1,\N,\N,OPA1
609903,3:193365864:C>T,NM_130837.2:c.1876C>T,NP_570850.2:p.Arg626Cys,20/31,\N,Unknown significance,\N,missense_variant,35,0.0000150652,EXAC_NFE_AF,OPA1
609904,3:193365865:G>A,NM_130837.2:c.1877G>A,NP_570850.2:p.Arg626His,20/31,\N,Pathogenic,Optic atrophy 1,missense_variant,35,0.000232558,EVS_EA_AF,OPA1
609905,3:193365874:T>C,NM_130837.2:c.1886T>C,NP_570850.2:p.Leu629Pro,20/31,\N,Pathogenic,Optic atrophy 1,missense_variant,29.6,\N,\N,OPA1
609906,3:193365876:G>A,NM_130837.2:c.1888G>A,NP_570850.2:p.Glu630Lys,20/31,\N,Unknown significance,\N,missense_variant,34,0.0000609013,EXAC_SAS_AF,OPA1
609907,3:193365876:GAA>G,NM_130837.2:c.1890_1891del,NP_570850.2:p.Glu630AspfsTer2,20/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,35,\N,\N,OPA1
609908,3:193365886:G>A,NM_130837.2:c.1898G>A,NP_570850.2:p.Trp633Ter,20/31,\N,Unknown significance,\N,stop_gained,39,\N,\N,OPA1
609909,3:193365898:A>G,NM_130837.2:c.1910A>G,NP_570850.2:p.Tyr637Cys,20/31,\N,Pathogenic,Progressive external ophthalmoplegia,missense_variant,26.6,\N,\N,OPA1
609910,3:193365903:C>T,NM_130837.2:c.1915C>T,NP_570850.2:p.Arg639Cys,20/31,\N,Unknown significance,\N,missense_variant,35,0.0000608421,EXAC_SAS_AF,OPA1
609911,3:193365904:G>A,NM_015560.2:c.1751G>A,NP_056375.2:p.Arg584His,18/29,\N,Unknown significance,\N,missense_variant,25.2,0.000116144,EXAC_EAS_AF,OPA1
609912,3:193365908:G>T,NM_130837.2:c.1920G>T,NP_570850.2:p.Leu640=,20/31,\N,Unknown significance,\N,synonymous_variant,8.307,0.0000150326,EXAC_NFE_AF,OPA1
609913,3:193365908:GCGGGAACTTGAC>G,NM_130837.2:c.1925_1935+1del,\N,20/31,\N,Pathogenic,Optic atrophy 1,inframe_deletion,22.4,\N,\N,OPA1
609914,3:193365921:C>T,NM_130837.2:c.1933C>T,NP_570850.2:p.Arg645Trp,20/31,\N,Pathogenic,Optic atrophy 1,missense_variant&splice_region_variant,34,0.0000451794,EXAC_NFE_AF,OPA1
609915,3:193365921:CG>C,NM_130837.2:c.1935+1del,\N,20/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant&splice_region_variant,35,\N,\N,OPA1
609916,3:193365922:G>A,NM_130837.2:c.1934G>A,NP_570850.2:p.Arg645Gln,20/31,\N,Pathogenic,Optic atrophy 1,missense_variant&splice_region_variant,35,0.000232558,EVS_EA_AF,OPA1
609917,3:193365923:G>A,NM_130837.2:c.1935G>A,NP_570850.2:p.Arg645=,20/31,\N,Pathogenic,Optic atrophy 1,splice_region_variant&synonymous_variant,15.24,\N,\N,OPA1
609918,3:193365923:G>C,NM_130837.2:c.1935G>C,NP_570850.2:p.Arg645=,20/31,\N,Pathogenic,Optic atrophy 1,splice_region_variant&synonymous_variant,14.04,\N,\N,OPA1
609919,3:193365923:G>T,NM_130837.2:c.1935G>T,NP_570850.2:p.Arg645=,20/31,\N,Pathogenic,Optic atrophy 1,splice_region_variant&synonymous_variant,14.67,\N,\N,OPA1
609920,3:193365925:T>C,NM_130837.2:c.1935+2T>C,\N,\N,20/30,Pathogenic,Optic atrophy 1,splice_donor_variant,24.9,\N,\N,OPA1
609921,3:193365926:A>G,NM_130837.2:c.1935+3A>G,\N,\N,20/30,Benign,\N,splice_region_variant&intron_variant,13.78,0.0000150839,EXAC_NFE_AF,OPA1
609922,3:193365929:A>AT,NM_130837.2:c.1935+9dup,\N,\N,20/30,Unknown significance,\N,splice_region_variant&intron_variant,2.537,0.00029098,EXAC_AFR_AF,OPA1
609923,3:193365930:T>C,NM_130837.2:c.1935+7T>C,\N,\N,20/30,Unknown significance,\N,splice_region_variant&intron_variant,5.685,0.000116279,EVS_EA_AF,OPA1
609924,3:193365938:C>T,NM_130837.2:c.1935+15C>T,\N,\N,20/30,Unknown significance,\N,intron_variant,4.751,0.0000977899,EXAC_AFR_AF,OPA1
609925,3:193365939:T>G,NM_130837.2:c.1935+16T>G,\N,\N,20/30,Benign,\N,intron_variant,4.791,0.1484,1KG_AMR_AF,OPA1
609926,3:193365940:C>T,NM_130837.2:c.1935+17C>T,\N,\N,20/30,Unknown significance,\N,intron_variant,2.885,0.0000152989,EXAC_NFE_AF,OPA1
609927,3:193365941:G>A,NM_130837.2:c.1935+18G>A,\N,\N,20/30,Unknown significance,\N,intron_variant,1.669,0.000196773,EXAC_AFR_AF,OPA1
609928,3:193365943:G>A,NM_130837.2:c.1935+20G>A,\N,\N,20/30,Unknown significance,\N,intron_variant,3.718,0.000235627,EXAC_EAS_AF,OPA1
609929,3:193365951:T>C,NM_130837.2:c.1935+28T>C,\N,\N,20/30,Unknown significance,\N,intron_variant,5.823,\N,\N,OPA1
609930,3:193365952:A>G,NM_130837.2:c.1935+29A>G,\N,\N,20/30,Unknown significance,\N,intron_variant,6.167,0.0000154521,EXAC_NFE_AF,OPA1
609931,3:193365956:A>T,NM_130837.2:c.1935+33A>T,\N,\N,20/30,Unknown significance,\N,intron_variant,1.766,0.0000154847,EXAC_NFE_AF,OPA1
609932,3:193365962:A>G,NM_130837.2:c.1935+39A>G,\N,\N,20/30,Unknown significance,\N,intron_variant,6.051,0.000714286,EXAC_EAS_AF,OPA1
609933,3:193365970:T>A,NM_130837.2:c.1935+47T>A,\N,\N,20/30,Benign,\N,intron_variant,4.666,0.0201613,EXAC_FIN_AF,OPA1
609934,3:193365974:T>A,NM_130837.2:c.1935+51T>A,\N,\N,20/30,Unknown significance,\N,intron_variant,6.09,0.00114943,EXAC_OTH_AF,OPA1
609935,3:193365974:T>G,NM_130837.2:c.1935+51T>G,\N,\N,20/30,Benign,\N,intron_variant,4.341,0.5862,1KG_AFR_AF,OPA1
609936,3:193365976:G>A,NM_130837.2:c.1935+53G>A,\N,\N,20/30,Unknown significance,\N,intron_variant,3.26,0.002,1KG_SAS_AF,OPA1
609937,3:193366010:A>G,NM_130837.2:c.1935+87A>G,\N,\N,20/30,Unknown significance,\N,intron_variant,0.565,\N,\N,OPA1
609938,3:193366035:A>G,NM_130837.2:c.1935+112A>G,\N,\N,20/30,Unknown significance,\N,intron_variant,2.499,0.0041,1KG_SAS_AF,OPA1
609939,3:193366059:A>C,NM_130837.2:c.1935+136A>C,\N,\N,20/30,Unknown significance,\N,intron_variant,2.646,0.001,1KG_SAS_AF,OPA1
609940,3:193366066:G>A,NM_130837.2:c.1935+143G>A,\N,\N,20/30,Unknown significance,\N,intron_variant,4.471,\N,\N,OPA1
609941,3:193366085:G>A,NM_130837.2:c.1935+162G>A,\N,\N,20/30,Unknown significance,\N,intron_variant,3.915,0.0014,1KG_AMR_AF,OPA1
609942,3:193366093:AATT>A,NM_130837.2:c.1935+174_1935+176del,\N,\N,20/30,Unknown significance,\N,intron_variant,4.683,\N,\N,OPA1
609943,3:193366094:ATTAT>A,NM_130837.2:c.1935+177_1935+180del,\N,\N,20/30,Benign,\N,intron_variant,7.741,0.0265,1KG_AFR_AF,OPA1
609944,3:193366116:A>C,NM_130837.2:c.1935+193A>C,\N,\N,20/30,Unknown significance,\N,intron_variant,0.77,0.001,1KG_EUR_AF,OPA1
609945,3:193366121:G>A,NM_130837.2:c.1935+198G>A,\N,\N,20/30,Unknown significance,\N,intron_variant,4.648,\N,\N,OPA1
609946,3:193366146:T>C,NM_130837.2:c.1935+223T>C,\N,\N,20/30,Unknown significance,\N,intron_variant,5.305,0.0014,1KG_AMR_AF,OPA1
609947,3:193366171:G>A,NM_130837.2:c.1935+248G>A,\N,\N,20/30,Unknown significance,\N,intron_variant,3.419,0.0008,1KG_AFR_AF,OPA1
609948,3:193366200:G>A,NM_130837.2:c.1935+277G>A,\N,\N,20/30,Unknown significance,\N,intron_variant,0.467,0.001,1KG_EAS_AF,OPA1
609949,3:193366204:A>G,NM_130837.2:c.1935+281A>G,\N,\N,20/30,Benign,\N,intron_variant,3.977,0.0779,1KG_AFR_AF,OPA1
609950,3:193366209:T>C,NM_130837.2:c.1935+286T>C,\N,\N,20/30,Unknown significance,\N,intron_variant,3.573,\N,\N,OPA1
609951,3:193366269:A>G,NM_130837.2:c.1936-315A>G,\N,\N,20/30,Unknown significance,\N,intron_variant,4.785,0.0015,1KG_AFR_AF,OPA1
609952,3:193366277:G>A,NM_130837.2:c.1936-307G>A,\N,\N,20/30,Unknown significance,\N,intron_variant,9.276,\N,\N,OPA1
609953,3:193366299:G>A,NM_130837.2:c.1936-285G>A,\N,\N,20/30,Unknown significance,\N,intron_variant,2.475,\N,\N,OPA1
609954,3:193366304:A>G,NM_130837.2:c.1936-280A>G,\N,\N,20/30,Unknown significance,\N,intron_variant,9.718,0.002,1KG_EUR_AF,OPA1
609955,3:193366330:A>G,NM_130837.2:c.1936-254A>G,\N,\N,20/30,Unknown significance,\N,intron_variant,0.945,0.0014,1KG_AMR_AF,OPA1
609956,3:193366334:C>T,NM_130837.2:c.1936-250C>T,\N,\N,20/30,Unknown significance,\N,intron_variant,2.844,0.0008,1KG_AFR_AF,OPA1
609957,3:193366372:G>GAA,NM_130837.2:c.1936-211_1936-210insAA,\N,\N,20/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
609958,3:193366380:A>G,NM_130837.2:c.1936-204A>G,\N,\N,20/30,Unknown significance,\N,intron_variant,14.67,\N,\N,OPA1
609959,3:193366389:T>C,NM_130837.2:c.1936-195T>C,\N,\N,20/30,Unknown significance,\N,intron_variant,16.51,0.002,1KG_SAS_AF,OPA1
609960,3:193366409:T>C,NM_130837.2:c.1936-175T>C,\N,\N,20/30,Unknown significance,\N,intron_variant,13.38,0.001,1KG_EUR_AF,OPA1
609961,3:193366412:G>A,NM_130837.2:c.1936-172G>A,\N,\N,20/30,Unknown significance,\N,intron_variant,13.85,\N,\N,OPA1
609962,3:193366422:A>G,NM_130837.2:c.1936-162A>G,\N,\N,20/30,Unknown significance,\N,intron_variant,13.14,0.003,1KG_AFR_AF,OPA1
609963,3:193366427:T>TA,NM_130837.2:c.1936-148dup,\N,\N,20/30,Unknown significance,\N,intron_variant,11.7,\N,\N,OPA1
609964,3:193366428:A>T,NM_130837.2:c.1936-156A>T,\N,\N,20/30,Benign,\N,intron_variant,10.76,0.0068,1KG_AFR_AF,OPA1
609965,3:193366451:T>A,NM_130837.2:c.1936-133T>A,\N,\N,20/30,Unknown significance,\N,intron_variant,8.63,0.001,1KG_EUR_AF,OPA1
609966,3:193366518:A>G,NM_130837.2:c.1936-66A>G,\N,\N,20/30,Unknown significance,\N,intron_variant,11.6,0.001,1KG_EUR_AF,OPA1
609967,3:193366528:C>G,NM_130837.2:c.1936-56C>G,\N,\N,20/30,Unknown significance,\N,intron_variant,8.594,\N,\N,OPA1
609968,3:193366530:G>A,NM_130837.2:c.1936-54G>A,\N,\N,20/30,Unknown significance,\N,intron_variant,8.532,\N,\N,OPA1
609969,3:193366530:G>C,NM_130837.2:c.1936-54G>C,\N,\N,20/30,Unknown significance,\N,intron_variant,6.122,\N,\N,OPA1
609970,3:193366549:T>C,NM_130837.2:c.1936-35T>C,\N,\N,20/30,Unknown significance,\N,intron_variant,4.018,0.000243043,EXAC_SAS_AF,OPA1
609971,3:193366555:TCTTA>T,NM_130837.2:c.1936-21_1936-18del,\N,\N,20/30,Unknown significance,\N,intron_variant,11.9,\N,\N,OPA1
609972,3:193366558:T>TA,NM_130837.2:c.1936-25dup,\N,\N,20/30,Unknown significance,\N,intron_variant,9.525,0.000060687,EXAC_SAS_AF,OPA1
609973,3:193366561:T>C,NM_130837.2:c.1936-23T>C,\N,\N,20/30,Unknown significance,\N,intron_variant,11.91,0.000100827,EXAC_AFR_AF,OPA1
609974,3:193366566:T>A,NM_130837.2:c.1936-18T>A,\N,\N,20/30,Unknown significance,\N,intron_variant,9.365,0.0000150399,EXAC_NFE_AF,OPA1
609975,3:193366569:A>G,NM_130837.2:c.1936-15A>G,\N,\N,20/30,Unknown significance,\N,intron_variant,1.514,0.001,1KG_EUR_AF,OPA1
609976,3:193366573:A>G,NM_130837.2:c.1936-11A>G,\N,\N,20/30,Unknown significance,\N,intron_variant,1.126,0.0008,1KG_AFR_AF,OPA1
609977,3:193366575:A>G,NM_130837.2:c.1936-9A>G,\N,\N,20/30,Unknown significance,\N,intron_variant,8.751,0.00181653,EVS_AA_AF,OPA1
609978,3:193366579:C>T,NM_130837.2:c.1936-5C>T,\N,\N,20/30,Unknown significance,\N,splice_region_variant&intron_variant,13.86,0.0000150263,EXAC_NFE_AF,OPA1
609979,3:193366582:A>G,NM_130837.2:c.1936-2A>G,\N,\N,20/30,Pathogenic,Optic atrophy 1,splice_acceptor_variant,25.5,0.0000994233,EXAC_AFR_AF,OPA1
609980,3:193366583:G>A,NM_130837.2:c.1936-1G>A,\N,\N,20/30,Pathogenic,Optic atrophy,splice_acceptor_variant,26.8,\N,\N,OPA1
609981,3:193366584:A>G,NM_130837.2:c.1936A>G,NP_570850.2:p.Asn646Asp,21/31,\N,Unknown significance,\N,missense_variant&splice_region_variant,12.31,0.000116414,EVS_EA_AF,OPA1
609982,3:193366588:AACT>A,NM_130837.2:c.1942_1944del,NP_570850.2:p.Leu648del,21/31,\N,Pathogenic,Optic atrophy,inframe_deletion,\N,\N,\N,OPA1
609983,3:193366590:C>T,NM_130837.2:c.1942C>T,NP_570850.2:p.Leu648=,21/31,\N,Unknown significance,\N,synonymous_variant,13.98,0.000227066,EVS_AA_AF,OPA1
609984,3:193366591:T>C,NM_130837.2:c.1943T>C,NP_570850.2:p.Leu648Pro,21/31,\N,Pathogenic,Optic atrophy 1,missense_variant,29.9,\N,\N,OPA1
609985,3:193366592:A>G,NM_130837.2:c.1944A>G,NP_570850.2:p.Leu648=,21/31,\N,Unknown significance,\N,synonymous_variant,5.427,0.0000606134,EXAC_SAS_AF,OPA1
609986,3:193366592:A>AT,NM_130837.2:c.1947dup,NP_570850.2:p.Glu650Ter,21/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,35,\N,\N,OPA1
609987,3:193366592:ATTTG>A,NM_130837.2:c.1945_1948del,NP_570850.2:p.Phe649LysfsTer14,21/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,35,\N,\N,OPA1
609988,3:193366600:A>G,NM_130837.2:c.1952A>G,NP_570850.2:p.Lys651Arg,21/31,\N,Unknown significance,\N,missense_variant,21.5,0.0000150105,EXAC_NFE_AF,OPA1
609989,3:193366604:T>A,NM_130837.2:c.1956T>A,NP_570850.2:p.Ala652=,21/31,\N,Unknown significance,\N,synonymous_variant,13.08,0.000116414,EVS_EA_AF,OPA1
609990,3:193366611:G>T,NM_130837.2:c.1963G>T,NP_570850.2:p.Glu655Ter,21/31,\N,Pathogenic,Optic atrophy 1,stop_gained,45,\N,\N,OPA1
609991,3:193366614:A>G,NM_130834.2:c.1855A>G,NP_570847.2:p.Ile619Val,20/30,\N,Unknown significance,\N,missense_variant,20.7,0.0000300138,EXAC_NFE_AF,OPA1
609992,3:193366620:G>C,NM_130837.2:c.1972G>C,NP_570850.2:p.Asp658His,21/31,\N,Pathogenic,Optic atrophy 1,missense_variant,32,\N,\N,OPA1
609993,3:193366635:C>T,NM_130837.2:c.1987C>T,NP_570850.2:p.Leu663=,21/31,\N,Unknown significance,\N,synonymous_variant,15.85,0.0000150087,EXAC_NFE_AF,OPA1
609994,3:193366642:A>G,NM_015560.2:c.1829A>G,NP_056375.2:p.Gln610Arg,19/29,\N,Unknown significance,\N,missense_variant,24.2,0.0000150101,EXAC_NFE_AF,OPA1
609995,3:193366644:G>A,NM_130837.2:c.1996G>A,NP_570850.2:p.Val666Ile,21/31,\N,Unknown significance,\N,missense_variant,22.8,0.001,1KG_EUR_AF,OPA1
609996,3:193366644:G>C,NM_130837.2:c.1996G>C,NP_570850.2:p.Val666Leu,21/31,\N,Unknown significance,\N,missense_variant,23.2,0.0000150105,EXAC_NFE_AF,OPA1
609997,3:193366645:TTACA>T,NM_130837.2:c.1998_2001del,NP_570850.2:p.Thr667GlnfsTer20,21/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,36,\N,\N,OPA1
609998,3:193366654:A>T,NM_130835.2:c.1898A>T,NP_570848.1:p.Lys633Ile,20/30,\N,Unknown significance,\N,missense_variant,24.7,0.000226963,EVS_AA_AF,OPA1
609999,3:193366659:TGGTAA>T,NM_130837.2:c.2012+1_2012+5del,\N,21/31,21/30,Pathogenic,Optic atrophy 1,splice_donor_variant&coding_sequence_variant&intron_variant,35,\N,\N,OPA1
610000,3:193366660:G>A,NM_130837.2:c.2012G>A,NP_570850.2:p.Trp671Ter,21/31,\N,Pathogenic,Optic atrophy 1,stop_gained&splice_region_variant,40,\N,\N,OPA1
610001,3:193366660:GGTAA>G,NM_130837.2:c.2012+4_2012+7del,\N,\N,21/30,Pathogenic,Optic atrophy 1,splice_donor_variant&intron_variant,28.7,\N,\N,OPA1
610002,3:193366661:G>C,NM_130837.2:c.2012+1G>C,\N,\N,21/30,Pathogenic,\N,splice_donor_variant,25.6,\N,\N,OPA1
610003,3:193366661:G>T,NM_130837.2:c.2012+1G>T,\N,\N,21/30,Pathogenic,Optic atrophy 1,splice_donor_variant,25.9,\N,\N,OPA1
610004,3:193366662:T>G,NM_130837.2:c.2012+2T>G,\N,\N,21/30,Pathogenic,Optic atrophy,splice_donor_variant,25.5,\N,\N,OPA1
610005,3:193366667:A>G,NM_130837.2:c.2012+7A>G,\N,\N,21/30,Unknown significance,\N,splice_region_variant&intron_variant,10.07,0.0000606502,EXAC_SAS_AF,OPA1
610006,3:193366671:G>A,NM_130837.2:c.2012+11G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,8.729,0.0000150236,EXAC_NFE_AF,OPA1
610007,3:193366680:C>G,NM_130837.2:c.2012+20C>G,\N,\N,21/30,Unknown significance,\N,intron_variant,2.291,0.0000974279,EXAC_AFR_AF,OPA1
610008,3:193366683:T>G,NM_130837.2:c.2012+23T>G,\N,\N,21/30,Unknown significance,\N,intron_variant,3.553,0.0000974849,EXAC_AFR_AF,OPA1
610009,3:193366688:T>C,NM_130837.2:c.2012+28T>C,\N,\N,21/30,Unknown significance,\N,intron_variant,3.021,0.0000150362,EXAC_NFE_AF,OPA1
610010,3:193366701:T>C,NM_130837.2:c.2012+41T>C,\N,\N,21/30,Unknown significance,\N,intron_variant,6.708,0.00181571,EVS_AA_AF,OPA1
610011,3:193366702:G>A,NM_130837.2:c.2012+42G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,0.027,0.000121389,EXAC_SAS_AF,OPA1
610012,3:193366705:C>G,NM_130837.2:c.2012+45C>G,\N,\N,21/30,Unknown significance,\N,intron_variant,1.345,0.0000150598,EXAC_NFE_AF,OPA1
610013,3:193366705:C>T,NM_130837.2:c.2012+45C>T,\N,\N,21/30,Unknown significance,\N,intron_variant,2.229,0.0014,1KG_AMR_AF,OPA1
610014,3:193366706:A>G,NM_130837.2:c.2012+46A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,1.281,0.0000150616,EXAC_NFE_AF,OPA1
610015,3:193366707:G>A,NM_130837.2:c.2012+47G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,3.367,0.0000150657,EXAC_NFE_AF,OPA1
610016,3:193366708:G>A,NM_130837.2:c.2012+48G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,6.169,0.0014,1KG_AMR_AF,OPA1
610017,3:193366725:A>C,NM_130837.2:c.2012+65A>C,\N,\N,21/30,Unknown significance,\N,intron_variant,2.755,\N,\N,OPA1
610018,3:193366758:G>A,NM_130837.2:c.2012+98G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,2.69,0.001,1KG_EAS_AF,OPA1
610019,3:193366760:C>G,NM_130837.2:c.2012+100C>G,\N,\N,21/30,Unknown significance,\N,intron_variant,5.417,0.0008,1KG_AFR_AF,OPA1
610020,3:193366765:C>T,NM_130837.2:c.2012+105C>T,\N,\N,21/30,Unknown significance,\N,intron_variant,5.835,0.0008,1KG_AFR_AF,OPA1
610021,3:193366779:C>T,NM_130837.2:c.2012+119C>T,\N,\N,21/30,Unknown significance,\N,intron_variant,3.922,\N,\N,OPA1
610022,3:193366789:TA>T,NM_130837.2:c.2012+130del,\N,\N,21/30,Unknown significance,\N,intron_variant,4.564,\N,\N,OPA1
610023,3:193366790:A>T,NM_130837.2:c.2012+130A>T,\N,\N,21/30,Unknown significance,\N,intron_variant,0.14,0.001,1KG_EAS_AF,OPA1
610024,3:193366858:C>A,NM_130837.2:c.2012+198C>A,\N,\N,21/30,Unknown significance,\N,intron_variant,7.355,\N,\N,OPA1
610025,3:193366887:A>G,NM_130837.2:c.2012+227A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,11.55,\N,\N,OPA1
610026,3:193366901:C>T,NM_130837.2:c.2012+241C>T,\N,\N,21/30,Unknown significance,\N,intron_variant,8.795,0.0008,1KG_AFR_AF,OPA1
610027,3:193366902:G>A,NM_130837.2:c.2012+242G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,8.285,\N,\N,OPA1
610028,3:193366904:A>C,NM_130837.2:c.2012+244A>C,\N,\N,21/30,Unknown significance,\N,intron_variant,7.486,\N,\N,OPA1
610029,3:193366937:G>GT,NM_130837.2:c.2012+281dup,\N,\N,21/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610030,3:193366956:T>C,NM_130837.2:c.2012+296T>C,\N,\N,21/30,Unknown significance,\N,intron_variant,2.591,0.004,1KG_EUR_AF,OPA1
610031,3:193366958:G>A,NM_130837.2:c.2012+298G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,3.415,\N,\N,OPA1
610032,3:193366969:A>G,NM_130837.2:c.2012+309A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,5.781,\N,\N,OPA1
610033,3:193366991:A>T,NM_130837.2:c.2012+331A>T,\N,\N,21/30,Unknown significance,\N,intron_variant,4.295,\N,\N,OPA1
610034,3:193366996:G>C,NM_130837.2:c.2012+336G>C,\N,\N,21/30,Benign,\N,intron_variant,0.202,0.0197,1KG_AFR_AF,OPA1
610035,3:193367054:CAT>C,NM_130837.2:c.2012+395_2012+396del,\N,\N,21/30,Unknown significance,\N,intron_variant,6.617,0.003,1KG_AFR_AF,OPA1
610036,3:193367080:T>C,NM_130837.2:c.2012+420T>C,\N,\N,21/30,Unknown significance,\N,intron_variant,8.7,0.001,1KG_EAS_AF,OPA1
610037,3:193367153:T>C,NM_130837.2:c.2012+493T>C,\N,\N,21/30,Unknown significance,\N,intron_variant,4.036,\N,\N,OPA1
610038,3:193367202:G>A,NM_130837.2:c.2012+542G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,8.504,0.001,1KG_SAS_AF,OPA1
610039,3:193367238:C>A,NM_130837.2:c.2012+578C>A,\N,\N,21/30,Unknown significance,\N,intron_variant,6.075,\N,\N,OPA1
610040,3:193367247:A>C,NM_130837.2:c.2012+587A>C,\N,\N,21/30,Unknown significance,\N,intron_variant,1.714,\N,\N,OPA1
610041,3:193367263:T>C,NM_130837.2:c.2012+603T>C,\N,\N,21/30,Benign,\N,intron_variant,5.295,0.0257,1KG_AFR_AF,OPA1
610042,3:193367272:C>T,NM_130837.2:c.2012+612C>T,\N,\N,21/30,Unknown significance,\N,intron_variant,7.401,0.0008,1KG_AFR_AF,OPA1
610043,3:193367328:A>G,NM_130837.2:c.2012+668A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,4.669,\N,\N,OPA1
610044,3:193367335:CTG>C,NM_130837.2:c.2012+678_2012+679del,\N,\N,21/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610045,3:193367373:A>G,NM_130837.2:c.2012+713A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,7.756,0.001,1KG_EUR_AF,OPA1
610046,3:193367452:A>G,NM_130837.2:c.2012+792A>G,\N,\N,21/30,Benign,\N,intron_variant,3.2,0.0265,1KG_AFR_AF,OPA1
610047,3:193367478:C>G,NM_130837.2:c.2012+818C>G,\N,\N,21/30,Unknown significance,\N,intron_variant,1.353,0.0008,1KG_AFR_AF,OPA1
610048,3:193367501:C>T,NM_130837.2:c.2012+841C>T,\N,\N,21/30,Unknown significance,\N,intron_variant,2.49,\N,\N,OPA1
610049,3:193367519:A>G,NM_130837.2:c.2012+859A>G,\N,\N,21/30,Benign,\N,intron_variant,5.055,0.1256,1KG_AFR_AF,OPA1
610050,3:193367537:A>G,NM_130837.2:c.2012+877A>G,\N,\N,21/30,Benign,\N,intron_variant,1.702,0.5877,1KG_AFR_AF,OPA1
610051,3:193367574:C>G,NM_130837.2:c.2012+914C>G,\N,\N,21/30,Unknown significance,\N,intron_variant,1.205,\N,\N,OPA1
610052,3:193367574:C>T,NM_130837.2:c.2012+914C>T,\N,\N,21/30,Unknown significance,\N,intron_variant,2.39,\N,\N,OPA1
610053,3:193367598:C>A,NM_130837.2:c.2012+938C>A,\N,\N,21/30,Unknown significance,\N,intron_variant,5.929,0.0014,1KG_AMR_AF,OPA1
610054,3:193367600:A>G,NM_130837.2:c.2012+940A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,1.254,\N,\N,OPA1
610055,3:193367721:T>A,NM_130837.2:c.2012+1061T>A,\N,\N,21/30,Unknown significance,\N,intron_variant,1.507,0.001,1KG_SAS_AF,OPA1
610056,3:193367750:G>C,NM_130837.2:c.2012+1090G>C,\N,\N,21/30,Unknown significance,\N,intron_variant,1.289,0.002,1KG_EAS_AF,OPA1
610057,3:193367783:G>A,NM_130837.2:c.2012+1123G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,2.044,0.001,1KG_EUR_AF,OPA1
610058,3:193367792:A>T,NM_130837.2:c.2012+1132A>T,\N,\N,21/30,Benign,\N,intron_variant,0.753,0.0051,1KG_SAS_AF,OPA1
610059,3:193367814:C>T,NM_130837.2:c.2012+1154C>T,\N,\N,21/30,Unknown significance,\N,intron_variant,1.183,\N,\N,OPA1
610060,3:193367836:G>T,NM_130837.2:c.2012+1176G>T,\N,\N,21/30,Unknown significance,\N,intron_variant,0.517,0.0043,1KG_AMR_AF,OPA1
610061,3:193367845:G>A,NM_130837.2:c.2012+1185G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,2.116,0.0038,1KG_AFR_AF,OPA1
610062,3:193367851:C>T,NM_130837.2:c.2012+1191C>T,\N,\N,21/30,Unknown significance,\N,intron_variant,2.916,0.001,1KG_SAS_AF,OPA1
610063,3:193367853:A>G,NM_130837.2:c.2012+1193A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,3.313,0.0041,1KG_SAS_AF,OPA1
610064,3:193367912:C>G,NM_130837.2:c.2012+1252C>G,\N,\N,21/30,Unknown significance,\N,intron_variant,1.007,\N,\N,OPA1
610065,3:193367922:A>T,NM_130837.2:c.2012+1262A>T,\N,\N,21/30,Unknown significance,\N,intron_variant,1.822,0.002,1KG_EAS_AF,OPA1
610066,3:193367972:A>G,NM_130837.2:c.2012+1312A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,1.614,\N,\N,OPA1
610067,3:193368020:C>T,NM_130837.2:c.2012+1360C>T,\N,\N,21/30,Unknown significance,\N,intron_variant,5.645,\N,\N,OPA1
610068,3:193368022:G>T,NM_130837.2:c.2012+1362G>T,\N,\N,21/30,Unknown significance,\N,intron_variant,1.961,0.0043,1KG_AMR_AF,OPA1
610069,3:193368027:C>T,NM_130837.2:c.2012+1367C>T,\N,\N,21/30,Unknown significance,\N,intron_variant,3.366,\N,\N,OPA1
610070,3:193368039:G>A,NM_130837.2:c.2012+1379G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,6.203,\N,\N,OPA1
610071,3:193368052:C>A,NM_130837.2:c.2012+1392C>A,\N,\N,21/30,Unknown significance,\N,intron_variant,4.829,\N,\N,OPA1
610072,3:193368093:C>T,NM_130837.2:c.2012+1433C>T,\N,\N,21/30,Unknown significance,\N,intron_variant,0.907,\N,\N,OPA1
610073,3:193368094:G>A,NM_130837.2:c.2012+1434G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,1.269,\N,\N,OPA1
610074,3:193368121:A>G,NM_130837.2:c.2012+1461A>G,\N,\N,21/30,Benign,\N,intron_variant,5.318,0.0242,1KG_AFR_AF,OPA1
610075,3:193368154:G>A,NM_130837.2:c.2012+1494G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,6.78,0.0031,1KG_SAS_AF,OPA1
610076,3:193368170:G>A,NM_130837.2:c.2012+1510G>A,\N,\N,21/30,Benign,\N,intron_variant,6.966,0.0265,1KG_AFR_AF,OPA1
610077,3:193368190:C>T,NM_130837.2:c.2012+1530C>T,\N,\N,21/30,Unknown significance,\N,intron_variant,7.299,0.001,1KG_SAS_AF,OPA1
610078,3:193368225:C>T,NM_130837.2:c.2012+1565C>T,\N,\N,21/30,Unknown significance,\N,intron_variant,3.086,\N,\N,OPA1
610079,3:193368238:C>T,NM_130837.2:c.2012+1578C>T,\N,\N,21/30,Unknown significance,\N,intron_variant,2.856,\N,\N,OPA1
610080,3:193368304:A>G,NM_130837.2:c.2012+1644A>G,\N,\N,21/30,Benign,\N,intron_variant,1.758,0.0265,1KG_AFR_AF,OPA1
610081,3:193368339:A>G,NM_130837.2:c.2012+1679A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,0.942,0.001,1KG_SAS_AF,OPA1
610082,3:193368392:G>T,NM_130837.2:c.2012+1732G>T,\N,\N,21/30,Unknown significance,\N,intron_variant,0.465,0.003,1KG_EAS_AF,OPA1
610083,3:193368413:T>A,NM_130837.2:c.2012+1753T>A,\N,\N,21/30,Unknown significance,\N,intron_variant,7.768,\N,\N,OPA1
610084,3:193368427:A>T,NM_130837.2:c.2012+1767A>T,\N,\N,21/30,Unknown significance,\N,intron_variant,1.4,0.001,1KG_EUR_AF,OPA1
610085,3:193368476:G>A,NM_130837.2:c.2012+1816G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,2.281,0.001,1KG_EAS_AF,OPA1
610086,3:193368536:G>A,NM_130837.2:c.2012+1876G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,2.335,\N,\N,OPA1
610087,3:193368545:C>T,NM_130837.2:c.2012+1885C>T,\N,\N,21/30,Unknown significance,\N,intron_variant,1.445,\N,\N,OPA1
610088,3:193368549:G>A,NM_130837.2:c.2012+1889G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,1.463,0.003,1KG_EUR_AF,OPA1
610089,3:193368567:T>C,NM_130837.2:c.2012+1907T>C,\N,\N,21/30,Unknown significance,\N,intron_variant,2.632,\N,\N,OPA1
610090,3:193368599:A>G,NM_130837.2:c.2012+1939A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,1.345,\N,\N,OPA1
610091,3:193368613:A>G,NM_130837.2:c.2012+1953A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,8.708,\N,\N,OPA1
610092,3:193368625:A>G,NM_130837.2:c.2012+1965A>G,\N,\N,21/30,Benign,\N,intron_variant,3.484,0.006,1KG_EUR_AF,OPA1
610093,3:193368642:C>A,NM_130837.2:c.2012+1982C>A,\N,\N,21/30,Benign,\N,intron_variant,3.829,0.0238,1KG_EAS_AF,OPA1
610094,3:193368692:C>A,NM_130837.2:c.2012+2032C>A,\N,\N,21/30,Benign,\N,intron_variant,0.306,0.4264,1KG_EUR_AF,OPA1
610095,3:193368700:G>A,NM_130837.2:c.2012+2040G>A,\N,\N,21/30,Benign,\N,intron_variant,0.603,0.4264,1KG_EUR_AF,OPA1
610096,3:193368702:A>G,NM_130837.2:c.2012+2042A>G,\N,\N,21/30,Benign,\N,intron_variant,3.923,0.0121,1KG_AFR_AF,OPA1
610097,3:193368719:C>T,NM_130837.2:c.2012+2059C>T,\N,\N,21/30,Unknown significance,\N,intron_variant,1.549,0.001,1KG_SAS_AF,OPA1
610098,3:193368769:A>G,NM_130837.2:c.2012+2109A>G,\N,\N,21/30,Benign,\N,intron_variant,0.71,0.0119,1KG_EAS_AF,OPA1
610099,3:193368774:T>G,NM_130837.2:c.2012+2114T>G,\N,\N,21/30,Unknown significance,\N,intron_variant,14.1,\N,\N,OPA1
610100,3:193368777:G>A,NM_130837.2:c.2012+2117G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,15.34,\N,\N,OPA1
610101,3:193368804:A>G,NM_130837.2:c.2012+2144A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,6.774,\N,\N,OPA1
610102,3:193368812:C>T,NM_130837.2:c.2012+2152C>T,\N,\N,21/30,Unknown significance,\N,intron_variant,4.431,0.004,1KG_EAS_AF,OPA1
610103,3:193368813:G>A,NM_130837.2:c.2012+2153G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,3.603,0.001,1KG_SAS_AF,OPA1
610104,3:193368814:A>C,NM_130837.2:c.2012+2154A>C,\N,\N,21/30,Unknown significance,\N,intron_variant,2.812,\N,\N,OPA1
610105,3:193368831:G>A,NM_130837.2:c.2012+2171G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,4.484,0.001,1KG_EAS_AF,OPA1
610106,3:193368833:G>A,NM_130837.2:c.2012+2173G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,1.306,0.003,1KG_AFR_AF,OPA1
610107,3:193368834:A>G,NM_130837.2:c.2012+2174A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,2.498,\N,\N,OPA1
610108,3:193368838:A>AG,NM_130837.2:c.2012+2180dup,\N,\N,21/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610109,3:193368874:G>T,NM_130837.2:c.2012+2214G>T,\N,\N,21/30,Unknown significance,\N,intron_variant,0.912,0.003,1KG_EAS_AF,OPA1
610110,3:193368901:T>A,NM_130837.2:c.2012+2241T>A,\N,\N,21/30,Unknown significance,\N,intron_variant,4.081,0.001,1KG_SAS_AF,OPA1
610111,3:193368971:G>C,NM_130837.2:c.2012+2311G>C,\N,\N,21/30,Unknown significance,\N,intron_variant,0.579,0.001,1KG_EUR_AF,OPA1
610112,3:193369030:C>A,NM_130837.2:c.2012+2370C>A,\N,\N,21/30,Unknown significance,\N,intron_variant,2.149,\N,\N,OPA1
610113,3:193369031:A>G,NM_130837.2:c.2012+2371A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,3.138,\N,\N,OPA1
610114,3:193369043:A>G,NM_130837.2:c.2012+2383A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,0.21,\N,\N,OPA1
610115,3:193369046:C>T,NM_130837.2:c.2012+2386C>T,\N,\N,21/30,Unknown significance,\N,intron_variant,1.617,\N,\N,OPA1
610116,3:193369064:A>G,NM_130837.2:c.2012+2404A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,1.902,0.001,1KG_SAS_AF,OPA1
610117,3:193369065:G>A,NM_130837.2:c.2012+2405G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,4.083,0.001,1KG_SAS_AF,OPA1
610118,3:193369102:T>C,NM_130837.2:c.2012+2442T>C,\N,\N,21/30,Unknown significance,\N,intron_variant,2.643,0.001,1KG_EAS_AF,OPA1
610119,3:193369124:A>G,NM_130837.2:c.2012+2464A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,0.786,\N,\N,OPA1
610120,3:193369183:AAGAT>A,NM_130837.2:c.2012+2527_2012+2530del,\N,\N,21/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610121,3:193369200:A>T,NM_130837.2:c.2012+2540A>T,\N,\N,21/30,Benign,\N,intron_variant,1.51,0.0367,1KG_EAS_AF,OPA1
610122,3:193369217:A>C,NM_130837.2:c.2012+2557A>C,\N,\N,21/30,Unknown significance,\N,intron_variant,0.336,\N,\N,OPA1
610123,3:193369245:A>G,NM_130837.2:c.2012+2585A>G,\N,\N,21/30,Benign,\N,intron_variant,2.006,0.0179,1KG_EAS_AF,OPA1
610124,3:193369285:A>G,NM_130837.2:c.2012+2625A>G,\N,\N,21/30,Benign,\N,intron_variant,0.976,0.1248,1KG_AFR_AF,OPA1
610125,3:193369356:G>A,NM_130837.2:c.2012+2696G>A,\N,\N,21/30,Benign,\N,intron_variant,2.453,0.0367,1KG_EAS_AF,OPA1
610126,3:193369463:A>G,NM_130837.2:c.2012+2803A>G,\N,\N,21/30,Benign,\N,intron_variant,0.894,0.4284,1KG_EUR_AF,OPA1
610127,3:193369517:G>A,NM_130837.2:c.2012+2857G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,0.102,\N,\N,OPA1
610128,3:193369520:T>G,NM_130837.2:c.2012+2860T>G,\N,\N,21/30,Unknown significance,\N,intron_variant,3.067,\N,\N,OPA1
610129,3:193369524:T>A,NM_130837.2:c.2012+2864T>A,\N,\N,21/30,Benign,\N,intron_variant,3.294,0.4284,1KG_EUR_AF,OPA1
610130,3:193369563:C>T,NM_130837.2:c.2012+2903C>T,\N,\N,21/30,Benign,\N,intron_variant,0.16,0.0417,1KG_EUR_AF,OPA1
610131,3:193369580:T>A,NM_130837.2:c.2012+2920T>A,\N,\N,21/30,Unknown significance,\N,intron_variant,0.061,\N,\N,OPA1
610132,3:193369610:TATAAA>T,NM_130837.2:c.2012+2952_2012+2956del,\N,\N,21/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610133,3:193369616:A>G,NM_130837.2:c.2012+2956A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,1.235,\N,\N,OPA1
610134,3:193369632:A>G,NM_130837.2:c.2012+2972A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,0.564,0.001,1KG_SAS_AF,OPA1
610135,3:193369678:A>C,NM_130837.2:c.2013-2973A>C,\N,\N,21/30,Benign,\N,intron_variant,1.077,0.0091,1KG_AFR_AF,OPA1
610136,3:193369685:T>A,NM_130837.2:c.2013-2966T>A,\N,\N,21/30,Benign,\N,intron_variant,5.505,0.062,1KG_AFR_AF,OPA1
610137,3:193369697:T>A,NM_130837.2:c.2013-2954T>A,\N,\N,21/30,Unknown significance,\N,intron_variant,5.383,\N,\N,OPA1
610138,3:193369697:TA>T,NM_130837.2:c.2013-2945del,\N,\N,21/30,Benign,\N,intron_variant,0.132,0.68,1KG_AFR_AF,OPA1
610139,3:193369706:A>T,NM_130837.2:c.2013-2945A>T,\N,\N,21/30,Unknown significance,\N,intron_variant,0.275,\N,\N,OPA1
610140,3:193369723:T>A,NM_130837.2:c.2013-2928T>A,\N,\N,21/30,Unknown significance,\N,intron_variant,5.338,\N,\N,OPA1
610141,3:193369727:A>G,NM_130837.2:c.2013-2924A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,1.322,\N,\N,OPA1
610142,3:193369739:T>G,NM_130837.2:c.2013-2912T>G,\N,\N,21/30,Unknown significance,\N,intron_variant,4.563,\N,\N,OPA1
610143,3:193369752:T>C,NM_130837.2:c.2013-2899T>C,\N,\N,21/30,Unknown significance,\N,intron_variant,0.637,0.0008,1KG_AFR_AF,OPA1
610144,3:193369774:A>G,NM_130837.2:c.2013-2877A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,3.247,\N,\N,OPA1
610145,3:193369838:T>A,NM_130837.2:c.2013-2813T>A,\N,\N,21/30,Unknown significance,\N,intron_variant,12.24,\N,\N,OPA1
610146,3:193369845:A>C,NM_130837.2:c.2013-2806A>C,\N,\N,21/30,Unknown significance,\N,intron_variant,7.344,\N,\N,OPA1
610147,3:193369868:C>G,NM_130837.2:c.2013-2783C>G,\N,\N,21/30,Unknown significance,\N,intron_variant,2.31,\N,\N,OPA1
610148,3:193369880:A>C,NM_130837.2:c.2013-2771A>C,\N,\N,21/30,Benign,\N,intron_variant,0.929,0.0068,1KG_AFR_AF,OPA1
610149,3:193369885:A>G,NM_130837.2:c.2013-2766A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,2.412,\N,\N,OPA1
610150,3:193369898:G>A,NM_130837.2:c.2013-2753G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,0.099,\N,\N,OPA1
610151,3:193369945:G>A,NM_130837.2:c.2013-2706G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,0.106,0.0008,1KG_AFR_AF,OPA1
610152,3:193369975:A>G,NM_130837.2:c.2013-2676A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,9.046,\N,\N,OPA1
610153,3:193369989:G>C,NM_130837.2:c.2013-2662G>C,\N,\N,21/30,Unknown significance,\N,intron_variant,3.669,0.001,1KG_SAS_AF,OPA1
610154,3:193369995:A>T,NM_130837.2:c.2013-2656A>T,\N,\N,21/30,Benign,\N,intron_variant,3.291,0.0086,1KG_AMR_AF,OPA1
610155,3:193369996:C>A,NM_130837.2:c.2013-2655C>A,\N,\N,21/30,Unknown significance,\N,intron_variant,5.896,0.001,1KG_SAS_AF,OPA1
610156,3:193370085:C>T,NM_130837.2:c.2013-2566C>T,\N,\N,21/30,Benign,\N,intron_variant,0.716,0.0079,1KG_EAS_AF,OPA1
610157,3:193370088:T>C,NM_130837.2:c.2013-2563T>C,\N,\N,21/30,Unknown significance,\N,intron_variant,2.207,0.0008,1KG_AFR_AF,OPA1
610158,3:193370103:G>A,NM_130837.2:c.2013-2548G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,1.273,0.002,1KG_EUR_AF,OPA1
610159,3:193370135:C>T,NM_130837.2:c.2013-2516C>T,\N,\N,21/30,Unknown significance,\N,intron_variant,4.699,0.0008,1KG_AFR_AF,OPA1
610160,3:193370152:C>T,NM_130837.2:c.2013-2499C>T,\N,\N,21/30,Benign,\N,intron_variant,3.654,0.0268,1KG_EUR_AF,OPA1
610161,3:193370162:C>T,NM_130837.2:c.2013-2489C>T,\N,\N,21/30,Unknown significance,\N,intron_variant,5.062,\N,\N,OPA1
610162,3:193370168:C>G,NM_130837.2:c.2013-2483C>G,\N,\N,21/30,Unknown significance,\N,intron_variant,3.964,\N,\N,OPA1
610163,3:193370179:C>A,NM_130837.2:c.2013-2472C>A,\N,\N,21/30,Unknown significance,\N,intron_variant,0.939,\N,\N,OPA1
610164,3:193370183:C>A,NM_130837.2:c.2013-2468C>A,\N,\N,21/30,Benign,\N,intron_variant,0.387,0.3383,1KG_EAS_AF,OPA1
610165,3:193370183:C>CA,NM_130837.2:c.2013-2456dup,\N,\N,21/30,Unknown significance,\N,intron_variant,0.408,\N,\N,OPA1
610166,3:193370183:CAA>C,NM_130837.2:c.2013-2457_2013-2456del,\N,\N,21/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610167,3:193370186:A>AC,NM_130837.2:c.2013-2465_2013-2464insC,\N,\N,21/30,Benign,\N,intron_variant,0.023,0.0053,1KG_AFR_AF,OPA1
610168,3:193370187:A>C,NM_130837.2:c.2013-2464A>C,\N,\N,21/30,Benign,\N,intron_variant,0.064,0.1286,1KG_AFR_AF,OPA1
610169,3:193370195:A>C,NM_130837.2:c.2013-2456A>C,\N,\N,21/30,Unknown significance,\N,intron_variant,0.349,\N,\N,OPA1
610170,3:193370208:G>C,NM_130837.2:c.2013-2443G>C,\N,\N,21/30,Unknown significance,\N,intron_variant,0.585,0.0008,1KG_AFR_AF,OPA1
610171,3:193370215:A>T,NM_130837.2:c.2013-2436A>T,\N,\N,21/30,Unknown significance,\N,intron_variant,0.77,0.0023,1KG_AFR_AF,OPA1
610172,3:193370250:G>T,NM_130837.2:c.2013-2401G>T,\N,\N,21/30,Unknown significance,\N,intron_variant,1.34,0.001,1KG_EAS_AF,OPA1
610173,3:193370277:T>G,NM_130837.2:c.2013-2374T>G,\N,\N,21/30,Benign,\N,intron_variant,3.238,0.0053,1KG_AFR_AF,OPA1
610174,3:193370299:A>G,NM_130837.2:c.2013-2352A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,1.461,\N,\N,OPA1
610175,3:193370310:G>A,NM_130837.2:c.2013-2341G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,3.292,\N,\N,OPA1
610176,3:193370352:A>AC,NM_130837.2:c.2013-2298dup,\N,\N,21/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610177,3:193370352:A>G,NM_130837.2:c.2013-2299A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,3.659,0.0008,1KG_AFR_AF,OPA1
610178,3:193370356:C>T,NM_130837.2:c.2013-2295C>T,\N,\N,21/30,Unknown significance,\N,intron_variant,5.048,\N,\N,OPA1
610179,3:193370366:A>G,NM_130837.2:c.2013-2285A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,4.165,0.0008,1KG_AFR_AF,OPA1
610180,3:193370369:C>G,NM_130837.2:c.2013-2282C>G,\N,\N,21/30,Unknown significance,\N,intron_variant,2.629,0.0014,1KG_AMR_AF,OPA1
610181,3:193370435:T>A,NM_130837.2:c.2013-2216T>A,\N,\N,21/30,Benign,\N,intron_variant,4.915,0.0303,1KG_AFR_AF,OPA1
610182,3:193370439:T>A,NM_130837.2:c.2013-2212T>A,\N,\N,21/30,Unknown significance,\N,intron_variant,3.152,\N,\N,OPA1
610183,3:193370441:A>C,NM_130837.2:c.2013-2210A>C,\N,\N,21/30,Benign,\N,intron_variant,2.785,0.0179,1KG_EAS_AF,OPA1
610184,3:193370455:G>A,NM_130837.2:c.2013-2196G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,3.999,0.003,1KG_AFR_AF,OPA1
610185,3:193370458:A>G,NM_130837.2:c.2013-2193A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,3.076,\N,\N,OPA1
610186,3:193370459:A>G,NM_130837.2:c.2013-2192A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,2.057,0.0031,1KG_SAS_AF,OPA1
610187,3:193370538:G>A,NM_130837.2:c.2013-2113G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,3.23,\N,\N,OPA1
610188,3:193370607:G>A,NM_130837.2:c.2013-2044G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,2.844,\N,\N,OPA1
610189,3:193370612:G>A,NM_130837.2:c.2013-2039G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,4.329,\N,\N,OPA1
610190,3:193370640:T>C,NM_130837.2:c.2013-2011T>C,\N,\N,21/30,Unknown significance,\N,intron_variant,1.421,\N,\N,OPA1
610191,3:193370680:T>G,NM_130837.2:c.2013-1971T>G,\N,\N,21/30,Unknown significance,\N,intron_variant,5.36,\N,\N,OPA1
610192,3:193370693:G>A,NM_130837.2:c.2013-1958G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,4.105,0.002,1KG_EUR_AF,OPA1
610193,3:193370700:G>A,NM_130837.2:c.2013-1951G>A,\N,\N,21/30,Benign,\N,intron_variant,6.456,0.0432,1KG_AMR_AF,OPA1
610194,3:193370718:C>G,NM_130837.2:c.2013-1933C>G,\N,\N,21/30,Unknown significance,\N,intron_variant,4.108,\N,\N,OPA1
610195,3:193370719:A>AG,NM_130837.2:c.2013-1929dup,\N,\N,21/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610196,3:193370746:T>C,NM_130837.2:c.2013-1905T>C,\N,\N,21/30,Unknown significance,\N,intron_variant,4.738,\N,\N,OPA1
610197,3:193370775:T>A,NM_130837.2:c.2013-1876T>A,\N,\N,21/30,Benign,\N,intron_variant,6.133,0.062,1KG_AFR_AF,OPA1
610198,3:193370784:G>C,NM_130837.2:c.2013-1867G>C,\N,\N,21/30,Unknown significance,\N,intron_variant,0.606,\N,\N,OPA1
610199,3:193370786:A>T,NM_130837.2:c.2013-1865A>T,\N,\N,21/30,Unknown significance,\N,intron_variant,2.141,0.001,1KG_EUR_AF,OPA1
610200,3:193370824:G>A,NM_130837.2:c.2013-1827G>A,\N,\N,21/30,Benign,\N,intron_variant,3.269,0.0069,1KG_EAS_AF,OPA1
610201,3:193370846:ATCT>A,NM_130837.2:c.2013-1800_2013-1798del,\N,\N,21/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610202,3:193370942:A>G,NM_130837.2:c.2013-1709A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,12.66,0.001,1KG_SAS_AF,OPA1
610203,3:193370943:T>C,NM_130837.2:c.2013-1708T>C,\N,\N,21/30,Unknown significance,\N,intron_variant,11.9,\N,\N,OPA1
610204,3:193370954:AC>A,NM_130837.2:c.2013-1696del,\N,\N,21/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610205,3:193370971:CT>C,NM_130837.2:c.2013-1676del,\N,\N,21/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610206,3:193370992:T>C,NM_130837.2:c.2013-1659T>C,\N,\N,21/30,Unknown significance,\N,intron_variant,3.761,\N,\N,OPA1
610207,3:193371036:G>A,NM_130837.2:c.2013-1615G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,0.822,0.0014,1KG_AMR_AF,OPA1
610208,3:193371082:C>G,NM_130837.2:c.2013-1569C>G,\N,\N,21/30,Unknown significance,\N,intron_variant,1.678,0.0015,1KG_AFR_AF,OPA1
610209,3:193371084:G>A,NM_130837.2:c.2013-1567G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,1.843,0.0014,1KG_AMR_AF,OPA1
610210,3:193371092:A>G,NM_130837.2:c.2013-1559A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,2.409,\N,\N,OPA1
610211,3:193371097:TA>T,NM_130837.2:c.2013-1553del,\N,\N,21/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610212,3:193371186:A>G,NM_130837.2:c.2013-1465A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,4.596,0.0029,1KG_AMR_AF,OPA1
610213,3:193371267:T>G,NM_130837.2:c.2013-1384T>G,\N,\N,21/30,Unknown significance,\N,intron_variant,2.088,\N,\N,OPA1
610214,3:193371285:G>C,NM_130837.2:c.2013-1366G>C,\N,\N,21/30,Unknown significance,\N,intron_variant,7.527,0.0014,1KG_AMR_AF,OPA1
610215,3:193371347:T>G,NM_130837.2:c.2013-1304T>G,\N,\N,21/30,Unknown significance,\N,intron_variant,10.4,0.001,1KG_EAS_AF,OPA1
610216,3:193371352:T>A,NM_130837.2:c.2013-1299T>A,\N,\N,21/30,Unknown significance,\N,intron_variant,3.931,0.001,1KG_EAS_AF,OPA1
610217,3:193371354:T>G,NM_130837.2:c.2013-1297T>G,\N,\N,21/30,Unknown significance,\N,intron_variant,4.762,0.001,1KG_EUR_AF,OPA1
610218,3:193371362:C>T,NM_130837.2:c.2013-1289C>T,\N,\N,21/30,Unknown significance,\N,intron_variant,3.017,0.001,1KG_EAS_AF,OPA1
610219,3:193371363:C>T,NM_130837.2:c.2013-1288C>T,\N,\N,21/30,Benign,\N,intron_variant,1.999,0.0179,1KG_EAS_AF,OPA1
610220,3:193371406:A>G,NM_130837.2:c.2013-1245A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,4.573,0.001,1KG_EAS_AF,OPA1
610221,3:193371413:A>G,NM_130837.2:c.2013-1238A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,4.901,\N,\N,OPA1
610222,3:193371448:A>G,NM_130837.2:c.2013-1203A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,3.51,\N,\N,OPA1
610223,3:193371629:C>T,NM_130837.2:c.2013-1022C>T,\N,\N,21/30,Unknown significance,\N,intron_variant,0.691,0.0031,1KG_SAS_AF,OPA1
610224,3:193371650:A>G,NM_130837.2:c.2013-1001A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,2.298,0.001,1KG_EUR_AF,OPA1
610225,3:193371653:A>C,NM_130837.2:c.2013-998A>C,\N,\N,21/30,Unknown significance,\N,intron_variant,0.647,0.0029,1KG_AMR_AF,OPA1
610226,3:193371657:T>C,NM_130837.2:c.2013-994T>C,\N,\N,21/30,Benign,\N,intron_variant,2.714,0.0091,1KG_AFR_AF,OPA1
610227,3:193371660:T>A,NM_130837.2:c.2013-991T>A,\N,\N,21/30,Unknown significance,\N,intron_variant,1.365,\N,\N,OPA1
610228,3:193371691:T>A,NM_130837.2:c.2013-960T>A,\N,\N,21/30,Unknown significance,\N,intron_variant,3.75,\N,\N,OPA1
610229,3:193371691:T>G,NM_130837.2:c.2013-960T>G,\N,\N,21/30,Unknown significance,\N,intron_variant,2.364,\N,\N,OPA1
610230,3:193371693:C>G,NM_130837.2:c.2013-958C>G,\N,\N,21/30,Benign,\N,intron_variant,6.311,0.4294,1KG_EUR_AF,OPA1
610231,3:193371702:G>A,NM_130837.2:c.2013-949G>A,\N,\N,21/30,Benign,\N,intron_variant,7.938,0.0257,1KG_AFR_AF,OPA1
610232,3:193371723:G>A,NM_130837.2:c.2013-928G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,1.969,\N,\N,OPA1
610233,3:193371742:G>A,NM_130837.2:c.2013-909G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,1.034,\N,\N,OPA1
610234,3:193371749:T>A,NM_130837.2:c.2013-902T>A,\N,\N,21/30,Benign,\N,intron_variant,7.467,0.0053,1KG_AFR_AF,OPA1
610235,3:193371784:A>G,NM_130837.2:c.2013-867A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,4.84,\N,\N,OPA1
610236,3:193371800:T>C,NM_130837.2:c.2013-851T>C,\N,\N,21/30,Benign,\N,intron_variant,1.312,0.0053,1KG_AFR_AF,OPA1
610237,3:193371816:C>T,NM_130837.2:c.2013-835C>T,\N,\N,21/30,Unknown significance,\N,intron_variant,3.932,0.001,1KG_EAS_AF,OPA1
610238,3:193371818:C>G,NM_130837.2:c.2013-833C>G,\N,\N,21/30,Unknown significance,\N,intron_variant,2.371,0.0029,1KG_AMR_AF,OPA1
610239,3:193371822:G>C,NM_130837.2:c.2013-829G>C,\N,\N,21/30,Benign,\N,intron_variant,0.383,0.0053,1KG_AFR_AF,OPA1
610240,3:193371840:A>G,NM_130837.2:c.2013-811A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,3.561,\N,\N,OPA1
610241,3:193371865:A>T,NM_130837.2:c.2013-786A>T,\N,\N,21/30,Benign,\N,intron_variant,1.089,0.0106,1KG_AFR_AF,OPA1
610242,3:193371889:G>C,NM_130837.2:c.2013-762G>C,\N,\N,21/30,Unknown significance,\N,intron_variant,0.059,0.001,1KG_EUR_AF,OPA1
610243,3:193371899:T>C,NM_130837.2:c.2013-752T>C,\N,\N,21/30,Unknown significance,\N,intron_variant,3.277,\N,\N,OPA1
610244,3:193371925:A>G,NM_130837.2:c.2013-726A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,1.116,0.0015,1KG_AFR_AF,OPA1
610245,3:193371948:G>C,NM_130837.2:c.2013-703G>C,\N,\N,21/30,Benign,\N,intron_variant,0.735,0.0367,1KG_EAS_AF,OPA1
610246,3:193371954:C>T,NM_130837.2:c.2013-697C>T,\N,\N,21/30,Unknown significance,\N,intron_variant,4.261,\N,\N,OPA1
610247,3:193371964:C>A,NM_130837.2:c.2013-687C>A,\N,\N,21/30,Benign,\N,intron_variant,3.74,0.005,1KG_EAS_AF,OPA1
610248,3:193372012:C>T,NM_130837.2:c.2013-639C>T,\N,\N,21/30,Unknown significance,\N,intron_variant,2.126,0.0015,1KG_AFR_AF,OPA1
610249,3:193372027:G>A,NM_130837.2:c.2013-624G>A,\N,\N,21/30,Benign,\N,intron_variant,0.36,0.0875,1KG_EUR_AF,OPA1
610250,3:193372039:C>T,NM_130837.2:c.2013-612C>T,\N,\N,21/30,Unknown significance,\N,intron_variant,2.284,\N,\N,OPA1
610251,3:193372076:G>A,NM_130837.2:c.2013-575G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,9.545,0.0008,1KG_AFR_AF,OPA1
610252,3:193372096:G>A,NM_130837.2:c.2013-555G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,8.601,\N,\N,OPA1
610253,3:193372102:T>C,NM_130837.2:c.2013-549T>C,\N,\N,21/30,Unknown significance,\N,intron_variant,9.194,\N,\N,OPA1
610254,3:193372139:G>A,NM_130837.2:c.2013-512G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,3.497,0.002,1KG_EAS_AF,OPA1
610255,3:193372154:G>A,NM_130837.2:c.2013-497G>A,\N,\N,21/30,Benign,\N,intron_variant,0.088,0.0139,1KG_EUR_AF,OPA1
610256,3:193372214:G>C,NM_130837.2:c.2013-437G>C,\N,\N,21/30,Unknown significance,\N,intron_variant,0.179,\N,\N,OPA1
610257,3:193372248:GT>G,NM_130837.2:c.2013-402del,\N,\N,21/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610258,3:193372258:C>T,NM_130837.2:c.2013-393C>T,\N,\N,21/30,Unknown significance,\N,intron_variant,0.699,0.004,1KG_EUR_AF,OPA1
610259,3:193372265:G>C,NM_130837.2:c.2013-386G>C,\N,\N,21/30,Unknown significance,\N,intron_variant,0.332,0.0008,1KG_AFR_AF,OPA1
610260,3:193372288:C>CA,NM_130837.2:c.2013-350dup,\N,\N,21/30,Benign,\N,intron_variant,3.703,0.2935,1KG_SAS_AF,OPA1
610261,3:193372288:CA>C,NM_130837.2:c.2013-350del,\N,\N,21/30,Unknown significance,\N,intron_variant,4.836,\N,\N,OPA1
610262,3:193372325:G>A,NM_130837.2:c.2013-326G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,3.749,0.0014,1KG_AMR_AF,OPA1
610263,3:193372340:A>G,NM_130837.2:c.2013-311A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,9.672,0.0029,1KG_AMR_AF,OPA1
610264,3:193372344:A>G,NM_130837.2:c.2013-307A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,7.592,0.0014,1KG_AMR_AF,OPA1
610265,3:193372348:A>C,NM_130837.2:c.2013-303A>C,\N,\N,21/30,Unknown significance,\N,intron_variant,8.081,0.001,1KG_SAS_AF,OPA1
610266,3:193372417:GAAAATAC>G,NM_130837.2:c.2013-230_2013-224del,\N,\N,21/30,Unknown significance,\N,intron_variant,10.6,0.0029,1KG_AMR_AF,OPA1
610267,3:193372428:G>A,NM_130837.2:c.2013-223G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,4.096,\N,\N,OPA1
610268,3:193372456:G>A,NM_130837.2:c.2013-195G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,3.354,\N,\N,OPA1
610269,3:193372489:C>G,NM_130837.2:c.2013-162C>G,\N,\N,21/30,Unknown significance,\N,intron_variant,2.139,0.0008,1KG_AFR_AF,OPA1
610270,3:193372507:G>A,NM_130837.2:c.2013-144G>A,\N,\N,21/30,Benign,\N,intron_variant,1.321,0.0367,1KG_EAS_AF,OPA1
610271,3:193372555:G>A,NM_130837.2:c.2013-96G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,3.329,0.001,1KG_EUR_AF,OPA1
610272,3:193372567:A>G,NM_130837.2:c.2013-84A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,2.991,0.0014,1KG_AMR_AF,OPA1
610273,3:193372572:TTAA>T,NM_130837.2:c.2013-77_2013-75del,\N,\N,21/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610274,3:193372577:G>A,NM_130837.2:c.2013-74G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,3.864,\N,\N,OPA1
610275,3:193372584:C>T,NM_130837.2:c.2013-67C>T,\N,\N,21/30,Unknown significance,\N,intron_variant,11.18,\N,\N,OPA1
610276,3:193372590:A>G,NM_130837.2:c.2013-61A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,12.42,\N,\N,OPA1
610277,3:193372603:A>G,NM_130837.2:c.2013-48A>G,\N,\N,21/30,Unknown significance,\N,intron_variant,12.19,\N,\N,OPA1
610278,3:193372605:CA>C,NM_130837.2:c.2013-44del,\N,\N,21/30,Unknown significance,\N,intron_variant,14.87,\N,\N,OPA1
610279,3:193372613:TATTTAG>T,NM_130837.2:c.2013-33_2013-28del,\N,\N,21/30,Unknown significance,\N,intron_variant,15.38,\N,\N,OPA1
610280,3:193372627:G>A,NM_130837.2:c.2013-24G>A,\N,\N,21/30,Unknown significance,\N,intron_variant,12.93,\N,\N,OPA1
610281,3:193372628:CT>C,NM_130837.2:c.2013-19del,\N,\N,21/30,Unknown significance,\N,intron_variant,12.23,0.000019317,EXAC_NFE_AF,OPA1
610282,3:193372634:AT>A,NM_130837.2:c.2013-16del,\N,\N,21/30,Unknown significance,\N,intron_variant,5.363,0.0000688895,EXAC_SAS_AF,OPA1
610283,3:193372637:CTTT>C,NM_130837.2:c.2013-10_2013-8del,\N,\N,21/30,Unknown significance,\N,intron_variant,15.53,\N,\N,OPA1
610284,3:193372644:A>G,NM_130837.2:c.2013-7A>G,\N,\N,21/30,Unknown significance,\N,splice_region_variant&intron_variant,13.2,0.00010636,EXAC_AFR_AF,OPA1
610285,3:193372650:G>A,NM_130837.2:c.2013-1G>A,\N,\N,21/30,Pathogenic,Optic atrophy 1,splice_acceptor_variant,26.4,\N,\N,OPA1
610286,3:193372651:G>A,NM_130837.2:c.2013G>A,NP_570850.2:p.Trp671Ter,22/31,\N,Pathogenic,Optic atrophy 1,stop_gained&splice_region_variant,40,\N,\N,OPA1
610287,3:193372653:A>G,NM_130837.2:c.2015A>G,NP_570850.2:p.Glu672Gly,22/31,\N,Unknown significance,\N,missense_variant&splice_region_variant,32,\N,\N,OPA1
610288,3:193372664:C>T,NM_130837.2:c.2026C>T,NP_570850.2:p.Gln676Ter,22/31,\N,Pathogenic,Optic atrophy 1,stop_gained,44,\N,\N,OPA1
610289,3:193372666:A>G,NM_130837.2:c.2028A>G,NP_570850.2:p.Gln676=,22/31,\N,Unknown significance,\N,synonymous_variant,1.426,0.0000885583,EXAC_AMR_AF,OPA1
610290,3:193372681:AAG>A,NM_130837.2:c.2046_2047del,NP_570850.2:p.Arg682SerfsTer7,22/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,35,\N,\N,OPA1
610291,3:193372682:A>G,NM_130837.2:c.2044A>G,NP_570850.2:p.Arg682Gly,22/31,\N,Unknown significance,\N,missense_variant,16.24,0.0000612295,EXAC_SAS_AF,OPA1
610292,3:193372682:A>T,NM_130837.2:c.2044A>T,NP_570850.2:p.Arg682Ter,22/31,\N,Pathogenic,Optic atrophy 1,stop_gained,42,\N,\N,OPA1
610293,3:193372683:G>A,NM_130837.2:c.2045G>A,NP_570850.2:p.Arg682Lys,22/31,\N,Unknown significance,\N,missense_variant,16.05,0.0000612445,EXAC_SAS_AF,OPA1
610294,3:193372687:A>G,NM_130837.2:c.2049A>G,NP_570850.2:p.Val683=,22/31,\N,Benign,\N,synonymous_variant,8.441,0.0265,1KG_AFR_AF,OPA1
610295,3:193372694:CAT>C,NM_130837.2:c.2057_2058del,NP_570850.2:p.His686ArgfsTer3,22/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,35,\N,\N,OPA1
610296,3:193372700:AT>A,NM_130837.2:c.2064del,NP_570850.2:p.Ile688MetfsTer12,22/31,\N,Pathogenic,Optic atrophy,frameshift_variant,35,\N,\N,OPA1
610297,3:193372702:T>C,NM_130837.2:c.2064T>C,NP_570850.2:p.Ile688=,22/31,\N,Unknown significance,\N,synonymous_variant,7.838,0.000350222,EXAC_EAS_AF,OPA1
610298,3:193372714:C>T,NM_130837.2:c.2076C>T,NP_570850.2:p.Tyr692=,22/31,\N,Unknown significance,\N,synonymous_variant,9.812,0.0000151231,EXAC_NFE_AF,OPA1
610299,3:193372721:G>T,NM_130837.2:c.2083G>T,NP_570850.2:p.Ala695Ser,22/31,\N,Unknown significance,\N,missense_variant,25.2,\N,\N,OPA1
610300,3:193372726:G>A,NM_130837.2:c.2088G>A,NP_570850.2:p.Ala696=,22/31,\N,Benign,\N,synonymous_variant,11.86,0.006,1KG_EAS_AF,OPA1
610301,3:193372730:AC>A,NM_130837.2:c.2094del,NP_570850.2:p.Met699Ter,22/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,35,\N,\N,OPA1
610302,3:193372733:A>G,NM_130837.2:c.2095A>G,NP_570850.2:p.Met699Val,22/31,\N,Unknown significance,\N,missense_variant,12.7,0.0000606943,EXAC_SAS_AF,OPA1
610303,3:193372737:A>G,NM_130837.2:c.2099A>G,NP_570850.2:p.Asn700Ser,22/31,\N,Unknown significance,\N,missense_variant,10.63,0.0008,1KG_AFR_AF,OPA1
610304,3:193372740:C>T,NM_130837.2:c.2102C>T,NP_570850.2:p.Ser701Leu,22/31,\N,Pathogenic,Optic atrophy 1,missense_variant,23.5,\N,\N,OPA1
610305,3:193372746:C>G,NM_130837.2:c.2108C>G,NP_570850.2:p.Thr703Ser,22/31,\N,Unknown significance,\N,missense_variant,19.99,0.0000963391,EXAC_AFR_AF,OPA1
610306,3:193372747:T>C,NM_130837.2:c.2109T>C,NP_570850.2:p.Thr703=,22/31,\N,Unknown significance,\N,synonymous_variant,5.715,0.000116279,EVS_EA_AF,OPA1
610307,3:193372749:T>C,NM_130837.2:c.2111T>C,NP_570850.2:p.Phe704Ser,22/31,\N,Unknown significance,\N,missense_variant,29.5,0.001,1KG_EUR_AF,OPA1
610308,3:193372768:C>G,NM_130837.2:c.2130C>G,NP_570850.2:p.Ile710Met,22/31,\N,Unknown significance,\N,missense_variant,25.6,0.0000606281,EXAC_SAS_AF,OPA1
610309,3:193372771:G>A,NM_130837.2:c.2133G>A,NP_570850.2:p.Lys711=,22/31,\N,Unknown significance,\N,synonymous_variant,12.08,0.000303141,EXAC_SAS_AF,OPA1
610310,3:193372782:G>A,NM_130837.2:c.2144G>A,NP_570850.2:p.Trp715Ter,22/31,\N,Pathogenic,Optic atrophy,stop_gained,42,\N,\N,OPA1
610311,3:193372786:TGA>GG,NM_130837.2:c.2148_2150delinsGG,NP_570850.2:p.Asp717ValfsTer9,22/31,\N,Pathogenic,Optic atrophy,frameshift_variant,\N,\N,\N,OPA1
610312,3:193372792:A>C,NM_015560.2:c.1989A>C,NP_056375.2:p.Lys663Asn,20/29,\N,Likely benign,\N,missense_variant,9.45,0.0000606722,EXAC_SAS_AF,OPA1
610313,3:193372798:T>C,NM_130837.2:c.2160T>C,NP_570850.2:p.Leu720=,22/31,\N,Unknown significance,\N,synonymous_variant,1.51,0.0000150557,EXAC_NFE_AF,OPA1
610314,3:193372800:C>A,NM_130837.2:c.2162C>A,NP_570850.2:p.Pro721His,22/31,\N,Unknown significance,\N,missense_variant,32,\N,\N,OPA1
610315,3:193372802:A>G,NM_130837.2:c.2164A>G,NP_570850.2:p.Asn722Asp,22/31,\N,Unknown significance,\N,missense_variant,16.84,0.0000150648,EXAC_NFE_AF,OPA1
610316,3:193372803:A>G,NM_130837.2:c.2165A>G,NP_570850.2:p.Asn722Ser,22/31,\N,Unknown significance,\N,missense_variant,10.43,0.0000150707,EXAC_NFE_AF,OPA1
610317,3:193372816:G>A,NM_130837.2:c.2178G>A,NP_570850.2:p.Glu726=,22/31,\N,Likely pathogenic,Optic atrophy 1,splice_region_variant&synonymous_variant,14.53,\N,\N,OPA1
610318,3:193372817:G>A,NM_130837.2:c.2178+1G>A,\N,\N,22/30,Pathogenic,Optic atrophy 1,splice_donor_variant,27.3,\N,\N,OPA1
610319,3:193372817:G>C,NM_130837.2:c.2178+1G>C,\N,\N,22/30,Pathogenic,Optic atrophy,splice_donor_variant,25.9,\N,\N,OPA1
610320,3:193372817:G>T,NM_130837.2:c.2178+1G>T,\N,\N,22/30,Pathogenic,Optic atrophy 1,splice_donor_variant,26.2,\N,\N,OPA1
610321,3:193372825:A>G,NM_130837.2:c.2178+9A>G,\N,\N,22/30,Unknown significance,\N,intron_variant,16.74,0.0000873973,EXAC_AMR_AF,OPA1
610322,3:193372837:A>G,NM_130837.2:c.2178+21A>G,\N,\N,22/30,Unknown significance,\N,intron_variant,17.62,0.000175562,EXAC_AMR_AF,OPA1
610323,3:193372855:T>C,NM_130837.2:c.2178+39T>C,\N,\N,22/30,Unknown significance,\N,intron_variant,14.83,0.0000881368,EXAC_AMR_AF,OPA1
610324,3:193372858:G>A,NM_130837.2:c.2178+42G>A,\N,\N,22/30,Unknown significance,\N,intron_variant,15.41,0.000102902,EXAC_AFR_AF,OPA1
610325,3:193372861:G>C,NM_130837.2:c.2178+45G>C,\N,\N,22/30,Unknown significance,\N,intron_variant,13.33,\N,\N,OPA1
610326,3:193372866:T>C,NM_130837.2:c.2178+50T>C,\N,\N,22/30,Unknown significance,\N,intron_variant,13.84,0.0000620732,EXAC_SAS_AF,OPA1
610327,3:193372868:G>A,NM_130837.2:c.2178+52G>A,\N,\N,22/30,Unknown significance,\N,intron_variant,18.16,0.0000900252,EXAC_AMR_AF,OPA1
610328,3:193372886:T>A,NM_130837.2:c.2178+70T>A,\N,\N,22/30,Unknown significance,\N,intron_variant,10.93,\N,\N,OPA1
610329,3:193372897:T>C,NM_130837.2:c.2178+81T>C,\N,\N,22/30,Unknown significance,\N,intron_variant,13.8,\N,\N,OPA1
610330,3:193372904:C>A,NM_130837.2:c.2178+88C>A,\N,\N,22/30,Unknown significance,\N,intron_variant,11.2,0.003,1KG_EUR_AF,OPA1
610331,3:193372908:A>T,NM_130837.2:c.2178+92A>T,\N,\N,22/30,Benign,\N,intron_variant,2.38,0.0378,1KG_SAS_AF,OPA1
610332,3:193372920:G>C,NM_130837.2:c.2178+104G>C,\N,\N,22/30,Unknown significance,\N,intron_variant,3.724,0.0008,1KG_AFR_AF,OPA1
610333,3:193372965:G>C,NM_130837.2:c.2178+149G>C,\N,\N,22/30,Unknown significance,\N,intron_variant,4.025,\N,\N,OPA1
610334,3:193372970:A>G,NM_130837.2:c.2178+154A>G,\N,\N,22/30,Unknown significance,\N,intron_variant,10.99,0.001,1KG_SAS_AF,OPA1
610335,3:193372995:C>T,NM_130837.2:c.2178+179C>T,\N,\N,22/30,Unknown significance,\N,intron_variant,1.554,0.0029,1KG_AMR_AF,OPA1
610336,3:193373039:A>G,NM_130837.2:c.2178+223A>G,\N,\N,22/30,Benign,\N,intron_variant,9.311,0.005,1KG_EAS_AF,OPA1
610337,3:193373046:C>T,NM_130837.2:c.2178+230C>T,\N,\N,22/30,Unknown significance,\N,intron_variant,9.336,0.001,1KG_SAS_AF,OPA1
610338,3:193373058:A>G,NM_130837.2:c.2178+242A>G,\N,\N,22/30,Unknown significance,\N,intron_variant,4.769,\N,\N,OPA1
610339,3:193373069:C>G,NM_130837.2:c.2178+253C>G,\N,\N,22/30,Benign,\N,intron_variant,5.292,0.0865,1KG_EUR_AF,OPA1
610340,3:193373094:ATATTTGCTTGAG>A,NM_130837.2:c.2178+290_2178+301del,\N,\N,22/30,Unknown significance,\N,intron_variant,4.924,0.003,1KG_EUR_AF,OPA1
610341,3:193373103:T>C,NM_130837.2:c.2178+287T>C,\N,\N,22/30,Unknown significance,\N,intron_variant,1.234,0.0014,1KG_AMR_AF,OPA1
610342,3:193373155:G>T,NM_130837.2:c.2178+339G>T,\N,\N,22/30,Unknown significance,\N,intron_variant,0.479,0.001,1KG_EUR_AF,OPA1
610343,3:193373172:A>G,NM_130837.2:c.2178+356A>G,\N,\N,22/30,Unknown significance,\N,intron_variant,1.466,0.001,1KG_SAS_AF,OPA1
610344,3:193373197:A>G,NM_130837.2:c.2178+381A>G,\N,\N,22/30,Unknown significance,\N,intron_variant,4.023,0.0008,1KG_AFR_AF,OPA1
610345,3:193373229:C>T,NM_130837.2:c.2178+413C>T,\N,\N,22/30,Benign,\N,intron_variant,5.105,0.1248,1KG_AFR_AF,OPA1
610346,3:193373273:AAAAAC>A,NM_130837.2:c.2178+477_2178+481del,\N,\N,22/30,Unknown significance,\N,intron_variant,0.976,0.0014,1KG_AMR_AF,OPA1
610347,3:193373310:G>T,NM_130837.2:c.2178+494G>T,\N,\N,22/30,Unknown significance,\N,intron_variant,8.245,0.001,1KG_EAS_AF,OPA1
610348,3:193373389:T>A,NM_130837.2:c.2178+573T>A,\N,\N,22/30,Unknown significance,\N,intron_variant,5.059,\N,\N,OPA1
610349,3:193373394:G>GT,NM_130837.2:c.2178+584dup,\N,\N,22/30,Benign,\N,intron_variant,4.149,0.0268,1KG_EUR_AF,OPA1
610350,3:193373420:A>G,NM_130837.2:c.2178+604A>G,\N,\N,22/30,Unknown significance,\N,intron_variant,2.22,\N,\N,OPA1
610351,3:193373421:T>A,NM_130837.2:c.2178+605T>A,\N,\N,22/30,Unknown significance,\N,intron_variant,7.175,0.0015,1KG_AFR_AF,OPA1
610352,3:193373471:A>C,NM_130837.2:c.2178+655A>C,\N,\N,22/30,Unknown significance,\N,intron_variant,0.42,\N,\N,OPA1
610353,3:193373473:G>A,NM_130837.2:c.2178+657G>A,\N,\N,22/30,Unknown significance,\N,intron_variant,3.307,\N,\N,OPA1
610354,3:193373490:T>C,NM_130837.2:c.2178+674T>C,\N,\N,22/30,Benign,\N,intron_variant,6.127,0.0367,1KG_EAS_AF,OPA1
610355,3:193373513:A>AG,NM_130837.2:c.2178+700dup,\N,\N,22/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610356,3:193373515:G>A,NM_130837.2:c.2178+699G>A,\N,\N,22/30,Unknown significance,\N,intron_variant,5.368,\N,\N,OPA1
610357,3:193373516:G>GA,NM_130837.2:c.2178+702dup,\N,\N,22/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610358,3:193373543:C>T,NM_130837.2:c.2178+727C>T,\N,\N,22/30,Benign,\N,intron_variant,3.929,0.1248,1KG_AFR_AF,OPA1
610359,3:193373586:C>T,NM_130837.2:c.2178+770C>T,\N,\N,22/30,Unknown significance,\N,intron_variant,7.54,\N,\N,OPA1
610360,3:193373592:T>G,NM_130837.2:c.2178+776T>G,\N,\N,22/30,Unknown significance,\N,intron_variant,2.727,\N,\N,OPA1
610361,3:193373632:G>A,NM_130837.2:c.2178+816G>A,\N,\N,22/30,Unknown significance,\N,intron_variant,4.926,\N,\N,OPA1
610362,3:193373647:G>A,NM_130837.2:c.2178+831G>A,\N,\N,22/30,Unknown significance,\N,intron_variant,3.624,\N,\N,OPA1
610363,3:193373736:C>G,NM_130837.2:c.2178+920C>G,\N,\N,22/30,Benign,\N,intron_variant,3.982,0.0133,1KG_SAS_AF,OPA1
610364,3:193373737:C>T,NM_130837.2:c.2178+921C>T,\N,\N,22/30,Unknown significance,\N,intron_variant,7.553,0.0008,1KG_AFR_AF,OPA1
610365,3:193373751:T>C,NM_130837.2:c.2178+935T>C,\N,\N,22/30,Unknown significance,\N,intron_variant,2.613,0.001,1KG_SAS_AF,OPA1
610366,3:193373768:C>G,NM_130837.2:c.2178+952C>G,\N,\N,22/30,Unknown significance,\N,intron_variant,5.085,0.001,1KG_SAS_AF,OPA1
610367,3:193373776:A>G,NM_130837.2:c.2178+960A>G,\N,\N,22/30,Unknown significance,\N,intron_variant,3.301,0.002,1KG_SAS_AF,OPA1
610368,3:193373793:T>G,NM_130837.2:c.2178+977T>G,\N,\N,22/30,Unknown significance,\N,intron_variant,5.349,0.001,1KG_EAS_AF,OPA1
610369,3:193373804:C>G,NM_130837.2:c.2178+988C>G,\N,\N,22/30,Unknown significance,\N,intron_variant,3.336,0.0029,1KG_AMR_AF,OPA1
610370,3:193373810:G>C,NM_130837.2:c.2178+994G>C,\N,\N,22/30,Benign,\N,intron_variant,2.814,0.1248,1KG_AFR_AF,OPA1
610371,3:193373816:C>G,NM_130837.2:c.2178+1000C>G,\N,\N,22/30,Benign,\N,intron_variant,3.74,0.0238,1KG_EAS_AF,OPA1
610372,3:193373889:G>A,NM_130837.2:c.2179-980G>A,\N,\N,22/30,Unknown significance,\N,intron_variant,4.437,0.0014,1KG_AMR_AF,OPA1
610373,3:193373903:A>G,NM_130837.2:c.2179-966A>G,\N,\N,22/30,Unknown significance,\N,intron_variant,5.178,\N,\N,OPA1
610374,3:193373921:T>A,NM_130837.2:c.2179-948T>A,\N,\N,22/30,Unknown significance,\N,intron_variant,7.391,\N,\N,OPA1
610375,3:193373925:A>G,NM_130837.2:c.2179-944A>G,\N,\N,22/30,Unknown significance,\N,intron_variant,3.083,\N,\N,OPA1
610376,3:193373936:G>A,NM_130837.2:c.2179-933G>A,\N,\N,22/30,Benign,\N,intron_variant,5.135,0.0875,1KG_EUR_AF,OPA1
610377,3:193373953:G>T,NM_130837.2:c.2179-916G>T,\N,\N,22/30,Unknown significance,\N,intron_variant,6.353,0.0029,1KG_AMR_AF,OPA1
610378,3:193373966:C>A,NM_130837.2:c.2179-903C>A,\N,\N,22/30,Unknown significance,\N,intron_variant,11.68,\N,\N,OPA1
610379,3:193373989:G>A,NM_130837.2:c.2179-880G>A,\N,\N,22/30,Unknown significance,\N,intron_variant,3.856,\N,\N,OPA1
610380,3:193374034:C>G,NM_130837.2:c.2179-835C>G,\N,\N,22/30,Unknown significance,\N,intron_variant,3.723,\N,\N,OPA1
610381,3:193374088:A>C,NM_130837.2:c.2179-781A>C,\N,\N,22/30,Unknown significance,\N,intron_variant,0.077,0.001,1KG_SAS_AF,OPA1
610382,3:193374102:T>C,NM_130837.2:c.2179-767T>C,\N,\N,22/30,Unknown significance,\N,intron_variant,1.323,0.002,1KG_SAS_AF,OPA1
610383,3:193374124:T>G,NM_130837.2:c.2179-745T>G,\N,\N,22/30,Unknown significance,\N,intron_variant,1.124,\N,\N,OPA1
610384,3:193374131:A>G,NM_130837.2:c.2179-738A>G,\N,\N,22/30,Unknown significance,\N,intron_variant,1.694,\N,\N,OPA1
610385,3:193374132:C>T,NM_130837.2:c.2179-737C>T,\N,\N,22/30,Unknown significance,\N,intron_variant,7.112,0.0008,1KG_AFR_AF,OPA1
610386,3:193374143:T>A,NM_130837.2:c.2179-726T>A,\N,\N,22/30,Unknown significance,\N,intron_variant,1.853,\N,\N,OPA1
610387,3:193374244:A>C,NM_130837.2:c.2179-625A>C,\N,\N,22/30,Unknown significance,\N,intron_variant,0.484,\N,\N,OPA1
610388,3:193374248:T>G,NM_130837.2:c.2179-621T>G,\N,\N,22/30,Unknown significance,\N,intron_variant,2.984,0.001,1KG_SAS_AF,OPA1
610389,3:193374255:C>T,NM_130837.2:c.2179-614C>T,\N,\N,22/30,Unknown significance,\N,intron_variant,5.172,\N,\N,OPA1
610390,3:193374270:A>G,NM_130837.2:c.2179-599A>G,\N,\N,22/30,Unknown significance,\N,intron_variant,3.369,0.001,1KG_EUR_AF|1KG_SAS_AF,OPA1
610391,3:193374367:A>C,NM_130837.2:c.2179-502A>C,\N,\N,22/30,Unknown significance,\N,intron_variant,4.573,0.0014,1KG_AMR_AF,OPA1
610392,3:193374384:C>T,NM_130837.2:c.2179-485C>T,\N,\N,22/30,Benign,\N,intron_variant,6.641,0.5855,1KG_AFR_AF,OPA1
610393,3:193374389:G>A,NM_130837.2:c.2179-480G>A,\N,\N,22/30,Unknown significance,\N,intron_variant,1.77,0.002,1KG_EAS_AF,OPA1
610394,3:193374390:C>A,NM_130837.2:c.2179-479C>A,\N,\N,22/30,Unknown significance,\N,intron_variant,3.771,\N,\N,OPA1
610395,3:193374424:A>AG,NM_130837.2:c.2179-443dup,\N,\N,22/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610396,3:193374446:T>C,NM_130837.2:c.2179-423T>C,\N,\N,22/30,Unknown significance,\N,intron_variant,5.702,\N,\N,OPA1
610397,3:193374450:T>C,NM_130837.2:c.2179-419T>C,\N,\N,22/30,Unknown significance,\N,intron_variant,3.314,\N,\N,OPA1
610398,3:193374547:CAGTT>C,NM_130837.2:c.2179-318_2179-315del,\N,\N,22/30,Unknown significance,\N,intron_variant,7.906,0.0031,1KG_SAS_AF,OPA1
610399,3:193374566:C>T,NM_130837.2:c.2179-303C>T,\N,\N,22/30,Benign,\N,intron_variant,6.747,0.0367,1KG_EAS_AF,OPA1
610400,3:193374590:A>G,NM_130837.2:c.2179-279A>G,\N,\N,22/30,Unknown significance,\N,intron_variant,1.333,\N,\N,OPA1
610401,3:193374612:G>A,NM_130837.2:c.2179-257G>A,\N,\N,22/30,Unknown significance,\N,intron_variant,4.497,\N,\N,OPA1
610402,3:193374636:C>T,NM_130837.2:c.2179-233C>T,\N,\N,22/30,Unknown significance,\N,intron_variant,7.384,\N,\N,OPA1
610403,3:193374647:T>C,NM_130837.2:c.2179-222T>C,\N,\N,22/30,Unknown significance,\N,intron_variant,3.494,\N,\N,OPA1
610404,3:193374687:A>AC,NM_130837.2:c.2179-179dup,\N,\N,22/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610405,3:193374690:C>T,NM_130837.2:c.2179-179C>T,\N,\N,22/30,Unknown significance,\N,intron_variant,5.198,\N,\N,OPA1
610406,3:193374691:G>A,NM_130837.2:c.2179-178G>A,\N,\N,22/30,Unknown significance,\N,intron_variant,1.935,0.0041,1KG_SAS_AF,OPA1
610407,3:193374700:C>T,NM_130837.2:c.2179-169C>T,\N,\N,22/30,Unknown significance,\N,intron_variant,9.146,\N,\N,OPA1
610408,3:193374763:CT>C,NM_130837.2:c.2179-105del,\N,\N,22/30,Benign,\N,intron_variant,16.77,0.0151,1KG_AFR_AF,OPA1
610409,3:193374788:G>T,NM_130837.2:c.2179-81G>T,\N,\N,22/30,Benign,\N,intron_variant,0.813,0.1369,1KG_AFR_AF,OPA1
610410,3:193374793:A>G,NM_130837.2:c.2179-76A>G,\N,\N,22/30,Unknown significance,\N,intron_variant,4.097,0.0008,1KG_AFR_AF,OPA1
610411,3:193374798:G>A,NM_130837.2:c.2179-71G>A,\N,\N,22/30,Unknown significance,\N,intron_variant,6.882,\N,\N,OPA1
610412,3:193374801:T>C,NM_130837.2:c.2179-68T>C,\N,\N,22/30,Unknown significance,\N,intron_variant,8.395,\N,\N,OPA1
610413,3:193374820:T>G,NM_130837.2:c.2179-49T>G,\N,\N,22/30,Unknown significance,\N,intron_variant,3.947,0.0000656685,EXAC_SAS_AF,OPA1
610414,3:193374830:T>C,NM_130837.2:c.2179-39T>C,\N,\N,22/30,Unknown significance,\N,intron_variant,3.363,0.0008,1KG_AFR_AF,OPA1
610415,3:193374832:G>A,NM_130837.2:c.2179-37G>A,\N,\N,22/30,Unknown significance,\N,intron_variant,3.398,0.0014,1KG_AMR_AF,OPA1
610416,3:193374842:G>GGC,NM_130837.2:c.2179-26_2179-25dup,\N,\N,22/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610417,3:193374843:G>A,NM_130837.2:c.2179-26G>A,\N,\N,22/30,Unknown significance,\N,intron_variant,1.837,0.000234192,EXAC_EAS_AF,OPA1
610418,3:193374844:C>CT,NM_130837.2:c.2179-18dup,\N,\N,22/30,Unknown significance,\N,intron_variant,8.693,0.0000869112,EXAC_AMR_AF,OPA1
610419,3:193374845:T>G,NM_130837.2:c.2179-24T>G,\N,\N,22/30,Benign,\N,intron_variant,5.482,0.0230083,EXAC_SAS_AF,OPA1
610420,3:193374846:T>C,NM_130837.2:c.2179-23T>C,\N,\N,22/30,Benign,\N,intron_variant,3.418,0.0230221,EXAC_SAS_AF,OPA1
610421,3:193374848:T>C,NM_130837.2:c.2179-21T>C,\N,\N,22/30,Unknown significance,\N,intron_variant,4.716,0.0014,1KG_AMR_AF,OPA1
610422,3:193374856:CA>C,NM_130837.2:c.2179-10del,\N,\N,22/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610423,3:193374867:A>G,NM_130837.2:c.2179-2A>G,\N,\N,22/30,Unknown significance,\N,splice_acceptor_variant,25,0.000015098,EXAC_NFE_AF,OPA1
610424,3:193374868:G>A,NM_130837.2:c.2179-1G>A,\N,\N,22/30,Likely pathogenic,Optic atrophy 1,splice_acceptor_variant,26.8,\N,\N,OPA1
610425,3:193374881:AC>A,NM_130837.2:c.2194del,NP_570850.2:p.Leu732TyrfsTer9,23/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,36,\N,\N,OPA1
610426,3:193374883:C>G,NM_130837.2:c.2193C>G,NP_570850.2:p.Thr731=,23/31,\N,Unknown significance,\N,synonymous_variant,14.4,0.0000606796,EXAC_SAS_AF,OPA1
610427,3:193374889:A>G,NM_130837.2:c.2199A>G,NP_570850.2:p.Gln733=,23/31,\N,Unknown significance,\N,synonymous_variant,7.551,0.0000150281,EXAC_NFE_AF,OPA1
610428,3:193374891:A>T,NM_130837.2:c.2201A>T,NP_570850.2:p.Glu734Val,23/31,\N,Unknown significance,\N,missense_variant,24.1,0.000116279,EVS_EA_AF,OPA1
610429,3:193374903:G>A,NM_015560.2:c.2048G>A,NP_056375.2:p.Arg683His,21/29,\N,Unknown significance,\N,missense_variant,24,0.0000300327,EXAC_NFE_AF,OPA1
610430,3:193374912:CAG>C,NM_130837.2:c.2224_2225del,NP_570850.2:p.Glu742ThrfsTer7,23/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,36,\N,\N,OPA1
610431,3:193374914:GA>G,NM_130837.2:c.2226del,NP_570850.2:p.Glu742AspfsTer36,23/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,35,\N,\N,OPA1
610432,3:193374915:A>G,NM_130837.2:c.2225A>G,NP_570850.2:p.Glu742Gly,23/31,\N,Unknown significance,\N,missense_variant,23.2,0.0000972006,EXAC_AFR_AF,OPA1
610433,3:193374917:C>G,NM_130837.2:c.2227C>G,NP_570850.2:p.Pro743Ala,23/31,\N,Unknown significance,\N,missense_variant,12.24,0.0000864304,EXAC_AMR_AF,OPA1
610434,3:193374918:C>T,NM_130837.2:c.2228C>T,NP_570850.2:p.Pro743Leu,23/31,\N,Unknown significance,\N,missense_variant,23.5,0.0000300075,EXAC_NFE_AF,OPA1
610435,3:193374919:G>A,NM_130837.2:c.2229G>A,NP_570850.2:p.Pro743=,23/31,\N,Unknown significance,\N,synonymous_variant,13.52,0.000060562,EXAC_SAS_AF,OPA1
610436,3:193374925:G>A,NM_130837.2:c.2235G>A,NP_570850.2:p.Gly745=,23/31,\N,Unknown significance,\N,synonymous_variant,12.16,0.0000150006,EXAC_NFE_AF,OPA1
610437,3:193374931:G>A,NM_130837.2:c.2241G>A,NP_570850.2:p.Glu747=,23/31,\N,Unknown significance,\N,synonymous_variant,11.36,0.000060562,EXAC_SAS_AF,OPA1
610438,3:193374940:C>T,NM_130837.2:c.2250C>T,NP_570850.2:p.Asp750=,23/31,\N,Unknown significance,\N,synonymous_variant,13.88,0.000060562,EXAC_SAS_AF,OPA1
610439,3:193374948:ATAAACT>A,NM_130837.2:c.2263_2268del,NP_570850.2:p.Leu755_Lys756del,23/31,\N,Pathogenic,Optic atrophy 1,inframe_deletion,23.4,\N,\N,OPA1
610440,3:193374953:C>T,NM_130837.2:c.2263C>T,NP_570850.2:p.Leu755Phe,23/31,\N,Unknown significance,\N,missense_variant,33,0.0000149957,EXAC_NFE_AF,OPA1
610441,3:193374955:TAA>T,NM_130837.2:c.2267_2268del,NP_570850.2:p.Lys756ArgfsTer4,23/31,\N,Pathogenic,Optic atrophy,frameshift_variant,35,\N,\N,OPA1
610442,3:193374964:T>C,NM_130837.2:c.2274T>C,NP_570850.2:p.Ala758=,23/31,\N,Benign,\N,synonymous_variant,9.373,0.5862,1KG_AFR_AF,OPA1
610443,3:193374974:G>T,NM_130837.2:c.2284G>T,NP_570850.2:p.Glu762Ter,23/31,\N,Pathogenic,Optic atrophy,stop_gained,49,\N,\N,OPA1
610444,3:193374974:GA>G,NM_130837.2:c.2287del,NP_570850.2:p.Ser763ValfsTer15,23/31,\N,Pathogenic,Optic neuropathy,frameshift_variant,35,\N,\N,OPA1
610445,3:193374977:A>G,NM_130837.2:c.2287A>G,NP_570850.2:p.Ser763Gly,23/31,\N,Unknown significance,\N,missense_variant,23.5,\N,\N,OPA1
610446,3:193374980:ATTAAACGACACAA>GGATCGACACAC,NM_130837.2:c.2290_2303delinsGGATCGACACAC,NP_570850.2:p.Ile764GlyfsTer7,23/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,\N,\N,\N,OPA1
610447,3:193374983:A>G,NM_130837.2:c.2293A>G,NP_570850.2:p.Lys765Glu,23/31,\N,Unknown significance,\N,missense_variant,22.7,0.000259202,EXAC_AMR_AF,OPA1
610448,3:193374986:C>T,NM_130837.2:c.2296C>T,NP_570850.2:p.Arg766Ter,23/31,\N,Pathogenic,Optic atrophy 1,stop_gained,45,\N,\N,OPA1
610449,3:193374996:G>A,NM_130837.2:c.2306G>A,NP_570850.2:p.Trp769Ter,23/31,\N,Pathogenic,Optic atrophy,stop_gained,44,\N,\N,OPA1
610450,3:193375008:C>A,NM_130837.2:c.2318C>A,NP_570850.2:p.Ala773Glu,23/31,\N,Pathogenic,Optic atrophy,missense_variant,35,\N,\N,OPA1
610451,3:193375009:G>A,NM_130837.2:c.2319G>A,NP_570850.2:p.Ala773=,23/31,\N,Unknown significance,\N,synonymous_variant,15.44,0.000226963,EVS_AA_AF,OPA1
610452,3:193375011:A>G,NM_130837.2:c.2321A>G,NP_570850.2:p.Glu774Gly,23/31,\N,Unknown significance,\N,missense_variant,23,0.001,1KG_EAS_AF,OPA1
610453,3:193375031:T>C,NM_130837.2:c.2331+10T>C,\N,\N,23/30,Unknown significance,\N,intron_variant,2.403,0.001,1KG_EUR_AF,OPA1
610454,3:193375040:G>A,NM_130837.2:c.2331+19G>A,\N,\N,23/30,Unknown significance,\N,intron_variant,4.508,0.0000150485,EXAC_NFE_AF,OPA1
610455,3:193375041:G>A,NM_130837.2:c.2331+20G>A,\N,\N,23/30,Unknown significance,\N,intron_variant,5.439,0.000115848,EXAC_EAS_AF,OPA1
610456,3:193375041:G>C,NM_130837.2:c.2331+20G>C,\N,\N,23/30,Unknown significance,\N,intron_variant,2.134,0.000116279,EVS_EA_AF,OPA1
610457,3:193375048:A>G,NM_130837.2:c.2331+27A>G,\N,\N,23/30,Unknown significance,\N,intron_variant,10.34,0.0000150734,EXAC_NFE_AF,OPA1
610458,3:193375053:CAT>C,NM_130837.2:c.2331+35_2331+36del,\N,\N,23/30,Unknown significance,\N,intron_variant,13.89,0.000485084,EXAC_SAS_AF,OPA1
610459,3:193375056:AT>A,NM_130837.2:c.2331+40del,\N,\N,23/30,Unknown significance,\N,intron_variant,13.12,0.000151423,EXAC_FIN_AF,OPA1
610460,3:193375074:A>T,NM_130837.2:c.2331+53A>T,\N,\N,23/30,Unknown significance,\N,intron_variant,4.841,0.001,1KG_EAS_AF,OPA1
610461,3:193375098:C>A,NM_130837.2:c.2331+77C>A,\N,\N,23/30,Unknown significance,\N,intron_variant,6.533,0.001,1KG_EUR_AF,OPA1
610462,3:193375120:C>A,NM_130837.2:c.2331+99C>A,\N,\N,23/30,Unknown significance,\N,intron_variant,9.98,0.0014,1KG_AMR_AF,OPA1
610463,3:193375120:C>T,NM_130837.2:c.2331+99C>T,\N,\N,23/30,Unknown significance,\N,intron_variant,10.07,\N,\N,OPA1
610464,3:193375136:G>T,NM_130837.2:c.2331+115G>T,\N,\N,23/30,Benign,\N,intron_variant,1.686,0.0231,1KG_AMR_AF,OPA1
610465,3:193375138:A>T,NM_130837.2:c.2331+117A>T,\N,\N,23/30,Unknown significance,\N,intron_variant,4.048,0.001,1KG_EAS_AF,OPA1
610466,3:193375185:C>G,NM_130837.2:c.2331+164C>G,\N,\N,23/30,Unknown significance,\N,intron_variant,3.996,0.0015,1KG_AFR_AF,OPA1
610467,3:193375196:A>G,NM_130837.2:c.2331+175A>G,\N,\N,23/30,Unknown significance,\N,intron_variant,2.179,0.002,1KG_EAS_AF,OPA1
610468,3:193375223:G>A,NM_130837.2:c.2331+202G>A,\N,\N,23/30,Unknown significance,\N,intron_variant,8.011,0.0008,1KG_AFR_AF,OPA1
610469,3:193375226:A>G,NM_130837.2:c.2331+205A>G,\N,\N,23/30,Unknown significance,\N,intron_variant,1.545,0.001,1KG_EAS_AF,OPA1
610470,3:193375252:G>T,NM_130837.2:c.2331+231G>T,\N,\N,23/30,Unknown significance,\N,intron_variant,1.482,\N,\N,OPA1
610471,3:193375313:G>A,NM_130837.2:c.2331+292G>A,\N,\N,23/30,Unknown significance,\N,intron_variant,2.669,\N,\N,OPA1
610472,3:193375337:T>C,NM_130837.2:c.2331+316T>C,\N,\N,23/30,Unknown significance,\N,intron_variant,10.74,0.001,1KG_EAS_AF,OPA1
610473,3:193375368:G>C,NM_130837.2:c.2331+347G>C,\N,\N,23/30,Unknown significance,\N,intron_variant,0.147,\N,\N,OPA1
610474,3:193375401:C>T,NM_130837.2:c.2331+380C>T,\N,\N,23/30,Unknown significance,\N,intron_variant,4.4,\N,\N,OPA1
610475,3:193375402:G>T,NM_130837.2:c.2331+381G>T,\N,\N,23/30,Unknown significance,\N,intron_variant,1.493,\N,\N,OPA1
610476,3:193375445:A>G,NM_130837.2:c.2331+424A>G,\N,\N,23/30,Unknown significance,\N,intron_variant,4.687,0.0008,1KG_AFR_AF,OPA1
610477,3:193375483:T>G,NM_130837.2:c.2331+462T>G,\N,\N,23/30,Unknown significance,\N,intron_variant,2.72,\N,\N,OPA1
610478,3:193375500:C>T,NM_130837.2:c.2331+479C>T,\N,\N,23/30,Unknown significance,\N,intron_variant,1.729,0.0045,1KG_AFR_AF,OPA1
610479,3:193375514:G>A,NM_130837.2:c.2331+493G>A,\N,\N,23/30,Unknown significance,\N,intron_variant,7.205,\N,\N,OPA1
610480,3:193375522:C>T,NM_130837.2:c.2331+501C>T,\N,\N,23/30,Unknown significance,\N,intron_variant,10.31,0.0041,1KG_SAS_AF,OPA1
610481,3:193375565:C>T,NM_130837.2:c.2331+544C>T,\N,\N,23/30,Unknown significance,\N,intron_variant,5.861,\N,\N,OPA1
610482,3:193375599:A>T,NM_130837.2:c.2331+578A>T,\N,\N,23/30,Unknown significance,\N,intron_variant,2.444,0.0008,1KG_AFR_AF,OPA1
610483,3:193375624:C>T,NM_130837.2:c.2331+603C>T,\N,\N,23/30,Unknown significance,\N,intron_variant,6.729,\N,\N,OPA1
610484,3:193375659:A>C,NM_130837.2:c.2331+638A>C,\N,\N,23/30,Unknown significance,\N,intron_variant,0.54,0.0008,1KG_AFR_AF,OPA1
610485,3:193375686:G>A,NM_130837.2:c.2331+665G>A,\N,\N,23/30,Unknown significance,\N,intron_variant,2.207,0.0043,1KG_AMR_AF,OPA1
610486,3:193375702:G>A,NM_130837.2:c.2331+681G>A,\N,\N,23/30,Unknown significance,\N,intron_variant,1.533,0.0014,1KG_AMR_AF,OPA1
610487,3:193375707:G>A,NM_130837.2:c.2331+686G>A,\N,\N,23/30,Unknown significance,\N,intron_variant,1.5,\N,\N,OPA1
610488,3:193375753:G>A,NM_130837.2:c.2331+732G>A,\N,\N,23/30,Unknown significance,\N,intron_variant,5.224,\N,\N,OPA1
610489,3:193375757:G>A,NM_130837.2:c.2331+736G>A,\N,\N,23/30,Unknown significance,\N,intron_variant,3.635,\N,\N,OPA1
610490,3:193375760:C>T,NM_130837.2:c.2331+739C>T,\N,\N,23/30,Unknown significance,\N,intron_variant,5.365,\N,\N,OPA1
610491,3:193375797:G>A,NM_130837.2:c.2331+776G>A,\N,\N,23/30,Unknown significance,\N,intron_variant,3.641,0.0031,1KG_SAS_AF,OPA1
610492,3:193375800:C>T,NM_130837.2:c.2331+779C>T,\N,\N,23/30,Unknown significance,\N,intron_variant,6.762,0.001,1KG_EUR_AF,OPA1
610493,3:193375801:G>A,NM_130837.2:c.2331+780G>A,\N,\N,23/30,Unknown significance,\N,intron_variant,0.924,0.0029,1KG_AMR_AF,OPA1
610494,3:193375847:C>T,NM_130837.2:c.2331+826C>T,\N,\N,23/30,Benign,\N,intron_variant,1.727,0.0053,1KG_AFR_AF,OPA1
610495,3:193375861:C>T,NM_130837.2:c.2332-815C>T,\N,\N,23/30,Unknown significance,\N,intron_variant,2.499,0.002,1KG_EAS_AF,OPA1
610496,3:193375863:C>T,NM_130837.2:c.2332-813C>T,\N,\N,23/30,Unknown significance,\N,intron_variant,0.439,\N,\N,OPA1
610497,3:193375864:G>A,NM_130837.2:c.2332-812G>A,\N,\N,23/30,Unknown significance,\N,intron_variant,1.496,\N,\N,OPA1
610498,3:193375910:T>A,NM_130837.2:c.2332-766T>A,\N,\N,23/30,Unknown significance,\N,intron_variant,5.867,0.0008,1KG_AFR_AF,OPA1
610499,3:193375927:G>T,NM_130837.2:c.2332-749G>T,\N,\N,23/30,Unknown significance,\N,intron_variant,0.726,0.0008,1KG_AFR_AF,OPA1
610500,3:193375956:C>T,NM_130837.2:c.2332-720C>T,\N,\N,23/30,Benign,\N,intron_variant,2.854,0.0053,1KG_AFR_AF,OPA1
610501,3:193375974:C>T,NM_130837.2:c.2332-702C>T,\N,\N,23/30,Unknown significance,\N,intron_variant,2.116,0.0008,1KG_AFR_AF,OPA1
610502,3:193375975:G>A,NM_130837.2:c.2332-701G>A,\N,\N,23/30,Unknown significance,\N,intron_variant,0.297,\N,\N,OPA1
610503,3:193375975:G>C,NM_130837.2:c.2332-701G>C,\N,\N,23/30,Unknown significance,\N,intron_variant,0.042,\N,\N,OPA1
610504,3:193375975:G>T,NM_130837.2:c.2332-701G>T,\N,\N,23/30,Benign,\N,intron_variant,0.085,0.0164,1KG_SAS_AF,OPA1
610505,3:193376029:C>G,NM_130837.2:c.2332-647C>G,\N,\N,23/30,Benign,\N,intron_variant,0.427,0.0367,1KG_EAS_AF,OPA1
610506,3:193376034:TCAAAAAAAA>T,NM_130837.2:c.2332-641_2332-633del,\N,\N,23/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610507,3:193376035:C>A,NM_130837.2:c.2332-641C>A,\N,\N,23/30,Unknown significance,\N,intron_variant,2.225,\N,\N,OPA1
610508,3:193376035:CAA>C,NM_130837.2:c.2332-624_2332-623del,\N,\N,23/30,Unknown significance,\N,intron_variant,5.097,\N,\N,OPA1
610509,3:193376035:CAAA>C,NM_130837.2:c.2332-625_2332-623del,\N,\N,23/30,Unknown significance,\N,intron_variant,5.928,\N,\N,OPA1
610510,3:193376035:CAAAAAA>C,NM_130837.2:c.2332-628_2332-623del,\N,\N,23/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610511,3:193376035:CAAAAAAAAA>C,NM_130837.2:c.2332-631_2332-623del,\N,\N,23/30,Unknown significance,\N,intron_variant,6.242,\N,\N,OPA1
610512,3:193376048:AAAAAAG>A,NM_130837.2:c.2332-624_2332-619del,\N,\N,23/30,Unknown significance,\N,intron_variant,4.733,\N,\N,OPA1
610513,3:193376054:G>A,NM_130837.2:c.2332-622G>A,\N,\N,23/30,Unknown significance,\N,intron_variant,7.141,\N,\N,OPA1
610514,3:193376062:A>C,NM_130837.2:c.2332-614A>C,\N,\N,23/30,Unknown significance,\N,intron_variant,6.024,\N,\N,OPA1
610515,3:193376078:T>G,NM_130837.2:c.2332-598T>G,\N,\N,23/30,Unknown significance,\N,intron_variant,4.415,0.001,1KG_EAS_AF,OPA1
610516,3:193376164:A>T,NM_130837.2:c.2332-512A>T,\N,\N,23/30,Unknown significance,\N,intron_variant,7.222,0.0014,1KG_AMR_AF,OPA1
610517,3:193376167:T>G,NM_130837.2:c.2332-509T>G,\N,\N,23/30,Unknown significance,\N,intron_variant,10.01,\N,\N,OPA1
610518,3:193376226:TC>T,NM_130837.2:c.2332-449del,\N,\N,23/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610519,3:193376227:C>T,NM_130837.2:c.2332-449C>T,\N,\N,23/30,Benign,\N,intron_variant,3.179,0.4274,1KG_EUR_AF,OPA1
610520,3:193376245:G>T,NM_130837.2:c.2332-431G>T,\N,\N,23/30,Unknown significance,\N,intron_variant,7.772,\N,\N,OPA1
610521,3:193376253:G>T,NM_130837.2:c.2332-423G>T,\N,\N,23/30,Unknown significance,\N,intron_variant,11,\N,\N,OPA1
610522,3:193376273:C>G,NM_130837.2:c.2332-403C>G,\N,\N,23/30,Unknown significance,\N,intron_variant,8.809,0.0029,1KG_AMR_AF,OPA1
610523,3:193376290:A>G,NM_130837.2:c.2332-386A>G,\N,\N,23/30,Unknown significance,\N,intron_variant,0.84,\N,\N,OPA1
610524,3:193376298:G>A,NM_130837.2:c.2332-378G>A,\N,\N,23/30,Benign,\N,intron_variant,5.17,0.4264,1KG_EUR_AF,OPA1
610525,3:193376304:T>C,NM_130837.2:c.2332-372T>C,\N,\N,23/30,Unknown significance,\N,intron_variant,3.791,0.0008,1KG_AFR_AF,OPA1
610526,3:193376353:G>A,NM_130837.2:c.2332-323G>A,\N,\N,23/30,Benign,\N,intron_variant,4.818,0.1501,1KG_EUR_AF,OPA1
610527,3:193376411:T>G,NM_130837.2:c.2332-265T>G,\N,\N,23/30,Benign,\N,intron_variant,11.42,0.0265,1KG_AFR_AF,OPA1
610528,3:193376443:C>T,NM_130837.2:c.2332-233C>T,\N,\N,23/30,Unknown significance,\N,intron_variant,2.637,0.0008,1KG_AFR_AF,OPA1
610529,3:193376481:A>G,NM_130837.2:c.2332-195A>G,\N,\N,23/30,Unknown significance,\N,intron_variant,1.159,0.001,1KG_EAS_AF,OPA1
610530,3:193376501:A>G,NM_130837.2:c.2332-175A>G,\N,\N,23/30,Unknown significance,\N,intron_variant,7.886,\N,\N,OPA1
610531,3:193376504:A>T,NM_130837.2:c.2332-172A>T,\N,\N,23/30,Unknown significance,\N,intron_variant,5.581,\N,\N,OPA1
610532,3:193376526:G>A,NM_130837.2:c.2332-150G>A,\N,\N,23/30,Unknown significance,\N,intron_variant,3.099,0.002,1KG_EAS_AF,OPA1
610533,3:193376589:A>G,NM_130837.2:c.2332-87A>G,\N,\N,23/30,Unknown significance,\N,intron_variant,4.683,\N,\N,OPA1
610534,3:193376592:T>C,NM_130837.2:c.2332-84T>C,\N,\N,23/30,Benign,\N,intron_variant,2.359,0.0238,1KG_EAS_AF,OPA1
610535,3:193376626:A>C,NM_130837.2:c.2332-50A>C,\N,\N,23/30,Unknown significance,\N,intron_variant,1.527,0.001,1KG_SAS_AF,OPA1
610536,3:193376637:G>T,NM_130837.2:c.2332-39G>T,\N,\N,23/30,Unknown significance,\N,intron_variant,0.366,0.000174429,EXAC_AMR_AF,OPA1
610537,3:193376646:G>A,NM_130837.2:c.2332-30G>A,\N,\N,23/30,Unknown significance,\N,intron_variant,2.111,\N,\N,OPA1
610538,3:193376646:GT>G,NM_130837.2:c.2332-28del,\N,\N,23/30,Unknown significance,\N,intron_variant,1.532,0.000194212,EXAC_AFR_AF,OPA1
610539,3:193376650:G>A,NM_130837.2:c.2332-26G>A,\N,\N,23/30,Unknown significance,\N,intron_variant,4.505,0.000121581,EXAC_SAS_AF,OPA1
610540,3:193376652:T>G,NM_130837.2:c.2332-24T>G,\N,\N,23/30,Unknown significance,\N,intron_variant,6.454,0.000290529,EXAC_AFR_AF,OPA1
610541,3:193376657:C>A,NM_130837.2:c.2332-19C>A,\N,\N,23/30,Benign,\N,intron_variant,10.29,0.0061,1KG_AFR_AF,OPA1
610542,3:193376657:CTCT>C,NM_130837.2:c.2332-14_2332-12del,\N,\N,23/30,Unknown significance,\N,intron_variant,11.56,0.0000451331,EXAC_NFE_AF,OPA1
610543,3:193376668:A>T,NM_130837.2:c.2332-8A>T,\N,\N,23/30,Unknown significance,\N,splice_region_variant&intron_variant,11.36,\N,\N,OPA1
610544,3:193376673:C>T,NM_130837.2:c.2332-3C>T,\N,\N,23/30,Unknown significance,\N,splice_region_variant&intron_variant,15.79,0.0000964506,EXAC_AFR_AF,OPA1
610545,3:193376676:A>C,NM_130837.2:c.2332A>C,NP_570850.2:p.Arg778=,24/31,\N,Unknown significance,\N,splice_region_variant&synonymous_variant,11.42,0.0000150002,EXAC_NFE_AF,OPA1
610546,3:193376682:A>G,NM_130837.2:c.2338A>G,NP_570850.2:p.Ile780Val,24/31,\N,Unknown significance,\N,missense_variant,24.5,0.0000149948,EXAC_NFE_AF,OPA1
610547,3:193376690:C>T,NM_130837.2:c.2346C>T,NP_570850.2:p.His782=,24/31,\N,Unknown significance,\N,synonymous_variant,14.04,0.000192493,EXAC_AFR_AF,OPA1
610548,3:193376692:A>G,NM_015560.2:c.2183A>G,NP_056375.2:p.Asn728Ser,22/29,\N,Unknown significance,\N,missense_variant,24.9,0.0000149921,EXAC_NFE_AF,OPA1
610549,3:193376693:T>G,NM_130837.2:c.2349T>G,NP_570850.2:p.Asn783Lys,24/31,\N,Pathogenic,Optic atrophy 1,missense_variant,28.5,\N,\N,OPA1
610550,3:193376701:A>AAGAC,NM_130837.2:c.2358_2361dup,NP_570850.2:p.Ser789ProfsTer5,24/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,35,\N,\N,OPA1
610551,3:193376704:A>G,NM_015560.2:c.2195A>G,NP_056375.2:p.Asp732Gly,22/29,\N,Unknown significance,\N,missense_variant,32,\N,\N,OPA1
610552,3:193376706:C>T,NM_130837.2:c.2362C>T,NP_570850.2:p.Arg788Ter,24/31,\N,Pathogenic,Optic atrophy 1,stop_gained,44,\N,\N,OPA1
610553,3:193376729:A>G,NM_130837.2:c.2385A>G,NP_570850.2:p.Gln795=,24/31,\N,Unknown significance,\N,synonymous_variant,9.07,0.000192271,EXAC_AFR_AF,OPA1
610554,3:193376735:T>G,NM_130837.2:c.2391T>G,NP_570850.2:p.Asp797Glu,24/31,\N,Unknown significance,\N,missense_variant,22.7,0.000116279,EVS_EA_AF,OPA1
610555,3:193376741:T>A,NM_130837.2:c.2397T>A,NP_570850.2:p.Ala799=,24/31,\N,Unknown significance,\N,synonymous_variant,13.73,0.0000605767,EXAC_SAS_AF,OPA1
610556,3:193376760:G>A,NM_130837.2:c.2416G>A,NP_570850.2:p.Ala806Thr,24/31,\N,Unknown significance,\N,missense_variant,18.79,0.000116279,EVS_EA_AF,OPA1
610557,3:193376765:G>T,NM_130837.2:c.2421G>T,NP_570850.2:p.Leu807=,24/31,\N,Benign,\N,synonymous_variant,9.159,0.00110375,EXAC_OTH_AF,OPA1
610558,3:193376766:C>T,NM_130837.2:c.2422C>T,NP_570850.2:p.Gln808Ter,24/31,\N,Pathogenic,Dominant hereditary optic atrophy,stop_gained,52,\N,\N,OPA1
610559,3:193376773:G>A,NM_130837.2:c.2429G>A,NP_570850.2:p.Arg810His,24/31,\N,Unknown significance,\N,missense_variant,35,0.0000962649,EXAC_AFR_AF,OPA1
610560,3:193376780:G>A,NM_130837.2:c.2436G>A,NP_570850.2:p.Lys812=,24/31,\N,Unknown significance,\N,synonymous_variant,13.98,0.0000963948,EXAC_AFR_AF,OPA1
610561,3:193376781:G>A,NM_130837.2:c.2437G>A,NP_570850.2:p.Asp813Asn,24/31,\N,Unknown significance,\N,missense_variant,23.6,0.000060746,EXAC_SAS_AF,OPA1
610562,3:193376784:A>G,NM_130835.2:c.2332A>G,NP_570848.1:p.Thr778Ala,23/30,\N,Unknown significance,\N,missense_variant&splice_region_variant,19.38,0.000015082,EXAC_NFE_AF,OPA1
610563,3:193376787:A>G,NM_130837.2:c.2440+3A>G,\N,\N,24/30,Unknown significance,\N,splice_region_variant&intron_variant,14.6,0.000116904,EXAC_EAS_AF,OPA1
610564,3:193376797:A>C,NM_130837.2:c.2440+13A>C,\N,\N,24/30,Unknown significance,\N,intron_variant,0.348,0.00011798,EXAC_EAS_AF,OPA1
610565,3:193376798:C>T,NM_130837.2:c.2440+14C>T,\N,\N,24/30,Unknown significance,\N,intron_variant,0.205,0.0000610352,EXAC_SAS_AF,OPA1
610566,3:193376799:G>A,NM_130837.2:c.2440+15G>A,\N,\N,24/30,Unknown significance,\N,intron_variant,0.408,0.000152765,EXAC_FIN_AF,OPA1
610567,3:193376805:T>C,NM_130837.2:c.2440+21T>C,\N,\N,24/30,Unknown significance,\N,intron_variant,5.36,0.001,1KG_EAS_AF,OPA1
610568,3:193376807:G>A,NM_130837.2:c.2440+23G>A,\N,\N,24/30,Unknown significance,\N,intron_variant,12.81,0.0000611098,EXAC_SAS_AF,OPA1
610569,3:193376814:G>C,NM_130837.2:c.2440+30G>C,\N,\N,24/30,Unknown significance,\N,intron_variant,11.76,0.0000880127,EXAC_AMR_AF,OPA1
610570,3:193376816:G>A,NM_130837.2:c.2440+32G>A,\N,\N,24/30,Unknown significance,\N,intron_variant,13.22,0.0000153294,EXAC_NFE_AF,OPA1
610571,3:193376823:G>GTGGTGAAGGAGTCA,NM_130837.2:c.2440+41_2440+54dup,\N,\N,24/30,Unknown significance,\N,intron_variant,3.966,\N,\N,OPA1
610572,3:193376824:T>TG,NM_130837.2:c.2440+42dup,\N,\N,24/30,Unknown significance,\N,intron_variant,6.558,0.0000615385,EXAC_NFE_AF,OPA1
610573,3:193376826:G>A,NM_130837.2:c.2440+42G>A,\N,\N,24/30,Unknown significance,\N,intron_variant,4.799,0.000121095,EXAC_EAS_AF,OPA1
610574,3:193376851:A>G,NM_130837.2:c.2440+67A>G,\N,\N,24/30,Unknown significance,\N,intron_variant,5.044,\N,\N,OPA1
610575,3:193376854:A>T,NM_130837.2:c.2440+70A>T,\N,\N,24/30,Unknown significance,\N,intron_variant,0.546,0.0014,1KG_AMR_AF,OPA1
610576,3:193376874:C>T,NM_130837.2:c.2440+90C>T,\N,\N,24/30,Unknown significance,\N,intron_variant,7.734,\N,\N,OPA1
610577,3:193376900:T>C,NM_130837.2:c.2440+116T>C,\N,\N,24/30,Unknown significance,\N,intron_variant,6.902,\N,\N,OPA1
610578,3:193376906:C>T,NM_130837.2:c.2440+122C>T,\N,\N,24/30,Unknown significance,\N,intron_variant,3,0.0015,1KG_AFR_AF,OPA1
610579,3:193376907:G>A,NM_130837.2:c.2440+123G>A,\N,\N,24/30,Unknown significance,\N,intron_variant,1.16,\N,\N,OPA1
610580,3:193376911:A>G,NM_130837.2:c.2440+127A>G,\N,\N,24/30,Unknown significance,\N,intron_variant,2.135,0.0008,1KG_AFR_AF,OPA1
610581,3:193377016:G>A,NM_130837.2:c.2440+232G>A,\N,\N,24/30,Unknown significance,\N,intron_variant,4.264,0.0014,1KG_AMR_AF,OPA1
610582,3:193377021:A>C,NM_130837.2:c.2440+237A>C,\N,\N,24/30,Unknown significance,\N,intron_variant,4.675,0.001,1KG_EUR_AF,OPA1
610583,3:193377025:T>C,NM_130837.2:c.2440+241T>C,\N,\N,24/30,Unknown significance,\N,intron_variant,9.085,0.0008,1KG_AFR_AF,OPA1
610584,3:193377025:T>G,NM_130837.2:c.2440+241T>G,\N,\N,24/30,Unknown significance,\N,intron_variant,9.717,\N,\N,OPA1
610585,3:193377037:G>A,NM_130837.2:c.2441-234G>A,\N,\N,24/30,Benign,\N,intron_variant,4.976,0.4264,1KG_EUR_AF,OPA1
610586,3:193377040:A>G,NM_130837.2:c.2441-231A>G,\N,\N,24/30,Unknown significance,\N,intron_variant,3.597,0.001,1KG_EAS_AF|1KG_SAS_AF,OPA1
610587,3:193377050:T>G,NM_130837.2:c.2441-221T>G,\N,\N,24/30,Unknown significance,\N,intron_variant,3.388,\N,\N,OPA1
610588,3:193377067:A>T,NM_130837.2:c.2441-204A>T,\N,\N,24/30,Unknown significance,\N,intron_variant,11.98,\N,\N,OPA1
610589,3:193377091:A>G,NM_130837.2:c.2441-180A>G,\N,\N,24/30,Unknown significance,\N,intron_variant,0.509,0.001,1KG_EAS_AF,OPA1
610590,3:193377115:A>G,NM_130837.2:c.2441-156A>G,\N,\N,24/30,Benign,\N,intron_variant,1.527,0.0079,1KG_EAS_AF,OPA1
610591,3:193377122:A>G,NM_130837.2:c.2441-149A>G,\N,\N,24/30,Unknown significance,\N,intron_variant,3.298,0.0008,1KG_AFR_AF,OPA1
610592,3:193377131:A>G,NM_130837.2:c.2441-140A>G,\N,\N,24/30,Unknown significance,\N,intron_variant,4.228,0.001,1KG_SAS_AF,OPA1
610593,3:193377137:G>C,NM_130837.2:c.2441-134G>C,\N,\N,24/30,Benign,\N,intron_variant,0.147,0.0091,1KG_AFR_AF,OPA1
610594,3:193377137:G>GT,NM_130837.2:c.2441-128dup,\N,\N,24/30,Benign,\N,intron_variant,1.052,0.0308,1KG_EAS_AF,OPA1
610595,3:193377167:T>C,NM_130837.2:c.2441-104T>C,\N,\N,24/30,Unknown significance,\N,intron_variant,2.194,0.0008,1KG_AFR_AF,OPA1
610596,3:193377173:T>C,NM_130837.2:c.2441-98T>C,\N,\N,24/30,Benign,\N,intron_variant,1.408,0.1511,1KG_EUR_AF,OPA1
610597,3:193377184:A>G,NM_130837.2:c.2441-87A>G,\N,\N,24/30,Unknown significance,\N,intron_variant,4.947,0.0008,1KG_AFR_AF,OPA1
610598,3:193377204:C>A,NM_130837.2:c.2441-67C>A,\N,\N,24/30,Unknown significance,\N,intron_variant,5.516,\N,\N,OPA1
610599,3:193377222:G>A,NM_130837.2:c.2441-49G>A,\N,\N,24/30,Unknown significance,\N,intron_variant,2.208,0.000535619,EXAC_AFR_AF,OPA1
610600,3:193377224:G>T,NM_130837.2:c.2441-47G>T,\N,\N,24/30,Unknown significance,\N,intron_variant,1.982,0.002,1KG_EUR_AF,OPA1
610601,3:193377232:A>G,NM_130837.2:c.2441-39A>G,\N,\N,24/30,Unknown significance,\N,intron_variant,2.663,0.000387297,EXAC_EAS_AF,OPA1
610602,3:193377245:C>A,NM_130837.2:c.2441-26C>A,\N,\N,24/30,Unknown significance,\N,intron_variant,2.203,0.000104954,EXAC_SAS_AF,OPA1
610603,3:193377248:GATTA>G,NM_130837.2:c.2441-15_2441-12del,\N,\N,24/30,Unknown significance,\N,intron_variant,4.689,0.0000421124,EXAC_NFE_AF,OPA1
610604,3:193377252:A>G,NM_130837.2:c.2441-19A>G,\N,\N,24/30,Unknown significance,\N,intron_variant,1.762,0.000116306,EVS_EA_AF,OPA1
610605,3:193377254:T>C,NM_130837.2:c.2441-17T>C,\N,\N,24/30,Unknown significance,\N,intron_variant,3.571,0.000174459,EXAC_AMR_AF,OPA1
610606,3:193377257:A>AT,NM_130837.2:c.2441-5dup,\N,\N,24/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610607,3:193377257:AT>A,NM_130837.2:c.2441-5del,\N,\N,24/30,Unknown significance,\N,intron_variant,2.369,\N,\N,OPA1
610608,3:193377258:T>G,NM_130837.2:c.2441-13T>G,\N,\N,24/30,Unknown significance,\N,intron_variant,5.567,0.00010012,EXAC_SAS_AF,OPA1
610609,3:193377266:T>TC,NM_130837.2:c.2441-4dup,\N,\N,24/30,Unknown significance,\N,splice_region_variant&intron_variant,11.03,0.000676972,EXAC_NFE_AF,OPA1
610610,3:193377267:C>G,NM_130837.2:c.2441-4C>G,\N,\N,24/30,Unknown significance,\N,splice_region_variant&intron_variant,12.92,0.0000276778,EXAC_NFE_AF,OPA1
610611,3:193377282:A>G,NM_130837.2:c.2452A>G,NP_570850.2:p.Ile818Val,25/31,\N,Unknown significance,\N,missense_variant,23.1,0.0000212748,EXAC_NFE_AF,OPA1
610612,3:193377285:G>GA,NM_130837.2:c.2459dup,NP_570850.2:p.Asn820LysfsTer26,25/31,\N,Pathogenic,Optic atrophy,frameshift_variant,35,\N,\N,OPA1
610613,3:193377298:G>A,NM_130837.2:c.2468G>A,NP_570850.2:p.Gly823Asp,25/31,\N,Pathogenic,Optic atrophy 1,missense_variant,33,\N,\N,OPA1
610614,3:193377300:C>G,NM_130837.2:c.2470C>G,NP_570850.2:p.Pro824Ala,25/31,\N,Unknown significance,\N,missense_variant,27.8,0.000019044,EXAC_NFE_AF,OPA1
610615,3:193377308:GAAA>G,NM_130837.2:c.2481_2483del,NP_570850.2:p.Lys828del,25/31,\N,Unknown significance,\N,inframe_deletion,16.33,0.000168976,EXAC_FIN_AF,OPA1
610616,3:193377310:A>G,NM_130837.2:c.2480A>G,NP_570850.2:p.Lys827Arg,25/31,\N,Unknown significance,\N,missense_variant,19.05,0.000133298,EXAC_EAS_AF,OPA1
610617,3:193377314:G>A,NM_130837.2:c.2484G>A,NP_570850.2:p.Lys828=,25/31,\N,Unknown significance,\N,synonymous_variant,14.46,0.0008,1KG_AFR_AF,OPA1
610618,3:193377323:A>G,NM_130837.2:c.2493A>G,NP_570850.2:p.Leu831=,25/31,\N,Unknown significance,\N,synonymous_variant,11.38,0.000119617,EXAC_AFR_AF,OPA1
610619,3:193377326:C>A,NM_130837.2:c.2496C>A,NP_570850.2:p.Tyr832Ter,25/31,\N,Pathogenic,Optic atrophy & auditory neuropathy,stop_gained,42,\N,\N,OPA1
610620,3:193377336:C>T,NM_130837.2:c.2506C>T,NP_570850.2:p.Arg836Trp,25/31,\N,Pathogenic,Optic atrophy 1,missense_variant,35,0.0014,1KG_AMR_AF,OPA1
610621,3:193377336:C>G,NM_015560.2:c.2341C>G,NP_056375.2:p.Arg781Gly,23/29,\N,Unknown significance,\N,missense_variant,23.3,0.000116279,EVS_EA_AF,OPA1
610622,3:193377343:A>G,NM_130837.2:c.2513A>G,NP_570850.2:p.Gln838Arg,25/31,\N,Unknown significance,\N,missense_variant,19.29,0.0000197075,EXAC_NFE_AF,OPA1
610623,3:193377346:A>G,NM_130837.2:c.2516A>G,NP_570850.2:p.Glu839Gly,25/31,\N,Unknown significance,\N,missense_variant,31,0.0000199108,EXAC_NFE_AF,OPA1
610624,3:193377349:A>G,NM_130837.2:c.2519A>G,NP_570850.2:p.Gln840Arg,25/31,\N,Pathogenic,Optic atrophy 1,missense_variant&splice_region_variant,26.9,\N,\N,OPA1
610625,3:193377351:G>A,NM_130837.2:c.2520+1G>A,\N,\N,25/30,Pathogenic,Optic atrophy 1,splice_donor_variant,26.8,\N,\N,OPA1
610626,3:193377359:A>T,NM_130837.2:c.2520+9A>T,\N,\N,25/30,Unknown significance,\N,intron_variant,4.814,\N,\N,OPA1
610627,3:193377363:A>G,NM_130837.2:c.2520+13A>G,\N,\N,25/30,Unknown significance,\N,intron_variant,0.136,0.000453926,EVS_AA_AF,OPA1
610628,3:193377365:GTC>G,NM_130837.2:c.2520+19_2520+20del,\N,\N,25/30,Unknown significance,\N,intron_variant,2.376,0.000155909,EXAC_SAS_AF,OPA1
610629,3:193377378:T>A,NM_130837.2:c.2520+28T>A,\N,\N,25/30,Unknown significance,\N,intron_variant,0.618,0.000890076,EXAC_AMR_AF,OPA1
610630,3:193377378:T>C,NM_130837.2:c.2520+28T>C,\N,\N,25/30,Unknown significance,\N,intron_variant,0.2,0.000475522,EXAC_NFE_AF,OPA1
610631,3:193377379:G>A,NM_130837.2:c.2520+29G>A,\N,\N,25/30,Unknown significance,\N,intron_variant,3.77,0.000145349,EXAC_AFR_AF,OPA1
610632,3:193377385:A>G,NM_130837.2:c.2520+35A>G,\N,\N,25/30,Unknown significance,\N,intron_variant,1.964,0.0000822774,EXAC_SAS_AF,OPA1
610633,3:193377395:T>C,NM_130837.2:c.2520+45T>C,\N,\N,25/30,Unknown significance,\N,intron_variant,5.735,\N,\N,OPA1
610634,3:193377408:G>A,NM_130837.2:c.2520+58G>A,\N,\N,25/30,Unknown significance,\N,intron_variant,2.187,\N,\N,OPA1
610635,3:193377423:C>T,NM_130837.2:c.2520+73C>T,\N,\N,25/30,Unknown significance,\N,intron_variant,3.492,0.0014,1KG_AMR_AF,OPA1
610636,3:193377428:T>A,NM_130837.2:c.2520+78T>A,\N,\N,25/30,Unknown significance,\N,intron_variant,0.293,\N,\N,OPA1
610637,3:193377428:T>C,NM_130837.2:c.2520+78T>C,\N,\N,25/30,Unknown significance,\N,intron_variant,0.073,0.001,1KG_EUR_AF,OPA1
610638,3:193377441:C>T,NM_130837.2:c.2520+91C>T,\N,\N,25/30,Benign,\N,intron_variant,2.483,0.0169,1KG_EUR_AF,OPA1
610639,3:193377443:A>T,NM_130837.2:c.2520+93A>T,\N,\N,25/30,Unknown significance,\N,intron_variant,4.164,0.001,1KG_EAS_AF,OPA1
610640,3:193377487:T>C,NM_130837.2:c.2520+137T>C,\N,\N,25/30,Unknown significance,\N,intron_variant,9.932,0.001,1KG_SAS_AF,OPA1
610641,3:193377526:GT>G,NM_130837.2:c.2520+184del,\N,\N,25/30,Unknown significance,\N,intron_variant,17.52,\N,\N,OPA1
610642,3:193377542:G>T,NM_130837.2:c.2520+192G>T,\N,\N,25/30,Unknown significance,\N,intron_variant,11.73,\N,\N,OPA1
610643,3:193377558:A>C,NM_130837.2:c.2520+208A>C,\N,\N,25/30,Unknown significance,\N,intron_variant,1.194,0.0008,1KG_AFR_AF,OPA1
610644,3:193377562:CAAG>C,NM_130837.2:c.2520+214_2520+216del,\N,\N,25/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610645,3:193377650:A>ACAGGCC,NM_130837.2:c.2520+301_2520+306dup,\N,\N,25/30,Unknown significance,\N,intron_variant,8.307,0.0038,1KG_AFR_AF,OPA1
610646,3:193377675:C>A,NM_130837.2:c.2520+325C>A,\N,\N,25/30,Unknown significance,\N,intron_variant,12.08,0.0008,1KG_AFR_AF,OPA1
610647,3:193377692:T>C,NM_130837.2:c.2520+342T>C,\N,\N,25/30,Unknown significance,\N,intron_variant,14.19,0.0008,1KG_AFR_AF,OPA1
610648,3:193377713:T>TCGCTTGAGTTA,NM_130837.2:c.2520+364_2520+374dup,\N,\N,25/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610649,3:193377713:TCGCTTGAGTTA>T,NM_130837.2:c.2520+364_2520+374del,\N,\N,25/30,Benign,\N,intron_variant,4.657,0.4264,1KG_EUR_AF,OPA1
610650,3:193377714:C>A,NM_130837.2:c.2520+364C>A,\N,\N,25/30,Unknown significance,\N,intron_variant,2.187,\N,\N,OPA1
610651,3:193377720:A>G,NM_130837.2:c.2520+370A>G,\N,\N,25/30,Unknown significance,\N,intron_variant,2.748,\N,\N,OPA1
610652,3:193377722:T>A,NM_130837.2:c.2520+372T>A,\N,\N,25/30,Unknown significance,\N,intron_variant,6.929,\N,\N,OPA1
610653,3:193377723:T>A,NM_130837.2:c.2520+373T>A,\N,\N,25/30,Unknown significance,\N,intron_variant,5.533,\N,\N,OPA1
610654,3:193377724:A>C,NM_130837.2:c.2520+374A>C,\N,\N,25/30,Benign,\N,intron_variant,0.564,0.1831,1KG_AFR_AF,OPA1
610655,3:193377724:A>T,NM_130837.2:c.2520+374A>T,\N,\N,25/30,Unknown significance,\N,intron_variant,1.01,\N,\N,OPA1
610656,3:193377729:G>A,NM_130837.2:c.2520+379G>A,\N,\N,25/30,Unknown significance,\N,intron_variant,3.083,0.001,1KG_SAS_AF,OPA1
610657,3:193377732:C>T,NM_130837.2:c.2520+382C>T,\N,\N,25/30,Benign,\N,intron_variant,0.311,0.005,1KG_EAS_AF,OPA1
610658,3:193377737:C>G,NM_130837.2:c.2520+387C>G,\N,\N,25/30,Unknown significance,\N,intron_variant,4.02,\N,\N,OPA1
610659,3:193377778:T>A,NM_130837.2:c.2520+428T>A,\N,\N,25/30,Benign,\N,intron_variant,8.587,0.0367,1KG_EAS_AF,OPA1
610660,3:193377791:G>A,NM_130837.2:c.2520+441G>A,\N,\N,25/30,Unknown significance,\N,intron_variant,7.821,0.0029,1KG_AMR_AF,OPA1
610661,3:193377796:G>A,NM_130837.2:c.2520+446G>A,\N,\N,25/30,Unknown significance,\N,intron_variant,6.754,0.002,1KG_EAS_AF,OPA1
610662,3:193377798:G>A,NM_130837.2:c.2520+448G>A,\N,\N,25/30,Benign,\N,intron_variant,5.442,0.1369,1KG_AFR_AF,OPA1
610663,3:193377805:C>T,NM_130837.2:c.2520+455C>T,\N,\N,25/30,Unknown significance,\N,intron_variant,1.055,0.001,1KG_SAS_AF,OPA1
610664,3:193377870:C>T,NM_130837.2:c.2520+520C>T,\N,\N,25/30,Unknown significance,\N,intron_variant,1.244,0.0041,1KG_SAS_AF,OPA1
610665,3:193377871:G>A,NM_130837.2:c.2520+521G>A,\N,\N,25/30,Unknown significance,\N,intron_variant,0.142,0.0008,1KG_AFR_AF,OPA1
610666,3:193377872:A>C,NM_130837.2:c.2520+522A>C,\N,\N,25/30,Benign,\N,intron_variant,1.673,0.0091,1KG_AFR_AF,OPA1
610667,3:193377877:G>C,NM_130837.2:c.2520+527G>C,\N,\N,25/30,Unknown significance,\N,intron_variant,0.887,0.0015,1KG_AFR_AF,OPA1
610668,3:193377895:G>A,NM_130837.2:c.2520+545G>A,\N,\N,25/30,Unknown significance,\N,intron_variant,2.964,\N,\N,OPA1
610669,3:193377914:G>A,NM_130837.2:c.2520+564G>A,\N,\N,25/30,Unknown significance,\N,intron_variant,1.834,0.0008,1KG_AFR_AF,OPA1
610670,3:193377940:T>C,NM_130837.2:c.2520+590T>C,\N,\N,25/30,Unknown significance,\N,intron_variant,3.66,0.0031,1KG_SAS_AF,OPA1
610671,3:193377948:G>A,NM_130837.2:c.2520+598G>A,\N,\N,25/30,Benign,\N,intron_variant,1.089,0.0109,1KG_EAS_AF,OPA1
610672,3:193377955:G>C,NM_130837.2:c.2520+605G>C,\N,\N,25/30,Unknown significance,\N,intron_variant,0.066,\N,\N,OPA1
610673,3:193377961:A>G,NM_130837.2:c.2520+611A>G,\N,\N,25/30,Benign,\N,intron_variant,1.975,0.062,1KG_AFR_AF,OPA1
610674,3:193377992:A>G,NM_130837.2:c.2520+642A>G,\N,\N,25/30,Unknown significance,\N,intron_variant,3.998,\N,\N,OPA1
610675,3:193378001:A>G,NM_130837.2:c.2520+651A>G,\N,\N,25/30,Unknown significance,\N,intron_variant,3.372,\N,\N,OPA1
610676,3:193378030:C>T,NM_130837.2:c.2520+680C>T,\N,\N,25/30,Unknown significance,\N,intron_variant,1.085,\N,\N,OPA1
610677,3:193378054:T>C,NM_130837.2:c.2520+704T>C,\N,\N,25/30,Unknown significance,\N,intron_variant,4.727,0.0008,1KG_AFR_AF,OPA1
610678,3:193378069:T>G,NM_130837.2:c.2520+719T>G,\N,\N,25/30,Benign,\N,intron_variant,7.533,0.0061,1KG_AFR_AF,OPA1
610679,3:193378093:G>A,NM_130837.2:c.2520+743G>A,\N,\N,25/30,Benign,\N,intron_variant,2.417,0.0072,1KG_SAS_AF,OPA1
610680,3:193378126:A>C,NM_130837.2:c.2520+776A>C,\N,\N,25/30,Benign,\N,intron_variant,0.583,0.4264,1KG_EUR_AF,OPA1
610681,3:193378135:G>C,NM_130837.2:c.2520+785G>C,\N,\N,25/30,Unknown significance,\N,intron_variant,0.939,0.0008,1KG_AFR_AF,OPA1
610682,3:193378146:C>G,NM_130837.2:c.2520+796C>G,\N,\N,25/30,Unknown significance,\N,intron_variant,2.636,0.001,1KG_EUR_AF,OPA1
610683,3:193378195:C>T,NM_130837.2:c.2520+845C>T,\N,\N,25/30,Unknown significance,\N,intron_variant,9.79,0.001,1KG_EUR_AF,OPA1
610684,3:193378201:ATTTTC>A,NM_130837.2:c.2520+859_2520+863del,\N,\N,25/30,Benign,\N,intron_variant,8.566,0.0234,1KG_AFR_AF,OPA1
610685,3:193378238:T>A,NM_130837.2:c.2520+888T>A,\N,\N,25/30,Unknown significance,\N,intron_variant,14.34,\N,\N,OPA1
610686,3:193378244:A>G,NM_130837.2:c.2520+894A>G,\N,\N,25/30,Unknown significance,\N,intron_variant,13.64,\N,\N,OPA1
610687,3:193378271:A>G,NM_130837.2:c.2520+921A>G,\N,\N,25/30,Unknown significance,\N,intron_variant,1.674,\N,\N,OPA1
610688,3:193378292:T>C,NM_130837.2:c.2520+942T>C,\N,\N,25/30,Unknown significance,\N,intron_variant,1.595,0.0008,1KG_AFR_AF,OPA1
610689,3:193378309:C>A,NM_130837.2:c.2520+959C>A,\N,\N,25/30,Unknown significance,\N,intron_variant,6.758,0.001,1KG_EAS_AF,OPA1
610690,3:193378375:AT>A,NM_130837.2:c.2520+1032del,\N,\N,25/30,Benign,\N,intron_variant,5.267,0.1501,1KG_EUR_AF,OPA1
610691,3:193378417:C>G,NM_130837.2:c.2520+1067C>G,\N,\N,25/30,Unknown significance,\N,intron_variant,3.62,0.0008,1KG_AFR_AF,OPA1
610692,3:193378419:A>G,NM_130837.2:c.2520+1069A>G,\N,\N,25/30,Benign,\N,intron_variant,2.506,0.0092,1KG_SAS_AF,OPA1
610693,3:193378430:G>A,NM_130837.2:c.2520+1080G>A,\N,\N,25/30,Unknown significance,\N,intron_variant,2.957,\N,\N,OPA1
610694,3:193378440:T>TC,NM_130837.2:c.2520+1092dup,\N,\N,25/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610695,3:193378473:C>G,NM_130837.2:c.2520+1123C>G,\N,\N,25/30,Unknown significance,\N,intron_variant,2.794,\N,\N,OPA1
610696,3:193378490:AT>A,NM_130837.2:c.2520+1151del,\N,\N,25/30,Unknown significance,\N,intron_variant,0.138,\N,\N,OPA1
610697,3:193378491:T>A,NM_130837.2:c.2520+1141T>A,\N,\N,25/30,Unknown significance,\N,intron_variant,0.162,\N,\N,OPA1
610698,3:193378494:T>G,NM_130837.2:c.2520+1144T>G,\N,\N,25/30,Unknown significance,\N,intron_variant,0.03,0.0014,1KG_AMR_AF,OPA1
610699,3:193378497:T>C,NM_130837.2:c.2520+1147T>C,\N,\N,25/30,Unknown significance,\N,intron_variant,0.016,0.0014,1KG_AMR_AF,OPA1
610700,3:193378501:T>G,NM_130837.2:c.2520+1151T>G,\N,\N,25/30,Unknown significance,\N,intron_variant,0.248,\N,\N,OPA1
610701,3:193378503:G>T,NM_130837.2:c.2520+1153G>T,\N,\N,25/30,Unknown significance,\N,intron_variant,0.648,\N,\N,OPA1
610702,3:193378508:G>A,NM_130837.2:c.2520+1158G>A,\N,\N,25/30,Unknown significance,\N,intron_variant,1.197,\N,\N,OPA1
610703,3:193378509:A>T,NM_130837.2:c.2520+1159A>T,\N,\N,25/30,Unknown significance,\N,intron_variant,1.388,\N,\N,OPA1
610704,3:193378551:G>A,NM_130837.2:c.2520+1201G>A,\N,\N,25/30,Benign,\N,intron_variant,3.517,0.0133,1KG_SAS_AF,OPA1
610705,3:193378553:G>A,NM_130837.2:c.2520+1203G>A,\N,\N,25/30,Benign,\N,intron_variant,0.334,0.3211,1KG_SAS_AF,OPA1
610706,3:193378558:C>A,NM_130837.2:c.2520+1208C>A,\N,\N,25/30,Unknown significance,\N,intron_variant,3.592,0.001,1KG_EUR_AF,OPA1
610707,3:193378602:G>A,NM_130837.2:c.2520+1252G>A,\N,\N,25/30,Unknown significance,\N,intron_variant,13.25,0.002,1KG_EAS_AF,OPA1
610708,3:193378622:G>A,NM_130837.2:c.2520+1272G>A,\N,\N,25/30,Unknown significance,\N,intron_variant,12.62,0.0023,1KG_AFR_AF,OPA1
610709,3:193378624:G>T,NM_130837.2:c.2520+1274G>T,\N,\N,25/30,Unknown significance,\N,intron_variant,9.492,\N,\N,OPA1
610710,3:193378625:C>T,NM_130837.2:c.2520+1275C>T,\N,\N,25/30,Unknown significance,\N,intron_variant,12.3,\N,\N,OPA1
610711,3:193378627:G>A,NM_130837.2:c.2520+1277G>A,\N,\N,25/30,Unknown significance,\N,intron_variant,10.22,0.001,1KG_EAS_AF|1KG_EUR_AF,OPA1
610712,3:193378627:G>T,NM_130837.2:c.2520+1277G>T,\N,\N,25/30,Unknown significance,\N,intron_variant,9.329,\N,\N,OPA1
610713,3:193378657:C>G,NM_130837.2:c.2520+1307C>G,\N,\N,25/30,Unknown significance,\N,intron_variant,2.652,\N,\N,OPA1
610714,3:193378660:G>A,NM_130837.2:c.2520+1310G>A,\N,\N,25/30,Unknown significance,\N,intron_variant,4.367,0.001,1KG_EAS_AF,OPA1
610715,3:193378672:A>C,NM_130837.2:c.2520+1322A>C,\N,\N,25/30,Unknown significance,\N,intron_variant,1.666,\N,\N,OPA1
610716,3:193378674:GT>G,NM_130837.2:c.2520+1327del,\N,\N,25/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610717,3:193378748:A>G,NM_130837.2:c.2520+1398A>G,\N,\N,25/30,Unknown significance,\N,intron_variant,12.15,0.0029,1KG_AMR_AF,OPA1
610718,3:193378805:G>T,NM_130837.2:c.2520+1455G>T,\N,\N,25/30,Unknown significance,\N,intron_variant,1.061,0.001,1KG_EUR_AF,OPA1
610719,3:193378864:T>G,NM_130837.2:c.2520+1514T>G,\N,\N,25/30,Unknown significance,\N,intron_variant,2.174,0.0029,1KG_AMR_AF,OPA1
610720,3:193378921:G>GA,NM_130837.2:c.2520+1573dup,\N,\N,25/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610721,3:193378929:T>G,NM_130837.2:c.2520+1579T>G,\N,\N,25/30,Unknown significance,\N,intron_variant,13.98,\N,\N,OPA1
610722,3:193378950:G>C,NM_130837.2:c.2520+1600G>C,\N,\N,25/30,Unknown significance,\N,intron_variant,0.092,\N,\N,OPA1
610723,3:193378982:T>C,NM_130837.2:c.2521-1629T>C,\N,\N,25/30,Unknown significance,\N,intron_variant,3.852,\N,\N,OPA1
610724,3:193379008:C>G,NM_130837.2:c.2521-1603C>G,\N,\N,25/30,Benign,\N,intron_variant,4.138,0.6188,1KG_AFR_AF,OPA1
610725,3:193379015:G>A,NM_130837.2:c.2521-1596G>A,\N,\N,25/30,Unknown significance,\N,intron_variant,2.21,\N,\N,OPA1
610726,3:193379048:G>T,NM_130837.2:c.2521-1563G>T,\N,\N,25/30,Unknown significance,\N,intron_variant,3.335,0.001,1KG_EAS_AF,OPA1
610727,3:193379092:A>G,NM_130837.2:c.2521-1519A>G,\N,\N,25/30,Unknown significance,\N,intron_variant,3.103,0.0015,1KG_AFR_AF,OPA1
610728,3:193379107:A>G,NM_130837.2:c.2521-1504A>G,\N,\N,25/30,Unknown significance,\N,intron_variant,3.885,\N,\N,OPA1
610729,3:193379119:C>T,NM_130837.2:c.2521-1492C>T,\N,\N,25/30,Benign,\N,intron_variant,6.126,0.1369,1KG_AFR_AF,OPA1
610730,3:193379120:G>A,NM_130837.2:c.2521-1491G>A,\N,\N,25/30,Unknown significance,\N,intron_variant,1.756,\N,\N,OPA1
610731,3:193379194:C>T,NM_130837.2:c.2521-1417C>T,\N,\N,25/30,Unknown significance,\N,intron_variant,6.344,0.0029,1KG_AMR_AF,OPA1
610732,3:193379197:C>T,NM_130837.2:c.2521-1414C>T,\N,\N,25/30,Unknown significance,\N,intron_variant,4.773,0.001,1KG_EAS_AF,OPA1
610733,3:193379234:A>C,NM_130837.2:c.2521-1377A>C,\N,\N,25/30,Unknown significance,\N,intron_variant,4.571,0.001,1KG_EAS_AF,OPA1
610734,3:193379258:C>G,NM_130837.2:c.2521-1353C>G,\N,\N,25/30,Unknown significance,\N,intron_variant,2.2,\N,\N,OPA1
610735,3:193379261:G>C,NM_130837.2:c.2521-1350G>C,\N,\N,25/30,Benign,\N,intron_variant,0.544,0.0257,1KG_AFR_AF,OPA1
610736,3:193379314:C>G,NM_130837.2:c.2521-1297C>G,\N,\N,25/30,Unknown significance,\N,intron_variant,3.538,0.001,1KG_EUR_AF,OPA1
610737,3:193379317:A>G,NM_130837.2:c.2521-1294A>G,\N,\N,25/30,Unknown significance,\N,intron_variant,4.434,0.0008,1KG_AFR_AF,OPA1
610738,3:193379320:G>A,NM_130837.2:c.2521-1291G>A,\N,\N,25/30,Benign,\N,intron_variant,5.484,0.0053,1KG_AFR_AF,OPA1
610739,3:193379366:T>TA,NM_130837.2:c.2521-1242dup,\N,\N,25/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610740,3:193379375:G>GTTTC,NM_130837.2:c.2521-1236_2521-1235insTTTC,\N,\N,25/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610741,3:193379377:A>G,NM_130837.2:c.2521-1234A>G,\N,\N,25/30,Unknown significance,\N,intron_variant,13.57,\N,\N,OPA1
610742,3:193379381:C>A,NM_130837.2:c.2521-1230C>A,\N,\N,25/30,Unknown significance,\N,intron_variant,13.7,\N,\N,OPA1
610743,3:193379384:T>A,NM_130837.2:c.2521-1227T>A,\N,\N,25/30,Unknown significance,\N,intron_variant,13.79,\N,\N,OPA1
610744,3:193379387:C>T,NM_130837.2:c.2521-1224C>T,\N,\N,25/30,Unknown significance,\N,intron_variant,14.54,0.0015,1KG_AFR_AF,OPA1
610745,3:193379388:T>A,NM_130837.2:c.2521-1223T>A,\N,\N,25/30,Unknown significance,\N,intron_variant,15.17,0.004,1KG_EAS_AF,OPA1
610746,3:193379390:A>C,NM_130837.2:c.2521-1221A>C,\N,\N,25/30,Unknown significance,\N,intron_variant,13.08,\N,\N,OPA1
610747,3:193379396:A>T,NM_130837.2:c.2521-1215A>T,\N,\N,25/30,Unknown significance,\N,intron_variant,1.406,0.0041,1KG_SAS_AF,OPA1
610748,3:193379456:G>A,NM_130837.2:c.2521-1155G>A,\N,\N,25/30,Unknown significance,\N,intron_variant,1.342,\N,\N,OPA1
610749,3:193379509:G>C,NM_130837.2:c.2521-1102G>C,\N,\N,25/30,Unknown significance,\N,intron_variant,8.721,0.0014,1KG_AMR_AF,OPA1
610750,3:193379514:C>T,NM_130837.2:c.2521-1097C>T,\N,\N,25/30,Unknown significance,\N,intron_variant,4.799,\N,\N,OPA1
610751,3:193379553:G>A,NM_130837.2:c.2521-1058G>A,\N,\N,25/30,Benign,\N,intron_variant,0.373,0.1369,1KG_AFR_AF,OPA1
610752,3:193379555:A>G,NM_130837.2:c.2521-1056A>G,\N,\N,25/30,Unknown significance,\N,intron_variant,3.06,0.001,1KG_EAS_AF,OPA1
610753,3:193379560:G>A,NM_130837.2:c.2521-1051G>A,\N,\N,25/30,Unknown significance,\N,intron_variant,4.439,\N,\N,OPA1
610754,3:193379581:A>G,NM_130837.2:c.2521-1030A>G,\N,\N,25/30,Benign,\N,intron_variant,1.851,0.062,1KG_AFR_AF,OPA1
610755,3:193379595:A>T,NM_130837.2:c.2521-1016A>T,\N,\N,25/30,Unknown significance,\N,intron_variant,1.77,0.0014,1KG_AMR_AF,OPA1
610756,3:193379647:A>C,NM_130837.2:c.2521-964A>C,\N,\N,25/30,Benign,\N,intron_variant,6.27,0.0061,1KG_SAS_AF,OPA1
610757,3:193379759:T>G,NM_130837.2:c.2521-852T>G,\N,\N,25/30,Benign,\N,intron_variant,6.365,0.1369,1KG_AFR_AF,OPA1
610758,3:193379790:A>T,NM_130837.2:c.2521-821A>T,\N,\N,25/30,Unknown significance,\N,intron_variant,2.69,\N,\N,OPA1
610759,3:193379792:A>G,NM_130837.2:c.2521-819A>G,\N,\N,25/30,Benign,\N,intron_variant,4.915,0.0367,1KG_EAS_AF,OPA1
610760,3:193379803:C>CA,NM_130837.2:c.2521-799dup,\N,\N,25/30,Unknown significance,\N,intron_variant,5.915,\N,\N,OPA1
610761,3:193379803:CA>C,NM_130837.2:c.2521-799del,\N,\N,25/30,Benign,\N,intron_variant,7.023,0.0386,1KG_AFR_AF,OPA1
610762,3:193379814:A>T,NM_130837.2:c.2521-797A>T,\N,\N,25/30,Unknown significance,\N,intron_variant,0.565,0.0014,1KG_AMR_AF,OPA1
610763,3:193379819:G>C,NM_130837.2:c.2521-792G>C,\N,\N,25/30,Unknown significance,\N,intron_variant,0.405,0.001,1KG_EAS_AF,OPA1
610764,3:193379824:G>T,NM_130837.2:c.2521-787G>T,\N,\N,25/30,Unknown significance,\N,intron_variant,0.061,\N,\N,OPA1
610765,3:193379851:T>G,NM_130837.2:c.2521-760T>G,\N,\N,25/30,Benign,\N,intron_variant,5.975,0.0159,1KG_EAS_AF,OPA1
610766,3:193379852:AATTT>A,NM_130837.2:c.2521-753_2521-750del,\N,\N,25/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610767,3:193379867:A>T,NM_130837.2:c.2521-744A>T,\N,\N,25/30,Unknown significance,\N,intron_variant,0.925,\N,\N,OPA1
610768,3:193379902:A>G,NM_130837.2:c.2521-709A>G,\N,\N,25/30,Unknown significance,\N,intron_variant,3.174,\N,\N,OPA1
610769,3:193379912:G>T,NM_130837.2:c.2521-699G>T,\N,\N,25/30,Unknown significance,\N,intron_variant,0.378,0.001,1KG_EUR_AF,OPA1
610770,3:193380003:G>A,NM_130837.2:c.2521-608G>A,\N,\N,25/30,Unknown significance,\N,intron_variant,2.587,\N,\N,OPA1
610771,3:193380041:A>G,NM_130837.2:c.2521-570A>G,\N,\N,25/30,Unknown significance,\N,intron_variant,8.286,\N,\N,OPA1
610772,3:193380059:A>G,NM_130837.2:c.2521-552A>G,\N,\N,25/30,Unknown significance,\N,intron_variant,2.018,0.001,1KG_EAS_AF,OPA1
610773,3:193380067:C>T,NM_130837.2:c.2521-544C>T,\N,\N,25/30,Unknown significance,\N,intron_variant,2.58,0.0045,1KG_AFR_AF,OPA1
610774,3:193380084:G>A,NM_130837.2:c.2521-527G>A,\N,\N,25/30,Benign,\N,intron_variant,2.952,0.0061,1KG_SAS_AF,OPA1
610775,3:193380086:A>AC,NM_130837.2:c.2521-523dup,\N,\N,25/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610776,3:193380170:C>A,NM_130837.2:c.2521-441C>A,\N,\N,25/30,Unknown significance,\N,intron_variant,2.72,0.001,1KG_EAS_AF,OPA1
610777,3:193380209:T>A,NM_130837.2:c.2521-402T>A,\N,\N,25/30,Unknown significance,\N,intron_variant,1.532,0.0031,1KG_SAS_AF,OPA1
610778,3:193380224:C>G,NM_130837.2:c.2521-387C>G,\N,\N,25/30,Unknown significance,\N,intron_variant,1.542,\N,\N,OPA1
610779,3:193380239:T>G,NM_130837.2:c.2521-372T>G,\N,\N,25/30,Unknown significance,\N,intron_variant,3.67,0.001,1KG_EAS_AF,OPA1
610780,3:193380253:T>C,NM_130837.2:c.2521-358T>C,\N,\N,25/30,Unknown significance,\N,intron_variant,6.682,\N,\N,OPA1
610781,3:193380277:C>G,NM_130837.2:c.2521-334C>G,\N,\N,25/30,Unknown significance,\N,intron_variant,12.64,0.001,1KG_EAS_AF,OPA1
610782,3:193380280:C>T,NM_130837.2:c.2521-331C>T,\N,\N,25/30,Unknown significance,\N,intron_variant,9.091,0.001,1KG_EAS_AF|1KG_SAS_AF,OPA1
610783,3:193380286:A>T,NM_130837.2:c.2521-325A>T,\N,\N,25/30,Unknown significance,\N,intron_variant,17.78,\N,\N,OPA1
610784,3:193380301:A>C,NM_130837.2:c.2521-310A>C,\N,\N,25/30,Unknown significance,\N,intron_variant,2.822,\N,\N,OPA1
610785,3:193380306:G>A,NM_130837.2:c.2521-305G>A,\N,\N,25/30,Unknown significance,\N,intron_variant,3.339,\N,\N,OPA1
610786,3:193380375:G>C,NM_130837.2:c.2521-236G>C,\N,\N,25/30,Unknown significance,\N,intron_variant,1.564,\N,\N,OPA1
610787,3:193380397:C>T,NM_130837.2:c.2521-214C>T,\N,\N,25/30,Unknown significance,\N,intron_variant,1.186,\N,\N,OPA1
610788,3:193380430:G>A,NM_130837.2:c.2521-181G>A,\N,\N,25/30,Unknown significance,\N,intron_variant,6.911,0.0029,1KG_AMR_AF,OPA1
610789,3:193380450:GC>G,NM_130837.2:c.2521-159del,\N,\N,25/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610790,3:193380452:CG>C,NM_130837.2:c.2521-155del,\N,\N,25/30,Benign,\N,intron_variant,0.596,0.4264,1KG_EUR_AF,OPA1
610791,3:193380463:G>GT,NM_130837.2:c.2521-146dup,\N,\N,25/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610792,3:193380475:GTTTC>G,NM_130837.2:c.2521-129_2521-126del,\N,\N,25/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610793,3:193380529:T>C,NM_130837.2:c.2521-82T>C,\N,\N,25/30,Unknown significance,\N,intron_variant,6.692,0.002,1KG_EAS_AF,OPA1
610794,3:193380550:T>C,NM_130837.2:c.2521-61T>C,\N,\N,25/30,Unknown significance,\N,intron_variant,7.591,0.002,1KG_EUR_AF,OPA1
610795,3:193380561:C>G,NM_130837.2:c.2521-50C>G,\N,\N,25/30,Unknown significance,\N,intron_variant,3.157,0,EXAC_ALL_AF|EXAC_AFR_AF|EXAC_AMR_AF|EXAC_EAS_AF|EXAC_FIN_AF|EXAC_NFE_AF|EXAC_OTH_AF|EXAC_SAS_AF,OPA1
610796,3:193380561:C>T,NM_130837.2:c.2521-50C>T,\N,\N,25/30,Unknown significance,\N,intron_variant,4.377,0.001,1KG_EAS_AF,OPA1
610797,3:193380565:A>G,NM_130837.2:c.2521-46A>G,\N,\N,25/30,Unknown significance,\N,intron_variant,5.453,0.00068089,EVS_AA_AF,OPA1
610798,3:193380566:A>G,NM_130837.2:c.2521-45A>G,\N,\N,25/30,Unknown significance,\N,intron_variant,3.172,0.000116306,EVS_EA_AF,OPA1
610799,3:193380570:A>G,NM_130837.2:c.2521-41A>G,\N,\N,25/30,Unknown significance,\N,intron_variant,0.557,0.0015,1KG_AFR_AF,OPA1
610800,3:193380575:C>T,NM_130837.2:c.2521-36C>T,\N,\N,25/30,Unknown significance,\N,intron_variant,9.586,0.0001146,EXAC_AMR_AF,OPA1
610801,3:193380579:C>A,NM_130837.2:c.2521-32C>A,\N,\N,25/30,Unknown significance,\N,intron_variant,11.49,0.001,1KG_EUR_AF,OPA1
610802,3:193380579:C>G,NM_130837.2:c.2521-32C>G,\N,\N,25/30,Unknown significance,\N,intron_variant,9.24,0.000226963,EVS_AA_AF,OPA1
610803,3:193380579:C>T,NM_130837.2:c.2521-32C>T,\N,\N,25/30,Unknown significance,\N,intron_variant,10.3,0.0000194553,EXAC_NFE_AF,OPA1
610804,3:193380584:C>T,NM_130837.2:c.2521-27C>T,\N,\N,25/30,Unknown significance,\N,intron_variant,11.74,0.0008,1KG_AFR_AF,OPA1
610805,3:193380590:C>G,NM_130837.2:c.2521-21C>G,\N,\N,25/30,Unknown significance,\N,intron_variant,9.992,0.000139821,EXAC_SAS_AF,OPA1
610806,3:193380595:T>A,NM_130837.2:c.2521-16T>A,\N,\N,25/30,Benign,\N,intron_variant,10.13,0.005,1KG_EAS_AF,OPA1
610807,3:193380619:CA>C,NM_130837.2:c.2531del,NP_570850.2:p.Asn844MetfsTer11,26/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,35,\N,\N,OPA1
610808,3:193380621:A>G,NM_130837.2:c.2531A>G,NP_570850.2:p.Asn844Ser,26/31,\N,Unknown significance,\N,missense_variant,14,0.001,1KG_EUR_AF,OPA1
610809,3:193380634:T>A,NM_130837.2:c.2544T>A,NP_570850.2:p.Asn848Lys,26/31,\N,Unknown significance,\N,missense_variant,17.78,0.000352609,EXAC_EAS_AF,OPA1
610810,3:193380644:A>T,NM_130837.2:c.2554A>T,NP_570850.2:p.Lys852Ter,26/31,\N,Pathogenic,Optic atrophy,stop_gained,47,\N,\N,OPA1
610811,3:193380647:A>G,NM_130837.2:c.2557A>G,NP_570850.2:p.Met853Val,26/31,\N,Unknown significance,\N,missense_variant,21.8,0.000096637,EXAC_AFR_AF,OPA1
610812,3:193380651:T>A,NM_130837.2:c.2561T>A,NP_570850.2:p.Leu854Ter,26/31,\N,Pathogenic,Optic atrophy 1,stop_gained,39,\N,\N,OPA1
610813,3:193380667:G>A,NM_130837.2:c.2577G>A,NP_570850.2:p.Glu859=,26/31,\N,Unknown significance,\N,synonymous_variant,10.4,0.0000150448,EXAC_NFE_AF,OPA1
610814,3:193380682:T>C,NM_130837.2:c.2592T>C,NP_570850.2:p.Leu864=,26/31,\N,Unknown significance,\N,synonymous_variant,2.402,0.000465116,EVS_EA_AF,OPA1
610815,3:193380683:G>A,NM_130837.2:c.2593G>A,NP_570850.2:p.Ala865Thr,26/31,\N,Unknown significance,\N,missense_variant,17.05,0.0000870777,EXAC_AMR_AF,OPA1
610816,3:193380688:T>C,NM_130837.2:c.2598T>C,NP_570850.2:p.Ser866=,26/31,\N,Unknown significance,\N,synonymous_variant,8.773,0.0008,1KG_AFR_AF,OPA1
610817,3:193380695:A>G,NM_130837.2:c.2605A>G,NP_570850.2:p.Ile869Val,26/31,\N,Unknown significance,\N,missense_variant,11.22,0.00110375,EXAC_OTH_AF,OPA1
610818,3:193380700:C>T,NM_130837.2:c.2610C>T,NP_570850.2:p.Thr870=,26/31,\N,Unknown significance,\N,synonymous_variant,13.97,0.00153965,EXAC_AFR_AF,OPA1
610819,3:193380703:A>T,NM_130837.2:c.2613A>T,NP_570850.2:p.Thr871=,26/31,\N,Unknown significance,\N,synonymous_variant,0.386,0.0000962279,EXAC_AFR_AF,OPA1
610820,3:193380707:C>T,NM_130837.2:c.2617C>T,NP_570850.2:p.Arg873Trp,26/31,\N,Unknown significance,\N,missense_variant,35,0.000116279,EVS_EA_AF,OPA1
610821,3:193380712:G>A,NM_130837.2:c.2622G>A,NP_570850.2:p.Lys874=,26/31,\N,Unknown significance,\N,synonymous_variant,14.74,0.000173671,EXAC_AMR_AF,OPA1
610822,3:193380718:T>TG,NM_130837.2:c.2629dup,NP_570850.2:p.Glu877GlyfsTer13,26/31,\N,Unknown significance,\N,frameshift_variant,\N,\N,\N,OPA1
610823,3:193380720:A>T,NM_130837.2:c.2630A>T,NP_570850.2:p.Glu877Val,26/31,\N,Unknown significance,\N,missense_variant,25.3,0.000226963,EVS_AA_AF,OPA1
610824,3:193380722:T>C,NM_130837.2:c.2632T>C,NP_570850.2:p.Ser878Pro,26/31,\N,Unknown significance,\N,missense_variant,22.7,0.000226963,EVS_AA_AF,OPA1
610825,3:193380723:C>A,NM_130837.2:c.2633C>A,NP_570850.2:p.Ser878Tyr,26/31,\N,Pathogenic,Optic atrophy 1,missense_variant,23.9,\N,\N,OPA1
610826,3:193380725:C>T,NM_130837.2:c.2635C>T,NP_570850.2:p.Arg879Ter,26/31,\N,Pathogenic,Optic atrophy 1,stop_gained,46,\N,\N,OPA1
610827,3:193380726:G>A,NM_130837.2:c.2636G>A,NP_570850.2:p.Arg879Gln,26/31,\N,Likely benign,\N,missense_variant,23.9,0.00110375,EXAC_OTH_AF,OPA1
610828,3:193380730:A>C,NM_130837.2:c.2640A>C,NP_570850.2:p.Gly880=,26/31,\N,Unknown significance,\N,synonymous_variant,7.467,0.0000150069,EXAC_NFE_AF,OPA1
610829,3:193380734:G>A,NM_130837.2:c.2644G>A,NP_570850.2:p.Glu882Lys,26/31,\N,Unknown significance,\N,missense_variant,27.1,0.0000600294,EXAC_NFE_AF,OPA1
610830,3:193380737:G>A,NM_015560.2:c.2482G>A,NP_056375.2:p.Val828Ile,24/29,\N,Unknown significance,\N,missense_variant,23.9,0.0000150092,EXAC_NFE_AF,OPA1
610831,3:193380751:G>C,NM_130837.2:c.2661G>C,NP_570850.2:p.Leu887Phe,26/31,\N,Pathogenic,Optic atrophy,missense_variant&splice_region_variant,17.34,\N,\N,OPA1
610832,3:193380752:G>T,NM_130837.2:c.2661+1G>T,\N,\N,26/30,Pathogenic,Optic atrophy 1,splice_donor_variant,27,\N,\N,OPA1
610833,3:193380753:T>C,NM_130837.2:c.2661+2T>C,\N,\N,26/30,Pathogenic,Optic atrophy 1,splice_donor_variant,25.1,\N,\N,OPA1
610834,3:193380755:AT>GTAAC,NM_130837.2:c.2661+4_2661+5delinsGTAAC,\N,\N,26/30,Pathogenic,Optic atrophy,splice_region_variant&intron_variant,\N,\N,\N,OPA1
610835,3:193380755:A>G,NM_130837.2:c.2661+4A>G,\N,\N,26/30,Pathogenic,Optic atrophy 1,splice_region_variant&intron_variant,14.38,\N,\N,OPA1
610836,3:193380763:T>C,NM_130837.2:c.2661+12T>C,\N,\N,26/30,Unknown significance,\N,intron_variant,8.097,0.00110619,EXAC_OTH_AF,OPA1
610837,3:193380764:G>C,NM_130837.2:c.2661+13G>C,\N,\N,26/30,Unknown significance,\N,intron_variant,6.935,0.0000451074,EXAC_NFE_AF,OPA1
610838,3:193380766:T>C,NM_130837.2:c.2661+15T>C,\N,\N,26/30,Unknown significance,\N,intron_variant,6.465,0.0000150362,EXAC_NFE_AF,OPA1
610839,3:193380772:G>A,NM_130837.2:c.2661+21G>A,\N,\N,26/30,Unknown significance,\N,intron_variant,3.98,0.000226963,EVS_AA_AF,OPA1
610840,3:193380772:G>C,NM_130837.2:c.2661+21G>C,\N,\N,26/30,Unknown significance,\N,intron_variant,0.908,0.000121595,EXAC_SAS_AF,OPA1
610841,3:193380776:G>C,NM_130837.2:c.2661+25G>C,\N,\N,26/30,Unknown significance,\N,intron_variant,1.72,0.0000987557,EXAC_AFR_AF,OPA1
610842,3:193380778:A>C,NM_130837.2:c.2661+27A>C,\N,\N,26/30,Unknown significance,\N,intron_variant,2.137,0.0000150589,EXAC_NFE_AF,OPA1
610843,3:193380778:A>G,NM_130837.2:c.2661+27A>G,\N,\N,26/30,Unknown significance,\N,intron_variant,4.869,0.0000301178,EXAC_NFE_AF,OPA1
610844,3:193380817:C>T,NM_130837.2:c.2661+66C>T,\N,\N,26/30,Unknown significance,\N,intron_variant,8.208,\N,\N,OPA1
610845,3:193380821:A>G,NM_130837.2:c.2661+70A>G,\N,\N,26/30,Benign,\N,intron_variant,3.962,0.0061,1KG_AFR_AF,OPA1
610846,3:193380828:A>C,NM_130837.2:c.2661+77A>C,\N,\N,26/30,Unknown significance,\N,intron_variant,1.143,0.0015,1KG_AFR_AF,OPA1
610847,3:193380837:T>C,NM_130837.2:c.2661+86T>C,\N,\N,26/30,Unknown significance,\N,intron_variant,2.429,\N,\N,OPA1
610848,3:193380851:T>A,NM_130837.2:c.2661+100T>A,\N,\N,26/30,Unknown significance,\N,intron_variant,7.132,0.002,1KG_EAS_AF,OPA1
610849,3:193380865:G>A,NM_130837.2:c.2661+114G>A,\N,\N,26/30,Unknown significance,\N,intron_variant,1.243,0.002,1KG_EUR_AF,OPA1
610850,3:193380869:A>T,NM_130837.2:c.2661+118A>T,\N,\N,26/30,Unknown significance,\N,intron_variant,5.94,\N,\N,OPA1
610851,3:193380870:C>A,NM_130837.2:c.2661+119C>A,\N,\N,26/30,Benign,\N,intron_variant,7.223,0.0099,1KG_EAS_AF,OPA1
610852,3:193380876:C>T,NM_130837.2:c.2661+125C>T,\N,\N,26/30,Unknown significance,\N,intron_variant,10.04,\N,\N,OPA1
610853,3:193380878:G>A,NM_130837.2:c.2661+127G>A,\N,\N,26/30,Unknown significance,\N,intron_variant,7.628,0.0015,1KG_AFR_AF,OPA1
610854,3:193380907:G>A,NM_130837.2:c.2661+156G>A,\N,\N,26/30,Unknown significance,\N,intron_variant,7.922,0.0023,1KG_AFR_AF,OPA1
610855,3:193380962:T>C,NM_130837.2:c.2661+211T>C,\N,\N,26/30,Unknown significance,\N,intron_variant,4.441,\N,\N,OPA1
610856,3:193380968:A>G,NM_130837.2:c.2661+217A>G,\N,\N,26/30,Unknown significance,\N,intron_variant,2.554,\N,\N,OPA1
610857,3:193380983:T>A,NM_130837.2:c.2661+232T>A,\N,\N,26/30,Unknown significance,\N,intron_variant,9.029,\N,\N,OPA1
610858,3:193380984:T>C,NM_130837.2:c.2661+233T>C,\N,\N,26/30,Unknown significance,\N,intron_variant,6.663,0.001,1KG_EUR_AF,OPA1
610859,3:193381010:T>G,NM_130837.2:c.2661+259T>G,\N,\N,26/30,Unknown significance,\N,intron_variant,5.539,0.0014,1KG_AMR_AF,OPA1
610860,3:193381024:G>T,NM_130837.2:c.2661+273G>T,\N,\N,26/30,Unknown significance,\N,intron_variant,0.69,0.0008,1KG_AFR_AF,OPA1
610861,3:193381025:A>G,NM_130837.2:c.2661+274A>G,\N,\N,26/30,Unknown significance,\N,intron_variant,1.916,\N,\N,OPA1
610862,3:193381033:G>A,NM_130837.2:c.2661+282G>A,\N,\N,26/30,Unknown significance,\N,intron_variant,1.037,0.0045,1KG_AFR_AF,OPA1
610863,3:193381052:C>T,NM_130837.2:c.2661+301C>T,\N,\N,26/30,Unknown significance,\N,intron_variant,4.896,0.0008,1KG_AFR_AF,OPA1
610864,3:193381057:C>T,NM_130837.2:c.2661+306C>T,\N,\N,26/30,Benign,\N,intron_variant,3.97,0.1369,1KG_AFR_AF,OPA1
610865,3:193381060:T>A,NM_130837.2:c.2661+309T>A,\N,\N,26/30,Unknown significance,\N,intron_variant,7.823,0.001,1KG_SAS_AF,OPA1
610866,3:193381079:G>A,NM_130837.2:c.2661+328G>A,\N,\N,26/30,Unknown significance,\N,intron_variant,10.58,\N,\N,OPA1
610867,3:193381087:G>A,NM_130837.2:c.2661+336G>A,\N,\N,26/30,Unknown significance,\N,intron_variant,9.922,0.001,1KG_EUR_AF,OPA1
610868,3:193381106:A>G,NM_130837.2:c.2661+355A>G,\N,\N,26/30,Benign,\N,intron_variant,3.58,0.0265,1KG_AFR_AF,OPA1
610869,3:193381222:A>G,NM_130837.2:c.2661+471A>G,\N,\N,26/30,Benign,\N,intron_variant,3.213,0.0083,1KG_AFR_AF,OPA1
610870,3:193381245:G>A,NM_130837.2:c.2661+494G>A,\N,\N,26/30,Unknown significance,\N,intron_variant,2.534,0.0015,1KG_AFR_AF,OPA1
610871,3:193381258:C>A,NM_130837.2:c.2661+507C>A,\N,\N,26/30,Unknown significance,\N,intron_variant,4.215,\N,\N,OPA1
610872,3:193381259:T>G,NM_130837.2:c.2661+508T>G,\N,\N,26/30,Unknown significance,\N,intron_variant,3.437,\N,\N,OPA1
610873,3:193381260:A>G,NM_130837.2:c.2661+509A>G,\N,\N,26/30,Unknown significance,\N,intron_variant,4.915,\N,\N,OPA1
610874,3:193381261:C>T,NM_130837.2:c.2661+510C>T,\N,\N,26/30,Unknown significance,\N,intron_variant,0.61,\N,\N,OPA1
610875,3:193381271:T>C,NM_130837.2:c.2661+520T>C,\N,\N,26/30,Benign,\N,intron_variant,7.3,0.0477,1KG_AFR_AF,OPA1
610876,3:193381281:T>C,NM_130837.2:c.2661+530T>C,\N,\N,26/30,Unknown significance,\N,intron_variant,5.97,0.001,1KG_SAS_AF,OPA1
610877,3:193381291:G>A,NM_130837.2:c.2661+540G>A,\N,\N,26/30,Unknown significance,\N,intron_variant,4.948,\N,\N,OPA1
610878,3:193381302:T>G,NM_130837.2:c.2661+551T>G,\N,\N,26/30,Unknown significance,\N,intron_variant,6.996,0.0045,1KG_AFR_AF,OPA1
610879,3:193381315:T>TTA,NM_130837.2:c.2661+564_2661+565insTA,\N,\N,26/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610880,3:193381351:A>G,NM_130837.2:c.2661+600A>G,\N,\N,26/30,Unknown significance,\N,intron_variant,0.92,\N,\N,OPA1
610881,3:193381388:A>G,NM_130837.2:c.2661+637A>G,\N,\N,26/30,Unknown significance,\N,intron_variant,3.773,0.0008,1KG_AFR_AF,OPA1
610882,3:193381416:A>G,NM_130837.2:c.2661+665A>G,\N,\N,26/30,Benign,\N,intron_variant,7.643,0.0153,1KG_SAS_AF,OPA1
610883,3:193381426:G>C,NM_130837.2:c.2661+675G>C,\N,\N,26/30,Unknown significance,\N,intron_variant,0.528,\N,\N,OPA1
610884,3:193381427:A>C,NM_130837.2:c.2661+676A>C,\N,\N,26/30,Unknown significance,\N,intron_variant,0.981,\N,\N,OPA1
610885,3:193381538:T>C,NM_130837.2:c.2661+787T>C,\N,\N,26/30,Unknown significance,\N,intron_variant,9.824,\N,\N,OPA1
610886,3:193381542:A>C,NM_130837.2:c.2661+791A>C,\N,\N,26/30,Unknown significance,\N,intron_variant,9.778,\N,\N,OPA1
610887,3:193381551:C>T,NM_130837.2:c.2661+800C>T,\N,\N,26/30,Benign,\N,intron_variant,2.812,0.0091,1KG_AFR_AF,OPA1
610888,3:193381560:G>C,NM_130837.2:c.2661+809G>C,\N,\N,26/30,Unknown significance,\N,intron_variant,6.957,0.0045,1KG_AFR_AF,OPA1
610889,3:193381591:A>G,NM_130837.2:c.2661+840A>G,\N,\N,26/30,Unknown significance,\N,intron_variant,6.689,0.0014,1KG_AMR_AF,OPA1
610890,3:193381631:A>G,NM_130837.2:c.2661+880A>G,\N,\N,26/30,Unknown significance,\N,intron_variant,9.1,\N,\N,OPA1
610891,3:193381650:C>A,NM_130837.2:c.2661+899C>A,\N,\N,26/30,Unknown significance,\N,intron_variant,5.621,0.0029,1KG_AMR_AF,OPA1
610892,3:193381661:A>C,NM_130837.2:c.2661+910A>C,\N,\N,26/30,Unknown significance,\N,intron_variant,0.501,\N,\N,OPA1
610893,3:193381679:A>G,NM_130837.2:c.2661+928A>G,\N,\N,26/30,Unknown significance,\N,intron_variant,6.214,0.0014,1KG_AMR_AF,OPA1
610894,3:193381680:T>C,NM_130837.2:c.2661+929T>C,\N,\N,26/30,Unknown significance,\N,intron_variant,5.31,0.0015,1KG_AFR_AF,OPA1
610895,3:193381698:T>C,NM_130837.2:c.2661+947T>C,\N,\N,26/30,Unknown significance,\N,intron_variant,1.721,0.001,1KG_EAS_AF,OPA1
610896,3:193381705:G>A,NM_130837.2:c.2661+954G>A,\N,\N,26/30,Benign,\N,intron_variant,2.013,0.0069,1KG_EAS_AF,OPA1
610897,3:193381711:A>C,NM_130837.2:c.2662-958A>C,\N,\N,26/30,Unknown significance,\N,intron_variant,4.062,0.001,1KG_EAS_AF,OPA1
610898,3:193381718:G>A,NM_130837.2:c.2662-951G>A,\N,\N,26/30,Unknown significance,\N,intron_variant,2.252,\N,\N,OPA1
610899,3:193381755:C>T,NM_130837.2:c.2662-914C>T,\N,\N,26/30,Unknown significance,\N,intron_variant,1.037,0.0008,1KG_AFR_AF,OPA1
610900,3:193381756:G>A,NM_130837.2:c.2662-913G>A,\N,\N,26/30,Unknown significance,\N,intron_variant,2.363,0.0015,1KG_AFR_AF,OPA1
610901,3:193381768:G>A,NM_130837.2:c.2662-901G>A,\N,\N,26/30,Unknown significance,\N,intron_variant,0.259,0.001,1KG_EAS_AF,OPA1
610902,3:193381824:C>T,NM_130837.2:c.2662-845C>T,\N,\N,26/30,Unknown significance,\N,intron_variant,2.847,0.0014,1KG_AMR_AF,OPA1
610903,3:193381828:AT>A,NM_130837.2:c.2662-831del,\N,\N,26/30,Benign,\N,intron_variant,6.176,0.0053,1KG_AFR_AF,OPA1
610904,3:193381829:T>A,NM_130837.2:c.2662-840T>A,\N,\N,26/30,Unknown significance,\N,intron_variant,8.064,\N,\N,OPA1
610905,3:193381852:A>G,NM_130837.2:c.2662-817A>G,\N,\N,26/30,Unknown significance,\N,intron_variant,2.22,0.003,1KG_EAS_AF,OPA1
610906,3:193381864:A>G,NM_130837.2:c.2662-805A>G,\N,\N,26/30,Unknown significance,\N,intron_variant,1.247,\N,\N,OPA1
610907,3:193381915:T>C,NM_130837.2:c.2662-754T>C,\N,\N,26/30,Benign,\N,intron_variant,3.043,0.4284,1KG_EUR_AF,OPA1
610908,3:193381947:G>A,NM_130837.2:c.2662-722G>A,\N,\N,26/30,Unknown significance,\N,intron_variant,3.581,\N,\N,OPA1
610909,3:193382066:T>C,NM_130837.2:c.2662-603T>C,\N,\N,26/30,Unknown significance,\N,intron_variant,2.257,0.0029,1KG_AMR_AF,OPA1
610910,3:193382075:CT>C,NM_130837.2:c.2662-590del,\N,\N,26/30,Unknown significance,\N,intron_variant,1.953,\N,\N,OPA1
610911,3:193382115:A>ATGTTT,NM_130837.2:c.2662-552_2662-548dup,\N,\N,26/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610912,3:193382138:A>G,NM_130837.2:c.2662-531A>G,\N,\N,26/30,Benign,\N,intron_variant,2.142,0.5666,1KG_AFR_AF,OPA1
610913,3:193382149:CA>C,NM_130837.2:c.2662-514del,\N,\N,26/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610914,3:193382151:A>G,NM_130837.2:c.2662-518A>G,\N,\N,26/30,Benign,\N,intron_variant,5.455,0.0265,1KG_AFR_AF,OPA1
610915,3:193382184:A>C,NM_130837.2:c.2662-485A>C,\N,\N,26/30,Unknown significance,\N,intron_variant,0.266,0.0029,1KG_AMR_AF,OPA1
610916,3:193382277:A>G,NM_130837.2:c.2662-392A>G,\N,\N,26/30,Unknown significance,\N,intron_variant,0.311,\N,\N,OPA1
610917,3:193382341:T>C,NM_130837.2:c.2662-328T>C,\N,\N,26/30,Unknown significance,\N,intron_variant,0.75,0.004,1KG_EAS_AF,OPA1
610918,3:193382351:C>A,NM_130837.2:c.2662-318C>A,\N,\N,26/30,Unknown significance,\N,intron_variant,4.526,0.0015,1KG_AFR_AF,OPA1
610919,3:193382369:G>T,NM_130837.2:c.2662-300G>T,\N,\N,26/30,Unknown significance,\N,intron_variant,1.85,\N,\N,OPA1
610920,3:193382370:G>A,NM_130837.2:c.2662-299G>A,\N,\N,26/30,Benign,\N,intron_variant,2.961,0.5862,1KG_AFR_AF,OPA1
610921,3:193382402:T>C,NM_130837.2:c.2662-267T>C,\N,\N,26/30,Benign,\N,intron_variant,1.864,0.0053,1KG_AFR_AF,OPA1
610922,3:193382416:T>C,NM_130837.2:c.2662-253T>C,\N,\N,26/30,Unknown significance,\N,intron_variant,3.215,0.0014,1KG_AMR_AF,OPA1
610923,3:193382427:G>GT,NM_130837.2:c.2662-239dup,\N,\N,26/30,Unknown significance,\N,intron_variant,2.319,0.003,1KG_AFR_AF,OPA1
610924,3:193382435:C>G,NM_130837.2:c.2662-234C>G,\N,\N,26/30,Benign,\N,intron_variant,3.48,0.0089,1KG_EUR_AF,OPA1
610925,3:193382454:C>T,NM_130837.2:c.2662-215C>T,\N,\N,26/30,Unknown significance,\N,intron_variant,5.832,\N,\N,OPA1
610926,3:193382537:A>G,NM_130837.2:c.2662-132A>G,\N,\N,26/30,Unknown significance,\N,intron_variant,0.041,0.002,1KG_EAS_AF,OPA1
610927,3:193382550:C>T,NM_130837.2:c.2662-119C>T,\N,\N,26/30,Unknown significance,\N,intron_variant,7.851,0.0008,1KG_AFR_AF,OPA1
610928,3:193382568:TTAAC>T,NM_130837.2:c.2662-99_2662-96del,\N,\N,26/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610929,3:193382584:A>G,NM_130837.2:c.2662-85A>G,\N,\N,26/30,Unknown significance,\N,intron_variant,1.344,\N,\N,OPA1
610930,3:193382613:GT>G,NM_130837.2:c.2662-54del,\N,\N,26/30,Unknown significance,\N,intron_variant,5.936,\N,\N,OPA1
610931,3:193382622:C>G,NM_130837.2:c.2662-47C>G,\N,\N,26/30,Unknown significance,\N,intron_variant,2.312,0.0000151575,EXAC_NFE_AF,OPA1
610932,3:193382629:A>G,NM_130837.2:c.2662-40A>G,\N,\N,26/30,Unknown significance,\N,intron_variant,2.443,\N,\N,OPA1
610933,3:193382630:A>C,NM_130837.2:c.2662-39A>C,\N,\N,26/30,Unknown significance,\N,intron_variant,0.221,0.0000151501,EXAC_NFE_AF,OPA1
610934,3:193382634:A>G,NM_130837.2:c.2662-35A>G,\N,\N,26/30,Unknown significance,\N,intron_variant,4.707,0.0000151556,EXAC_NFE_AF,OPA1
610935,3:193382636:A>G,NM_130837.2:c.2662-33A>G,\N,\N,26/30,Unknown significance,\N,intron_variant,5.451,0.000227273,EVS_AA_AF,OPA1
610936,3:193382638:T>A,NM_130837.2:c.2662-31T>A,\N,\N,26/30,Unknown significance,\N,intron_variant,8.625,0.000121625,EXAC_SAS_AF,OPA1
610937,3:193382644:T>A,NM_130837.2:c.2662-25T>A,\N,\N,26/30,Unknown significance,\N,intron_variant,6.545,0.000116496,EVS_EA_AF,OPA1
610938,3:193382651:T>C,NM_130837.2:c.2662-18T>C,\N,\N,26/30,Unknown significance,\N,intron_variant,0.488,0.00111857,EXAC_OTH_AF,OPA1
610939,3:193382657:T>C,NM_130837.2:c.2662-12T>C,\N,\N,26/30,Unknown significance,\N,intron_variant,6.309,0.0000151469,EXAC_NFE_AF,OPA1
610940,3:193382660:T>A,NM_130837.2:c.2662-9T>A,\N,\N,26/30,Unknown significance,\N,intron_variant,16.18,0.000117096,EXAC_EAS_AF,OPA1
610941,3:193382675:G>A,NM_015560.2:c.2503G>A,NP_056375.2:p.Asp835Asn,25/29,\N,Unknown significance,\N,missense_variant,23.8,\N,\N,OPA1
610942,3:193382679:C>T,NM_130837.2:c.2672C>T,NP_570850.2:p.Thr891Ile,27/31,\N,Unknown significance,\N,missense_variant,23.7,0.0000151556,EXAC_NFE_AF,OPA1
610943,3:193382694:A>G,NM_130837.2:c.2687A>G,NP_570850.2:p.Tyr896Cys,27/31,\N,Pathogenic,Optic atrophy 1,missense_variant,28.2,\N,\N,OPA1
610944,3:193382703:A>G,NM_130837.2:c.2696A>G,NP_570850.2:p.His899Arg,27/31,\N,Unknown significance,\N,missense_variant,23,0.000243457,EXAC_SAS_AF,OPA1
610945,3:193382703:A>AT,NM_130837.2:c.2702dup,NP_570850.2:p.Leu901PhefsTer9,27/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,35,\N,\N,OPA1
610946,3:193382709:T>A,NM_130837.2:c.2702T>A,NP_570850.2:p.Leu901Ter,27/31,\N,Pathogenic,Optic neuropathy,stop_gained,43,\N,\N,OPA1
610947,3:193382716:A>G,NM_130837.2:c.2709A>G,NP_570850.2:p.Thr903=,27/31,\N,Unknown significance,\N,synonymous_variant,4.171,0.000227066,EVS_AA_AF,OPA1
610948,3:193382719:T>A,NM_130837.2:c.2712T>A,NP_570850.2:p.Ala904=,27/31,\N,Unknown significance,\N,synonymous_variant,12.39,0.0000303933,EXAC_NFE_AF,OPA1
610949,3:193382720:C>G,NM_130834.2:c.2602C>G,NP_570847.2:p.Leu868Val,26/30,\N,Unknown significance,\N,missense_variant,24.5,0.000117261,EXAC_EAS_AF,OPA1
610950,3:193382725:C>CA,NM_130837.2:c.2718_2719insA,NP_570850.2:p.His907ThrfsTer3,27/31,\N,Pathogenic,Optic atrophy,frameshift_variant,35,\N,\N,OPA1
610951,3:193382728:T>G,NM_130837.2:c.2721T>G,NP_570850.2:p.His907Gln,27/31,\N,Unknown significance,\N,missense_variant,8.898,0.0000152133,EXAC_NFE_AF,OPA1
610952,3:193382735:C>A,NM_130837.2:c.2728C>A,NP_570850.2:p.Leu910Ile,27/31,\N,Unknown significance,\N,missense_variant,24.4,0.0000608865,EXAC_SAS_AF,OPA1
610953,3:193382736:T>G,NM_130834.2:c.2618T>G,NP_570847.2:p.Leu873Arg,26/30,\N,Unknown significance,\N,missense_variant,23.4,0.000116577,EVS_EA_AF,OPA1
610954,3:193382738:T>A,NM_130837.2:c.2731T>A,NP_570850.2:p.Cys911Ser,27/31,\N,Unknown significance,\N,missense_variant,27.9,0.0000609162,EXAC_SAS_AF,OPA1
610955,3:193382741:C>T,NM_130837.2:c.2734C>T,NP_570850.2:p.Arg912Ter,27/31,\N,Pathogenic,Optic atrophy 1,stop_gained,46,\N,\N,OPA1
610956,3:193382754:A>G,NM_015560.2:c.2582A>G,NP_056375.2:p.Tyr861Cys,25/29,\N,Unknown significance,\N,missense_variant,29.1,0.0000152541,EXAC_NFE_AF,OPA1
610957,3:193382758:C>CA,NM_130837.2:c.2751_2752insA,NP_570850.2:p.Tyr918IlefsTer9,27/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,35,\N,\N,OPA1
610958,3:193382760:A>AC,NM_130837.2:c.2755dup,NP_570850.2:p.Gln919ProfsTer8,27/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,35,\N,\N,OPA1
610959,3:193382762:C>T,NM_130837.2:c.2755C>T,NP_570850.2:p.Gln919Ter,27/31,\N,Pathogenic,Optic atrophy 1,stop_gained,46,\N,\N,OPA1
610960,3:193382769:A>G,NM_130837.2:c.2762A>G,NP_570850.2:p.His921Arg,27/31,\N,Unknown significance,\N,missense_variant,18.77,0.001,1KG_EAS_AF,OPA1
610961,3:193382774:G>A,NM_130837.2:c.2767G>A,NP_570850.2:p.Val923Ile,27/31,\N,Likely benign,\N,missense_variant,21,0.0000882613,EXAC_AMR_AF,OPA1
610962,3:193382786:G>A,NM_130837.2:c.2778+1G>A,\N,\N,27/30,Pathogenic,Optic atrophy 1,splice_donor_variant,27.6,\N,\N,OPA1
610963,3:193382786:G>C,NM_130837.2:c.2778+1G>C,\N,\N,27/30,Pathogenic,Optic atrophy 1,splice_donor_variant,26.1,\N,\N,OPA1
610964,3:193382796:C>G,NM_130837.2:c.2778+11C>G,\N,\N,27/30,Benign,\N,intron_variant,13.16,0.1369,1KG_AFR_AF,OPA1
610965,3:193382796:C>CA,NM_130837.2:c.2778+16dup,\N,\N,27/30,Unknown significance,\N,intron_variant,13.77,0.0000154626,EXAC_NFE_AF,OPA1
610966,3:193382802:CAA>C,NM_130837.2:c.2778+19_2778+20del,\N,\N,27/30,Unknown significance,\N,intron_variant,\N,0.00112613,EXAC_OTH_AF,OPA1
610967,3:193382802:CAAAG>C,NM_130837.2:c.2778+19_2778+22del,\N,\N,27/30,Unknown significance,\N,intron_variant,12.37,0.000102585,EXAC_AFR_AF,OPA1
610968,3:193382818:T>G,NM_130837.2:c.2778+33T>G,\N,\N,27/30,Unknown significance,\N,intron_variant,4.043,0.0000468252,EXAC_NFE_AF,OPA1
610969,3:193382821:G>A,NM_130837.2:c.2778+36G>A,\N,\N,27/30,Unknown significance,\N,intron_variant,1.967,0.0000618659,EXAC_SAS_AF,OPA1
610970,3:193382823:A>C,NM_130837.2:c.2778+38A>C,\N,\N,27/30,Unknown significance,\N,intron_variant,1.803,0.00258882,EXAC_AMR_AF,OPA1
610971,3:193382824:A>G,NM_130837.2:c.2778+39A>G,\N,\N,27/30,Unknown significance,\N,intron_variant,2.735,0.000356952,EXAC_AMR_AF,OPA1
610972,3:193382830:G>A,NM_130837.2:c.2778+45G>A,\N,\N,27/30,Unknown significance,\N,intron_variant,1.678,0.000015866,EXAC_NFE_AF,OPA1
610973,3:193382836:A>ATATGCT,NM_130837.2:c.2778+54_2778+59dup,\N,\N,27/30,Unknown significance,\N,intron_variant,0.093,\N,\N,OPA1
610974,3:193382856:T>C,NM_130837.2:c.2778+71T>C,\N,\N,27/30,Unknown significance,\N,intron_variant,3.451,0.003,1KG_AFR_AF,OPA1
610975,3:193382891:T>C,NM_130837.2:c.2778+106T>C,\N,\N,27/30,Unknown significance,\N,intron_variant,8.629,0.001,1KG_SAS_AF,OPA1
610976,3:193382932:C>G,NM_130837.2:c.2778+147C>G,\N,\N,27/30,Unknown significance,\N,intron_variant,8.678,\N,\N,OPA1
610977,3:193382948:G>A,NM_130837.2:c.2778+163G>A,\N,\N,27/30,Unknown significance,\N,intron_variant,6.51,\N,\N,OPA1
610978,3:193382962:T>G,NM_130837.2:c.2778+177T>G,\N,\N,27/30,Unknown significance,\N,intron_variant,2.094,0.0008,1KG_AFR_AF,OPA1
610979,3:193382974:G>A,NM_130837.2:c.2778+189G>A,\N,\N,27/30,Unknown significance,\N,intron_variant,0.918,0.001,1KG_SAS_AF,OPA1
610980,3:193382990:A>G,NM_130837.2:c.2778+205A>G,\N,\N,27/30,Unknown significance,\N,intron_variant,2.287,0.0008,1KG_AFR_AF,OPA1
610981,3:193383003:T>C,NM_130837.2:c.2778+218T>C,\N,\N,27/30,Unknown significance,\N,intron_variant,2.681,\N,\N,OPA1
610982,3:193383043:A>T,NM_130837.2:c.2778+258A>T,\N,\N,27/30,Benign,\N,intron_variant,0.28,0.0144,1KG_AFR_AF,OPA1
610983,3:193383057:A>ATAAAG,NM_130837.2:c.2778+276_2778+277insGTAAA,\N,\N,27/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610984,3:193383058:T>TAAATA,NM_130837.2:c.2778+275_2778+279dup,\N,\N,27/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
610985,3:193383061:A>AG,NM_130837.2:c.2778+276_2778+277insG,\N,\N,27/30,Unknown significance,\N,intron_variant,0.104,\N,\N,OPA1
610986,3:193383061:A>ATAAAG,NM_130837.2:c.2778+279_2778+280insAGTAA,\N,\N,27/30,Benign,\N,intron_variant,0.073,0.6808,1KG_AFR_AF,OPA1
610987,3:193383061:A>G,NM_130837.2:c.2778+276A>G,\N,\N,27/30,Benign,\N,intron_variant,1.846,0.1936,1KG_AFR_AF,OPA1
610988,3:193383146:T>C,NM_130837.2:c.2778+361T>C,\N,\N,27/30,Benign,\N,intron_variant,1.029,0.0079,1KG_EAS_AF,OPA1
610989,3:193383164:G>A,NM_130837.2:c.2778+379G>A,\N,\N,27/30,Unknown significance,\N,intron_variant,1.658,0.001,1KG_EUR_AF,OPA1
610990,3:193383184:G>T,NM_130837.2:c.2778+399G>T,\N,\N,27/30,Benign,\N,intron_variant,0.331,0.0133,1KG_SAS_AF,OPA1
610991,3:193383188:C>G,NM_130837.2:c.2778+403C>G,\N,\N,27/30,Unknown significance,\N,intron_variant,1.255,\N,\N,OPA1
610992,3:193383201:A>G,NM_130837.2:c.2778+416A>G,\N,\N,27/30,Unknown significance,\N,intron_variant,7.429,0.001,1KG_EUR_AF,OPA1
610993,3:193383217:A>G,NM_130837.2:c.2778+432A>G,\N,\N,27/30,Unknown significance,\N,intron_variant,7.191,\N,\N,OPA1
610994,3:193383267:T>C,NM_130837.2:c.2778+482T>C,\N,\N,27/30,Benign,\N,intron_variant,2.623,0.0265,1KG_AFR_AF,OPA1
610995,3:193383315:A>C,NM_130837.2:c.2778+530A>C,\N,\N,27/30,Unknown significance,\N,intron_variant,0.262,0.0008,1KG_AFR_AF,OPA1
610996,3:193383319:C>G,NM_130837.2:c.2778+534C>G,\N,\N,27/30,Benign,\N,intron_variant,3.695,0.0265,1KG_AFR_AF,OPA1
610997,3:193383417:C>G,NM_130837.2:c.2778+632C>G,\N,\N,27/30,Unknown significance,\N,intron_variant,6.286,\N,\N,OPA1
610998,3:193383456:T>C,NM_130837.2:c.2779-629T>C,\N,\N,27/30,Unknown significance,\N,intron_variant,1.076,0.0031,1KG_SAS_AF,OPA1
610999,3:193383508:A>G,NM_130837.2:c.2779-577A>G,\N,\N,27/30,Unknown significance,\N,intron_variant,0.777,\N,\N,OPA1
611000,3:193383539:G>A,NM_130837.2:c.2779-546G>A,\N,\N,27/30,Unknown significance,\N,intron_variant,1.369,0.002,1KG_EAS_AF,OPA1
611001,3:193383539:G>GT,NM_130837.2:c.2779-538dup,\N,\N,27/30,Unknown significance,\N,intron_variant,1.471,\N,\N,OPA1
611002,3:193383637:G>A,NM_130837.2:c.2779-448G>A,\N,\N,27/30,Unknown significance,\N,intron_variant,5.02,\N,\N,OPA1
611003,3:193383641:C>A,NM_130837.2:c.2779-444C>A,\N,\N,27/30,Unknown significance,\N,intron_variant,4.95,\N,\N,OPA1
611004,3:193383672:G>A,NM_130837.2:c.2779-413G>A,\N,\N,27/30,Unknown significance,\N,intron_variant,5.651,\N,\N,OPA1
611005,3:193383706:A>G,NM_130837.2:c.2779-379A>G,\N,\N,27/30,Unknown significance,\N,intron_variant,3.701,\N,\N,OPA1
611006,3:193383723:T>C,NM_130837.2:c.2779-362T>C,\N,\N,27/30,Unknown significance,\N,intron_variant,2.335,\N,\N,OPA1
611007,3:193383763:A>G,NM_130837.2:c.2779-322A>G,\N,\N,27/30,Unknown significance,\N,intron_variant,2.317,\N,\N,OPA1
611008,3:193383776:G>T,NM_130837.2:c.2779-309G>T,\N,\N,27/30,Benign,\N,intron_variant,0.63,0.0189,1KG_AFR_AF,OPA1
611009,3:193383794:A>T,NM_130837.2:c.2779-291A>T,\N,\N,27/30,Unknown significance,\N,intron_variant,5.531,0.0008,1KG_AFR_AF,OPA1
611010,3:193383795:A>G,NM_130837.2:c.2779-290A>G,\N,\N,27/30,Benign,\N,intron_variant,7.979,0.0121,1KG_AFR_AF,OPA1
611011,3:193383823:A>G,NM_130837.2:c.2779-262A>G,\N,\N,27/30,Unknown significance,\N,intron_variant,2.782,\N,\N,OPA1
611012,3:193383860:A>G,NM_130837.2:c.2779-225A>G,\N,\N,27/30,Unknown significance,\N,intron_variant,5.696,0.0029,1KG_AMR_AF,OPA1
611013,3:193383880:G>C,NM_130837.2:c.2779-205G>C,\N,\N,27/30,Unknown significance,\N,intron_variant,0.788,\N,\N,OPA1
611014,3:193383936:T>C,NM_130837.2:c.2779-149T>C,\N,\N,27/30,Benign,\N,intron_variant,2.569,0.0265,1KG_AFR_AF,OPA1
611015,3:193383943:T>C,NM_130837.2:c.2779-142T>C,\N,\N,27/30,Benign,\N,intron_variant,0.956,0.5673,1KG_AFR_AF,OPA1
611016,3:193383948:A>G,NM_130837.2:c.2779-137A>G,\N,\N,27/30,Unknown significance,\N,intron_variant,1.505,\N,\N,OPA1
611017,3:193383973:A>G,NM_130837.2:c.2779-112A>G,\N,\N,27/30,Benign,\N,intron_variant,3.407,0.584,1KG_AFR_AF,OPA1
611018,3:193383997:T>C,NM_130837.2:c.2779-88T>C,\N,\N,27/30,Unknown significance,\N,intron_variant,0.642,\N,\N,OPA1
611019,3:193384027:C>T,NM_130837.2:c.2779-58C>T,\N,\N,27/30,Unknown significance,\N,intron_variant,1.093,\N,\N,OPA1
611020,3:193384033:T>C,NM_130837.2:c.2779-52T>C,\N,\N,27/30,Unknown significance,\N,intron_variant,4.208,0.000318878,EVS_AA_AF,OPA1
611021,3:193384056:C>G,NM_130837.2:c.2779-29C>G,\N,\N,27/30,Unknown significance,\N,intron_variant,9.677,0.0014,1KG_AMR_AF,OPA1
611022,3:193384070:T>C,NM_130837.2:c.2779-15T>C,\N,\N,27/30,Unknown significance,\N,intron_variant,1.97,0.001,1KG_EUR_AF,OPA1
611023,3:193384073:T>C,NM_130837.2:c.2779-12T>C,\N,\N,27/30,Unknown significance,\N,intron_variant,5.48,0.0000150029,EXAC_NFE_AF,OPA1
611024,3:193384076:A>G,NM_130837.2:c.2779-9A>G,\N,\N,27/30,Pathogenic,Optic atrophy 1,intron_variant,11.05,\N,\N,OPA1
611025,3:193384081:T>G,NM_130837.2:c.2779-4T>G,\N,\N,27/30,Unknown significance,\N,splice_region_variant&intron_variant,13.94,0.00075643,EXAC_FIN_AF,OPA1
611026,3:193384083:A>G,NM_130837.2:c.2779-2A>G,\N,\N,27/30,Pathogenic,Optic atrophy,splice_acceptor_variant,25.8,\N,\N,OPA1
611027,3:193384084:G>A,NM_130837.2:c.2779-1G>A,\N,\N,27/30,Pathogenic,Optic atrophy 1,splice_acceptor_variant,25.3,\N,\N,OPA1
611028,3:193384088:G>T,NM_130837.2:c.2782G>T,NP_570850.2:p.Glu928Ter,28/31,\N,Pathogenic,Optic atrophy,stop_gained,51,\N,\N,OPA1
611029,3:193384105:C>T,NM_130837.2:c.2799C>T,NP_570850.2:p.Val933=,28/31,\N,Unknown significance,\N,synonymous_variant,16.23,0.000014988,EXAC_NFE_AF,OPA1
611030,3:193384105:CTTGTT>C,NM_130837.2:c.2803_2807del,NP_570850.2:p.Phe935AlafsTer21,28/31,\N,Pathogenic,Optic atrophy,frameshift_variant,36,\N,\N,OPA1
611031,3:193384115:C>T,NM_130837.2:c.2809C>T,NP_570850.2:p.Arg937Cys,28/31,\N,Unknown significance,\N,missense_variant,34,0.000116279,EVS_EA_AF,OPA1
611032,3:193384116:G>T,NM_130837.2:c.2810G>T,NP_570850.2:p.Arg937Leu,28/31,\N,Pathogenic,Optic atrophy 1,missense_variant,35,\N,\N,OPA1
611033,3:193384118:A>G,NM_130837.2:c.2812A>G,NP_570850.2:p.Ile938Val,28/31,\N,Likely benign,\N,missense_variant,20.4,0.000226963,EVS_AA_AF,OPA1
611034,3:193384121:C>CAGTAT,NM_130837.2:c.2817_2818insTATAG,NP_570850.2:p.Arg940TyrfsTer12,28/31,\N,Unknown significance,\N,frameshift_variant,35,\N,\N,OPA1
611035,3:193384121:C>T,NM_130837.2:c.2815C>T,NP_570850.2:p.Gln939Ter,28/31,\N,Pathogenic,Optic atrophy 1,stop_gained,48,\N,\N,OPA1
611036,3:193384125:G>A,NM_130837.2:c.2819G>A,NP_570850.2:p.Arg940His,28/31,\N,Pathogenic,Optic atrophy,missense_variant,35,\N,\N,OPA1
611037,3:193384127:A>G,NM_015560.2:c.2656A>G,NP_056375.2:p.Met886Val,26/29,\N,Unknown significance,\N,missense_variant,20.3,\N,\N,OPA1
611038,3:193384131:T>C,NM_130837.2:c.2825T>C,NP_570850.2:p.Leu942Pro,28/31,\N,Pathogenic,Optic atrophy 1,missense_variant,29.9,\N,\N,OPA1
611039,3:193384141:C>T,NM_130837.2:c.2835C>T,NP_570850.2:p.Thr945=,28/31,\N,Unknown significance,\N,synonymous_variant,17.28,0.00110132,EXAC_OTH_AF,OPA1
611040,3:193384142:G>A,NM_130837.2:c.2836G>A,NP_570850.2:p.Ala946Thr,28/31,\N,Unknown significance,\N,missense_variant,27.5,0.0008,1KG_AFR_AF,OPA1
611041,3:193384146:A>C,NM_130837.2:c.2840A>C,NP_570850.2:p.Asn947Thr,28/31,\N,Unknown significance,\N,missense_variant,27.7,0.0000149849,EXAC_NFE_AF,OPA1
611042,3:193384148:A>G,NM_130837.2:c.2842A>G,NP_570850.2:p.Thr948Ala,28/31,\N,Unknown significance,\N,missense_variant,12.7,0.000060584,EXAC_SAS_AF,OPA1
611043,3:193384149:C>CT,NM_130837.2:c.2846dup,NP_570850.2:p.Leu949PhefsTer9,28/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,36,\N,\N,OPA1
611044,3:193384150:T>C,NM_130837.2:c.2844T>C,NP_570850.2:p.Thr948=,28/31,\N,Unknown significance,\N,synonymous_variant,9.235,0.0000149849,EXAC_NFE_AF,OPA1
611045,3:193384152:T>A,NM_130837.2:c.2846T>A,NP_570850.2:p.Leu949Ter,28/31,\N,Pathogenic,Optic atrophy,stop_gained,43,\N,\N,OPA1
611046,3:193384178:G>C,NM_130837.2:c.2872G>C,NP_570850.2:p.Val958Leu,28/31,\N,Pathogenic,Optic atrophy 1,missense_variant&splice_region_variant,22.2,\N,\N,OPA1
611047,3:193384179:G>C,NM_130837.2:c.2872+1G>C,\N,\N,28/30,Pathogenic,Optic atrophy,splice_donor_variant,26.4,\N,\N,OPA1
611048,3:193384180:T>C,NM_130837.2:c.2872+2T>C,\N,\N,28/30,Pathogenic,Optic atrophy 1,splice_donor_variant,25.8,\N,\N,OPA1
611049,3:193384180:T>G,NM_130837.2:c.2872+2T>G,\N,\N,28/30,Pathogenic,Optic atrophy 1,splice_donor_variant,26.7,\N,\N,OPA1
611050,3:193384188:A>G,NM_130837.2:c.2872+10A>G,\N,\N,28/30,Unknown significance,\N,intron_variant,13.47,\N,\N,OPA1
611051,3:193384193:G>C,NM_130837.2:c.2872+15G>C,\N,\N,28/30,Unknown significance,\N,intron_variant,10.18,0.00499319,EVS_AA_AF,OPA1
611052,3:193384193:G>T,NM_130837.2:c.2872+15G>T,\N,\N,28/30,Unknown significance,\N,intron_variant,10.95,0.000346981,EXAC_EAS_AF,OPA1
611053,3:193384202:C>G,NM_130837.2:c.2872+24C>G,\N,\N,28/30,Unknown significance,\N,intron_variant,6.047,\N,\N,OPA1
611054,3:193384202:CT>C,NM_130837.2:c.2872+26del,\N,\N,28/30,Unknown significance,\N,intron_variant,7.159,\N,\N,OPA1
611055,3:193384203:T>A,NM_130837.2:c.2872+25T>A,\N,\N,28/30,Benign,\N,intron_variant,7.627,0.524568,EXAC_FIN_AF,OPA1
611056,3:193384215:T>TA,NM_130837.2:c.2872+43dup,\N,\N,28/30,Unknown significance,\N,intron_variant,9.865,0.000117758,EXAC_EAS_AF,OPA1
611057,3:193384216:A>C,NM_130837.2:c.2872+38A>C,\N,\N,28/30,Unknown significance,\N,intron_variant,8.995,0.0000151851,EXAC_NFE_AF,OPA1
611058,3:193384221:A>T,NM_130837.2:c.2872+43A>T,\N,\N,28/30,Unknown significance,\N,intron_variant,10.88,\N,\N,OPA1
611059,3:193384222:T>C,NM_130837.2:c.2872+44T>C,\N,\N,28/30,Unknown significance,\N,intron_variant,12.32,0.000116279,EVS_EA_AF,OPA1
611060,3:193384224:A>C,NM_130837.2:c.2872+46A>C,\N,\N,28/30,Unknown significance,\N,intron_variant,11.5,0.000015306,EXAC_NFE_AF,OPA1
611061,3:193384285:T>C,NM_130837.2:c.2872+107T>C,\N,\N,28/30,Unknown significance,\N,intron_variant,9.591,\N,\N,OPA1
611062,3:193384301:G>A,NM_130837.2:c.2872+123G>A,\N,\N,28/30,Unknown significance,\N,intron_variant,4.298,\N,\N,OPA1
611063,3:193384303:G>A,NM_130837.2:c.2872+125G>A,\N,\N,28/30,Unknown significance,\N,intron_variant,1.007,0.001,1KG_SAS_AF,OPA1
611064,3:193384306:G>T,NM_130837.2:c.2872+128G>T,\N,\N,28/30,Unknown significance,\N,intron_variant,0.235,0.004,1KG_EAS_AF,OPA1
611065,3:193384315:G>A,NM_130837.2:c.2872+137G>A,\N,\N,28/30,Unknown significance,\N,intron_variant,2.728,\N,\N,OPA1
611066,3:193384342:C>T,NM_130837.2:c.2872+164C>T,\N,\N,28/30,Unknown significance,\N,intron_variant,0.921,\N,\N,OPA1
611067,3:193384356:C>T,NM_130837.2:c.2872+178C>T,\N,\N,28/30,Benign,\N,intron_variant,0.735,0.1566,1KG_AFR_AF,OPA1
611068,3:193384378:A>G,NM_130837.2:c.2872+200A>G,\N,\N,28/30,Unknown significance,\N,intron_variant,1.831,0.0008,1KG_AFR_AF,OPA1
611069,3:193384393:A>G,NM_130837.2:c.2872+215A>G,\N,\N,28/30,Unknown significance,\N,intron_variant,0.63,0.001,1KG_EAS_AF,OPA1
611070,3:193384406:A>G,NM_130837.2:c.2872+228A>G,\N,\N,28/30,Unknown significance,\N,intron_variant,0.031,\N,\N,OPA1
611071,3:193384435:G>A,NM_130837.2:c.2872+257G>A,\N,\N,28/30,Unknown significance,\N,intron_variant,2.867,0.001,1KG_EAS_AF,OPA1
611072,3:193384436:G>A,NM_130837.2:c.2872+258G>A,\N,\N,28/30,Unknown significance,\N,intron_variant,5.553,\N,\N,OPA1
611073,3:193384458:G>A,NM_130837.2:c.2872+280G>A,\N,\N,28/30,Unknown significance,\N,intron_variant,1.105,\N,\N,OPA1
611074,3:193384489:G>C,NM_130837.2:c.2872+311G>C,\N,\N,28/30,Unknown significance,\N,intron_variant,0.586,\N,\N,OPA1
611075,3:193384547:C>G,NM_130837.2:c.2872+369C>G,\N,\N,28/30,Unknown significance,\N,intron_variant,0.077,0.0008,1KG_AFR_AF,OPA1
611076,3:193384681:ACT>A,NM_130837.2:c.2873-275_2873-274del,\N,\N,28/30,Unknown significance,\N,intron_variant,6.314,\N,\N,OPA1
611077,3:193384707:A>G,NM_130837.2:c.2873-252A>G,\N,\N,28/30,Unknown significance,\N,intron_variant,6.259,0.003,1KG_EUR_AF,OPA1
611078,3:193384727:A>G,NM_130837.2:c.2873-232A>G,\N,\N,28/30,Unknown significance,\N,intron_variant,6.308,0.0008,1KG_AFR_AF,OPA1
611079,3:193384782:A>T,NM_130837.2:c.2873-177A>T,\N,\N,28/30,Unknown significance,\N,intron_variant,2.951,\N,\N,OPA1
611080,3:193384808:G>C,NM_130837.2:c.2873-151G>C,\N,\N,28/30,Unknown significance,\N,intron_variant,1.084,0.001,1KG_EUR_AF,OPA1
611081,3:193384811:T>C,NM_130837.2:c.2873-148T>C,\N,\N,28/30,Unknown significance,\N,intron_variant,2.856,\N,\N,OPA1
611082,3:193384863:T>TA,NM_130837.2:c.2873-90dup,\N,\N,28/30,Benign,\N,intron_variant,3.32,0.0234,1KG_AFR_AF,OPA1
611083,3:193384912:A>G,NM_130837.2:c.2873-47A>G,\N,\N,28/30,Unknown significance,\N,intron_variant,4.824,0.0000363148,EXAC_NFE_AF,OPA1
611084,3:193384916:A>T,NM_130837.2:c.2873-43A>T,\N,\N,28/30,Unknown significance,\N,intron_variant,10.14,0.000382848,EXAC_AFR_AF,OPA1
611085,3:193384923:C>T,NM_130837.2:c.2873-36C>T,\N,\N,28/30,Unknown significance,\N,intron_variant,1.229,0.000116306,EVS_EA_AF,OPA1
611086,3:193384924:G>A,NM_130837.2:c.2873-35G>A,\N,\N,28/30,Unknown significance,\N,intron_variant,1.722,0.001,1KG_EAS_AF,OPA1
611087,3:193384924:G>T,NM_130837.2:c.2873-35G>T,\N,\N,28/30,Unknown significance,\N,intron_variant,0.413,0.0000177847,EXAC_NFE_AF,OPA1
611088,3:193384925:A>G,NM_130837.2:c.2873-34A>G,\N,\N,28/30,Unknown significance,\N,intron_variant,4.111,0.0000352883,EXAC_NFE_AF,OPA1
611089,3:193384927:G>A,NM_130837.2:c.2873-32G>A,\N,\N,28/30,Unknown significance,\N,intron_variant,3.834,0.000232612,EVS_EA_AF,OPA1
611090,3:193384936:G>GT,NM_130837.2:c.2873-17dup,\N,\N,28/30,Unknown significance,\N,intron_variant,1.665,0.0000166456,EXAC_NFE_AF,OPA1
611091,3:193384945:CT>C,NM_130837.2:c.2873-11del,\N,\N,28/30,Unknown significance,\N,intron_variant,7.485,0.0000631313,EXAC_SAS_AF,OPA1
611092,3:193384949:C>G,NM_130837.2:c.2873-10C>G,\N,\N,28/30,Pathogenic,Optic atrophy 1,intron_variant,0.842,\N,\N,OPA1
611093,3:193384952:T>A,NM_130837.2:c.2873-7T>A,\N,\N,28/30,Unknown significance,\N,splice_region_variant&intron_variant,8.278,0.000015605,EXAC_NFE_AF,OPA1
611094,3:193384955:A>G,NM_130837.2:c.2873-4A>G,\N,\N,28/30,Unknown significance,\N,splice_region_variant&intron_variant,11.1,0.0000154569,EXAC_NFE_AF,OPA1
611095,3:193384956:CAGTT>C,NM_130837.2:c.2873_2876del,NP_570850.2:p.Val958GlyfsTer3,29/31,28/30,Pathogenic,Optic atrophy 1,splice_acceptor_variant&coding_sequence_variant,36,0.0000995818,EXAC_AFR_AF,OPA1
611096,3:193384957:A>T,NM_130837.2:c.2873-2A>T,\N,\N,28/30,Pathogenic,Optic atrophy 1,splice_acceptor_variant,24.2,\N,\N,OPA1
611097,3:193384958:G>T,NM_130837.2:c.2873-1G>T,\N,\N,28/30,Likely pathogenic,Optic atrophy 1,splice_acceptor_variant,25.7,\N,\N,OPA1
611098,3:193384960:T>C,NM_130837.2:c.2874T>C,NP_570850.2:p.Val958=,29/31,\N,Unknown significance,\N,splice_region_variant&synonymous_variant,10.53,0.0000152938,EXAC_NFE_AF,OPA1
611099,3:193384964:C>T,NM_130837.2:c.2878C>T,NP_570850.2:p.Arg960Ter,29/31,\N,Pathogenic,Optic atrophy 1,stop_gained,47,\N,\N,OPA1
611100,3:193384965:G>A,NM_130837.2:c.2879G>A,NP_570850.2:p.Arg960Gln,29/31,\N,Unknown significance,\N,missense_variant,32,0.0000970685,EXAC_AFR_AF,OPA1
611101,3:193384966:A>G,NM_130837.2:c.2880A>G,NP_570850.2:p.Arg960=,29/31,\N,Benign,\N,synonymous_variant,11.52,0.0061,1KG_AFR_AF,OPA1
611102,3:193384971:A>G,NM_130837.2:c.2885A>G,NP_570850.2:p.Glu962Gly,29/31,\N,Unknown significance,\N,missense_variant,34,\N,\N,OPA1
611103,3:193384972:GAA>G,NM_130837.2:c.2890_2891del,NP_570850.2:p.Asn964CysfsTer2,29/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,35,\N,\N,OPA1
611104,3:193384975:A>G,NM_130837.2:c.2889A>G,NP_570850.2:p.Lys963=,29/31,\N,Unknown significance,\N,synonymous_variant,4.759,0.000116279,EVS_EA_AF,OPA1
611105,3:193384977:ATGT>A,NM_130837.2:c.2893_2895del,NP_570850.2:p.Val965del,29/31,\N,Pathogenic,Optic atrophy,inframe_deletion,23.4,\N,\N,OPA1
611106,3:193384980:T>A,NM_130837.2:c.2894T>A,NP_570850.2:p.Val965Asp,29/31,\N,Pathogenic,Optic atrophy 1,missense_variant,34,\N,\N,OPA1
611107,3:193384988:G>T,NM_130837.2:c.2902G>T,NP_570850.2:p.Val968Leu,29/31,\N,Unknown significance,\N,missense_variant,32,\N,\N,OPA1
611108,3:193384990:A>G,NM_130837.2:c.2904A>G,NP_570850.2:p.Val968=,29/31,\N,Unknown significance,\N,synonymous_variant,10.79,0.0000864304,EXAC_AMR_AF,OPA1
611109,3:193384998:A>T,NM_015560.2:c.2747A>T,NP_056375.2:p.Asp916Val,27/29,\N,Unknown significance,\N,missense_variant,27.2,0.000121183,EXAC_SAS_AF,OPA1
611110,3:193385012:G>T,NM_130837.2:c.2926G>T,NP_570850.2:p.Gly976Cys,29/31,\N,Likely benign,\N,missense_variant,4.157,0.0000150173,EXAC_NFE_AF,OPA1
611111,3:193385015:GAGA>G,NM_130837.2:c.2936_2938del,NP_570850.2:p.Lys979del,29/31,\N,Unknown significance,\N,inframe_deletion,12.24,0.0000300336,EXAC_NFE_AF,OPA1
611112,3:193385015:G>A,NM_130837.2:c.2929G>A,NP_570850.2:p.Glu977Lys,29/31,\N,Unknown significance,\N,missense_variant,15.73,0.0000150168,EXAC_NFE_AF,OPA1
611113,3:193385017:G>A,NM_130837.2:c.2931G>A,NP_570850.2:p.Glu977=,29/31,\N,Unknown significance,\N,synonymous_variant,8.971,\N,\N,OPA1
611114,3:193385020:GA>G,NM_130837.2:c.2936del,NP_570850.2:p.Lys979ArgfsTer44,29/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,28.7,\N,\N,OPA1
611115,3:193385031:T>A,NM_130837.2:c.2945T>A,NP_570850.2:p.Leu982Ter,29/31,\N,Pathogenic,Optic atrophy 1,stop_gained,38,\N,\N,OPA1
611116,3:193385041:TAAACGCGT>AAAACACCG,NM_130837.2:c.2955_2963delinsAAAACACCG,NP_570850.2:p.Arg987_Val988delinsHisArg,29/31,\N,Pathogenic,Optic atrophy 1,missense_variant,23.2,\N,\N,OPA1
611117,3:193385045:C>T,NM_130837.2:c.2959C>T,NP_570850.2:p.Arg987Cys,29/31,\N,Pathogenic,Optic atrophy| acute & late onset,missense_variant,34,0.000226963,EVS_AA_AF,OPA1
611118,3:193385047:C>T,NM_130837.2:c.2961C>T,NP_570850.2:p.Arg987=,29/31,\N,Benign,\N,synonymous_variant,17.34,0.0265,1KG_AFR_AF,OPA1
611119,3:193385048:G>A,NM_130837.2:c.2962G>A,NP_570850.2:p.Val988Ile,29/31,\N,Pathogenic,Optic atrophy,missense_variant,29.7,0.000116279,EVS_EA_AF,OPA1
611120,3:193385051:C>T,NM_130837.2:c.2965C>T,NP_570850.2:p.Gln989Ter,29/31,\N,Pathogenic,Optic atrophy 1,stop_gained,50,\N,\N,OPA1
611121,3:193385052:A>G,NM_130837.2:c.2966A>G,NP_570850.2:p.Gln989Arg,29/31,\N,Unknown significance,\N,missense_variant,16.16,0.000347383,EXAC_EAS_AF,OPA1
611122,3:193385053:A>C,NM_130837.2:c.2967A>C,NP_570850.2:p.Gln989His,29/31,\N,Unknown significance,\N,missense_variant,22.7,0.000226963,EVS_AA_AF,OPA1
611123,3:193385059:G>A,NM_130837.2:c.2973G>A,NP_570850.2:p.Ala991=,29/31,\N,Benign,\N,synonymous_variant,12.29,0.124,1KG_EAS_AF,OPA1
611124,3:193385059:G>C,NM_130837.2:c.2973G>C,NP_570850.2:p.Ala991=,29/31,\N,Unknown significance,\N,synonymous_variant,10.19,0.000015205,EXAC_NFE_AF,OPA1
611125,3:193385064:AC>A,NM_130837.2:c.2980del,NP_570850.2:p.Leu994SerfsTer29,29/31,\N,Pathogenic,Optic atrophy,frameshift_variant,35,\N,\N,OPA1
611126,3:193385067:T>C,NM_130837.2:c.2981T>C,NP_570850.2:p.Leu994Pro,29/31,\N,Pathogenic,Optic atrophy 1,missense_variant&splice_region_variant,27.2,\N,\N,OPA1
611127,3:193385069:A>G,NM_130837.2:c.2983A>G,NP_570850.2:p.Lys995Glu,29/31,\N,Unknown significance,\N,missense_variant&splice_region_variant,21.9,0.000232992,EXAC_EAS_AF,OPA1
611128,3:193385070:G>T,NM_130837.2:c.2983+1G>T,\N,\N,29/30,Pathogenic,Optic atrophy 1,splice_donor_variant,23.1,\N,\N,OPA1
611129,3:193385071:T>C,NM_130837.2:c.2983+2T>C,\N,\N,29/30,Pathogenic,Optic atrophy 1,splice_donor_variant,23,\N,\N,OPA1
611130,3:193385074:G>A,NM_130837.2:c.2983+5G>A,\N,\N,29/30,Pathogenic,Optic atrophy 1,splice_region_variant&intron_variant,10.66,\N,\N,OPA1
611131,3:193385075:T>C,NM_130837.2:c.2983+6T>C,\N,\N,29/30,Pathogenic,Optic atrophy 1,splice_region_variant&intron_variant,6.898,\N,\N,OPA1
611132,3:193385076:A>G,NM_130837.2:c.2983+7A>G,\N,\N,29/30,Unknown significance,\N,splice_region_variant&intron_variant,3.968,0.0000617132,EXAC_SAS_AF,OPA1
611133,3:193385091:C>T,NM_130837.2:c.2983+22C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.961,0.0015,1KG_AFR_AF,OPA1
611134,3:193385092:T>C,NM_130837.2:c.2983+23T>C,\N,\N,29/30,Benign,\N,intron_variant,2.025,0.1248,1KG_AFR_AF,OPA1
611135,3:193385093:A>G,NM_130837.2:c.2983+24A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,5.87,0.000126518,EXAC_EAS_AF,OPA1
611136,3:193385095:C>T,NM_130837.2:c.2983+26C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.475,0.0000160741,EXAC_NFE_AF,OPA1
611137,3:193385096:T>C,NM_130837.2:c.2983+27T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.059,0.0000161363,EXAC_NFE_AF,OPA1
611138,3:193385100:T>TACCTTTCC,NM_130837.2:c.2983+40_2983+47dup,\N,\N,29/30,Unknown significance,\N,intron_variant,1.909,0.000416406,EXAC_AFR_AF,OPA1
611139,3:193385104:T>C,NM_130837.2:c.2983+35T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,4.953,0.0000169348,EXAC_NFE_AF,OPA1
611140,3:193385110:C>T,NM_130837.2:c.2983+41C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,3.667,0.0000947508,EXAC_AMR_AF,OPA1
611141,3:193385111:C>G,NM_130837.2:c.2983+42C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.444,0.000110132,EXAC_AFR_AF,OPA1
611142,3:193385117:C>T,NM_130837.2:c.2983+48C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,5.252,\N,\N,OPA1
611143,3:193385124:ATTTG>A,NM_130837.2:c.2983+62_2983+65del,\N,\N,29/30,Unknown significance,\N,intron_variant,6.419,\N,\N,OPA1
611144,3:193385139:C>T,NM_130837.2:c.2983+70C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,12.86,0.000023644,EXAC_NFE_AF,OPA1
611145,3:193385148:T>C,NM_130837.2:c.2983+79T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,11.78,0.001,1KG_SAS_AF,OPA1
611146,3:193385153:C>T,NM_130837.2:c.2983+84C>T,\N,\N,29/30,Benign,\N,intron_variant,4.717,0.0123,1KG_SAS_AF,OPA1
611147,3:193385157:C>G,NM_130837.2:c.2983+88C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.981,0.00033557,EXAC_EAS_AF,OPA1
611148,3:193385158:A>G,NM_130837.2:c.2983+89A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,4.54,\N,\N,OPA1
611149,3:193385159:G>T,NM_130837.2:c.2983+90G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.29,0.000189897,EXAC_AMR_AF,OPA1
611150,3:193385163:A>T,NM_130837.2:c.2983+94A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,3.556,0.001,1KG_EAS_AF,OPA1
611151,3:193385187:C>T,NM_130837.2:c.2983+118C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.296,0.000115154,EXAC_SAS_AF,OPA1
611152,3:193385188:G>A,NM_130837.2:c.2983+119G>A,\N,\N,29/30,Benign,\N,intron_variant,2.861,0.0523139,EXAC_EAS_AF,OPA1
611153,3:193385197:C>T,NM_130837.2:c.2983+128C>T,\N,\N,29/30,Benign,\N,intron_variant,1.901,0.0602022,EXAC_AFR_AF,OPA1
611154,3:193385198:G>A,NM_130837.2:c.2983+129G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.118,0.001,1KG_EUR_AF,OPA1
611155,3:193385214:C>T,NM_130837.2:c.2983+145C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,5.911,0.000120627,EXAC_NFE_AF,OPA1
611156,3:193385217:T>C,NM_130837.2:c.2983+148T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,5.476,0.0008,1KG_AFR_AF,OPA1
611157,3:193385220:G>A,NM_130837.2:c.2983+151G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,5.5,0.00167224,EXAC_EAS_AF,OPA1
611158,3:193385225:C>T,NM_130837.2:c.2983+156C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.466,\N,\N,OPA1
611159,3:193385233:G>A,NM_130837.2:c.2983+164G>A,\N,\N,29/30,Benign,\N,intron_variant,0.593,0.0420561,EXAC_OTH_AF,OPA1
611160,3:193385268:G>T,NM_130837.2:c.2983+199G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.999,\N,\N,OPA1
611161,3:193385271:AAC>A,NM_130837.2:c.2983+206_2983+207del,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611162,3:193385275:C>T,NM_130837.2:c.2983+206C>T,\N,\N,29/30,Benign,\N,intron_variant,0.997,0.599548,EXAC_FIN_AF,OPA1
611163,3:193385275:CA>TG,NM_130837.2:c.2983+206_2983+207inv,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611164,3:193385276:A>ATG,NM_130837.2:c.2983+207_2983+208insTG,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611165,3:193385276:A>G,NM_130837.2:c.2983+207A>G,\N,\N,29/30,Benign,\N,intron_variant,0.151,0.608491,EXAC_FIN_AF,OPA1
611166,3:193385278:TG>T,NM_130837.2:c.2983+210del,\N,\N,29/30,Unknown significance,\N,intron_variant,1.239,\N,\N,OPA1
611167,3:193385286:C>T,NM_130837.2:c.2983+217C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.038,\N,\N,OPA1
611168,3:193385321:G>A,NM_130837.2:c.2983+252G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.678,\N,\N,OPA1
611169,3:193385323:G>A,NM_130837.2:c.2983+254G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.665,0.001,1KG_EUR_AF,OPA1
611170,3:193385337:A>G,NM_130837.2:c.2983+268A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.161,0.001,1KG_EUR_AF,OPA1
611171,3:193385370:G>C,NM_130837.2:c.2983+301G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.514,0.0008,1KG_AFR_AF,OPA1
611172,3:193385384:C>T,NM_130837.2:c.2983+315C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.145,0.001,1KG_EUR_AF,OPA1
611173,3:193385387:G>A,NM_130837.2:c.2983+318G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.609,\N,\N,OPA1
611174,3:193385392:G>A,NM_130837.2:c.2983+323G>A,\N,\N,29/30,Benign,\N,intron_variant,0.569,0.0053,1KG_AFR_AF,OPA1
611175,3:193385407:C>T,NM_130837.2:c.2983+338C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.56,\N,\N,OPA1
611176,3:193385438:C>T,NM_130837.2:c.2983+369C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.066,0.0008,1KG_AFR_AF,OPA1
611177,3:193385447:G>A,NM_130837.2:c.2983+378G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.699,0.002,1KG_EUR_AF,OPA1
611178,3:193385453:C>T,NM_130837.2:c.2983+384C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,3.615,\N,\N,OPA1
611179,3:193385457:C>T,NM_130837.2:c.2983+388C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,4.133,\N,\N,OPA1
611180,3:193385459:C>A,NM_130837.2:c.2983+390C>A,\N,\N,29/30,Unknown significance,\N,intron_variant,6.586,\N,\N,OPA1
611181,3:193385459:C>CA,NM_130837.2:c.2983+411dup,\N,\N,29/30,Unknown significance,\N,intron_variant,6.511,\N,\N,OPA1
611182,3:193385484:A>C,NM_130837.2:c.2983+415A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.902,\N,\N,OPA1
611183,3:193385503:T>C,NM_130837.2:c.2983+434T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.19,\N,\N,OPA1
611184,3:193385565:A>G,NM_130837.2:c.2983+496A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.883,0.001,1KG_EAS_AF,OPA1
611185,3:193385587:C>T,NM_130837.2:c.2983+518C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,5.246,\N,\N,OPA1
611186,3:193385598:C>G,NM_130837.2:c.2983+529C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.763,0.0023,1KG_AFR_AF,OPA1
611187,3:193385599:G>A,NM_130837.2:c.2983+530G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.728,0.0029,1KG_AMR_AF,OPA1
611188,3:193385604:T>C,NM_130837.2:c.2983+535T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.236,0.003,1KG_EAS_AF,OPA1
611189,3:193385627:C>A,NM_130837.2:c.2983+558C>A,\N,\N,29/30,Unknown significance,\N,intron_variant,4.242,\N,\N,OPA1
611190,3:193385631:G>A,NM_130837.2:c.2983+562G>A,\N,\N,29/30,Benign,\N,intron_variant,1.935,0.0121,1KG_AFR_AF,OPA1
611191,3:193385650:C>A,NM_130837.2:c.2983+581C>A,\N,\N,29/30,Benign,\N,intron_variant,2.719,0.0265,1KG_AFR_AF,OPA1
611192,3:193385651:C>G,NM_130837.2:c.2983+582C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.358,0.0008,1KG_AFR_AF,OPA1
611193,3:193385652:G>A,NM_130837.2:c.2983+583G>A,\N,\N,29/30,Benign,\N,intron_variant,0.29,0.0082,1KG_SAS_AF,OPA1
611194,3:193385673:C>T,NM_130837.2:c.2983+604C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,4.128,\N,\N,OPA1
611195,3:193385692:G>A,NM_130837.2:c.2983+623G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,4.191,\N,\N,OPA1
611196,3:193385695:T>C,NM_130837.2:c.2983+626T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,3.423,0.0008,1KG_AFR_AF,OPA1
611197,3:193385703:T>C,NM_130837.2:c.2983+634T>C,\N,\N,29/30,Benign,\N,intron_variant,3.863,0.006,1KG_EAS_AF,OPA1
611198,3:193385706:C>G,NM_130837.2:c.2983+637C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.569,0.003,1KG_AFR_AF,OPA1
611199,3:193385818:T>A,NM_130837.2:c.2983+749T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,6.736,0.0029,1KG_AMR_AF,OPA1
611200,3:193385823:G>A,NM_130837.2:c.2983+754G>A,\N,\N,29/30,Benign,\N,intron_variant,2.762,0.0197,1KG_AFR_AF,OPA1
611201,3:193385844:G>A,NM_130837.2:c.2983+775G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,3.317,0.002,1KG_EUR_AF,OPA1
611202,3:193385885:A>G,NM_130837.2:c.2983+816A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.829,0.001,1KG_EUR_AF,OPA1
611203,3:193385891:A>G,NM_130837.2:c.2983+822A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.44,0.001,1KG_EAS_AF,OPA1
611204,3:193385912:T>C,NM_130837.2:c.2983+843T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,3.591,0.002,1KG_EUR_AF,OPA1
611205,3:193385919:A>T,NM_130837.2:c.2983+850A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.78,0.0015,1KG_AFR_AF,OPA1
611206,3:193385921:G>T,NM_130837.2:c.2983+852G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.224,\N,\N,OPA1
611207,3:193385928:C>T,NM_130837.2:c.2983+859C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,4.028,\N,\N,OPA1
611208,3:193385931:C>G,NM_130837.2:c.2983+862C>G,\N,\N,29/30,Benign,\N,intron_variant,3.496,0.0875,1KG_EUR_AF,OPA1
611209,3:193385965:G>A,NM_130837.2:c.2983+896G>A,\N,\N,29/30,Benign,\N,intron_variant,1.535,0.0179,1KG_EAS_AF,OPA1
611210,3:193386019:A>G,NM_130837.2:c.2983+950A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,4.067,\N,\N,OPA1
611211,3:193386025:C>T,NM_130837.2:c.2983+956C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.81,\N,\N,OPA1
611212,3:193386033:A>G,NM_130837.2:c.2983+964A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.647,\N,\N,OPA1
611213,3:193386061:A>G,NM_130837.2:c.2983+992A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.324,0.000382848,EXAC_SAS_AF,OPA1
611214,3:193386062:C>T,NM_130837.2:c.2983+993C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.028,0.0015,1KG_AFR_AF,OPA1
611215,3:193386063:G>A,NM_130837.2:c.2983+994G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.612,0.0031,1KG_SAS_AF,OPA1
611216,3:193386085:A>G,NM_130837.2:c.2983+1016A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.753,0.00035868,EXAC_NFE_AF,OPA1
611217,3:193386117:C>G,NM_130837.2:c.2983+1048C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.325,\N,\N,OPA1
611218,3:193386122:G>T,NM_130837.2:c.2983+1053G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.462,0.00322581,EXAC_AMR_AF,OPA1
611219,3:193386123:C>A,NM_130837.2:c.2983+1054C>A,\N,\N,29/30,Unknown significance,\N,intron_variant,5.625,0.000830565,EXAC_AFR_AF,OPA1
611220,3:193386133:A>G,NM_130837.2:c.2983+1064A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.625,0.0014,1KG_AMR_AF,OPA1
611221,3:193386159:C>T,NM_130837.2:c.2983+1090C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.452,0.00166113,EXAC_NFE_AF,OPA1
611222,3:193386160:G>A,NM_130837.2:c.2983+1091G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,3.164,\N,\N,OPA1
611223,3:193386163:G>A,NM_130837.2:c.2983+1094G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.031,0.000782677,EXAC_SAS_AF,OPA1
611224,3:193386166:C>T,NM_130837.2:c.2983+1097C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,4.171,\N,\N,OPA1
611225,3:193386173:T>C,NM_130837.2:c.2983+1104T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.117,0.001,1KG_EUR_AF,OPA1
611226,3:193386196:G>A,NM_130837.2:c.2983+1127G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.93,0.001,1KG_EUR_AF,OPA1
611227,3:193386210:G>A,NM_130837.2:c.2983+1141G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.506,\N,\N,OPA1
611228,3:193386211:T>C,NM_130837.2:c.2983+1142T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,4.074,0.000153752,EXAC_NFE_AF,OPA1
611229,3:193386227:G>A,NM_130837.2:c.2983+1158G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.848,0.00328947,EXAC_AMR_AF,OPA1
611230,3:193386233:G>A,NM_130837.2:c.2983+1164G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,3.088,0.000130446,EXAC_SAS_AF,OPA1
611231,3:193386235:G>A,NM_130837.2:c.2983+1166G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,4.626,0.000130446,EXAC_SAS_AF,OPA1
611232,3:193386238:C>T,NM_130837.2:c.2983+1169C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,4.701,\N,\N,OPA1
611233,3:193386239:C>T,NM_130837.2:c.2983+1170C>T,\N,\N,29/30,Benign,\N,intron_variant,5.219,0.585761,EXAC_AFR_AF,OPA1
611234,3:193386269:G>T,NM_130837.2:c.2983+1200G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.259,0.000846024,EXAC_AFR_AF,OPA1
611235,3:193386282:C>G,NM_130837.2:c.2983+1213C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.247,0.00380865,EXAC_NFE_AF,OPA1
611236,3:193386282:C>T,NM_130837.2:c.2983+1213C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,3.953,0.000260892,EXAC_SAS_AF,OPA1
611237,3:193386284:A>G,NM_130837.2:c.2983+1215A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.994,\N,\N,OPA1
611238,3:193386289:A>T,NM_130837.2:c.2983+1220A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,5.761,0.000130446,EXAC_SAS_AF,OPA1
611239,3:193386294:T>G,NM_130837.2:c.2983+1225T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,6.003,0.000151745,EXAC_NFE_AF,OPA1
611240,3:193386300:C>G,NM_130837.2:c.2983+1231C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.159,0.000150557,EXAC_NFE_AF,OPA1
611241,3:193386319:C>T,NM_130837.2:c.2983+1250C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,7.409,0.000130446,EXAC_SAS_AF,OPA1
611242,3:193386321:C>G,NM_130837.2:c.2983+1252C>G,\N,\N,29/30,Benign,\N,intron_variant,4.431,0.0547945,EXAC_AFR_AF,OPA1
611243,3:193386358:C>T,NM_130837.2:c.2983+1289C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,8.641,0.001,1KG_SAS_AF,OPA1
611244,3:193386370:A>C,NM_130837.2:c.2983+1301A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.971,\N,\N,OPA1
611245,3:193386379:A>C,NM_130837.2:c.2983+1310A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.749,\N,\N,OPA1
611246,3:193386381:C>A,NM_130837.2:c.2983+1312C>A,\N,\N,29/30,Unknown significance,\N,intron_variant,6.075,0.000133156,EXAC_SAS_AF,OPA1
611247,3:193386389:T>C,NM_130837.2:c.2983+1320T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.522,0.002,1KG_EAS_AF,OPA1
611248,3:193386395:G>A,NM_130837.2:c.2983+1326G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.637,\N,\N,OPA1
611249,3:193386395:G>C,NM_130837.2:c.2983+1326G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.087,\N,\N,OPA1
611250,3:193386401:C>T,NM_130837.2:c.2983+1332C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,3.364,0.0014,1KG_AMR_AF,OPA1
611251,3:193386402:T>C,NM_130837.2:c.2983+1333T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,5.466,0.000150105,EXAC_SAS_AF,OPA1
611252,3:193386416:C>T,NM_130837.2:c.2983+1347C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,7.034,0.0021645,EXAC_EAS_AF,OPA1
611253,3:193386421:G>C,NM_130837.2:c.2983+1352G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.056,\N,\N,OPA1
611254,3:193386429:A>ACTCTC,NM_130837.2:c.2983+1364_2983+1368dup,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611255,3:193386462:C>T,NM_130837.2:c.2983+1393C>T,\N,\N,29/30,Benign,\N,intron_variant,4.923,0.3221,1KG_SAS_AF,OPA1
611256,3:193386466:A>G,NM_130837.2:c.2983+1397A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.278,0.0015,1KG_AFR_AF,OPA1
611257,3:193386507:A>G,NM_130837.2:c.2983+1438A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.735,\N,\N,OPA1
611258,3:193386519:T>C,NM_130837.2:c.2983+1450T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.705,0.0014,1KG_AMR_AF,OPA1
611259,3:193386538:C>T,NM_130837.2:c.2983+1469C>T,\N,\N,29/30,Benign,\N,intron_variant,1.563,0.8364,1KG_SAS_AF,OPA1
611260,3:193386539:C>G,NM_130837.2:c.2983+1470C>G,\N,\N,29/30,Benign,\N,intron_variant,3.114,0.0072,1KG_SAS_AF,OPA1
611261,3:193386551:C>T,NM_130837.2:c.2983+1482C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,4.169,0.0023,1KG_AFR_AF,OPA1
611262,3:193386584:G>C,NM_130837.2:c.2983+1515G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.264,\N,\N,OPA1
611263,3:193386602:G>A,NM_130837.2:c.2983+1533G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,5.883,\N,\N,OPA1
611264,3:193386621:A>T,NM_130837.2:c.2983+1552A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.4,\N,\N,OPA1
611265,3:193386631:A>G,NM_130837.2:c.2983+1562A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.149,0.0014,1KG_AMR_AF,OPA1
611266,3:193386632:T>C,NM_130837.2:c.2983+1563T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.751,0.0031,1KG_SAS_AF,OPA1
611267,3:193386633:A>G,NM_130837.2:c.2983+1564A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.017,0.0008,1KG_AFR_AF,OPA1
611268,3:193386657:G>T,NM_130837.2:c.2983+1588G>T,\N,\N,29/30,Benign,\N,intron_variant,12.55,0.1499,1KG_AMR_AF,OPA1
611269,3:193386686:G>A,NM_130837.2:c.2983+1617G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.449,\N,\N,OPA1
611270,3:193386744:A>G,NM_130837.2:c.2983+1675A>G,\N,\N,29/30,Benign,\N,intron_variant,2.418,0.0121,1KG_AFR_AF,OPA1
611271,3:193386745:C>A,NM_130837.2:c.2983+1676C>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.317,\N,\N,OPA1
611272,3:193386765:T>C,NM_130837.2:c.2983+1696T>C,\N,\N,29/30,Benign,\N,intron_variant,3.469,0.1369,1KG_AFR_AF,OPA1
611273,3:193386768:G>A,NM_130837.2:c.2983+1699G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.558,0.002,1KG_SAS_AF,OPA1
611274,3:193386781:T>C,NM_130837.2:c.2983+1712T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.457,0.0014,1KG_AMR_AF,OPA1
611275,3:193386796:G>A,NM_130837.2:c.2983+1727G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.483,\N,\N,OPA1
611276,3:193386827:C>A,NM_130837.2:c.2983+1758C>A,\N,\N,29/30,Unknown significance,\N,intron_variant,5.824,\N,\N,OPA1
611277,3:193386833:T>C,NM_130837.2:c.2983+1764T>C,\N,\N,29/30,Benign,\N,intron_variant,1.524,0.41,1KG_SAS_AF,OPA1
611278,3:193386837:A>G,NM_130837.2:c.2983+1768A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.96,\N,\N,OPA1
611279,3:193386884:A>G,NM_130837.2:c.2983+1815A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,4.685,\N,\N,OPA1
611280,3:193386897:C>T,NM_130837.2:c.2983+1828C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,4.809,0.002,1KG_SAS_AF,OPA1
611281,3:193386953:C>G,NM_130837.2:c.2983+1884C>G,\N,\N,29/30,Benign,\N,intron_variant,0.363,0.013,1KG_AMR_AF,OPA1
611282,3:193386989:C>T,NM_130837.2:c.2983+1920C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.095,0.0008,1KG_AFR_AF,OPA1
611283,3:193386990:G>A,NM_130837.2:c.2983+1921G>A,\N,\N,29/30,Benign,\N,intron_variant,2.08,0.0484,1KG_AFR_AF,OPA1
611284,3:193387023:G>A,NM_130837.2:c.2983+1954G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.369,0.001,1KG_EAS_AF,OPA1
611285,3:193387040:C>G,NM_130837.2:c.2983+1971C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.711,0.0014,1KG_AMR_AF,OPA1
611286,3:193387046:A>G,NM_130837.2:c.2983+1977A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.493,\N,\N,OPA1
611287,3:193387110:G>A,NM_130837.2:c.2983+2041G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.071,0.0023,1KG_AFR_AF,OPA1
611288,3:193387114:C>T,NM_130837.2:c.2983+2045C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,3.488,0.0008,1KG_AFR_AF,OPA1
611289,3:193387117:A>G,NM_130837.2:c.2983+2048A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.748,0.001,1KG_EAS_AF,OPA1
611290,3:193387172:C>A,NM_130837.2:c.2983+2103C>A,\N,\N,29/30,Unknown significance,\N,intron_variant,6.816,0.001,1KG_EUR_AF,OPA1
611291,3:193387176:G>A,NM_130837.2:c.2983+2107G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,5.18,\N,\N,OPA1
611292,3:193387233:A>AT,NM_130837.2:c.2983+2167dup,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611293,3:193387237:A>G,NM_130837.2:c.2983+2168A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,8.288,0.001,1KG_EAS_AF,OPA1
611294,3:193387257:C>T,NM_130837.2:c.2983+2188C>T,\N,\N,29/30,Benign,\N,intron_variant,1.623,0.0123,1KG_SAS_AF,OPA1
611295,3:193387258:G>A,NM_130837.2:c.2983+2189G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.448,\N,\N,OPA1
611296,3:193387263:G>A,NM_130837.2:c.2983+2194G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,6.341,0.0031,1KG_SAS_AF,OPA1
611297,3:193387327:A>G,NM_130837.2:c.2983+2258A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.299,\N,\N,OPA1
611298,3:193387345:G>A,NM_130837.2:c.2983+2276G>A,\N,\N,29/30,Benign,\N,intron_variant,0.516,0.4264,1KG_EUR_AF,OPA1
611299,3:193387393:C>T,NM_130837.2:c.2983+2324C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.002,\N,\N,OPA1
611300,3:193387394:G>A,NM_130837.2:c.2983+2325G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.234,0.001,1KG_SAS_AF,OPA1
611301,3:193387427:A>T,NM_130837.2:c.2983+2358A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,7.536,0.0008,1KG_AFR_AF,OPA1
611302,3:193387429:A>T,NM_130837.2:c.2983+2360A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,8.053,\N,\N,OPA1
611303,3:193387480:A>G,NM_130837.2:c.2983+2411A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.251,\N,\N,OPA1
611304,3:193387522:T>C,NM_130837.2:c.2983+2453T>C,\N,\N,29/30,Benign,\N,intron_variant,8.708,0.0159,1KG_EUR_AF,OPA1
611305,3:193387549:T>C,NM_130837.2:c.2983+2480T>C,\N,\N,29/30,Benign,\N,intron_variant,3.721,0.0358,1KG_EUR_AF,OPA1
611306,3:193387557:G>A,NM_130837.2:c.2983+2488G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.571,\N,\N,OPA1
611307,3:193387574:C>G,NM_130837.2:c.2983+2505C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.232,\N,\N,OPA1
611308,3:193387585:C>G,NM_130837.2:c.2983+2516C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.388,0.001,1KG_EUR_AF,OPA1
611309,3:193387585:C>T,NM_130837.2:c.2983+2516C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.934,\N,\N,OPA1
611310,3:193387601:A>G,NM_130837.2:c.2983+2532A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,5.156,0,1KG_ALL_AF|1KG_AFR_AF|1KG_AMR_AF|1KG_EAS_AF|1KG_EUR_AF|1KG_SAS_AF,OPA1
611311,3:193387621:T>C,NM_130837.2:c.2983+2552T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,3.758,0.0014,1KG_AMR_AF,OPA1
611312,3:193387622:A>C,NM_130837.2:c.2983+2553A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.317,\N,\N,OPA1
611313,3:193387630:T>C,NM_130837.2:c.2983+2561T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,3.622,0.001,1KG_SAS_AF,OPA1
611314,3:193387698:C>T,NM_130837.2:c.2983+2629C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,3.693,\N,\N,OPA1
611315,3:193387768:G>A,NM_130837.2:c.2983+2699G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,5.39,0.001,1KG_EUR_AF,OPA1
611316,3:193387786:G>C,NM_130837.2:c.2983+2717G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.948,0.0015,1KG_AFR_AF,OPA1
611317,3:193387792:C>G,NM_130837.2:c.2983+2723C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.222,0.001,1KG_EAS_AF,OPA1
611318,3:193387831:T>C,NM_130837.2:c.2983+2762T>C,\N,\N,29/30,Benign,\N,intron_variant,3.015,0.5862,1KG_AFR_AF,OPA1
611319,3:193387870:C>T,NM_130837.2:c.2983+2801C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.506,\N,\N,OPA1
611320,3:193387881:A>T,NM_130837.2:c.2983+2812A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.308,0.0008,1KG_AFR_AF,OPA1
611321,3:193387894:C>T,NM_130837.2:c.2983+2825C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,8.392,0.001,1KG_EAS_AF,OPA1
611322,3:193387937:C>A,NM_130837.2:c.2983+2868C>A,\N,\N,29/30,Benign,\N,intron_variant,3.461,0.5855,1KG_AFR_AF,OPA1
611323,3:193388054:A>G,NM_130837.2:c.2983+2985A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.763,0.002,1KG_EAS_AF,OPA1
611324,3:193388061:C>T,NM_130837.2:c.2983+2992C>T,\N,\N,29/30,Benign,\N,intron_variant,3.754,0.0265,1KG_AFR_AF,OPA1
611325,3:193388072:A>G,NM_130837.2:c.2983+3003A>G,\N,\N,29/30,Benign,\N,intron_variant,1.947,0.0092,1KG_SAS_AF,OPA1
611326,3:193388078:T>C,NM_130837.2:c.2983+3009T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.858,\N,\N,OPA1
611327,3:193388084:A>G,NM_130837.2:c.2983+3015A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.126,0.001,1KG_EUR_AF,OPA1
611328,3:193388097:G>A,NM_130837.2:c.2983+3028G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,3.055,0.001,1KG_EAS_AF,OPA1
611329,3:193388122:T>C,NM_130837.2:c.2983+3053T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,8.894,\N,\N,OPA1
611330,3:193388163:G>T,NM_130837.2:c.2983+3094G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.434,0.001,1KG_SAS_AF,OPA1
611331,3:193388165:CT>C,NM_130837.2:c.2983+3098del,\N,\N,29/30,Unknown significance,\N,intron_variant,4.168,0.0029,1KG_AMR_AF,OPA1
611332,3:193388174:C>A,NM_130837.2:c.2983+3105C>A,\N,\N,29/30,Benign,\N,intron_variant,0.515,0.0477,1KG_AFR_AF,OPA1
611333,3:193388175:A>C,NM_130837.2:c.2983+3106A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.822,\N,\N,OPA1
611334,3:193388177:C>CT,NM_130837.2:c.2983+3123dup,\N,\N,29/30,Unknown significance,\N,intron_variant,3.013,\N,\N,OPA1
611335,3:193388177:CT>C,NM_130837.2:c.2983+3123del,\N,\N,29/30,Unknown significance,\N,intron_variant,0.777,\N,\N,OPA1
611336,3:193388198:G>A,NM_130837.2:c.2983+3129G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.516,0.0014,1KG_AMR_AF,OPA1
611337,3:193388211:G>A,NM_130837.2:c.2983+3142G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.572,0.0045,1KG_AFR_AF,OPA1
611338,3:193388237:C>T,NM_130837.2:c.2983+3168C>T,\N,\N,29/30,Benign,\N,intron_variant,1.714,0.584,1KG_AFR_AF,OPA1
611339,3:193388258:T>G,NM_130837.2:c.2983+3189T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.332,\N,\N,OPA1
611340,3:193388281:G>A,NM_130837.2:c.2983+3212G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.307,\N,\N,OPA1
611341,3:193388292:G>A,NM_130837.2:c.2983+3223G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.447,\N,\N,OPA1
611342,3:193388300:C>T,NM_130837.2:c.2983+3231C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.202,\N,\N,OPA1
611343,3:193388345:C>T,NM_130837.2:c.2983+3276C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.526,\N,\N,OPA1
611344,3:193388348:G>C,NM_130837.2:c.2983+3279G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.313,0.003,1KG_EAS_AF,OPA1
611345,3:193388354:C>A,NM_130837.2:c.2983+3285C>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.385,\N,\N,OPA1
611346,3:193388397:C>T,NM_130837.2:c.2983+3328C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.591,0.001,1KG_EUR_AF,OPA1
611347,3:193388398:G>A,NM_130837.2:c.2983+3329G>A,\N,\N,29/30,Benign,\N,intron_variant,0.253,0.0144,1KG_AFR_AF,OPA1
611348,3:193388416:A>G,NM_130837.2:c.2983+3347A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.68,\N,\N,OPA1
611349,3:193388433:G>A,NM_130837.2:c.2983+3364G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.73,0.001,1KG_SAS_AF,OPA1
611350,3:193388488:A>G,NM_130837.2:c.2983+3419A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,7.416,0.0014,1KG_AMR_AF,OPA1
611351,3:193388521:A>G,NM_130837.2:c.2983+3452A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.192,\N,\N,OPA1
611352,3:193388523:A>C,NM_130837.2:c.2983+3454A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.149,0.0015,1KG_AFR_AF,OPA1
611353,3:193388524:T>C,NM_130837.2:c.2983+3455T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.676,\N,\N,OPA1
611354,3:193388581:T>C,NM_130837.2:c.2983+3512T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.357,0.002,1KG_SAS_AF,OPA1
611355,3:193388607:C>T,NM_130837.2:c.2983+3538C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,9.553,\N,\N,OPA1
611356,3:193388610:A>G,NM_130837.2:c.2983+3541A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,9.652,0.001,1KG_EAS_AF,OPA1
611357,3:193388619:T>C,NM_130837.2:c.2983+3550T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,7.636,\N,\N,OPA1
611358,3:193388620:C>T,NM_130837.2:c.2983+3551C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,5.085,\N,\N,OPA1
611359,3:193388625:A>G,NM_130837.2:c.2983+3556A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,5.85,\N,\N,OPA1
611360,3:193388642:T>C,NM_130837.2:c.2983+3573T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.218,\N,\N,OPA1
611361,3:193388650:T>A,NM_130837.2:c.2983+3581T>A,\N,\N,29/30,Benign,\N,intron_variant,6.828,0.0265,1KG_AFR_AF,OPA1
611362,3:193388659:G>A,NM_130837.2:c.2983+3590G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,4.862,\N,\N,OPA1
611363,3:193388667:G>GA,NM_130837.2:c.2983+3601dup,\N,\N,29/30,Benign,\N,intron_variant,0.733,0.0265,1KG_AFR_AF,OPA1
611364,3:193388673:A>AC,NM_130837.2:c.2983+3605dup,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611365,3:193388734:A>T,NM_130837.2:c.2983+3665A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,5.627,0.001,1KG_EAS_AF,OPA1
611366,3:193388808:C>T,NM_130837.2:c.2983+3739C>T,\N,\N,29/30,Benign,\N,intron_variant,5.71,0.0053,1KG_AFR_AF,OPA1
611367,3:193388813:A>G,NM_130837.2:c.2983+3744A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,4.864,\N,\N,OPA1
611368,3:193388819:T>C,NM_130837.2:c.2983+3750T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,3.387,\N,\N,OPA1
611369,3:193388824:C>T,NM_130837.2:c.2983+3755C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,3.64,\N,\N,OPA1
611370,3:193388825:T>G,NM_130837.2:c.2983+3756T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,4.939,\N,\N,OPA1
611371,3:193388826:C>A,NM_130837.2:c.2983+3757C>A,\N,\N,29/30,Unknown significance,\N,intron_variant,5.196,\N,\N,OPA1
611372,3:193388832:A>G,NM_130837.2:c.2983+3763A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.361,\N,\N,OPA1
611373,3:193388913:C>G,NM_130837.2:c.2983+3844C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.387,0.001,1KG_EAS_AF,OPA1
611374,3:193388923:G>A,NM_130837.2:c.2983+3854G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.021,0.001,1KG_EAS_AF|1KG_SAS_AF,OPA1
611375,3:193388955:G>A,NM_130837.2:c.2983+3886G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,9.756,0.0008,1KG_AFR_AF,OPA1
611376,3:193388965:A>G,NM_130837.2:c.2983+3896A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,13.31,\N,\N,OPA1
611377,3:193389053:G>A,NM_130837.2:c.2983+3984G>A,\N,\N,29/30,Benign,\N,intron_variant,2.583,0.062,1KG_AFR_AF,OPA1
611378,3:193389091:C>G,NM_130837.2:c.2983+4022C>G,\N,\N,29/30,Benign,\N,intron_variant,1.335,0.0189,1KG_AFR_AF,OPA1
611379,3:193389101:A>G,NM_130837.2:c.2983+4032A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.959,0.0038,1KG_AFR_AF,OPA1
611380,3:193389106:G>T,NM_130837.2:c.2983+4037G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.568,0.001,1KG_SAS_AF,OPA1
611381,3:193389127:A>G,NM_130837.2:c.2983+4058A>G,\N,\N,29/30,Benign,\N,intron_variant,3.64,0.0367,1KG_EAS_AF,OPA1
611382,3:193389128:A>G,NM_130837.2:c.2983+4059A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.995,0.0029,1KG_AMR_AF,OPA1
611383,3:193389151:T>G,NM_130837.2:c.2983+4082T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,5.645,\N,\N,OPA1
611384,3:193389152:T>A,NM_130837.2:c.2983+4083T>A,\N,\N,29/30,Benign,\N,intron_variant,5.206,0.0101,1KG_AMR_AF,OPA1
611385,3:193389171:TAAC>T,NM_130837.2:c.2983+4103_2983+4105del,\N,\N,29/30,Benign,\N,intron_variant,7.795,0.0367,1KG_EAS_AF,OPA1
611386,3:193389214:A>G,NM_130837.2:c.2983+4145A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.337,\N,\N,OPA1
611387,3:193389243:G>A,NM_130837.2:c.2983+4174G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.898,0.0015,1KG_AFR_AF,OPA1
611388,3:193389246:G>C,NM_130837.2:c.2983+4177G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.039,\N,\N,OPA1
611389,3:193389252:TAAAAC>T,NM_130837.2:c.2983+4184_2983+4188del,\N,\N,29/30,Unknown significance,\N,intron_variant,5.947,\N,\N,OPA1
611390,3:193389266:A>G,NM_130837.2:c.2983+4197A>G,\N,\N,29/30,Benign,\N,intron_variant,1.159,0.0197,1KG_AFR_AF,OPA1
611391,3:193389278:A>G,NM_130837.2:c.2983+4209A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.973,0.0008,1KG_AFR_AF,OPA1
611392,3:193389284:G>T,NM_130837.2:c.2983+4215G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.195,0.0023,1KG_AFR_AF,OPA1
611393,3:193389305:T>A,NM_130837.2:c.2983+4236T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,4.556,\N,\N,OPA1
611394,3:193389308:A>AT,NM_130837.2:c.2983+4240dup,\N,\N,29/30,Benign,\N,intron_variant,0.414,0.0238,1KG_EAS_AF,OPA1
611395,3:193389324:T>A,NM_130837.2:c.2983+4255T>A,\N,\N,29/30,Benign,\N,intron_variant,5.559,0.587,1KG_AFR_AF,OPA1
611396,3:193389329:G>T,NM_130837.2:c.2983+4260G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.611,\N,\N,OPA1
611397,3:193389333:G>T,NM_130837.2:c.2983+4264G>T,\N,\N,29/30,Benign,\N,intron_variant,1.778,0.0072,1KG_AMR_AF,OPA1
611398,3:193389340:G>A,NM_130837.2:c.2983+4271G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.381,\N,\N,OPA1
611399,3:193389352:G>A,NM_130837.2:c.2983+4283G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.08,\N,\N,OPA1
611400,3:193389355:G>A,NM_130837.2:c.2983+4286G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.679,0.001,1KG_EUR_AF,OPA1
611401,3:193389360:A>AT,NM_130837.2:c.2983+4292dup,\N,\N,29/30,Benign,\N,intron_variant,0.063,0.0367,1KG_EAS_AF,OPA1
611402,3:193389368:G>A,NM_130837.2:c.2983+4299G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,5.067,0.0031,1KG_SAS_AF,OPA1
611403,3:193389378:A>G,NM_130837.2:c.2983+4309A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,6.161,0.001,1KG_EAS_AF,OPA1
611404,3:193389390:G>A,NM_130837.2:c.2983+4321G>A,\N,\N,29/30,Benign,\N,intron_variant,6.687,0.5855,1KG_AFR_AF,OPA1
611405,3:193389413:C>A,NM_130837.2:c.2983+4344C>A,\N,\N,29/30,Benign,\N,intron_variant,2.355,0.4254,1KG_EUR_AF,OPA1
611406,3:193389427:G>A,NM_130837.2:c.2983+4358G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.399,0.002,1KG_EAS_AF,OPA1
611407,3:193389428:A>T,NM_130837.2:c.2983+4359A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.644,0.0041,1KG_SAS_AF,OPA1
611408,3:193389463:G>A,NM_130837.2:c.2983+4394G>A,\N,\N,29/30,Benign,\N,intron_variant,3.365,0.3411,1KG_AFR_AF,OPA1
611409,3:193389470:A>T,NM_130837.2:c.2983+4401A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.293,\N,\N,OPA1
611410,3:193389485:G>A,NM_130837.2:c.2983+4416G>A,\N,\N,29/30,Benign,\N,intron_variant,8.232,0.6188,1KG_AFR_AF,OPA1
611411,3:193389491:T>C,NM_130837.2:c.2983+4422T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.224,0.0008,1KG_AFR_AF,OPA1
611412,3:193389502:G>A,NM_130837.2:c.2983+4433G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,4.73,0.0023,1KG_AFR_AF,OPA1
611413,3:193389505:G>A,NM_130837.2:c.2983+4436G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.275,0.0008,1KG_AFR_AF,OPA1
611414,3:193389536:T>C,NM_130837.2:c.2983+4467T>C,\N,\N,29/30,Benign,\N,intron_variant,1.54,0.005,1KG_EAS_AF,OPA1
611415,3:193389544:T>G,NM_130837.2:c.2983+4475T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,5.238,\N,\N,OPA1
611416,3:193389558:A>G,NM_130837.2:c.2983+4489A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.595,0.0008,1KG_AFR_AF,OPA1
611417,3:193389559:A>T,NM_130837.2:c.2983+4490A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.6,0.0008,1KG_AFR_AF,OPA1
611418,3:193389576:T>C,NM_130837.2:c.2983+4507T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,3.335,0.0008,1KG_AFR_AF,OPA1
611419,3:193389604:G>T,NM_130837.2:c.2983+4535G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,3.032,\N,\N,OPA1
611420,3:193389622:A>G,NM_130837.2:c.2983+4553A>G,\N,\N,29/30,Benign,\N,intron_variant,3.804,0.0356,1KG_AFR_AF,OPA1
611421,3:193389639:A>G,NM_130837.2:c.2983+4570A>G,\N,\N,29/30,Benign,\N,intron_variant,3.915,0.0212,1KG_AFR_AF,OPA1
611422,3:193389655:T>C,NM_130837.2:c.2983+4586T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,3.353,\N,\N,OPA1
611423,3:193389672:C>T,NM_130837.2:c.2983+4603C>T,\N,\N,29/30,Benign,\N,intron_variant,2.857,0.0179,1KG_EAS_AF,OPA1
611424,3:193389685:T>C,NM_130837.2:c.2983+4616T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.221,\N,\N,OPA1
611425,3:193389687:A>G,NM_130837.2:c.2983+4618A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.371,\N,\N,OPA1
611426,3:193389691:GA>G,NM_130837.2:c.2983+4623del,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611427,3:193389692:A>G,NM_130837.2:c.2983+4623A>G,\N,\N,29/30,Benign,\N,intron_variant,1.436,0.7617,1KG_AFR_AF,OPA1
611428,3:193389731:G>A,NM_130837.2:c.2983+4662G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.255,0.001,1KG_EAS_AF,OPA1
611429,3:193389740:C>G,NM_130837.2:c.2983+4671C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.863,\N,\N,OPA1
611430,3:193389758:G>T,NM_130837.2:c.2983+4689G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.601,0.001,1KG_EUR_AF,OPA1
611431,3:193389763:A>G,NM_130837.2:c.2983+4694A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.71,0.0029,1KG_AMR_AF,OPA1
611432,3:193389765:A>T,NM_130837.2:c.2983+4696A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,5.628,\N,\N,OPA1
611433,3:193389786:A>G,NM_130837.2:c.2983+4717A>G,\N,\N,29/30,Benign,\N,intron_variant,7.958,0.0053,1KG_AFR_AF,OPA1
611434,3:193389832:T>C,NM_130837.2:c.2983+4763T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,9.137,\N,\N,OPA1
611435,3:193389883:T>TC,NM_130837.2:c.2983+4817dup,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611436,3:193389900:G>A,NM_130837.2:c.2983+4831G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.954,\N,\N,OPA1
611437,3:193389912:A>G,NM_130837.2:c.2983+4843A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,4.219,0.002,1KG_EAS_AF,OPA1
611438,3:193389940:G>T,NM_130837.2:c.2983+4871G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.054,0.0031,1KG_SAS_AF,OPA1
611439,3:193389969:G>A,NM_130837.2:c.2983+4900G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.303,\N,\N,OPA1
611440,3:193389986:T>G,NM_130837.2:c.2983+4917T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,11.24,0.001,1KG_EAS_AF,OPA1
611441,3:193390034:A>G,NM_130837.2:c.2983+4965A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.712,0.0008,1KG_AFR_AF,OPA1
611442,3:193390091:C>A,NM_130837.2:c.2983+5022C>A,\N,\N,29/30,Unknown significance,\N,intron_variant,12.98,0.001,1KG_SAS_AF,OPA1
611443,3:193390143:A>G,NM_130837.2:c.2983+5074A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.119,0.0029,1KG_AMR_AF,OPA1
611444,3:193390176:G>A,NM_130837.2:c.2983+5107G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.207,0.001,1KG_SAS_AF,OPA1
611445,3:193390215:T>A,NM_130837.2:c.2983+5146T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,4.252,\N,\N,OPA1
611446,3:193390242:T>C,NM_130837.2:c.2983+5173T>C,\N,\N,29/30,Benign,\N,intron_variant,2.357,0.1369,1KG_AFR_AF,OPA1
611447,3:193390261:A>T,NM_130837.2:c.2983+5192A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,4.93,0.0008,1KG_AFR_AF,OPA1
611448,3:193390275:C>A,NM_130837.2:c.2983+5206C>A,\N,\N,29/30,Benign,\N,intron_variant,0.416,0.0507,1KG_AFR_AF,OPA1
611449,3:193390294:G>A,NM_130837.2:c.2983+5225G>A,\N,\N,29/30,Benign,\N,intron_variant,0.898,0.0779,1KG_AFR_AF,OPA1
611450,3:193390304:A>C,NM_130837.2:c.2983+5235A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.429,0.002,1KG_EUR_AF,OPA1
611451,3:193390314:A>T,NM_130837.2:c.2983+5245A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.531,\N,\N,OPA1
611452,3:193390357:C>G,NM_130837.2:c.2983+5288C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.94,\N,\N,OPA1
611453,3:193390364:C>T,NM_130837.2:c.2983+5295C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,4.165,\N,\N,OPA1
611454,3:193390370:A>C,NM_130837.2:c.2983+5301A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.07,\N,\N,OPA1
611455,3:193390379:C>T,NM_130837.2:c.2983+5310C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.671,0.0031,1KG_SAS_AF,OPA1
611456,3:193390380:G>A,NM_130837.2:c.2983+5311G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.078,\N,\N,OPA1
611457,3:193390386:G>A,NM_130837.2:c.2983+5317G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.496,\N,\N,OPA1
611458,3:193390389:G>A,NM_130837.2:c.2983+5320G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.315,\N,\N,OPA1
611459,3:193390395:C>T,NM_130837.2:c.2983+5326C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.509,\N,\N,OPA1
611460,3:193390396:G>A,NM_130837.2:c.2983+5327G>A,\N,\N,29/30,Benign,\N,intron_variant,2.533,0.0367,1KG_EAS_AF,OPA1
611461,3:193390396:G>C,NM_130837.2:c.2983+5327G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.307,\N,\N,OPA1
611462,3:193390398:C>T,NM_130837.2:c.2983+5329C>T,\N,\N,29/30,Benign,\N,intron_variant,1.007,0.062,1KG_AFR_AF,OPA1
611463,3:193390420:G>C,NM_130837.2:c.2983+5351G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.22,\N,\N,OPA1
611464,3:193390438:A>G,NM_130837.2:c.2983+5369A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.388,\N,\N,OPA1
611465,3:193390486:C>T,NM_130837.2:c.2983+5417C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.429,0.001,1KG_EAS_AF,OPA1
611466,3:193390487:G>A,NM_130837.2:c.2983+5418G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.044,0.001,1KG_EAS_AF,OPA1
611467,3:193390522:G>A,NM_130837.2:c.2983+5453G>A,\N,\N,29/30,Benign,\N,intron_variant,0.335,0.2376,1KG_EUR_AF,OPA1
611468,3:193390551:G>A,NM_130837.2:c.2983+5482G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.25,0.0014,1KG_AMR_AF,OPA1
611469,3:193390562:A>G,NM_130837.2:c.2983+5493A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.499,\N,\N,OPA1
611470,3:193390572:C>T,NM_130837.2:c.2983+5503C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.709,\N,\N,OPA1
611471,3:193390580:C>A,NM_130837.2:c.2983+5511C>A,\N,\N,29/30,Unknown significance,\N,intron_variant,3.152,0.002,1KG_SAS_AF,OPA1
611472,3:193390583:G>A,NM_130837.2:c.2983+5514G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.381,\N,\N,OPA1
611473,3:193390593:G>A,NM_130837.2:c.2983+5524G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.987,0.001,1KG_EAS_AF,OPA1
611474,3:193390645:G>A,NM_130837.2:c.2983+5576G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.026,\N,\N,OPA1
611475,3:193390657:CA>C,NM_130837.2:c.2983+5604del,\N,\N,29/30,Unknown significance,\N,intron_variant,3.935,\N,\N,OPA1
611476,3:193390696:T>A,NM_130837.2:c.2983+5627T>A,\N,\N,29/30,Benign,\N,intron_variant,6.086,0.0091,1KG_AFR_AF,OPA1
611477,3:193390758:T>A,NM_130837.2:c.2983+5689T>A,\N,\N,29/30,Benign,\N,intron_variant,6.405,0.4304,1KG_AFR_AF,OPA1
611478,3:193390775:T>C,NM_130837.2:c.2983+5706T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.45,0.001,1KG_SAS_AF,OPA1
611479,3:193390790:G>A,NM_130837.2:c.2983+5721G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.566,0.001,1KG_SAS_AF,OPA1
611480,3:193390854:G>A,NM_130837.2:c.2983+5785G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.803,0.001,1KG_SAS_AF,OPA1
611481,3:193390887:G>A,NM_130837.2:c.2983+5818G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.402,0.001,1KG_EAS_AF,OPA1
611482,3:193390902:G>A,NM_130837.2:c.2983+5833G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.269,0.0023,1KG_AFR_AF,OPA1
611483,3:193390916:C>G,NM_130837.2:c.2983+5847C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.91,0.002,1KG_EUR_AF,OPA1
611484,3:193390917:T>C,NM_130837.2:c.2983+5848T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,3.616,0.0029,1KG_AMR_AF,OPA1
611485,3:193390930:T>C,NM_130837.2:c.2983+5861T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,3.098,\N,\N,OPA1
611486,3:193390938:G>A,NM_130837.2:c.2983+5869G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.857,0.001,1KG_EUR_AF,OPA1
611487,3:193390959:G>A,NM_130837.2:c.2983+5890G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.844,\N,\N,OPA1
611488,3:193390989:C>T,NM_130837.2:c.2983+5920C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.373,\N,\N,OPA1
611489,3:193391000:T>C,NM_130837.2:c.2983+5931T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,3.274,0.002,1KG_SAS_AF,OPA1
611490,3:193391005:T>C,NM_130837.2:c.2983+5936T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,4.877,\N,\N,OPA1
611491,3:193391085:G>A,NM_130837.2:c.2983+6016G>A,\N,\N,29/30,Benign,\N,intron_variant,4.129,0.6188,1KG_AFR_AF,OPA1
611492,3:193391092:A>G,NM_130837.2:c.2983+6023A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,4.115,0.002,1KG_EUR_AF,OPA1
611493,3:193391160:T>C,NM_130837.2:c.2983+6091T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.174,\N,\N,OPA1
611494,3:193391201:A>G,NM_130837.2:c.2983+6132A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,6.006,\N,\N,OPA1
611495,3:193391307:A>G,NM_130837.2:c.2983+6238A>G,\N,\N,29/30,Benign,\N,intron_variant,4.591,0.0377,1KG_EAS_AF,OPA1
611496,3:193391328:T>G,NM_130837.2:c.2983+6259T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,4.771,\N,\N,OPA1
611497,3:193391332:A>G,NM_130837.2:c.2983+6263A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.408,0.0008,1KG_AFR_AF,OPA1
611498,3:193391341:A>G,NM_130837.2:c.2983+6272A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.591,0.0008,1KG_AFR_AF,OPA1
611499,3:193391342:T>A,NM_130837.2:c.2983+6273T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,6.95,\N,\N,OPA1
611500,3:193391384:C>T,NM_130837.2:c.2983+6315C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,4.098,0.001,1KG_EAS_AF,OPA1
611501,3:193391384:CAG>C,NM_130837.2:c.2983+6317_2983+6318del,\N,\N,29/30,Benign,\N,intron_variant,7.357,0.0129,1KG_EUR_AF,OPA1
611502,3:193391389:A>G,NM_130837.2:c.2983+6320A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.306,0.001,1KG_EUR_AF,OPA1
611503,3:193391403:T>G,NM_130837.2:c.2983+6334T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.557,0.001,1KG_SAS_AF,OPA1
611504,3:193391428:G>A,NM_130837.2:c.2983+6359G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.012,0.0008,1KG_AFR_AF,OPA1
611505,3:193391429:G>A,NM_130837.2:c.2983+6360G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.614,\N,\N,OPA1
611506,3:193391496:A>G,NM_130837.2:c.2983+6427A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.316,0.0008,1KG_AFR_AF,OPA1
611507,3:193391509:C>T,NM_130837.2:c.2983+6440C>T,\N,\N,29/30,Benign,\N,intron_variant,0.871,0.0333,1KG_AFR_AF,OPA1
611508,3:193391552:C>A,NM_130837.2:c.2983+6483C>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.298,\N,\N,OPA1
611509,3:193391651:A>G,NM_130837.2:c.2983+6582A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,10.98,\N,\N,OPA1
611510,3:193391680:A>G,NM_130837.2:c.2983+6611A>G,\N,\N,29/30,Benign,\N,intron_variant,2.172,0.5855,1KG_AFR_AF,OPA1
611511,3:193391741:A>T,NM_130837.2:c.2983+6672A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.065,\N,\N,OPA1
611512,3:193391768:A>C,NM_130837.2:c.2983+6699A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,19.63,0.001,1KG_EUR_AF,OPA1
611513,3:193391772:G>C,NM_130837.2:c.2983+6703G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,17.48,0.0008,1KG_AFR_AF,OPA1
611514,3:193391792:T>C,NM_130837.2:c.2983+6723T>C,\N,\N,29/30,Benign,\N,intron_variant,17.71,0.0377,1KG_EAS_AF,OPA1
611515,3:193391803:C>T,NM_130837.2:c.2983+6734C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,12.49,0.001,1KG_EAS_AF,OPA1
611516,3:193391823:G>T,NM_130837.2:c.2983+6754G>T,\N,\N,29/30,Benign,\N,intron_variant,9.571,0.0865,1KG_EUR_AF,OPA1
611517,3:193391829:G>C,NM_130837.2:c.2983+6760G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.629,\N,\N,OPA1
611518,3:193391836:C>T,NM_130837.2:c.2983+6767C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,13.78,\N,\N,OPA1
611519,3:193391837:G>A,NM_130837.2:c.2983+6768G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,11.76,0.001,1KG_EUR_AF,OPA1
611520,3:193391842:C>T,NM_130837.2:c.2983+6773C>T,\N,\N,29/30,Benign,\N,intron_variant,19.17,0.005,1KG_EAS_AF,OPA1
611521,3:193391903:G>A,NM_130837.2:c.2983+6834G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,16.52,\N,\N,OPA1
611522,3:193391941:G>A,NM_130837.2:c.2983+6872G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,20.3,\N,\N,OPA1
611523,3:193392000:T>G,NM_130837.2:c.2983+6931T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,14.75,\N,\N,OPA1
611524,3:193392003:T>C,NM_130837.2:c.2983+6934T>C,\N,\N,29/30,Benign,\N,intron_variant,11.2,0.0179,1KG_EAS_AF,OPA1
611525,3:193392053:C>T,NM_130837.2:c.2983+6984C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,14.83,0.001,1KG_EUR_AF,OPA1
611526,3:193392068:C>T,NM_130837.2:c.2983+6999C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,3.948,\N,\N,OPA1
611527,3:193392130:C>G,NM_130837.2:c.2983+7061C>G,\N,\N,29/30,Benign,\N,intron_variant,3.977,0.0076,1KG_AFR_AF,OPA1
611528,3:193392170:T>C,NM_130837.2:c.2983+7101T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.202,\N,\N,OPA1
611529,3:193392197:A>G,NM_130837.2:c.2983+7128A>G,\N,\N,29/30,Benign,\N,intron_variant,1.713,0.0875,1KG_EUR_AF,OPA1
611530,3:193392227:T>C,NM_130837.2:c.2983+7158T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.155,0.001,1KG_EUR_AF,OPA1
611531,3:193392281:A>G,NM_130837.2:c.2983+7212A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,11.68,\N,\N,OPA1
611532,3:193392336:C>T,NM_130837.2:c.2983+7267C>T,\N,\N,29/30,Benign,\N,intron_variant,2.037,0.138,1KG_SAS_AF,OPA1
611533,3:193392474:A>G,NM_130837.2:c.2983+7405A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.846,\N,\N,OPA1
611534,3:193392531:C>T,NM_130837.2:c.2983+7462C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,6.683,0.0008,1KG_AFR_AF,OPA1
611535,3:193392547:A>G,NM_130837.2:c.2983+7478A>G,\N,\N,29/30,Benign,\N,intron_variant,1.703,0.0367,1KG_EAS_AF,OPA1
611536,3:193392555:G>A,NM_130837.2:c.2983+7486G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,4.53,0.0015,1KG_AFR_AF,OPA1
611537,3:193392564:C>T,NM_130837.2:c.2983+7495C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,4.151,0.001,1KG_SAS_AF,OPA1
611538,3:193392565:G>A,NM_130837.2:c.2983+7496G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,5.736,0.002,1KG_EAS_AF,OPA1
611539,3:193392566:G>A,NM_130837.2:c.2983+7497G>A,\N,\N,29/30,Benign,\N,intron_variant,2.235,0.0133,1KG_SAS_AF,OPA1
611540,3:193392636:G>C,NM_130837.2:c.2983+7567G>C,\N,\N,29/30,Benign,\N,intron_variant,0.788,0.1384,1KG_AFR_AF,OPA1
611541,3:193392636:GGA>CTAC,NM_130837.2:c.2983+7567_2983+7569delinsCTAC,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611542,3:193392637:G>T,NM_130837.2:c.2983+7568G>T,\N,\N,29/30,Benign,\N,intron_variant,0.998,0.1384,1KG_AFR_AF,OPA1
611543,3:193392638:A>AC,NM_130837.2:c.2983+7569_2983+7570insC,\N,\N,29/30,Benign,\N,intron_variant,0.472,0.1377,1KG_AFR_AF,OPA1
611544,3:193392642:G>GA,NM_130837.2:c.2983+7577dup,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611545,3:193392652:G>A,NM_130837.2:c.2983+7583G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,4.682,\N,\N,OPA1
611546,3:193392659:G>A,NM_130837.2:c.2983+7590G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.888,\N,\N,OPA1
611547,3:193392659:G>T,NM_130837.2:c.2983+7590G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.253,\N,\N,OPA1
611548,3:193392685:G>A,NM_130837.2:c.2983+7616G>A,\N,\N,29/30,Benign,\N,intron_variant,4.352,0.0058,1KG_AMR_AF,OPA1
611549,3:193392691:G>A,NM_130837.2:c.2983+7622G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,4.864,\N,\N,OPA1
611550,3:193392710:T>G,NM_130837.2:c.2983+7641T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.79,\N,\N,OPA1
611551,3:193392724:A>G,NM_130837.2:c.2983+7655A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.408,0.001,1KG_EUR_AF,OPA1
611552,3:193392742:C>G,NM_130837.2:c.2983+7673C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.355,0.0023,1KG_AFR_AF,OPA1
611553,3:193392752:C>T,NM_130837.2:c.2983+7683C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.047,0.0008,1KG_AFR_AF,OPA1
611554,3:193392760:C>T,NM_130837.2:c.2983+7691C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,8.021,0.002,1KG_SAS_AF,OPA1
611555,3:193392761:G>A,NM_130837.2:c.2983+7692G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.68,0.001,1KG_SAS_AF,OPA1
611556,3:193392787:G>T,NM_130837.2:c.2983+7718G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,4.519,0.001,1KG_EUR_AF,OPA1
611557,3:193392792:C>A,NM_130837.2:c.2983+7723C>A,\N,\N,29/30,Unknown significance,\N,intron_variant,6.379,\N,\N,OPA1
611558,3:193392806:C>A,NM_130837.2:c.2983+7737C>A,\N,\N,29/30,Unknown significance,\N,intron_variant,5.969,\N,\N,OPA1
611559,3:193392810:A>G,NM_130837.2:c.2983+7741A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.306,0.001,1KG_SAS_AF,OPA1
611560,3:193392823:C>G,NM_130837.2:c.2983+7754C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,5.373,0.0008,1KG_AFR_AF,OPA1
611561,3:193392849:C>T,NM_130837.2:c.2983+7780C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.128,\N,\N,OPA1
611562,3:193392870:A>G,NM_130837.2:c.2983+7801A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.559,\N,\N,OPA1
611563,3:193392911:G>T,NM_130837.2:c.2983+7842G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.618,\N,\N,OPA1
611564,3:193392986:C>T,NM_130837.2:c.2983+7917C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,5.359,0.0014,1KG_AMR_AF,OPA1
611565,3:193393003:T>C,NM_130837.2:c.2983+7934T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,4.027,0.001,1KG_SAS_AF,OPA1
611566,3:193393044:A>G,NM_130837.2:c.2983+7975A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,17.11,\N,\N,OPA1
611567,3:193393055:G>A,NM_130837.2:c.2983+7986G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,16.25,0.001,1KG_SAS_AF,OPA1
611568,3:193393087:T>A,NM_130837.2:c.2983+8018T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,6.407,0.001,1KG_EAS_AF,OPA1
611569,3:193393095:G>A,NM_130837.2:c.2983+8026G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.901,0.0038,1KG_AFR_AF,OPA1
611570,3:193393101:A>AT,NM_130837.2:c.2983+8044dup,\N,\N,29/30,Benign,\N,intron_variant,6.661,0.0367,1KG_EAS_AF,OPA1
611571,3:193393116:G>A,NM_130837.2:c.2983+8047G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.012,\N,\N,OPA1
611572,3:193393122:A>AAAAAAC,NM_130837.2:c.2983+8058_2983+8059insCAAAAA,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611573,3:193393126:A>AC,NM_130837.2:c.2983+8057_2983+8058insC,\N,\N,29/30,Unknown significance,\N,intron_variant,0.098,\N,\N,OPA1
611574,3:193393127:A>AC,NM_130837.2:c.2983+8058_2983+8059insC,\N,\N,29/30,Benign,\N,intron_variant,0.114,0.3241,1KG_EUR_AF,OPA1
611575,3:193393127:A>C,NM_130837.2:c.2983+8058A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.446,\N,\N,OPA1
611576,3:193393128:A>AAAAAC,NM_130837.2:c.2983+8063_2983+8064insCAAAA,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611577,3:193393128:A>AC,NM_130837.2:c.2983+8059_2983+8060insC,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611578,3:193393133:A>C,NM_130837.2:c.2983+8064A>C,\N,\N,29/30,Benign,\N,intron_variant,0.573,0.3691,1KG_SAS_AF,OPA1
611579,3:193393139:A>C,NM_130837.2:c.2983+8070A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.04,\N,\N,OPA1
611580,3:193393140:C>A,NM_130837.2:c.2983+8071C>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.821,\N,\N,OPA1
611581,3:193393141:A>C,NM_130837.2:c.2983+8072A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.949,\N,\N,OPA1
611582,3:193393176:G>A,NM_130837.2:c.2983+8107G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,3.016,\N,\N,OPA1
611583,3:193393178:G>A,NM_130837.2:c.2983+8109G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,3.666,\N,\N,OPA1
611584,3:193393181:C>T,NM_130837.2:c.2983+8112C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.003,0.001,1KG_EAS_AF,OPA1
611585,3:193393182:G>A,NM_130837.2:c.2983+8113G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.072,\N,\N,OPA1
611586,3:193393184:G>A,NM_130837.2:c.2983+8115G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.259,0.001,1KG_EUR_AF,OPA1
611587,3:193393201:C>T,NM_130837.2:c.2983+8132C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,3.333,0.001,1KG_EAS_AF,OPA1
611588,3:193393210:C>T,NM_130837.2:c.2983+8141C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,5.904,\N,\N,OPA1
611589,3:193393217:A>G,NM_130837.2:c.2983+8148A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.948,\N,\N,OPA1
611590,3:193393253:C>T,NM_130837.2:c.2983+8184C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.221,\N,\N,OPA1
611591,3:193393266:C>T,NM_130837.2:c.2983+8197C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,3.716,\N,\N,OPA1
611592,3:193393288:G>T,NM_130837.2:c.2983+8219G>T,\N,\N,29/30,Benign,\N,intron_variant,0.54,0.0218,1KG_EAS_AF,OPA1
611593,3:193393288:GAGGC>G,NM_130837.2:c.2983+8221_2983+8224del,\N,\N,29/30,Benign,\N,intron_variant,2.463,0.0265,1KG_AFR_AF,OPA1
611594,3:193393317:A>G,NM_130837.2:c.2983+8248A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,4.444,0.0008,1KG_AFR_AF,OPA1
611595,3:193393330:C>T,NM_130837.2:c.2983+8261C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.697,0.0014,1KG_AMR_AF,OPA1
611596,3:193393331:G>A,NM_130837.2:c.2983+8262G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.11,0.0023,1KG_AFR_AF,OPA1
611597,3:193393352:C>T,NM_130837.2:c.2983+8283C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,4.951,0.0008,1KG_AFR_AF,OPA1
611598,3:193393384:G>C,NM_130837.2:c.2983+8315G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.05,0.003,1KG_AFR_AF,OPA1
611599,3:193393389:T>C,NM_130837.2:c.2983+8320T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,7.423,0.001,1KG_SAS_AF,OPA1
611600,3:193393423:G>A,NM_130837.2:c.2983+8354G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.48,\N,\N,OPA1
611601,3:193393437:T>G,NM_130837.2:c.2983+8368T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,6.588,0.0008,1KG_AFR_AF,OPA1
611602,3:193393533:G>A,NM_130837.2:c.2983+8464G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,3.379,\N,\N,OPA1
611603,3:193393551:A>C,NM_130837.2:c.2983+8482A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.856,\N,\N,OPA1
611604,3:193393587:G>A,NM_130837.2:c.2983+8518G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.162,0.0014,1KG_AMR_AF,OPA1
611605,3:193393589:G>A,NM_130837.2:c.2983+8520G>A,\N,\N,29/30,Benign,\N,intron_variant,1.594,0.0051,1KG_SAS_AF,OPA1
611606,3:193393608:A>T,NM_130837.2:c.2983+8539A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.764,0.001,1KG_EAS_AF,OPA1
611607,3:193393612:A>G,NM_130837.2:c.2983+8543A>G,\N,\N,29/30,Benign,\N,intron_variant,3.13,0.5855,1KG_AFR_AF,OPA1
611608,3:193393622:T>G,NM_130837.2:c.2983+8553T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,4.721,0.003,1KG_EUR_AF,OPA1
611609,3:193393627:G>A,NM_130837.2:c.2983+8558G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.737,\N,\N,OPA1
611610,3:193393690:G>A,NM_130837.2:c.2983+8621G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.045,0.001,1KG_EUR_AF,OPA1
611611,3:193393709:C>G,NM_130837.2:c.2983+8640C>G,\N,\N,29/30,Benign,\N,intron_variant,0.286,0.0072,1KG_SAS_AF,OPA1
611612,3:193393716:A>G,NM_130837.2:c.2983+8647A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.526,\N,\N,OPA1
611613,3:193393764:T>C,NM_130837.2:c.2983+8695T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,3,\N,\N,OPA1
611614,3:193393786:A>G,NM_130837.2:c.2983+8717A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,4.356,0.001,1KG_EAS_AF,OPA1
611615,3:193393822:G>A,NM_130837.2:c.2983+8753G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.33,0.0029,1KG_AMR_AF,OPA1
611616,3:193393833:C>G,NM_130837.2:c.2983+8764C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.117,\N,\N,OPA1
611617,3:193393842:A>G,NM_130837.2:c.2983+8773A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.775,\N,\N,OPA1
611618,3:193393859:T>C,NM_130837.2:c.2983+8790T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.589,0.0008,1KG_AFR_AF,OPA1
611619,3:193393879:C>G,NM_130837.2:c.2983+8810C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,5.103,\N,\N,OPA1
611620,3:193393914:T>C,NM_130837.2:c.2983+8845T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.736,\N,\N,OPA1
611621,3:193393960:C>T,NM_130837.2:c.2983+8891C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,13.16,0.0014,1KG_AMR_AF,OPA1
611622,3:193393998:A>G,NM_130837.2:c.2983+8929A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.236,\N,\N,OPA1
611623,3:193394002:G>A,NM_130837.2:c.2983+8933G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.754,\N,\N,OPA1
611624,3:193394024:T>C,NM_130837.2:c.2983+8955T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.673,\N,\N,OPA1
611625,3:193394027:A>AT,NM_130837.2:c.2983+8967dup,\N,\N,29/30,Benign,\N,intron_variant,0.137,0.5726,1KG_AFR_AF,OPA1
611626,3:193394038:C>A,NM_130837.2:c.2983+8969C>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.096,\N,\N,OPA1
611627,3:193394038:C>T,NM_130837.2:c.2983+8969C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.321,\N,\N,OPA1
611628,3:193394072:A>G,NM_130837.2:c.2983+9003A>G,\N,\N,29/30,Benign,\N,intron_variant,3.647,0.062,1KG_AFR_AF,OPA1
611629,3:193394073:T>C,NM_130837.2:c.2983+9004T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.865,\N,\N,OPA1
611630,3:193394080:A>G,NM_130837.2:c.2983+9011A>G,\N,\N,29/30,Benign,\N,intron_variant,4.026,0.1501,1KG_EUR_AF,OPA1
611631,3:193394082:T>A,NM_130837.2:c.2983+9013T>A,\N,\N,29/30,Benign,\N,intron_variant,5.807,0.0179,1KG_EAS_AF,OPA1
611632,3:193394083:A>G,NM_130837.2:c.2983+9014A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.98,0.0008,1KG_AFR_AF,OPA1
611633,3:193394102:T>C,NM_130837.2:c.2983+9033T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,5.268,\N,\N,OPA1
611634,3:193394153:T>A,NM_130837.2:c.2983+9084T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,11.23,\N,\N,OPA1
611635,3:193394176:A>G,NM_130837.2:c.2983+9107A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.758,\N,\N,OPA1
611636,3:193394230:T>C,NM_130837.2:c.2983+9161T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.106,\N,\N,OPA1
611637,3:193394231:A>G,NM_130837.2:c.2983+9162A>G,\N,\N,29/30,Benign,\N,intron_variant,3.866,0.0133,1KG_SAS_AF,OPA1
611638,3:193394245:C>T,NM_130837.2:c.2983+9176C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,3.994,\N,\N,OPA1
611639,3:193394254:G>T,NM_130837.2:c.2983+9185G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,3.037,0.0014,1KG_AMR_AF,OPA1
611640,3:193394270:A>G,NM_130837.2:c.2983+9201A>G,\N,\N,29/30,Benign,\N,intron_variant,4.096,0.0333,1KG_AFR_AF,OPA1
611641,3:193394297:A>G,NM_130837.2:c.2983+9228A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,9.815,\N,\N,OPA1
611642,3:193394309:A>G,NM_130837.2:c.2983+9240A>G,\N,\N,29/30,Benign,\N,intron_variant,8.775,0.2376,1KG_EUR_AF,OPA1
611643,3:193394320:A>G,NM_130837.2:c.2983+9251A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,4.614,0.001,1KG_SAS_AF,OPA1
611644,3:193394373:C>T,NM_130837.2:c.2983+9304C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.07,0.002,1KG_EAS_AF,OPA1
611645,3:193394412:T>C,NM_130837.2:c.2983+9343T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,16.12,\N,\N,OPA1
611646,3:193394482:C>T,NM_130837.2:c.2983+9413C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,3.182,0.004,1KG_EAS_AF,OPA1
611647,3:193394491:C>T,NM_130837.2:c.2983+9422C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.134,0.001,1KG_SAS_AF,OPA1
611648,3:193394493:G>GGT,NM_130837.2:c.2983+9428_2983+9429dup,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611649,3:193394495:T>A,NM_130837.2:c.2983+9426T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.804,\N,\N,OPA1
611650,3:193394495:T>C,NM_130837.2:c.2983+9426T>C,\N,\N,29/30,Benign,\N,intron_variant,0.122,0.6587,1KG_EAS_AF,OPA1
611651,3:193394495:TGT>CGC,NM_130837.2:c.2983+9426_2983+9428delinsCGC,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611652,3:193394496:G>A,NM_130837.2:c.2983+9427G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.891,\N,\N,OPA1
611653,3:193394497:T>C,NM_130837.2:c.2983+9428T>C,\N,\N,29/30,Benign,\N,intron_variant,0.831,0.7073,1KG_EAS_AF,OPA1
611654,3:193394497:T>CGC,NM_130837.2:c.2983+9428delinsCGC,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611655,3:193394498:G>A,NM_130837.2:c.2983+9429G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.288,\N,\N,OPA1
611656,3:193394500:T>C,NM_130837.2:c.2983+9431T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.121,0.001,1KG_EAS_AF|1KG_SAS_AF,OPA1
611657,3:193394505:C>T,NM_130837.2:c.2983+9436C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.095,0.001,1KG_SAS_AF,OPA1
611658,3:193394506:A>C,NM_130837.2:c.2983+9437A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.685,\N,\N,OPA1
611659,3:193394509:C>T,NM_130837.2:c.2983+9440C>T,\N,\N,29/30,Benign,\N,intron_variant,2.289,0.0159,1KG_EUR_AF,OPA1
611660,3:193394514:A>G,NM_130837.2:c.2983+9445A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.08,0.0008,1KG_AFR_AF,OPA1
611661,3:193394528:A>G,NM_130837.2:c.2983+9459A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.231,0.002,1KG_EAS_AF,OPA1
611662,3:193394536:A>G,NM_130837.2:c.2983+9467A>G,\N,\N,29/30,Benign,\N,intron_variant,0.187,0.4911,1KG_EAS_AF,OPA1
611663,3:193394540:T>A,NM_130837.2:c.2983+9471T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.004,\N,\N,OPA1
611664,3:193394540:T>C,NM_130837.2:c.2983+9471T>C,\N,\N,29/30,Benign,\N,intron_variant,0.222,0.4901,1KG_EAS_AF,OPA1
611665,3:193394544:C>T,NM_130837.2:c.2983+9475C>T,\N,\N,29/30,Benign,\N,intron_variant,2.638,0.005,1KG_EAS_AF,OPA1
611666,3:193394545:G>A,NM_130837.2:c.2983+9476G>A,\N,\N,29/30,Benign,\N,intron_variant,1.985,0.0212,1KG_AFR_AF,OPA1
611667,3:193394552:A>G,NM_130837.2:c.2983+9483A>G,\N,\N,29/30,Benign,\N,intron_variant,2.531,0.0212,1KG_AFR_AF,OPA1
611668,3:193394554:G>A,NM_130837.2:c.2983+9485G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,4.207,\N,\N,OPA1
611669,3:193394565:C>T,NM_130837.2:c.2983+9496C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,3.201,0.0029,1KG_AMR_AF,OPA1
611670,3:193394565:CC>GG,NM_130837.2:c.2983+9496_2983+9497inv,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611671,3:193394566:C>G,NM_130837.2:c.2983+9497C>G,\N,\N,29/30,Benign,\N,intron_variant,0.303,0.1346,1KG_AFR_AF,OPA1
611672,3:193394570:C>T,NM_130837.2:c.2983+9501C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.073,0.0014,1KG_AMR_AF,OPA1
611673,3:193394571:C>G,NM_130837.2:c.2983+9502C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.768,\N,\N,OPA1
611674,3:193394571:C>T,NM_130837.2:c.2983+9502C>T,\N,\N,29/30,Benign,\N,intron_variant,3.356,0.0865,1KG_EUR_AF,OPA1
611675,3:193394573:T>G,NM_130837.2:c.2983+9504T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.707,0.0041,1KG_SAS_AF,OPA1
611676,3:193394576:T>C,NM_130837.2:c.2983+9507T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.056,0.0029,1KG_AMR_AF,OPA1
611677,3:193394580:T>C,NM_130837.2:c.2983+9511T>C,\N,\N,29/30,Benign,\N,intron_variant,1.66,0.1799,1KG_EUR_AF,OPA1
611678,3:193394586:A>G,NM_130837.2:c.2983+9517A>G,\N,\N,29/30,Benign,\N,intron_variant,0.063,0.0204,1KG_AFR_AF,OPA1
611679,3:193394586:A>T,NM_130837.2:c.2983+9517A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.07,\N,\N,OPA1
611680,3:193394591:A>C,NM_130837.2:c.2983+9522A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.873,0.001,1KG_EAS_AF|1KG_SAS_AF,OPA1
611681,3:193394596:C>T,NM_130837.2:c.2983+9527C>T,\N,\N,29/30,Benign,\N,intron_variant,1.427,0.0257,1KG_AFR_AF,OPA1
611682,3:193394597:G>A,NM_130837.2:c.2983+9528G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.063,0.0008,1KG_AFR_AF,OPA1
611683,3:193394610:A>C,NM_130837.2:c.2983+9541A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.378,0.001,1KG_EAS_AF,OPA1
611684,3:193394613:C>T,NM_130837.2:c.2983+9544C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.537,0.001,1KG_EAS_AF,OPA1
611685,3:193394620:T>A,NM_130837.2:c.2983+9551T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.052,0.001,1KG_EAS_AF|1KG_SAS_AF,OPA1
611686,3:193394622:T>C,NM_130837.2:c.2983+9553T>C,\N,\N,29/30,Benign,\N,intron_variant,1.289,0.006,1KG_EUR_AF,OPA1
611687,3:193394624:G>A,NM_130837.2:c.2983+9555G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.025,0.0008,1KG_AFR_AF,OPA1
611688,3:193394627:A>G,NM_130837.2:c.2983+9558A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.288,0.003,1KG_AFR_AF,OPA1
611689,3:193394630:C>T,NM_130837.2:c.2983+9561C>T,\N,\N,29/30,Benign,\N,intron_variant,2.464,0.0053,1KG_AFR_AF,OPA1
611690,3:193394631:G>A,NM_130837.2:c.2983+9562G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.668,0.0008,1KG_AFR_AF,OPA1
611691,3:193394632:T>C,NM_130837.2:c.2983+9563T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.262,0.001,1KG_EUR_AF,OPA1
611692,3:193394634:G>A,NM_130837.2:c.2983+9565G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.039,\N,\N,OPA1
611693,3:193394638:C>T,NM_130837.2:c.2983+9569C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.71,0.001,1KG_EAS_AF|1KG_EUR_AF,OPA1
611694,3:193394639:G>A,NM_130837.2:c.2983+9570G>A,\N,\N,29/30,Benign,\N,intron_variant,0.186,0.0053,1KG_AFR_AF,OPA1
611695,3:193394642:C>T,NM_130837.2:c.2983+9573C>T,\N,\N,29/30,Benign,\N,intron_variant,3.319,0.0318,1KG_AFR_AF,OPA1
611696,3:193394643:G>A,NM_130837.2:c.2983+9574G>A,\N,\N,29/30,Benign,\N,intron_variant,2.773,0.0061,1KG_SAS_AF,OPA1
611697,3:193394643:G>C,NM_130837.2:c.2983+9574G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.506,\N,\N,OPA1
611698,3:193394649:A>G,NM_130837.2:c.2983+9580A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,4.875,0.0014,1KG_AMR_AF,OPA1
611699,3:193394651:T>G,NM_130837.2:c.2983+9582T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,5.842,0.001,1KG_EAS_AF,OPA1
611700,3:193394694:T>C,NM_130837.2:c.2983+9625T>C,\N,\N,29/30,Benign,\N,intron_variant,0.202,0.0092,1KG_SAS_AF,OPA1
611701,3:193394702:G>A,NM_130837.2:c.2983+9633G>A,\N,\N,29/30,Benign,\N,intron_variant,1.673,0.0089,1KG_EUR_AF,OPA1
611702,3:193394706:C>T,NM_130837.2:c.2983+9637C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.57,\N,\N,OPA1
611703,3:193394710:C>T,NM_130837.2:c.2983+9641C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.474,0.0041,1KG_SAS_AF,OPA1
611704,3:193394711:G>A,NM_130837.2:c.2983+9642G>A,\N,\N,29/30,Benign,\N,intron_variant,0.113,0.4175,1KG_AFR_AF,OPA1
611705,3:193394718:C>T,NM_130837.2:c.2983+9649C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.647,0.0008,1KG_AFR_AF,OPA1
611706,3:193394719:G>T,NM_130837.2:c.2983+9650G>T,\N,\N,29/30,Benign,\N,intron_variant,0.397,0.0051,1KG_SAS_AF,OPA1
611707,3:193394724:C>G,NM_130837.2:c.2983+9655C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.756,\N,\N,OPA1
611708,3:193394725:G>A,NM_130837.2:c.2983+9656G>A,\N,\N,29/30,Benign,\N,intron_variant,0.868,0.0367,1KG_EAS_AF,OPA1
611709,3:193394725:G>C,NM_130837.2:c.2983+9656G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.133,0.0015,1KG_AFR_AF,OPA1
611710,3:193394727:G>A,NM_130837.2:c.2983+9658G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.897,0.002,1KG_EUR_AF,OPA1
611711,3:193394731:C>T,NM_130837.2:c.2983+9662C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.325,0.001,1KG_SAS_AF,OPA1
611712,3:193394738:C>G,NM_130837.2:c.2983+9669C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.564,0.0045,1KG_AFR_AF,OPA1
611713,3:193394748:T>C,NM_130837.2:c.2983+9679T>C,\N,\N,29/30,Benign,\N,intron_variant,0.234,0.0885,1KG_EUR_AF,OPA1
611714,3:193394757:A>G,NM_130837.2:c.2983+9688A>G,\N,\N,29/30,Benign,\N,intron_variant,3.395,0.0875,1KG_EUR_AF,OPA1
611715,3:193394762:T>TC,NM_130837.2:c.2983+9694dup,\N,\N,29/30,Benign,\N,intron_variant,1.087,0.0865,1KG_EUR_AF,OPA1
611716,3:193394763:C>T,NM_130837.2:c.2983+9694C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.314,0.002,1KG_EAS_AF,OPA1
611717,3:193394768:CA>C,NM_130837.2:c.2983+9724del,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611718,3:193394768:CAA>C,NM_130837.2:c.2983+9723_2983+9724del,\N,\N,29/30,Unknown significance,\N,intron_variant,5.558,\N,\N,OPA1
611719,3:193394769:A>C,NM_130837.2:c.2983+9700A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.582,\N,\N,OPA1
611720,3:193394785:A>C,NM_130837.2:c.2983+9716A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.95,\N,\N,OPA1
611721,3:193394806:G>A,NM_130837.2:c.2983+9737G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.279,\N,\N,OPA1
611722,3:193394819:T>A,NM_130837.2:c.2983+9750T>A,\N,\N,29/30,Benign,\N,intron_variant,5.468,0.0367,1KG_EAS_AF,OPA1
611723,3:193394830:G>A,NM_130837.2:c.2983+9761G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.282,0.001,1KG_EAS_AF|1KG_SAS_AF,OPA1
611724,3:193394836:G>A,NM_130837.2:c.2983+9767G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.808,\N,\N,OPA1
611725,3:193394837:A>G,NM_130837.2:c.2983+9768A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.57,0.002,1KG_EAS_AF,OPA1
611726,3:193394847:T>C,NM_130837.2:c.2983+9778T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.948,\N,\N,OPA1
611727,3:193394852:A>G,NM_130837.2:c.2983+9783A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.55,\N,\N,OPA1
611728,3:193394902:C>T,NM_130837.2:c.2983+9833C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.901,\N,\N,OPA1
611729,3:193394934:A>T,NM_130837.2:c.2983+9865A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.924,\N,\N,OPA1
611730,3:193394968:A>G,NM_130837.2:c.2983+9899A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.698,\N,\N,OPA1
611731,3:193394998:T>G,NM_130837.2:c.2983+9929T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.528,\N,\N,OPA1
611732,3:193395000:T>G,NM_130837.2:c.2983+9931T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,5.784,\N,\N,OPA1
611733,3:193395058:A>C,NM_130837.2:c.2983+9989A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.848,\N,\N,OPA1
611734,3:193395075:TACTTC>T,NM_130837.2:c.2983+10007_2983+10011del,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611735,3:193395080:C>CT,NM_130837.2:c.2983+10029dup,\N,\N,29/30,Unknown significance,\N,intron_variant,3.268,\N,\N,OPA1
611736,3:193395080:C>CTT,NM_130837.2:c.2983+10028_2983+10029dup,\N,\N,29/30,Unknown significance,\N,intron_variant,3.101,\N,\N,OPA1
611737,3:193395081:T>C,NM_130837.2:c.2983+10012T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.921,\N,\N,OPA1
611738,3:193395099:C>T,NM_130837.2:c.2983+10030C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.944,\N,\N,OPA1
611739,3:193395104:G>A,NM_130837.2:c.2983+10035G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.403,\N,\N,OPA1
611740,3:193395109:A>T,NM_130837.2:c.2983+10040A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.91,0.0008,1KG_AFR_AF,OPA1
611741,3:193395110:G>A,NM_130837.2:c.2983+10041G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.911,\N,\N,OPA1
611742,3:193395168:G>A,NM_130837.2:c.2983+10099G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.894,0.001,1KG_EUR_AF,OPA1
611743,3:193395170:A>G,NM_130837.2:c.2983+10101A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.714,\N,\N,OPA1
611744,3:193395209:A>T,NM_130837.2:c.2983+10140A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.367,0.0015,1KG_AFR_AF,OPA1
611745,3:193395228:G>A,NM_130837.2:c.2983+10159G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.044,0.0038,1KG_AFR_AF,OPA1
611746,3:193395249:T>C,NM_130837.2:c.2983+10180T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,4.965,0.001,1KG_EUR_AF,OPA1
611747,3:193395315:G>A,NM_130837.2:c.2983+10246G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.477,0.002,1KG_EAS_AF,OPA1
611748,3:193395330:T>C,NM_130837.2:c.2983+10261T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,3.151,0.0029,1KG_AMR_AF,OPA1
611749,3:193395335:A>G,NM_130837.2:c.2983+10266A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.31,\N,\N,OPA1
611750,3:193395350:G>A,NM_130837.2:c.2983+10281G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.59,0.0015,1KG_AFR_AF,OPA1
611751,3:193395368:G>A,NM_130837.2:c.2983+10299G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.338,0.0015,1KG_AFR_AF,OPA1
611752,3:193395371:T>C,NM_130837.2:c.2983+10302T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.993,\N,\N,OPA1
611753,3:193395417:T>C,NM_130837.2:c.2983+10348T>C,\N,\N,29/30,Benign,\N,intron_variant,1.635,0.0113,1KG_AFR_AF,OPA1
611754,3:193395511:C>T,NM_130837.2:c.2983+10442C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.8,0.0008,1KG_AFR_AF,OPA1
611755,3:193395527:G>A,NM_130837.2:c.2983+10458G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.882,0.0015,1KG_AFR_AF,OPA1
611756,3:193395539:C>G,NM_130837.2:c.2983+10470C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.448,0.002,1KG_EAS_AF,OPA1
611757,3:193395568:A>G,NM_130837.2:c.2983+10499A>G,\N,\N,29/30,Benign,\N,intron_variant,3.246,0.0053,1KG_AFR_AF,OPA1
611758,3:193395590:A>G,NM_130837.2:c.2983+10521A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.494,0.0014,1KG_AMR_AF,OPA1
611759,3:193395592:A>G,NM_130837.2:c.2983+10523A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.501,0.001,1KG_EAS_AF,OPA1
611760,3:193395596:G>T,NM_130837.2:c.2983+10527G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.624,\N,\N,OPA1
611761,3:193395606:A>T,NM_130837.2:c.2983+10537A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.614,0.001,1KG_SAS_AF,OPA1
611762,3:193395615:G>A,NM_130837.2:c.2983+10546G>A,\N,\N,29/30,Benign,\N,intron_variant,6.107,0.1619,1KG_AFR_AF,OPA1
611763,3:193395622:A>G,NM_130837.2:c.2983+10553A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.807,0.0008,1KG_AFR_AF,OPA1
611764,3:193395643:T>G,NM_130837.2:c.2983+10574T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,4.706,0.0008,1KG_AFR_AF,OPA1
611765,3:193395680:C>G,NM_130837.2:c.2983+10611C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.855,0.001,1KG_EUR_AF,OPA1
611766,3:193395687:G>A,NM_130837.2:c.2983+10618G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.048,0.0043,1KG_AMR_AF,OPA1
611767,3:193395696:C>T,NM_130837.2:c.2983+10627C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,4.129,\N,\N,OPA1
611768,3:193395712:G>C,NM_130837.2:c.2983+10643G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.585,\N,\N,OPA1
611769,3:193395715:G>C,NM_130837.2:c.2983+10646G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.35,0.001,1KG_EAS_AF,OPA1
611770,3:193395768:A>G,NM_130837.2:c.2983+10699A>G,\N,\N,29/30,Benign,\N,intron_variant,1.309,0.0092,1KG_SAS_AF,OPA1
611771,3:193395794:T>C,NM_130837.2:c.2983+10725T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.499,0.001,1KG_EAS_AF,OPA1
611772,3:193395801:C>T,NM_130837.2:c.2983+10732C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.399,0.001,1KG_SAS_AF,OPA1
611773,3:193395810:T>G,NM_130837.2:c.2983+10741T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.459,0.0015,1KG_AFR_AF,OPA1
611774,3:193395882:C>T,NM_130837.2:c.2983+10813C>T,\N,\N,29/30,Benign,\N,intron_variant,4.109,0.0257,1KG_AFR_AF,OPA1
611775,3:193395916:T>C,NM_130837.2:c.2983+10847T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,5.51,\N,\N,OPA1
611776,3:193395960:G>T,NM_130837.2:c.2983+10891G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.433,\N,\N,OPA1
611777,3:193396042:T>A,NM_130837.2:c.2983+10973T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,7.178,\N,\N,OPA1
611778,3:193396049:T>C,NM_130837.2:c.2983+10980T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,3.377,\N,\N,OPA1
611779,3:193396076:A>G,NM_130837.2:c.2983+11007A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,5.858,\N,\N,OPA1
611780,3:193396089:A>T,NM_130837.2:c.2983+11020A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.81,\N,\N,OPA1
611781,3:193396103:GT>G,NM_130837.2:c.2983+11045del,\N,\N,29/30,Unknown significance,\N,intron_variant,1.512,\N,\N,OPA1
611782,3:193396104:T>G,NM_130837.2:c.2983+11035T>G,\N,\N,29/30,Benign,\N,intron_variant,4.473,0.0179,1KG_EAS_AF,OPA1
611783,3:193396153:T>C,NM_130837.2:c.2983+11084T>C,\N,\N,29/30,Benign,\N,intron_variant,1.791,0.0053,1KG_AFR_AF,OPA1
611784,3:193396157:G>A,NM_130837.2:c.2983+11088G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.143,0.0008,1KG_AFR_AF,OPA1
611785,3:193396200:G>A,NM_130837.2:c.2983+11131G>A,\N,\N,29/30,Benign,\N,intron_variant,1.645,0.0119,1KG_EUR_AF,OPA1
611786,3:193396202:C>T,NM_130837.2:c.2983+11133C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.106,0.001,1KG_EAS_AF,OPA1
611787,3:193396229:A>G,NM_130837.2:c.2983+11160A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.895,0.0014,1KG_AMR_AF,OPA1
611788,3:193396308:T>C,NM_130837.2:c.2983+11239T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.295,0.0029,1KG_AMR_AF,OPA1
611789,3:193396319:C>T,NM_130837.2:c.2983+11250C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,6.663,\N,\N,OPA1
611790,3:193396329:G>A,NM_130837.2:c.2983+11260G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,5.762,0.0008,1KG_AFR_AF,OPA1
611791,3:193396362:C>T,NM_130837.2:c.2983+11293C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,3.726,0.0008,1KG_AFR_AF,OPA1
611792,3:193396448:A>G,NM_130837.2:c.2983+11379A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,6.696,0.001,1KG_EAS_AF,OPA1
611793,3:193396465:A>C,NM_130837.2:c.2983+11396A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.497,0.0008,1KG_AFR_AF,OPA1
611794,3:193396570:T>G,NM_130837.2:c.2983+11501T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.151,0.0038,1KG_AFR_AF,OPA1
611795,3:193396577:C>G,NM_130837.2:c.2983+11508C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,8.517,0.0008,1KG_AFR_AF,OPA1
611796,3:193396581:T>C,NM_130837.2:c.2983+11512T>C,\N,\N,29/30,Benign,\N,intron_variant,9.772,0.0069,1KG_EAS_AF,OPA1
611797,3:193396620:A>C,NM_130837.2:c.2983+11551A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,13.29,0.0008,1KG_AFR_AF,OPA1
611798,3:193396625:A>G,NM_130837.2:c.2983+11556A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,14.34,\N,\N,OPA1
611799,3:193396692:C>G,NM_130837.2:c.2983+11623C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,5.05,\N,\N,OPA1
611800,3:193396734:T>A,NM_130837.2:c.2983+11665T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.712,\N,\N,OPA1
611801,3:193396736:G>GT,NM_130837.2:c.2983+11676dup,\N,\N,29/30,Unknown significance,\N,intron_variant,0.232,0.0014,1KG_AMR_AF,OPA1
611802,3:193396737:T>G,NM_130837.2:c.2983+11668T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.481,\N,\N,OPA1
611803,3:193396745:TC>T,NM_130837.2:c.2983+11679del,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611804,3:193396748:C>T,NM_130837.2:c.2983+11679C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,4.9,0.001,1KG_SAS_AF,OPA1
611805,3:193396752:AT>A,NM_130837.2:c.2983+11685del,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611806,3:193396788:A>G,NM_130837.2:c.2983+11719A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.838,\N,\N,OPA1
611807,3:193396803:G>C,NM_130837.2:c.2983+11734G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.376,\N,\N,OPA1
611808,3:193396843:C>T,NM_130837.2:c.2983+11774C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,5.145,0.0014,1KG_AMR_AF,OPA1
611809,3:193396904:C>T,NM_130837.2:c.2983+11835C>T,\N,\N,29/30,Benign,\N,intron_variant,1.51,0.0169,1KG_EAS_AF,OPA1
611810,3:193396922:C>T,NM_130837.2:c.2983+11853C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.043,\N,\N,OPA1
611811,3:193396923:G>A,NM_130837.2:c.2983+11854G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.175,\N,\N,OPA1
611812,3:193396928:G>A,NM_130837.2:c.2983+11859G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.959,0.0023,1KG_AFR_AF,OPA1
611813,3:193396937:G>A,NM_130837.2:c.2983+11868G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.916,0.0014,1KG_AMR_AF,OPA1
611814,3:193396957:A>C,NM_130837.2:c.2983+11888A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.099,\N,\N,OPA1
611815,3:193396977:C>T,NM_130837.2:c.2983+11908C>T,\N,\N,29/30,Benign,\N,intron_variant,2.622,0.0265,1KG_AFR_AF,OPA1
611816,3:193396995:G>T,NM_130837.2:c.2983+11926G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.842,\N,\N,OPA1
611817,3:193397022:CTTTTG>C,NM_130837.2:c.2983+11958_2983+11962del,\N,\N,29/30,Unknown significance,\N,intron_variant,2.482,\N,\N,OPA1
611818,3:193397022:CTTTTGT>C,NM_130837.2:c.2983+11970_2983+11975del,\N,\N,29/30,Unknown significance,\N,intron_variant,2.353,\N,\N,OPA1
611819,3:193397056:A>G,NM_130837.2:c.2983+11987A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.353,0.0023,1KG_AFR_AF,OPA1
611820,3:193397057:C>T,NM_130837.2:c.2983+11988C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.989,\N,\N,OPA1
611821,3:193397061:GA>G,NM_130837.2:c.2983+12000del,\N,\N,29/30,Unknown significance,\N,intron_variant,0.015,\N,\N,OPA1
611822,3:193397067:A>G,NM_130837.2:c.2983+11998A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.462,\N,\N,OPA1
611823,3:193397096:AAGAG>A,NM_130837.2:c.2983+12030_2983+12033del,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,0.0029,1KG_AMR_AF,OPA1
611824,3:193397104:G>C,NM_130837.2:c.2983+12035G>C,\N,\N,29/30,Benign,\N,intron_variant,0.008,0.0159,1KG_EAS_AF,OPA1
611825,3:193397128:T>TC,NM_130837.2:c.2983+12061dup,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611826,3:193397139:G>A,NM_130837.2:c.2983+12070G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,5.384,\N,\N,OPA1
611827,3:193397177:ACT>A,NM_130837.2:c.2983+12111_2983+12112del,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611828,3:193397192:C>T,NM_130837.2:c.2983+12123C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.573,\N,\N,OPA1
611829,3:193397209:G>C,NM_130837.2:c.2983+12140G>C,\N,\N,29/30,Benign,\N,intron_variant,0.333,0.062,1KG_AFR_AF,OPA1
611830,3:193397235:C>G,NM_130837.2:c.2983+12166C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.282,0.0008,1KG_AFR_AF,OPA1
611831,3:193397239:T>G,NM_130837.2:c.2983+12170T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.319,\N,\N,OPA1
611832,3:193397303:C>T,NM_130837.2:c.2983+12234C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.114,\N,\N,OPA1
611833,3:193397352:A>G,NM_130837.2:c.2983+12283A>G,\N,\N,29/30,Benign,\N,intron_variant,10.86,0.0144,1KG_AMR_AF,OPA1
611834,3:193397392:T>A,NM_130837.2:c.2983+12323T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.276,0.001,1KG_EAS_AF,OPA1
611835,3:193397500:G>A,NM_130837.2:c.2984-12352G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.991,0.001,1KG_EAS_AF,OPA1
611836,3:193397504:C>T,NM_130837.2:c.2984-12348C>T,\N,\N,29/30,Benign,\N,intron_variant,0.633,0.0051,1KG_SAS_AF,OPA1
611837,3:193397505:G>A,NM_130837.2:c.2984-12347G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.366,0.0015,1KG_AFR_AF,OPA1
611838,3:193397518:A>G,NM_130837.2:c.2984-12334A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.09,0.0029,1KG_AMR_AF,OPA1
611839,3:193397520:A>G,NM_130837.2:c.2984-12332A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,4.04,\N,\N,OPA1
611840,3:193397548:C>T,NM_130837.2:c.2984-12304C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,4.232,\N,\N,OPA1
611841,3:193397550:TA>T,NM_130837.2:c.2984-12300del,\N,\N,29/30,Unknown significance,\N,intron_variant,8.373,0.0023,1KG_AFR_AF,OPA1
611842,3:193397598:G>A,NM_130837.2:c.2984-12254G>A,\N,\N,29/30,Benign,\N,intron_variant,4.54,0.0133,1KG_SAS_AF,OPA1
611843,3:193397627:T>C,NM_130837.2:c.2984-12225T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,10.38,0.001,1KG_SAS_AF,OPA1
611844,3:193397634:A>G,NM_130837.2:c.2984-12218A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.591,0.001,1KG_EUR_AF,OPA1
611845,3:193397670:G>A,NM_130837.2:c.2984-12182G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.848,0.0014,1KG_AMR_AF,OPA1
611846,3:193397675:A>G,NM_130837.2:c.2984-12177A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.084,0.0008,1KG_AFR_AF,OPA1
611847,3:193397691:T>G,NM_130837.2:c.2984-12161T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,7.004,0.001,1KG_EAS_AF,OPA1
611848,3:193397701:GT>G,NM_130837.2:c.2984-12149del,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611849,3:193397711:T>C,NM_130837.2:c.2984-12141T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,10.09,\N,\N,OPA1
611850,3:193397736:G>A,NM_130837.2:c.2984-12116G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,8.131,0.002,1KG_EAS_AF,OPA1
611851,3:193397746:A>G,NM_130837.2:c.2984-12106A>G,\N,\N,29/30,Benign,\N,intron_variant,9.592,0.1248,1KG_AFR_AF,OPA1
611852,3:193397761:G>A,NM_130837.2:c.2984-12091G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.727,\N,\N,OPA1
611853,3:193397770:G>A,NM_130837.2:c.2984-12082G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.809,\N,\N,OPA1
611854,3:193397774:A>C,NM_130837.2:c.2984-12078A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.842,0.0008,1KG_AFR_AF,OPA1
611855,3:193397789:C>T,NM_130837.2:c.2984-12063C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.205,\N,\N,OPA1
611856,3:193397799:C>T,NM_130837.2:c.2984-12053C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,4.932,\N,\N,OPA1
611857,3:193397808:A>T,NM_130837.2:c.2984-12044A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,5.732,0.0008,1KG_AFR_AF,OPA1
611858,3:193397914:A>G,NM_130837.2:c.2984-11938A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.139,0.0014,1KG_AMR_AF,OPA1
611859,3:193397946:C>CT,NM_130837.2:c.2984-11899dup,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611860,3:193397996:G>GATACTT,NM_130837.2:c.2984-11854_2984-11853insACTTAT,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611861,3:193397996:G>GATCTT,NM_130837.2:c.2984-11855_2984-11851dup,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611862,3:193397998:T>TCTTATA,NM_130837.2:c.2984-11851_2984-11850insATACTT,\N,\N,29/30,Benign,\N,intron_variant,5.555,0.5696,1KG_AFR_AF,OPA1
611863,3:193398002:T>A,NM_130837.2:c.2984-11850T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,3.697,0.004,1KG_EAS_AF,OPA1
611864,3:193398010:A>ACTTCT,NM_130837.2:c.2984-11842_2984-11841insCTTCT,\N,\N,29/30,Unknown significance,\N,intron_variant,1.087,0.003,1KG_EAS_AF,OPA1
611865,3:193398084:G>A,NM_130837.2:c.2984-11768G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,13.12,0.001,1KG_SAS_AF,OPA1
611866,3:193398121:A>G,NM_130837.2:c.2984-11731A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,13.49,\N,\N,OPA1
611867,3:193398135:G>A,NM_130837.2:c.2984-11717G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,13.89,0.0014,1KG_AMR_AF,OPA1
611868,3:193398150:G>A,NM_130837.2:c.2984-11702G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,13.06,\N,\N,OPA1
611869,3:193398151:C>T,NM_130837.2:c.2984-11701C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,14.29,\N,\N,OPA1
611870,3:193398152:G>A,NM_130837.2:c.2984-11700G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,13.9,\N,\N,OPA1
611871,3:193398165:A>G,NM_130837.2:c.2984-11687A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,13.11,\N,\N,OPA1
611872,3:193398188:C>G,NM_130837.2:c.2984-11664C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,13.78,\N,\N,OPA1
611873,3:193398190:G>T,NM_130837.2:c.2984-11662G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,12.39,0.001,1KG_SAS_AF,OPA1
611874,3:193398210:A>G,NM_130837.2:c.2984-11642A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,12.9,\N,\N,OPA1
611875,3:193398210:A>T,NM_130837.2:c.2984-11642A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,12.08,\N,\N,OPA1
611876,3:193398219:C>A,NM_130837.2:c.2984-11633C>A,\N,\N,29/30,Unknown significance,\N,intron_variant,16.42,0.0008,1KG_AFR_AF,OPA1
611877,3:193398230:G>C,NM_130837.2:c.2984-11622G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,11.74,\N,\N,OPA1
611878,3:193398235:G>T,NM_130837.2:c.2984-11617G>T,\N,\N,29/30,Benign,\N,intron_variant,12.73,0.0189,1KG_AFR_AF,OPA1
611879,3:193398272:G>T,NM_130837.2:c.2984-11580G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,12.12,\N,\N,OPA1
611880,3:193398297:C>T,NM_130837.2:c.2984-11555C>T,\N,\N,29/30,Benign,\N,intron_variant,15.43,0.0174,1KG_SAS_AF,OPA1
611881,3:193398331:G>A,NM_130837.2:c.2984-11521G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,14.08,0.0023,1KG_AFR_AF,OPA1
611882,3:193398347:G>C,NM_130837.2:c.2984-11505G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,14.91,0.003,1KG_EUR_AF,OPA1
611883,3:193398420:C>T,NM_130837.2:c.2984-11432C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.491,\N,\N,OPA1
611884,3:193398471:A>C,NM_130837.2:c.2984-11381A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.309,0.0023,1KG_AFR_AF,OPA1
611885,3:193398484:G>A,NM_130837.2:c.2984-11368G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,3.087,0.0008,1KG_AFR_AF,OPA1
611886,3:193398485:A>G,NM_130837.2:c.2984-11367A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.144,\N,\N,OPA1
611887,3:193398497:A>T,NM_130837.2:c.2984-11355A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,9.075,\N,\N,OPA1
611888,3:193398511:T>A,NM_130837.2:c.2984-11341T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,15.62,0.001,1KG_EAS_AF,OPA1
611889,3:193398512:A>G,NM_130837.2:c.2984-11340A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,12.41,\N,\N,OPA1
611890,3:193398554:C>T,NM_130837.2:c.2984-11298C>T,\N,\N,29/30,Benign,\N,intron_variant,12.74,0.0102,1KG_SAS_AF,OPA1
611891,3:193398643:C>G,NM_130837.2:c.2984-11209C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.669,\N,\N,OPA1
611892,3:193398670:C>T,NM_130837.2:c.2984-11182C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,4.09,\N,\N,OPA1
611893,3:193398703:A>G,NM_130837.2:c.2984-11149A>G,\N,\N,29/30,Benign,\N,intron_variant,2.656,0.007,1KG_EUR_AF,OPA1
611894,3:193398803:A>C,NM_130837.2:c.2984-11049A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.614,0.001,1KG_SAS_AF,OPA1
611895,3:193398821:G>A,NM_130837.2:c.2984-11031G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,5.882,0.001,1KG_EUR_AF,OPA1
611896,3:193398858:T>A,NM_130837.2:c.2984-10994T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,7.713,0.001,1KG_EAS_AF,OPA1
611897,3:193398867:GA>G,NM_130837.2:c.2984-10981del,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611898,3:193398904:G>T,NM_130837.2:c.2984-10948G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.592,\N,\N,OPA1
611899,3:193398936:A>G,NM_130837.2:c.2984-10916A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,7.176,\N,\N,OPA1
611900,3:193398998:C>T,NM_130837.2:c.2984-10854C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,3.867,0.001,1KG_SAS_AF,OPA1
611901,3:193399012:A>G,NM_130837.2:c.2984-10840A>G,\N,\N,29/30,Benign,\N,intron_variant,3.799,0.2718,1KG_EAS_AF,OPA1
611902,3:193399065:T>G,NM_130837.2:c.2984-10787T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,4.869,\N,\N,OPA1
611903,3:193399070:G>A,NM_130837.2:c.2984-10782G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.65,0.001,1KG_EAS_AF,OPA1
611904,3:193399079:G>T,NM_130837.2:c.2984-10773G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.394,0.001,1KG_EUR_AF,OPA1
611905,3:193399111:T>C,NM_130837.2:c.2984-10741T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.596,\N,\N,OPA1
611906,3:193399112:A>C,NM_130837.2:c.2984-10740A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.808,0.001,1KG_EUR_AF,OPA1
611907,3:193399113:T>C,NM_130837.2:c.2984-10739T>C,\N,\N,29/30,Benign,\N,intron_variant,2.179,0.0166,1KG_AFR_AF,OPA1
611908,3:193399134:AGTTT>A,NM_130837.2:c.2984-10713_2984-10710del,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611909,3:193399160:T>C,NM_130837.2:c.2984-10692T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,3.386,\N,\N,OPA1
611910,3:193399173:T>A,NM_130837.2:c.2984-10679T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,7.552,\N,\N,OPA1
611911,3:193399188:T>A,NM_130837.2:c.2984-10664T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,4.082,0.0008,1KG_AFR_AF,OPA1
611912,3:193399192:T>C,NM_130837.2:c.2984-10660T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.455,\N,\N,OPA1
611913,3:193399195:T>C,NM_130837.2:c.2984-10657T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.47,\N,\N,OPA1
611914,3:193399198:G>A,NM_130837.2:c.2984-10654G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.039,0.0014,1KG_AMR_AF,OPA1
611915,3:193399240:A>G,NM_130837.2:c.2984-10612A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.565,0.001,1KG_EAS_AF,OPA1
611916,3:193399250:T>C,NM_130837.2:c.2984-10602T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.965,\N,\N,OPA1
611917,3:193399288:T>A,NM_130837.2:c.2984-10564T>A,\N,\N,29/30,Benign,\N,intron_variant,7.846,0.4337,1KG_AMR_AF,OPA1
611918,3:193399291:T>C,NM_130837.2:c.2984-10561T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.841,\N,\N,OPA1
611919,3:193399312:A>G,NM_130837.2:c.2984-10540A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.491,\N,\N,OPA1
611920,3:193399315:G>A,NM_130837.2:c.2984-10537G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,4.437,\N,\N,OPA1
611921,3:193399322:C>T,NM_130837.2:c.2984-10530C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,3.273,\N,\N,OPA1
611922,3:193399323:G>C,NM_130837.2:c.2984-10529G>C,\N,\N,29/30,Benign,\N,intron_variant,0.507,0.0099,1KG_EAS_AF,OPA1
611923,3:193399325:A>G,NM_130837.2:c.2984-10527A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.195,\N,\N,OPA1
611924,3:193399346:G>A,NM_130837.2:c.2984-10506G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.4,\N,\N,OPA1
611925,3:193399355:T>C,NM_130837.2:c.2984-10497T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.194,0.001,1KG_EUR_AF,OPA1
611926,3:193399389:A>G,NM_130837.2:c.2984-10463A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.248,\N,\N,OPA1
611927,3:193399390:T>C,NM_130837.2:c.2984-10462T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.839,\N,\N,OPA1
611928,3:193399396:T>A,NM_130837.2:c.2984-10456T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,5.406,0.001,1KG_EAS_AF,OPA1
611929,3:193399398:T>C,NM_130837.2:c.2984-10454T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.455,\N,\N,OPA1
611930,3:193399506:T>A,NM_130837.2:c.2984-10346T>A,\N,\N,29/30,Benign,\N,intron_variant,2.955,0.0367,1KG_EAS_AF,OPA1
611931,3:193399544:G>A,NM_130837.2:c.2984-10308G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,3.959,0.001,1KG_EAS_AF,OPA1
611932,3:193399549:T>A,NM_130837.2:c.2984-10303T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.589,\N,\N,OPA1
611933,3:193399559:A>C,NM_130837.2:c.2984-10293A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.456,0.001,1KG_EUR_AF,OPA1
611934,3:193399572:C>CT,NM_130837.2:c.2984-10279dup,\N,\N,29/30,Benign,\N,intron_variant,5.134,0.1484,1KG_AMR_AF,OPA1
611935,3:193399601:T>G,NM_130837.2:c.2984-10251T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.307,\N,\N,OPA1
611936,3:193399615:G>A,NM_130837.2:c.2984-10237G>A,\N,\N,29/30,Benign,\N,intron_variant,2.783,0.0358,1KG_EUR_AF,OPA1
611937,3:193399651:GTCTC>G,NM_130837.2:c.2984-10196_2984-10193del,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611938,3:193399663:C>T,NM_130837.2:c.2984-10189C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,5.109,0.0029,1KG_AMR_AF,OPA1
611939,3:193399669:A>AG,NM_130837.2:c.2984-10181dup,\N,\N,29/30,Benign,\N,intron_variant,0.053,0.5696,1KG_AFR_AF,OPA1
611940,3:193399711:C>T,NM_130837.2:c.2984-10141C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,3.111,\N,\N,OPA1
611941,3:193399747:A>C,NM_130837.2:c.2984-10105A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.386,0.0029,1KG_AMR_AF,OPA1
611942,3:193399758:G>A,NM_130837.2:c.2984-10094G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.658,0.001,1KG_EAS_AF,OPA1
611943,3:193399801:G>C,NM_130837.2:c.2984-10051G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.129,\N,\N,OPA1
611944,3:193399806:G>A,NM_130837.2:c.2984-10046G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.281,\N,\N,OPA1
611945,3:193399809:A>G,NM_130837.2:c.2984-10043A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.26,\N,\N,OPA1
611946,3:193399830:A>G,NM_130837.2:c.2984-10022A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.439,\N,\N,OPA1
611947,3:193399851:G>A,NM_130837.2:c.2984-10001G>A,\N,\N,29/30,Benign,\N,intron_variant,0.849,0.0133,1KG_SAS_AF,OPA1
611948,3:193399863:G>A,NM_130837.2:c.2984-9989G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.769,\N,\N,OPA1
611949,3:193399871:C>A,NM_130837.2:c.2984-9981C>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.893,0.001,1KG_SAS_AF,OPA1
611950,3:193399874:G>A,NM_130837.2:c.2984-9978G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,3.505,0.0031,1KG_SAS_AF,OPA1
611951,3:193399908:C>T,NM_130837.2:c.2984-9944C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.099,\N,\N,OPA1
611952,3:193399917:A>C,NM_130837.2:c.2984-9935A>C,\N,\N,29/30,Benign,\N,intron_variant,0.135,0.0149,1KG_EAS_AF,OPA1
611953,3:193399940:A>T,NM_130837.2:c.2984-9912A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.663,0.002,1KG_EAS_AF,OPA1
611954,3:193399944:G>T,NM_130837.2:c.2984-9908G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.182,\N,\N,OPA1
611955,3:193399967:T>C,NM_130837.2:c.2984-9885T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,9.659,0.001,1KG_SAS_AF,OPA1
611956,3:193399987:A>G,NM_130837.2:c.2984-9865A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.146,\N,\N,OPA1
611957,3:193399992:T>C,NM_130837.2:c.2984-9860T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,6.104,0.001,1KG_SAS_AF,OPA1
611958,3:193400039:A>G,NM_130837.2:c.2984-9813A>G,\N,\N,29/30,Benign,\N,intron_variant,1.963,0.0061,1KG_SAS_AF,OPA1
611959,3:193400046:G>A,NM_130837.2:c.2984-9806G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.425,0.0023,1KG_AFR_AF,OPA1
611960,3:193400055:G>C,NM_130837.2:c.2984-9797G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.7,\N,\N,OPA1
611961,3:193400092:A>G,NM_130837.2:c.2984-9760A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.298,0.001,1KG_EAS_AF,OPA1
611962,3:193400096:T>TG,NM_130837.2:c.2984-9756_2984-9755insG,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611963,3:193400098:TG>T,NM_130837.2:c.2984-9752del,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611964,3:193400109:G>T,NM_130837.2:c.2984-9743G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.171,0.001,1KG_EAS_AF,OPA1
611965,3:193400124:A>G,NM_130837.2:c.2984-9728A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.134,\N,\N,OPA1
611966,3:193400146:G>C,NM_130837.2:c.2984-9706G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.04,\N,\N,OPA1
611967,3:193400154:C>T,NM_130837.2:c.2984-9698C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.574,0.0015,1KG_AFR_AF,OPA1
611968,3:193400171:G>A,NM_130837.2:c.2984-9681G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,5.146,0.001,1KG_EAS_AF,OPA1
611969,3:193400190:T>A,NM_130837.2:c.2984-9662T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,3.23,\N,\N,OPA1
611970,3:193400219:AC>A,NM_130837.2:c.2984-9632del,\N,\N,29/30,Benign,\N,intron_variant,1.119,0.0179,1KG_EAS_AF,OPA1
611971,3:193400248:A>G,NM_130837.2:c.2984-9604A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.151,0.003,1KG_EUR_AF,OPA1
611972,3:193400267:A>G,NM_130837.2:c.2984-9585A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.841,\N,\N,OPA1
611973,3:193400268:C>T,NM_130837.2:c.2984-9584C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.015,\N,\N,OPA1
611974,3:193400292:C>G,NM_130837.2:c.2984-9560C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.84,\N,\N,OPA1
611975,3:193400317:C>T,NM_130837.2:c.2984-9535C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.806,\N,\N,OPA1
611976,3:193400326:G>A,NM_130837.2:c.2984-9526G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.51,\N,\N,OPA1
611977,3:193400340:C>G,NM_130837.2:c.2984-9512C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.852,0.002,1KG_EAS_AF,OPA1
611978,3:193400366:A>G,NM_130837.2:c.2984-9486A>G,\N,\N,29/30,Benign,\N,intron_variant,1.046,0.0112,1KG_SAS_AF,OPA1
611979,3:193400401:A>AC,NM_130837.2:c.2984-9449dup,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611980,3:193400423:C>T,NM_130837.2:c.2984-9429C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.262,\N,\N,OPA1
611981,3:193400444:T>C,NM_130837.2:c.2984-9408T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.346,0.003,1KG_AFR_AF,OPA1
611982,3:193400531:C>A,NM_130837.2:c.2984-9321C>A,\N,\N,29/30,Unknown significance,\N,intron_variant,3.398,0.001,1KG_EUR_AF,OPA1
611983,3:193400558:C>A,NM_130837.2:c.2984-9294C>A,\N,\N,29/30,Unknown significance,\N,intron_variant,18.04,\N,\N,OPA1
611984,3:193400567:A>G,NM_130837.2:c.2984-9285A>G,\N,\N,29/30,Benign,\N,intron_variant,12.29,0.0115,1KG_AMR_AF,OPA1
611985,3:193400570:G>T,NM_130837.2:c.2984-9282G>T,\N,\N,29/30,Benign,\N,intron_variant,10.25,0.0197,1KG_AFR_AF,OPA1
611986,3:193400606:G>A,NM_130837.2:c.2984-9246G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.248,\N,\N,OPA1
611987,3:193400655:A>G,NM_130837.2:c.2984-9197A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,4.842,0.001,1KG_EUR_AF,OPA1
611988,3:193400670:C>T,NM_130837.2:c.2984-9182C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.87,0.0014,1KG_AMR_AF,OPA1
611989,3:193400687:A>G,NM_130837.2:c.2984-9165A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.148,\N,\N,OPA1
611990,3:193400701:A>T,NM_130837.2:c.2984-9151A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,3.01,0.0008,1KG_AFR_AF,OPA1
611991,3:193400708:T>C,NM_130837.2:c.2984-9144T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.791,\N,\N,OPA1
611992,3:193400760:T>G,NM_130837.2:c.2984-9092T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,4.016,0.0008,1KG_AFR_AF,OPA1
611993,3:193400774:G>GA,NM_130837.2:c.2984-9077dup,\N,\N,29/30,Unknown significance,\N,intron_variant,0.698,\N,\N,OPA1
611994,3:193400774:GA>G,NM_130837.2:c.2984-9077del,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
611995,3:193400775:AG>A,NM_130837.2:c.2984-9076del,\N,\N,29/30,Unknown significance,\N,intron_variant,0.075,\N,\N,OPA1
611996,3:193400776:G>A,NM_130837.2:c.2984-9076G>A,\N,\N,29/30,Benign,\N,intron_variant,0.222,0.6778,1KG_AFR_AF,OPA1
611997,3:193400862:G>A,NM_130837.2:c.2984-8990G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,3.147,0.002,1KG_EAS_AF,OPA1
611998,3:193400951:A>T,NM_130837.2:c.2984-8901A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.421,0.0014,1KG_AMR_AF,OPA1
611999,3:193400980:T>C,NM_130837.2:c.2984-8872T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,12.79,0.0008,1KG_AFR_AF,OPA1
612000,3:193400987:T>A,NM_130837.2:c.2984-8865T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.929,0.001,1KG_EAS_AF,OPA1
612001,3:193400993:A>T,NM_130837.2:c.2984-8859A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.387,\N,\N,OPA1
612002,3:193401021:A>G,NM_130837.2:c.2984-8831A>G,\N,\N,29/30,Benign,\N,intron_variant,0.914,0.7005,1KG_AFR_AF,OPA1
612003,3:193401054:TC>T,NM_130837.2:c.2984-8797del,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
612004,3:193401062:C>CT,NM_130837.2:c.2984-8776dup,\N,\N,29/30,Unknown significance,\N,intron_variant,4.523,\N,\N,OPA1
612005,3:193401062:CT>C,NM_130837.2:c.2984-8776del,\N,\N,29/30,Unknown significance,\N,intron_variant,5.872,\N,\N,OPA1
612006,3:193401078:G>T,NM_130837.2:c.2984-8774G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,4.979,\N,\N,OPA1
612007,3:193401185:C>T,NM_130837.2:c.2984-8667C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.469,0.001,1KG_EAS_AF,OPA1
612008,3:193401221:A>T,NM_130837.2:c.2984-8631A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.283,0.0008,1KG_AFR_AF,OPA1
612009,3:193401230:A>G,NM_130837.2:c.2984-8622A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.015,\N,\N,OPA1
612010,3:193401243:A>C,NM_130837.2:c.2984-8609A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.46,0.0014,1KG_AMR_AF,OPA1
612011,3:193401249:T>G,NM_130837.2:c.2984-8603T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,7.648,\N,\N,OPA1
612012,3:193401286:A>G,NM_130837.2:c.2984-8566A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.951,\N,\N,OPA1
612013,3:193401297:A>G,NM_130837.2:c.2984-8555A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,4.819,\N,\N,OPA1
612014,3:193401315:C>T,NM_130837.2:c.2984-8537C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,5.104,0.0014,1KG_AMR_AF,OPA1
612015,3:193401325:T>G,NM_130837.2:c.2984-8527T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.514,0.0029,1KG_AMR_AF,OPA1
612016,3:193401331:A>T,NM_130837.2:c.2984-8521A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.468,\N,\N,OPA1
612017,3:193401332:T>A,NM_130837.2:c.2984-8520T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,6.235,\N,\N,OPA1
612018,3:193401344:G>A,NM_130837.2:c.2984-8508G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.747,\N,\N,OPA1
612019,3:193401349:A>G,NM_130837.2:c.2984-8503A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.344,\N,\N,OPA1
612020,3:193401356:C>T,NM_130837.2:c.2984-8496C>T,\N,\N,29/30,Benign,\N,intron_variant,2.663,0.0234,1KG_AFR_AF,OPA1
612021,3:193401387:T>G,NM_130837.2:c.2984-8465T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,5.803,\N,\N,OPA1
612022,3:193401393:A>G,NM_130837.2:c.2984-8459A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,5.81,0.001,1KG_SAS_AF,OPA1
612023,3:193401409:G>A,NM_130837.2:c.2984-8443G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1,\N,\N,OPA1
612024,3:193401430:C>A,NM_130837.2:c.2984-8422C>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.706,\N,\N,OPA1
612025,3:193401433:G>C,NM_130837.2:c.2984-8419G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.223,0.0014,1KG_AMR_AF,OPA1
612026,3:193401437:A>G,NM_130837.2:c.2984-8415A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,5.257,\N,\N,OPA1
612027,3:193401452:A>G,NM_130837.2:c.2984-8400A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,6.009,\N,\N,OPA1
612028,3:193401468:C>T,NM_130837.2:c.2984-8384C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,8.074,0.003,1KG_AFR_AF,OPA1
612029,3:193401478:A>C,NM_130837.2:c.2984-8374A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,11.35,0.0008,1KG_AFR_AF,OPA1
612030,3:193401483:G>C,NM_130837.2:c.2984-8369G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,11.25,0.0008,1KG_AFR_AF,OPA1
612031,3:193401490:A>G,NM_130837.2:c.2984-8362A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,10.76,\N,\N,OPA1
612032,3:193401512:C>G,NM_130837.2:c.2984-8340C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.803,0.0008,1KG_AFR_AF,OPA1
612033,3:193401545:A>C,NM_130837.2:c.2984-8307A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.708,\N,\N,OPA1
612034,3:193401572:C>T,NM_130837.2:c.2984-8280C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.947,0.0014,1KG_AMR_AF,OPA1
612035,3:193401590:T>G,NM_130837.2:c.2984-8262T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,4.598,\N,\N,OPA1
612036,3:193401602:A>G,NM_130837.2:c.2984-8250A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.235,0.001,1KG_EAS_AF,OPA1
612037,3:193401609:T>G,NM_130837.2:c.2984-8243T>G,\N,\N,29/30,Benign,\N,intron_variant,2.809,0.0133,1KG_SAS_AF,OPA1
612038,3:193401626:C>T,NM_130837.2:c.2984-8226C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.074,0.001,1KG_EAS_AF,OPA1
612039,3:193401631:C>T,NM_130837.2:c.2984-8221C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.593,0.001,1KG_SAS_AF,OPA1
612040,3:193401632:G>A,NM_130837.2:c.2984-8220G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.491,0.0014,1KG_AMR_AF,OPA1
612041,3:193401632:G>T,NM_130837.2:c.2984-8220G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.186,\N,\N,OPA1
612042,3:193401657:T>C,NM_130837.2:c.2984-8195T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.471,0.0008,1KG_AFR_AF,OPA1
612043,3:193401660:C>G,NM_130837.2:c.2984-8192C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.519,0.001,1KG_EAS_AF,OPA1
612044,3:193401675:C>T,NM_130837.2:c.2984-8177C>T,\N,\N,29/30,Benign,\N,intron_variant,0.576,0.0333,1KG_AFR_AF,OPA1
612045,3:193401690:G>A,NM_130837.2:c.2984-8162G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.812,\N,\N,OPA1
612046,3:193401708:A>G,NM_130837.2:c.2984-8144A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.111,0.001,1KG_EAS_AF,OPA1
612047,3:193401722:T>C,NM_130837.2:c.2984-8130T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.245,\N,\N,OPA1
612048,3:193401737:A>G,NM_130837.2:c.2984-8115A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.567,0.001,1KG_EAS_AF,OPA1
612049,3:193401762:C>T,NM_130837.2:c.2984-8090C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.589,0.001,1KG_EAS_AF,OPA1
612050,3:193401771:G>A,NM_130837.2:c.2984-8081G>A,\N,\N,29/30,Benign,\N,intron_variant,1.963,0.008,1KG_EUR_AF,OPA1
612051,3:193401810:C>T,NM_130837.2:c.2984-8042C>T,\N,\N,29/30,Benign,\N,intron_variant,3.458,0.0358,1KG_SAS_AF,OPA1
612052,3:193401821:G>A,NM_130837.2:c.2984-8031G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.518,\N,\N,OPA1
612053,3:193401836:CA>C,NM_130837.2:c.2984-8014del,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
612054,3:193401854:G>T,NM_130837.2:c.2984-7998G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,11.92,\N,\N,OPA1
612055,3:193401860:G>T,NM_130837.2:c.2984-7992G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,8.5,\N,\N,OPA1
612056,3:193401874:C>T,NM_130837.2:c.2984-7978C>T,\N,\N,29/30,Benign,\N,intron_variant,1.304,0.428,1KG_AMR_AF,OPA1
612057,3:193401888:A>T,NM_130837.2:c.2984-7964A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.16,0.0014,1KG_AMR_AF,OPA1
612058,3:193401889:G>T,NM_130837.2:c.2984-7963G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.634,0.003,1KG_EAS_AF,OPA1
612059,3:193401924:G>A,NM_130837.2:c.2984-7928G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,9.011,0.001,1KG_EUR_AF,OPA1
612060,3:193401941:G>A,NM_130837.2:c.2984-7911G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,6.732,0.0008,1KG_AFR_AF,OPA1
612061,3:193401951:A>G,NM_130837.2:c.2984-7901A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.233,0.001,1KG_SAS_AF,OPA1
612062,3:193401975:T>C,NM_130837.2:c.2984-7877T>C,\N,\N,29/30,Benign,\N,intron_variant,3.779,0.0417,1KG_EUR_AF,OPA1
612063,3:193401994:C>T,NM_130837.2:c.2984-7858C>T,\N,\N,29/30,Benign,\N,intron_variant,0.432,0.0053,1KG_AFR_AF,OPA1
612064,3:193402000:A>G,NM_130837.2:c.2984-7852A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.613,0.0008,1KG_AFR_AF,OPA1
612065,3:193402003:A>G,NM_130837.2:c.2984-7849A>G,\N,\N,29/30,Benign,\N,intron_variant,2.058,0.4294,1KG_AMR_AF,OPA1
612066,3:193402006:C>G,NM_130837.2:c.2984-7846C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.299,\N,\N,OPA1
612067,3:193402006:C>T,NM_130837.2:c.2984-7846C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.737,0.0014,1KG_AMR_AF,OPA1
612068,3:193402008:T>C,NM_130837.2:c.2984-7844T>C,\N,\N,29/30,Benign,\N,intron_variant,1.841,0.5635,1KG_AFR_AF,OPA1
612069,3:193402020:A>T,NM_130837.2:c.2984-7832A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.008,0.0008,1KG_AFR_AF,OPA1
612070,3:193402043:C>A,NM_130837.2:c.2984-7809C>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.727,0.0014,1KG_AMR_AF,OPA1
612071,3:193402078:C>G,NM_130837.2:c.2984-7774C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.144,\N,\N,OPA1
612072,3:193402079:A>G,NM_130837.2:c.2984-7773A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.054,\N,\N,OPA1
612073,3:193402108:T>C,NM_130837.2:c.2984-7744T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.184,0.001,1KG_EUR_AF,OPA1
612074,3:193402117:T>A,NM_130837.2:c.2984-7735T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,3.004,\N,\N,OPA1
612075,3:193402235:C>CT,NM_130837.2:c.2984-7595dup,\N,\N,29/30,Unknown significance,\N,intron_variant,1.472,\N,\N,OPA1
612076,3:193402235:CTT>C,NM_130837.2:c.2984-7596_2984-7595del,\N,\N,29/30,Unknown significance,\N,intron_variant,1.778,\N,\N,OPA1
612077,3:193402235:CTTT>C,NM_130837.2:c.2984-7597_2984-7595del,\N,\N,29/30,Unknown significance,\N,intron_variant,1.909,\N,\N,OPA1
612078,3:193402253:T>G,NM_130837.2:c.2984-7599T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.466,\N,\N,OPA1
612079,3:193402266:G>A,NM_130837.2:c.2984-7586G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.034,0.001,1KG_SAS_AF,OPA1
612080,3:193402317:A>G,NM_130837.2:c.2984-7535A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.353,0.004,1KG_EUR_AF,OPA1
612081,3:193402326:G>A,NM_130837.2:c.2984-7526G>A,\N,\N,29/30,Benign,\N,intron_variant,0.154,0.0179,1KG_EAS_AF,OPA1
612082,3:193402380:C>T,NM_130837.2:c.2984-7472C>T,\N,\N,29/30,Benign,\N,intron_variant,1.565,0.0113,1KG_AFR_AF,OPA1
612083,3:193402384:C>T,NM_130837.2:c.2984-7468C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.134,0.0008,1KG_AFR_AF,OPA1
612084,3:193402386:C>A,NM_130837.2:c.2984-7466C>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.309,0.001,1KG_EAS_AF|1KG_SAS_AF,OPA1
612085,3:193402388:C>T,NM_130837.2:c.2984-7464C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.943,0.001,1KG_EUR_AF,OPA1
612086,3:193402401:G>A,NM_130837.2:c.2984-7451G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.179,0.0015,1KG_AFR_AF,OPA1
612087,3:193402412:G>A,NM_130837.2:c.2984-7440G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.902,\N,\N,OPA1
612088,3:193402487:G>A,NM_130837.2:c.2984-7365G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.336,0.001,1KG_EAS_AF,OPA1
612089,3:193402531:C>T,NM_130837.2:c.2984-7321C>T,\N,\N,29/30,Benign,\N,intron_variant,1.327,0.0403,1KG_AMR_AF,OPA1
612090,3:193402569:C>G,NM_130837.2:c.2984-7283C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.901,\N,\N,OPA1
612091,3:193402622:T>A,NM_130837.2:c.2984-7230T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,6.216,0.0008,1KG_AFR_AF,OPA1
612092,3:193402625:G>A,NM_130837.2:c.2984-7227G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.365,0.0008,1KG_AFR_AF,OPA1
612093,3:193402650:A>T,NM_130837.2:c.2984-7202A>T,\N,\N,29/30,Benign,\N,intron_variant,2.243,0.0174,1KG_SAS_AF,OPA1
612094,3:193402667:T>C,NM_130837.2:c.2984-7185T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.34,\N,\N,OPA1
612095,3:193402690:G>C,NM_130837.2:c.2984-7162G>C,\N,\N,29/30,Benign,\N,intron_variant,0.785,0.4289,1KG_AFR_AF,OPA1
612096,3:193402705:T>C,NM_130837.2:c.2984-7147T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.83,\N,\N,OPA1
612097,3:193402759:A>G,NM_130837.2:c.2984-7093A>G,\N,\N,29/30,Benign,\N,intron_variant,3.972,0.0113,1KG_AFR_AF,OPA1
612098,3:193402774:A>G,NM_130837.2:c.2984-7078A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.351,0.002,1KG_EAS_AF,OPA1
612099,3:193402790:T>A,NM_130837.2:c.2984-7062T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.862,\N,\N,OPA1
612100,3:193402818:C>T,NM_130837.2:c.2984-7034C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.204,\N,\N,OPA1
612101,3:193402828:C>T,NM_130837.2:c.2984-7024C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.404,0.001,1KG_SAS_AF,OPA1
612102,3:193402866:G>A,NM_130837.2:c.2984-6986G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.764,0.0008,1KG_AFR_AF,OPA1
612103,3:193402881:G>C,NM_130837.2:c.2984-6971G>C,\N,\N,29/30,Benign,\N,intron_variant,0.347,0.0133,1KG_SAS_AF,OPA1
612104,3:193402891:C>T,NM_130837.2:c.2984-6961C>T,\N,\N,29/30,Benign,\N,intron_variant,3.945,0.0069,1KG_EAS_AF,OPA1
612105,3:193402934:C>T,NM_130837.2:c.2984-6918C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,3.054,\N,\N,OPA1
612106,3:193402984:C>T,NM_130837.2:c.2984-6868C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.188,0.001,1KG_SAS_AF,OPA1
612107,3:193403015:C>T,NM_130837.2:c.2984-6837C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.521,0.0023,1KG_AFR_AF,OPA1
612108,3:193403016:G>A,NM_130837.2:c.2984-6836G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.24,\N,\N,OPA1
612109,3:193403019:A>T,NM_130837.2:c.2984-6833A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.667,\N,\N,OPA1
612110,3:193403023:G>A,NM_130837.2:c.2984-6829G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.154,0.001,1KG_SAS_AF,OPA1
612111,3:193403047:C>T,NM_130837.2:c.2984-6805C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.055,0.001,1KG_EAS_AF,OPA1
612112,3:193403048:G>A,NM_130837.2:c.2984-6804G>A,\N,\N,29/30,Benign,\N,intron_variant,1.419,0.4284,1KG_EUR_AF,OPA1
612113,3:193403063:C>G,NM_130837.2:c.2984-6789C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.847,0.0008,1KG_AFR_AF,OPA1
612114,3:193403069:C>T,NM_130837.2:c.2984-6783C>T,\N,\N,29/30,Benign,\N,intron_variant,1.664,0.005,1KG_EUR_AF,OPA1
612115,3:193403078:G>A,NM_130837.2:c.2984-6774G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.207,0.0029,1KG_AMR_AF,OPA1
612116,3:193403092:A>C,NM_130837.2:c.2984-6760A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,3.838,\N,\N,OPA1
612117,3:193403115:C>T,NM_130837.2:c.2984-6737C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,5.619,\N,\N,OPA1
612118,3:193403159:T>C,NM_130837.2:c.2984-6693T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.132,\N,\N,OPA1
612119,3:193403170:C>T,NM_130837.2:c.2984-6682C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,3.112,0.0014,1KG_AMR_AF,OPA1
612120,3:193403183:T>C,NM_130837.2:c.2984-6669T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.289,0.0008,1KG_AFR_AF,OPA1
612121,3:193403213:T>C,NM_130837.2:c.2984-6639T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.347,\N,\N,OPA1
612122,3:193403226:A>G,NM_130837.2:c.2984-6626A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.882,\N,\N,OPA1
612123,3:193403306:T>C,NM_130837.2:c.2984-6546T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,16.43,0.0008,1KG_AFR_AF,OPA1
612124,3:193403331:C>T,NM_130837.2:c.2984-6521C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,5.778,\N,\N,OPA1
612125,3:193403332:A>T,NM_130837.2:c.2984-6520A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,7.79,\N,\N,OPA1
612126,3:193403335:G>C,NM_130837.2:c.2984-6517G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,5.522,0.0014,1KG_AMR_AF,OPA1
612127,3:193403337:T>A,NM_130837.2:c.2984-6515T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,8.217,\N,\N,OPA1
612128,3:193403348:G>A,NM_130837.2:c.2984-6504G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.412,\N,\N,OPA1
612129,3:193403356:T>G,NM_130837.2:c.2984-6496T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,4.829,\N,\N,OPA1
612130,3:193403370:T>C,NM_130837.2:c.2984-6482T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.156,0.001,1KG_SAS_AF,OPA1
612131,3:193403380:T>C,NM_130837.2:c.2984-6472T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,4.741,\N,\N,OPA1
612132,3:193403531:C>T,NM_130837.2:c.2984-6321C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.273,0.001,1KG_SAS_AF,OPA1
612133,3:193403537:A>G,NM_130837.2:c.2984-6315A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,5.78,\N,\N,OPA1
612134,3:193403540:A>G,NM_130837.2:c.2984-6312A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,5.461,\N,\N,OPA1
612135,3:193403556:TAAAC>T,NM_130837.2:c.2984-6292_2984-6289del,\N,\N,29/30,Benign,\N,intron_variant,7.655,0.0179,1KG_EAS_AF,OPA1
612136,3:193403558:A>G,NM_130837.2:c.2984-6294A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.858,0.001,1KG_EUR_AF,OPA1
612137,3:193403584:A>G,NM_130837.2:c.2984-6268A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,4.51,\N,\N,OPA1
612138,3:193403616:T>C,NM_130837.2:c.2984-6236T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.312,\N,\N,OPA1
612139,3:193403658:T>G,NM_130837.2:c.2984-6194T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,6.574,\N,\N,OPA1
612140,3:193403664:C>T,NM_130837.2:c.2984-6188C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,5.256,0.0008,1KG_AFR_AF,OPA1
612141,3:193403698:C>T,NM_130837.2:c.2984-6154C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.526,0.0008,1KG_AFR_AF,OPA1
612142,3:193403700:G>A,NM_130837.2:c.2984-6152G>A,\N,\N,29/30,Benign,\N,intron_variant,2.995,0.09,1KG_AFR_AF,OPA1
612143,3:193403703:A>G,NM_130837.2:c.2984-6149A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.153,\N,\N,OPA1
612144,3:193403713:C>T,NM_130837.2:c.2984-6139C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.916,\N,\N,OPA1
612145,3:193403723:A>G,NM_130837.2:c.2984-6129A>G,\N,\N,29/30,Benign,\N,intron_variant,12.16,0.1362,1KG_AFR_AF,OPA1
612146,3:193403726:A>T,NM_130837.2:c.2984-6126A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,11.24,0.002,1KG_EAS_AF,OPA1
612147,3:193403780:A>G,NM_130837.2:c.2984-6072A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,4.315,\N,\N,OPA1
612148,3:193403781:T>A,NM_130837.2:c.2984-6071T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,5.624,\N,\N,OPA1
612149,3:193403794:T>C,NM_130837.2:c.2984-6058T>C,\N,\N,29/30,Benign,\N,intron_variant,2.503,0.1362,1KG_AFR_AF,OPA1
612150,3:193403834:T>TA,NM_130837.2:c.2984-6010dup,\N,\N,29/30,Unknown significance,\N,intron_variant,1.722,\N,\N,OPA1
612151,3:193403834:T>TAA,NM_130837.2:c.2984-6011_2984-6010dup,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
612152,3:193403842:A>T,NM_130837.2:c.2984-6010A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.466,0.0014,1KG_AMR_AF,OPA1
612153,3:193403856:T>C,NM_130837.2:c.2984-5996T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.892,\N,\N,OPA1
612154,3:193403860:T>A,NM_130837.2:c.2984-5992T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,5.249,\N,\N,OPA1
612155,3:193403885:A>G,NM_130837.2:c.2984-5967A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.899,0.002,1KG_EAS_AF,OPA1
612156,3:193403886:T>C,NM_130837.2:c.2984-5966T>C,\N,\N,29/30,Benign,\N,intron_variant,0.534,0.005,1KG_EUR_AF,OPA1
612157,3:193403896:G>T,NM_130837.2:c.2984-5956G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.344,0.001,1KG_SAS_AF,OPA1
612158,3:193403902:G>T,NM_130837.2:c.2984-5950G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.701,0.0029,1KG_AMR_AF,OPA1
612159,3:193403906:A>G,NM_130837.2:c.2984-5946A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.927,\N,\N,OPA1
612160,3:193404006:T>A,NM_130837.2:c.2984-5846T>A,\N,\N,29/30,Benign,\N,intron_variant,5.113,0.1362,1KG_AFR_AF,OPA1
612161,3:193404012:A>G,NM_130837.2:c.2984-5840A>G,\N,\N,29/30,Benign,\N,intron_variant,4.333,0.0113,1KG_AFR_AF,OPA1
612162,3:193404019:T>A,NM_130837.2:c.2984-5833T>A,\N,\N,29/30,Benign,\N,intron_variant,9.593,0.5719,1KG_AFR_AF,OPA1
612163,3:193404037:G>A,NM_130837.2:c.2984-5815G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,4.603,\N,\N,OPA1
612164,3:193404058:C>T,NM_130837.2:c.2984-5794C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.975,0.003,1KG_EAS_AF,OPA1
612165,3:193404103:T>C,NM_130837.2:c.2984-5749T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.056,0.001,1KG_EUR_AF,OPA1
612166,3:193404119:A>C,NM_130837.2:c.2984-5733A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.157,0.001,1KG_SAS_AF,OPA1
612167,3:193404148:C>CCTT,NM_130837.2:c.2984-5701_2984-5699dup,\N,\N,29/30,Benign,\N,intron_variant,12.55,0.4337,1KG_AMR_AF,OPA1
612168,3:193404148:C>T,NM_130837.2:c.2984-5704C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,12.2,\N,\N,OPA1
612169,3:193404149:C>CCTT,NM_130837.2:c.2984-5703_2984-5702insCTT,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
612170,3:193404150:T>TTTC,NM_130837.2:c.2984-5701_2984-5700insTCT,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
612171,3:193404151:T>C,NM_130837.2:c.2984-5701T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,9.421,0.0023,1KG_AFR_AF,OPA1
612172,3:193404167:G>A,NM_130837.2:c.2984-5685G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.281,\N,\N,OPA1
612173,3:193404174:G>C,NM_130837.2:c.2984-5678G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.309,\N,\N,OPA1
612174,3:193404234:A>C,NM_130837.2:c.2984-5618A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.793,\N,\N,OPA1
612175,3:193404249:A>G,NM_130837.2:c.2984-5603A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.65,\N,\N,OPA1
612176,3:193404268:A>G,NM_130837.2:c.2984-5584A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.284,\N,\N,OPA1
612177,3:193404271:T>G,NM_130837.2:c.2984-5581T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.498,\N,\N,OPA1
612178,3:193404291:G>A,NM_130837.2:c.2984-5561G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,5.561,\N,\N,OPA1
612179,3:193404314:G>C,NM_130837.2:c.2984-5538G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.129,0.001,1KG_EAS_AF,OPA1
612180,3:193404335:T>A,NM_130837.2:c.2984-5517T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,13.31,\N,\N,OPA1
612181,3:193404346:T>C,NM_130837.2:c.2984-5506T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.604,0.0014,1KG_AMR_AF,OPA1
612182,3:193404355:C>T,NM_130837.2:c.2984-5497C>T,\N,\N,29/30,Benign,\N,intron_variant,2.494,0.0082,1KG_SAS_AF,OPA1
612183,3:193404361:T>C,NM_130837.2:c.2984-5491T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,4.309,\N,\N,OPA1
612184,3:193404382:C>G,NM_130837.2:c.2984-5470C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.773,\N,\N,OPA1
612185,3:193404458:T>C,NM_130837.2:c.2984-5394T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.919,\N,\N,OPA1
612186,3:193404522:C>T,NM_130837.2:c.2984-5330C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.752,\N,\N,OPA1
612187,3:193404523:G>A,NM_130837.2:c.2984-5329G>A,\N,\N,29/30,Benign,\N,intron_variant,1.482,0.1362,1KG_AFR_AF,OPA1
612188,3:193404545:T>C,NM_130837.2:c.2984-5307T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.665,\N,\N,OPA1
612189,3:193404552:T>A,NM_130837.2:c.2984-5300T>A,\N,\N,29/30,Benign,\N,intron_variant,5.779,0.0113,1KG_AFR_AF,OPA1
612190,3:193404563:A>G,NM_130837.2:c.2984-5289A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,6.946,0.0008,1KG_AFR_AF,OPA1
612191,3:193404624:T>C,NM_130837.2:c.2984-5228T>C,\N,\N,29/30,Benign,\N,intron_variant,6.646,0.0189,1KG_AFR_AF,OPA1
612192,3:193404631:G>C,NM_130837.2:c.2984-5221G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,7.165,\N,\N,OPA1
612193,3:193404660:ATG>A,NM_130837.2:c.2984-5187_2984-5186del,\N,\N,29/30,Benign,\N,intron_variant,16.05,0.0367,1KG_EAS_AF,OPA1
612194,3:193404667:G>A,NM_130837.2:c.2984-5185G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,16.74,0.002,1KG_EAS_AF,OPA1
612195,3:193404680:A>AC,NM_130837.2:c.2984-5171dup,\N,\N,29/30,Benign,\N,intron_variant,13.56,0.0053,1KG_AFR_AF,OPA1
612196,3:193404742:A>T,NM_130837.2:c.2984-5110A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,13.92,0.0014,1KG_AMR_AF,OPA1
612197,3:193404797:GT>G,NM_130837.2:c.2984-5053del,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
612198,3:193404813:G>C,NM_130837.2:c.2984-5039G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,16.02,0.004,1KG_EUR_AF,OPA1
612199,3:193404890:G>A,NM_130837.2:c.2984-4962G>A,\N,\N,29/30,Benign,\N,intron_variant,18.11,0.006,1KG_EUR_AF,OPA1
612200,3:193404892:C>T,NM_130837.2:c.2984-4960C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,15.32,0.0031,1KG_SAS_AF,OPA1
612201,3:193404904:G>A,NM_130837.2:c.2984-4948G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,13.74,0.0014,1KG_AMR_AF,OPA1
612202,3:193404993:G>A,NM_130837.2:c.2984-4859G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,13.22,\N,\N,OPA1
612203,3:193405013:G>A,NM_130837.2:c.2984-4839G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,12.36,\N,\N,OPA1
612204,3:193405035:C>T,NM_130837.2:c.2984-4817C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,11.93,0.001,1KG_SAS_AF,OPA1
612205,3:193405061:A>G,NM_130837.2:c.2984-4791A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,14.38,0.0008,1KG_AFR_AF,OPA1
612206,3:193405063:A>G,NM_130837.2:c.2984-4789A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,13.9,\N,\N,OPA1
612207,3:193405081:A>G,NM_130837.2:c.2984-4771A>G,\N,\N,29/30,Benign,\N,intron_variant,12.46,0.0545,1KG_AFR_AF,OPA1
612208,3:193405105:A>G,NM_130837.2:c.2984-4747A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,12.83,0.001,1KG_EAS_AF,OPA1
612209,3:193405114:CT>C,NM_130837.2:c.2984-4734del,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
612210,3:193405121:G>T,NM_130837.2:c.2984-4731G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,14.01,0.001,1KG_SAS_AF,OPA1
612211,3:193405132:A>G,NM_130837.2:c.2984-4720A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,11.92,\N,\N,OPA1
612212,3:193405140:A>T,NM_130837.2:c.2984-4712A>T,\N,\N,29/30,Benign,\N,intron_variant,8.269,0.0133,1KG_SAS_AF,OPA1
612213,3:193405164:C>T,NM_130837.2:c.2984-4688C>T,\N,\N,29/30,Benign,\N,intron_variant,1.404,0.0179,1KG_EAS_AF,OPA1
612214,3:193405165:G>A,NM_130837.2:c.2984-4687G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.422,\N,\N,OPA1
612215,3:193405179:T>A,NM_130837.2:c.2984-4673T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.477,\N,\N,OPA1
612216,3:193405225:T>G,NM_130837.2:c.2984-4627T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,12.99,0.001,1KG_EUR_AF,OPA1
612217,3:193405265:G>A,NM_130837.2:c.2984-4587G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,6.756,0.0014,1KG_AMR_AF,OPA1
612218,3:193405281:A>G,NM_130837.2:c.2984-4571A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,7.349,0.0008,1KG_AFR_AF,OPA1
612219,3:193405295:A>G,NM_130837.2:c.2984-4557A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,6.178,0.003,1KG_EAS_AF,OPA1
612220,3:193405298:T>C,NM_130837.2:c.2984-4554T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.234,\N,\N,OPA1
612221,3:193405301:G>A,NM_130837.2:c.2984-4551G>A,\N,\N,29/30,Benign,\N,intron_variant,2.417,0.0875,1KG_EUR_AF,OPA1
612222,3:193405326:A>T,NM_130837.2:c.2984-4526A>T,\N,\N,29/30,Benign,\N,intron_variant,8.613,0.3204,1KG_EAS_AF,OPA1
612223,3:193405340:T>C,NM_130837.2:c.2984-4512T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,4.979,\N,\N,OPA1
612224,3:193405342:C>G,NM_130837.2:c.2984-4510C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2,0.001,1KG_SAS_AF,OPA1
612225,3:193405373:G>A,NM_130837.2:c.2984-4479G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.91,\N,\N,OPA1
612226,3:193405397:G>T,NM_130837.2:c.2984-4455G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.609,0.0031,1KG_SAS_AF,OPA1
612227,3:193405403:A>T,NM_130837.2:c.2984-4449A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,4.349,\N,\N,OPA1
612228,3:193405405:C>T,NM_130837.2:c.2984-4447C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.697,0.0029,1KG_AMR_AF,OPA1
612229,3:193405408:G>A,NM_130837.2:c.2984-4444G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.84,\N,\N,OPA1
612230,3:193405409:A>G,NM_130837.2:c.2984-4443A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.586,0.001,1KG_SAS_AF,OPA1
612231,3:193405432:A>T,NM_130837.2:c.2984-4420A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.23,0.0015,1KG_AFR_AF,OPA1
612232,3:193405435:G>A,NM_130837.2:c.2984-4417G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.627,0.001,1KG_EAS_AF,OPA1
612233,3:193405462:A>G,NM_130837.2:c.2984-4390A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,7.577,0.0031,1KG_SAS_AF,OPA1
612234,3:193405467:A>G,NM_130837.2:c.2984-4385A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,7.46,\N,\N,OPA1
612235,3:193405469:T>C,NM_130837.2:c.2984-4383T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,7.915,\N,\N,OPA1
612236,3:193405523:TACAG>T,NM_130837.2:c.2984-4325_2984-4322del,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
612237,3:193405527:G>C,NM_130837.2:c.2984-4325G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.867,0.0014,1KG_AMR_AF,OPA1
612238,3:193405534:T>C,NM_130837.2:c.2984-4318T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.994,\N,\N,OPA1
612239,3:193405546:A>G,NM_130837.2:c.2984-4306A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.765,\N,\N,OPA1
612240,3:193405571:A>G,NM_130837.2:c.2984-4281A>G,\N,\N,29/30,Benign,\N,intron_variant,11.99,0.1248,1KG_AFR_AF,OPA1
612241,3:193405578:A>C,NM_130837.2:c.2984-4274A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,11.62,0.001,1KG_EAS_AF,OPA1
612242,3:193405581:AT>A,NM_130837.2:c.2984-4269del,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
612243,3:193405614:A>C,NM_130837.2:c.2984-4238A>C,\N,\N,29/30,Benign,\N,intron_variant,0.22,0.0061,1KG_AFR_AF,OPA1
612244,3:193405628:G>A,NM_130837.2:c.2984-4224G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,5.577,0.0008,1KG_AFR_AF,OPA1
612245,3:193405635:A>G,NM_130837.2:c.2984-4217A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,4.03,0.0014,1KG_AMR_AF,OPA1
612246,3:193405656:A>G,NM_130837.2:c.2984-4196A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.686,\N,\N,OPA1
612247,3:193405708:A>G,NM_130837.2:c.2984-4144A>G,\N,\N,29/30,Benign,\N,intron_variant,2.467,0.0356,1KG_AFR_AF,OPA1
612248,3:193405718:A>AT,NM_130837.2:c.2984-4125dup,\N,\N,29/30,Unknown significance,\N,intron_variant,0.237,\N,\N,OPA1
612249,3:193405748:C>G,NM_130837.2:c.2984-4104C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.513,\N,\N,OPA1
612250,3:193405782:G>A,NM_130837.2:c.2984-4070G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.219,\N,\N,OPA1
612251,3:193405813:T>A,NM_130837.2:c.2984-4039T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,4.892,0.001,1KG_SAS_AF,OPA1
612252,3:193405830:G>T,NM_130837.2:c.2984-4022G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.991,0.002,1KG_EUR_AF,OPA1
612253,3:193405837:G>C,NM_130837.2:c.2984-4015G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.087,0.0029,1KG_AMR_AF,OPA1
612254,3:193405856:C>T,NM_130837.2:c.2984-3996C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.572,\N,\N,OPA1
612255,3:193405871:C>T,NM_130837.2:c.2984-3981C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,8.35,\N,\N,OPA1
612256,3:193405889:C>T,NM_130837.2:c.2984-3963C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.102,\N,\N,OPA1
612257,3:193405891:A>G,NM_130837.2:c.2984-3961A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.066,\N,\N,OPA1
612258,3:193405904:T>C,NM_130837.2:c.2984-3948T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.999,\N,\N,OPA1
612259,3:193405915:A>G,NM_130837.2:c.2984-3937A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.433,0.002,1KG_EUR_AF,OPA1
612260,3:193405954:C>T,NM_130837.2:c.2984-3898C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,7.934,0.004,1KG_EUR_AF,OPA1
612261,3:193405991:T>G,NM_130837.2:c.2984-3861T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,4.924,\N,\N,OPA1
612262,3:193405996:G>A,NM_130837.2:c.2984-3856G>A,\N,\N,29/30,Benign,\N,intron_variant,1.537,0.0634,1KG_AMR_AF,OPA1
612263,3:193405999:C>T,NM_130837.2:c.2984-3853C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,4.128,0.001,1KG_SAS_AF,OPA1
612264,3:193406032:ACT>A,NM_130837.2:c.2984-3817_2984-3816del,\N,\N,29/30,Benign,\N,intron_variant,5.941,0.0053,1KG_AFR_AF,OPA1
612265,3:193406043:T>C,NM_130837.2:c.2984-3809T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.36,\N,\N,OPA1
612266,3:193406066:G>C,NM_130837.2:c.2984-3786G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.057,\N,\N,OPA1
612267,3:193406073:T>C,NM_130837.2:c.2984-3779T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.568,\N,\N,OPA1
612268,3:193406079:G>A,NM_130837.2:c.2984-3773G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.872,\N,\N,OPA1
612269,3:193406088:C>A,NM_130837.2:c.2984-3764C>A,\N,\N,29/30,Unknown significance,\N,intron_variant,5.276,\N,\N,OPA1
612270,3:193406096:G>A,NM_130837.2:c.2984-3756G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.527,\N,\N,OPA1
612271,3:193406097:C>T,NM_130837.2:c.2984-3755C>T,\N,\N,29/30,Benign,\N,intron_variant,4.892,0.0219,1KG_AFR_AF,OPA1
612272,3:193406098:G>A,NM_130837.2:c.2984-3754G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.241,\N,\N,OPA1
612273,3:193406125:C>G,NM_130837.2:c.2984-3727C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.909,\N,\N,OPA1
612274,3:193406136:G>C,NM_130837.2:c.2984-3716G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,4.302,\N,\N,OPA1
612275,3:193406148:A>G,NM_130837.2:c.2984-3704A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.745,0.0014,1KG_AMR_AF,OPA1
612276,3:193406148:A>T,NM_130837.2:c.2984-3704A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.99,\N,\N,OPA1
612277,3:193406164:G>A,NM_130837.2:c.2984-3688G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,8.198,0.0029,1KG_AMR_AF,OPA1
612278,3:193406221:A>C,NM_130837.2:c.2984-3631A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.248,0.0045,1KG_AFR_AF,OPA1
612279,3:193406233:CTTTTCTTTTTTTTTTTTTTTTTTTTT>C,NM_130837.2:c.2984-3614_2984-3589del,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
612280,3:193406237:TC>T,NM_130837.2:c.2984-3614del,\N,\N,29/30,Unknown significance,\N,intron_variant,0.74,\N,\N,OPA1
612281,3:193406238:C>T,NM_130837.2:c.2984-3614C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.522,\N,\N,OPA1
612282,3:193406238:CTTTTTTTTTT>C,NM_130837.2:c.2984-3576_2984-3567del,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
612283,3:193406238:CTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT>C,NM_130837.2:c.2984-3602_2984-3567del,\N,\N,29/30,Unknown significance,\N,intron_variant,1.151,\N,\N,OPA1
612284,3:193406239:T>G,NM_130837.2:c.2984-3613T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.505,\N,\N,OPA1
612285,3:193406243:T>C,NM_130837.2:c.2984-3609T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.015,\N,\N,OPA1
612286,3:193406249:T>C,NM_130837.2:c.2984-3603T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.188,\N,\N,OPA1
612287,3:193406290:CAG>C,NM_130837.2:c.2984-3559_2984-3558del,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
612288,3:193406293:A>C,NM_130837.2:c.2984-3559A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.089,0.0008,1KG_AFR_AF,OPA1
612289,3:193406302:A>C,NM_130837.2:c.2984-3550A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.137,\N,\N,OPA1
612290,3:193406314:T>C,NM_130837.2:c.2984-3538T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.69,\N,\N,OPA1
612291,3:193406316:G>C,NM_130837.2:c.2984-3536G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.331,0.001,1KG_SAS_AF,OPA1
612292,3:193406342:C>G,NM_130837.2:c.2984-3510C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.953,\N,\N,OPA1
612293,3:193406353:G>A,NM_130837.2:c.2984-3499G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.724,\N,\N,OPA1
612294,3:193406360:G>A,NM_130837.2:c.2984-3492G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,3.272,0.0008,1KG_AFR_AF,OPA1
612295,3:193406410:A>T,NM_130837.2:c.2984-3442A>T,\N,\N,29/30,Benign,\N,intron_variant,7.838,0.0257,1KG_AFR_AF,OPA1
612296,3:193406423:T>G,NM_130837.2:c.2984-3429T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,10.85,\N,\N,OPA1
612297,3:193406429:T>C,NM_130837.2:c.2984-3423T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,10.28,0.001,1KG_EAS_AF,OPA1
612298,3:193406467:T>A,NM_130837.2:c.2984-3385T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,4.547,0.001,1KG_EUR_AF,OPA1
612299,3:193406503:T>C,NM_130837.2:c.2984-3349T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.468,0.0008,1KG_AFR_AF,OPA1
612300,3:193406504:C>T,NM_130837.2:c.2984-3348C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,4.538,\N,\N,OPA1
612301,3:193406508:C>T,NM_130837.2:c.2984-3344C>T,\N,\N,29/30,Benign,\N,intron_variant,5.344,0.005,1KG_EAS_AF,OPA1
612302,3:193406510:C>T,NM_130837.2:c.2984-3342C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.528,\N,\N,OPA1
612303,3:193406523:A>T,NM_130837.2:c.2984-3329A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.323,\N,\N,OPA1
612304,3:193406535:C>T,NM_130837.2:c.2984-3317C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,4.085,\N,\N,OPA1
612305,3:193406536:G>A,NM_130837.2:c.2984-3316G>A,\N,\N,29/30,Benign,\N,intron_variant,0.667,0.013,1KG_AMR_AF,OPA1
612306,3:193406581:G>A,NM_130837.2:c.2984-3271G>A,\N,\N,29/30,Benign,\N,intron_variant,3.88,0.0069,1KG_EAS_AF,OPA1
612307,3:193406601:T>A,NM_130837.2:c.2984-3251T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,4.725,\N,\N,OPA1
612308,3:193406605:G>A,NM_130837.2:c.2984-3247G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.137,\N,\N,OPA1
612309,3:193406607:C>CA,NM_130837.2:c.2984-3237dup,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
612310,3:193406614:A>T,NM_130837.2:c.2984-3238A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.282,\N,\N,OPA1
612311,3:193406705:G>T,NM_130837.2:c.2984-3147G>T,\N,\N,29/30,Benign,\N,intron_variant,1.329,0.0113,1KG_AFR_AF,OPA1
612312,3:193406708:G>A,NM_130837.2:c.2984-3144G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.053,0.001,1KG_SAS_AF,OPA1
612313,3:193406723:C>T,NM_130837.2:c.2984-3129C>T,\N,\N,29/30,Benign,\N,intron_variant,3.719,0.0174,1KG_SAS_AF,OPA1
612314,3:193406724:G>A,NM_130837.2:c.2984-3128G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.965,\N,\N,OPA1
612315,3:193406819:G>T,NM_130837.2:c.2984-3033G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.539,\N,\N,OPA1
612316,3:193406823:A>G,NM_130837.2:c.2984-3029A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.711,0.001,1KG_EUR_AF,OPA1
612317,3:193406860:A>G,NM_130837.2:c.2984-2992A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,4.077,0.0008,1KG_AFR_AF,OPA1
612318,3:193406893:A>C,NM_130837.2:c.2984-2959A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.734,0.003,1KG_EAS_AF,OPA1
612319,3:193406896:C>T,NM_130837.2:c.2984-2956C>T,\N,\N,29/30,Benign,\N,intron_variant,4.076,0.0257,1KG_AFR_AF,OPA1
612320,3:193406901:A>C,NM_130837.2:c.2984-2951A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.167,0.0015,1KG_AFR_AF,OPA1
612321,3:193406913:C>G,NM_130837.2:c.2984-2939C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,4.166,\N,\N,OPA1
612322,3:193406927:CAT>C,NM_130837.2:c.2984-2923_2984-2922del,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,0.003,1KG_AFR_AF,OPA1
612323,3:193406928:A>G,NM_130837.2:c.2984-2924A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,4.51,0.0008,1KG_AFR_AF,OPA1
612324,3:193406950:C>CT,NM_130837.2:c.2984-2900dup,\N,\N,29/30,Unknown significance,\N,intron_variant,5.912,0.0023,1KG_AFR_AF,OPA1
612325,3:193406966:T>TATC,NM_130837.2:c.2984-2882_2984-2880dup,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
612326,3:193406970:A>G,NM_130837.2:c.2984-2882A>G,\N,\N,29/30,Benign,\N,intron_variant,4.019,0.006,1KG_EUR_AF,OPA1
612327,3:193407045:T>G,NM_130837.2:c.2984-2807T>G,\N,\N,29/30,Benign,\N,intron_variant,4.137,0.0257,1KG_AFR_AF,OPA1
612328,3:193407075:C>T,NM_130837.2:c.2984-2777C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.847,0.0008,1KG_AFR_AF,OPA1
612329,3:193407094:G>C,NM_130837.2:c.2984-2758G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.267,0.001,1KG_EAS_AF,OPA1
612330,3:193407099:C>T,NM_130837.2:c.2984-2753C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.347,\N,\N,OPA1
612331,3:193407128:C>T,NM_130837.2:c.2984-2724C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.836,0.001,1KG_EAS_AF,OPA1
612332,3:193407138:A>G,NM_130837.2:c.2984-2714A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,4.766,0,1KG_ALL_AF|1KG_AFR_AF|1KG_AMR_AF|1KG_EAS_AF|1KG_EUR_AF|1KG_SAS_AF,OPA1
612333,3:193407168:G>A,NM_130837.2:c.2984-2684G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,4.271,0.001,1KG_EUR_AF,OPA1
612334,3:193407176:G>A,NM_130837.2:c.2984-2676G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,13.72,\N,\N,OPA1
612335,3:193407201:T>C,NM_130837.2:c.2984-2651T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.978,\N,\N,OPA1
612336,3:193407226:A>G,NM_130837.2:c.2984-2626A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.486,0.0008,1KG_AFR_AF,OPA1
612337,3:193407230:G>A,NM_130837.2:c.2984-2622G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.964,0.0015,1KG_AFR_AF,OPA1
612338,3:193407246:G>T,NM_130837.2:c.2984-2606G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.588,0.0008,1KG_AFR_AF,OPA1
612339,3:193407348:T>G,NM_130837.2:c.2984-2504T>G,\N,\N,29/30,Unknown significance,\N,intron_variant,5.55,0.001,1KG_EAS_AF,OPA1
612340,3:193407363:C>T,NM_130837.2:c.2984-2489C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,5.038,0.001,1KG_SAS_AF,OPA1
612341,3:193407373:G>C,NM_130837.2:c.2984-2479G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.013,0.001,1KG_EAS_AF,OPA1
612342,3:193407377:G>T,NM_130837.2:c.2984-2475G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.011,0.0031,1KG_SAS_AF,OPA1
612343,3:193407399:A>G,NM_130837.2:c.2984-2453A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.164,0.0029,1KG_AMR_AF,OPA1
612344,3:193407447:C>T,NM_130837.2:c.2984-2405C>T,\N,\N,29/30,Benign,\N,intron_variant,4.554,0.4274,1KG_EUR_AF,OPA1
612345,3:193407454:C>T,NM_130837.2:c.2984-2398C>T,\N,\N,29/30,Benign,\N,intron_variant,3.896,0.0461,1KG_AFR_AF,OPA1
612346,3:193407466:A>C,NM_130837.2:c.2984-2386A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.353,\N,\N,OPA1
612347,3:193407482:G>A,NM_130837.2:c.2984-2370G>A,\N,\N,29/30,Benign,\N,intron_variant,3.024,0.0953,1KG_AFR_AF,OPA1
612348,3:193407508:G>T,NM_130837.2:c.2984-2344G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.701,\N,\N,OPA1
612349,3:193407554:A>G,NM_130837.2:c.2984-2298A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.263,\N,\N,OPA1
612350,3:193407580:A>G,NM_130837.2:c.2984-2272A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,4.075,0.0015,1KG_AFR_AF,OPA1
612351,3:193407622:T>C,NM_130837.2:c.2984-2230T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,3.296,0.001,1KG_EAS_AF,OPA1
612352,3:193407631:G>A,NM_130837.2:c.2984-2221G>A,\N,\N,29/30,Benign,\N,intron_variant,5.123,0.0188,1KG_EAS_AF,OPA1
612353,3:193407650:G>A,NM_130837.2:c.2984-2202G>A,\N,\N,29/30,Benign,\N,intron_variant,1.347,0.4308,1KG_AMR_AF,OPA1
612354,3:193407676:G>A,NM_130837.2:c.2984-2176G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.761,0.0008,1KG_AFR_AF,OPA1
612355,3:193407703:C>A,NM_130837.2:c.2984-2149C>A,\N,\N,29/30,Benign,\N,intron_variant,3.579,0.4314,1KG_EUR_AF,OPA1
612356,3:193407717:A>C,NM_130837.2:c.2984-2135A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.859,0.0008,1KG_AFR_AF,OPA1
612357,3:193407731:T>C,NM_130837.2:c.2984-2121T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.572,0.003,1KG_EAS_AF,OPA1
612358,3:193407793:T>TA,NM_130837.2:c.2984-2058dup,\N,\N,29/30,Unknown significance,\N,intron_variant,13.93,\N,\N,OPA1
612359,3:193407803:GA>G,NM_130837.2:c.2984-2035del,\N,\N,29/30,Benign,\N,intron_variant,14.91,0.2277,1KG_AMR_AF,OPA1
612360,3:193407803:GAA>G,NM_130837.2:c.2984-2036_2984-2035del,\N,\N,29/30,Unknown significance,\N,intron_variant,15.93,\N,\N,OPA1
612361,3:193407804:A>G,NM_130837.2:c.2984-2048A>G,\N,\N,29/30,Benign,\N,intron_variant,14.49,0.0257,1KG_AFR_AF,OPA1
612362,3:193407816:A>G,NM_130837.2:c.2984-2036A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,13.46,0.001,1KG_EUR_AF,OPA1
612363,3:193407846:T>C,NM_130837.2:c.2984-2006T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.722,\N,\N,OPA1
612364,3:193407862:C>T,NM_130837.2:c.2984-1990C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,5.437,\N,\N,OPA1
612365,3:193407889:A>G,NM_130837.2:c.2984-1963A>G,\N,\N,29/30,Benign,\N,intron_variant,4.493,0.5711,1KG_AFR_AF,OPA1
612366,3:193407920:A>G,NM_130837.2:c.2984-1932A>G,\N,\N,29/30,Benign,\N,intron_variant,2.603,0.0189,1KG_AFR_AF,OPA1
612367,3:193407930:A>G,NM_130837.2:c.2984-1922A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,4.891,0.001,1KG_EUR_AF,OPA1
612368,3:193407959:C>T,NM_130837.2:c.2984-1893C>T,\N,\N,29/30,Benign,\N,intron_variant,1.445,0.0072,1KG_SAS_AF,OPA1
612369,3:193407969:A>G,NM_130837.2:c.2984-1883A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.349,0.002,1KG_EAS_AF,OPA1
612370,3:193407979:A>AT,NM_130837.2:c.2984-1862dup,\N,\N,29/30,Benign,\N,intron_variant,0.238,0.5477,1KG_AFR_AF,OPA1
612371,3:193407979:AT>A,NM_130837.2:c.2984-1862del,\N,\N,29/30,Benign,\N,intron_variant,0.548,0.3135,1KG_EAS_AF,OPA1
612372,3:193407992:A>T,NM_130837.2:c.2984-1860A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.072,\N,\N,OPA1
612373,3:193407999:C>G,NM_130837.2:c.2984-1853C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.785,\N,\N,OPA1
612374,3:193408002:G>T,NM_130837.2:c.2984-1850G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.442,\N,\N,OPA1
612375,3:193408014:A>G,NM_130837.2:c.2984-1838A>G,\N,\N,29/30,Benign,\N,intron_variant,5.334,0.0083,1KG_AFR_AF,OPA1
612376,3:193408053:A>G,NM_130837.2:c.2984-1799A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.105,\N,\N,OPA1
612377,3:193408070:A>T,NM_130837.2:c.2984-1782A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.801,0.002,1KG_EAS_AF,OPA1
612378,3:193408090:ACTC>A,NM_130837.2:c.2984-1760_2984-1758del,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
612379,3:193408091:CT>C,NM_130837.2:c.2984-1760del,\N,\N,29/30,Unknown significance,\N,intron_variant,3.843,\N,\N,OPA1
612380,3:193408092:T>TCC,NM_130837.2:c.2984-1753_2984-1752dup,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
612381,3:193408092:TC>T,NM_130837.2:c.2984-1752del,\N,\N,29/30,Unknown significance,\N,intron_variant,0.529,\N,\N,OPA1
612382,3:193408092:TCCC>T,NM_130837.2:c.2984-1754_2984-1752del,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
612383,3:193408098:CCCA>C,NM_130837.2:c.2984-1751_2984-1749del,\N,\N,29/30,Benign,\N,intron_variant,0.986,0.7495,1KG_SAS_AF,OPA1
612384,3:193408098:CCCACCCCA>C,NM_130837.2:c.2984-1751_2984-1744del,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
612385,3:193408101:A>C,NM_130837.2:c.2984-1751A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.935,\N,\N,OPA1
612386,3:193408103:C>G,NM_130837.2:c.2984-1749C>G,\N,\N,29/30,Benign,\N,intron_variant,0.446,0.0179,1KG_EAS_AF,OPA1
612387,3:193408128:A>G,NM_130837.2:c.2984-1724A>G,\N,\N,29/30,Benign,\N,intron_variant,3.439,0.1354,1KG_AFR_AF,OPA1
612388,3:193408129:T>C,NM_130837.2:c.2984-1723T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.765,0.001,1KG_EAS_AF,OPA1
612389,3:193408172:A>T,NM_130837.2:c.2984-1680A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.418,0.002,1KG_SAS_AF,OPA1
612390,3:193408199:C>G,NM_130837.2:c.2984-1653C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.12,0.001,1KG_SAS_AF,OPA1
612391,3:193408246:C>CGA,NM_130837.2:c.2984-1606_2984-1605insGA,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
612392,3:193408270:T>G,NM_130837.2:c.2984-1582T>G,\N,\N,29/30,Benign,\N,intron_variant,0.471,0.0068,1KG_AFR_AF,OPA1
612393,3:193408302:T>C,NM_130837.2:c.2984-1550T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.204,\N,\N,OPA1
612394,3:193408348:C>T,NM_130837.2:c.2984-1504C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.268,0.002,1KG_SAS_AF,OPA1
612395,3:193408352:C>T,NM_130837.2:c.2984-1500C>T,\N,\N,29/30,Benign,\N,intron_variant,4.386,0.1225,1KG_AFR_AF,OPA1
612396,3:193408370:T>C,NM_130837.2:c.2984-1482T>C,\N,\N,29/30,Benign,\N,intron_variant,2.533,0.0235,1KG_SAS_AF,OPA1
612397,3:193408392:A>G,NM_130837.2:c.2984-1460A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.199,\N,\N,OPA1
612398,3:193408419:A>G,NM_130837.2:c.2984-1433A>G,\N,\N,29/30,Benign,\N,intron_variant,3.551,0.4284,1KG_SAS_AF,OPA1
612399,3:193408451:T>C,NM_130837.2:c.2984-1401T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.873,\N,\N,OPA1
612400,3:193408461:G>A,NM_130837.2:c.2984-1391G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.005,\N,\N,OPA1
612401,3:193408520:G>A,NM_130837.2:c.2984-1332G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,7.109,0.001,1KG_SAS_AF,OPA1
612402,3:193408521:A>T,NM_130837.2:c.2984-1331A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.841,0.0029,1KG_AMR_AF,OPA1
612403,3:193408545:A>T,NM_130837.2:c.2984-1307A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,3.404,\N,\N,OPA1
612404,3:193408685:T>C,NM_130837.2:c.2984-1167T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,10.66,\N,\N,OPA1
612405,3:193408716:TAGG>T,NM_130837.2:c.2984-1132_2984-1130del,\N,\N,29/30,Unknown significance,\N,intron_variant,9.889,\N,\N,OPA1
612406,3:193408818:CAA>C,NM_130837.2:c.2984-1032_2984-1031del,\N,\N,29/30,Benign,\N,intron_variant,6.959,0.1362,1KG_AFR_AF,OPA1
612407,3:193408847:T>C,NM_130837.2:c.2984-1005T>C,\N,\N,29/30,Benign,\N,intron_variant,2.551,0.5106,1KG_AFR_AF,OPA1
612408,3:193408855:A>G,NM_130837.2:c.2984-997A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.133,0.002,1KG_EAS_AF,OPA1
612409,3:193408861:T>C,NM_130837.2:c.2984-991T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.173,0.001,1KG_EUR_AF,OPA1
612410,3:193408870:C>A,NM_130837.2:c.2984-982C>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.822,0.0014,1KG_AMR_AF,OPA1
612411,3:193408881:G>A,NM_130837.2:c.2984-971G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.006,\N,\N,OPA1
612412,3:193408881:G>T,NM_130837.2:c.2984-971G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.002,\N,\N,OPA1
612413,3:193408901:G>A,NM_130837.2:c.2984-951G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.286,\N,\N,OPA1
612414,3:193408915:C>T,NM_130837.2:c.2984-937C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.837,0.0023,1KG_AFR_AF,OPA1
612415,3:193408916:G>A,NM_130837.2:c.2984-936G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.819,0.002,1KG_SAS_AF,OPA1
612416,3:193408951:A>C,NM_130837.2:c.2984-901A>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.401,\N,\N,OPA1
612417,3:193408963:C>T,NM_130837.2:c.2984-889C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.616,\N,\N,OPA1
612418,3:193408976:C>T,NM_130837.2:c.2984-876C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.92,\N,\N,OPA1
612419,3:193408977:G>A,NM_130837.2:c.2984-875G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.681,\N,\N,OPA1
612420,3:193408987:G>A,NM_130837.2:c.2984-865G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.327,\N,\N,OPA1
612421,3:193408988:C>T,NM_130837.2:c.2984-864C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.667,\N,\N,OPA1
612422,3:193409000:A>G,NM_130837.2:c.2984-852A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,3.439,0.0014,1KG_AMR_AF,OPA1
612423,3:193409003:C>T,NM_130837.2:c.2984-849C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,4.167,0.001,1KG_EUR_AF,OPA1
612424,3:193409004:C>T,NM_130837.2:c.2984-848C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,4.305,\N,\N,OPA1
612425,3:193409021:A>G,NM_130837.2:c.2984-831A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.891,\N,\N,OPA1
612426,3:193409021:ATAAAG>A,NM_130837.2:c.2984-828_2984-824del,\N,\N,29/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
612427,3:193409036:C>A,NM_130837.2:c.2984-816C>A,\N,\N,29/30,Unknown significance,\N,intron_variant,1.095,\N,\N,OPA1
612428,3:193409048:T>C,NM_130837.2:c.2984-804T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,3.953,\N,\N,OPA1
612429,3:193409058:G>C,NM_130837.2:c.2984-794G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.877,\N,\N,OPA1
612430,3:193409075:G>C,NM_130837.2:c.2984-777G>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.471,\N,\N,OPA1
612431,3:193409094:A>G,NM_130837.2:c.2984-758A>G,\N,\N,29/30,Benign,\N,intron_variant,3.737,0.8783,1KG_SAS_AF,OPA1
612432,3:193409107:A>G,NM_130837.2:c.2984-745A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.263,0.001,1KG_EAS_AF,OPA1
612433,3:193409109:T>A,NM_130837.2:c.2984-743T>A,\N,\N,29/30,Unknown significance,\N,intron_variant,7.082,\N,\N,OPA1
612434,3:193409138:A>G,NM_130837.2:c.2984-714A>G,\N,\N,29/30,Benign,\N,intron_variant,6.128,0.8497,1KG_SAS_AF,OPA1
612435,3:193409156:T>C,NM_130837.2:c.2984-696T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.381,0.001,1KG_EUR_AF,OPA1
612436,3:193409178:A>G,NM_130837.2:c.2984-674A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,4.297,\N,\N,OPA1
612437,3:193409204:G>A,NM_130837.2:c.2984-648G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,3.295,0.001,1KG_EUR_AF,OPA1
612438,3:193409211:G>A,NM_130837.2:c.2984-641G>A,\N,\N,29/30,Benign,\N,intron_variant,3.6,0.053,1KG_AFR_AF,OPA1
612439,3:193409252:T>C,NM_130837.2:c.2984-600T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.006,0.004,1KG_EUR_AF,OPA1
612440,3:193409268:AC>A,NM_130837.2:c.2984-582del,\N,\N,29/30,Benign,\N,intron_variant,0.292,0.1316,1KG_AFR_AF,OPA1
612441,3:193409274:G>A,NM_130837.2:c.2984-578G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.112,0.001,1KG_EAS_AF,OPA1
612442,3:193409288:T>C,NM_130837.2:c.2984-564T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,1.244,0.0015,1KG_AFR_AF,OPA1
612443,3:193409289:G>A,NM_130837.2:c.2984-563G>A,\N,\N,29/30,Benign,\N,intron_variant,0.128,0.0106,1KG_AFR_AF,OPA1
612444,3:193409338:T>C,NM_130837.2:c.2984-514T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,0.609,0.0014,1KG_AMR_AF,OPA1
612445,3:193409353:A>G,NM_130837.2:c.2984-499A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,2.368,0.001,1KG_SAS_AF,OPA1
612446,3:193409359:A>G,NM_130837.2:c.2984-493A>G,\N,\N,29/30,Benign,\N,intron_variant,0.929,0.0091,1KG_AFR_AF,OPA1
612447,3:193409362:T>C,NM_130837.2:c.2984-490T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,2.812,0.0008,1KG_AFR_AF,OPA1
612448,3:193409384:C>G,NM_130837.2:c.2984-468C>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.559,\N,\N,OPA1
612449,3:193409402:CTTTATA>C,NM_130837.2:c.2984-445_2984-440del,\N,\N,29/30,Unknown significance,\N,intron_variant,7.076,\N,\N,OPA1
612450,3:193409444:A>G,NM_130837.2:c.2984-408A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,0.172,0.001,1KG_SAS_AF,OPA1
612451,3:193409467:G>A,NM_130837.2:c.2984-385G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,2.474,\N,\N,OPA1
612452,3:193409488:C>T,NM_130837.2:c.2984-364C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,1.526,\N,\N,OPA1
612453,3:193409536:G>A,NM_130837.2:c.2984-316G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,4.192,0.001,1KG_SAS_AF,OPA1
612454,3:193409573:A>T,NM_130837.2:c.2984-279A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.634,\N,\N,OPA1
612455,3:193409574:C>T,NM_130837.2:c.2984-278C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,2.373,0.0008,1KG_AFR_AF,OPA1
612456,3:193409580:C>CTT,NM_130837.2:c.2984-271_2984-270dup,\N,\N,29/30,Benign,\N,intron_variant,2.696,0.0102,1KG_SAS_AF,OPA1
612457,3:193409602:G>A,NM_130837.2:c.2984-250G>A,\N,\N,29/30,Benign,\N,intron_variant,5.92,0.1324,1KG_AFR_AF,OPA1
612458,3:193409614:G>T,NM_130837.2:c.2984-238G>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.526,0.0008,1KG_AFR_AF,OPA1
612459,3:193409634:A>G,NM_130837.2:c.2984-218A>G,\N,\N,29/30,Unknown significance,\N,intron_variant,1.451,0.001,1KG_SAS_AF,OPA1
612460,3:193409669:A>T,NM_130837.2:c.2984-183A>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.109,0.0029,1KG_AMR_AF,OPA1
612461,3:193409681:C>T,NM_130837.2:c.2984-171C>T,\N,\N,29/30,Unknown significance,\N,intron_variant,0.236,0.0008,1KG_AFR_AF,OPA1
612462,3:193409718:A>T,NM_130837.2:c.2984-134A>T,\N,\N,29/30,Benign,\N,intron_variant,3.902,0.0068,1KG_AFR_AF,OPA1
612463,3:193409726:T>C,NM_130837.2:c.2984-126T>C,\N,\N,29/30,Benign,\N,intron_variant,1.857,0.1541,1KG_EUR_AF,OPA1
612464,3:193409728:G>A,NM_130837.2:c.2984-124G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.471,\N,\N,OPA1
612465,3:193409750:T>C,NM_130837.2:c.2984-102T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,3.706,0.001,1KG_EUR_AF,OPA1
612466,3:193409754:G>A,NM_130837.2:c.2984-98G>A,\N,\N,29/30,Unknown significance,\N,intron_variant,0.491,\N,\N,OPA1
612467,3:193409769:T>C,NM_130837.2:c.2984-83T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,11.95,0.002,1KG_SAS_AF,OPA1
612468,3:193409805:T>C,NM_130837.2:c.2984-47T>C,\N,\N,29/30,Unknown significance,\N,intron_variant,6.597,0.000127421,EVS_EA_AF,OPA1
612469,3:193409848:A>G,NM_130837.2:c.2984-4A>G,\N,\N,29/30,Benign,\N,splice_region_variant&intron_variant,5.243,0.015873,EXAC_EAS_AF,OPA1
612470,3:193409849:CAGAG>C,NM_130837.2:c.2984-1_2986del,\N,30/31,29/30,Pathogenic,Optic atrophy 1 plus,splice_acceptor_variant&coding_sequence_variant,35,\N,\N,OPA1
612471,3:193409850:A>C,NM_130837.2:c.2984-2A>C,\N,\N,29/30,Pathogenic,Optic atrophy 1,splice_acceptor_variant,23.4,\N,\N,OPA1
612472,3:193409855:AAGTT>A,NM_130837.2:c.2990_2993del,NP_570850.2:p.Val997GlufsTer25,30/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,35,\N,\N,OPA1
612473,3:193409857:GT>G,NM_130837.2:c.2991del,NP_570850.2:p.Arg998GlufsTer25,30/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,35,\N,\N,OPA1
612474,3:193409859:TAGAGAAATTC>GGATGCTCCA,NM_130837.2:c.2991_3001delinsGGATGCTCCA,NP_570850.2:p.Arg998AspfsTer25,30/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,\N,\N,\N,OPA1
612475,3:193409875:A>C,NM_130837.2:c.3007A>C,NP_570850.2:p.Lys1003Gln,30/31,\N,Unknown significance,\N,missense_variant,23.9,0.000115473,EXAC_SAS_AF,OPA1
612476,3:193409878:C>G,NM_130833.2:c.2848C>G,NP_570846.1:p.Leu950Val,28/29,\N,Unknown significance,\N,missense_variant,29.1,\N,\N,OPA1
612477,3:193409879:T>C,NM_130837.2:c.3011T>C,NP_570850.2:p.Leu1004Pro,30/31,\N,Pathogenic,Optic atrophy 1,missense_variant,26.5,\N,\N,OPA1
612478,3:193409879:T>G,NM_130837.2:c.3011T>G,NP_570850.2:p.Leu1004Arg,30/31,\N,Pathogenic,Optic atrophy,missense_variant,27.4,\N,\N,OPA1
612479,3:193409880:TGA>T,NM_130837.2:c.3013_3014del,NP_570850.2:p.Asp1005CysfsTer4,30/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,36,\N,\N,OPA1
612480,3:193409882:AT>A,NM_130837.2:c.3015del,NP_570850.2:p.Asp1005GlufsTer18,30/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,34,\N,\N,OPA1
612481,3:193409885:C>G,NM_130837.2:c.3017C>G,NP_570850.2:p.Ala1006Gly,30/31,\N,Unknown significance,\N,missense_variant,24.3,0.0031,1KG_SAS_AF,OPA1
612482,3:193409885:C>CT,NM_130837.2:c.3020dup,NP_570850.2:p.Ile1008HisfsTer2,30/31,\N,Pathogenic,Optic atrophy 1,frameshift_variant,35,\N,\N,OPA1
612483,3:193409891:T>C,NM_130837.2:c.3023T>C,NP_570850.2:p.Ile1008Thr,30/31,\N,Unknown significance,\N,missense_variant,18.14,0.000295683,EXAC_AFR_AF,OPA1
612484,3:193409895:A>C,NM_130837.2:c.3027A>C,NP_570850.2:p.Glu1009Asp,30/31,\N,Benign,\N,missense_variant,21.7,0.0058,1KG_AMR_AF,OPA1
612485,3:193409910:GA>G,NM_130837.2:c.3045del,NP_570850.2:p.Lys1015AsnfsTer8,30/31,\N,Unknown significance,\N,frameshift_variant,\N,\N,\N,OPA1
612486,3:193409916:A>C,NM_130837.2:c.3048A>C,NP_570850.2:p.Ter1016TyrextTer13,30/31,\N,Pathogenic,Optic atrophy 1,stop_lost,15.18,\N,\N,OPA1
612487,3:193409916:A>G,NM_130837.2:c.3048A>G,NP_570850.2:p.Ter1016=,30/31,\N,Unknown significance,\N,stop_retained_variant,8.934,0.001,1KG_EAS_AF,OPA1
612488,3:193409918:TTAAG>T,NM_130837.2:c.*4_*5+2del,\N,30/31,30/30,Unknown significance,\N,splice_donor_variant&3_prime_UTR_variant,26.7,0.000234247,EXAC_SAS_AF,OPA1
612489,3:193409918:T>C,NM_130837.2:c.*2T>C,\N,30/31,\N,Unknown significance,\N,3_prime_UTR_variant,8.704,0.0019084,EXAC_EAS_AF,OPA1
612490,3:193409945:A>G,NM_130837.2:c.*5+24A>G,\N,\N,30/30,Unknown significance,\N,intron_variant,2.253,0.000232666,EVS_AA_AF,OPA1
612491,3:193409949:G>A,NM_130837.2:c.*5+28G>A,\N,\N,30/30,Unknown significance,\N,intron_variant,2.218,0.0023,1KG_AFR_AF,OPA1
612492,3:193409955:A>T,NM_130837.2:c.*5+34A>T,\N,\N,30/30,Unknown significance,\N,intron_variant,1.75,\N,\N,OPA1
612493,3:193409961:T>C,NM_130837.2:c.*5+40T>C,\N,\N,30/30,Unknown significance,\N,intron_variant,2.367,0.000120831,EXAC_SAS_AF,OPA1
612494,3:193409965:A>G,NM_130837.2:c.*5+44A>G,\N,\N,30/30,Unknown significance,\N,intron_variant,5.506,0.000120831,EXAC_SAS_AF,OPA1
612495,3:193409974:T>C,NM_130837.2:c.*5+53T>C,\N,\N,30/30,Unknown significance,\N,intron_variant,3.165,\N,\N,OPA1
612496,3:193409976:T>C,NM_130837.2:c.*5+55T>C,\N,\N,30/30,Unknown significance,\N,intron_variant,0.836,0.001,1KG_EUR_AF,OPA1
612497,3:193409983:TA>T,NM_130837.2:c.*5+63del,\N,\N,30/30,Unknown significance,\N,intron_variant,\N,\N,\N,OPA1
612498,3:193410001:C>T,NM_130837.2:c.*5+80C>T,\N,\N,30/30,Unknown significance,\N,intron_variant,0.382,0.001,1KG_SAS_AF,OPA1
612499,3:193410053:G>A,NM_130837.2:c.*5+132G>A,\N,\N,30/30,Unknown significance,\N,intron_variant,6.642,\N,\N,OPA1
612500,3:193410084:G>A,NM_130837.2:c.*5+163G>A,\N,\N,30/30,Unknown significance,\N,intron_variant,2.411,0.0015,1KG_AFR_AF,OPA1
612501,3:193410102:A>G,NM_130837.2:c.*5+181A>G,\N,\N,30/30,Unknown significance,\N,intron_variant,8.445,\N,\N,OPA1
612502,3:193410189:T>C,NM_130837.2:c.*5+268T>C,\N,\N,30/30,Unknown significance,\N,intron_variant,2.233,\N,\N,OPA1
612503,3:193410217:G>C,NM_130837.2:c.*5+296G>C,\N,\N,30/30,Unknown significance,\N,intron_variant,0.544,0.0008,1KG_AFR_AF,OPA1
612504,3:193410257:A>G,NM_130837.2:c.*5+336A>G,\N,\N,30/30,Unknown significance,\N,intron_variant,3.772,0.001,1KG_EAS_AF,OPA1
612505,3:193410259:A>G,NM_130837.2:c.*5+338A>G,\N,\N,30/30,Unknown significance,\N,intron_variant,1.722,\N,\N,OPA1
612506,3:193410279:T>C,NM_130837.2:c.*5+358T>C,\N,\N,30/30,Unknown significance,\N,intron_variant,2.601,\N,\N,OPA1
612507,3:193410310:G>C,NM_130837.2:c.*5+389G>C,\N,\N,30/30,Unknown significance,\N,intron_variant,1.813,0.004,1KG_EAS_AF,OPA1
612508,3:193410314:G>T,NM_130837.2:c.*5+393G>T,\N,\N,30/30,Unknown significance,\N,intron_variant,2.118,0.001,1KG_SAS_AF,OPA1
612509,3:193410321:T>A,NM_130837.2:c.*5+400T>A,\N,\N,30/30,Unknown significance,\N,intron_variant,4.967,\N,\N,OPA1
612510,3:193410338:G>A,NM_130837.2:c.*5+417G>A,\N,\N,30/30,Unknown significance,\N,intron_variant,2.888,\N,\N,OPA1
612511,3:193410355:CTT>C,NM_130837.2:c.*5+437_*5+438del,\N,\N,30/30,Unknown significance,\N,intron_variant,13.32,0.004,1KG_EUR_AF,OPA1
612512,3:193410380:G>A,NM_130837.2:c.*5+459G>A,\N,\N,30/30,Unknown significance,\N,intron_variant,10.76,\N,\N,OPA1
612513,3:193410396:A>G,NM_130837.2:c.*5+475A>G,\N,\N,30/30,Unknown significance,\N,intron_variant,12.77,0.001,1KG_SAS_AF,OPA1
612514,3:193410404:A>G,NM_130837.2:c.*5+483A>G,\N,\N,30/30,Benign,\N,intron_variant,10.6,0.0091,1KG_AFR_AF,OPA1
612515,3:193410419:T>C,NM_130837.2:c.*5+498T>C,\N,\N,30/30,Unknown significance,\N,intron_variant,5.758,0.001,1KG_EUR_AF|1KG_SAS_AF,OPA1
612516,3:193410420:A>G,NM_130837.2:c.*5+499A>G,\N,\N,30/30,Unknown significance,\N,intron_variant,3.682,0.0014,1KG_AMR_AF,OPA1
612517,3:193410440:T>A,NM_130837.2:c.*5+519T>A,\N,\N,30/30,Unknown significance,\N,intron_variant,5.565,\N,\N,OPA1
612518,3:193410499:C>T,NM_130837.2:c.*5+578C>T,\N,\N,30/30,Unknown significance,\N,intron_variant,4.858,0.001,1KG_SAS_AF,OPA1
612519,3:193410514:A>G,NM_130837.2:c.*5+593A>G,\N,\N,30/30,Unknown significance,\N,intron_variant,16.35,0.003,1KG_EUR_AF,OPA1
612520,3:193410537:G>A,NM_130837.2:c.*5+616G>A,\N,\N,30/30,Benign,\N,intron_variant,1.553,0.4256,1KG_EAS_AF,OPA1
612521,3:193410555:C>G,NM_130837.2:c.*5+634C>G,\N,\N,30/30,Unknown significance,\N,intron_variant,1.045,0.003,1KG_AFR_AF,OPA1
612522,3:193410571:G>A,NM_130837.2:c.*5+650G>A,\N,\N,30/30,Unknown significance,\N,intron_variant,1.445,0.001,1KG_SAS_AF,OPA1
612523,3:193410576:C>T,NM_130837.2:c.*5+655C>T,\N,\N,30/30,Benign,\N,intron_variant,0.547,0.3876,1KG_AMR_AF,OPA1
612524,3:193410577:G>A,NM_130837.2:c.*5+656G>A,\N,\N,30/30,Unknown significance,\N,intron_variant,1.119,0.0015,1KG_AFR_AF,OPA1
612525,3:193410674:GA>G,NM_130837.2:c.*5+755del,\N,\N,30/30,Benign,\N,intron_variant,0.01,0.0184,1KG_SAS_AF,OPA1
612526,3:193410701:A>G,NM_130837.2:c.*5+780A>G,\N,\N,30/30,Unknown significance,\N,intron_variant,14.54,\N,\N,OPA1
612527,3:193410749:G>A,NM_130837.2:c.*5+828G>A,\N,\N,30/30,Unknown significance,\N,intron_variant,1.67,0.001,1KG_EAS_AF|1KG_SAS_AF,OPA1
612528,3:193410758:G>A,NM_130837.2:c.*5+837G>A,\N,\N,30/30,Benign,\N,intron_variant,8.576,0.0091,1KG_AFR_AF,OPA1
612529,3:193410764:A>C,NM_130837.2:c.*5+843A>C,\N,\N,30/30,Benign,\N,intron_variant,7.279,0.0129,1KG_EAS_AF,OPA1
612530,3:193410803:G>A,NM_130837.2:c.*5+882G>A,\N,\N,30/30,Benign,\N,intron_variant,1.695,0.0265,1KG_AFR_AF,OPA1
612531,3:193410835:T>A,NM_130837.2:c.*5+914T>A,\N,\N,30/30,Unknown significance,\N,intron_variant,4.69,\N,\N,OPA1
612532,3:193410897:T>C,NM_130837.2:c.*5+976T>C,\N,\N,30/30,Unknown significance,\N,intron_variant,4.078,\N,\N,OPA1
612533,3:193410898:A>G,NM_130837.2:c.*5+977A>G,\N,\N,30/30,Unknown significance,\N,intron_variant,5.863,\N,\N,OPA1
612534,3:193410911:G>T,NM_130837.2:c.*5+990G>T,\N,\N,30/30,Benign,\N,intron_variant,0.021,0.0058,1KG_AMR_AF,OPA1
612535,3:193410923:GC>G,NM_130837.2:c.*5+1003del,\N,\N,30/30,Benign,\N,intron_variant,1.694,0.0567,1KG_AFR_AF,OPA1
612536,3:193410926:A>G,NM_130837.2:c.*5+1005A>G,\N,\N,30/30,Unknown significance,\N,intron_variant,3.186,0.0031,1KG_SAS_AF,OPA1
612537,3:193410927:C>T,NM_130837.2:c.*5+1006C>T,\N,\N,30/30,Unknown significance,\N,intron_variant,3.097,0.0008,1KG_AFR_AF,OPA1
612538,3:193410932:G>A,NM_130837.2:c.*5+1011G>A,\N,\N,30/30,Unknown significance,\N,intron_variant,3.861,\N,\N,OPA1
612539,3:193410932:G>T,NM_130837.2:c.*5+1011G>T,\N,\N,30/30,Unknown significance,\N,intron_variant,1.959,\N,\N,OPA1
612540,3:193410933:G>T,NM_130837.2:c.*5+1012G>T,\N,\N,30/30,Unknown significance,\N,intron_variant,5.21,\N,\N,OPA1
612541,3:193410954:G>A,NM_130837.2:c.*5+1033G>A,\N,\N,30/30,Unknown significance,\N,intron_variant,4.991,\N,\N,OPA1
612542,3:193410957:C>G,NM_130837.2:c.*5+1036C>G,\N,\N,30/30,Unknown significance,\N,intron_variant,2.15,0.0023,1KG_AFR_AF,OPA1
612543,3:193410957:C>T,NM_130837.2:c.*5+1036C>T,\N,\N,30/30,Unknown significance,\N,intron_variant,3.166,0.002,1KG_EAS_AF,OPA1
612544,3:193410972:C>T,NM_130837.2:c.*5+1051C>T,\N,\N,30/30,Benign,\N,intron_variant,2.978,0.0212,1KG_AFR_AF,OPA1
612545,3:193410975:CT>C,NM_130837.2:c.*5+1057del,\N,\N,30/30,Unknown significance,\N,intron_variant,4.931,0.003,1KG_EAS_AF,OPA1
612546,3:193410980:C>T,NM_130837.2:c.*5+1059C>T,\N,\N,30/30,Unknown significance,\N,intron_variant,3.151,\N,\N,OPA1
612547,3:193410997:T>C,NM_130837.2:c.*5+1076T>C,\N,\N,30/30,Unknown significance,\N,intron_variant,3.777,\N,\N,OPA1
612548,3:193411034:T>C,NM_130837.2:c.*5+1113T>C,\N,\N,30/30,Unknown significance,\N,intron_variant,2.857,0.0008,1KG_AFR_AF,OPA1
612549,3:193411054:T>C,NM_130837.2:c.*5+1133T>C,\N,\N,30/30,Unknown significance,\N,intron_variant,3.219,0.0008,1KG_AFR_AF,OPA1
612550,3:193411142:A>T,NM_130837.2:c.*5+1221A>T,\N,\N,30/30,Unknown significance,\N,intron_variant,7.609,0.002,1KG_SAS_AF,OPA1
612551,3:193411156:C>T,NM_130837.2:c.*5+1235C>T,\N,\N,30/30,Unknown significance,\N,intron_variant,1.01,0.0014,1KG_AMR_AF,OPA1
612552,3:193411190:A>T,NM_130837.2:c.*6-1205A>T,\N,\N,30/30,Unknown significance,\N,intron_variant,1.982,\N,\N,OPA1
612553,3:193411193:C>T,NM_130837.2:c.*6-1202C>T,\N,\N,30/30,Unknown significance,\N,intron_variant,3.431,\N,\N,OPA1
612554,3:193411197:G>T,NM_130837.2:c.*6-1198G>T,\N,\N,30/30,Benign,\N,intron_variant,0.79,0.6587,1KG_EAS_AF,OPA1
612555,3:193411199:C>T,NM_130837.2:c.*6-1196C>T,\N,\N,30/30,Unknown significance,\N,intron_variant,0.215,0.003,1KG_EAS_AF,OPA1
612556,3:193411200:G>A,NM_130837.2:c.*6-1195G>A,\N,\N,30/30,Benign,\N,intron_variant,1.453,0.3194,1KG_EAS_AF,OPA1
612557,3:193411216:G>A,NM_130837.2:c.*6-1179G>A,\N,\N,30/30,Unknown significance,\N,intron_variant,8.427,0.002,1KG_EUR_AF,OPA1
612558,3:193411231:C>A,NM_130837.2:c.*6-1164C>A,\N,\N,30/30,Unknown significance,\N,intron_variant,9.401,0.001,1KG_EAS_AF,OPA1
612559,3:193411248:G>A,NM_130837.2:c.*6-1147G>A,\N,\N,30/30,Unknown significance,\N,intron_variant,6.914,\N,\N,OPA1
612560,3:193411257:C>T,NM_130837.2:c.*6-1138C>T,\N,\N,30/30,Unknown significance,\N,intron_variant,2.434,\N,\N,OPA1
612561,3:193411322:G>T,NM_130837.2:c.*6-1073G>T,\N,\N,30/30,Benign,\N,intron_variant,0.733,0.0865,1KG_EUR_AF,OPA1
612562,3:193411326:G>C,NM_130837.2:c.*6-1069G>C,\N,\N,30/30,Benign,\N,intron_variant,0.592,0.0179,1KG_EAS_AF,OPA1
612563,3:193411344:A>C,NM_130837.2:c.*6-1051A>C,\N,\N,30/30,Unknown significance,\N,intron_variant,1.311,0.0014,1KG_AMR_AF,OPA1
612564,3:193411361:A>G,NM_130837.2:c.*6-1034A>G,\N,\N,30/30,Benign,\N,intron_variant,2.835,0.0184,1KG_SAS_AF,OPA1
612565,3:193411398:C>A,NM_130837.2:c.*6-997C>A,\N,\N,30/30,Benign,\N,intron_variant,3.402,0.0184,1KG_SAS_AF,OPA1
612566,3:193411407:C>T,NM_130837.2:c.*6-988C>T,\N,\N,30/30,Unknown significance,\N,intron_variant,0.106,\N,\N,OPA1
612567,3:193411415:C>T,NM_130837.2:c.*6-980C>T,\N,\N,30/30,Unknown significance,\N,intron_variant,3.425,\N,\N,OPA1
612568,3:193411416:G>A,NM_130837.2:c.*6-979G>A,\N,\N,30/30,Benign,\N,intron_variant,0.944,0.0091,1KG_AFR_AF,OPA1
612569,3:193411431:A>G,NM_130837.2:c.*6-964A>G,\N,\N,30/30,Unknown significance,\N,intron_variant,7.393,0.0015,1KG_AFR_AF,OPA1
612570,3:193411439:G>A,NM_130837.2:c.*6-956G>A,\N,\N,30/30,Unknown significance,\N,intron_variant,7.815,0.001,1KG_SAS_AF,OPA1
612571,3:193411444:G>A,NM_130837.2:c.*6-951G>A,\N,\N,30/30,Unknown significance,\N,intron_variant,4.288,\N,\N,OPA1
612572,3:193411494:T>C,NM_130837.2:c.*6-901T>C,\N,\N,30/30,Unknown significance,\N,intron_variant,0.721,0.0015,1KG_AFR_AF,OPA1
612573,3:193411532:T>C,NM_130837.2:c.*6-863T>C,\N,\N,30/30,Unknown significance,\N,intron_variant,4.142,0.003,1KG_AFR_AF,OPA1
612574,3:193411551:T>C,NM_130837.2:c.*6-844T>C,\N,\N,30/30,Unknown significance,\N,intron_variant,0.309,\N,\N,OPA1
612575,3:193411569:T>C,NM_130837.2:c.*6-826T>C,\N,\N,30/30,Unknown significance,\N,intron_variant,0.935,\N,\N,OPA1
612576,3:193411579:A>T,NM_130837.2:c.*6-816A>T,\N,\N,30/30,Unknown significance,\N,intron_variant,2.695,0.0008,1KG_AFR_AF,OPA1
612577,3:193411583:A>G,NM_130837.2:c.*6-812A>G,\N,\N,30/30,Unknown significance,\N,intron_variant,1.219,0.002,1KG_SAS_AF,OPA1
612578,3:193411583:AGT>A,NM_130837.2:c.*6-809_*6-808del,\N,\N,30/30,Unknown significance,\N,intron_variant,\N,0.003,1KG_EAS_AF|1KG_EUR_AF,OPA1
612579,3:193411584:G>T,NM_130837.2:c.*6-811G>T,\N,\N,30/30,Unknown significance,\N,intron_variant,1.634,\N,\N,OPA1
612580,3:193411589:A>C,NM_130837.2:c.*6-806A>C,\N,\N,30/30,Benign,\N,intron_variant,0.467,0.3862,1KG_AMR_AF,OPA1
612581,3:193411598:C>A,NM_130837.2:c.*6-797C>A,\N,\N,30/30,Unknown significance,\N,intron_variant,3.686,0.001,1KG_SAS_AF,OPA1
612582,3:193411608:G>A,NM_130837.2:c.*6-787G>A,\N,\N,30/30,Unknown significance,\N,intron_variant,4.363,\N,\N,OPA1
612583,3:193411621:A>G,NM_130837.2:c.*6-774A>G,\N,\N,30/30,Unknown significance,\N,intron_variant,2.242,0.001,1KG_EUR_AF,OPA1
612584,3:193411629:C>T,NM_130837.2:c.*6-766C>T,\N,\N,30/30,Unknown significance,\N,intron_variant,6.25,0.0008,1KG_AFR_AF,OPA1
612585,3:193411652:C>T,NM_130837.2:c.*6-743C>T,\N,\N,30/30,Unknown significance,\N,intron_variant,5.44,0.0008,1KG_AFR_AF,OPA1
612586,3:193411691:A>G,NM_130837.2:c.*6-704A>G,\N,\N,30/30,Unknown significance,\N,intron_variant,3.096,0.0029,1KG_AMR_AF,OPA1
612587,3:193411705:T>C,NM_130837.2:c.*6-690T>C,\N,\N,30/30,Benign,\N,intron_variant,1.266,0.8436,1KG_SAS_AF,OPA1
612588,3:193411723:C>T,NM_130837.2:c.*6-672C>T,\N,\N,30/30,Benign,\N,intron_variant,5.872,0.379,1KG_EAS_AF,OPA1
612589,3:193411733:T>C,NM_130837.2:c.*6-662T>C,\N,\N,30/30,Unknown significance,\N,intron_variant,0.053,0.001,1KG_EAS_AF,OPA1
612590,3:193411755:C>T,NM_130837.2:c.*6-640C>T,\N,\N,30/30,Unknown significance,\N,intron_variant,6.058,\N,\N,OPA1
612591,3:193411756:G>GT,NM_130837.2:c.*6-637dup,\N,\N,30/30,Benign,\N,intron_variant,4.182,0.008,1KG_EUR_AF,OPA1
612592,3:193411778:C>T,NM_130837.2:c.*6-617C>T,\N,\N,30/30,Unknown significance,\N,intron_variant,8.736,\N,\N,OPA1
612593,3:193411875:G>A,NM_130837.2:c.*6-520G>A,\N,\N,30/30,Benign,\N,intron_variant,3.851,0.6715,1KG_AMR_AF,OPA1
612594,3:193411930:T>A,NM_130837.2:c.*6-465T>A,\N,\N,30/30,Unknown significance,\N,intron_variant,7.792,0.001,1KG_EAS_AF,OPA1
612595,3:193411959:T>G,NM_130837.2:c.*6-436T>G,\N,\N,30/30,Benign,\N,intron_variant,3.749,0.0371,1KG_AFR_AF,OPA1
612596,3:193412010:T>G,NM_130837.2:c.*6-385T>G,\N,\N,30/30,Unknown significance,\N,intron_variant,8.039,0.001,1KG_EAS_AF,OPA1
612597,3:193412016:A>C,NM_130837.2:c.*6-379A>C,\N,\N,30/30,Unknown significance,\N,intron_variant,2.694,0.001,1KG_EUR_AF,OPA1
612598,3:193412071:A>G,NM_130837.2:c.*6-324A>G,\N,\N,30/30,Unknown significance,\N,intron_variant,4.782,0.0008,1KG_AFR_AF,OPA1
612599,3:193412077:A>T,NM_130837.2:c.*6-318A>T,\N,\N,30/30,Unknown significance,\N,intron_variant,1.522,0.0008,1KG_AFR_AF,OPA1
612600,3:193412102:A>G,NM_130837.2:c.*6-293A>G,\N,\N,30/30,Unknown significance,\N,intron_variant,0.667,0.001,1KG_EAS_AF,OPA1
612601,3:193412129:A>C,NM_130837.2:c.*6-266A>C,\N,\N,30/30,Benign,\N,intron_variant,0.078,0.0058,1KG_AMR_AF,OPA1
612602,3:193412151:A>G,NM_130837.2:c.*6-244A>G,\N,\N,30/30,Unknown significance,\N,intron_variant,2.621,0.0008,1KG_AFR_AF,OPA1
612603,3:193412168:A>G,NM_130837.2:c.*6-227A>G,\N,\N,30/30,Unknown significance,\N,intron_variant,3.83,\N,\N,OPA1
612604,3:193412183:A>G,NM_130837.2:c.*6-212A>G,\N,\N,30/30,Unknown significance,\N,intron_variant,6.366,\N,\N,OPA1
612605,3:193412187:A>G,NM_130837.2:c.*6-208A>G,\N,\N,30/30,Unknown significance,\N,intron_variant,12.01,\N,\N,OPA1
612606,3:193412239:G>T,NM_130837.2:c.*6-156G>T,\N,\N,30/30,Unknown significance,\N,intron_variant,0.463,0.001,1KG_SAS_AF,OPA1
612607,3:193412247:G>A,NM_130837.2:c.*6-148G>A,\N,\N,30/30,Unknown significance,\N,intron_variant,5.96,0.0029,1KG_AMR_AF,OPA1
612608,3:193412286:A>C,NM_130837.2:c.*6-109A>C,\N,\N,30/30,Unknown significance,\N,intron_variant,1.623,0.002,1KG_SAS_AF,OPA1
612609,3:193412290:G>A,NM_130837.2:c.*6-105G>A,\N,\N,30/30,Unknown significance,\N,intron_variant,2.904,\N,\N,OPA1
612610,3:193412338:G>A,NM_130837.2:c.*6-57G>A,\N,\N,30/30,Unknown significance,\N,intron_variant,8.419,\N,\N,OPA1
612611,3:193412430:G>A,NM_130837.2:c.*41G>A,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,9.061,0.001,1KG_EAS_AF,OPA1
612612,3:193412445:C>T,NM_130837.2:c.*56C>T,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,2.706,\N,\N,OPA1
612613,3:193412513:A>G,NM_130837.2:c.*124A>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,7.398,\N,\N,OPA1
612614,3:193412596:A>G,NM_130837.2:c.*207A>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,8.269,\N,\N,OPA1
612615,3:193412609:A>G,NM_130837.2:c.*220A>G,\N,31/31,\N,Benign,\N,3_prime_UTR_variant,3.87,0.0174,1KG_AFR_AF,OPA1
612616,3:193412617:A>G,NM_130837.2:c.*228A>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,5.742,0.002,1KG_EAS_AF,OPA1
612617,3:193412630:A>G,NM_130837.2:c.*241A>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,4.366,\N,\N,OPA1
612618,3:193412636:G>C,NM_130837.2:c.*247G>C,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,3.178,\N,\N,OPA1
612619,3:193412642:G>T,NM_130837.2:c.*253G>T,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,8.178,\N,\N,OPA1
612620,3:193412669:G>A,NM_130837.2:c.*280G>A,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,14.35,0.0008,1KG_AFR_AF,OPA1
612621,3:193412672:A>G,NM_130837.2:c.*283A>G,\N,31/31,\N,Benign,\N,3_prime_UTR_variant,13.79,0.696,1KG_AMR_AF,OPA1
612622,3:193412680:T>C,NM_130837.2:c.*291T>C,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,8.923,0.0014,1KG_AMR_AF,OPA1
612623,3:193412681:C>G,NM_130837.2:c.*292C>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,8.128,\N,\N,OPA1
612624,3:193412717:T>G,NM_130837.2:c.*328T>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,3.543,0.0029,1KG_AMR_AF,OPA1
612625,3:193412765:A>G,NM_130837.2:c.*376A>G,\N,31/31,\N,Benign,\N,3_prime_UTR_variant,12.09,0.0179,1KG_EAS_AF,OPA1
612626,3:193412792:T>C,NM_130837.2:c.*403T>C,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,4.133,\N,\N,OPA1
612627,3:193412801:T>C,NM_130837.2:c.*412T>C,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,4.919,0.001,1KG_SAS_AF,OPA1
612628,3:193412816:A>G,NM_130837.2:c.*427A>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,7.531,0.0008,1KG_AFR_AF,OPA1
612629,3:193412816:A>T,NM_130837.2:c.*427A>T,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,7.845,\N,\N,OPA1
612630,3:193412821:A>G,NM_130837.2:c.*432A>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,11.64,\N,\N,OPA1
612631,3:193412862:G>A,NM_130837.2:c.*473G>A,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,5.965,\N,\N,OPA1
612632,3:193412891:C>T,NM_130837.2:c.*502C>T,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,4.296,0.0023,1KG_AFR_AF,OPA1
612633,3:193412936:A>C,NM_130837.2:c.*547A>C,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,1.574,0.004,1KG_EAS_AF,OPA1
612634,3:193412949:T>C,NM_130837.2:c.*560T>C,\N,31/31,\N,Benign,\N,3_prime_UTR_variant,2.111,0.9603,1KG_EAS_AF,OPA1
612635,3:193412976:G>A,NM_130837.2:c.*587G>A,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,2.248,\N,\N,OPA1
612636,3:193413011:C>T,NM_130837.2:c.*622C>T,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,6.575,\N,\N,OPA1
612637,3:193413012:G>A,NM_130837.2:c.*623G>A,\N,31/31,\N,Benign,\N,3_prime_UTR_variant,1.531,0.0348,1KG_AFR_AF,OPA1
612638,3:193413083:C>A,NM_130837.2:c.*694C>A,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,6.314,0.0014,1KG_AMR_AF,OPA1
612639,3:193413085:A>G,NM_130837.2:c.*696A>G,\N,31/31,\N,Benign,\N,3_prime_UTR_variant,3.401,0.0053,1KG_AFR_AF,OPA1
612640,3:193413132:G>C,NM_130837.2:c.*743G>C,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,13.32,\N,\N,OPA1
612641,3:193413177:G>A,NM_130837.2:c.*788G>A,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,8.324,0.0008,1KG_AFR_AF,OPA1
612642,3:193413250:C>T,NM_130837.2:c.*861C>T,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,10.49,\N,\N,OPA1
612643,3:193413252:A>G,NM_130837.2:c.*863A>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,7.693,0.0014,1KG_AMR_AF,OPA1
612644,3:193413270:G>T,NM_130837.2:c.*881G>T,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,7.959,0.002,1KG_SAS_AF,OPA1
612645,3:193413386:A>G,NM_130837.2:c.*997A>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,3.513,0.001,1KG_EAS_AF,OPA1
612646,3:193413420:A>T,NM_130837.2:c.*1031A>T,\N,31/31,\N,Benign,\N,3_prime_UTR_variant,2.264,0.0242,1KG_AFR_AF,OPA1
612647,3:193413428:A>G,NM_130837.2:c.*1039A>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,3.639,\N,\N,OPA1
612648,3:193413467:C>T,NM_130837.2:c.*1078C>T,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,5.909,\N,\N,OPA1
612649,3:193413476:C>T,NM_130837.2:c.*1087C>T,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,6.395,\N,\N,OPA1
612650,3:193413502:C>T,NM_130837.2:c.*1113C>T,\N,31/31,\N,Benign,\N,3_prime_UTR_variant,8.262,0.6577,1KG_EAS_AF,OPA1
612651,3:193413517:T>C,NM_130837.2:c.*1128T>C,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,2.777,\N,\N,OPA1
612652,3:193413563:C>T,NM_130837.2:c.*1174C>T,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,7.216,\N,\N,OPA1
612653,3:193413593:G>A,NM_130837.2:c.*1204G>A,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,4.929,\N,\N,OPA1
612654,3:193413594:CT>C,NM_130837.2:c.*1210del,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,\N,\N,\N,OPA1
612655,3:193413597:T>C,NM_130837.2:c.*1208T>C,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,5.413,0.0008,1KG_AFR_AF,OPA1
612656,3:193413642:C>T,NM_130837.2:c.*1253C>T,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,4.784,\N,\N,OPA1
612657,3:193413644:A>G,NM_130837.2:c.*1255A>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,2.637,\N,\N,OPA1
612658,3:193413659:T>C,NM_130837.2:c.*1270T>C,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,5.59,\N,\N,OPA1
612659,3:193413660:G>C,NM_130837.2:c.*1271G>C,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,2.907,0.0014,1KG_AMR_AF,OPA1
612660,3:193413670:G>A,NM_130837.2:c.*1281G>A,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,6.746,0.001,1KG_EUR_AF,OPA1
612661,3:193413672:T>G,NM_130837.2:c.*1283T>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,7.586,\N,\N,OPA1
612662,3:193413688:C>T,NM_130837.2:c.*1299C>T,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,5.737,0.0014,1KG_AMR_AF,OPA1
612663,3:193413698:G>T,NM_130837.2:c.*1309G>T,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,2.483,0.0031,1KG_SAS_AF,OPA1
612664,3:193413709:A>C,NM_130837.2:c.*1320A>C,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,1.934,0.0014,1KG_AMR_AF,OPA1
612665,3:193413709:A>G,NM_130837.2:c.*1320A>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,3.982,\N,\N,OPA1
612666,3:193413732:A>G,NM_130837.2:c.*1343A>G,\N,31/31,\N,Benign,\N,3_prime_UTR_variant,4.898,0.7466,1KG_AFR_AF,OPA1
612667,3:193413797:T>C,NM_130837.2:c.*1408T>C,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,4.947,\N,\N,OPA1
612668,3:193413814:G>A,NM_130837.2:c.*1425G>A,\N,31/31,\N,Benign,\N,3_prime_UTR_variant,2.818,0.0169,1KG_EAS_AF,OPA1
612669,3:193413834:T>G,NM_130837.2:c.*1445T>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,7.35,0.0008,1KG_AFR_AF,OPA1
612670,3:193413844:G>A,NM_130837.2:c.*1455G>A,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,8.51,0.0023,1KG_AFR_AF,OPA1
612671,3:193413923:C>G,NM_130837.2:c.*1534C>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,3.868,\N,\N,OPA1
612672,3:193413947:T>G,NM_130837.2:c.*1558T>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,3.241,\N,\N,OPA1
612673,3:193413981:A>G,NM_130837.2:c.*1592A>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,1.916,\N,\N,OPA1
612674,3:193413987:A>G,NM_130837.2:c.*1598A>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,4.154,\N,\N,OPA1
612675,3:193413999:C>A,NM_130837.2:c.*1610C>A,\N,31/31,\N,Benign,\N,3_prime_UTR_variant,2.465,0.0083,1KG_AFR_AF,OPA1
612676,3:193413999:C>T,NM_130837.2:c.*1610C>T,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,2.567,0.0015,1KG_AFR_AF,OPA1
612677,3:193414058:G>A,NM_130837.2:c.*1669G>A,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,2.432,0.0015,1KG_AFR_AF,OPA1
612678,3:193414084:G>A,NM_130837.2:c.*1695G>A,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,7.089,0.0029,1KG_AMR_AF,OPA1
612679,3:193414095:A>AG,NM_130837.2:c.*1708dup,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,\N,\N,\N,OPA1
612680,3:193414101:A>G,NM_130837.2:c.*1712A>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,9.665,\N,\N,OPA1
612681,3:193414117:C>G,NM_130837.2:c.*1728C>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,3.052,\N,\N,OPA1
612682,3:193414200:C>T,NM_130837.2:c.*1811C>T,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,6.456,0.001,1KG_SAS_AF,OPA1
612683,3:193414203:A>G,NM_130837.2:c.*1814A>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,4.009,\N,\N,OPA1
612684,3:193414204:T>C,NM_130837.2:c.*1815T>C,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,4.032,\N,\N,OPA1
612685,3:193414214:T>G,NM_130837.2:c.*1825T>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,6.902,0.001,1KG_EAS_AF,OPA1
612686,3:193414234:A>T,NM_130837.2:c.*1845A>T,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,1.368,0.001,1KG_EAS_AF,OPA1
612687,3:193414240:C>T,NM_130837.2:c.*1851C>T,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,4.223,\N,\N,OPA1
612688,3:193414259:G>A,NM_130837.2:c.*1870G>A,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,3.175,\N,\N,OPA1
612689,3:193414273:C>T,NM_130837.2:c.*1884C>T,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,3.261,\N,\N,OPA1
612690,3:193414410:CAA>C,NM_130837.2:c.*2022_*2023del,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,\N,\N,\N,OPA1
612691,3:193414437:G>A,NM_130837.2:c.*2048G>A,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,4.628,\N,\N,OPA1
612692,3:193414457:G>C,NM_130837.2:c.*2068G>C,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,0.174,0.001,1KG_EUR_AF,OPA1
612693,3:193414474:A>C,NM_130837.2:c.*2085A>C,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,0.476,0.0014,1KG_AMR_AF,OPA1
612694,3:193414477:G>T,NM_130837.2:c.*2088G>T,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,4.241,0.0043,1KG_AMR_AF,OPA1
612695,3:193414481:C>T,NM_130837.2:c.*2092C>T,\N,31/31,\N,Benign,\N,3_prime_UTR_variant,1.751,0.5454,1KG_AFR_AF,OPA1
612696,3:193414504:G>A,NM_130837.2:c.*2115G>A,\N,31/31,\N,Benign,\N,3_prime_UTR_variant,1.863,0.0089,1KG_EAS_AF,OPA1
612697,3:193414506:A>G,NM_130837.2:c.*2117A>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,7.456,\N,\N,OPA1
612698,3:193414624:A>G,NM_130837.2:c.*2235A>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,5.759,0.0023,1KG_AFR_AF,OPA1
612699,3:193414630:A>G,NM_130837.2:c.*2241A>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,3.988,\N,\N,OPA1
612700,3:193414654:C>T,NM_130837.2:c.*2265C>T,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,6.15,\N,\N,OPA1
612701,3:193414675:T>C,NM_130837.2:c.*2286T>C,\N,31/31,\N,Benign,\N,3_prime_UTR_variant,5.174,0.0536,1KG_EAS_AF,OPA1
612702,3:193414685:A>C,NM_130837.2:c.*2296A>C,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,3.512,0.0008,1KG_AFR_AF,OPA1
612703,3:193414694:G>A,NM_130837.2:c.*2305G>A,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,4.449,0.002,1KG_SAS_AF,OPA1
612704,3:193414733:A>G,NM_130837.2:c.*2344A>G,\N,31/31,\N,Benign,\N,3_prime_UTR_variant,3.87,0.3876,1KG_AMR_AF,OPA1
612705,3:193414734:C>T,NM_130837.2:c.*2345C>T,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,5.477,0.0008,1KG_AFR_AF,OPA1
612706,3:193414780:T>C,NM_130837.2:c.*2391T>C,\N,31/31,\N,Benign,\N,3_prime_UTR_variant,3.918,0.5424,1KG_AFR_AF,OPA1
612707,3:193414793:G>A,NM_130837.2:c.*2404G>A,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,1.771,0.001,1KG_EAS_AF,OPA1
612708,3:193414797:A>G,NM_130837.2:c.*2408A>G,\N,31/31,\N,Benign,\N,3_prime_UTR_variant,4.466,0.0325,1KG_AFR_AF,OPA1
612709,3:193414805:C>T,NM_130837.2:c.*2416C>T,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,4.545,\N,\N,OPA1
612710,3:193414859:A>T,NM_130837.2:c.*2470A>T,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,3.176,\N,\N,OPA1
612711,3:193414871:G>A,NM_130837.2:c.*2482G>A,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,3.109,\N,\N,OPA1
612712,3:193414888:C>T,NM_130837.2:c.*2499C>T,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,4.943,0.001,1KG_EUR_AF,OPA1
612713,3:193414889:A>G,NM_130837.2:c.*2500A>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,4.812,0.001,1KG_EUR_AF,OPA1
612714,3:193414892:A>C,NM_130837.2:c.*2503A>C,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,1.709,\N,\N,OPA1
612715,3:193414901:T>C,NM_130837.2:c.*2512T>C,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,4.999,0.001,1KG_EUR_AF,OPA1
612716,3:193414951:G>A,NM_130837.2:c.*2562G>A,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,9.84,\N,\N,OPA1
612717,3:193414962:T>A,NM_130837.2:c.*2573T>A,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,6.986,\N,\N,OPA1
612718,3:193414975:T>A,NM_130837.2:c.*2586T>A,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,9.72,0.001,1KG_EUR_AF,OPA1
612719,3:193414985:T>C,NM_130837.2:c.*2596T>C,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,5.571,0.0008,1KG_AFR_AF,OPA1
612720,3:193415062:T>G,NM_130837.2:c.*2673T>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,8.182,0.001,1KG_EAS_AF,OPA1
612721,3:193415066:C>T,NM_130837.2:c.*2677C>T,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,7.432,\N,\N,OPA1
612722,3:193415069:G>A,NM_130837.2:c.*2680G>A,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,5.753,\N,\N,OPA1
612723,3:193415075:GT>G,NM_130837.2:c.*2688del,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,3.072,\N,\N,OPA1
612724,3:193415097:A>G,NM_130837.2:c.*2708A>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,13.36,0.0008,1KG_AFR_AF,OPA1
612725,3:193415109:A>G,NM_130837.2:c.*2720A>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,13.42,0.001,1KG_EUR_AF,OPA1
612726,3:193415139:A>G,NM_130837.2:c.*2750A>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,7.666,0.0041,1KG_SAS_AF,OPA1
612727,3:193415161:A>G,NM_130837.2:c.*2772A>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,13.03,\N,\N,OPA1
612728,3:193415190:A>G,NM_130837.2:c.*2801A>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,15.36,0.001,1KG_EAS_AF,OPA1
612729,3:193415217:C>A,NM_130837.2:c.*2828C>A,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,6.496,0.001,1KG_EAS_AF,OPA1
612730,3:193415222:A>G,NM_130837.2:c.*2833A>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,8.213,0.0008,1KG_AFR_AF,OPA1
612731,3:193415251:T>C,NM_130837.2:c.*2862T>C,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,15.98,\N,\N,OPA1
612732,3:193415262:A>T,NM_130837.2:c.*2873A>T,\N,31/31,\N,Benign,\N,3_prime_UTR_variant,16.22,0.177,1KG_AFR_AF,OPA1
612733,3:193415264:C>CTTG,NM_130837.2:c.*2876_*2878dup,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,16.37,\N,\N,OPA1
612734,3:193415293:T>C,NM_130837.2:c.*2904T>C,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,13.89,0.0008,1KG_AFR_AF,OPA1
612735,3:193415300:A>G,NM_130837.2:c.*2911A>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,14.77,0.001,1KG_EUR_AF,OPA1
612736,3:193415315:C>T,NM_130837.2:c.*2926C>T,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,13.59,\N,\N,OPA1
612737,3:193415327:A>G,NM_130837.2:c.*2938A>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,12.85,0.0029,1KG_AMR_AF,OPA1
612738,3:193415382:C>A,NM_130837.2:c.*2993C>A,\N,31/31,\N,Benign,\N,3_prime_UTR_variant,8.624,0.0184,1KG_SAS_AF,OPA1
612739,3:193415399:T>G,NM_130837.2:c.*3010T>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,12.36,\N,\N,OPA1
612740,3:193415416:A>G,NM_130837.2:c.*3027A>G,\N,31/31,\N,Benign,\N,3_prime_UTR_variant,10.91,0.0875,1KG_EUR_AF,OPA1
612741,3:193415527:T>TC,NM_130837.2:c.*3139dup,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,\N,\N,\N,OPA1
612742,3:193415529:A>C,NM_130837.2:c.*3140A>C,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,3.601,\N,\N,OPA1
612743,3:193415533:C>G,NM_130837.2:c.*3144C>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,2.079,\N,\N,OPA1
612744,3:193415533:C>T,NM_130837.2:c.*3144C>T,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,3.53,\N,\N,OPA1
612745,3:193415569:G>T,NM_130837.2:c.*3180G>T,\N,31/31,\N,Benign,\N,3_prime_UTR_variant,3.564,0.0051,1KG_SAS_AF,OPA1
612746,3:193415578:A>G,NM_130837.2:c.*3189A>G,\N,31/31,\N,Unknown significance,\N,3_prime_UTR_variant,4.285,0.0014,1KG_AMR_AF,OPA