id,variation,vep_hgvs_c,vep_hgvs_p,vep_exon,vep_intron,final_pathogenicity,final_disease,vep_consequence,vep_cadd_phred,overall_max_maf,overall_max_maf_source,gene
500753,21:45917775:C>A,NM_144991.2:c.*1891G>T,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,4.96,0.001,1KG_SAS_AF,TSPEAR
500754,21:45917784:T>TG,NM_144991.2:c.*1881dup,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,\N,\N,\N,TSPEAR
500755,21:45917799:T>C,NM_144991.2:c.*1867A>G,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,0.924,\N,\N,TSPEAR
500756,21:45917830:G>A,NM_144991.2:c.*1836C>T,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,4.777,0.0008,1KG_AFR_AF,TSPEAR
500757,21:45917894:G>A,NM_144991.2:c.*1772C>T,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,2.295,\N,\N,TSPEAR
500758,21:45917919:A>G,NM_144991.2:c.*1747T>C,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,1.23,\N,\N,TSPEAR
500759,21:45917931:T>G,NM_144991.2:c.*1735A>C,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,0.405,\N,\N,TSPEAR
500760,21:45918027:CAG>C,NM_144991.2:c.*1637_*1638del,\N,12/12,\N,Benign,\N,3_prime_UTR_variant,7.577,0.0159,1KG_AFR_AF,TSPEAR
500761,21:45918040:A>G,NM_144991.2:c.*1626T>C,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,0.305,0.001,1KG_SAS_AF,TSPEAR
500762,21:45918125:T>G,NM_144991.2:c.*1541A>C,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,7.321,0.0008,1KG_AFR_AF,TSPEAR
500763,21:45918134:T>C,NM_144991.2:c.*1532A>G,\N,12/12,\N,Benign,\N,3_prime_UTR_variant,1.632,0.1626,1KG_AFR_AF,TSPEAR
500764,21:45918142:T>G,NM_144991.2:c.*1524A>C,\N,12/12,\N,Benign,\N,3_prime_UTR_variant,2.257,0.0076,1KG_AFR_AF,TSPEAR
500765,21:45918146:T>A,NM_144991.2:c.*1520A>T,\N,12/12,\N,Benign,\N,3_prime_UTR_variant,1.925,0.0923,1KG_EAS_AF,TSPEAR
500766,21:45918166:T>A,NM_144991.2:c.*1500A>T,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,8.004,0.0014,1KG_AMR_AF,TSPEAR
500767,21:45918191:A>G,NM_144991.2:c.*1475T>C,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,0.108,\N,\N,TSPEAR
500768,21:45918211:T>C,NM_144991.2:c.*1455A>G,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,0.018,\N,\N,TSPEAR
500769,21:45918240:G>T,NM_144991.2:c.*1426C>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,0.75,0.003,1KG_EAS_AF,TSPEAR
500770,21:45918257:T>C,NM_144991.2:c.*1409A>G,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,1.205,0.001,1KG_EAS_AF,TSPEAR
500771,21:45918292:C>T,NM_144991.2:c.*1374G>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,3.651,\N,\N,TSPEAR
500772,21:45918305:G>A,NM_144991.2:c.*1361C>T,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,2.517,0.0008,1KG_AFR_AF,TSPEAR
500773,21:45918314:C>T,NM_144991.2:c.*1352G>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,0.439,0.0008,1KG_AFR_AF,TSPEAR
500774,21:45918315:G>A,NM_144991.2:c.*1351C>T,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,3.938,\N,\N,TSPEAR
500775,21:45918335:G>A,NM_144991.2:c.*1331C>T,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,4.308,0.0014,1KG_AMR_AF,TSPEAR
500776,21:45918372:C>T,NM_144991.2:c.*1294G>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,3.423,0.001,1KG_EUR_AF,TSPEAR
500777,21:45918380:C>T,NM_144991.2:c.*1286G>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,2.202,0.001,1KG_EUR_AF,TSPEAR
500778,21:45918388:C>A,NM_144991.2:c.*1278G>T,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,6.172,\N,\N,TSPEAR
500779,21:45918405:C>T,NM_144991.2:c.*1261G>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,6.005,\N,\N,TSPEAR
500780,21:45918406:G>A,NM_144991.2:c.*1260C>T,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,3.919,0.002,1KG_SAS_AF,TSPEAR
500781,21:45918414:T>C,NM_144991.2:c.*1252A>G,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,0.398,0.003,1KG_EUR_AF,TSPEAR
500782,21:45918424:G>A,NM_144991.2:c.*1242C>T,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,0.64,0.0008,1KG_AFR_AF,TSPEAR
500783,21:45918465:C>T,NM_144991.2:c.*1201G>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,5.409,\N,\N,TSPEAR
500784,21:45918511:C>T,NM_144991.2:c.*1155G>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,2.483,0.0038,1KG_AFR_AF,TSPEAR
500785,21:45918512:G>A,NM_144991.2:c.*1154C>T,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,1.299,0.001,1KG_EUR_AF,TSPEAR
500786,21:45918552:C>T,NM_144991.2:c.*1114G>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,8.753,\N,\N,TSPEAR
500787,21:45918553:G>A,NM_144991.2:c.*1113C>T,\N,12/12,\N,Benign,\N,3_prime_UTR_variant,7.337,0.0961,1KG_AFR_AF,TSPEAR
500788,21:45918560:G>A,NM_144991.2:c.*1106C>T,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,0.938,\N,\N,TSPEAR
500789,21:45918565:T>C,NM_144991.2:c.*1101A>G,\N,12/12,\N,Benign,\N,3_prime_UTR_variant,1.473,0.0061,1KG_AFR_AF,TSPEAR
500790,21:45918585:G>A,NM_144991.2:c.*1081C>T,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,2.98,\N,\N,TSPEAR
500791,21:45918593:TC>T,NM_144991.2:c.*1072del,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,\N,0.0029,1KG_AMR_AF,TSPEAR
500792,21:45918594:C>G,NM_144991.2:c.*1072G>C,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,2.813,0.0014,1KG_AMR_AF,TSPEAR
500793,21:45918599:T>G,NM_144991.2:c.*1067A>C,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,2.253,0.001,1KG_EAS_AF,TSPEAR
500794,21:45918609:G>A,NM_144991.2:c.*1057C>T,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,4.549,\N,\N,TSPEAR
500795,21:45918622:C>A,NM_144991.2:c.*1044G>T,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,0.293,\N,\N,TSPEAR
500796,21:45918622:C>T,NM_144991.2:c.*1044G>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,0.194,\N,\N,TSPEAR
500797,21:45918623:G>A,NM_144991.2:c.*1043C>T,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,3.163,0.002,1KG_EAS_AF,TSPEAR
500798,21:45918627:C>T,NM_144991.2:c.*1039G>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,4.316,0.003,1KG_EUR_AF,TSPEAR
500799,21:45918636:C>T,NM_144991.2:c.*1030G>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,1.767,\N,\N,TSPEAR
500800,21:45918664:C>T,NM_144991.2:c.*1002G>A,\N,12/12,\N,Benign,\N,3_prime_UTR_variant,2.167,0.0076,1KG_AFR_AF,TSPEAR
500801,21:45918667:C>T,NM_144991.2:c.*999G>A,\N,12/12,\N,Benign,\N,3_prime_UTR_variant,1.453,0.0053,1KG_AFR_AF,TSPEAR
500802,21:45918667:CG>C,NM_144991.2:c.*998del,\N,12/12,\N,Benign,\N,3_prime_UTR_variant,3.347,0.0787,1KG_AFR_AF,TSPEAR
500803,21:45918669:G>C,NM_144991.2:c.*997C>G,\N,12/12,\N,Benign,\N,3_prime_UTR_variant,1.07,0.0787,1KG_AFR_AF,TSPEAR
500804,21:45918757:C>T,NM_144991.2:c.*909G>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,3.625,0.0029,1KG_AMR_AF,TSPEAR
500805,21:45918765:AC>A,NM_144991.2:c.*900del,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,\N,\N,\N,TSPEAR
500806,21:45918788:G>A,NM_144991.2:c.*878C>T,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,4.105,\N,\N,TSPEAR
500807,21:45918792:C>T,NM_144991.2:c.*874G>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,3.616,0.001,1KG_EAS_AF,TSPEAR
500808,21:45918811:C>T,NM_144991.2:c.*855G>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,4.524,\N,\N,TSPEAR
500809,21:45918856:G>A,NM_144991.2:c.*810C>T,\N,12/12,\N,Benign,\N,3_prime_UTR_variant,6.803,0.0204,1KG_AFR_AF,TSPEAR
500810,21:45918880:C>T,NM_144991.2:c.*786G>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,5.178,\N,\N,TSPEAR
500811,21:45918915:T>TC,NM_144991.2:c.*750dup,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,\N,\N,\N,TSPEAR
500812,21:45918933:CAT>C,NM_144991.2:c.*731_*732del,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,\N,\N,\N,TSPEAR
500813,21:45918967:T>TC,NM_144991.2:c.*698dup,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,\N,\N,\N,TSPEAR
500814,21:45918970:C>T,NM_144991.2:c.*696G>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,1.954,\N,\N,TSPEAR
500815,21:45918971:G>A,NM_144991.2:c.*695C>T,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,4.541,0.003,1KG_EAS_AF,TSPEAR
500816,21:45919033:C>T,NM_144991.2:c.*633G>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,5.731,0.0008,1KG_AFR_AF,TSPEAR
500817,21:45919034:C>G,NM_144991.2:c.*632G>C,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,3.18,0.0008,1KG_AFR_AF,TSPEAR
500818,21:45919053:C>A,NM_144991.2:c.*613G>T,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,5.402,0.004,1KG_EUR_AF,TSPEAR
500819,21:45919058:C>T,NM_144991.2:c.*608G>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,2.088,0.001,1KG_SAS_AF,TSPEAR
500820,21:45919072:C>T,NM_144991.2:c.*594G>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,3.794,\N,\N,TSPEAR
500821,21:45919088:G>C,NM_144991.2:c.*578C>G,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,0.954,0.001,1KG_SAS_AF,TSPEAR
500822,21:45919093:G>T,NM_144991.2:c.*573C>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,2.256,0.0023,1KG_AFR_AF,TSPEAR
500823,21:45919102:T>C,NM_144991.2:c.*564A>G,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,2.175,\N,\N,TSPEAR
500824,21:45919110:T>C,NM_144991.2:c.*556A>G,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,1.353,\N,\N,TSPEAR
500825,21:45919132:T>C,NM_144991.2:c.*534A>G,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,1.455,\N,\N,TSPEAR
500826,21:45919137:G>A,NM_144991.2:c.*529C>T,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,2.686,0.001,1KG_SAS_AF,TSPEAR
500827,21:45919159:C>T,NM_144991.2:c.*507G>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,2.374,0.0008,1KG_AFR_AF,TSPEAR
500828,21:45919160:G>A,NM_144991.2:c.*506C>T,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,1.258,0.003,1KG_EAS_AF,TSPEAR
500829,21:45919165:C>T,NM_144991.2:c.*501G>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,0.263,0.0014,1KG_AMR_AF,TSPEAR
500830,21:45919168:G>A,NM_144991.2:c.*498C>T,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,4.513,\N,\N,TSPEAR
500831,21:45919178:C>T,NM_144991.2:c.*488G>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,3.408,\N,\N,TSPEAR
500832,21:45919182:T>G,NM_144991.2:c.*484A>C,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,2.172,0.0031,1KG_SAS_AF,TSPEAR
500833,21:45919199:G>A,NM_144991.2:c.*467C>T,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,3.316,\N,\N,TSPEAR
500834,21:45919203:A>G,NM_144991.2:c.*463T>C,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,8.178,0.001,1KG_SAS_AF,TSPEAR
500835,21:45919213:C>G,NM_144991.2:c.*453G>C,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,2.141,0.001,1KG_SAS_AF,TSPEAR
500836,21:45919219:A>G,NM_144991.2:c.*447T>C,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,3.7,\N,\N,TSPEAR
500837,21:45919243:C>T,NM_144991.2:c.*423G>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,2.518,0.002,1KG_EAS_AF,TSPEAR
500838,21:45919244:G>A,NM_144991.2:c.*422C>T,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,0.55,0.001,1KG_EUR_AF,TSPEAR
500839,21:45919267:CCTG>C,NM_144991.2:c.*396_*398del,\N,12/12,\N,Benign,\N,3_prime_UTR_variant,3.19,0.0356,1KG_AFR_AF,TSPEAR
500840,21:45919286:G>A,NM_144991.2:c.*380C>T,\N,12/12,\N,Benign,\N,3_prime_UTR_variant,0.345,0.1081,1KG_EAS_AF,TSPEAR
500841,21:45919290:A>G,NM_144991.2:c.*376T>C,\N,12/12,\N,Benign,\N,3_prime_UTR_variant,3.206,0.0092,1KG_SAS_AF,TSPEAR
500842,21:45919307:C>G,NM_144991.2:c.*359G>C,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,0.129,\N,\N,TSPEAR
500843,21:45919319:C>T,NM_144991.2:c.*347G>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,4.119,0.003,1KG_AFR_AF,TSPEAR
500844,21:45919338:G>T,NM_144991.2:c.*328C>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,2.776,\N,\N,TSPEAR
500845,21:45919345:T>G,NM_144991.2:c.*321A>C,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,4.866,\N,\N,TSPEAR
500846,21:45919370:C>T,NM_144991.2:c.*296G>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,3.989,0.0014,1KG_AMR_AF,TSPEAR
500847,21:45919393:C>T,NM_144991.2:c.*273G>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,3.193,0.0041,1KG_SAS_AF,TSPEAR
500848,21:45919401:A>G,NM_144991.2:c.*265T>C,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,1.998,\N,\N,TSPEAR
500849,21:45919413:G>A,NM_144991.2:c.*253C>T,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,3.462,0.0008,1KG_AFR_AF,TSPEAR
500850,21:45919423:A>AG,NM_144991.2:c.*242dup,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,1.243,\N,\N,TSPEAR
500851,21:45919540:C>T,NM_144991.2:c.*126G>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,5.776,0.001,1KG_EAS_AF,TSPEAR
500852,21:45919550:T>G,NM_144991.2:c.*116A>C,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,1.715,0.0023,1KG_AFR_AF,TSPEAR
500853,21:45919589:C>T,NM_144991.2:c.*77G>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,1.063,\N,\N,TSPEAR
500854,21:45919616:G>T,NM_144991.2:c.*50C>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,1.135,0.00473934,EXAC_EAS_AF,TSPEAR
500855,21:45919626:CCCACCTGGCCACCCCAGTTGCTGCCGGGCAGCCGCGGCCTCAGCGTGTCCTCAG>C,NM_144991.2:c.1996_*39del,\N,12/12,\N,Unknown significance,\N,stop_lost&3_prime_UTR_variant,15.2,0.00021106,EXAC_NFE_AF,TSPEAR
500856,21:45919651:C>T,NM_144991.2:c.*15G>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,2.717,\N,\N,TSPEAR
500857,21:45919652:G>A,NM_144991.2:c.*14C>T,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,2.933,0.00185185,EXAC_AFR_AF,TSPEAR
500858,21:45919655:C>T,NM_144991.2:c.*11G>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,0.234,0.00117647,EXAC_AFR_AF,TSPEAR
500859,21:45919656:A>C,NM_144991.2:c.*10T>G,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,0.112,\N,\N,TSPEAR
500860,21:45919659:C>T,NM_144991.2:c.*7G>A,\N,12/12,\N,Benign,\N,3_prime_UTR_variant,5.36,0.0172414,EXAC_FIN_AF,TSPEAR
500861,21:45919660:G>A,NM_144991.2:c.*6C>T,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,2.236,0.000278784,EXAC_NFE_AF,TSPEAR
500862,21:45919661:C>T,NM_144991.2:c.*5G>A,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,1.918,0.000540541,EXAC_AFR_AF,TSPEAR
500863,21:45919662:G>A,NM_144991.2:c.*4C>T,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,0.854,0.0010352,EXAC_AFR_AF,TSPEAR
500864,21:45919663:G>C,NM_144991.2:c.*3C>G,\N,12/12,\N,Unknown significance,\N,3_prime_UTR_variant,0.153,\N,\N,TSPEAR
500865,21:45919670:C>A,NM_144991.2:c.2006G>T,NP_659428.2:p.Arg669Leu,12/12,\N,Likely benign,\N,missense_variant,24.7,0.00105263,EXAC_EAS_AF,TSPEAR
500866,21:45919670:C>T,NM_144991.2:c.2006G>A,NP_659428.2:p.Arg669His,12/12,\N,Likely benign,\N,missense_variant,24.4,0.000463392,EXAC_AFR_AF,TSPEAR
500867,21:45919671:G>A,NM_144991.2:c.2005C>T,NP_659428.2:p.Arg669Cys,12/12,\N,Likely benign,\N,missense_variant,24.7,0.001,1KG_SAS_AF,TSPEAR
500868,21:45919672:T>A,NM_144991.2:c.2004A>T,NP_659428.2:p.Thr668=,12/12,\N,Unknown significance,\N,synonymous_variant,2.486,0.00129534,EXAC_AMR_AF,TSPEAR
500869,21:45919675:C>A,NM_144991.2:c.2001G>T,NP_659428.2:p.Arg667Ser,12/12,\N,Unknown significance,\N,missense_variant,23.8,\N,\N,TSPEAR
500870,21:45919681:C>T,NM_144991.2:c.1995G>A,NP_659428.2:p.Arg665=,12/12,\N,Unknown significance,\N,synonymous_variant,13.3,0.000408831,EXAC_AFR_AF,TSPEAR
500871,21:45919682:C>T,NM_144991.2:c.1994G>A,NP_659428.2:p.Arg665Gln,12/12,\N,Likely benign,\N,missense_variant,24.9,0.0008,1KG_AFR_AF,TSPEAR
500872,21:45919683:G>A,NM_144991.2:c.1993C>T,NP_659428.2:p.Arg665Trp,12/12,\N,Unknown significance,\N,missense_variant,32,0.000196078,EXAC_NFE_AF,TSPEAR
500873,21:45919694:G>C,NM_144991.2:c.1982C>G,NP_659428.2:p.Ser661Cys,12/12,\N,Unknown significance,\N,missense_variant,26.2,\N,\N,TSPEAR
500874,21:45919694:G>GA,NM_144991.2:c.1981dup,NP_659428.2:p.Ser661PhefsTer33,12/12,\N,Unknown significance,\N,frameshift_variant,35,\N,\N,TSPEAR
500875,21:45919697:A>C,NM_144991.2:c.1979T>G,NP_659428.2:p.Leu660Arg,12/12,\N,Unknown significance,\N,missense_variant,23.7,0.00246827,EXAC_AFR_AF,TSPEAR
500876,21:45919699:G>A,NM_144991.2:c.1977C>T,NP_659428.2:p.Pro659=,12/12,\N,Unknown significance,\N,synonymous_variant,10.69,\N,\N,TSPEAR
500877,21:45919702:C>A,NM_144991.2:c.1974G>T,NP_659428.2:p.Glu658Asp,12/12,\N,Unknown significance,\N,missense_variant,23,\N,\N,TSPEAR
500878,21:45919704:C>T,NM_144991.2:c.1972G>A,NP_659428.2:p.Glu658Lys,12/12,\N,Unknown significance,\N,missense_variant,24.5,0.00011919,EXAC_SAS_AF,TSPEAR
500879,21:45919710:C>T,NM_144991.2:c.1966G>A,NP_659428.2:p.Ala656Thr,12/12,\N,Unknown significance,\N,missense_variant,34,0.000726552,EXAC_NFE_AF,TSPEAR
500880,21:45919711:G>A,NM_144991.2:c.1965C>T,NP_659428.2:p.Ser655=,12/12,\N,Unknown significance,\N,synonymous_variant,11.46,0.000487329,EXAC_EAS_AF,TSPEAR
500881,21:45919715:G>C,NM_144991.2:c.1961C>G,NP_659428.2:p.Ser654Cys,12/12,\N,Unknown significance,\N,missense_variant,27.1,\N,\N,TSPEAR
500882,21:45919716:A>G,NM_144991.2:c.1960T>C,NP_659428.2:p.Ser654Pro,12/12,\N,Unknown significance,\N,missense_variant,29.9,0.0000557538,EXAC_NFE_AF,TSPEAR
500883,21:45919727:T>C,NM_144991.2:c.1949A>G,NP_659428.2:p.Tyr650Cys,12/12,\N,Unknown significance,\N,missense_variant,24.9,0.000319693,EXAC_AMR_AF,TSPEAR
500884,21:45919729:G>T,NM_144991.2:c.1947C>A,NP_659428.2:p.Ala649=,12/12,\N,Unknown significance,\N,synonymous_variant,7.561,0.0000439831,EXAC_NFE_AF,TSPEAR
500885,21:45919731:C>T,NM_144991.2:c.1945G>A,NP_659428.2:p.Ala649Thr,12/12,\N,Likely benign,\N,missense_variant,19.04,0.000106952,EXAC_SAS_AF,TSPEAR
500886,21:45919733:C>A,NM_144991.2:c.1943G>T,NP_659428.2:p.Gly648Val,12/12,\N,Unknown significance,\N,missense_variant,33,0.000228206,EVS_AA_AF,TSPEAR
500887,21:45919734:C>G,NM_144991.2:c.1942G>C,NP_659428.2:p.Gly648Arg,12/12,\N,Unknown significance,\N,missense_variant,32,\N,\N,TSPEAR
500888,21:45919738:C>T,NM_144991.2:c.1938G>A,NP_659428.2:p.Thr646=,12/12,\N,Unknown significance,\N,synonymous_variant,19.17,0.000239464,EXAC_AMR_AF,TSPEAR
500889,21:45919739:G>A,NM_144991.2:c.1937C>T,NP_659428.2:p.Thr646Met,12/12,\N,Unknown significance,\N,missense_variant,22.4,0.000219106,EXAC_AFR_AF,TSPEAR
500890,21:45919739:G>T,NM_144991.2:c.1937C>A,NP_659428.2:p.Thr646Lys,12/12,\N,Likely benign,\N,missense_variant,13.77,0.000685558,EXAC_AMR_AF,TSPEAR
500891,21:45919742:G>A,NM_144991.2:c.1934C>T,NP_659428.2:p.Thr645Ile,12/12,\N,Unknown significance,\N,missense_variant,22.3,0.002,1KG_EAS_AF,TSPEAR
500892,21:45919748:A>G,NM_144991.2:c.1928T>C,NP_659428.2:p.Phe643Ser,12/12,\N,Unknown significance,\N,missense_variant,32,0.0000972573,EXAC_SAS_AF,TSPEAR
500893,21:45919751:G>A,NM_144991.2:c.1925C>T,NP_659428.2:p.Ala642Val,12/12,\N,Unknown significance,\N,missense_variant,21.6,0.000145239,EXAC_NFE_AF,TSPEAR
500894,21:45919756:C>T,NM_144991.2:c.1920G>A,NP_659428.2:p.Trp640Ter,12/12,\N,Unknown significance,\N,stop_gained,47,0.0000272346,EXAC_NFE_AF,TSPEAR
500895,21:45919758:A>G,NM_144991.2:c.1918T>C,NP_659428.2:p.Trp640Arg,12/12,\N,Unknown significance,\N,missense_variant,28.3,0.000554119,EXAC_SAS_AF,TSPEAR
500896,21:45919761:C>T,NM_144991.2:c.1915G>A,NP_659428.2:p.Asp639Asn,12/12,\N,Benign,\N,missense_variant,34,0.00541005,EXAC_NFE_AF,TSPEAR
500897,21:45919762:C>T,NM_144991.2:c.1914G>A,NP_659428.2:p.Arg638=,12/12,\N,Unknown significance,\N,synonymous_variant,17.1,0.000270027,EXAC_SAS_AF,TSPEAR
500898,21:45919766:C>T,NM_144991.2:c.1910G>A,NP_659428.2:p.Cys637Tyr,12/12,\N,Unknown significance,\N,missense_variant,30,0.00012047,EXAC_NFE_AF,TSPEAR
500899,21:45919769:C>G,NM_144991.2:c.1907G>C,NP_659428.2:p.Gly636Ala,12/12,\N,Unknown significance,\N,missense_variant,24.4,\N,\N,TSPEAR
500900,21:45919770:C>T,NM_144991.2:c.1906G>A,NP_659428.2:p.Gly636Ser,12/12,\N,Unknown significance,\N,missense_variant,27.1,0.00017304,EXAC_SAS_AF,TSPEAR
500901,21:45919771:G>A,NM_144991.2:c.1905C>T,NP_659428.2:p.Val635=,12/12,\N,Unknown significance,\N,synonymous_variant,12.07,0.0000931836,EXAC_NFE_AF,TSPEAR
500902,21:45919773:C>T,NM_144991.2:c.1903G>A,NP_659428.2:p.Val635Ile,12/12,\N,Likely benign,\N,missense_variant,10.16,0.000163666,EXAC_AFR_AF,TSPEAR
500903,21:45919774:G>A,NM_144991.2:c.1902C>T,NP_659428.2:p.Thr634=,12/12,\N,Unknown significance,\N,synonymous_variant,13.82,\N,\N,TSPEAR
500904,21:45919777:G>A,NM_144991.2:c.1899C>T,NP_659428.2:p.Pro633=,12/12,\N,Unknown significance,\N,synonymous_variant,10.08,0.000157183,EXAC_EAS_AF,TSPEAR
500905,21:45919779:G>T,NM_144991.2:c.1897C>A,NP_659428.2:p.Pro633Thr,12/12,\N,Unknown significance,\N,missense_variant,27.1,0.0000222301,EXAC_NFE_AF,TSPEAR
500906,21:45919785:T>C,NM_144991.2:c.1891A>G,NP_659428.2:p.Ser631Gly,12/12,\N,Likely benign,\N,missense_variant,10.89,0.0000222074,EXAC_NFE_AF,TSPEAR
500907,21:45919790:A>ACCC,NM_144991.2:c.1885_1886insGGG,NP_659428.2:p.Ala628_Val629insGly,12/12,\N,Unknown significance,\N,inframe_insertion,\N,\N,\N,TSPEAR
500908,21:45919790:A>C,NM_144991.2:c.1886T>G,NP_659428.2:p.Val629Gly,12/12,\N,Unknown significance,\N,missense_variant,19.43,\N,\N,TSPEAR
500909,21:45919792:C>T,NM_144991.2:c.1884G>A,NP_659428.2:p.Ala628=,12/12,\N,Unknown significance,\N,synonymous_variant,17.1,0.000614062,EXAC_EAS_AF,TSPEAR
500910,21:45919793:G>A,NM_144991.2:c.1883C>T,NP_659428.2:p.Ala628Val,12/12,\N,Unknown significance,\N,missense_variant,23.3,0.0000215035,EXAC_NFE_AF,TSPEAR
500911,21:45919795:C>T,NM_144991.2:c.1881G>A,NP_659428.2:p.Val627=,12/12,\N,Unknown significance,\N,synonymous_variant,13.85,0.00015674,EXAC_AFR_AF,TSPEAR
500912,21:45919797:C>G,NM_144991.2:c.1879G>C,NP_659428.2:p.Val627Leu,12/12,\N,Unknown significance,\N,missense_variant,33,0.000359195,EXAC_FIN_AF,TSPEAR
500913,21:45919797:C>T,NM_144991.2:c.1879G>A,NP_659428.2:p.Val627Met,12/12,\N,Unknown significance,\N,missense_variant,34,0.0008,1KG_AFR_AF,TSPEAR
500914,21:45919798:G>A,NM_144991.2:c.1878C>T,NP_659428.2:p.Phe626=,12/12,\N,Unknown significance,\N,synonymous_variant,13.87,0.00214746,EXAC_FIN_AF,TSPEAR
500915,21:45919799:A>G,NM_144991.2:c.1877T>C,NP_659428.2:p.Phe626Ser,12/12,\N,Unknown significance,\N,missense_variant,32,0.000229991,EVS_AA_AF,TSPEAR
500916,21:45919801:G>A,NM_144991.2:c.1875C>T,NP_659428.2:p.Gly625=,12/12,\N,Unknown significance,\N,synonymous_variant,11.98,0.002,1KG_SAS_AF,TSPEAR
500917,21:45919803:C>T,NM_144991.2:c.1873G>A,NP_659428.2:p.Gly625Ser,12/12,\N,Unknown significance,\N,missense_variant,34,0.0018315,EXAC_OTH_AF,TSPEAR
500918,21:45919806:C>A,NM_144991.2:c.1870G>T,NP_659428.2:p.Glu624Ter,12/12,\N,Unknown significance,\N,stop_gained,52,0.000161551,EXAC_AFR_AF,TSPEAR
500919,21:45919806:C>T,NM_144991.2:c.1870G>A,NP_659428.2:p.Glu624Lys,12/12,\N,Unknown significance,\N,missense_variant,35,0.001,1KG_SAS_AF,TSPEAR
500920,21:45919807:G>A,NM_144991.2:c.1869C>T,NP_659428.2:p.Tyr623=,12/12,\N,Unknown significance,\N,synonymous_variant,9.655,0.00012279,EXAC_AMR_AF,TSPEAR
500921,21:45919809:A>G,NM_144991.2:c.1867T>C,NP_659428.2:p.Tyr623His,12/12,\N,Unknown significance,\N,missense_variant,28,\N,\N,TSPEAR
500922,21:45919816:C>T,NM_144991.2:c.1860G>A,NP_659428.2:p.Trp620Ter,12/12,\N,Unknown significance,\N,stop_gained,46,0.000167504,EXAC_AFR_AF,TSPEAR
500923,21:45919823:C>T,NM_144991.2:c.1857-4G>A,\N,\N,11/11,Unknown significance,\N,splice_region_variant&intron_variant,10.04,0.00011685,EVS_EA_AF,TSPEAR
500924,21:45919824:G>A,NM_144991.2:c.1857-5C>T,\N,\N,11/11,Unknown significance,\N,splice_region_variant&intron_variant,8.269,0.0014,1KG_AMR_AF,TSPEAR
500925,21:45919828:CAG>C,NM_144991.2:c.1857-11_1857-10del,\N,\N,11/11,Unknown significance,\N,intron_variant,8.655,0.0000251572,EXAC_NFE_AF,TSPEAR
500926,21:45919835:C>T,NM_144991.2:c.1857-16G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,5.788,0.0008,1KG_AFR_AF,TSPEAR
500927,21:45919842:C>T,NM_144991.2:c.1857-23G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,5.978,0.0000279111,EXAC_NFE_AF,TSPEAR
500928,21:45919843:G>T,NM_144991.2:c.1857-24C>A,\N,\N,11/11,Unknown significance,\N,intron_variant,0.453,\N,\N,TSPEAR
500929,21:45919861:C>T,NM_144991.2:c.1857-42G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,1.29,0.000606061,EXAC_EAS_AF,TSPEAR
500930,21:45919862:G>A,NM_144991.2:c.1857-43C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,5.667,0.000282008,EXAC_AFR_AF,TSPEAR
500931,21:45919876:C>T,NM_144991.2:c.1857-57G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,0.841,\N,\N,TSPEAR
500932,21:45919941:C>G,NM_144991.2:c.1857-122G>C,\N,\N,11/11,Unknown significance,\N,intron_variant,1.229,0.001,1KG_EUR_AF,TSPEAR
500933,21:45919944:C>T,NM_144991.2:c.1857-125G>A,\N,\N,11/11,Benign,\N,intron_variant,1.952,0.0325,1KG_AFR_AF,TSPEAR
500934,21:45919945:C>G,NM_144991.2:c.1857-126G>C,\N,\N,11/11,Unknown significance,\N,intron_variant,1.896,\N,\N,TSPEAR
500935,21:45919967:A>G,NM_144991.2:c.1857-148T>C,\N,\N,11/11,Unknown significance,\N,intron_variant,2.836,\N,\N,TSPEAR
500936,21:45919971:A>G,NM_144991.2:c.1857-152T>C,\N,\N,11/11,Unknown significance,\N,intron_variant,1.776,\N,\N,TSPEAR
500937,21:45920037:C>G,NM_144991.2:c.1857-218G>C,\N,\N,11/11,Unknown significance,\N,intron_variant,1.489,0.0015,1KG_AFR_AF,TSPEAR
500938,21:45920038:C>G,NM_144991.2:c.1857-219G>C,\N,\N,11/11,Unknown significance,\N,intron_variant,2.023,\N,\N,TSPEAR
500939,21:45920047:C>T,NM_144991.2:c.1857-228G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,6.379,0.0008,1KG_AFR_AF,TSPEAR
500940,21:45920055:C>A,NM_144991.2:c.1857-236G>T,\N,\N,11/11,Benign,\N,intron_variant,7.334,0.0119,1KG_EUR_AF,TSPEAR
500941,21:45920065:C>G,NM_144991.2:c.1857-246G>C,\N,\N,11/11,Unknown significance,\N,intron_variant,2.787,\N,\N,TSPEAR
500942,21:45920091:C>T,NM_144991.2:c.1857-272G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,2.205,\N,\N,TSPEAR
500943,21:45920105:C>A,NM_144991.2:c.1857-286G>T,\N,\N,11/11,Unknown significance,\N,intron_variant,3.733,0.003,1KG_AFR_AF,TSPEAR
500944,21:45920106:G>A,NM_144991.2:c.1857-287C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,2.901,0.001,1KG_EUR_AF,TSPEAR
500945,21:45920116:G>A,NM_144991.2:c.1857-297C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,1.704,\N,\N,TSPEAR
500946,21:45920131:T>C,NM_144991.2:c.1857-312A>G,\N,\N,11/11,Unknown significance,\N,intron_variant,1.174,0.001,1KG_EAS_AF,TSPEAR
500947,21:45920132:C>T,NM_144991.2:c.1857-313G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,0.679,\N,\N,TSPEAR
500948,21:45920133:G>A,NM_144991.2:c.1857-314C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,0.078,\N,\N,TSPEAR
500949,21:45920141:C>T,NM_144991.2:c.1857-322G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,4.489,0.0014,1KG_AMR_AF,TSPEAR
500950,21:45920174:G>T,NM_144991.2:c.1857-355C>A,\N,\N,11/11,Unknown significance,\N,intron_variant,0.071,0.0023,1KG_AFR_AF,TSPEAR
500951,21:45920179:C>T,NM_144991.2:c.1857-360G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,2.098,\N,\N,TSPEAR
500952,21:45920186:G>A,NM_144991.2:c.1857-367C>T,\N,\N,11/11,Benign,\N,intron_variant,0.322,0.0197,1KG_AFR_AF,TSPEAR
500953,21:45920192:T>A,NM_144991.2:c.1857-373A>T,\N,\N,11/11,Unknown significance,\N,intron_variant,1.209,\N,\N,TSPEAR
500954,21:45920222:C>G,NM_144991.2:c.1857-403G>C,\N,\N,11/11,Unknown significance,\N,intron_variant,2.647,\N,\N,TSPEAR
500955,21:45920236:G>A,NM_144991.2:c.1857-417C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,2.712,0.0043,1KG_AMR_AF,TSPEAR
500956,21:45920240:C>T,NM_144991.2:c.1857-421G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,5.69,\N,\N,TSPEAR
500957,21:45920245:C>T,NM_144991.2:c.1857-426G>A,\N,\N,11/11,Benign,\N,intron_variant,1.706,0.0853,1KG_EAS_AF,TSPEAR
500958,21:45920277:A>G,NM_144991.2:c.1857-458T>C,\N,\N,11/11,Unknown significance,\N,intron_variant,4.536,0.0038,1KG_AFR_AF,TSPEAR
500959,21:45920291:C>T,NM_144991.2:c.1857-472G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,3.184,0.003,1KG_AFR_AF,TSPEAR
500960,21:45920292:G>A,NM_144991.2:c.1857-473C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,0.782,0.0015,1KG_AFR_AF,TSPEAR
500961,21:45920305:C>T,NM_144991.2:c.1857-486G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,1.985,0.0008,1KG_AFR_AF,TSPEAR
500962,21:45920320:A>G,NM_144991.2:c.1857-501T>C,\N,\N,11/11,Unknown significance,\N,intron_variant,5.351,\N,\N,TSPEAR
500963,21:45920324:G>A,NM_144991.2:c.1857-505C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,4.67,\N,\N,TSPEAR
500964,21:45920345:T>C,NM_144991.2:c.1857-526A>G,\N,\N,11/11,Unknown significance,\N,intron_variant,0.952,0.0008,1KG_AFR_AF,TSPEAR
500965,21:45920353:C>T,NM_144991.2:c.1857-534G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,1.051,0.002,1KG_EAS_AF,TSPEAR
500966,21:45920354:G>A,NM_144991.2:c.1857-535C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,0.469,\N,\N,TSPEAR
500967,21:45920358:C>T,NM_144991.2:c.1857-539G>A,\N,\N,11/11,Benign,\N,intron_variant,4.566,0.0234,1KG_AFR_AF,TSPEAR
500968,21:45920377:G>C,NM_144991.2:c.1857-558C>G,\N,\N,11/11,Unknown significance,\N,intron_variant,2.113,0.0008,1KG_AFR_AF,TSPEAR
500969,21:45920382:C>T,NM_144991.2:c.1857-563G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,1.022,0.001,1KG_EAS_AF,TSPEAR
500970,21:45920400:G>A,NM_144991.2:c.1857-581C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,1.943,\N,\N,TSPEAR
500971,21:45920417:TTAAATAA>T,NM_144991.2:c.1857-605_1857-599del,\N,\N,11/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
500972,21:45920426:A>G,NM_144991.2:c.1857-607T>C,\N,\N,11/11,Unknown significance,\N,intron_variant,0.047,\N,\N,TSPEAR
500973,21:45920450:G>C,NM_144991.2:c.1857-631C>G,\N,\N,11/11,Unknown significance,\N,intron_variant,0.034,0.001,1KG_SAS_AF,TSPEAR
500974,21:45920467:A>G,NM_144991.2:c.1857-648T>C,\N,\N,11/11,Benign,\N,intron_variant,1.251,0.1165,1KG_AFR_AF,TSPEAR
500975,21:45920490:G>C,NM_144991.2:c.1857-671C>G,\N,\N,11/11,Unknown significance,\N,intron_variant,0.227,0.001,1KG_EAS_AF,TSPEAR
500976,21:45920491:G>C,NM_144991.2:c.1857-672C>G,\N,\N,11/11,Unknown significance,\N,intron_variant,0.526,0.002,1KG_SAS_AF,TSPEAR
500977,21:45920520:T>C,NM_144991.2:c.1857-701A>G,\N,\N,11/11,Benign,\N,intron_variant,0.105,0.0136,1KG_AFR_AF,TSPEAR
500978,21:45920694:A>AT,NM_144991.2:c.1857-876dup,\N,\N,11/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
500979,21:45920729:G>A,NM_144991.2:c.1857-910C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,0.036,0.0014,1KG_AMR_AF,TSPEAR
500980,21:45920742:A>AGAG,NM_144991.2:c.1857-926_1857-924dup,\N,\N,11/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
500981,21:45920747:T>G,NM_144991.2:c.1857-928A>C,\N,\N,11/11,Unknown significance,\N,intron_variant,3.614,0.0008,1KG_AFR_AF,TSPEAR
500982,21:45920757:C>A,NM_144991.2:c.1857-938G>T,\N,\N,11/11,Benign,\N,intron_variant,1.69,0.0242,1KG_AFR_AF,TSPEAR
500983,21:45920796:C>A,NM_144991.2:c.1857-977G>T,\N,\N,11/11,Unknown significance,\N,intron_variant,0.026,0.0023,1KG_AFR_AF,TSPEAR
500984,21:45920802:T>G,NM_144991.2:c.1857-983A>C,\N,\N,11/11,Unknown significance,\N,intron_variant,3.085,0.0008,1KG_AFR_AF,TSPEAR
500985,21:45920823:T>G,NM_144991.2:c.1857-1004A>C,\N,\N,11/11,Unknown significance,\N,intron_variant,2.193,0.001,1KG_EAS_AF,TSPEAR
500986,21:45920861:C>T,NM_144991.2:c.1857-1042G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,1.507,0.0015,1KG_AFR_AF,TSPEAR
500987,21:45920867:C>T,NM_144991.2:c.1857-1048G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,3.304,0.0008,1KG_AFR_AF,TSPEAR
500988,21:45920876:TTTC>T,NM_144991.2:c.1857-1060_1857-1058del,\N,\N,11/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
500989,21:45920882:C>G,NM_144991.2:c.1857-1063G>C,\N,\N,11/11,Unknown significance,\N,intron_variant,6.674,0.001,1KG_EUR_AF,TSPEAR
500990,21:45920908:A>G,NM_144991.2:c.1857-1089T>C,\N,\N,11/11,Unknown significance,\N,intron_variant,1.47,\N,\N,TSPEAR
500991,21:45920914:C>T,NM_144991.2:c.1857-1095G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,0.886,\N,\N,TSPEAR
500992,21:45920924:T>A,NM_144991.2:c.1857-1105A>T,\N,\N,11/11,Unknown significance,\N,intron_variant,4.163,0.002,1KG_SAS_AF,TSPEAR
500993,21:45920986:C>T,NM_144991.2:c.1857-1167G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,1.223,\N,\N,TSPEAR
500994,21:45920987:G>A,NM_144991.2:c.1857-1168C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,1.004,\N,\N,TSPEAR
500995,21:45921018:C>A,NM_144991.2:c.1857-1199G>T,\N,\N,11/11,Unknown significance,\N,intron_variant,7.257,\N,\N,TSPEAR
500996,21:45921038:A>C,NM_144991.2:c.1857-1219T>G,\N,\N,11/11,Benign,\N,intron_variant,0.599,0.0112,1KG_SAS_AF,TSPEAR
500997,21:45921058:C>T,NM_144991.2:c.1857-1239G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,0.451,\N,\N,TSPEAR
500998,21:45921059:G>A,NM_144991.2:c.1857-1240C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,1.192,0.001,1KG_SAS_AF,TSPEAR
500999,21:45921102:G>A,NM_144991.2:c.1857-1283C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,0.306,\N,\N,TSPEAR
501000,21:45921138:G>T,NM_144991.2:c.1857-1319C>A,\N,\N,11/11,Benign,\N,intron_variant,1.724,0.0595,1KG_EAS_AF,TSPEAR
501001,21:45921152:G>T,NM_144991.2:c.1857-1333C>A,\N,\N,11/11,Unknown significance,\N,intron_variant,0.474,\N,\N,TSPEAR
501002,21:45921168:A>G,NM_144991.2:c.1857-1349T>C,\N,\N,11/11,Unknown significance,\N,intron_variant,2.144,\N,\N,TSPEAR
501003,21:45921169:T>C,NM_144991.2:c.1857-1350A>G,\N,\N,11/11,Benign,\N,intron_variant,0.312,0.0149,1KG_EUR_AF,TSPEAR
501004,21:45921214:C>G,NM_144991.2:c.1857-1395G>C,\N,\N,11/11,Benign,\N,intron_variant,0.681,0.0197,1KG_AFR_AF,TSPEAR
501005,21:45921231:C>T,NM_144991.2:c.1857-1412G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,3.348,0.001,1KG_EUR_AF,TSPEAR
501006,21:45921232:A>G,NM_144991.2:c.1857-1413T>C,\N,\N,11/11,Unknown significance,\N,intron_variant,3.631,0.001,1KG_EUR_AF,TSPEAR
501007,21:45921238:G>A,NM_144991.2:c.1857-1419C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,2.735,0.001,1KG_EAS_AF,TSPEAR
501008,21:45921244:C>T,NM_144991.2:c.1857-1425G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,0.154,0.001,1KG_SAS_AF,TSPEAR
501009,21:45921249:C>T,NM_144991.2:c.1857-1430G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,0.16,\N,\N,TSPEAR
501010,21:45921273:TC>T,NM_144991.2:c.1857-1455del,\N,\N,11/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
501011,21:45921279:C>T,NM_144991.2:c.1857-1460G>A,\N,\N,11/11,Benign,\N,intron_variant,4.442,0.0113,1KG_AFR_AF,TSPEAR
501012,21:45921295:A>G,NM_144991.2:c.1857-1476T>C,\N,\N,11/11,Unknown significance,\N,intron_variant,0.237,0.002,1KG_EAS_AF,TSPEAR
501013,21:45921297:T>G,NM_144991.2:c.1857-1478A>C,\N,\N,11/11,Unknown significance,\N,intron_variant,4.707,\N,\N,TSPEAR
501014,21:45921354:C>T,NM_144991.2:c.1857-1535G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,4.737,0.002,1KG_EAS_AF,TSPEAR
501015,21:45921367:C>A,NM_144991.2:c.1857-1548G>T,\N,\N,11/11,Unknown significance,\N,intron_variant,0.911,0.001,1KG_SAS_AF,TSPEAR
501016,21:45921367:C>T,NM_144991.2:c.1857-1548G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,0.526,\N,\N,TSPEAR
501017,21:45921387:A>G,NM_144991.2:c.1857-1568T>C,\N,\N,11/11,Benign,\N,intron_variant,0.685,0.0106,1KG_AFR_AF,TSPEAR
501018,21:45921397:G>A,NM_144991.2:c.1857-1578C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,3.826,\N,\N,TSPEAR
501019,21:45921411:C>CG,NM_144991.2:c.1857-1593dup,\N,\N,11/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
501020,21:45921421:A>G,NM_144991.2:c.1857-1602T>C,\N,\N,11/11,Unknown significance,\N,intron_variant,3.497,0.001,1KG_SAS_AF,TSPEAR
501021,21:45921422:G>A,NM_144991.2:c.1857-1603C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,2.641,0.0008,1KG_AFR_AF,TSPEAR
501022,21:45921428:C>T,NM_144991.2:c.1857-1609G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,2.415,\N,\N,TSPEAR
501023,21:45921429:G>A,NM_144991.2:c.1857-1610C>T,\N,\N,11/11,Benign,\N,intron_variant,0.335,0.0159,1KG_AFR_AF,TSPEAR
501024,21:45921458:C>T,NM_144991.2:c.1857-1639G>A,\N,\N,11/11,Benign,\N,intron_variant,0.273,0.3591,1KG_EAS_AF,TSPEAR
501025,21:45921460:A>G,NM_144991.2:c.1857-1641T>C,\N,\N,11/11,Unknown significance,\N,intron_variant,1.792,\N,\N,TSPEAR
501026,21:45921467:G>A,NM_144991.2:c.1857-1648C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,0.241,0.001,1KG_EAS_AF,TSPEAR
501027,21:45921475:A>G,NM_144991.2:c.1857-1656T>C,\N,\N,11/11,Unknown significance,\N,intron_variant,2.37,\N,\N,TSPEAR
501028,21:45921518:C>T,NM_144991.2:c.1857-1699G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,9.372,0.001,1KG_EUR_AF,TSPEAR
501029,21:45921536:G>A,NM_144991.2:c.1857-1717C>T,\N,\N,11/11,Benign,\N,intron_variant,0.525,0.006,1KG_EAS_AF,TSPEAR
501030,21:45921572:T>G,NM_144991.2:c.1857-1753A>C,\N,\N,11/11,Unknown significance,\N,intron_variant,8.55,\N,\N,TSPEAR
501031,21:45921579:T>C,NM_144991.2:c.1857-1760A>G,\N,\N,11/11,Unknown significance,\N,intron_variant,7.449,\N,\N,TSPEAR
501032,21:45921606:C>T,NM_144991.2:c.1857-1787G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,3.414,0.0015,1KG_AFR_AF,TSPEAR
501033,21:45921614:C>T,NM_144991.2:c.1857-1795G>A,\N,\N,11/11,Benign,\N,intron_variant,2.633,0.0204,1KG_AFR_AF,TSPEAR
501034,21:45921639:C>T,NM_144991.2:c.1857-1820G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,6.396,0.0008,1KG_AFR_AF,TSPEAR
501035,21:45921662:TAAG>T,NM_144991.2:c.1857-1846_1857-1844del,\N,\N,11/11,Benign,\N,intron_variant,7.845,0.0204,1KG_AFR_AF,TSPEAR
501036,21:45921745:A>C,NM_144991.2:c.1857-1926T>G,\N,\N,11/11,Unknown significance,\N,intron_variant,0.09,0.0008,1KG_AFR_AF,TSPEAR
501037,21:45921798:C>T,NM_144991.2:c.1857-1979G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,2.767,\N,\N,TSPEAR
501038,21:45921833:G>A,NM_144991.2:c.1857-2014C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,1.833,\N,\N,TSPEAR
501039,21:45921834:G>C,NM_144991.2:c.1857-2015C>G,\N,\N,11/11,Unknown significance,\N,intron_variant,1.295,\N,\N,TSPEAR
501040,21:45921860:C>T,NM_144991.2:c.1857-2041G>A,\N,\N,11/11,Benign,\N,intron_variant,2.239,0.0325,1KG_AFR_AF,TSPEAR
501041,21:45921864:C>T,NM_144991.2:c.1857-2045G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,0.262,0.001,1KG_SAS_AF,TSPEAR
501042,21:45921879:C>T,NM_144991.2:c.1857-2060G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,4.723,0.0029,1KG_AMR_AF,TSPEAR
501043,21:45921888:G>A,NM_144991.2:c.1857-2069C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,2.932,\N,\N,TSPEAR
501044,21:45921913:A>G,NM_144991.2:c.1857-2094T>C,\N,\N,11/11,Unknown significance,\N,intron_variant,0.292,0.0023,1KG_AFR_AF,TSPEAR
501045,21:45921914:T>C,NM_144991.2:c.1857-2095A>G,\N,\N,11/11,Unknown significance,\N,intron_variant,1.228,0.002,1KG_SAS_AF,TSPEAR
501046,21:45921945:C>A,NM_144991.2:c.1857-2126G>T,\N,\N,11/11,Unknown significance,\N,intron_variant,3.098,0.0008,1KG_AFR_AF,TSPEAR
501047,21:45921953:C>T,NM_144991.2:c.1857-2134G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,1.509,\N,\N,TSPEAR
501048,21:45921960:G>A,NM_144991.2:c.1857-2141C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,2.099,0.001,1KG_EAS_AF,TSPEAR
501049,21:45921964:C>T,NM_144991.2:c.1857-2145G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,1.588,0.0015,1KG_AFR_AF,TSPEAR
501050,21:45921965:G>A,NM_144991.2:c.1857-2146C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,0.068,0.002,1KG_EUR_AF,TSPEAR
501051,21:45921977:G>A,NM_144991.2:c.1857-2158C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,0.912,0.0014,1KG_AMR_AF,TSPEAR
501052,21:45921982:G>A,NM_144991.2:c.1857-2163C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,0.852,\N,\N,TSPEAR
501053,21:45921986:T>C,NM_144991.2:c.1857-2167A>G,\N,\N,11/11,Unknown significance,\N,intron_variant,2.088,\N,\N,TSPEAR
501054,21:45921995:A>G,NM_144991.2:c.1857-2176T>C,\N,\N,11/11,Unknown significance,\N,intron_variant,2.764,\N,\N,TSPEAR
501055,21:45922001:C>A,NM_144991.2:c.1857-2182G>T,\N,\N,11/11,Unknown significance,\N,intron_variant,5.328,\N,\N,TSPEAR
501056,21:45922012:C>T,NM_144991.2:c.1857-2193G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,4.14,0.001,1KG_SAS_AF,TSPEAR
501057,21:45922033:C>T,NM_144991.2:c.1857-2214G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,0.109,0.001,1KG_EAS_AF,TSPEAR
501058,21:45922036:C>T,NM_144991.2:c.1857-2217G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,1.618,\N,\N,TSPEAR
501059,21:45922049:G>A,NM_144991.2:c.1857-2230C>T,\N,\N,11/11,Benign,\N,intron_variant,3.753,0.0129,1KG_AFR_AF,TSPEAR
501060,21:45922054:A>G,NM_144991.2:c.1857-2235T>C,\N,\N,11/11,Unknown significance,\N,intron_variant,1.232,\N,\N,TSPEAR
501061,21:45922072:C>T,NM_144991.2:c.1857-2253G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,3.771,0.0029,1KG_AMR_AF,TSPEAR
501062,21:45922075:G>A,NM_144991.2:c.1857-2256C>T,\N,\N,11/11,Benign,\N,intron_variant,2.654,0.1498,1KG_AFR_AF,TSPEAR
501063,21:45922097:C>T,NM_144991.2:c.1857-2278G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,3.892,0.0014,1KG_AMR_AF,TSPEAR
501064,21:45922157:G>A,NM_144991.2:c.1857-2338C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,0.506,0.0038,1KG_AFR_AF,TSPEAR
501065,21:45922232:G>C,NM_144991.2:c.1857-2413C>G,\N,\N,11/11,Unknown significance,\N,intron_variant,1.157,0.0015,1KG_AFR_AF,TSPEAR
501066,21:45922233:G>A,NM_144991.2:c.1857-2414C>T,\N,\N,11/11,Benign,\N,intron_variant,2.857,0.0962,1KG_EAS_AF,TSPEAR
501067,21:45922246:T>C,NM_144991.2:c.1856+2417A>G,\N,\N,11/11,Unknown significance,\N,intron_variant,1.043,0.003,1KG_AFR_AF,TSPEAR
501068,21:45922258:A>G,NM_144991.2:c.1856+2405T>C,\N,\N,11/11,Benign,\N,intron_variant,2.113,0.0098,1KG_AFR_AF,TSPEAR
501069,21:45922262:C>T,NM_144991.2:c.1856+2401G>A,\N,\N,11/11,Benign,\N,intron_variant,2.367,0.1611,1KG_AFR_AF,TSPEAR
501070,21:45922265:T>G,NM_144991.2:c.1856+2398A>C,\N,\N,11/11,Unknown significance,\N,intron_variant,2.894,\N,\N,TSPEAR
501071,21:45922298:C>G,NM_144991.2:c.1856+2365G>C,\N,\N,11/11,Unknown significance,\N,intron_variant,2.033,0.0008,1KG_AFR_AF,TSPEAR
501072,21:45922323:C>T,NM_144991.2:c.1856+2340G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,3.909,0.0015,1KG_AFR_AF,TSPEAR
501073,21:45922324:G>A,NM_144991.2:c.1856+2339C>T,\N,\N,11/11,Benign,\N,intron_variant,0.15,0.0189,1KG_AFR_AF,TSPEAR
501074,21:45922383:G>A,NM_144991.2:c.1856+2280C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,1.158,0.001,1KG_EUR_AF,TSPEAR
501075,21:45922390:G>A,NM_144991.2:c.1856+2273C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,0.835,0.0045,1KG_AFR_AF,TSPEAR
501076,21:45922393:C>T,NM_144991.2:c.1856+2270G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,0.16,0.001,1KG_EAS_AF,TSPEAR
501077,21:45922403:A>G,NM_144991.2:c.1856+2260T>C,\N,\N,11/11,Unknown significance,\N,intron_variant,2.572,0.0008,1KG_AFR_AF,TSPEAR
501078,21:45922420:A>G,NM_144991.2:c.1856+2243T>C,\N,\N,11/11,Unknown significance,\N,intron_variant,2.196,\N,\N,TSPEAR
501079,21:45922421:T>C,NM_144991.2:c.1856+2242A>G,\N,\N,11/11,Benign,\N,intron_variant,0.426,0.0091,1KG_AFR_AF,TSPEAR
501080,21:45922429:C>T,NM_144991.2:c.1856+2234G>A,\N,\N,11/11,Benign,\N,intron_variant,3.163,0.0149,1KG_EUR_AF,TSPEAR
501081,21:45922476:A>T,NM_144991.2:c.1856+2187T>A,\N,\N,11/11,Unknown significance,\N,intron_variant,1.791,0.001,1KG_SAS_AF,TSPEAR
501082,21:45922491:C>T,NM_144991.2:c.1856+2172G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,1.73,\N,\N,TSPEAR
501083,21:45922497:CCTG>C,NM_144991.2:c.1856+2163_1856+2165del,\N,\N,11/11,Unknown significance,\N,intron_variant,\N,0.003,1KG_EAS_AF,TSPEAR
501084,21:45922502:C>T,NM_144991.2:c.1856+2161G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,4.354,0.0008,1KG_AFR_AF,TSPEAR
501085,21:45922529:C>T,NM_144991.2:c.1856+2134G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,3.983,\N,\N,TSPEAR
501086,21:45922531:C>T,NM_144991.2:c.1856+2132G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,4.192,0.001,1KG_EUR_AF,TSPEAR
501087,21:45922532:G>A,NM_144991.2:c.1856+2131C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,1.53,\N,\N,TSPEAR
501088,21:45922550:C>T,NM_144991.2:c.1856+2113G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,1.96,0.0014,1KG_AMR_AF,TSPEAR
501089,21:45922579:C>T,NM_144991.2:c.1856+2084G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,3.853,0.001,1KG_EAS_AF,TSPEAR
501090,21:45922587:G>GC,NM_144991.2:c.1856+2075dup,\N,\N,11/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
501091,21:45922589:C>T,NM_144991.2:c.1856+2074G>A,\N,\N,11/11,Benign,\N,intron_variant,5.467,0.0068,1KG_AFR_AF,TSPEAR
501092,21:45922592:C>T,NM_144991.2:c.1856+2071G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,2.408,\N,\N,TSPEAR
501093,21:45922613:C>T,NM_144991.2:c.1856+2050G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,3.611,\N,\N,TSPEAR
501094,21:45922615:G>A,NM_144991.2:c.1856+2048C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,4.461,\N,\N,TSPEAR
501095,21:45922615:G>C,NM_144991.2:c.1856+2048C>G,\N,\N,11/11,Unknown significance,\N,intron_variant,1.578,0.0008,1KG_AFR_AF,TSPEAR
501096,21:45922619:A>G,NM_144991.2:c.1856+2044T>C,\N,\N,11/11,Unknown significance,\N,intron_variant,0.443,0.001,1KG_SAS_AF,TSPEAR
501097,21:45922623:C>T,NM_144991.2:c.1856+2040G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,1.903,0.0008,1KG_AFR_AF,TSPEAR
501098,21:45922624:G>A,NM_144991.2:c.1856+2039C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,1.629,0.0008,1KG_AFR_AF,TSPEAR
501099,21:45922634:C>A,NM_144991.2:c.1856+2029G>T,\N,\N,11/11,Benign,\N,intron_variant,2.943,0.0082,1KG_SAS_AF,TSPEAR
501100,21:45922643:G>A,NM_144991.2:c.1856+2020C>T,\N,\N,11/11,Benign,\N,intron_variant,2.939,0.0204,1KG_AFR_AF,TSPEAR
501101,21:45922648:C>T,NM_144991.2:c.1856+2015G>A,\N,\N,11/11,Benign,\N,intron_variant,4.925,0.0061,1KG_AFR_AF,TSPEAR
501102,21:45922652:G>A,NM_144991.2:c.1856+2011C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,2.014,\N,\N,TSPEAR
501103,21:45922652:G>C,NM_144991.2:c.1856+2011C>G,\N,\N,11/11,Unknown significance,\N,intron_variant,0.652,0.001,1KG_EAS_AF,TSPEAR
501104,21:45922658:C>T,NM_144991.2:c.1856+2005G>A,\N,\N,11/11,Benign,\N,intron_variant,3.175,0.0229,1KG_EUR_AF,TSPEAR
501105,21:45922659:G>A,NM_144991.2:c.1856+2004C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,0.629,0.001,1KG_SAS_AF,TSPEAR
501106,21:45922683:G>GC,NM_144991.2:c.1856+1979dup,\N,\N,11/11,Unknown significance,\N,intron_variant,2.046,0.003,1KG_AFR_AF,TSPEAR
501107,21:45922688:C>CG,NM_144991.2:c.1856+1974dup,\N,\N,11/11,Unknown significance,\N,intron_variant,3.452,\N,\N,TSPEAR
501108,21:45922695:A>G,NM_144991.2:c.1856+1968T>C,\N,\N,11/11,Unknown significance,\N,intron_variant,3.095,0.0043,1KG_AMR_AF,TSPEAR
501109,21:45922708:G>T,NM_144991.2:c.1856+1955C>A,\N,\N,11/11,Unknown significance,\N,intron_variant,1.803,\N,\N,TSPEAR
501110,21:45922709:G>GA,NM_144991.2:c.1856+1953dup,\N,\N,11/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
501111,21:45922712:G>A,NM_144991.2:c.1856+1951C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,4.206,\N,\N,TSPEAR
501112,21:45922718:G>A,NM_144991.2:c.1856+1945C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,5.382,\N,\N,TSPEAR
501113,21:45922724:G>C,NM_144991.2:c.1856+1939C>G,\N,\N,11/11,Benign,\N,intron_variant,1.652,0.0153,1KG_SAS_AF,TSPEAR
501114,21:45922727:G>A,NM_144991.2:c.1856+1936C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,6.446,0.001,1KG_EUR_AF,TSPEAR
501115,21:45922733:T>C,NM_144991.2:c.1856+1930A>G,\N,\N,11/11,Benign,\N,intron_variant,0.235,0.0061,1KG_SAS_AF,TSPEAR
501116,21:45922733:TTG>T,NM_144991.2:c.1856+1928_1856+1929del,\N,\N,11/11,Unknown significance,\N,intron_variant,5.302,\N,\N,TSPEAR
501117,21:45922735:G>A,NM_144991.2:c.1856+1928C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,4.381,\N,\N,TSPEAR
501118,21:45922735:G>C,NM_144991.2:c.1856+1928C>G,\N,\N,11/11,Unknown significance,\N,intron_variant,1.325,\N,\N,TSPEAR
501119,21:45922736:G>C,NM_144991.2:c.1856+1927C>G,\N,\N,11/11,Benign,\N,intron_variant,0.041,0.0113,1KG_AFR_AF,TSPEAR
501120,21:45922760:G>A,NM_144991.2:c.1856+1903C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,0.354,\N,\N,TSPEAR
501121,21:45922761:G>A,NM_144991.2:c.1856+1902C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,2.78,\N,\N,TSPEAR
501122,21:45922761:G>T,NM_144991.2:c.1856+1902C>A,\N,\N,11/11,Benign,\N,intron_variant,0.691,0.0113,1KG_AFR_AF,TSPEAR
501123,21:45922763:C>T,NM_144991.2:c.1856+1900G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,0.674,\N,\N,TSPEAR
501124,21:45922764:G>A,NM_144991.2:c.1856+1899C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,2.228,\N,\N,TSPEAR
501125,21:45922770:G>A,NM_144991.2:c.1856+1893C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,2.318,0.002,1KG_EUR_AF,TSPEAR
501126,21:45922771:G>A,NM_144991.2:c.1856+1892C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,3.903,0.0014,1KG_AMR_AF,TSPEAR
501127,21:45922779:T>C,NM_144991.2:c.1856+1884A>G,\N,\N,11/11,Unknown significance,\N,intron_variant,4.684,\N,\N,TSPEAR
501128,21:45922780:C>T,NM_144991.2:c.1856+1883G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,0.322,0.0031,1KG_SAS_AF,TSPEAR
501129,21:45922787:G>GT,NM_144991.2:c.1856+1875dup,\N,\N,11/11,Benign,\N,intron_variant,\N,0.0051,1KG_SAS_AF,TSPEAR
501130,21:45922787:G>T,NM_144991.2:c.1856+1876C>A,\N,\N,11/11,Unknown significance,\N,intron_variant,1.245,0.0008,1KG_AFR_AF,TSPEAR
501131,21:45922794:G>A,NM_144991.2:c.1856+1869C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,0.203,\N,\N,TSPEAR
501132,21:45922794:G>T,NM_144991.2:c.1856+1869C>A,\N,\N,11/11,Benign,\N,intron_variant,0.068,0.0204,1KG_AFR_AF,TSPEAR
501133,21:45922803:A>G,NM_144991.2:c.1856+1860T>C,\N,\N,11/11,Unknown significance,\N,intron_variant,4.697,\N,\N,TSPEAR
501134,21:45922807:T>C,NM_144991.2:c.1856+1856A>G,\N,\N,11/11,Benign,\N,intron_variant,0.411,0.4632,1KG_SAS_AF,TSPEAR
501135,21:45922808:G>A,NM_144991.2:c.1856+1855C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,4.605,0.001,1KG_EUR_AF,TSPEAR
501136,21:45922814:A>G,NM_144991.2:c.1856+1849T>C,\N,\N,11/11,Benign,\N,intron_variant,4.078,0.4632,1KG_SAS_AF,TSPEAR
501137,21:45922824:C>CGG,NM_144991.2:c.1856+1837_1856+1838dup,\N,\N,11/11,Benign,\N,intron_variant,5.343,0.4172,1KG_SAS_AF,TSPEAR
501138,21:45922824:C>T,NM_144991.2:c.1856+1839G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,3.621,0.0008,1KG_AFR_AF,TSPEAR
501139,21:45922825:G>A,NM_144991.2:c.1856+1838C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,3.863,\N,\N,TSPEAR
501140,21:45922832:C>T,NM_144991.2:c.1856+1831G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,3.01,0.0023,1KG_AFR_AF,TSPEAR
501141,21:45922848:A>G,NM_144991.2:c.1856+1815T>C,\N,\N,11/11,Unknown significance,\N,intron_variant,0.179,\N,\N,TSPEAR
501142,21:45922851:T>C,NM_144991.2:c.1856+1812A>G,\N,\N,11/11,Unknown significance,\N,intron_variant,2.033,\N,\N,TSPEAR
501143,21:45922858:G>A,NM_144991.2:c.1856+1805C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,4.049,0.0008,1KG_AFR_AF,TSPEAR
501144,21:45922867:A>T,NM_144991.2:c.1856+1796T>A,\N,\N,11/11,Benign,\N,intron_variant,5.148,0.005,1KG_EAS_AF,TSPEAR
501145,21:45922870:GT>G,NM_144991.2:c.1856+1792del,\N,\N,11/11,Benign,\N,intron_variant,\N,0.005,1KG_EAS_AF,TSPEAR
501146,21:45922879:C>T,NM_144991.2:c.1856+1784G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,4.498,\N,\N,TSPEAR
501147,21:45922884:T>C,NM_144991.2:c.1856+1779A>G,\N,\N,11/11,Unknown significance,\N,intron_variant,0.164,\N,\N,TSPEAR
501148,21:45922893:G>A,NM_144991.2:c.1856+1770C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,3.295,\N,\N,TSPEAR
501149,21:45922895:A>G,NM_144991.2:c.1856+1768T>C,\N,\N,11/11,Unknown significance,\N,intron_variant,0.979,\N,\N,TSPEAR
501150,21:45922898:C>T,NM_144991.2:c.1856+1765G>A,\N,\N,11/11,Benign,\N,intron_variant,6.051,0.1029,1KG_AFR_AF,TSPEAR
501151,21:45922902:C>T,NM_144991.2:c.1856+1761G>A,\N,\N,11/11,Benign,\N,intron_variant,2.551,0.0182,1KG_AFR_AF,TSPEAR
501152,21:45922907:T>G,NM_144991.2:c.1856+1756A>C,\N,\N,11/11,Unknown significance,\N,intron_variant,5.187,0.002,1KG_EAS_AF,TSPEAR
501153,21:45922911:C>T,NM_144991.2:c.1856+1752G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,4.86,\N,\N,TSPEAR
501154,21:45922915:C>T,NM_144991.2:c.1856+1748G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,0.106,\N,\N,TSPEAR
501155,21:45922941:A>G,NM_144991.2:c.1856+1722T>C,\N,\N,11/11,Unknown significance,\N,intron_variant,0.084,\N,\N,TSPEAR
501156,21:45922944:T>C,NM_144991.2:c.1856+1719A>G,\N,\N,11/11,Unknown significance,\N,intron_variant,1,\N,\N,TSPEAR
501157,21:45922950:C>T,NM_144991.2:c.1856+1713G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,1.336,0.0023,1KG_AFR_AF,TSPEAR
501158,21:45922957:C>T,NM_144991.2:c.1856+1706G>A,\N,\N,11/11,Benign,\N,intron_variant,4.224,0.0809,1KG_AFR_AF,TSPEAR
501159,21:45922962:A>G,NM_144991.2:c.1856+1701T>C,\N,\N,11/11,Benign,\N,intron_variant,2.573,0.1104,1KG_AFR_AF,TSPEAR
501160,21:45922975:A>G,NM_144991.2:c.1856+1688T>C,\N,\N,11/11,Benign,\N,intron_variant,1.882,0.1377,1KG_AFR_AF,TSPEAR
501161,21:45922976:C>T,NM_144991.2:c.1856+1687G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,0.361,\N,\N,TSPEAR
501162,21:45922991:G>A,NM_144991.2:c.1856+1672C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,3.914,0.001,1KG_SAS_AF,TSPEAR
501163,21:45923003:T>C,NM_144991.2:c.1856+1660A>G,\N,\N,11/11,Unknown significance,\N,intron_variant,2.965,\N,\N,TSPEAR
501164,21:45923009:G>C,NM_144991.2:c.1856+1654C>G,\N,\N,11/11,Benign,\N,intron_variant,0.018,0.0053,1KG_AFR_AF,TSPEAR
501165,21:45923034:G>T,NM_144991.2:c.1856+1629C>A,\N,\N,11/11,Unknown significance,\N,intron_variant,1.701,0.001,1KG_EAS_AF,TSPEAR
501166,21:45923043:G>A,NM_144991.2:c.1856+1620C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,3.644,0.001,1KG_SAS_AF,TSPEAR
501167,21:45923063:C>T,NM_144991.2:c.1856+1600G>A,\N,\N,11/11,Benign,\N,intron_variant,5.524,0.0204,1KG_AFR_AF,TSPEAR
501168,21:45923081:CAG>C,NM_144991.2:c.1856+1580_1856+1581del,\N,\N,11/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
501169,21:45923084:G>C,NM_144991.2:c.1856+1579C>G,\N,\N,11/11,Unknown significance,\N,intron_variant,1.238,0.002,1KG_EUR_AF,TSPEAR
501170,21:45923084:G>T,NM_144991.2:c.1856+1579C>A,\N,\N,11/11,Benign,\N,intron_variant,2.006,0.0109,1KG_EAS_AF,TSPEAR
501171,21:45923088:G>A,NM_144991.2:c.1856+1575C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,4.814,0.001,1KG_EUR_AF|1KG_SAS_AF,TSPEAR
501172,21:45923088:G>T,NM_144991.2:c.1856+1575C>A,\N,\N,11/11,Benign,\N,intron_variant,2.289,0.0257,1KG_AFR_AF,TSPEAR
501173,21:45923088:GA>G,NM_144991.2:c.1856+1574del,\N,\N,11/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
501174,21:45923128:C>T,NM_144991.2:c.1856+1535G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,4.7,0.0008,1KG_AFR_AF,TSPEAR
501175,21:45923131:G>T,NM_144991.2:c.1856+1532C>A,\N,\N,11/11,Unknown significance,\N,intron_variant,2.957,0.0008,1KG_AFR_AF,TSPEAR
501176,21:45923133:G>C,NM_144991.2:c.1856+1530C>G,\N,\N,11/11,Unknown significance,\N,intron_variant,1.597,0.001,1KG_SAS_AF,TSPEAR
501177,21:45923175:G>A,NM_144991.2:c.1856+1488C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,0.585,0.001,1KG_EAS_AF,TSPEAR
501178,21:45923179:G>T,NM_144991.2:c.1856+1484C>A,\N,\N,11/11,Benign,\N,intron_variant,2.09,0.0159,1KG_AFR_AF,TSPEAR
501179,21:45923180:G>A,NM_144991.2:c.1856+1483C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,4.266,0.001,1KG_EAS_AF,TSPEAR
501180,21:45923184:C>A,NM_144991.2:c.1856+1479G>T,\N,\N,11/11,Unknown significance,\N,intron_variant,8.119,\N,\N,TSPEAR
501181,21:45923191:C>T,NM_144991.2:c.1856+1472G>A,\N,\N,11/11,Benign,\N,intron_variant,5.571,0.0194,1KG_SAS_AF,TSPEAR
501182,21:45923203:C>T,NM_144991.2:c.1856+1460G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,2.4,\N,\N,TSPEAR
501183,21:45923209:T>C,NM_144991.2:c.1856+1454A>G,\N,\N,11/11,Unknown significance,\N,intron_variant,0.218,\N,\N,TSPEAR
501184,21:45923221:G>A,NM_144991.2:c.1856+1442C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,1.071,0.0043,1KG_AMR_AF,TSPEAR
501185,21:45923223:G>A,NM_144991.2:c.1856+1440C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,2.22,0.0043,1KG_AMR_AF,TSPEAR
501186,21:45923256:G>C,NM_144991.2:c.1856+1407C>G,\N,\N,11/11,Benign,\N,intron_variant,1.144,0.1925,1KG_EAS_AF,TSPEAR
501187,21:45923267:G>T,NM_144991.2:c.1856+1396C>A,\N,\N,11/11,Unknown significance,\N,intron_variant,0.072,0.0015,1KG_AFR_AF,TSPEAR
501188,21:45923312:C>CG,NM_144991.2:c.1856+1350dup,\N,\N,11/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
501189,21:45923347:C>T,NM_144991.2:c.1856+1316G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,6.414,\N,\N,TSPEAR
501190,21:45923348:G>A,NM_144991.2:c.1856+1315C>T,\N,\N,11/11,Benign,\N,intron_variant,4.297,0.0325,1KG_AFR_AF,TSPEAR
501191,21:45923368:A>C,NM_144991.2:c.1856+1295T>G,\N,\N,11/11,Unknown significance,\N,intron_variant,0.453,\N,\N,TSPEAR
501192,21:45923384:G>A,NM_144991.2:c.1856+1279C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,0.187,\N,\N,TSPEAR
501193,21:45923404:TGGG>T,NM_144991.2:c.1856+1256_1856+1258del,\N,\N,11/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
501194,21:45923405:G>A,NM_144991.2:c.1856+1258C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,5.594,0.001,1KG_EAS_AF,TSPEAR
501195,21:45923406:G>C,NM_144991.2:c.1856+1257C>G,\N,\N,11/11,Unknown significance,\N,intron_variant,2.17,0.001,1KG_EUR_AF,TSPEAR
501196,21:45923406:G>T,NM_144991.2:c.1856+1257C>A,\N,\N,11/11,Unknown significance,\N,intron_variant,3.234,\N,\N,TSPEAR
501197,21:45923415:C>T,NM_144991.2:c.1856+1248G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,6.947,0.0008,1KG_AFR_AF,TSPEAR
501198,21:45923431:A>G,NM_144991.2:c.1856+1232T>C,\N,\N,11/11,Unknown significance,\N,intron_variant,6.513,\N,\N,TSPEAR
501199,21:45923434:G>T,NM_144991.2:c.1856+1229C>A,\N,\N,11/11,Benign,\N,intron_variant,2.969,0.0363,1KG_AFR_AF,TSPEAR
501200,21:45923435:T>G,NM_144991.2:c.1856+1228A>C,\N,\N,11/11,Unknown significance,\N,intron_variant,5.653,\N,\N,TSPEAR
501201,21:45923446:T>G,NM_144991.2:c.1856+1217A>C,\N,\N,11/11,Unknown significance,\N,intron_variant,3.299,\N,\N,TSPEAR
501202,21:45923451:TG>T,NM_144991.2:c.1856+1211del,\N,\N,11/11,Unknown significance,\N,intron_variant,\N,0.002,1KG_EUR_AF,TSPEAR
501203,21:45923468:C>T,NM_144991.2:c.1856+1195G>A,\N,\N,11/11,Benign,\N,intron_variant,5.447,0.0053,1KG_AFR_AF,TSPEAR
501204,21:45923480:AG>A,NM_144991.2:c.1856+1182del,\N,\N,11/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
501205,21:45923481:G>T,NM_144991.2:c.1856+1182C>A,\N,\N,11/11,Unknown significance,\N,intron_variant,0.052,0.003,1KG_EAS_AF,TSPEAR
501206,21:45923506:G>C,NM_144991.2:c.1856+1157C>G,\N,\N,11/11,Unknown significance,\N,intron_variant,2.289,0.001,1KG_EUR_AF,TSPEAR
501207,21:45923527:G>C,NM_144991.2:c.1856+1136C>G,\N,\N,11/11,Unknown significance,\N,intron_variant,1.403,0.001,1KG_SAS_AF,TSPEAR
501208,21:45923536:C>T,NM_144991.2:c.1856+1127G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,5.083,\N,\N,TSPEAR
501209,21:45923556:C>G,NM_144991.2:c.1856+1107G>C,\N,\N,11/11,Unknown significance,\N,intron_variant,3.804,\N,\N,TSPEAR
501210,21:45923583:C>T,NM_144991.2:c.1856+1080G>A,\N,\N,11/11,Benign,\N,intron_variant,5.379,0.028,1KG_AFR_AF,TSPEAR
501211,21:45923584:G>A,NM_144991.2:c.1856+1079C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,4.706,0.001,1KG_EAS_AF,TSPEAR
501212,21:45923589:C>T,NM_144991.2:c.1856+1074G>A,\N,\N,11/11,Benign,\N,intron_variant,4.783,0.0068,1KG_AFR_AF,TSPEAR
501213,21:45923599:T>A,NM_144991.2:c.1856+1064A>T,\N,\N,11/11,Unknown significance,\N,intron_variant,1.757,0.001,1KG_EAS_AF,TSPEAR
501214,21:45923601:G>A,NM_144991.2:c.1856+1062C>T,\N,\N,11/11,Benign,\N,intron_variant,5.434,0.0719,1KG_AFR_AF,TSPEAR
501215,21:45923603:C>G,NM_144991.2:c.1856+1060G>C,\N,\N,11/11,Unknown significance,\N,intron_variant,3.03,\N,\N,TSPEAR
501216,21:45923603:C>T,NM_144991.2:c.1856+1060G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,4.766,0.003,1KG_AFR_AF,TSPEAR
501217,21:45923629:C>T,NM_144991.2:c.1856+1034G>A,\N,\N,11/11,Benign,\N,intron_variant,6.924,0.0174,1KG_AFR_AF,TSPEAR
501218,21:45923647:G>A,NM_144991.2:c.1856+1016C>T,\N,\N,11/11,Benign,\N,intron_variant,3.667,0.0129,1KG_AFR_AF,TSPEAR
501219,21:45923648:G>GC,NM_144991.2:c.1856+1014_1856+1015insG,\N,\N,11/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
501220,21:45923649:G>C,NM_144991.2:c.1856+1014C>G,\N,\N,11/11,Benign,\N,intron_variant,1.331,0.0151,1KG_AFR_AF,TSPEAR
501221,21:45923654:A>G,NM_144991.2:c.1856+1009T>C,\N,\N,11/11,Unknown significance,\N,intron_variant,4.868,0.001,1KG_EAS_AF,TSPEAR
501222,21:45923673:G>T,NM_144991.2:c.1856+990C>A,\N,\N,11/11,Benign,\N,intron_variant,2.321,0.4583,1KG_EAS_AF,TSPEAR
501223,21:45923674:C>T,NM_144991.2:c.1856+989G>A,\N,\N,11/11,Benign,\N,intron_variant,3.246,0.0113,1KG_AFR_AF,TSPEAR
501224,21:45923675:T>C,NM_144991.2:c.1856+988A>G,\N,\N,11/11,Unknown significance,\N,intron_variant,0.199,\N,\N,TSPEAR
501225,21:45923691:T>A,NM_144991.2:c.1856+972A>T,\N,\N,11/11,Benign,\N,intron_variant,0.498,0.0113,1KG_AFR_AF,TSPEAR
501226,21:45923722:G>A,NM_144991.2:c.1856+941C>T,\N,\N,11/11,Benign,\N,intron_variant,3.391,0.1905,1KG_EAS_AF,TSPEAR
501227,21:45923740:G>C,NM_144991.2:c.1856+923C>G,\N,\N,11/11,Unknown significance,\N,intron_variant,1.312,0.001,1KG_SAS_AF,TSPEAR
501228,21:45923744:G>A,NM_144991.2:c.1856+919C>T,\N,\N,11/11,Benign,\N,intron_variant,5.555,0.0102,1KG_SAS_AF,TSPEAR
501229,21:45923769:G>A,NM_144991.2:c.1856+894C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,3.518,\N,\N,TSPEAR
501230,21:45923769:G>T,NM_144991.2:c.1856+894C>A,\N,\N,11/11,Benign,\N,intron_variant,1.344,0.0501,1KG_SAS_AF,TSPEAR
501231,21:45923800:C>T,NM_144991.2:c.1856+863G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,6.382,0.001,1KG_EAS_AF,TSPEAR
501232,21:45923802:C>T,NM_144991.2:c.1856+861G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,5.884,0.0015,1KG_AFR_AF,TSPEAR
501233,21:45923813:C>T,NM_144991.2:c.1856+850G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,5.684,0.001,1KG_SAS_AF,TSPEAR
501234,21:45923814:G>A,NM_144991.2:c.1856+849C>T,\N,\N,11/11,Benign,\N,intron_variant,5.91,0.0424,1KG_AFR_AF,TSPEAR
501235,21:45923839:G>A,NM_144991.2:c.1856+824C>T,\N,\N,11/11,Benign,\N,intron_variant,2.015,0.0113,1KG_AFR_AF,TSPEAR
501236,21:45923841:C>T,NM_144991.2:c.1856+822G>A,\N,\N,11/11,Benign,\N,intron_variant,4.801,0.0113,1KG_AFR_AF,TSPEAR
501237,21:45923842:C>T,NM_144991.2:c.1856+821G>A,\N,\N,11/11,Benign,\N,intron_variant,3.035,0.0113,1KG_AFR_AF,TSPEAR
501238,21:45923843:G>A,NM_144991.2:c.1856+820C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,3.22,0.0014,1KG_AMR_AF,TSPEAR
501239,21:45923845:A>C,NM_144991.2:c.1856+818T>G,\N,\N,11/11,Benign,\N,intron_variant,0.619,0.0121,1KG_AFR_AF,TSPEAR
501240,21:45923846:G>C,NM_144991.2:c.1856+817C>G,\N,\N,11/11,Benign,\N,intron_variant,0.255,0.0121,1KG_AFR_AF,TSPEAR
501241,21:45923848:T>C,NM_144991.2:c.1856+815A>G,\N,\N,11/11,Benign,\N,intron_variant,0.047,0.0113,1KG_AFR_AF,TSPEAR
501242,21:45923858:T>A,NM_144991.2:c.1856+805A>T,\N,\N,11/11,Benign,\N,intron_variant,4.949,0.0325,1KG_AFR_AF,TSPEAR
501243,21:45923860:G>A,NM_144991.2:c.1856+803C>T,\N,\N,11/11,Benign,\N,intron_variant,2.562,0.034,1KG_AFR_AF,TSPEAR
501244,21:45923861:GC>G,NM_144991.2:c.1856+801del,\N,\N,11/11,Unknown significance,\N,intron_variant,0.104,\N,\N,TSPEAR
501245,21:45923863:G>A,NM_144991.2:c.1856+800C>T,\N,\N,11/11,Benign,\N,intron_variant,2.988,0.098,1KG_AMR_AF,TSPEAR
501246,21:45923886:A>G,NM_144991.2:c.1856+777T>C,\N,\N,11/11,Unknown significance,\N,intron_variant,0.387,0.002,1KG_EAS_AF,TSPEAR
501247,21:45923887:G>T,NM_144991.2:c.1856+776C>A,\N,\N,11/11,Unknown significance,\N,intron_variant,2.347,\N,\N,TSPEAR
501248,21:45923889:C>T,NM_144991.2:c.1856+774G>A,\N,\N,11/11,Benign,\N,intron_variant,5.801,0.0268,1KG_EAS_AF,TSPEAR
501249,21:45923910:A>G,NM_144991.2:c.1856+753T>C,\N,\N,11/11,Benign,\N,intron_variant,4.713,0.1278,1KG_AFR_AF,TSPEAR
501250,21:45923920:G>C,NM_144991.2:c.1856+743C>G,\N,\N,11/11,Unknown significance,\N,intron_variant,0.667,0.003,1KG_AFR_AF,TSPEAR
501251,21:45923932:A>C,NM_144991.2:c.1856+731T>G,\N,\N,11/11,Unknown significance,\N,intron_variant,1.479,0.0038,1KG_AFR_AF,TSPEAR
501252,21:45923934:T>C,NM_144991.2:c.1856+729A>G,\N,\N,11/11,Unknown significance,\N,intron_variant,1.681,\N,\N,TSPEAR
501253,21:45923942:G>A,NM_144991.2:c.1856+721C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,1.673,0.001,1KG_EAS_AF,TSPEAR
501254,21:45923950:C>T,NM_144991.2:c.1856+713G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,2.638,0.0008,1KG_AFR_AF,TSPEAR
501255,21:45923954:G>C,NM_144991.2:c.1856+709C>G,\N,\N,11/11,Unknown significance,\N,intron_variant,0.529,0.0015,1KG_AFR_AF,TSPEAR
501256,21:45923954:G>T,NM_144991.2:c.1856+709C>A,\N,\N,11/11,Unknown significance,\N,intron_variant,0.936,\N,\N,TSPEAR
501257,21:45923955:G>C,NM_144991.2:c.1856+708C>G,\N,\N,11/11,Unknown significance,\N,intron_variant,0.006,0.001,1KG_EAS_AF,TSPEAR
501258,21:45923995:G>T,NM_144991.2:c.1856+668C>A,\N,\N,11/11,Unknown significance,\N,intron_variant,2.151,0.003,1KG_AFR_AF,TSPEAR
501259,21:45924000:G>T,NM_144991.2:c.1856+663C>A,\N,\N,11/11,Unknown significance,\N,intron_variant,3.972,0.003,1KG_AFR_AF,TSPEAR
501260,21:45924002:G>A,NM_144991.2:c.1856+661C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,4.736,\N,\N,TSPEAR
501261,21:45924003:A>C,NM_144991.2:c.1856+660T>G,\N,\N,11/11,Unknown significance,\N,intron_variant,2.696,\N,\N,TSPEAR
501262,21:45924004:G>T,NM_144991.2:c.1856+659C>A,\N,\N,11/11,Unknown significance,\N,intron_variant,2.696,\N,\N,TSPEAR
501263,21:45924010:C>T,NM_144991.2:c.1856+653G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,5.278,0.0008,1KG_AFR_AF,TSPEAR
501264,21:45924016:C>T,NM_144991.2:c.1856+647G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,5.828,0.003,1KG_AFR_AF,TSPEAR
501265,21:45924043:C>T,NM_144991.2:c.1856+620G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,4.518,0.0008,1KG_AFR_AF,TSPEAR
501266,21:45924057:C>T,NM_144991.2:c.1856+606G>A,\N,\N,11/11,Benign,\N,intron_variant,7.084,0.0204,1KG_AFR_AF,TSPEAR
501267,21:45924058:G>A,NM_144991.2:c.1856+605C>T,\N,\N,11/11,Benign,\N,intron_variant,6.065,0.0164,1KG_SAS_AF,TSPEAR
501268,21:45924081:G>A,NM_144991.2:c.1856+582C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,5.526,0.001,1KG_EUR_AF,TSPEAR
501269,21:45924104:C>T,NM_144991.2:c.1856+559G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,6.456,0.002,1KG_EAS_AF,TSPEAR
501270,21:45924105:G>A,NM_144991.2:c.1856+558C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,5.185,\N,\N,TSPEAR
501271,21:45924111:G>A,NM_144991.2:c.1856+552C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,2.806,0.001,1KG_EUR_AF,TSPEAR
501272,21:45924125:G>T,NM_144991.2:c.1856+538C>A,\N,\N,11/11,Unknown significance,\N,intron_variant,1.482,0.0038,1KG_AFR_AF,TSPEAR
501273,21:45924127:G>T,NM_144991.2:c.1856+536C>A,\N,\N,11/11,Benign,\N,intron_variant,0.976,0.3839,1KG_EAS_AF,TSPEAR
501274,21:45924135:C>T,NM_144991.2:c.1856+528G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,7.15,0.0015,1KG_AFR_AF,TSPEAR
501275,21:45924148:T>A,NM_144991.2:c.1856+515A>T,\N,\N,11/11,Unknown significance,\N,intron_variant,6.261,\N,\N,TSPEAR
501276,21:45924153:G>A,NM_144991.2:c.1856+510C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,5.839,0.003,1KG_EAS_AF,TSPEAR
501277,21:45924169:G>A,NM_144991.2:c.1856+494C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,6.537,0.001,1KG_EUR_AF|1KG_SAS_AF,TSPEAR
501278,21:45924171:A>G,NM_144991.2:c.1856+492T>C,\N,\N,11/11,Unknown significance,\N,intron_variant,6.735,0.001,1KG_EAS_AF|1KG_EUR_AF|1KG_SAS_AF,TSPEAR
501279,21:45924178:C>T,NM_144991.2:c.1856+485G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,1.809,0.001,1KG_EUR_AF|1KG_SAS_AF,TSPEAR
501280,21:45924179:G>A,NM_144991.2:c.1856+484C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,6.689,0.001,1KG_EUR_AF,TSPEAR
501281,21:45924190:G>C,NM_144991.2:c.1856+473C>G,\N,\N,11/11,Unknown significance,\N,intron_variant,1.82,0.0023,1KG_AFR_AF,TSPEAR
501282,21:45924198:G>A,NM_144991.2:c.1856+465C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,3.737,\N,\N,TSPEAR
501283,21:45924231:G>A,NM_144991.2:c.1856+432C>T,\N,\N,11/11,Benign,\N,intron_variant,2.13,0.005,1KG_EAS_AF,TSPEAR
501284,21:45924242:G>A,NM_144991.2:c.1856+421C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,1.518,\N,\N,TSPEAR
501285,21:45924254:T>G,NM_144991.2:c.1856+409A>C,\N,\N,11/11,Unknown significance,\N,intron_variant,2.751,0.002,1KG_EAS_AF,TSPEAR
501286,21:45924276:G>C,NM_144991.2:c.1856+387C>G,\N,\N,11/11,Benign,\N,intron_variant,0.23,0.0212,1KG_AFR_AF,TSPEAR
501287,21:45924286:C>CG,NM_144991.2:c.1856+376dup,\N,\N,11/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
501288,21:45924301:T>A,NM_144991.2:c.1856+362A>T,\N,\N,11/11,Benign,\N,intron_variant,1.039,0.005,1KG_EAS_AF,TSPEAR
501289,21:45924305:G>A,NM_144991.2:c.1856+358C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,5.1,\N,\N,TSPEAR
501290,21:45924314:T>C,NM_144991.2:c.1856+349A>G,\N,\N,11/11,Unknown significance,\N,intron_variant,0.171,\N,\N,TSPEAR
501291,21:45924321:A>G,NM_144991.2:c.1856+342T>C,\N,\N,11/11,Benign,\N,intron_variant,1.696,0.031,1KG_AFR_AF,TSPEAR
501292,21:45924330:A>T,NM_144991.2:c.1856+333T>A,\N,\N,11/11,Unknown significance,\N,intron_variant,0.24,\N,\N,TSPEAR
501293,21:45924333:GT>G,NM_144991.2:c.1856+329del,\N,\N,11/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
501294,21:45924344:A>G,NM_144991.2:c.1856+319T>C,\N,\N,11/11,Unknown significance,\N,intron_variant,3.048,\N,\N,TSPEAR
501295,21:45924346:G>T,NM_144991.2:c.1856+317C>A,\N,\N,11/11,Benign,\N,intron_variant,0.488,0.1407,1KG_AFR_AF,TSPEAR
501296,21:45924351:T>G,NM_144991.2:c.1856+312A>C,\N,\N,11/11,Unknown significance,\N,intron_variant,1.647,\N,\N,TSPEAR
501297,21:45924358:G>A,NM_144991.2:c.1856+305C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,0.185,\N,\N,TSPEAR
501298,21:45924362:G>A,NM_144991.2:c.1856+301C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,3.941,0.0008,1KG_AFR_AF,TSPEAR
501299,21:45924367:CG>C,NM_144991.2:c.1856+295del,\N,\N,11/11,Unknown significance,\N,intron_variant,\N,0.002,1KG_EAS_AF,TSPEAR
501300,21:45924368:G>A,NM_144991.2:c.1856+295C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,2.994,0.0031,1KG_SAS_AF,TSPEAR
501301,21:45924393:G>T,NM_144991.2:c.1856+270C>A,\N,\N,11/11,Unknown significance,\N,intron_variant,0.459,\N,\N,TSPEAR
501302,21:45924398:G>T,NM_144991.2:c.1856+265C>A,\N,\N,11/11,Unknown significance,\N,intron_variant,0.892,\N,\N,TSPEAR
501303,21:45924405:G>A,NM_144991.2:c.1856+258C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,1.554,\N,\N,TSPEAR
501304,21:45924408:C>A,NM_144991.2:c.1856+255G>T,\N,\N,11/11,Unknown significance,\N,intron_variant,3.192,\N,\N,TSPEAR
501305,21:45924408:C>T,NM_144991.2:c.1856+255G>A,\N,\N,11/11,Benign,\N,intron_variant,3.231,0.031,1KG_AFR_AF,TSPEAR
501306,21:45924411:C>T,NM_144991.2:c.1856+252G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,3.398,0.002,1KG_EAS_AF,TSPEAR
501307,21:45924576:G>A,NM_144991.2:c.1856+87C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,3.212,0.001,1KG_EAS_AF,TSPEAR
501308,21:45924593:G>A,NM_144991.2:c.1856+70C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,5.704,\N,\N,TSPEAR
501309,21:45924596:C>T,NM_144991.2:c.1856+67G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,0.882,\N,\N,TSPEAR
501310,21:45924597:G>A,NM_144991.2:c.1856+66C>T,\N,\N,11/11,Benign,\N,intron_variant,4.743,0.006,1KG_EUR_AF,TSPEAR
501311,21:45924612:ACAGT>TCG,NM_144991.2:c.1856+47_1856+51delinsCGA,\N,\N,11/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
501312,21:45924615:G>A,NM_144991.2:c.1856+48C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,1.436,0.000181291,EXAC_AMR_AF,TSPEAR
501313,21:45924627:GGCTCTGGGAGGAGGCCGGCCTCGGCA>G,NM_144991.2:c.1856+10_1856+35del,\N,\N,11/11,Unknown significance,\N,intron_variant,7.554,\N,\N,TSPEAR
501314,21:45924628:G>T,NM_144991.2:c.1856+35C>A,\N,\N,11/11,Benign,\N,intron_variant,0.925,0.006,1KG_EAS_AF,TSPEAR
501315,21:45924629:C>T,NM_144991.2:c.1856+34G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,0.519,0.000453926,EVS_AA_AF,TSPEAR
501316,21:45924630:T>C,NM_144991.2:c.1856+33A>G,\N,\N,11/11,Unknown significance,\N,intron_variant,0.971,0.0000155473,EXAC_NFE_AF,TSPEAR
501317,21:45924631:C>T,NM_144991.2:c.1856+32G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,1.524,0.00011976,EXAC_EAS_AF,TSPEAR
501318,21:45924633:G>T,NM_144991.2:c.1856+30C>A,\N,\N,11/11,Unknown significance,\N,intron_variant,5.18,0.003,1KG_EAS_AF,TSPEAR
501319,21:45924634:G>A,NM_144991.2:c.1856+29C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,6.789,0.000106519,EXAC_AFR_AF,TSPEAR
501320,21:45924638:G>A,NM_144991.2:c.1856+25C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,8.319,0.00015328,EXAC_FIN_AF,TSPEAR
501321,21:45924640:G>A,NM_144991.2:c.1856+23C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,3.939,0.000211015,EXAC_AFR_AF,TSPEAR
501322,21:45924643:C>T,NM_144991.2:c.1856+20G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,1.434,0.000116279,EVS_EA_AF,TSPEAR
501323,21:45924644:G>A,NM_144991.2:c.1856+19C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,2.274,0.00480769,EXAC_EAS_AF,TSPEAR
501324,21:45924649:C>A,NM_144991.2:c.1856+14G>T,\N,\N,11/11,Unknown significance,\N,intron_variant,3.056,0.0000305465,EXAC_NFE_AF,TSPEAR
501325,21:45924649:C>T,NM_144991.2:c.1856+14G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,2.315,0.000244372,EXAC_NFE_AF,TSPEAR
501326,21:45924650:G>A,NM_144991.2:c.1856+13C>T,\N,\N,11/11,Unknown significance,\N,intron_variant,5.835,0.0000457289,EXAC_NFE_AF,TSPEAR
501327,21:45924652:C>T,NM_144991.2:c.1856+11G>A,\N,\N,11/11,Unknown significance,\N,intron_variant,7.578,0.000226963,EVS_AA_AF,TSPEAR
501328,21:45924663:C>CTG,NM_144991.2:c.1854_1855dup,NP_659428.2:p.Arg619ThrfsTer49,11/12,\N,Unknown significance,\N,frameshift_variant&splice_region_variant,35,0.0000151108,EXAC_NFE_AF,TSPEAR
501329,21:45924665:G>A,NM_144991.2:c.1854C>T,NP_659428.2:p.Tyr618=,11/12,\N,Unknown significance,\N,splice_region_variant&synonymous_variant,10.64,0.001,1KG_SAS_AF,TSPEAR
501330,21:45924667:A>T,NM_144991.2:c.1852T>A,NP_659428.2:p.Tyr618Asn,11/12,\N,Unknown significance,\N,missense_variant,29.3,0.000030185,EXAC_NFE_AF,TSPEAR
501331,21:45924669:A>G,NM_144991.2:c.1850T>C,NP_659428.2:p.Ile617Thr,11/12,\N,Unknown significance,\N,missense_variant,27.4,0.001,1KG_SAS_AF,TSPEAR
501332,21:45924673:T>C,NM_144991.2:c.1846A>G,NP_659428.2:p.Ile616Val,11/12,\N,Likely benign,\N,missense_variant,7.336,0.0000150752,EXAC_NFE_AF,TSPEAR
501333,21:45924680:C>T,NM_144991.2:c.1839G>A,NP_659428.2:p.Val613=,11/12,\N,Unknown significance,\N,synonymous_variant,11.21,0.000086881,EXAC_AMR_AF,TSPEAR
501334,21:45924683:C>A,NM_144991.2:c.1836G>T,NP_659428.2:p.Ser612=,11/12,\N,Benign,\N,synonymous_variant,16.66,0.0213909,EXAC_AFR_AF,TSPEAR
501335,21:45924683:C>T,NM_144991.2:c.1836G>A,NP_659428.2:p.Ser612=,11/12,\N,Unknown significance,\N,synonymous_variant,13.24,0.00030447,EXAC_SAS_AF,TSPEAR
501336,21:45924684:G>A,NM_144991.2:c.1835C>T,NP_659428.2:p.Ser612Leu,11/12,\N,Likely benign,\N,missense_variant,16.06,0.0000300915,EXAC_NFE_AF,TSPEAR
501337,21:45924687:A>G,NM_144991.2:c.1832T>C,NP_659428.2:p.Phe611Ser,11/12,\N,Unknown significance,\N,missense_variant,24,0.0000608347,EXAC_SAS_AF,TSPEAR
501338,21:45924689:G>A,NM_144991.2:c.1830C>T,NP_659428.2:p.Thr610=,11/12,\N,Unknown significance,\N,synonymous_variant,6.401,0.0014,1KG_AMR_AF,TSPEAR
501339,21:45924690:G>C,NM_144991.2:c.1829C>G,NP_659428.2:p.Thr610Ser,11/12,\N,Likely benign,\N,missense_variant,6.663,0.000116279,EVS_EA_AF,TSPEAR
501340,21:45924692:A>G,NM_144991.2:c.1827T>C,NP_659428.2:p.Arg609=,11/12,\N,Unknown significance,\N,synonymous_variant,0.018,0.0000867453,EXAC_AMR_AF,TSPEAR
501341,21:45924693:C>T,NM_144991.2:c.1826G>A,NP_659428.2:p.Arg609His,11/12,\N,Likely pathogenic,Schizophrenia,missense_variant,12.34,0.000232558,EVS_EA_AF,TSPEAR
501342,21:45924694:G>A,NM_144991.2:c.1825C>T,NP_659428.2:p.Arg609Cys,11/12,\N,Likely benign,\N,missense_variant,23.8,0.0015,1KG_AFR_AF,TSPEAR
501343,21:45924696:C>A,NM_144991.2:c.1823G>T,NP_659428.2:p.Gly608Val,11/12,\N,Unknown significance,\N,missense_variant,25.6,0.0000300553,EXAC_NFE_AF,TSPEAR
501344,21:45924700:C>T,NM_144991.2:c.1819G>A,NP_659428.2:p.Asp607Asn,11/12,\N,Unknown significance,\N,missense_variant,23.8,0.001,1KG_EAS_AF,TSPEAR
501345,21:45924702:A>G,NM_144991.2:c.1817T>C,NP_659428.2:p.Phe606Ser,11/12,\N,Unknown significance,\N,missense_variant,15.94,0.0000150227,EXAC_NFE_AF,TSPEAR
501346,21:45924714:A>G,NM_144991.2:c.1805T>C,NP_659428.2:p.Val602Ala,11/12,\N,Unknown significance,\N,missense_variant,19.79,0.000182194,EXAC_SAS_AF,TSPEAR
501347,21:45924716:C>T,NM_144991.2:c.1803G>A,NP_659428.2:p.Val601=,11/12,\N,Unknown significance,\N,synonymous_variant,9.076,\N,\N,TSPEAR
501348,21:45924718:C>T,NM_144991.2:c.1801G>A,NP_659428.2:p.Val601Met,11/12,\N,Unknown significance,\N,missense_variant,27.8,0.0000300318,EXAC_NFE_AF,TSPEAR
501349,21:45924720:A>T,NM_144991.2:c.1799T>A,NP_659428.2:p.Leu600Gln,11/12,\N,Unknown significance,\N,missense_variant,26.5,0.0000150155,EXAC_NFE_AF,TSPEAR
501350,21:45924728:ATCT>A,NM_144991.2:c.1788_1790del,NP_659428.2:p.Glu596del,11/12,\N,Unknown significance,\N,inframe_deletion,20.3,0.00034638,EXAC_AMR_AF,TSPEAR
501351,21:45924731:T>A,NM_144991.2:c.1788A>T,NP_659428.2:p.Glu596Asp,11/12,\N,Unknown significance,\N,missense_variant,13.82,0.0000300291,EXAC_NFE_AF,TSPEAR
501352,21:45924733:C>T,NM_144991.2:c.1786G>A,NP_659428.2:p.Glu596Lys,11/12,\N,Unknown significance,\N,missense_variant,24.6,0.00034638,EXAC_AMR_AF,TSPEAR
501353,21:45924734:T>G,NM_144991.2:c.1785A>C,NP_659428.2:p.Gly595=,11/12,\N,Unknown significance,\N,synonymous_variant,6.412,0.0000150141,EXAC_NFE_AF,TSPEAR
501354,21:45924735:CCCA>C,NM_144991.2:c.1781_1783del,NP_659428.2:p.Val594del,11/12,\N,Unknown significance,\N,inframe_deletion,21.6,\N,\N,TSPEAR
501355,21:45924740:C>T,NM_144991.2:c.1779G>A,NP_659428.2:p.Ser593=,11/12,\N,Benign,\N,synonymous_variant,16.72,0.0159,1KG_AFR_AF,TSPEAR
501356,21:45924741:G>A,NM_144991.2:c.1778C>T,NP_659428.2:p.Ser593Leu,11/12,\N,Unknown significance,\N,missense_variant,25.7,0.00181571,EVS_AA_AF,TSPEAR
501357,21:45924749:C>T,NM_144991.2:c.1770G>A,NP_659428.2:p.Glu590=,11/12,\N,Unknown significance,\N,synonymous_variant,13.37,0.0000601088,EXAC_NFE_AF,TSPEAR
501358,21:45924750:T>C,NM_144991.2:c.1769A>G,NP_659428.2:p.Glu590Gly,11/12,\N,Unknown significance,\N,missense_variant,32,0.000115714,EXAC_EAS_AF,TSPEAR
501359,21:45924764:A>C,NM_144991.2:c.1755T>G,NP_659428.2:p.Ser585Arg,11/12,\N,Unknown significance,\N,missense_variant&splice_region_variant,22.8,\N,\N,TSPEAR
501360,21:45924771:G>A,NM_144991.2:c.1755-7C>T,\N,\N,10/11,Benign,\N,splice_region_variant&intron_variant,1.045,0.00545124,EXAC_FIN_AF,TSPEAR
501361,21:45924781:G>T,NM_144991.2:c.1755-17C>A,\N,\N,10/11,Unknown significance,\N,intron_variant,1.698,0.00010016,EXAC_AFR_AF,TSPEAR
501362,21:45924784:G>A,NM_144991.2:c.1755-20C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,5.053,0.000116279,EVS_EA_AF,TSPEAR
501363,21:45924786:T>TATTAGG,NM_144991.2:c.1755-28_1755-23dup,\N,\N,10/11,Unknown significance,\N,intron_variant,0.197,0.0000302783,EXAC_NFE_AF,TSPEAR
501364,21:45924788:T>C,NM_144991.2:c.1755-24A>G,\N,\N,10/11,Unknown significance,\N,intron_variant,2.017,0.000226963,EVS_AA_AF,TSPEAR
501365,21:45924795:A>G,NM_144991.2:c.1755-31T>C,\N,\N,10/11,Unknown significance,\N,intron_variant,2.779,\N,\N,TSPEAR
501366,21:45924803:CA>C,NM_144991.2:c.1755-40del,\N,\N,10/11,Unknown significance,\N,intron_variant,1.477,0.0000152411,EXAC_NFE_AF,TSPEAR
501367,21:45924804:A>G,NM_144991.2:c.1755-40T>C,\N,\N,10/11,Unknown significance,\N,intron_variant,0.241,0.000117619,EXAC_EAS_AF,TSPEAR
501368,21:45924806:C>T,NM_144991.2:c.1755-42G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,0.4,0.001,1KG_EAS_AF,TSPEAR
501369,21:45924807:G>A,NM_144991.2:c.1755-43C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,1.853,0.002,1KG_EAS_AF,TSPEAR
501370,21:45924807:G>T,NM_144991.2:c.1755-43C>A,\N,\N,10/11,Unknown significance,\N,intron_variant,0.797,0.0000153003,EXAC_NFE_AF,TSPEAR
501371,21:45924813:G>A,NM_144991.2:c.1755-49C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,1.951,0.0000153974,EXAC_NFE_AF,TSPEAR
501372,21:45924826:G>A,NM_144991.2:c.1755-62C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,1.235,0.002,1KG_SAS_AF,TSPEAR
501373,21:45924829:C>T,NM_144991.2:c.1755-65G>A,\N,\N,10/11,Benign,\N,intron_variant,2.256,0.0091,1KG_AFR_AF,TSPEAR
501374,21:45924863:C>T,NM_144991.2:c.1755-99G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,1.086,\N,\N,TSPEAR
501375,21:45924864:G>A,NM_144991.2:c.1755-100C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,2.061,0.001,1KG_SAS_AF,TSPEAR
501376,21:45924907:T>C,NM_144991.2:c.1755-143A>G,\N,\N,10/11,Unknown significance,\N,intron_variant,4.421,\N,\N,TSPEAR
501377,21:45924931:T>C,NM_144991.2:c.1755-167A>G,\N,\N,10/11,Unknown significance,\N,intron_variant,2.353,0.0014,1KG_AMR_AF,TSPEAR
501378,21:45924944:T>G,NM_144991.2:c.1755-180A>C,\N,\N,10/11,Unknown significance,\N,intron_variant,2.905,0.002,1KG_EUR_AF,TSPEAR
501379,21:45924985:G>A,NM_144991.2:c.1755-221C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,4.975,0.001,1KG_EUR_AF,TSPEAR
501380,21:45924992:C>T,NM_144991.2:c.1755-228G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,1.19,0.0029,1KG_AMR_AF,TSPEAR
501381,21:45925009:T>A,NM_144991.2:c.1755-245A>T,\N,\N,10/11,Benign,\N,intron_variant,4.14,0.006,1KG_EUR_AF,TSPEAR
501382,21:45925022:C>T,NM_144991.2:c.1755-258G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,0.73,0.001,1KG_EUR_AF,TSPEAR
501383,21:45925038:G>A,NM_144991.2:c.1755-274C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,0.071,0.001,1KG_SAS_AF,TSPEAR
501384,21:45925058:T>C,NM_144991.2:c.1755-294A>G,\N,\N,10/11,Unknown significance,\N,intron_variant,0.372,\N,\N,TSPEAR
501385,21:45925086:C>T,NM_144991.2:c.1755-322G>A,\N,\N,10/11,Benign,\N,intron_variant,1.051,0.0204,1KG_AFR_AF,TSPEAR
501386,21:45925087:G>A,NM_144991.2:c.1755-323C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,0.831,0.001,1KG_SAS_AF,TSPEAR
501387,21:45925089:G>A,NM_144991.2:c.1755-325C>T,\N,\N,10/11,Benign,\N,intron_variant,2.845,0.0242,1KG_AFR_AF,TSPEAR
501388,21:45925109:G>A,NM_144991.2:c.1755-345C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,0.405,0.002,1KG_SAS_AF,TSPEAR
501389,21:45925116:C>T,NM_144991.2:c.1755-352G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,0.731,0.001,1KG_EUR_AF,TSPEAR
501390,21:45925118:C>T,NM_144991.2:c.1755-354G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,0.975,0.002,1KG_EUR_AF,TSPEAR
501391,21:45925122:C>T,NM_144991.2:c.1755-358G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,0.534,0.0008,1KG_AFR_AF,TSPEAR
501392,21:45925134:G>T,NM_144991.2:c.1755-370C>A,\N,\N,10/11,Benign,\N,intron_variant,0.921,0.0113,1KG_AFR_AF,TSPEAR
501393,21:45925162:A>G,NM_144991.2:c.1755-398T>C,\N,\N,10/11,Unknown significance,\N,intron_variant,2.039,0.001,1KG_EAS_AF,TSPEAR
501394,21:45925198:G>C,NM_144991.2:c.1755-434C>G,\N,\N,10/11,Unknown significance,\N,intron_variant,0.242,0.0008,1KG_AFR_AF,TSPEAR
501395,21:45925216:C>T,NM_144991.2:c.1755-452G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,5.767,\N,\N,TSPEAR
501396,21:45925230:G>A,NM_144991.2:c.1755-466C>T,\N,\N,10/11,Benign,\N,intron_variant,4.931,0.0182,1KG_AFR_AF,TSPEAR
501397,21:45925239:G>C,NM_144991.2:c.1755-475C>G,\N,\N,10/11,Unknown significance,\N,intron_variant,1.817,\N,\N,TSPEAR
501398,21:45925250:C>A,NM_144991.2:c.1755-486G>T,\N,\N,10/11,Unknown significance,\N,intron_variant,4.142,0.0038,1KG_AFR_AF,TSPEAR
501399,21:45925270:T>G,NM_144991.2:c.1755-506A>C,\N,\N,10/11,Unknown significance,\N,intron_variant,1.385,0.003,1KG_EAS_AF,TSPEAR
501400,21:45925285:T>A,NM_144991.2:c.1755-521A>T,\N,\N,10/11,Unknown significance,\N,intron_variant,2.264,\N,\N,TSPEAR
501401,21:45925290:A>G,NM_144991.2:c.1755-526T>C,\N,\N,10/11,Unknown significance,\N,intron_variant,0.635,0.001,1KG_EUR_AF,TSPEAR
501402,21:45925296:T>C,NM_144991.2:c.1755-532A>G,\N,\N,10/11,Benign,\N,intron_variant,2.248,0.0219,1KG_AFR_AF,TSPEAR
501403,21:45925335:A>AG,NM_144991.2:c.1755-572dup,\N,\N,10/11,Unknown significance,\N,intron_variant,0.286,0.0041,1KG_SAS_AF,TSPEAR
501404,21:45925355:T>C,NM_144991.2:c.1755-591A>G,\N,\N,10/11,Unknown significance,\N,intron_variant,0.783,0.001,1KG_EUR_AF,TSPEAR
501405,21:45925366:G>T,NM_144991.2:c.1755-602C>A,\N,\N,10/11,Unknown significance,\N,intron_variant,0.637,\N,\N,TSPEAR
501406,21:45925393:C>T,NM_144991.2:c.1755-629G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,6.94,\N,\N,TSPEAR
501407,21:45925412:C>T,NM_144991.2:c.1755-648G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,3.623,\N,\N,TSPEAR
501408,21:45925450:T>C,NM_144991.2:c.1755-686A>G,\N,\N,10/11,Unknown significance,\N,intron_variant,1.34,\N,\N,TSPEAR
501409,21:45925451:C>T,NM_144991.2:c.1755-687G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,3.912,\N,\N,TSPEAR
501410,21:45925459:C>T,NM_144991.2:c.1755-695G>A,\N,\N,10/11,Benign,\N,intron_variant,4.434,0.084,1KG_AFR_AF,TSPEAR
501411,21:45925462:C>G,NM_144991.2:c.1755-698G>C,\N,\N,10/11,Benign,\N,intron_variant,2.238,0.0129,1KG_AFR_AF,TSPEAR
501412,21:45925464:C>T,NM_144991.2:c.1755-700G>A,\N,\N,10/11,Benign,\N,intron_variant,4.347,0.0484,1KG_AFR_AF,TSPEAR
501413,21:45925487:G>A,NM_144991.2:c.1755-723C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,3.64,0.001,1KG_SAS_AF,TSPEAR
501414,21:45925542:C>T,NM_144991.2:c.1755-778G>A,\N,\N,10/11,Benign,\N,intron_variant,6.123,0.0051,1KG_SAS_AF,TSPEAR
501415,21:45925546:C>T,NM_144991.2:c.1755-782G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,5.181,0.002,1KG_EAS_AF,TSPEAR
501416,21:45925581:T>G,NM_144991.2:c.1755-817A>C,\N,\N,10/11,Unknown significance,\N,intron_variant,3.317,\N,\N,TSPEAR
501417,21:45925626:G>A,NM_144991.2:c.1755-862C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,3.851,0.001,1KG_EAS_AF,TSPEAR
501418,21:45925631:CCTTT>C,NM_144991.2:c.1755-871_1755-868del,\N,\N,10/11,Benign,\N,intron_variant,5.467,0.1089,1KG_AFR_AF,TSPEAR
501419,21:45925635:T>C,NM_144991.2:c.1755-871A>G,\N,\N,10/11,Unknown significance,\N,intron_variant,0.652,\N,\N,TSPEAR
501420,21:45925648:A>T,NM_144991.2:c.1755-884T>A,\N,\N,10/11,Unknown significance,\N,intron_variant,1.2,\N,\N,TSPEAR
501421,21:45925672:CGTT>C,NM_144991.2:c.1755-911_1755-909del,\N,\N,10/11,Unknown significance,\N,intron_variant,6.018,\N,\N,TSPEAR
501422,21:45925675:T>C,NM_144991.2:c.1755-911A>G,\N,\N,10/11,Unknown significance,\N,intron_variant,1.407,\N,\N,TSPEAR
501423,21:45925690:G>A,NM_144991.2:c.1755-926C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,0.246,0.001,1KG_SAS_AF,TSPEAR
501424,21:45925718:A>C,NM_144991.2:c.1755-954T>G,\N,\N,10/11,Unknown significance,\N,intron_variant,0.747,\N,\N,TSPEAR
501425,21:45925751:C>T,NM_144991.2:c.1755-987G>A,\N,\N,10/11,Benign,\N,intron_variant,3.142,0.0069,1KG_EAS_AF,TSPEAR
501426,21:45925844:C>T,NM_144991.2:c.1755-1080G>A,\N,\N,10/11,Benign,\N,intron_variant,5.496,0.0257,1KG_AFR_AF,TSPEAR
501427,21:45925868:G>T,NM_144991.2:c.1755-1104C>A,\N,\N,10/11,Unknown significance,\N,intron_variant,0.21,\N,\N,TSPEAR
501428,21:45925880:T>C,NM_144991.2:c.1755-1116A>G,\N,\N,10/11,Unknown significance,\N,intron_variant,0.121,0.003,1KG_EAS_AF,TSPEAR
501429,21:45925896:G>A,NM_144991.2:c.1755-1132C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,1.814,\N,\N,TSPEAR
501430,21:45925901:C>A,NM_144991.2:c.1755-1137G>T,\N,\N,10/11,Unknown significance,\N,intron_variant,5.36,\N,\N,TSPEAR
501431,21:45925924:G>A,NM_144991.2:c.1755-1160C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,2.221,0.001,1KG_SAS_AF,TSPEAR
501432,21:45925937:C>T,NM_144991.2:c.1755-1173G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,5.65,0.001,1KG_EUR_AF,TSPEAR
501433,21:45925941:C>T,NM_144991.2:c.1755-1177G>A,\N,\N,10/11,Benign,\N,intron_variant,6.324,0.0303,1KG_AFR_AF,TSPEAR
501434,21:45925977:A>AG,NM_144991.2:c.1755-1214dup,\N,\N,10/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
501435,21:45925987:C>G,NM_144991.2:c.1755-1223G>C,\N,\N,10/11,Unknown significance,\N,intron_variant,1.418,\N,\N,TSPEAR
501436,21:45926006:A>G,NM_144991.2:c.1755-1242T>C,\N,\N,10/11,Unknown significance,\N,intron_variant,0.292,\N,\N,TSPEAR
501437,21:45926053:C>G,NM_144991.2:c.1755-1289G>C,\N,\N,10/11,Unknown significance,\N,intron_variant,1.925,\N,\N,TSPEAR
501438,21:45926081:G>A,NM_144991.2:c.1755-1317C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,1.596,0.001,1KG_SAS_AF,TSPEAR
501439,21:45926106:C>T,NM_144991.2:c.1755-1342G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,5.139,\N,\N,TSPEAR
501440,21:45926107:G>A,NM_144991.2:c.1755-1343C>T,\N,\N,10/11,Benign,\N,intron_variant,0.441,0.0089,1KG_EAS_AF,TSPEAR
501441,21:45926140:T>A,NM_144991.2:c.1755-1376A>T,\N,\N,10/11,Benign,\N,intron_variant,1.557,0.152,1KG_AFR_AF,TSPEAR
501442,21:45926153:A>C,NM_144991.2:c.1755-1389T>G,\N,\N,10/11,Unknown significance,\N,intron_variant,0.551,\N,\N,TSPEAR
501443,21:45926155:G>T,NM_144991.2:c.1755-1391C>A,\N,\N,10/11,Unknown significance,\N,intron_variant,2.55,0.0008,1KG_AFR_AF,TSPEAR
501444,21:45926214:C>T,NR_103707.1:n.285+3C>T,\N,\N,1/6,Unknown significance,\N,splice_region_variant&intron_variant&non_coding_transcript_variant,0.812,0.001,1KG_EAS_AF,TSPEAR
501445,21:45926218:G>A,NR_103707.1:n.285+7G>A,\N,\N,1/6,Unknown significance,\N,splice_region_variant&intron_variant&non_coding_transcript_variant,4.964,\N,\N,TSPEAR
501446,21:45926220:C>T,NM_144991.2:c.1755-1456G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,4.428,\N,\N,TSPEAR
501447,21:45926230:C>T,NM_144991.2:c.1755-1466G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,4.415,\N,\N,TSPEAR
501448,21:45926235:G>A,NM_144991.2:c.1755-1471C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,1.908,\N,\N,TSPEAR
501449,21:45926241:C>A,NM_144991.2:c.1755-1477G>T,\N,\N,10/11,Unknown significance,\N,intron_variant,4.303,0.002,1KG_SAS_AF,TSPEAR
501450,21:45926245:C>T,NM_144991.2:c.1755-1481G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,1.387,0.0023,1KG_AFR_AF,TSPEAR
501451,21:45926249:C>G,NM_144991.2:c.1755-1485G>C,\N,\N,10/11,Unknown significance,\N,intron_variant,1.462,\N,\N,TSPEAR
501452,21:45926259:G>A,NM_144991.2:c.1755-1495C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,0.228,0.0029,1KG_AMR_AF,TSPEAR
501453,21:45926267:CTG>C,NM_144991.2:c.1755-1505_1755-1504del,\N,\N,10/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
501454,21:45926268:T>C,NM_144991.2:c.1755-1504A>G,\N,\N,10/11,Unknown significance,\N,intron_variant,1.181,0.001,1KG_EAS_AF,TSPEAR
501455,21:45926269:G>C,NM_144991.2:c.1755-1505C>G,\N,\N,10/11,Benign,\N,intron_variant,1.041,0.0129,1KG_AFR_AF,TSPEAR
501456,21:45926280:C>A,NM_144991.2:c.1755-1516G>T,\N,\N,10/11,Unknown significance,\N,intron_variant,10.1,0.0014,1KG_AMR_AF,TSPEAR
501457,21:45926281:C>G,NM_144991.2:c.1755-1517G>C,\N,\N,10/11,Unknown significance,\N,intron_variant,7.806,\N,\N,TSPEAR
501458,21:45926307:C>G,NM_144991.2:c.1755-1543G>C,\N,\N,10/11,Unknown significance,\N,intron_variant,1.375,0.001,1KG_SAS_AF,TSPEAR
501459,21:45926323:C>T,NM_144991.2:c.1755-1559G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,3.613,\N,\N,TSPEAR
501460,21:45926324:G>A,NM_144991.2:c.1755-1560C>T,\N,\N,10/11,Benign,\N,intron_variant,1.02,0.0099,1KG_EAS_AF,TSPEAR
501461,21:45926330:T>TC,NM_144991.2:c.1755-1567dup,\N,\N,10/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
501462,21:45926352:C>T,NM_144991.2:c.1755-1588G>A,\N,\N,10/11,Benign,\N,intron_variant,5.09,0.0129,1KG_AFR_AF,TSPEAR
501463,21:45926375:A>G,NM_144991.2:c.1755-1611T>C,\N,\N,10/11,Benign,\N,intron_variant,0.386,0.0091,1KG_AFR_AF,TSPEAR
501464,21:45926404:G>A,NM_144991.2:c.1755-1640C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,2.752,0.001,1KG_EAS_AF,TSPEAR
501465,21:45926463:C>T,NM_144991.2:c.1755-1699G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,8.492,\N,\N,TSPEAR
501466,21:45926473:G>A,NM_144991.2:c.1755-1709C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,7.397,0.0015,1KG_AFR_AF,TSPEAR
501467,21:45926474:G>T,NM_144991.2:c.1755-1710C>A,\N,\N,10/11,Unknown significance,\N,intron_variant,5.095,0.001,1KG_SAS_AF,TSPEAR
501468,21:45926518:G>A,NM_144991.2:c.1755-1754C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,3.031,\N,\N,TSPEAR
501469,21:45926525:T>C,NR_103707.1:n.286-5T>C,\N,\N,1/6,Unknown significance,\N,splice_region_variant&intron_variant&non_coding_transcript_variant,1.884,0.0008,1KG_AFR_AF,TSPEAR
501470,21:45926529:G>GC,NR_103707.1:n.288dup,\N,\N,\N,Unknown significance,\N,splice_region_variant&non_coding_transcript_variant,\N,\N,\N,TSPEAR
501471,21:45926532:C>T,NR_103707.1:n.288C>T,\N,2/7,\N,Benign,\N,splice_region_variant&non_coding_transcript_exon_variant,2.296,0.0189,1KG_AFR_AF,TSPEAR
501472,21:45926533:G>A,NM_144991.2:c.1755-1769C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,2.566,0.0015,1KG_AFR_AF,TSPEAR
501473,21:45926537:C>T,NM_144991.2:c.1755-1773G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,2.83,0.001,1KG_EAS_AF,TSPEAR
501474,21:45926543:G>A,NM_144991.2:c.1755-1779C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,0.732,\N,\N,TSPEAR
501475,21:45926550:G>GGAGGAC,NM_144991.2:c.1755-1792_1755-1787dup,\N,\N,10/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
501476,21:45926560:G>A,NM_144991.2:c.1755-1796C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,3.427,0.0008,1KG_AFR_AF,TSPEAR
501477,21:45926562:C>T,NM_144991.2:c.1755-1798G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,0.234,0.0015,1KG_AFR_AF,TSPEAR
501478,21:45926563:G>A,NM_144991.2:c.1755-1799C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,1.496,0.001,1KG_EUR_AF,TSPEAR
501479,21:45926594:C>T,NM_144991.2:c.1755-1830G>A,\N,\N,10/11,Benign,\N,intron_variant,4.006,0.0069,1KG_EAS_AF,TSPEAR
501480,21:45926599:G>A,NM_144991.2:c.1755-1835C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,2.768,0.0023,1KG_AFR_AF,TSPEAR
501481,21:45926600:C>A,NM_144991.2:c.1755-1836G>T,\N,\N,10/11,Unknown significance,\N,intron_variant,6.299,0.0023,1KG_AFR_AF,TSPEAR
501482,21:45926607:C>T,NM_144991.2:c.1755-1843G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,4.296,0.002,1KG_SAS_AF,TSPEAR
501483,21:45926623:C>T,NM_144991.2:c.1755-1859G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,5.722,0.001,1KG_EUR_AF,TSPEAR
501484,21:45926624:G>A,NM_144991.2:c.1755-1860C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,1.898,0.0008,1KG_AFR_AF,TSPEAR
501485,21:45926625:C>T,NM_144991.2:c.1755-1861G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,2.279,\N,\N,TSPEAR
501486,21:45926626:G>A,NM_144991.2:c.1755-1862C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,3.065,0.001,1KG_EAS_AF,TSPEAR
501487,21:45926642:C>A,NM_144991.2:c.1755-1878G>T,\N,\N,10/11,Unknown significance,\N,intron_variant,4.46,\N,\N,TSPEAR
501488,21:45926642:C>T,NM_144991.2:c.1755-1878G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,4.168,\N,\N,TSPEAR
501489,21:45926643:G>A,NM_144991.2:c.1755-1879C>T,\N,\N,10/11,Benign,\N,intron_variant,4.86,0.0234,1KG_AFR_AF,TSPEAR
501490,21:45926668:C>T,NM_144991.2:c.1755-1904G>A,\N,\N,10/11,Benign,\N,intron_variant,3.784,0.0242,1KG_AFR_AF,TSPEAR
501491,21:45926669:G>A,NM_144991.2:c.1755-1905C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,2.323,0.0038,1KG_AFR_AF,TSPEAR
501492,21:45926675:G>C,NM_144991.2:c.1755-1911C>G,\N,\N,10/11,Unknown significance,\N,intron_variant,1.584,\N,\N,TSPEAR
501493,21:45926677:C>T,NM_144991.2:c.1755-1913G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,6.266,\N,\N,TSPEAR
501494,21:45926681:C>T,NM_144991.2:c.1755-1917G>A,\N,\N,10/11,Benign,\N,intron_variant,4.484,0.0061,1KG_AFR_AF,TSPEAR
501495,21:45926688:G>A,NM_144991.2:c.1755-1924C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,1.351,0.001,1KG_SAS_AF,TSPEAR
501496,21:45926698:C>T,NM_144991.2:c.1755-1934G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,0.728,\N,\N,TSPEAR
501497,21:45926720:G>A,NM_144991.2:c.1755-1956C>T,\N,\N,10/11,Benign,\N,intron_variant,3.419,0.0164,1KG_SAS_AF,TSPEAR
501498,21:45926733:C>G,NM_144991.2:c.1755-1969G>C,\N,\N,10/11,Unknown significance,\N,intron_variant,4.465,0.001,1KG_EAS_AF,TSPEAR
501499,21:45926736:A>G,NM_144991.2:c.1755-1972T>C,\N,\N,10/11,Unknown significance,\N,intron_variant,0.62,\N,\N,TSPEAR
501500,21:45926740:C>T,NM_144991.2:c.1755-1976G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,5.42,0.0043,1KG_AMR_AF,TSPEAR
501501,21:45926754:G>C,NM_144991.2:c.1755-1990C>G,\N,\N,10/11,Unknown significance,\N,intron_variant,3.618,0.001,1KG_EUR_AF,TSPEAR
501502,21:45926773:G>A,NM_144991.2:c.1755-2009C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,0.69,0.0008,1KG_AFR_AF,TSPEAR
501503,21:45926819:C>G,NM_144991.2:c.1755-2055G>C,\N,\N,10/11,Unknown significance,\N,intron_variant,0.285,0.003,1KG_EUR_AF,TSPEAR
501504,21:45926819:C>T,NM_144991.2:c.1755-2055G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,0.945,0.0015,1KG_AFR_AF,TSPEAR
501505,21:45926851:C>T,NM_144991.2:c.1755-2087G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,4.488,\N,\N,TSPEAR
501506,21:45926855:C>T,NM_144991.2:c.1755-2091G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,2.718,0.001,1KG_EAS_AF,TSPEAR
501507,21:45926875:C>T,NM_144991.2:c.1755-2111G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,4.196,0.001,1KG_SAS_AF,TSPEAR
501508,21:45926887:C>T,NM_144991.2:c.1755-2123G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,5.543,\N,\N,TSPEAR
501509,21:45926891:T>C,NM_144991.2:c.1755-2127A>G,\N,\N,10/11,Unknown significance,\N,intron_variant,1.037,0.001,1KG_EUR_AF,TSPEAR
501510,21:45926895:G>C,NM_144991.2:c.1755-2131C>G,\N,\N,10/11,Unknown significance,\N,intron_variant,0.4,0.0015,1KG_AFR_AF,TSPEAR
501511,21:45926897:G>A,NM_144991.2:c.1755-2133C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,3.363,0.001,1KG_EAS_AF,TSPEAR
501512,21:45926919:G>T,NM_144991.2:c.1755-2155C>A,\N,\N,10/11,Unknown significance,\N,intron_variant,1.438,0.0008,1KG_AFR_AF,TSPEAR
501513,21:45926933:C>T,NM_144991.2:c.1754+2149G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,7.656,0.001,1KG_EUR_AF,TSPEAR
501514,21:45926935:C>T,NM_144991.2:c.1754+2147G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,4.115,0.001,1KG_SAS_AF,TSPEAR
501515,21:45926952:C>T,NM_144991.2:c.1754+2130G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,6.922,0.001,1KG_EAS_AF,TSPEAR
501516,21:45926961:C>T,NM_144991.2:c.1754+2121G>A,\N,\N,10/11,Benign,\N,intron_variant,5.232,0.0072,1KG_AMR_AF,TSPEAR
501517,21:45927003:C>T,NM_144991.2:c.1754+2079G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,6.105,\N,\N,TSPEAR
501518,21:45927004:G>A,NM_144991.2:c.1754+2078C>T,\N,\N,10/11,Benign,\N,intron_variant,0.788,0.0051,1KG_SAS_AF,TSPEAR
501519,21:45927013:T>G,NM_144991.2:c.1754+2069A>C,\N,\N,10/11,Unknown significance,\N,intron_variant,2.066,0.001,1KG_EAS_AF,TSPEAR
501520,21:45927026:C>T,NM_144991.2:c.1754+2056G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,4.192,0.001,1KG_EAS_AF,TSPEAR
501521,21:45927031:C>T,NM_144991.2:c.1754+2051G>A,\N,\N,10/11,Benign,\N,intron_variant,1.573,0.0159,1KG_AFR_AF,TSPEAR
501522,21:45927061:G>A,NM_144991.2:c.1754+2021C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,5.187,\N,\N,TSPEAR
501523,21:45927061:G>C,NM_144991.2:c.1754+2021C>G,\N,\N,10/11,Unknown significance,\N,intron_variant,2.508,\N,\N,TSPEAR
501524,21:45927064:G>C,NM_144991.2:c.1754+2018C>G,\N,\N,10/11,Benign,\N,intron_variant,0.258,0.028,1KG_AFR_AF,TSPEAR
501525,21:45927065:G>T,NM_144991.2:c.1754+2017C>A,\N,\N,10/11,Unknown significance,\N,intron_variant,0.621,\N,\N,TSPEAR
501526,21:45927076:G>T,NM_144991.2:c.1754+2006C>A,\N,\N,10/11,Unknown significance,\N,intron_variant,0.919,\N,\N,TSPEAR
501527,21:45927125:G>GA,NM_144991.2:c.1754+1956dup,\N,\N,10/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
501528,21:45927145:C>T,NM_144991.2:c.1754+1937G>A,\N,\N,10/11,Benign,\N,intron_variant,1.909,0.0083,1KG_AFR_AF,TSPEAR
501529,21:45927172:T>G,NM_144991.2:c.1754+1910A>C,\N,\N,10/11,Unknown significance,\N,intron_variant,2.771,\N,\N,TSPEAR
501530,21:45927190:C>A,NM_144991.2:c.1754+1892G>T,\N,\N,10/11,Unknown significance,\N,intron_variant,1.329,\N,\N,TSPEAR
501531,21:45927190:C>T,NM_144991.2:c.1754+1892G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,0.839,\N,\N,TSPEAR
501532,21:45927208:C>T,NM_144991.2:c.1754+1874G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,0.835,\N,\N,TSPEAR
501533,21:45927241:A>C,NM_144991.2:c.1754+1841T>G,\N,\N,10/11,Unknown significance,\N,intron_variant,0.712,\N,\N,TSPEAR
501534,21:45927261:C>T,NM_144991.2:c.1754+1821G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,3.641,\N,\N,TSPEAR
501535,21:45927267:G>A,NM_144991.2:c.1754+1815C>T,\N,\N,10/11,Benign,\N,intron_variant,0.274,0.0333,1KG_AFR_AF,TSPEAR
501536,21:45927307:G>A,NM_144991.2:c.1754+1775C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,0.671,0.001,1KG_EUR_AF,TSPEAR
501537,21:45927312:C>G,NM_144991.2:c.1754+1770G>C,\N,\N,10/11,Unknown significance,\N,intron_variant,0.592,\N,\N,TSPEAR
501538,21:45927312:C>T,NM_144991.2:c.1754+1770G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,1.45,\N,\N,TSPEAR
501539,21:45927336:G>A,NM_144991.2:c.1754+1746C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,0.332,\N,\N,TSPEAR
501540,21:45927359:T>C,NM_144991.2:c.1754+1723A>G,\N,\N,10/11,Unknown significance,\N,intron_variant,2.642,\N,\N,TSPEAR
501541,21:45927387:T>TA,NM_144991.2:c.1754+1694_1754+1695insT,\N,\N,10/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
501542,21:45927391:T>G,NM_144991.2:c.1754+1691A>C,\N,\N,10/11,Benign,\N,intron_variant,7.683,0.0197,1KG_AFR_AF,TSPEAR
501543,21:45927419:ACT>A,NM_144991.2:c.1754+1661_1754+1662del,\N,\N,10/11,Benign,\N,intron_variant,2.101,0.0514,1KG_AFR_AF,TSPEAR
501544,21:45927450:C>G,NM_144991.2:c.1754+1632G>C,\N,\N,10/11,Unknown significance,\N,intron_variant,0.19,0.001,1KG_EUR_AF,TSPEAR
501545,21:45927453:T>TC,NM_144991.2:c.1754+1628dup,\N,\N,10/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
501546,21:45927482:C>T,NM_144991.2:c.1754+1600G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,1.583,0.001,1KG_SAS_AF,TSPEAR
501547,21:45927490:G>A,NM_144991.2:c.1754+1592C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,0.173,\N,\N,TSPEAR
501548,21:45927491:C>T,NM_144991.2:c.1754+1591G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,1.294,\N,\N,TSPEAR
501549,21:45927492:G>A,NM_144991.2:c.1754+1590C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,0.926,0.0045,1KG_AFR_AF,TSPEAR
501550,21:45927507:TTC>T,NM_144991.2:c.1754+1573_1754+1574del,\N,\N,10/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
501551,21:45927520:C>T,NM_144991.2:c.1754+1562G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,0.63,0.001,1KG_EAS_AF|1KG_EUR_AF,TSPEAR
501552,21:45927522:C>T,NM_144991.2:c.1754+1560G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,2.622,\N,\N,TSPEAR
501553,21:45927537:G>A,NM_144991.2:c.1754+1545C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,0.786,0.001,1KG_EAS_AF|1KG_SAS_AF,TSPEAR
501554,21:45927542:G>A,NM_144991.2:c.1754+1540C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,0.142,0.0014,1KG_AMR_AF,TSPEAR
501555,21:45927553:C>G,NM_144991.2:c.1754+1529G>C,\N,\N,10/11,Unknown significance,\N,intron_variant,2.117,\N,\N,TSPEAR
501556,21:45927599:A>G,NM_144991.2:c.1754+1483T>C,\N,\N,10/11,Unknown significance,\N,intron_variant,1.272,\N,\N,TSPEAR
501557,21:45927628:T>C,NM_144991.2:c.1754+1454A>G,\N,\N,10/11,Benign,\N,intron_variant,1.347,0.1256,1KG_AFR_AF,TSPEAR
501558,21:45927630:T>C,NM_144991.2:c.1754+1452A>G,\N,\N,10/11,Unknown significance,\N,intron_variant,1.572,0.0014,1KG_AMR_AF,TSPEAR
501559,21:45927652:T>C,NM_144991.2:c.1754+1430A>G,\N,\N,10/11,Unknown significance,\N,intron_variant,0.415,0.0038,1KG_AFR_AF,TSPEAR
501560,21:45927690:C>G,NM_144991.2:c.1754+1392G>C,\N,\N,10/11,Unknown significance,\N,intron_variant,0.988,\N,\N,TSPEAR
501561,21:45927690:C>T,NM_144991.2:c.1754+1392G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,2.084,\N,\N,TSPEAR
501562,21:45927691:G>A,NM_144991.2:c.1754+1391C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,0.021,0.0045,1KG_AFR_AF,TSPEAR
501563,21:45927707:A>G,NM_144991.2:c.1754+1375T>C,\N,\N,10/11,Unknown significance,\N,intron_variant,1.335,\N,\N,TSPEAR
501564,21:45927715:C>T,NM_144991.2:c.1754+1367G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,1.33,\N,\N,TSPEAR
501565,21:45927718:C>T,NM_144991.2:c.1754+1364G>A,\N,\N,10/11,Benign,\N,intron_variant,0.035,0.0106,1KG_AFR_AF,TSPEAR
501566,21:45927723:C>T,NM_144991.2:c.1754+1359G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,0.041,0.0008,1KG_AFR_AF,TSPEAR
501567,21:45927758:G>A,NM_144991.2:c.1754+1324C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,2.3,0.002,1KG_EUR_AF,TSPEAR
501568,21:45927760:A>G,NM_144991.2:c.1754+1322T>C,\N,\N,10/11,Unknown significance,\N,intron_variant,5.372,0.0014,1KG_AMR_AF,TSPEAR
501569,21:45927762:G>C,NM_144991.2:c.1754+1320C>G,\N,\N,10/11,Unknown significance,\N,intron_variant,1.126,0,1KG_ALL_AF|1KG_AFR_AF|1KG_AMR_AF|1KG_EAS_AF|1KG_EUR_AF|1KG_SAS_AF,TSPEAR
501570,21:45927767:A>ACGGAGCCCACAGGCAGGTCACCC,NM_144991.2:c.1754+1292_1754+1314dup,\N,\N,10/11,Benign,\N,intron_variant,0.052,0.0129,1KG_AFR_AF,TSPEAR
501571,21:45927768:C>T,NM_144991.2:c.1754+1314G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,2.063,\N,\N,TSPEAR
501572,21:45927792:G>A,NM_144991.2:c.1754+1290C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,0.242,0.001,1KG_SAS_AF,TSPEAR
501573,21:45927798:C>T,NM_144991.2:c.1754+1284G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,2.261,\N,\N,TSPEAR
501574,21:45927818:C>G,NM_144991.2:c.1754+1264G>C,\N,\N,10/11,Unknown significance,\N,intron_variant,1.064,0.002,1KG_SAS_AF,TSPEAR
501575,21:45927819:C>G,NM_144991.2:c.1754+1263G>C,\N,\N,10/11,Unknown significance,\N,intron_variant,1.483,0.001,1KG_EAS_AF,TSPEAR
501576,21:45927820:G>A,NM_144991.2:c.1754+1262C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,0.415,0.001,1KG_SAS_AF,TSPEAR
501577,21:45927823:G>A,NM_144991.2:c.1754+1259C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,0.128,0.001,1KG_EAS_AF,TSPEAR
501578,21:45927831:T>C,NM_144991.2:c.1754+1251A>G,\N,\N,10/11,Unknown significance,\N,intron_variant,0.734,0.0008,1KG_AFR_AF,TSPEAR
501579,21:45927842:T>A,NM_144991.2:c.1754+1240A>T,\N,\N,10/11,Unknown significance,\N,intron_variant,5.952,0.0008,1KG_AFR_AF,TSPEAR
501580,21:45927843:A>C,NM_144991.2:c.1754+1239T>G,\N,\N,10/11,Benign,\N,intron_variant,1.012,0.0106,1KG_AFR_AF,TSPEAR
501581,21:45927843:A>G,NM_144991.2:c.1754+1239T>C,\N,\N,10/11,Unknown significance,\N,intron_variant,1.984,\N,\N,TSPEAR
501582,21:45927873:C>A,NM_144991.2:c.1754+1209G>T,\N,\N,10/11,Unknown significance,\N,intron_variant,0.614,\N,\N,TSPEAR
501583,21:45927907:A>G,NM_144991.2:c.1754+1175T>C,\N,\N,10/11,Unknown significance,\N,intron_variant,0.285,\N,\N,TSPEAR
501584,21:45927920:C>T,NR_103707.1:n.739C>T,\N,3/7,\N,Unknown significance,\N,splice_region_variant&non_coding_transcript_exon_variant,2.369,\N,\N,TSPEAR
501585,21:45927921:C>CAGG,NR_103707.1:n.743_745dup,\N,3/7,\N,Unknown significance,\N,splice_region_variant&non_coding_transcript_exon_variant,\N,\N,\N,TSPEAR
501586,21:45927924:G>T,NM_144991.2:c.1754+1158C>A,\N,\N,10/11,Benign,\N,intron_variant,0.017,0.0219,1KG_EUR_AF,TSPEAR
501587,21:45927975:A>G,NM_144991.2:c.1754+1107T>C,\N,\N,10/11,Unknown significance,\N,intron_variant,0.843,0.001,1KG_SAS_AF,TSPEAR
501588,21:45927979:C>A,NM_144991.2:c.1754+1103G>T,\N,\N,10/11,Unknown significance,\N,intron_variant,7.781,\N,\N,TSPEAR
501589,21:45928014:C>T,NM_144991.2:c.1754+1068G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,5.887,\N,\N,TSPEAR
501590,21:45928015:G>A,NM_144991.2:c.1754+1067C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,3.578,0.001,1KG_SAS_AF,TSPEAR
501591,21:45928021:G>A,NM_144991.2:c.1754+1061C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,4.295,0.001,1KG_EUR_AF|1KG_SAS_AF,TSPEAR
501592,21:45928034:C>T,NM_144991.2:c.1754+1048G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,8.166,0.0008,1KG_AFR_AF,TSPEAR
501593,21:45928049:C>CG,NM_144991.2:c.1754+1032dup,\N,\N,10/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
501594,21:45928049:C>T,NM_144991.2:c.1754+1033G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,5.148,0.001,1KG_EAS_AF,TSPEAR
501595,21:45928055:T>C,NM_144991.2:c.1754+1027A>G,\N,\N,10/11,Benign,\N,intron_variant,2.248,0.9894,1KG_AFR_AF,TSPEAR
501596,21:45928059:C>T,NM_144991.2:c.1754+1023G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,2.036,\N,\N,TSPEAR
501597,21:45928062:G>A,NM_144991.2:c.1754+1020C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,0.706,\N,\N,TSPEAR
501598,21:45928073:C>T,NM_144991.2:c.1754+1009G>A,\N,\N,10/11,Benign,\N,intron_variant,1.343,0.028,1KG_AFR_AF,TSPEAR
501599,21:45928083:C>T,NM_144991.2:c.1754+999G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,2.703,0.0015,1KG_AFR_AF,TSPEAR
501600,21:45928093:C>T,NM_144991.2:c.1754+989G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,1.224,\N,\N,TSPEAR
501601,21:45928094:G>A,NM_144991.2:c.1754+988C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,4.482,\N,\N,TSPEAR
501602,21:45928097:C>T,NM_144991.2:c.1754+985G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,0.759,0.0031,1KG_SAS_AF,TSPEAR
501603,21:45928102:G>A,NM_144991.2:c.1754+980C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,4.686,0.001,1KG_SAS_AF,TSPEAR
501604,21:45928115:A>G,NM_144991.2:c.1754+967T>C,\N,\N,10/11,Benign,\N,intron_variant,1.813,0.0106,1KG_AFR_AF,TSPEAR
501605,21:45928161:C>T,NM_144991.2:c.1754+921G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,5.394,\N,\N,TSPEAR
501606,21:45928179:C>T,NM_144991.2:c.1754+903G>A,\N,\N,10/11,Benign,\N,intron_variant,6.456,0.0862,1KG_AFR_AF,TSPEAR
501607,21:45928180:G>A,NM_144991.2:c.1754+902C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,2.003,0.0029,1KG_AMR_AF,TSPEAR
501608,21:45928183:G>C,NM_144991.2:c.1754+899C>G,\N,\N,10/11,Unknown significance,\N,intron_variant,0.856,0.0014,1KG_AMR_AF,TSPEAR
501609,21:45928184:G>A,NM_144991.2:c.1754+898C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,1.288,\N,\N,TSPEAR
501610,21:45928194:T>C,NR_103707.1:n.1011+2T>C,\N,\N,3/6,Unknown significance,\N,splice_donor_variant&non_coding_transcript_variant,6.342,0.0014,1KG_AMR_AF,TSPEAR
501611,21:45928195:ATGTGTTGTTG>A,NR_103707.1:n.1011+9_1011+18del,\N,\N,3/6,Unknown significance,\N,splice_region_variant&intron_variant&non_coding_transcript_variant,\N,\N,\N,TSPEAR
501612,21:45928197:GTGT>G,NR_103707.1:n.1011+12_1011+14del,\N,\N,3/6,Unknown significance,\N,splice_region_variant&intron_variant&non_coding_transcript_variant,\N,\N,\N,TSPEAR
501613,21:45928224:T>C,NM_144991.2:c.1754+858A>G,\N,\N,10/11,Unknown significance,\N,intron_variant,0.74,0.0008,1KG_AFR_AF,TSPEAR
501614,21:45928262:C>T,NM_144991.2:c.1754+820G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,0.046,0.001,1KG_EAS_AF,TSPEAR
501615,21:45928271:T>C,NM_144991.2:c.1754+811A>G,\N,\N,10/11,Unknown significance,\N,intron_variant,0.626,\N,\N,TSPEAR
501616,21:45928286:C>A,NM_144991.2:c.1754+796G>T,\N,\N,10/11,Benign,\N,intron_variant,2.602,0.0106,1KG_AFR_AF,TSPEAR
501617,21:45928288:C>T,NM_144991.2:c.1754+794G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,2.727,0.002,1KG_EUR_AF,TSPEAR
501618,21:45928337:C>T,NM_144991.2:c.1754+745G>A,\N,\N,10/11,Benign,\N,intron_variant,1.957,0.028,1KG_AFR_AF,TSPEAR
501619,21:45928363:T>C,NM_144991.2:c.1754+719A>G,\N,\N,10/11,Unknown significance,\N,intron_variant,0.17,\N,\N,TSPEAR
501620,21:45928380:A>T,NM_144991.2:c.1754+702T>A,\N,\N,10/11,Benign,\N,intron_variant,2.955,0.0371,1KG_AFR_AF,TSPEAR
501621,21:45928390:T>C,NM_144991.2:c.1754+692A>G,\N,\N,10/11,Unknown significance,\N,intron_variant,1.397,0.0014,1KG_AMR_AF,TSPEAR
501622,21:45928392:C>T,NM_144991.2:c.1754+690G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,0.222,\N,\N,TSPEAR
501623,21:45928394:G>T,NM_144991.2:c.1754+688C>A,\N,\N,10/11,Unknown significance,\N,intron_variant,0.385,\N,\N,TSPEAR
501624,21:45928398:C>T,NM_144991.2:c.1754+684G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,1.057,\N,\N,TSPEAR
501625,21:45928399:G>A,NM_144991.2:c.1754+683C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,0.022,\N,\N,TSPEAR
501626,21:45928401:T>C,NM_144991.2:c.1754+681A>G,\N,\N,10/11,Unknown significance,\N,intron_variant,1.928,\N,\N,TSPEAR
501627,21:45928420:C>T,NM_144991.2:c.1754+662G>A,\N,\N,10/11,Benign,\N,intron_variant,1.029,0.0102,1KG_SAS_AF,TSPEAR
501628,21:45928421:C>T,NM_144991.2:c.1754+661G>A,\N,\N,10/11,Benign,\N,intron_variant,2.717,0.0288,1KG_EUR_AF,TSPEAR
501629,21:45928442:G>A,NM_144991.2:c.1754+640C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,4.075,0.0008,1KG_AFR_AF,TSPEAR
501630,21:45928472:C>T,NM_144991.2:c.1754+610G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,2.781,0.0008,1KG_AFR_AF,TSPEAR
501631,21:45928482:A>G,NM_144991.2:c.1754+600T>C,\N,\N,10/11,Benign,\N,intron_variant,2.775,0.0106,1KG_AFR_AF,TSPEAR
501632,21:45928493:TGTG>T,NM_144991.2:c.1754+586_1754+588del,\N,\N,10/11,Unknown significance,\N,intron_variant,5.609,\N,\N,TSPEAR
501633,21:45928504:C>T,NM_144991.2:c.1754+578G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,1.705,0.0031,1KG_SAS_AF,TSPEAR
501634,21:45928529:C>T,NM_144991.2:c.1754+553G>A,\N,\N,10/11,Benign,\N,intron_variant,0.195,0.0079,1KG_EAS_AF,TSPEAR
501635,21:45928557:G>A,NM_144991.2:c.1754+525C>T,\N,\N,10/11,Benign,\N,intron_variant,2.878,0.0106,1KG_AFR_AF,TSPEAR
501636,21:45928559:A>G,NM_144991.2:c.1754+523T>C,\N,\N,10/11,Unknown significance,\N,intron_variant,2.764,0.0023,1KG_AFR_AF,TSPEAR
501637,21:45928567:A>G,NM_144991.2:c.1754+515T>C,\N,\N,10/11,Unknown significance,\N,intron_variant,1.991,0.0008,1KG_AFR_AF,TSPEAR
501638,21:45928570:C>T,NM_144991.2:c.1754+512G>A,\N,\N,10/11,Benign,\N,intron_variant,4.592,0.0229,1KG_EUR_AF,TSPEAR
501639,21:45928574:C>G,NM_144991.2:c.1754+508G>C,\N,\N,10/11,Unknown significance,\N,intron_variant,1.949,0.0008,1KG_AFR_AF,TSPEAR
501640,21:45928578:A>G,NM_144991.2:c.1754+504T>C,\N,\N,10/11,Benign,\N,intron_variant,0.195,0.0106,1KG_AFR_AF,TSPEAR
501641,21:45928579:T>C,NM_144991.2:c.1754+503A>G,\N,\N,10/11,Unknown significance,\N,intron_variant,0.966,\N,\N,TSPEAR
501642,21:45928588:G>C,NM_144991.2:c.1754+494C>G,\N,\N,10/11,Unknown significance,\N,intron_variant,0.926,0.0015,1KG_AFR_AF,TSPEAR
501643,21:45928612:C>T,NR_103707.1:n.1014C>T,\N,4/7,\N,Unknown significance,\N,splice_region_variant&non_coding_transcript_exon_variant,1.796,\N,\N,TSPEAR
501644,21:45928616:C>T,NM_144991.2:c.1754+466G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,6.051,0.003,1KG_EAS_AF,TSPEAR
501645,21:45928619:C>T,NM_144991.2:c.1754+463G>A,\N,\N,10/11,Benign,\N,intron_variant,0.014,0.0143,1KG_SAS_AF,TSPEAR
501646,21:45928625:C>T,NM_144991.2:c.1754+457G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,7.107,0.003,1KG_AFR_AF,TSPEAR
501647,21:45928632:T>G,NM_144991.2:c.1754+450A>C,\N,\N,10/11,Unknown significance,\N,intron_variant,0.461,\N,\N,TSPEAR
501648,21:45928640:G>A,NM_144991.2:c.1754+442C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,2.188,\N,\N,TSPEAR
501649,21:45928648:T>A,NM_144991.2:c.1754+434A>T,\N,\N,10/11,Unknown significance,\N,intron_variant,2.993,0.001,1KG_SAS_AF,TSPEAR
501650,21:45928653:C>T,NM_144991.2:c.1754+429G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,6.508,\N,\N,TSPEAR
501651,21:45928657:G>A,NM_144991.2:c.1754+425C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,1.928,\N,\N,TSPEAR
501652,21:45928666:A>G,NM_144991.2:c.1754+416T>C,\N,\N,10/11,Benign,\N,intron_variant,1.638,0.0106,1KG_AFR_AF,TSPEAR
501653,21:45928705:C>T,NM_144991.2:c.1754+377G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,4.564,0.00025974,EXAC_EAS_AF,TSPEAR
501654,21:45928706:G>T,NM_144991.2:c.1754+376C>A,\N,\N,10/11,Unknown significance,\N,intron_variant,1.756,0.000257599,EXAC_EAS_AF,TSPEAR
501655,21:45928711:C>G,NM_144991.2:c.1754+371G>C,\N,\N,10/11,Unknown significance,\N,intron_variant,3.963,0.00025113,EXAC_EAS_AF,TSPEAR
501656,21:45928713:C>T,NM_144991.2:c.1754+369G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,4.986,0.0000622316,EXAC_NFE_AF,TSPEAR
501657,21:45928714:G>A,NM_144991.2:c.1754+368C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,2.892,0.0008,1KG_AFR_AF,TSPEAR
501658,21:45928721:G>A,NM_144991.2:c.1754+361C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,4.691,0.000462535,EXAC_FIN_AF,TSPEAR
501659,21:45928724:C>T,NM_144991.2:c.1754+358G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,4.782,\N,\N,TSPEAR
501660,21:45928727:C>T,NM_144991.2:c.1754+355G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,5.283,0.00009522,EXAC_SAS_AF,TSPEAR
501661,21:45928728:G>A,NM_144991.2:c.1754+354C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,0.068,0.000932401,EXAC_EAS_AF,TSPEAR
501662,21:45928730:A>G,NM_144991.2:c.1754+352T>C,\N,\N,10/11,Unknown significance,\N,intron_variant,1.156,0.000437063,EXAC_FIN_AF,TSPEAR
501663,21:45928736:C>T,NM_144991.2:c.1754+346G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,6.856,\N,\N,TSPEAR
501664,21:45928737:C>G,NM_144991.2:c.1754+345G>C,\N,\N,10/11,Unknown significance,\N,intron_variant,4.548,0.00326141,EXAC_AFR_AF,TSPEAR
501665,21:45928742:G>T,NM_144991.2:c.1754+340C>A,\N,\N,10/11,Unknown significance,\N,intron_variant,2.507,0.000168919,EXAC_AMR_AF,TSPEAR
501666,21:45928749:C>T,NM_144991.2:c.1754+333G>A,\N,\N,10/11,Benign,\N,intron_variant,0.01,0.114725,EXAC_AFR_AF,TSPEAR
501667,21:45928750:G>A,NM_144991.2:c.1754+332C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,2.968,0.000323625,EXAC_AMR_AF,TSPEAR
501668,21:45928751:G>C,NM_144991.2:c.1754+331C>G,\N,\N,10/11,Unknown significance,\N,intron_variant,0.564,0.000483559,EXAC_AMR_AF,TSPEAR
501669,21:45928752:C>T,NM_144991.2:c.1754+330G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,4.905,0.000571429,EVS_AA_AF,TSPEAR
501670,21:45928755:T>A,NM_144991.2:c.1754+327A>T,\N,\N,10/11,Unknown significance,\N,intron_variant,1.915,0.000158529,EXAC_AMR_AF,TSPEAR
501671,21:45928756:C>T,NM_144991.2:c.1754+326G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,4.715,0.000158629,EXAC_AMR_AF,TSPEAR
501672,21:45928757:C>T,NM_144991.2:c.1754+325G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,2.839,0.0008,1KG_AFR_AF,TSPEAR
501673,21:45928759:T>A,NM_144991.2:c.1754+323A>T,\N,\N,10/11,Unknown significance,\N,intron_variant,5.1,0.000026111,EXAC_NFE_AF,TSPEAR
501674,21:45928761:C>T,NM_144991.2:c.1754+321G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,4.635,0.0014,1KG_AMR_AF,TSPEAR
501675,21:45928762:G>A,NM_144991.2:c.1754+320C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,1.251,0.0000261178,EXAC_NFE_AF,TSPEAR
501676,21:45928762:G>C,NM_144991.2:c.1754+320C>G,\N,\N,10/11,Unknown significance,\N,intron_variant,0.384,0.000272826,EXAC_SAS_AF,TSPEAR
501677,21:45928765:C>T,NM_144991.2:c.1754+317G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,0.88,0.00015674,EXAC_AMR_AF,TSPEAR
501678,21:45928766:G>A,NM_144991.2:c.1754+316C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,0.379,0.00156986,EXAC_AMR_AF,TSPEAR
501679,21:45928768:C>T,NM_144991.2:c.1754+314G>A,\N,\N,10/11,Benign,\N,intron_variant,5.315,0.00954283,EXAC_AFR_AF,TSPEAR
501680,21:45928769:G>A,NM_144991.2:c.1754+313C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,3.041,0.00118289,EXAC_SAS_AF,TSPEAR
501681,21:45928781:C>T,NM_144991.2:c.1754+301G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,6.6,0.0043,1KG_AMR_AF,TSPEAR
501682,21:45928782:C>T,NM_144991.2:c.1754+300G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,6.748,0.0000271047,EXAC_NFE_AF,TSPEAR
501683,21:45928790:C>T,NM_144991.2:c.1754+292G>A,\N,\N,10/11,Benign,\N,intron_variant,6.759,0.0231023,EXAC_AFR_AF,TSPEAR
501684,21:45928794:A>G,NM_144991.2:c.1754+288T>C,\N,\N,10/11,Unknown significance,\N,intron_variant,3.066,0.000365764,EXAC_FIN_AF,TSPEAR
501685,21:45928800:C>T,NM_144991.2:c.1754+282G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,4.814,0.000373692,EXAC_AMR_AF,TSPEAR
501686,21:45928801:G>A,NM_144991.2:c.1754+281C>T,\N,\N,10/11,Benign,\N,intron_variant,0.768,0.00644567,EXAC_EAS_AF,TSPEAR
501687,21:45928809:G>A,NM_144991.2:c.1754+273C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,2.038,0.0000298205,EXAC_NFE_AF,TSPEAR
501688,21:45928812:G>A,NR_103707.1:n.1214G>A,\N,4/7,\N,Unknown significance,\N,splice_region_variant&non_coding_transcript_exon_variant,0.478,0.0014,1KG_AMR_AF,TSPEAR
501689,21:45928812:G>GGT,NR_103707.1:n.1214+1_1214+2dup,\N,\N,\N,Unknown significance,\N,splice_region_variant&non_coding_transcript_variant,2.748,0.0000973141,EXAC_SAS_AF,TSPEAR
501690,21:45928827:G>A,NM_144991.2:c.1754+255C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,0.455,\N,\N,TSPEAR
501691,21:45928833:G>A,NM_144991.2:c.1754+249C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,0.404,0,EXAC_ALL_AF|EXAC_AFR_AF|EXAC_AMR_AF|EXAC_EAS_AF|EXAC_FIN_AF|EXAC_NFE_AF|EXAC_OTH_AF|EXAC_SAS_AF,TSPEAR
501692,21:45928833:G>GA,NM_144991.2:c.1754+248dup,\N,\N,10/11,Unknown significance,\N,intron_variant,1.351,0.000309406,EXAC_EAS_AF,TSPEAR
501693,21:45928839:C>T,NM_144991.2:c.1754+243G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,2.342,0.0023,1KG_AFR_AF,TSPEAR
501694,21:45928853:G>A,NM_144991.2:c.1754+229C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,6.211,\N,\N,TSPEAR
501695,21:45928883:C>A,NM_144991.2:c.1754+199G>T,\N,\N,10/11,Unknown significance,\N,intron_variant,5.358,\N,\N,TSPEAR
501696,21:45928883:C>T,NM_144991.2:c.1754+199G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,5.442,\N,\N,TSPEAR
501697,21:45928884:G>A,NM_144991.2:c.1754+198C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,1.275,0.001,1KG_EAS_AF,TSPEAR
501698,21:45928891:A>G,NM_144991.2:c.1754+191T>C,\N,\N,10/11,Unknown significance,\N,intron_variant,0.843,0.0023,1KG_AFR_AF,TSPEAR
501699,21:45928893:TTCCCCAGGCCAGGAAAG>T,NM_144991.2:c.1754+172_1754+188del,\N,\N,10/11,Unknown significance,\N,intron_variant,3.474,\N,\N,TSPEAR
501700,21:45928893:TTCCCCAGGCCAGGAAAGTCCCCAGGCCATTCTTTCCACAGGAAGG>T,NM_144991.2:c.1754+144_1754+188del,\N,\N,10/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
501701,21:45928907:A>G,NM_144991.2:c.1754+175T>C,\N,\N,10/11,Unknown significance,\N,intron_variant,3.564,0.0008,1KG_AFR_AF,TSPEAR
501702,21:45928909:A>G,NM_144991.2:c.1754+173T>C,\N,\N,10/11,Unknown significance,\N,intron_variant,1.686,0.0008,1KG_AFR_AF,TSPEAR
501703,21:45928920:C>T,NM_144991.2:c.1754+162G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,7.069,\N,\N,TSPEAR
501704,21:45928923:T>C,NM_144991.2:c.1754+159A>G,\N,\N,10/11,Unknown significance,\N,intron_variant,4.909,\N,\N,TSPEAR
501705,21:45928950:T>G,NM_144991.2:c.1754+132A>C,\N,\N,10/11,Unknown significance,\N,intron_variant,1.886,\N,\N,TSPEAR
501706,21:45928960:A>G,NM_144991.2:c.1754+122T>C,\N,\N,10/11,Unknown significance,\N,intron_variant,0.58,\N,\N,TSPEAR
501707,21:45928988:G>A,NM_144991.2:c.1754+94C>T,\N,\N,10/11,Unknown significance,\N,intron_variant,0.254,0.0008,1KG_AFR_AF,TSPEAR
501708,21:45929023:C>T,NM_144991.2:c.1754+59G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,0.214,0.001,1KG_EAS_AF,TSPEAR
501709,21:45929024:G>A,NM_144991.2:c.1754+58C>T,\N,\N,10/11,Benign,\N,intron_variant,1.662,0.0151,1KG_AFR_AF,TSPEAR
501710,21:45929036:C>T,NM_144991.2:c.1754+46G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,1.368,0.0000162038,EXAC_NFE_AF,TSPEAR
501711,21:45929045:A>C,NM_144991.2:c.1754+37T>G,\N,\N,10/11,Benign,\N,intron_variant,0.064,0.0140717,EVS_AA_AF,TSPEAR
501712,21:45929045:A>G,NM_144991.2:c.1754+37T>C,\N,\N,10/11,Unknown significance,\N,intron_variant,0.224,0.000093214,EXAC_AMR_AF,TSPEAR
501713,21:45929048:A>G,NM_144991.2:c.1754+34T>C,\N,\N,10/11,Unknown significance,\N,intron_variant,2.649,0.000016071,EXAC_NFE_AF,TSPEAR
501714,21:45929055:C>T,NM_144991.2:c.1754+27G>A,\N,\N,10/11,Unknown significance,\N,intron_variant,1.897,\N,\N,TSPEAR
501715,21:45929062:T>C,NM_144991.2:c.1754+20A>G,\N,\N,10/11,Unknown significance,\N,intron_variant,2.492,0.0000157535,EXAC_NFE_AF,TSPEAR
501716,21:45929068:G>GT,NM_144991.2:c.1754+13dup,\N,\N,10/11,Unknown significance,\N,intron_variant,1.777,\N,\N,TSPEAR
501717,21:45929075:C>T,NM_144991.2:c.1754+7G>A,\N,\N,10/11,Unknown significance,\N,splice_region_variant&intron_variant,3.544,0.002,1KG_EAS_AF,TSPEAR
501718,21:45929076:G>A,NM_144991.2:c.1754+6C>T,\N,\N,10/11,Unknown significance,\N,splice_region_variant&intron_variant,0.515,0.000234412,EXAC_EAS_AF,TSPEAR
501719,21:45929078:A>G,NM_144991.2:c.1754+4T>C,\N,\N,10/11,Unknown significance,\N,splice_region_variant&intron_variant,2.135,0.0000307654,EXAC_NFE_AF,TSPEAR
501720,21:45929079:T>C,NM_144991.2:c.1754+3A>G,\N,\N,10/11,Unknown significance,\N,splice_region_variant&intron_variant,2.505,\N,\N,TSPEAR
501721,21:45929081:C>T,NM_144991.2:c.1754+1G>A,\N,\N,10/11,Unknown significance,\N,splice_donor_variant,23.9,0.000389358,EXAC_SAS_AF,TSPEAR
501722,21:45929082:C>A,NM_144991.2:c.1754G>T,NP_659428.2:p.Ser585Ile,10/12,\N,Unknown significance,\N,missense_variant&splice_region_variant,29.3,0.0000919991,EXAC_NFE_AF,TSPEAR
501723,21:45929086:A>G,NM_144991.2:c.1750T>C,NP_659428.2:p.Cys584Arg,10/12,\N,Unknown significance,\N,missense_variant,22.3,\N,\N,TSPEAR
501724,21:45929090:G>A,NM_144991.2:c.1746C>T,NP_659428.2:p.Leu582=,10/12,\N,Benign,\N,synonymous_variant,6.663,0.0173383,EXAC_FIN_AF,TSPEAR
501725,21:45929091:A>G,NM_144991.2:c.1745T>C,NP_659428.2:p.Leu582Pro,10/12,\N,Likely benign,\N,missense_variant,8.629,0.0000152304,EXAC_NFE_AF,TSPEAR
501726,21:45929097:T>C,NM_144991.2:c.1739A>G,NP_659428.2:p.Asp580Gly,10/12,\N,Unknown significance,\N,missense_variant,24,0.000115821,EXAC_EAS_AF,TSPEAR
501727,21:45929105:C>G,NM_144991.2:c.1731G>C,NP_659428.2:p.Lys577Asn,10/12,\N,Unknown significance,\N,missense_variant,26,0.0000618659,EXAC_SAS_AF,TSPEAR
501728,21:45929107:TG>T,NM_144991.2:c.1728del,NP_659428.2:p.Lys577SerfsTer37,10/12,\N,Unknown significance,\N,frameshift_variant,35,0.0000871688,EXAC_AMR_AF,TSPEAR
501729,21:45929108:GAC>AA,NM_144991.2:c.1726_1728delinsTT,NP_659428.2:p.Val576LeufsTer38,10/12,\N,Pathogenic,Sensorineural deafness,frameshift_variant,\N,\N,\N,TSPEAR
501730,21:45929110:C>T,NM_144991.2:c.1726G>A,NP_659428.2:p.Val576Ile,10/12,\N,Likely benign,\N,missense_variant,23.4,0.0000151236,EXAC_NFE_AF,TSPEAR
501731,21:45929110:CAA>C,NM_144991.2:c.1724_1725del,NP_659428.2:p.Phe575CysfsTer118,10/12,\N,Unknown significance,\N,frameshift_variant,35,0.0000302471,EXAC_NFE_AF,TSPEAR
501732,21:45929110:C>A,NM_144991.2:c.1726G>T,NP_659428.2:p.Val576Phe,10/12,\N,Unknown significance,\N,missense_variant,24.2,0.0000870777,EXAC_AMR_AF,TSPEAR
501733,21:45929119:G>A,NM_144991.2:c.1717C>T,NP_659428.2:p.Gln573Ter,10/12,\N,Unknown significance,\N,stop_gained,37,\N,\N,TSPEAR
501734,21:45929120:C>T,NM_144991.2:c.1716G>A,NP_659428.2:p.Ala572=,10/12,\N,Unknown significance,\N,synonymous_variant,15.68,0.0000869565,EXAC_AMR_AF,TSPEAR
501735,21:45929121:G>A,NM_144991.2:c.1715C>T,NP_659428.2:p.Ala572Val,10/12,\N,Unknown significance,\N,missense_variant,22.6,0.000115768,EXAC_EAS_AF,TSPEAR
501736,21:45929121:GCGGTC>G,NM_144991.2:c.1710_1714del,NP_659428.2:p.Thr571AlafsTer121,10/12,\N,Unknown significance,\N,frameshift_variant,35,0.0000603482,EXAC_NFE_AF,TSPEAR
501737,21:45929122:C>G,NM_144991.2:c.1714G>C,NP_659428.2:p.Ala572Pro,10/12,\N,Likely benign,\N,missense_variant,24.9,0.0000150884,EXAC_NFE_AF,TSPEAR
501738,21:45929122:C>T,NM_144991.2:c.1714G>A,NP_659428.2:p.Ala572Thr,10/12,\N,Likely benign,\N,missense_variant,21.6,0.000226963,EVS_AA_AF,TSPEAR
501739,21:45929123:G>A,NM_144991.2:c.1713C>T,NP_659428.2:p.Thr571=,10/12,\N,Unknown significance,\N,synonymous_variant,14.17,0.00048459,EXAC_AFR_AF,TSPEAR
501740,21:45929128:C>G,NM_144991.2:c.1708G>C,NP_659428.2:p.Val570Leu,10/12,\N,Likely benign,\N,missense_variant,18.25,0.00006031,EXAC_NFE_AF,TSPEAR
501741,21:45929128:C>T,NM_144991.2:c.1708G>A,NP_659428.2:p.Val570Met,10/12,\N,Likely benign,\N,missense_variant,23.2,0.000348837,EVS_EA_AF,TSPEAR
501742,21:45929134:G>C,NR_103707.1:n.1215-1G>C,\N,\N,4/6,Unknown significance,\N,splice_acceptor_variant&non_coding_transcript_variant,26.3,0.001,1KG_EAS_AF,TSPEAR
501743,21:45929137:C>T,NM_144991.2:c.1699G>A,NP_659428.2:p.Glu567Lys,10/12,\N,Unknown significance,\N,missense_variant,24.3,0.0000609682,EXAC_SAS_AF,TSPEAR
501744,21:45929138:G>A,NM_144991.2:c.1698C>T,NP_659428.2:p.Tyr566=,10/12,\N,Unknown significance,\N,synonymous_variant,15.17,0.000607533,EXAC_AMR_AF,TSPEAR
501745,21:45929139:T>C,NM_144991.2:c.1697A>G,NP_659428.2:p.Tyr566Cys,10/12,\N,Unknown significance,\N,missense_variant,26.1,0.0000301314,EXAC_NFE_AF,TSPEAR
501746,21:45929141:G>A,NM_144991.2:c.1695C>T,NP_659428.2:p.Ile565=,10/12,\N,Unknown significance,\N,synonymous_variant,14.1,0.0000966557,EXAC_AFR_AF,TSPEAR
501747,21:45929145:A>T,NM_144991.2:c.1691T>A,NP_659428.2:p.Val564Asp,10/12,\N,Unknown significance,\N,missense_variant,23.3,0.001,1KG_EAS_AF,TSPEAR
501748,21:45929146:C>T,NM_144991.2:c.1690G>A,NP_659428.2:p.Val564Ile,10/12,\N,Likely benign,\N,missense_variant,21.5,0.001,1KG_SAS_AF,TSPEAR
501749,21:45929147:G>A,NM_144991.2:c.1689C>T,NP_659428.2:p.Ser563=,10/12,\N,Unknown significance,\N,synonymous_variant,1.42,0.000462856,EXAC_EAS_AF,TSPEAR
501750,21:45929149:A>G,NM_144991.2:c.1687T>C,NP_659428.2:p.Ser563Pro,10/12,\N,Unknown significance,\N,missense_variant,25.9,0.000030125,EXAC_NFE_AF,TSPEAR
501751,21:45929150:G>A,NM_144991.2:c.1686C>T,NP_659428.2:p.Asn562=,10/12,\N,Unknown significance,\N,synonymous_variant,8.254,0.0000868056,EXAC_AMR_AF,TSPEAR
501752,21:45929158:CAT>C,NM_144991.2:c.1676_1677del,NP_659428.2:p.Tyr559CysfsTer134,10/12,\N,Pathogenic,Non-syndromic deafness| autosomal recessive| DFNB98,frameshift_variant,34,0.000120533,EXAC_NFE_AF,TSPEAR
501753,21:45929159:A>G,NM_144991.2:c.1677T>C,NP_659428.2:p.Tyr559=,10/12,\N,Unknown significance,\N,synonymous_variant,2.564,0.0000150693,EXAC_NFE_AF,TSPEAR
501754,21:45929160:T>C,NM_144991.2:c.1676A>G,NP_659428.2:p.Tyr559Cys,10/12,\N,Unknown significance,\N,missense_variant,24.5,0.000120562,EXAC_NFE_AF,TSPEAR
501755,21:45929161:A>G,NM_144991.2:c.1675T>C,NP_659428.2:p.Tyr559His,10/12,\N,Unknown significance,\N,missense_variant,24.1,0.0000150711,EXAC_NFE_AF,TSPEAR
501756,21:45929162:G>A,NM_144991.2:c.1674C>T,NP_659428.2:p.Ser558=,10/12,\N,Unknown significance,\N,synonymous_variant,8.182,0.00042605,EXAC_SAS_AF,TSPEAR
501757,21:45929168:A>G,NM_144991.2:c.1668T>C,NP_659428.2:p.Asn556=,10/12,\N,Unknown significance,\N,synonymous_variant,3.38,0.000226963,EVS_AA_AF,TSPEAR
501758,21:45929181:A>C,NM_144991.2:c.1655T>G,NP_659428.2:p.Met552Arg,10/12,\N,Likely benign,\N,missense_variant,4.235,0.001,1KG_EUR_AF,TSPEAR
501759,21:45929189:A>G,NM_144991.2:c.1647T>C,NP_659428.2:p.Asp549=,10/12,\N,Unknown significance,\N,synonymous_variant,3.639,0.000152672,EXAC_FIN_AF,TSPEAR
501760,21:45929191:C>T,NM_144991.2:c.1645G>A,NP_659428.2:p.Asp549Asn,10/12,\N,Unknown significance,\N,missense_variant,24,0.000291829,EXAC_AFR_AF,TSPEAR
501761,21:45929192:G>A,NM_144991.2:c.1644C>T,NP_659428.2:p.Tyr548=,10/12,\N,Benign,\N,synonymous_variant,8.825,0.0313209,EVS_AA_AF,TSPEAR
501762,21:45929193:T>C,NM_144991.2:c.1643A>G,NP_659428.2:p.Tyr548Cys,10/12,\N,Unknown significance,\N,missense_variant,23.9,0.0000151176,EXAC_NFE_AF,TSPEAR
501763,21:45929196:C>T,NM_144991.2:c.1640G>A,NP_659428.2:p.Ser547Asn,10/12,\N,Likely benign,\N,missense_variant,10.77,0.000061282,EXAC_SAS_AF,TSPEAR
501764,21:45929204:G>A,NM_144991.2:c.1632C>T,NP_659428.2:p.Asn544=,10/12,\N,Unknown significance,\N,synonymous_variant,2.193,0.000232558,EVS_EA_AF,TSPEAR
501765,21:45929209:C>T,NM_144991.2:c.1627G>A,NP_659428.2:p.Ala543Thr,10/12,\N,Unknown significance,\N,missense_variant,26.6,\N,\N,TSPEAR
501766,21:45929215:C>T,NM_144991.2:c.1621G>A,NP_659428.2:p.Ala541Thr,10/12,\N,Unknown significance,\N,missense_variant,28,0.0000304544,EXAC_NFE_AF,TSPEAR
501767,21:45929219:G>A,NM_144991.2:c.1617C>T,NP_659428.2:p.Phe539=,10/12,\N,Unknown significance,\N,synonymous_variant,12.35,0.000116279,EVS_EA_AF,TSPEAR
501768,21:45929231:C>A,NM_144991.2:c.1605G>T,NP_659428.2:p.Gly535=,10/12,\N,Unknown significance,\N,synonymous_variant,17.84,0.0000153709,EXAC_NFE_AF,TSPEAR
501769,21:45929233:C>G,NM_144991.2:c.1603G>C,NP_659428.2:p.Gly535Arg,10/12,\N,Unknown significance,\N,missense_variant,23.4,0.000101174,EXAC_AFR_AF,TSPEAR
501770,21:45929233:C>T,NM_144991.2:c.1603G>A,NP_659428.2:p.Gly535Arg,10/12,\N,Unknown significance,\N,missense_variant,23.7,0.00018757,EXAC_SAS_AF,TSPEAR
501771,21:45929234:G>A,NM_144991.2:c.1602C>T,NP_659428.2:p.Ile534=,10/12,\N,Unknown significance,\N,synonymous_variant,13.04,0.0008,1KG_AFR_AF,TSPEAR
501772,21:45929235:A>G,NM_144991.2:c.1601T>C,NP_659428.2:p.Ile534Thr,10/12,\N,Unknown significance,\N,missense_variant,26.8,0.000101256,EXAC_AFR_AF,TSPEAR
501773,21:45929237:C>T,NM_144991.2:c.1599G>A,NP_659428.2:p.Gln533=,10/12,\N,Unknown significance,\N,synonymous_variant,14.23,0.000116279,EVS_EA_AF,TSPEAR
501774,21:45929250:C>T,NM_144991.2:c.1586G>A,NP_659428.2:p.Trp529Ter,10/12,\N,Unknown significance,\N,stop_gained,47,0.0008,1KG_AFR_AF,TSPEAR
501775,21:45929260:C>T,NM_144991.2:c.1576G>A,NP_659428.2:p.Ala526Thr,10/12,\N,Unknown significance,\N,missense_variant,27.9,0.001,1KG_EUR_AF,TSPEAR
501776,21:45929262:C>T,NM_144991.2:c.1574G>A,NP_659428.2:p.Gly525Asp,10/12,\N,Unknown significance,\N,missense_variant,24.4,0.000116279,EVS_EA_AF,TSPEAR
501777,21:45929263:C>G,NM_144991.2:c.1573G>C,NP_659428.2:p.Gly525Arg,10/12,\N,Unknown significance,\N,missense_variant,24.9,0.000610418,EXAC_SAS_AF,TSPEAR
501778,21:45929263:C>T,NM_144991.2:c.1573G>A,NP_659428.2:p.Gly525Ser,10/12,\N,Unknown significance,\N,missense_variant,25.1,0.001,1KG_SAS_AF,TSPEAR
501779,21:45929264:G>A,NM_144991.2:c.1572C>T,NP_659428.2:p.Phe524=,10/12,\N,Unknown significance,\N,synonymous_variant,10.31,0.0000329728,EXAC_NFE_AF,TSPEAR
501780,21:45929264:G>T,NM_144991.2:c.1572C>A,NP_659428.2:p.Phe524Leu,10/12,\N,Likely benign,\N,missense_variant,11.35,0.000116279,EVS_EA_AF,TSPEAR
501781,21:45929265:A>C,NM_144991.2:c.1571T>G,NP_659428.2:p.Phe524Cys,10/12,\N,Unknown significance,\N,missense_variant,24.3,0.000205931,EXAC_SAS_AF,TSPEAR
501782,21:45929268:G>A,NM_144991.2:c.1568C>T,NP_659428.2:p.Thr523Met,10/12,\N,Unknown significance,\N,missense_variant&splice_region_variant,28.5,0.001,1KG_EUR_AF,TSPEAR
501783,21:45929270:C>T,NM_144991.2:c.1567-1G>A,\N,\N,9/11,Unknown significance,\N,splice_acceptor_variant,24.1,0.000226963,EVS_AA_AF,TSPEAR
501784,21:45929277:C>T,NM_144991.2:c.1567-8G>A,\N,\N,9/11,Unknown significance,\N,splice_region_variant&intron_variant,9.511,0.000101235,EXAC_AMR_AF,TSPEAR
501785,21:45929280:AG>A,NM_144991.2:c.1567-12del,\N,\N,9/11,Unknown significance,\N,intron_variant,1.743,0.0000350963,EXAC_NFE_AF,TSPEAR
501786,21:45929281:G>A,NM_144991.2:c.1567-12C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,5.072,0.000116877,EXAC_AFR_AF,TSPEAR
501787,21:45929283:A>G,NM_144991.2:c.1567-14T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,6.661,0.000103756,EXAC_AMR_AF,TSPEAR
501788,21:45929286:G>A,NM_144991.2:c.1567-17C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,2.373,0.0000180766,EXAC_NFE_AF,TSPEAR
501789,21:45929288:A>AGGTGCAGAGGTGTGGGGGAGCG,NR_103707.1:n.1369+2_1369+23dup,\N,5/7,\N,Unknown significance,\N,splice_region_variant&non_coding_transcript_exon_variant,0.028,\N,\N,TSPEAR
501790,21:45929288:A>G,NR_103707.1:n.1368A>G,\N,5/7,\N,Unknown significance,\N,splice_region_variant&non_coding_transcript_exon_variant,0.233,\N,\N,TSPEAR
501791,21:45929289:G>A,NR_103707.1:n.1369G>A,\N,5/7,\N,Unknown significance,\N,splice_region_variant&non_coding_transcript_exon_variant,1.671,0.000111041,EXAC_NFE_AF,TSPEAR
501792,21:45929291:T>C,NR_103707.1:n.1369+2T>C,\N,\N,5/6,Unknown significance,\N,splice_donor_variant&non_coding_transcript_variant,0.011,0.002,1KG_SAS_AF,TSPEAR
501793,21:45929291:TGCAGAGGTGTGGGGGAGCGGGC>T,NR_103707.1:n.1369+64_1369+85del,\N,\N,5/6,Unknown significance,\N,splice_region_variant&intron_variant&non_coding_transcript_variant,7.671,\N,\N,TSPEAR
501794,21:45929298:G>A,NM_144991.2:c.1567-29C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.409,0.0000194962,EXAC_NFE_AF,TSPEAR
501795,21:45929305:G>T,NM_144991.2:c.1567-36C>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.035,0.001,1KG_EUR_AF,TSPEAR
501796,21:45929309:C>G,NM_144991.2:c.1567-40G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.083,0.000132767,EXAC_AMR_AF,TSPEAR
501797,21:45929309:C>T,NM_144991.2:c.1567-40G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.154,0.000552079,EXAC_EAS_AF,TSPEAR
501798,21:45929310:G>A,NM_144991.2:c.1567-41C>T,\N,\N,9/11,Benign,\N,intron_variant,0.054,0.00821238,EXAC_EAS_AF,TSPEAR
501799,21:45929313:C>T,NM_144991.2:c.1567-44G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.885,0.0015,1KG_AFR_AF,TSPEAR
501800,21:45929314:G>A,NM_144991.2:c.1567-45C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.417,0.000320171,EXAC_SAS_AF,TSPEAR
501801,21:45929314:G>C,NM_144991.2:c.1567-45C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.217,0.00116306,EVS_EA_AF,TSPEAR
501802,21:45929321:TGTG>T,NM_144991.2:c.1567-55_1567-53del,\N,\N,9/11,Unknown significance,\N,intron_variant,2.183,0.000192976,EXAC_AFR_AF,TSPEAR
501803,21:45929327:G>T,NM_144991.2:c.1567-58C>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.169,\N,\N,TSPEAR
501804,21:45929331:C>T,NM_144991.2:c.1567-62G>A,\N,\N,9/11,Benign,\N,intron_variant,0.11,0.0151,1KG_AFR_AF,TSPEAR
501805,21:45929332:G>A,NM_144991.2:c.1567-63C>T,\N,\N,9/11,Benign,\N,intron_variant,1.401,0.0151,1KG_AFR_AF,TSPEAR
501806,21:45929353:C>T,NM_144991.2:c.1567-84G>A,\N,\N,9/11,Benign,\N,intron_variant,0.231,0.0136,1KG_AFR_AF,TSPEAR
501807,21:45929353:CGGGCGCAGAGGTGTGGGGGAGGGGGCGCAGAGGTGTGGGGGAGG>C,NM_144991.2:c.1567-128_1567-85del,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
501808,21:45929354:G>A,NM_144991.2:c.1567-85C>T,\N,\N,9/11,Benign,\N,intron_variant,2.975,0.0136,1KG_AFR_AF,TSPEAR
501809,21:45929375:G>C,NM_144991.2:c.1567-106C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.008,\N,\N,TSPEAR
501810,21:45929382:A>G,NM_144991.2:c.1567-113T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.372,\N,\N,TSPEAR
501811,21:45929393:G>T,NM_144991.2:c.1567-124C>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.012,0.002,1KG_SAS_AF,TSPEAR
501812,21:45929397:G>C,NM_144991.2:c.1567-128C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.017,\N,\N,TSPEAR
501813,21:45929417:AGCG>A,NM_144991.2:c.1567-151_1567-149del,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
501814,21:45929418:G>C,NM_144991.2:c.1567-149C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.237,0.003,1KG_EUR_AF,TSPEAR
501815,21:45929419:C>G,NM_144991.2:c.1567-150G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.34,\N,\N,TSPEAR
501816,21:45929424:G>A,NM_144991.2:c.1567-155C>T,\N,\N,9/11,Benign,\N,intron_variant,2.588,0.0348,1KG_AFR_AF,TSPEAR
501817,21:45929437:T>A,NM_144991.2:c.1567-168A>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.542,\N,\N,TSPEAR
501818,21:45929441:C>G,NM_144991.2:c.1567-172G>C,\N,\N,9/11,Benign,\N,intron_variant,2.512,0.0159,1KG_AFR_AF,TSPEAR
501819,21:45929459:A>T,NM_144991.2:c.1567-190T>A,\N,\N,9/11,Benign,\N,intron_variant,0.079,0.0144,1KG_AFR_AF,TSPEAR
501820,21:45929464:G>A,NM_144991.2:c.1567-195C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.674,0.0008,1KG_AFR_AF,TSPEAR
501821,21:45929472:A>G,NM_144991.2:c.1567-203T>C,\N,\N,9/11,Benign,\N,intron_variant,0.184,0.0092,1KG_SAS_AF,TSPEAR
501822,21:45929474:G>C,NM_144991.2:c.1567-205C>G,\N,\N,9/11,Benign,\N,intron_variant,0.137,0.0144,1KG_AMR_AF,TSPEAR
501823,21:45929479:A>G,NM_144991.2:c.1567-210T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.987,0.0045,1KG_AFR_AF,TSPEAR
501824,21:45929481:T>A,NM_144991.2:c.1567-212A>T,\N,\N,9/11,Unknown significance,\N,intron_variant,6.867,0.0038,1KG_AFR_AF,TSPEAR
501825,21:45929506:C>G,NM_144991.2:c.1567-237G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.586,\N,\N,TSPEAR
501826,21:45929551:T>C,NM_144991.2:c.1567-282A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.107,0.001,1KG_SAS_AF,TSPEAR
501827,21:45929555:C>T,NM_144991.2:c.1567-286G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.699,\N,\N,TSPEAR
501828,21:45929570:G>A,NM_144991.2:c.1567-301C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.822,\N,\N,TSPEAR
501829,21:45929573:A>G,NM_144991.2:c.1567-304T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.392,0.0008,1KG_AFR_AF,TSPEAR
501830,21:45929586:C>T,NM_144991.2:c.1567-317G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.695,0.001,1KG_EUR_AF,TSPEAR
501831,21:45929640:A>AGCCCT,NM_144991.2:c.1567-376_1567-372dup,\N,\N,9/11,Benign,\N,intron_variant,0.053,0.0113,1KG_AFR_AF,TSPEAR
501832,21:45929641:G>T,NM_144991.2:c.1567-372C>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.391,0.002,1KG_SAS_AF,TSPEAR
501833,21:45929648:C>T,NM_144991.2:c.1567-379G>A,\N,\N,9/11,Benign,\N,intron_variant,3.941,0.007,1KG_EUR_AF,TSPEAR
501834,21:45929651:T>C,NM_144991.2:c.1567-382A>G,\N,\N,9/11,Benign,\N,intron_variant,0.727,0.0113,1KG_AFR_AF,TSPEAR
501835,21:45929687:A>G,NM_144991.2:c.1567-418T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,2.05,\N,\N,TSPEAR
501836,21:45929691:C>T,NM_144991.2:c.1567-422G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,5.419,0.0041,1KG_SAS_AF,TSPEAR
501837,21:45929693:TCTC>T,NM_144991.2:c.1567-427_1567-425del,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
501838,21:45929727:C>T,NM_144991.2:c.1567-458G>A,\N,\N,9/11,Benign,\N,intron_variant,0.384,0.0439,1KG_AFR_AF,TSPEAR
501839,21:45929746:CA>C,NM_144991.2:c.1567-478del,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
501840,21:45929756:A>G,NM_144991.2:c.1567-487T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,5.477,0.002,1KG_EUR_AF,TSPEAR
501841,21:45929760:A>T,NM_144991.2:c.1567-491T>A,\N,\N,9/11,Unknown significance,\N,intron_variant,6.698,0.001,1KG_EAS_AF,TSPEAR
501842,21:45929784:C>T,NM_144991.2:c.1567-515G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.252,0.0008,1KG_AFR_AF,TSPEAR
501843,21:45929896:C>T,NM_144991.2:c.1567-627G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,5.585,\N,\N,TSPEAR
501844,21:45929915:C>G,NM_144991.2:c.1567-646G>C,\N,\N,9/11,Benign,\N,intron_variant,1.306,0.0098,1KG_AFR_AF,TSPEAR
501845,21:45929916:C>T,NM_144991.2:c.1567-647G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.822,0.001,1KG_EAS_AF,TSPEAR
501846,21:45929941:C>T,NM_144991.2:c.1567-672G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,6.598,0.0014,1KG_AMR_AF,TSPEAR
501847,21:45929946:A>C,NM_144991.2:c.1567-677T>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.742,0.002,1KG_EUR_AF,TSPEAR
501848,21:45929966:T>C,NM_144991.2:c.1567-697A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,2.466,0.001,1KG_EAS_AF,TSPEAR
501849,21:45929972:C>A,NM_144991.2:c.1567-703G>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.586,\N,\N,TSPEAR
501850,21:45929972:C>T,NM_144991.2:c.1567-703G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.433,\N,\N,TSPEAR
501851,21:45929986:C>T,NM_144991.2:c.1567-717G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.13,0.0008,1KG_AFR_AF,TSPEAR
501852,21:45930045:G>A,NM_144991.2:c.1567-776C>T,\N,\N,9/11,Benign,\N,intron_variant,3.183,0.0069,1KG_EAS_AF,TSPEAR
501853,21:45930068:G>A,NM_144991.2:c.1567-799C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,5.052,0.0008,1KG_AFR_AF,TSPEAR
501854,21:45930075:G>C,NM_144991.2:c.1567-806C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.475,0.0008,1KG_AFR_AF,TSPEAR
501855,21:45930091:G>A,NM_144991.2:c.1567-822C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,2.001,\N,\N,TSPEAR
501856,21:45930124:G>GT,NM_144991.2:c.1567-856dup,\N,\N,9/11,Benign,\N,intron_variant,0.468,0.0119,1KG_EUR_AF,TSPEAR
501857,21:45930136:C>T,NM_144991.2:c.1567-867G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,4.314,\N,\N,TSPEAR
501858,21:45930137:G>A,NM_144991.2:c.1567-868C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,5.057,0.001,1KG_EAS_AF,TSPEAR
501859,21:45930157:C>T,NM_144991.2:c.1567-888G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,5.263,\N,\N,TSPEAR
501860,21:45930204:G>C,NM_144991.2:c.1567-935C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.648,\N,\N,TSPEAR
501861,21:45930216:C>G,NM_144991.2:c.1567-947G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,5.551,\N,\N,TSPEAR
501862,21:45930219:A>G,NM_144991.2:c.1567-950T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,1.302,\N,\N,TSPEAR
501863,21:45930228:C>T,NM_144991.2:c.1567-959G>A,\N,\N,9/11,Benign,\N,intron_variant,6.952,0.0129,1KG_AFR_AF,TSPEAR
501864,21:45930241:G>A,NM_144991.2:c.1567-972C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,4.31,\N,\N,TSPEAR
501865,21:45930247:G>A,NM_144991.2:c.1567-978C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.942,0.0031,1KG_SAS_AF,TSPEAR
501866,21:45930262:C>T,NM_144991.2:c.1567-993G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,5.382,\N,\N,TSPEAR
501867,21:45930263:G>C,NM_144991.2:c.1567-994C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.179,\N,\N,TSPEAR
501868,21:45930276:A>G,NM_144991.2:c.1567-1007T>C,\N,\N,9/11,Benign,\N,intron_variant,1.766,0.0643,1KG_AFR_AF,TSPEAR
501869,21:45930291:C>T,NM_144991.2:c.1567-1022G>A,\N,\N,9/11,Benign,\N,intron_variant,5.017,0.0303,1KG_AFR_AF,TSPEAR
501870,21:45930308:A>G,NM_144991.2:c.1567-1039T>C,\N,\N,9/11,Benign,\N,intron_variant,1.831,0.0144,1KG_AFR_AF,TSPEAR
501871,21:45930316:G>C,NM_144991.2:c.1567-1047C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.8,\N,\N,TSPEAR
501872,21:45930322:T>C,NM_144991.2:c.1567-1053A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.572,\N,\N,TSPEAR
501873,21:45930335:C>T,NM_144991.2:c.1567-1066G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.518,\N,\N,TSPEAR
501874,21:45930336:G>A,NM_144991.2:c.1567-1067C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.922,\N,\N,TSPEAR
501875,21:45930337:A>G,NM_144991.2:c.1567-1068T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,6.545,0.001,1KG_EAS_AF,TSPEAR
501876,21:45930344:A>G,NM_144991.2:c.1567-1075T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,1.952,0.0008,1KG_AFR_AF,TSPEAR
501877,21:45930384:C>T,NM_144991.2:c.1567-1115G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,5.415,0.0008,1KG_AFR_AF,TSPEAR
501878,21:45930388:C>T,NM_144991.2:c.1567-1119G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.014,0.0031,1KG_SAS_AF,TSPEAR
501879,21:45930402:C>T,NM_144991.2:c.1567-1133G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.689,0.0029,1KG_AMR_AF,TSPEAR
501880,21:45930422:C>T,NM_144991.2:c.1567-1153G>A,\N,\N,9/11,Benign,\N,intron_variant,6.342,0.1551,1KG_AFR_AF,TSPEAR
501881,21:45930446:C>T,NM_144991.2:c.1567-1177G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,4.767,\N,\N,TSPEAR
501882,21:45930461:A>ACTGTCCGGCGCCTGC,NM_144991.2:c.1567-1207_1567-1193dup,\N,\N,9/11,Benign,\N,intron_variant,0.282,0.0303,1KG_AFR_AF,TSPEAR
501883,21:45930461:A>ACTGTCCGGCGCCTGT,NM_144991.2:c.1567-1193_1567-1192insACAGGCGCCGGACAG,\N,\N,9/11,Benign,\N,intron_variant,0.282,0.0068,1KG_AFR_AF,TSPEAR
501884,21:45930471:G>C,NM_144991.2:c.1567-1202C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,1.048,\N,\N,TSPEAR
501885,21:45930484:G>T,NM_144991.2:c.1567-1215C>A,\N,\N,9/11,Benign,\N,intron_variant,2.136,0.0208,1KG_EAS_AF,TSPEAR
501886,21:45930494:T>A,NM_144991.2:c.1567-1225A>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.909,\N,\N,TSPEAR
501887,21:45930519:C>T,NM_144991.2:c.1567-1250G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.668,0.002,1KG_EAS_AF,TSPEAR
501888,21:45930525:C>T,NM_144991.2:c.1567-1256G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.393,\N,\N,TSPEAR
501889,21:45930532:C>T,NM_144991.2:c.1567-1263G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,6.614,\N,\N,TSPEAR
501890,21:45930533:G>T,NM_144991.2:c.1567-1264C>A,\N,\N,9/11,Benign,\N,intron_variant,1.348,0.0051,1KG_SAS_AF,TSPEAR
501891,21:45930562:G>A,NM_144991.2:c.1567-1293C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,5.122,\N,\N,TSPEAR
501892,21:45930566:G>A,NM_144991.2:c.1567-1297C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,2.447,\N,\N,TSPEAR
501893,21:45930611:G>T,NM_144991.2:c.1567-1342C>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.458,0.0029,1KG_AMR_AF,TSPEAR
501894,21:45930624:C>T,NM_144991.2:c.1567-1355G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,8.014,\N,\N,TSPEAR
501895,21:45930635:G>A,NM_144991.2:c.1567-1366C>T,\N,\N,9/11,Benign,\N,intron_variant,2.722,0.3559,1KG_AMR_AF,TSPEAR
501896,21:45930642:T>C,NM_144991.2:c.1567-1373A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,1.178,0.0008,1KG_AFR_AF,TSPEAR
501897,21:45930645:C>T,NM_144991.2:c.1567-1376G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,6.051,\N,\N,TSPEAR
501898,21:45930653:A>C,NM_144991.2:c.1567-1384T>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.513,\N,\N,TSPEAR
501899,21:45930662:C>T,NM_144991.2:c.1567-1393G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.504,0.001,1KG_EAS_AF,TSPEAR
501900,21:45930675:G>A,NM_144991.2:c.1567-1406C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,4.661,0.0015,1KG_AFR_AF,TSPEAR
501901,21:45930676:C>T,NM_144991.2:c.1567-1407G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,6.839,0.0008,1KG_AFR_AF,TSPEAR
501902,21:45930703:C>T,NM_144991.2:c.1567-1434G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.833,0.001,1KG_EUR_AF,TSPEAR
501903,21:45930709:T>A,NM_144991.2:c.1567-1440A>T,\N,\N,9/11,Unknown significance,\N,intron_variant,6.199,0.0008,1KG_AFR_AF,TSPEAR
501904,21:45930744:G>A,NM_144991.2:c.1567-1475C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.574,0.0008,1KG_AFR_AF,TSPEAR
501905,21:45930746:C>T,NM_144991.2:c.1567-1477G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,7.059,\N,\N,TSPEAR
501906,21:45930760:C>T,NM_144991.2:c.1567-1491G>A,\N,\N,9/11,Benign,\N,intron_variant,0.243,0.0082,1KG_SAS_AF,TSPEAR
501907,21:45930770:G>A,NM_144991.2:c.1567-1501C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.099,\N,\N,TSPEAR
501908,21:45930777:G>A,NM_144991.2:c.1567-1508C>T,\N,\N,9/11,Benign,\N,intron_variant,2.908,0.0069,1KG_EAS_AF,TSPEAR
501909,21:45930796:G>C,NM_144991.2:c.1567-1527C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,1.108,\N,\N,TSPEAR
501910,21:45930802:C>G,NM_144991.2:c.1567-1533G>C,\N,\N,9/11,Benign,\N,intron_variant,4.281,0.1021,1KG_AFR_AF,TSPEAR
501911,21:45930802:C>T,NM_144991.2:c.1567-1533G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,6.459,\N,\N,TSPEAR
501912,21:45930849:G>A,NM_144991.2:c.1567-1580C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,4.657,0.0014,1KG_AMR_AF,TSPEAR
501913,21:45930862:C>T,NM_144991.2:c.1567-1593G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,4.967,0.0014,1KG_AMR_AF,TSPEAR
501914,21:45930867:A>G,NM_144991.2:c.1567-1598T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.855,0.0014,1KG_AMR_AF,TSPEAR
501915,21:45930879:C>T,NM_144991.2:c.1567-1610G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.702,\N,\N,TSPEAR
501916,21:45930880:G>A,NM_144991.2:c.1567-1611C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.447,0.001,1KG_EAS_AF|1KG_SAS_AF,TSPEAR
501917,21:45930903:ACT>A,NM_144991.2:c.1567-1636_1567-1635del,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
501918,21:45930912:C>T,NM_144991.2:c.1567-1643G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,7.568,\N,\N,TSPEAR
501919,21:45930913:G>A,NM_144991.2:c.1567-1644C>T,\N,\N,9/11,Benign,\N,intron_variant,2.377,0.0113,1KG_AFR_AF,TSPEAR
501920,21:45930914:G>A,NM_144991.2:c.1567-1645C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,4.69,0.001,1KG_EAS_AF,TSPEAR
501921,21:45930944:C>T,NM_144991.2:c.1567-1675G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.953,\N,\N,TSPEAR
501922,21:45930954:G>C,NM_144991.2:c.1567-1685C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.865,\N,\N,TSPEAR
501923,21:45930959:G>A,NM_144991.2:c.1567-1690C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.73,\N,\N,TSPEAR
501924,21:45930960:C>CG,NM_144991.2:c.1567-1692dup,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,0.002,1KG_EAS_AF,TSPEAR
501925,21:45930961:G>C,NM_144991.2:c.1567-1692C>G,\N,\N,9/11,Benign,\N,intron_variant,0.309,0.0658,1KG_AFR_AF,TSPEAR
501926,21:45930963:G>C,NM_144991.2:c.1567-1694C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.442,0.0008,1KG_AFR_AF,TSPEAR
501927,21:45930977:C>T,NM_144991.2:c.1567-1708G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,6.941,0.002,1KG_SAS_AF,TSPEAR
501928,21:45931034:C>T,NM_144991.2:c.1567-1765G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,5.251,\N,\N,TSPEAR
501929,21:45931079:C>T,NM_144991.2:c.1567-1810G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,4.989,\N,\N,TSPEAR
501930,21:45931101:GCCTGCACACA>G,NM_144991.2:c.1567-1842_1567-1833del,\N,\N,9/11,Benign,\N,intron_variant,7.101,0.0119,1KG_EUR_AF,TSPEAR
501931,21:45931112:CCTG>C,NM_144991.2:c.1567-1846_1567-1844del,\N,\N,9/11,Unknown significance,\N,intron_variant,3.874,0.003,1KG_AFR_AF,TSPEAR
501932,21:45931113:CTGCACACACA>C,NM_144991.2:c.1567-1854_1567-1845del,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
501933,21:45931117:A>C,NM_144991.2:c.1567-1848T>G,\N,\N,9/11,Benign,\N,intron_variant,6.712,0.0164,1KG_SAS_AF,TSPEAR
501934,21:45931118:C>T,NM_144991.2:c.1567-1849G>A,\N,\N,9/11,Benign,\N,intron_variant,8.051,0.0174,1KG_AFR_AF,TSPEAR
501935,21:45931123:A>C,NM_144991.2:c.1567-1854T>G,\N,\N,9/11,Unknown significance,\N,intron_variant,6.61,\N,\N,TSPEAR
501936,21:45931128:C>T,NM_144991.2:c.1567-1859G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,9.326,\N,\N,TSPEAR
501937,21:45931141:C>T,NM_144991.2:c.1567-1872G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,7.564,\N,\N,TSPEAR
501938,21:45931143:G>T,NM_144991.2:c.1567-1874C>A,\N,\N,9/11,Unknown significance,\N,intron_variant,4.118,\N,\N,TSPEAR
501939,21:45931151:GCATA>G,NM_144991.2:c.1567-1886_1567-1883del,\N,\N,9/11,Benign,\N,intron_variant,8.352,0.0109,1KG_EUR_AF,TSPEAR
501940,21:45931158:TACAC>T,NM_144991.2:c.1567-1893_1567-1890del,\N,\N,9/11,Unknown significance,\N,intron_variant,8.644,\N,\N,TSPEAR
501941,21:45931162:C>T,NM_144991.2:c.1567-1893G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,6.645,\N,\N,TSPEAR
501942,21:45931183:C>T,NM_144991.2:c.1567-1914G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.727,0.0041,1KG_SAS_AF,TSPEAR
501943,21:45931184:G>A,NM_144991.2:c.1567-1915C>T,\N,\N,9/11,Benign,\N,intron_variant,1.814,0.0109,1KG_EUR_AF,TSPEAR
501944,21:45931184:GCA>G,NM_144991.2:c.1567-1917_1567-1916del,\N,\N,9/11,Unknown significance,\N,intron_variant,3.024,\N,\N,TSPEAR
501945,21:45931186:A>G,NM_144991.2:c.1567-1917T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.775,0.0031,1KG_SAS_AF,TSPEAR
501946,21:45931188:A>G,NM_144991.2:c.1567-1919T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,3.368,\N,\N,TSPEAR
501947,21:45931194:A>C,NM_144991.2:c.1567-1925T>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.6,\N,\N,TSPEAR
501948,21:45931199:C>T,NM_144991.2:c.1567-1930G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.713,0.0023,1KG_AFR_AF,TSPEAR
501949,21:45931200:G>A,NM_144991.2:c.1567-1931C>T,\N,\N,9/11,Benign,\N,intron_variant,0.071,0.0318,1KG_AFR_AF,TSPEAR
501950,21:45931202:CTGCA>C,NM_144991.2:c.1567-1937_1567-1934del,\N,\N,9/11,Unknown significance,\N,intron_variant,5.369,0.003,1KG_EUR_AF,TSPEAR
501951,21:45931202:CTGCATGCA>C,NM_144991.2:c.1567-1941_1567-1934del,\N,\N,9/11,Unknown significance,\N,intron_variant,5.051,\N,\N,TSPEAR
501952,21:45931204:G>A,NM_144991.2:c.1567-1935C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,2.309,\N,\N,TSPEAR
501953,21:45931209:C>T,NM_144991.2:c.1567-1940G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.027,0.0008,1KG_AFR_AF,TSPEAR
501954,21:45931215:TAC>T,NM_144991.2:c.1567-1948_1567-1947del,\N,\N,9/11,Unknown significance,\N,intron_variant,5.626,\N,\N,TSPEAR
501955,21:45931215:TACAC>T,NM_144991.2:c.1567-1950_1567-1947del,\N,\N,9/11,Unknown significance,\N,intron_variant,6.04,\N,\N,TSPEAR
501956,21:45931216:A>G,NM_144991.2:c.1567-1947T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,2.375,0.0038,1KG_AFR_AF,TSPEAR
501957,21:45931219:C>T,NM_144991.2:c.1567-1950G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.907,0.0038,1KG_AFR_AF,TSPEAR
501958,21:45931237:C>T,NM_144991.2:c.1567-1968G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.966,0.001,1KG_SAS_AF,TSPEAR
501959,21:45931238:A>G,NM_144991.2:c.1567-1969T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,2.994,\N,\N,TSPEAR
501960,21:45931244:TAC>T,NM_144991.2:c.1567-1977_1567-1976del,\N,\N,9/11,Benign,\N,intron_variant,5.935,0.0149,1KG_EUR_AF,TSPEAR
501961,21:45931244:TACAC>T,NM_144991.2:c.1567-1979_1567-1976del,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,0.0015,1KG_AFR_AF,TSPEAR
501962,21:45931250:C>T,NM_144991.2:c.1567-1981G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.466,\N,\N,TSPEAR
501963,21:45931253:A>ACACACAGG,NM_144991.2:c.1567-1985_1567-1984insCCTGTGTG,\N,\N,9/11,Benign,\N,intron_variant,0.151,0.0688,1KG_AFR_AF,TSPEAR
501964,21:45931253:A>ACACAGG,NM_144991.2:c.1567-1985_1567-1984insCCTGTG,\N,\N,9/11,Benign,\N,intron_variant,0.181,0.0303,1KG_AFR_AF,TSPEAR
501965,21:45931253:A>ACAGG,NM_144991.2:c.1567-1985_1567-1984insCCTG,\N,\N,9/11,Benign,\N,intron_variant,0.217,0.0492,1KG_AFR_AF,TSPEAR
501966,21:45931253:A>AGG,NM_144991.2:c.1567-1985_1567-1984insCC,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
501967,21:45931254:CAT>C,NM_144991.2:c.1567-1987_1567-1986del,\N,\N,9/11,Unknown significance,\N,intron_variant,5.764,\N,\N,TSPEAR
501968,21:45931255:AT>CACAGGCA,NM_144991.2:c.1567-1987_1567-1986delinsTGCCTGTG,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
501969,21:45931255:AT>CAGGCA,NM_144991.2:c.1567-1987_1567-1986delinsTGCCTG,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
501970,21:45931255:AT>GGCA,NM_144991.2:c.1567-1987_1567-1986delinsTGCC,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
501971,21:45931256:T>C,NM_144991.2:c.1567-1987A>G,\N,\N,9/11,Benign,\N,intron_variant,0.249,0.0098,1KG_AFR_AF,TSPEAR
501972,21:45931266:C>T,NM_144991.2:c.1567-1997G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.439,0.0008,1KG_AFR_AF,TSPEAR
501973,21:45931274:CATGCACAG>C,NM_144991.2:c.1567-2013_1567-2006del,\N,\N,9/11,Unknown significance,\N,intron_variant,6.745,0.0023,1KG_AFR_AF,TSPEAR
501974,21:45931288:C>T,NM_144991.2:c.1567-2019G>A,\N,\N,9/11,Benign,\N,intron_variant,2.002,0.0139,1KG_EUR_AF,TSPEAR
501975,21:45931294:T>A,NM_144991.2:c.1567-2025A>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.511,0.001,1KG_EAS_AF,TSPEAR
501976,21:45931303:A>C,NM_144991.2:c.1567-2034T>G,\N,\N,9/11,Unknown significance,\N,intron_variant,1.49,\N,\N,TSPEAR
501977,21:45931304:C>A,NM_144991.2:c.1567-2035G>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.508,0.0008,1KG_AFR_AF,TSPEAR
501978,21:45931315:A>T,NM_144991.2:c.1567-2046T>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.922,\N,\N,TSPEAR
501979,21:45931324:T>A,NM_144991.2:c.1567-2055A>T,\N,\N,9/11,Benign,\N,intron_variant,4.895,0.0053,1KG_AFR_AF,TSPEAR
501980,21:45931332:C>T,NM_144991.2:c.1567-2063G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.865,0.0008,1KG_AFR_AF,TSPEAR
501981,21:45931349:A>G,NM_144991.2:c.1567-2080T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,2.225,0.001,1KG_EUR_AF,TSPEAR
501982,21:45931362:TAC>T,NM_144991.2:c.1567-2095_1567-2094del,\N,\N,9/11,Unknown significance,\N,intron_variant,3.483,\N,\N,TSPEAR
501983,21:45931370:C>T,NM_144991.2:c.1567-2101G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.071,0.001,1KG_EAS_AF,TSPEAR
501984,21:45931370:CGTAT>C,NM_144991.2:c.1567-2105_1567-2102del,\N,\N,9/11,Unknown significance,\N,intron_variant,4.583,\N,\N,TSPEAR
501985,21:45931371:G>A,NM_144991.2:c.1567-2102C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.782,0.001,1KG_EAS_AF,TSPEAR
501986,21:45931372:T>C,NM_144991.2:c.1567-2103A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,1.166,\N,\N,TSPEAR
501987,21:45931376:TATGC>T,NM_144991.2:c.1567-2111_1567-2108del,\N,\N,9/11,Unknown significance,\N,intron_variant,6.654,\N,\N,TSPEAR
501988,21:45931382:T>G,NM_144991.2:c.1567-2113A>C,\N,\N,9/11,Unknown significance,\N,intron_variant,3.074,0.0008,1KG_AFR_AF,TSPEAR
501989,21:45931388:C>T,NM_144991.2:c.1567-2119G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.309,0.002,1KG_EAS_AF,TSPEAR
501990,21:45931392:C>A,NM_144991.2:c.1567-2123G>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.511,\N,\N,TSPEAR
501991,21:45931402:C>T,NM_144991.2:c.1567-2133G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.646,0.001,1KG_EUR_AF,TSPEAR
501992,21:45931418:T>C,NM_144991.2:c.1567-2149A>G,\N,\N,9/11,Benign,\N,intron_variant,6.641,0.0082,1KG_SAS_AF,TSPEAR
501993,21:45931429:A>G,NM_144991.2:c.1567-2160T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,6.754,\N,\N,TSPEAR
501994,21:45931430:T>G,NM_144991.2:c.1567-2161A>C,\N,\N,9/11,Benign,\N,intron_variant,7.931,0.0113,1KG_AFR_AF,TSPEAR
501995,21:45931432:C>T,NM_144991.2:c.1567-2163G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,8.152,0.001,1KG_SAS_AF,TSPEAR
501996,21:45931440:C>T,NM_144991.2:c.1567-2171G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.35,0.001,1KG_EAS_AF,TSPEAR
501997,21:45931463:C>A,NM_144991.2:c.1567-2194G>T,\N,\N,9/11,Benign,\N,intron_variant,6.523,0.1611,1KG_AFR_AF,TSPEAR
501998,21:45931463:C>T,NM_144991.2:c.1567-2194G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,5.665,\N,\N,TSPEAR
501999,21:45931472:C>T,NM_144991.2:c.1567-2203G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.455,0.0014,1KG_AMR_AF,TSPEAR
502000,21:45931497:C>T,NM_144991.2:c.1567-2228G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.484,0.0015,1KG_AFR_AF,TSPEAR
502001,21:45931505:C>T,NM_144991.2:c.1567-2236G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.996,0.001,1KG_EAS_AF,TSPEAR
502002,21:45931522:C>T,NM_144991.2:c.1567-2253G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,4.155,\N,\N,TSPEAR
502003,21:45931530:G>T,NM_144991.2:c.1567-2261C>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.508,0.001,1KG_SAS_AF,TSPEAR
502004,21:45931546:GAC>G,NM_144991.2:c.1567-2279_1567-2278del,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
502005,21:45931552:C>T,NM_144991.2:c.1567-2283G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.022,0.0008,1KG_AFR_AF,TSPEAR
502006,21:45931557:C>T,NM_144991.2:c.1567-2288G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.826,\N,\N,TSPEAR
502007,21:45931564:T>G,NM_144991.2:c.1567-2295A>C,\N,\N,9/11,Unknown significance,\N,intron_variant,2.974,0.001,1KG_EUR_AF,TSPEAR
502008,21:45931584:C>T,NM_144991.2:c.1567-2315G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.66,0.0023,1KG_AFR_AF,TSPEAR
502009,21:45931585:C>T,NM_144991.2:c.1567-2316G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.899,0.0008,1KG_AFR_AF,TSPEAR
502010,21:45931637:T>A,NM_144991.2:c.1567-2368A>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.161,\N,\N,TSPEAR
502011,21:45931645:C>T,NM_144991.2:c.1567-2376G>A,\N,\N,9/11,Benign,\N,intron_variant,0.338,0.0053,1KG_AFR_AF,TSPEAR
502012,21:45931646:G>A,NM_144991.2:c.1567-2377C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.694,\N,\N,TSPEAR
502013,21:45931659:C>T,NM_144991.2:c.1567-2390G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,5.972,0.0023,1KG_AFR_AF,TSPEAR
502014,21:45931669:C>T,NM_144991.2:c.1567-2400G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.377,0.001,1KG_EUR_AF,TSPEAR
502015,21:45931682:G>GGCCCGGAGT,NM_144991.2:c.1567-2422_1567-2414dup,\N,\N,9/11,Unknown significance,\N,intron_variant,0.257,0.0031,1KG_SAS_AF,TSPEAR
502016,21:45931686:C>T,NM_144991.2:c.1567-2417G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.273,\N,\N,TSPEAR
502017,21:45931696:G>A,NM_144991.2:c.1567-2427C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,2.201,\N,\N,TSPEAR
502018,21:45931711:A>AG,NM_144991.2:c.1567-2443dup,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
502019,21:45931711:AG>A,NM_144991.2:c.1567-2443del,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
502020,21:45931718:T>G,NM_144991.2:c.1567-2449A>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.32,0.001,1KG_EAS_AF,TSPEAR
502021,21:45931744:A>G,NM_144991.2:c.1567-2475T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,2.602,\N,\N,TSPEAR
502022,21:45931746:T>C,NM_144991.2:c.1567-2477A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,1.088,0.0015,1KG_AFR_AF,TSPEAR
502023,21:45931777:C>T,NM_144991.2:c.1567-2508G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.23,0.0015,1KG_AFR_AF,TSPEAR
502024,21:45931783:C>T,NM_144991.2:c.1567-2514G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,4.211,\N,\N,TSPEAR
502025,21:45931784:G>A,NM_144991.2:c.1567-2515C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.615,\N,\N,TSPEAR
502026,21:45931825:C>T,NM_144991.2:c.1567-2556G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,6.848,\N,\N,TSPEAR
502027,21:45931840:A>T,NM_144991.2:c.1567-2571T>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.834,\N,\N,TSPEAR
502028,21:45931860:G>A,NM_144991.2:c.1567-2591C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.504,0.002,1KG_EAS_AF,TSPEAR
502029,21:45931865:TGGAG>T,NM_144991.2:c.1567-2600_1567-2597del,\N,\N,9/11,Benign,\N,intron_variant,4.918,0.1157,1KG_AFR_AF,TSPEAR
502030,21:45931878:C>T,NM_144991.2:c.1567-2609G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.108,0.0014,1KG_AMR_AF,TSPEAR
502031,21:45931894:CAG>C,NM_144991.2:c.1567-2627_1567-2626del,\N,\N,9/11,Benign,\N,intron_variant,9.584,0.006,1KG_EAS_AF,TSPEAR
502032,21:45931898:G>A,NM_144991.2:c.1567-2629C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,2.014,0.0008,1KG_AFR_AF,TSPEAR
502033,21:45931903:A>G,NM_144991.2:c.1567-2634T>C,\N,\N,9/11,Benign,\N,intron_variant,2.304,0.087,1KG_AFR_AF,TSPEAR
502034,21:45931914:G>C,NM_144991.2:c.1567-2645C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,1.058,0.0038,1KG_AFR_AF,TSPEAR
502035,21:45931924:C>T,NM_144991.2:c.1567-2655G>A,\N,\N,9/11,Benign,\N,intron_variant,1.45,0.0219,1KG_AFR_AF,TSPEAR
502036,21:45931936:T>C,NM_144991.2:c.1567-2667A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.715,0.0014,1KG_AMR_AF,TSPEAR
502037,21:45931939:G>C,NM_144991.2:c.1567-2670C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,2.055,\N,\N,TSPEAR
502038,21:45931983:G>A,NM_144991.2:c.1567-2714C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,9.83,0.0008,1KG_AFR_AF,TSPEAR
502039,21:45931987:G>C,NM_144991.2:c.1567-2718C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.202,\N,\N,TSPEAR
502040,21:45932002:G>A,NM_144991.2:c.1567-2733C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,7.495,\N,\N,TSPEAR
502041,21:45932022:G>A,NM_144991.2:c.1567-2753C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.292,\N,\N,TSPEAR
502042,21:45932029:G>C,NM_144991.2:c.1567-2760C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.587,\N,\N,TSPEAR
502043,21:45932034:C>T,NM_144991.2:c.1567-2765G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.09,0.001,1KG_SAS_AF,TSPEAR
502044,21:45932043:G>A,NM_144991.2:c.1567-2774C>T,\N,\N,9/11,Benign,\N,intron_variant,1.766,0.0109,1KG_EUR_AF,TSPEAR
502045,21:45932051:C>T,NM_144991.2:c.1567-2782G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.491,0.003,1KG_AFR_AF,TSPEAR
502046,21:45932071:G>GT,NM_144991.2:c.1567-2803_1567-2802insA,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
502047,21:45932093:C>T,NM_144991.2:c.1567-2824G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,4.584,0.0008,1KG_AFR_AF,TSPEAR
502048,21:45932116:C>T,NM_144991.2:c.1567-2847G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,6.005,0.0038,1KG_AFR_AF,TSPEAR
502049,21:45932117:G>A,NM_144991.2:c.1567-2848C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.883,0.0015,1KG_AFR_AF,TSPEAR
502050,21:45932122:A>C,NM_144991.2:c.1567-2853T>G,\N,\N,9/11,Unknown significance,\N,intron_variant,3.656,\N,\N,TSPEAR
502051,21:45932138:CGAG>C,NM_144991.2:c.1567-2872_1567-2870del,\N,\N,9/11,Benign,\N,intron_variant,4.26,0.0144,1KG_AFR_AF,TSPEAR
502052,21:45932143:A>T,NM_144991.2:c.1567-2874T>A,\N,\N,9/11,Benign,\N,intron_variant,3.011,0.0144,1KG_AFR_AF,TSPEAR
502053,21:45932186:G>T,NM_144991.2:c.1567-2917C>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.476,\N,\N,TSPEAR
502054,21:45932190:G>A,NM_144991.2:c.1567-2921C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,5.878,\N,\N,TSPEAR
502055,21:45932219:T>TGGGGG,NM_144991.2:c.1567-2955_1567-2951dup,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
502056,21:45932220:G>GGGGGT,NM_144991.2:c.1567-2956_1567-2952dup,\N,\N,9/11,Unknown significance,\N,intron_variant,4.137,\N,\N,TSPEAR
502057,21:45932230:T>C,NM_144991.2:c.1567-2961A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.859,0.0008,1KG_AFR_AF,TSPEAR
502058,21:45932237:G>T,NM_144991.2:c.1567-2968C>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.33,0.003,1KG_EUR_AF,TSPEAR
502059,21:45932270:G>A,NM_144991.2:c.1567-3001C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,4.022,0.002,1KG_EAS_AF,TSPEAR
502060,21:45932274:TTGGAGACAGGCTTC>T,NM_144991.2:c.1567-3019_1567-3006del,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
502061,21:45932295:C>T,NM_144991.2:c.1567-3026G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,11.8,\N,\N,TSPEAR
502062,21:45932318:C>T,NM_144991.2:c.1567-3049G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,10.51,\N,\N,TSPEAR
502063,21:45932323:G>A,NM_144991.2:c.1567-3054C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,11.22,\N,\N,TSPEAR
502064,21:45932330:G>GA,NM_144991.2:c.1567-3062dup,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
502065,21:45932333:A>G,NM_144991.2:c.1567-3064T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,8.871,0.001,1KG_EUR_AF,TSPEAR
502066,21:45932335:G>C,NM_144991.2:c.1567-3066C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,3.717,0.002,1KG_EAS_AF,TSPEAR
502067,21:45932348:CCACT>C,NM_144991.2:c.1567-3083_1567-3080del,\N,\N,9/11,Unknown significance,\N,intron_variant,5.403,\N,\N,TSPEAR
502068,21:45932361:C>G,NM_144991.2:c.1567-3092G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.504,\N,\N,TSPEAR
502069,21:45932362:T>C,NM_144991.2:c.1567-3093A>G,\N,\N,9/11,Benign,\N,intron_variant,0.13,0.0401,1KG_AFR_AF,TSPEAR
502070,21:45932366:A>G,NM_144991.2:c.1567-3097T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,2.384,0.0008,1KG_AFR_AF,TSPEAR
502071,21:45932375:G>A,NM_144991.2:c.1567-3106C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,4.022,0.0015,1KG_AFR_AF,TSPEAR
502072,21:45932391:G>A,NM_144991.2:c.1567-3122C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,6.96,0.0008,1KG_AFR_AF,TSPEAR
502073,21:45932433:G>A,NM_144991.2:c.1567-3164C>T,\N,\N,9/11,Benign,\N,intron_variant,4.659,0.0229,1KG_EUR_AF,TSPEAR
502074,21:45932434:T>G,NM_144991.2:c.1567-3165A>C,\N,\N,9/11,Unknown significance,\N,intron_variant,5.776,\N,\N,TSPEAR
502075,21:45932441:G>A,NM_144991.2:c.1567-3172C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,5.996,0.0023,1KG_AFR_AF,TSPEAR
502076,21:45932460:C>T,NM_144991.2:c.1567-3191G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,8.102,\N,\N,TSPEAR
502077,21:45932467:C>T,NM_144991.2:c.1567-3198G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,7.159,\N,\N,TSPEAR
502078,21:45932475:G>A,NM_144991.2:c.1567-3206C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,6.802,0.001,1KG_SAS_AF,TSPEAR
502079,21:45932476:G>T,NM_144991.2:c.1567-3207C>A,\N,\N,9/11,Unknown significance,\N,intron_variant,4.581,0.003,1KG_AFR_AF,TSPEAR
502080,21:45932485:C>T,NM_144991.2:c.1567-3216G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.028,0.0008,1KG_AFR_AF,TSPEAR
502081,21:45932501:C>T,NM_144991.2:c.1567-3232G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.311,0.001,1KG_SAS_AF,TSPEAR
502082,21:45932506:C>T,NM_144991.2:c.1567-3237G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.768,0.001,1KG_EAS_AF,TSPEAR
502083,21:45932507:G>A,NM_144991.2:c.1567-3238C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,4.132,0.0023,1KG_AFR_AF,TSPEAR
502084,21:45932514:C>T,NM_144991.2:c.1567-3245G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,4.463,0.0045,1KG_AFR_AF,TSPEAR
502085,21:45932540:C>G,NM_144991.2:c.1567-3271G>C,\N,\N,9/11,Benign,\N,intron_variant,3.123,0.0051,1KG_SAS_AF,TSPEAR
502086,21:45932555:G>A,NM_144991.2:c.1567-3286C>T,\N,\N,9/11,Benign,\N,intron_variant,4.014,0.0209,1KG_EUR_AF,TSPEAR
502087,21:45932556:C>T,NM_144991.2:c.1567-3287G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,8.045,0.004,1KG_EAS_AF,TSPEAR
502088,21:45932558:G>C,NM_144991.2:c.1567-3289C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,4.871,\N,\N,TSPEAR
502089,21:45932571:C>T,NM_144991.2:c.1567-3302G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.689,0.0008,1KG_AFR_AF,TSPEAR
502090,21:45932572:G>A,NM_144991.2:c.1567-3303C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.686,0.001,1KG_SAS_AF,TSPEAR
502091,21:45932593:C>A,NM_144991.2:c.1567-3324G>T,\N,\N,9/11,Unknown significance,\N,intron_variant,4.585,\N,\N,TSPEAR
502092,21:45932618:G>A,NM_144991.2:c.1567-3349C>T,\N,\N,9/11,Benign,\N,intron_variant,1.447,0.0204,1KG_AFR_AF,TSPEAR
502093,21:45932633:C>T,NM_144991.2:c.1567-3364G>A,\N,\N,9/11,Benign,\N,intron_variant,0.346,0.0129,1KG_AFR_AF,TSPEAR
502094,21:45932636:G>C,NM_144991.2:c.1567-3367C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.168,0.001,1KG_EUR_AF,TSPEAR
502095,21:45932658:G>A,NM_144991.2:c.1567-3389C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.16,\N,\N,TSPEAR
502096,21:45932667:G>A,NM_144991.2:c.1567-3398C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,5.197,\N,\N,TSPEAR
502097,21:45932709:C>T,NM_144991.2:c.1567-3440G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.479,0.002,1KG_EUR_AF,TSPEAR
502098,21:45932710:G>A,NM_144991.2:c.1567-3441C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.915,\N,\N,TSPEAR
502099,21:45932738:G>C,NM_144991.2:c.1567-3469C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.242,0.0045,1KG_AFR_AF,TSPEAR
502100,21:45932749:C>T,NM_144991.2:c.1567-3480G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.131,0.0014,1KG_AMR_AF,TSPEAR
502101,21:45932750:G>A,NM_144991.2:c.1567-3481C>T,\N,\N,9/11,Benign,\N,intron_variant,0.215,0.005,1KG_EAS_AF,TSPEAR
502102,21:45932756:G>C,NM_144991.2:c.1567-3487C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.207,0.0045,1KG_AFR_AF,TSPEAR
502103,21:45932767:G>T,NM_144991.2:c.1567-3498C>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.634,0.0045,1KG_AFR_AF,TSPEAR
502104,21:45932783:C>G,NM_144991.2:c.1567-3514G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,3.494,0.0045,1KG_AFR_AF,TSPEAR
502105,21:45932797:C>T,NM_144991.2:c.1567-3528G>A,\N,\N,9/11,Benign,\N,intron_variant,0.989,0.0129,1KG_EAS_AF,TSPEAR
502106,21:45932798:G>A,NM_144991.2:c.1567-3529C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.035,\N,\N,TSPEAR
502107,21:45932804:G>A,NM_144991.2:c.1567-3535C>T,\N,\N,9/11,Benign,\N,intron_variant,0.856,0.028,1KG_AFR_AF,TSPEAR
502108,21:45932848:C>G,NM_144991.2:c.1567-3579G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,3.092,\N,\N,TSPEAR
502109,21:45932877:C>T,NM_144991.2:c.1567-3608G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.175,\N,\N,TSPEAR
502110,21:45932886:C>T,NM_144991.2:c.1567-3617G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.614,0.0014,1KG_AMR_AF,TSPEAR
502111,21:45932910:C>T,NM_144991.2:c.1567-3641G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.134,0.001,1KG_EUR_AF,TSPEAR
502112,21:45932919:C>G,NM_144991.2:c.1567-3650G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.378,\N,\N,TSPEAR
502113,21:45932923:A>C,NM_144991.2:c.1567-3654T>G,\N,\N,9/11,Benign,\N,intron_variant,0.773,0.0189,1KG_EUR_AF,TSPEAR
502114,21:45932940:T>C,NM_144991.2:c.1567-3671A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.58,\N,\N,TSPEAR
502115,21:45932948:T>C,NM_144991.2:c.1567-3679A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.509,\N,\N,TSPEAR
502116,21:45932955:A>G,NM_144991.2:c.1567-3686T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.256,\N,\N,TSPEAR
502117,21:45932979:G>T,NM_144991.2:c.1567-3710C>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.641,\N,\N,TSPEAR
502118,21:45933028:C>T,NM_144991.2:c.1567-3759G>A,\N,\N,9/11,Benign,\N,intron_variant,1.52,0.0109,1KG_EUR_AF,TSPEAR
502119,21:45933064:C>T,NM_144991.2:c.1567-3795G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.623,\N,\N,TSPEAR
502120,21:45933065:G>A,NM_144991.2:c.1567-3796C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.596,\N,\N,TSPEAR
502121,21:45933070:G>T,NM_144991.2:c.1567-3801C>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.636,\N,\N,TSPEAR
502122,21:45933072:C>T,NM_144991.2:c.1567-3803G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.19,\N,\N,TSPEAR
502123,21:45933161:C>T,NM_144991.2:c.1567-3892G>A,\N,\N,9/11,Benign,\N,intron_variant,6.407,0.0086,1KG_AMR_AF,TSPEAR
502124,21:45933168:C>T,NM_144991.2:c.1567-3899G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.11,0.0008,1KG_AFR_AF,TSPEAR
502125,21:45933169:G>A,NM_144991.2:c.1567-3900C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.266,\N,\N,TSPEAR
502126,21:45933190:G>A,NM_144991.2:c.1567-3921C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,5.672,\N,\N,TSPEAR
502127,21:45933195:G>C,NM_144991.2:c.1567-3926C>G,\N,\N,9/11,Benign,\N,intron_variant,1.432,0.0287,1KG_AFR_AF,TSPEAR
502128,21:45933202:C>G,NM_144991.2:c.1567-3933G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,3.292,0.001,1KG_EUR_AF,TSPEAR
502129,21:45933224:A>C,NM_144991.2:c.1567-3955T>G,\N,\N,9/11,Unknown significance,\N,intron_variant,1.87,0.0008,1KG_AFR_AF,TSPEAR
502130,21:45933247:AC>A,NM_144991.2:c.1567-3979del,\N,\N,9/11,Benign,\N,intron_variant,2.96,0.1097,1KG_AFR_AF,TSPEAR
502131,21:45933253:CT>C,NM_144991.2:c.1567-3985del,\N,\N,9/11,Benign,\N,intron_variant,1.063,0.0182,1KG_AFR_AF,TSPEAR
502132,21:45933254:T>C,NM_144991.2:c.1567-3985A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.326,\N,\N,TSPEAR
502133,21:45933258:A>C,NM_144991.2:c.1567-3989T>G,\N,\N,9/11,Unknown significance,\N,intron_variant,3.017,\N,\N,TSPEAR
502134,21:45933272:T>G,NM_144991.2:c.1567-4003A>C,\N,\N,9/11,Unknown significance,\N,intron_variant,2.377,0.0008,1KG_AFR_AF,TSPEAR
502135,21:45933300:A>G,NM_144991.2:c.1567-4031T>C,\N,\N,9/11,Benign,\N,intron_variant,3.055,0.0227,1KG_AFR_AF,TSPEAR
502136,21:45933307:A>G,NM_144991.2:c.1567-4038T>C,\N,\N,9/11,Benign,\N,intron_variant,3.33,0.0091,1KG_AFR_AF,TSPEAR
502137,21:45933350:G>A,NM_144991.2:c.1567-4081C>T,\N,\N,9/11,Benign,\N,intron_variant,3.071,0.006,1KG_EAS_AF,TSPEAR
502138,21:45933356:C>T,NM_144991.2:c.1567-4087G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,6.329,\N,\N,TSPEAR
502139,21:45933387:G>A,NM_144991.2:c.1567-4118C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,9.141,\N,\N,TSPEAR
502140,21:45933395:C>T,NM_144991.2:c.1567-4126G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,4.894,0.0014,1KG_AMR_AF,TSPEAR
502141,21:45933396:G>A,NM_144991.2:c.1567-4127C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.179,\N,\N,TSPEAR
502142,21:45933402:C>T,NM_144991.2:c.1567-4133G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,4.983,\N,\N,TSPEAR
502143,21:45933408:A>G,NM_144991.2:c.1567-4139T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,4.235,0.0014,1KG_AMR_AF,TSPEAR
502144,21:45933445:C>T,NM_144991.2:c.1567-4176G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,9.224,0.002,1KG_SAS_AF,TSPEAR
502145,21:45933452:T>C,NM_144991.2:c.1567-4183A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,2.111,0.001,1KG_EUR_AF,TSPEAR
502146,21:45933457:G>C,NM_144991.2:c.1567-4188C>G,\N,\N,9/11,Benign,\N,intron_variant,4.387,0.0143,1KG_SAS_AF,TSPEAR
502147,21:45933460:C>T,NM_144991.2:c.1567-4191G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,8.393,0.004,1KG_EAS_AF,TSPEAR
502148,21:45933473:C>G,NM_144991.2:c.1567-4204G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,3.642,\N,\N,TSPEAR
502149,21:45933475:G>A,NM_144991.2:c.1567-4206C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,4.61,\N,\N,TSPEAR
502150,21:45933492:G>A,NM_144991.2:c.1567-4223C>T,\N,\N,9/11,Benign,\N,intron_variant,4.273,0.0072,1KG_AMR_AF,TSPEAR
502151,21:45933505:CAGG>C,NM_144991.2:c.1567-4239_1567-4237del,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
502152,21:45933514:C>A,NM_144991.2:c.1567-4245G>T,\N,\N,9/11,Unknown significance,\N,intron_variant,11.37,0.0008,1KG_AFR_AF,TSPEAR
502153,21:45933519:GCCC>G,NM_144991.2:c.1567-4253_1567-4251del,\N,\N,9/11,Benign,\N,intron_variant,7.683,0.0061,1KG_SAS_AF,TSPEAR
502154,21:45933527:C>T,NM_144991.2:c.1567-4258G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,6.525,0.001,1KG_EAS_AF,TSPEAR
502155,21:45933542:C>T,NM_144991.2:c.1567-4273G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.747,\N,\N,TSPEAR
502156,21:45933543:G>A,NM_144991.2:c.1567-4274C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,5.321,\N,\N,TSPEAR
502157,21:45933547:G>A,NM_144991.2:c.1567-4278C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,4.826,0.001,1KG_SAS_AF,TSPEAR
502158,21:45933554:C>T,NM_144991.2:c.1567-4285G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,10.29,0.001,1KG_EAS_AF,TSPEAR
502159,21:45933555:G>A,NM_144991.2:c.1567-4286C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,9.758,0.0038,1KG_AFR_AF,TSPEAR
502160,21:45933580:C>A,NM_144991.2:c.1567-4311G>T,\N,\N,9/11,Unknown significance,\N,intron_variant,12.57,\N,\N,TSPEAR
502161,21:45933580:C>T,NM_144991.2:c.1567-4311G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,12.55,0.003,1KG_AFR_AF,TSPEAR
502162,21:45933599:C>T,NM_144991.2:c.1567-4330G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,12.35,0.001,1KG_EAS_AF|1KG_EUR_AF,TSPEAR
502163,21:45933600:G>A,NM_144991.2:c.1567-4331C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,10.93,0.0008,1KG_AFR_AF,TSPEAR
502164,21:45933608:T>C,NM_144991.2:c.1567-4339A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,6.739,0.001,1KG_SAS_AF,TSPEAR
502165,21:45933613:C>G,NM_144991.2:c.1567-4344G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,5.367,\N,\N,TSPEAR
502166,21:45933617:G>T,NM_144991.2:c.1567-4348C>A,\N,\N,9/11,Unknown significance,\N,intron_variant,4.206,0.0008,1KG_AFR_AF,TSPEAR
502167,21:45933620:A>G,NM_144991.2:c.1567-4351T>C,\N,\N,9/11,Benign,\N,intron_variant,0.243,0.0061,1KG_SAS_AF,TSPEAR
502168,21:45933621:G>C,NM_144991.2:c.1567-4352C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.388,0.002,1KG_EUR_AF,TSPEAR
502169,21:45933628:C>G,NM_144991.2:c.1567-4359G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,6.625,0.0008,1KG_AFR_AF,TSPEAR
502170,21:45933644:A>C,NM_144991.2:c.1567-4375T>G,\N,\N,9/11,Benign,\N,intron_variant,0.643,0.0166,1KG_AFR_AF,TSPEAR
502171,21:45933648:CAGGGG>C,NM_144991.2:c.1567-4384_1567-4380del,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
502172,21:45933664:G>T,NM_144991.2:c.1567-4395C>A,\N,\N,9/11,Benign,\N,intron_variant,1.722,0.0083,1KG_AFR_AF,TSPEAR
502173,21:45933680:G>A,NM_144991.2:c.1567-4411C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.868,\N,\N,TSPEAR
502174,21:45933682:G>A,NM_144991.2:c.1567-4413C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,5.901,0.0029,1KG_AMR_AF,TSPEAR
502175,21:45933705:G>A,NM_144991.2:c.1567-4436C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,4.374,\N,\N,TSPEAR
502176,21:45933729:T>TG,NM_144991.2:c.1567-4461dup,\N,\N,9/11,Benign,\N,intron_variant,1.818,0.0197,1KG_AFR_AF,TSPEAR
502177,21:45933731:G>C,NM_144991.2:c.1567-4462C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.954,\N,\N,TSPEAR
502178,21:45933752:T>C,NM_144991.2:c.1567-4483A>G,\N,\N,9/11,Benign,\N,intron_variant,0.275,0.4145,1KG_AFR_AF,TSPEAR
502179,21:45933753:G>A,NM_144991.2:c.1567-4484C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.841,\N,\N,TSPEAR
502180,21:45933785:C>T,NM_144991.2:c.1567-4516G>A,\N,\N,9/11,Benign,\N,intron_variant,0.059,0.0486,1KG_EAS_AF,TSPEAR
502181,21:45933786:G>A,NM_144991.2:c.1567-4517C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.881,0.001,1KG_SAS_AF,TSPEAR
502182,21:45933800:G>A,NM_144991.2:c.1567-4531C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,2.745,0.001,1KG_EUR_AF,TSPEAR
502183,21:45933803:G>A,NM_144991.2:c.1567-4534C>T,\N,\N,9/11,Benign,\N,intron_variant,0.131,0.0083,1KG_AFR_AF,TSPEAR
502184,21:45933805:G>A,NM_144991.2:c.1567-4536C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.269,0.0015,1KG_AFR_AF,TSPEAR
502185,21:45933805:G>T,NM_144991.2:c.1567-4536C>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.089,\N,\N,TSPEAR
502186,21:45933823:A>C,NM_144991.2:c.1567-4554T>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.124,\N,\N,TSPEAR
502187,21:45933853:T>TC,NM_144991.2:c.1567-4585dup,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
502188,21:45933856:C>T,NM_144991.2:c.1567-4587G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,7.754,\N,\N,TSPEAR
502189,21:45933860:C>G,NM_144991.2:c.1567-4591G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,3.868,\N,\N,TSPEAR
502190,21:45933874:C>T,NM_144991.2:c.1567-4605G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.414,\N,\N,TSPEAR
502191,21:45933876:C>T,NM_144991.2:c.1567-4607G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,5.086,0.001,1KG_EAS_AF,TSPEAR
502192,21:45933879:C>T,NM_144991.2:c.1567-4610G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,4.352,0.0014,1KG_AMR_AF,TSPEAR
502193,21:45933880:G>A,NM_144991.2:c.1567-4611C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.735,\N,\N,TSPEAR
502194,21:45933891:G>A,NM_144991.2:c.1567-4622C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.271,0.001,1KG_EAS_AF|1KG_SAS_AF,TSPEAR
502195,21:45933895:C>T,NM_144991.2:c.1567-4626G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,4.494,\N,\N,TSPEAR
502196,21:45933905:C>T,NM_144991.2:c.1567-4636G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.815,0.0008,1KG_AFR_AF,TSPEAR
502197,21:45933906:G>A,NM_144991.2:c.1567-4637C>T,\N,\N,9/11,Benign,\N,intron_variant,0.978,0.0121,1KG_AFR_AF,TSPEAR
502198,21:45933957:C>T,NM_144991.2:c.1567-4688G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,4.848,0.0038,1KG_AFR_AF,TSPEAR
502199,21:45933961:G>A,NM_144991.2:c.1567-4692C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.803,\N,\N,TSPEAR
502200,21:45933966:C>T,NM_144991.2:c.1567-4697G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,4.038,0.0038,1KG_AFR_AF,TSPEAR
502201,21:45933973:C>T,NM_144991.2:c.1567-4704G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.435,0.0008,1KG_AFR_AF,TSPEAR
502202,21:45933996:C>T,NM_144991.2:c.1567-4727G>A,\N,\N,9/11,Benign,\N,intron_variant,2.818,0.0219,1KG_AFR_AF,TSPEAR
502203,21:45934000:A>C,NM_144991.2:c.1567-4731T>G,\N,\N,9/11,Unknown significance,\N,intron_variant,1.022,\N,\N,TSPEAR
502204,21:45934008:C>T,NM_144991.2:c.1567-4739G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.822,0.002,1KG_SAS_AF,TSPEAR
502205,21:45934015:G>A,NM_144991.2:c.1567-4746C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,5.13,0.0008,1KG_AFR_AF,TSPEAR
502206,21:45934056:C>T,NM_144991.2:c.1567-4787G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.755,0.001,1KG_EUR_AF,TSPEAR
502207,21:45934068:C>T,NM_144991.2:c.1567-4799G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.369,0.001,1KG_EAS_AF,TSPEAR
502208,21:45934074:G>A,NM_144991.2:c.1567-4805C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.123,0.001,1KG_EAS_AF,TSPEAR
502209,21:45934084:C>T,NM_144991.2:c.1567-4815G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.621,\N,\N,TSPEAR
502210,21:45934118:G>A,NM_144991.2:c.1567-4849C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.109,\N,\N,TSPEAR
502211,21:45934119:G>A,NM_144991.2:c.1567-4850C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.962,\N,\N,TSPEAR
502212,21:45934166:T>G,NM_144991.2:c.1567-4897A>C,\N,\N,9/11,Unknown significance,\N,intron_variant,6.142,\N,\N,TSPEAR
502213,21:45934169:C>T,NM_144991.2:c.1567-4900G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,4.733,0.0008,1KG_AFR_AF,TSPEAR
502214,21:45934170:G>A,NM_144991.2:c.1567-4901C>T,\N,\N,9/11,Benign,\N,intron_variant,0.414,0.0061,1KG_SAS_AF,TSPEAR
502215,21:45934180:C>G,NM_144991.2:c.1567-4911G>C,\N,\N,9/11,Benign,\N,intron_variant,0.621,0.006,1KG_EUR_AF,TSPEAR
502216,21:45934195:C>T,NM_144991.2:c.1567-4926G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.414,0.0015,1KG_AFR_AF,TSPEAR
502217,21:45934197:C>T,NM_144991.2:c.1567-4928G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.512,0.0008,1KG_AFR_AF,TSPEAR
502218,21:45934200:T>C,NM_144991.2:c.1567-4931A>G,\N,\N,9/11,Benign,\N,intron_variant,0.391,0.9932,1KG_AFR_AF,TSPEAR
502219,21:45934234:G>T,NM_144991.2:c.1567-4965C>A,\N,\N,9/11,Benign,\N,intron_variant,0.051,0.006,1KG_EUR_AF,TSPEAR
502220,21:45934236:C>T,NM_144991.2:c.1567-4967G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,4.542,\N,\N,TSPEAR
502221,21:45934244:C>T,NM_144991.2:c.1567-4975G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.41,0.001,1KG_EAS_AF,TSPEAR
502222,21:45934256:CGTGTGCATGA>C,NM_144991.2:c.1567-4997_1567-4988del,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
502223,21:45934266:AGTGTGCATGT>A,NM_144991.2:c.1567-5007_1567-4998del,\N,\N,9/11,Benign,\N,intron_variant,3.345,0.0189,1KG_AFR_AF,TSPEAR
502224,21:45934272:C>T,NM_144991.2:c.1567-5003G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.381,0.001,1KG_SAS_AF,TSPEAR
502225,21:45934273:A>G,NM_144991.2:c.1567-5004T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,1.751,\N,\N,TSPEAR
502226,21:45934276:T>A,NM_144991.2:c.1567-5007A>T,\N,\N,9/11,Unknown significance,\N,intron_variant,5.159,\N,\N,TSPEAR
502227,21:45934276:T>C,NM_144991.2:c.1567-5007A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,2.772,0.001,1KG_SAS_AF,TSPEAR
502228,21:45934298:C>T,NM_144991.2:c.1567-5029G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.495,\N,\N,TSPEAR
502229,21:45934299:G>A,NM_144991.2:c.1567-5030C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,2.275,\N,\N,TSPEAR
502230,21:45934301:G>A,NM_144991.2:c.1567-5032C>T,\N,\N,9/11,Benign,\N,intron_variant,2.878,0.0204,1KG_AFR_AF,TSPEAR
502231,21:45934326:A>C,NM_144991.2:c.1567-5057T>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.1,\N,\N,TSPEAR
502232,21:45934385:G>C,NM_144991.2:c.1567-5116C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,1.237,0.001,1KG_SAS_AF,TSPEAR
502233,21:45934401:C>G,NM_144991.2:c.1567-5132G>C,\N,\N,9/11,Benign,\N,intron_variant,3.283,0.0113,1KG_AFR_AF,TSPEAR
502234,21:45934402:C>T,NM_144991.2:c.1567-5133G>A,\N,\N,9/11,Benign,\N,intron_variant,2.382,0.007,1KG_EUR_AF,TSPEAR
502235,21:45934403:G>A,NM_144991.2:c.1567-5134C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.367,\N,\N,TSPEAR
502236,21:45934410:G>C,NM_144991.2:c.1567-5141C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.017,\N,\N,TSPEAR
502237,21:45934413:A>G,NM_144991.2:c.1567-5144T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,1.322,0.001,1KG_EUR_AF,TSPEAR
502238,21:45934425:C>T,NM_144991.2:c.1567-5156G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.297,\N,\N,TSPEAR
502239,21:45934429:G>C,NM_144991.2:c.1567-5160C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.677,\N,\N,TSPEAR
502240,21:45934434:G>A,NM_144991.2:c.1567-5165C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.838,0.0045,1KG_AFR_AF,TSPEAR
502241,21:45934447:C>T,NM_144991.2:c.1567-5178G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.624,\N,\N,TSPEAR
502242,21:45934447:CCTTCTGAGGTCTGCAGCAA>C,NM_144991.2:c.1567-5197_1567-5179del,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,0.0014,1KG_AMR_AF,TSPEAR
502243,21:45934455:G>A,NM_144991.2:c.1567-5186C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.452,\N,\N,TSPEAR
502244,21:45934471:A>C,NM_144991.2:c.1567-5202T>G,\N,\N,9/11,Unknown significance,\N,intron_variant,3.456,0.001,1KG_EUR_AF,TSPEAR
502245,21:45934488:ATT>A,NM_144991.2:c.1567-5221_1567-5220del,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
502246,21:45934492:T>C,NM_144991.2:c.1567-5223A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.541,0.001,1KG_SAS_AF,TSPEAR
502247,21:45934497:T>C,NM_144991.2:c.1567-5228A>G,\N,\N,9/11,Benign,\N,intron_variant,0.093,0.0318,1KG_AFR_AF,TSPEAR
502248,21:45934512:C>T,NM_144991.2:c.1567-5243G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.361,0.001,1KG_EAS_AF,TSPEAR
502249,21:45934514:C>T,NM_144991.2:c.1567-5245G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.675,\N,\N,TSPEAR
502250,21:45934522:C>G,NM_144991.2:c.1567-5253G>C,\N,\N,9/11,Benign,\N,intron_variant,1.099,0.2095,1KG_AFR_AF,TSPEAR
502251,21:45934522:C>T,NM_144991.2:c.1567-5253G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.107,\N,\N,TSPEAR
502252,21:45934523:G>A,NM_144991.2:c.1567-5254C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.706,0.0045,1KG_AFR_AF,TSPEAR
502253,21:45934534:C>T,NM_144991.2:c.1567-5265G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.396,0.0023,1KG_AFR_AF,TSPEAR
502254,21:45934564:A>C,NM_144991.2:c.1567-5295T>G,\N,\N,9/11,Benign,\N,intron_variant,0.768,0.0825,1KG_AFR_AF,TSPEAR
502255,21:45934570:C>T,NM_144991.2:c.1567-5301G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,5.458,\N,\N,TSPEAR
502256,21:45934575:G>A,NM_144991.2:c.1567-5306C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.882,0.0008,1KG_AFR_AF,TSPEAR
502257,21:45934597:G>T,NM_144991.2:c.1567-5328C>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.566,0.001,1KG_SAS_AF,TSPEAR
502258,21:45934606:G>A,NM_144991.2:c.1567-5337C>T,\N,\N,9/11,Benign,\N,intron_variant,5.092,0.0091,1KG_AFR_AF,TSPEAR
502259,21:45934619:C>T,NM_144991.2:c.1567-5350G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.305,\N,\N,TSPEAR
502260,21:45934620:A>C,NM_144991.2:c.1567-5351T>G,\N,\N,9/11,Unknown significance,\N,intron_variant,1.194,\N,\N,TSPEAR
502261,21:45934621:T>C,NM_144991.2:c.1567-5352A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.495,\N,\N,TSPEAR
502262,21:45934658:TCTAGAATTC>T,NM_144991.2:c.1567-5398_1567-5390del,\N,\N,9/11,Unknown significance,\N,intron_variant,11.6,\N,\N,TSPEAR
502263,21:45934679:G>A,NM_144991.2:c.1567-5410C>T,\N,\N,9/11,Benign,\N,intron_variant,2.285,0.0802,1KG_AFR_AF,TSPEAR
502264,21:45934689:C>CT,NM_144991.2:c.1567-5421dup,\N,\N,9/11,Benign,\N,intron_variant,6.909,0.0202,1KG_AMR_AF,TSPEAR
502265,21:45934691:T>C,NM_144991.2:c.1567-5422A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,2.81,0.0008,1KG_AFR_AF,TSPEAR
502266,21:45934703:G>A,NM_144991.2:c.1567-5434C>T,\N,\N,9/11,Benign,\N,intron_variant,1.08,0.0337,1KG_EAS_AF,TSPEAR
502267,21:45934708:A>G,NM_144991.2:c.1567-5439T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,1.761,0.001,1KG_SAS_AF,TSPEAR
502268,21:45934719:A>C,NM_144991.2:c.1567-5450T>G,\N,\N,9/11,Benign,\N,intron_variant,0.448,0.0053,1KG_AFR_AF,TSPEAR
502269,21:45934736:G>C,NM_144991.2:c.1567-5467C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.314,0.0008,1KG_AFR_AF,TSPEAR
502270,21:45934738:G>A,NM_144991.2:c.1567-5469C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.198,\N,\N,TSPEAR
502271,21:45934757:C>T,NM_144991.2:c.1567-5488G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,4.509,\N,\N,TSPEAR
502272,21:45934776:C>T,NM_144991.2:c.1567-5507G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.156,0.003,1KG_AFR_AF,TSPEAR
502273,21:45934796:C>T,NM_144991.2:c.1567-5527G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.632,0.0014,1KG_AMR_AF,TSPEAR
502274,21:45934837:T>G,NM_144991.2:c.1567-5568A>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.495,\N,\N,TSPEAR
502275,21:45934842:A>C,NM_144991.2:c.1567-5573T>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.683,\N,\N,TSPEAR
502276,21:45934845:C>T,NM_144991.2:c.1567-5576G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.196,0.002,1KG_EAS_AF,TSPEAR
502277,21:45934850:A>AC,NM_144991.2:c.1567-5582dup,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
502278,21:45934870:A>G,NM_144991.2:c.1567-5601T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.769,\N,\N,TSPEAR
502279,21:45934873:G>A,NM_144991.2:c.1567-5604C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.69,\N,\N,TSPEAR
502280,21:45934881:TGTGC>T,NM_144991.2:c.1567-5616_1567-5613del,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
502281,21:45934908:C>T,NM_144991.2:c.1567-5639G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.097,\N,\N,TSPEAR
502282,21:45934913:C>T,NM_144991.2:c.1567-5644G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,5.878,0.0023,1KG_AFR_AF,TSPEAR
502283,21:45934919:C>T,NM_144991.2:c.1567-5650G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,8.572,\N,\N,TSPEAR
502284,21:45934922:G>A,NM_144991.2:c.1567-5653C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.677,\N,\N,TSPEAR
502285,21:45934923:C>A,NM_144991.2:c.1567-5654G>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.839,0.0045,1KG_AFR_AF,TSPEAR
502286,21:45934926:A>G,NM_144991.2:c.1567-5657T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,4.199,\N,\N,TSPEAR
502287,21:45934928:C>A,NM_144991.2:c.1567-5659G>T,\N,\N,9/11,Unknown significance,\N,intron_variant,8.025,0.0014,1KG_AMR_AF,TSPEAR
502288,21:45934943:G>A,NM_144991.2:c.1567-5674C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,2.473,0.0045,1KG_AFR_AF,TSPEAR
502289,21:45934945:C>CT,NM_144991.2:c.1567-5677dup,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
502290,21:45934952:T>G,NM_144991.2:c.1567-5683A>C,\N,\N,9/11,Benign,\N,intron_variant,4.173,0.0429,1KG_SAS_AF,TSPEAR
502291,21:45934961:C>T,NM_144991.2:c.1567-5692G>A,\N,\N,9/11,Benign,\N,intron_variant,3.098,0.0174,1KG_AFR_AF,TSPEAR
502292,21:45934962:C>G,NM_144991.2:c.1567-5693G>C,\N,\N,9/11,Benign,\N,intron_variant,0.585,0.121,1KG_AFR_AF,TSPEAR
502293,21:45934980:G>A,NM_144991.2:c.1567-5711C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.29,\N,\N,TSPEAR
502294,21:45934990:G>A,NM_144991.2:c.1567-5721C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,14.09,\N,\N,TSPEAR
502295,21:45935004:G>A,NM_144991.2:c.1567-5735C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,8.96,\N,\N,TSPEAR
502296,21:45935014:G>C,NM_144991.2:c.1567-5745C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,12.57,0.001,1KG_EAS_AF,TSPEAR
502297,21:45935027:TCAAA>T,NM_144991.2:c.1567-5762_1567-5759del,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
502298,21:45935027:TCAAAC>T,NM_144991.2:c.1567-5763_1567-5759del,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
502299,21:45935038:A>G,NM_144991.2:c.1567-5769T>C,\N,\N,9/11,Benign,\N,intron_variant,15.17,0.006,1KG_EAS_AF,TSPEAR
502300,21:45935044:CAAATT>C,NM_144991.2:c.1567-5780_1567-5776del,\N,\N,9/11,Unknown significance,\N,intron_variant,18.9,0.0038,1KG_AFR_AF,TSPEAR
502301,21:45935064:A>C,NM_144991.2:c.1567-5795T>G,\N,\N,9/11,Unknown significance,\N,intron_variant,10.09,\N,\N,TSPEAR
502302,21:45935067:T>C,NM_144991.2:c.1567-5798A>G,\N,\N,9/11,Benign,\N,intron_variant,14.06,0.0079,1KG_EAS_AF,TSPEAR
502303,21:45935091:G>A,NM_144991.2:c.1567-5822C>T,\N,\N,9/11,Benign,\N,intron_variant,9.796,0.1278,1KG_AFR_AF,TSPEAR
502304,21:45935094:A>G,NM_144991.2:c.1567-5825T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,10.43,0.0008,1KG_AFR_AF,TSPEAR
502305,21:45935107:A>G,NM_144991.2:c.1567-5838T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,21.8,\N,\N,TSPEAR
502306,21:45935109:GA>G,NM_144991.2:c.1567-5841del,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
502307,21:45935117:G>C,NM_144991.2:c.1567-5848C>G,\N,\N,9/11,Benign,\N,intron_variant,13.08,0.0174,1KG_AFR_AF,TSPEAR
502308,21:45935118:C>T,NM_144991.2:c.1567-5849G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,16.1,0.0031,1KG_SAS_AF,TSPEAR
502309,21:45935125:A>C,NM_144991.2:c.1567-5856T>G,\N,\N,9/11,Unknown significance,\N,intron_variant,13.2,0.0008,1KG_AFR_AF,TSPEAR
502310,21:45935143:A>G,NM_144991.2:c.1567-5874T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,6.833,\N,\N,TSPEAR
502311,21:45935159:G>A,NM_144991.2:c.1567-5890C>T,\N,\N,9/11,Benign,\N,intron_variant,1.849,0.0129,1KG_EAS_AF,TSPEAR
502312,21:45935175:G>C,NM_144991.2:c.1567-5906C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.846,\N,\N,TSPEAR
502313,21:45935196:C>T,NM_144991.2:c.1567-5927G>A,\N,\N,9/11,Benign,\N,intron_variant,3.425,0.0199,1KG_EUR_AF,TSPEAR
502314,21:45935197:G>A,NM_144991.2:c.1567-5928C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.584,0.002,1KG_EUR_AF,TSPEAR
502315,21:45935207:C>T,NM_144991.2:c.1567-5938G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,5.017,0.001,1KG_EAS_AF,TSPEAR
502316,21:45935218:G>A,NM_144991.2:c.1567-5949C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,5.254,0.0023,1KG_AFR_AF,TSPEAR
502317,21:45935244:T>C,NM_144991.2:c.1567-5975A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,2.629,\N,\N,TSPEAR
502318,21:45935252:G>A,NM_144991.2:c.1567-5983C>T,\N,\N,9/11,Benign,\N,intron_variant,4.336,0.0673,1KG_AFR_AF,TSPEAR
502319,21:45935257:C>T,NM_144991.2:c.1567-5988G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.117,0.002,1KG_EAS_AF,TSPEAR
502320,21:45935258:G>A,NM_144991.2:c.1567-5989C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.824,0.001,1KG_EUR_AF,TSPEAR
502321,21:45935264:A>C,NM_144991.2:c.1567-5995T>G,\N,\N,9/11,Unknown significance,\N,intron_variant,1.455,0.002,1KG_EUR_AF,TSPEAR
502322,21:45935279:G>A,NM_144991.2:c.1567-6010C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.015,\N,\N,TSPEAR
502323,21:45935285:G>A,NM_144991.2:c.1567-6016C>T,\N,\N,9/11,Benign,\N,intron_variant,1.671,0.008,1KG_EUR_AF,TSPEAR
502324,21:45935316:C>T,NM_144991.2:c.1567-6047G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.123,0.0008,1KG_AFR_AF,TSPEAR
502325,21:45935317:G>A,NM_144991.2:c.1567-6048C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,2.765,0.001,1KG_SAS_AF,TSPEAR
502326,21:45935328:T>C,NM_144991.2:c.1567-6059A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,2.151,0.0014,1KG_AMR_AF,TSPEAR
502327,21:45935361:TCTC>T,NM_144991.2:c.1567-6095_1567-6093del,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
502328,21:45935364:CTGA>C,NM_144991.2:c.1567-6098_1567-6096del,\N,\N,9/11,Unknown significance,\N,intron_variant,1.541,\N,\N,TSPEAR
502329,21:45935381:C>T,NR_103707.1:n.1476C>T,\N,7/7,\N,Unknown significance,\N,splice_region_variant&non_coding_transcript_exon_variant,1.645,0.0014,1KG_AMR_AF,TSPEAR
502330,21:45935382:G>A,NR_103707.1:n.1477G>A,\N,7/7,\N,Unknown significance,\N,splice_region_variant&non_coding_transcript_exon_variant,0.112,\N,\N,TSPEAR
502331,21:45935407:C>T,NM_144991.2:c.1567-6138G>A,\N,\N,9/11,Benign,\N,intron_variant,6.602,0.0159,1KG_AFR_AF,TSPEAR
502332,21:45935408:G>A,NM_144991.2:c.1567-6139C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,2.988,\N,\N,TSPEAR
502333,21:45935417:C>T,NM_144991.2:c.1567-6148G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,6.538,\N,\N,TSPEAR
502334,21:45935436:CTTGGTTCCG>C,NM_144991.2:c.1567-6176_1567-6168del,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
502335,21:45935444:C>T,NM_144991.2:c.1567-6175G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.561,\N,\N,TSPEAR
502336,21:45935445:G>A,NM_144991.2:c.1567-6176C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,6.47,0.002,1KG_EUR_AF,TSPEAR
502337,21:45935494:C>T,NM_144991.2:c.1567-6225G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,4.007,\N,\N,TSPEAR
502338,21:45935495:G>A,NM_144991.2:c.1567-6226C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.381,\N,\N,TSPEAR
502339,21:45935517:C>G,NM_144991.2:c.1567-6248G>C,\N,\N,9/11,Benign,\N,intron_variant,2.408,0.0734,1KG_AFR_AF,TSPEAR
502340,21:45935532:G>A,NM_144991.2:c.1566+6234C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.166,0.001,1KG_EAS_AF,TSPEAR
502341,21:45935550:C>A,NM_144991.2:c.1566+6216G>T,\N,\N,9/11,Unknown significance,\N,intron_variant,6.371,0.0008,1KG_AFR_AF,TSPEAR
502342,21:45935552:C>T,NM_144991.2:c.1566+6214G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,7.761,\N,\N,TSPEAR
502343,21:45935553:G>A,NM_144991.2:c.1566+6213C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,6.346,0.001,1KG_EUR_AF,TSPEAR
502344,21:45935555:G>A,NM_144991.2:c.1566+6211C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.358,0.0041,1KG_SAS_AF,TSPEAR
502345,21:45935577:G>A,NM_144991.2:c.1566+6189C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.751,0.0008,1KG_AFR_AF,TSPEAR
502346,21:45935589:G>A,NM_144991.2:c.1566+6177C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,2.122,\N,\N,TSPEAR
502347,21:45935603:A>C,NM_144991.2:c.1566+6163T>G,\N,\N,9/11,Unknown significance,\N,intron_variant,5.398,0.001,1KG_EAS_AF,TSPEAR
502348,21:45935605:C>T,NM_144991.2:c.1566+6161G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,6.127,\N,\N,TSPEAR
502349,21:45935608:A>C,NM_144991.2:c.1566+6158T>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.026,0.0008,1KG_AFR_AF,TSPEAR
502350,21:45935614:C>T,NM_144991.2:c.1566+6152G>A,\N,\N,9/11,Benign,\N,intron_variant,7.703,0.1278,1KG_AFR_AF,TSPEAR
502351,21:45935629:G>T,NM_144991.2:c.1566+6137C>A,\N,\N,9/11,Unknown significance,\N,intron_variant,5.027,0.001,1KG_EAS_AF,TSPEAR
502352,21:45935636:T>C,NM_144991.2:c.1566+6130A>G,\N,\N,9/11,Benign,\N,intron_variant,0.333,0.0363,1KG_AFR_AF,TSPEAR
502353,21:45935647:G>A,NM_144991.2:c.1566+6119C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,4.519,\N,\N,TSPEAR
502354,21:45935664:C>T,NM_144991.2:c.1566+6102G>A,\N,\N,9/11,Benign,\N,intron_variant,1.948,0.0371,1KG_AFR_AF,TSPEAR
502355,21:45935665:G>A,NM_144991.2:c.1566+6101C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,6.658,0.0008,1KG_AFR_AF,TSPEAR
502356,21:45935689:A>C,NM_144991.2:c.1566+6077T>G,\N,\N,9/11,Unknown significance,\N,intron_variant,1.641,\N,\N,TSPEAR
502357,21:45935702:A>G,NM_144991.2:c.1566+6064T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,4.597,0.0031,1KG_SAS_AF,TSPEAR
502358,21:45935714:C>T,NM_144991.2:c.1566+6052G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.44,0.0014,1KG_AMR_AF,TSPEAR
502359,21:45935718:G>A,NM_144991.2:c.1566+6048C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,4.24,0.0008,1KG_AFR_AF,TSPEAR
502360,21:45935733:G>A,NM_144991.2:c.1566+6033C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,6.095,0.0008,1KG_AFR_AF,TSPEAR
502361,21:45935762:A>G,NM_144991.2:c.1566+6004T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,4.913,0.0008,1KG_AFR_AF,TSPEAR
502362,21:45935798:C>A,NM_144991.2:c.1566+5968G>T,\N,\N,9/11,Unknown significance,\N,intron_variant,2.56,0.0014,1KG_AMR_AF,TSPEAR
502363,21:45935799:G>A,NM_144991.2:c.1566+5967C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.517,\N,\N,TSPEAR
502364,21:45935818:C>T,NM_144991.2:c.1566+5948G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.825,\N,\N,TSPEAR
502365,21:45935843:A>G,NM_144991.2:c.1566+5923T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,3.859,0.002,1KG_EUR_AF,TSPEAR
502366,21:45935869:G>A,NM_144991.2:c.1566+5897C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.901,\N,\N,TSPEAR
502367,21:45935907:G>A,NM_144991.2:c.1566+5859C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,4.655,\N,\N,TSPEAR
502368,21:45935917:C>T,NM_144991.2:c.1566+5849G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.6,\N,\N,TSPEAR
502369,21:45935922:C>T,NM_144991.2:c.1566+5844G>A,\N,\N,9/11,Benign,\N,intron_variant,0.181,0.0356,1KG_AFR_AF,TSPEAR
502370,21:45935923:G>A,NM_144991.2:c.1566+5843C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.488,\N,\N,TSPEAR
502371,21:45935926:G>A,NM_144991.2:c.1566+5840C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.219,\N,\N,TSPEAR
502372,21:45935942:G>C,NM_144991.2:c.1566+5824C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.456,\N,\N,TSPEAR
502373,21:45935943:T>G,NM_144991.2:c.1566+5823A>C,\N,\N,9/11,Unknown significance,\N,intron_variant,4.672,0.001,1KG_SAS_AF,TSPEAR
502374,21:45935944:C>T,NM_144991.2:c.1566+5822G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,6.178,0.0008,1KG_AFR_AF,TSPEAR
502375,21:45935953:T>C,NM_144991.2:c.1566+5813A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,3.593,0.0041,1KG_SAS_AF,TSPEAR
502376,21:45935981:G>A,NM_144991.2:c.1566+5785C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,4.81,\N,\N,TSPEAR
502377,21:45935997:C>T,NM_144991.2:c.1566+5769G>A,\N,\N,9/11,Benign,\N,intron_variant,0.67,0.0051,1KG_SAS_AF,TSPEAR
502378,21:45936016:C>T,NM_144991.2:c.1566+5750G>A,\N,\N,9/11,Benign,\N,intron_variant,1.424,0.0151,1KG_AFR_AF,TSPEAR
502379,21:45936017:G>A,NM_144991.2:c.1566+5749C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.405,\N,\N,TSPEAR
502380,21:45936018:C>G,NM_144991.2:c.1566+5748G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,1.706,0.0038,1KG_AFR_AF,TSPEAR
502381,21:45936026:G>A,NM_144991.2:c.1566+5740C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.389,\N,\N,TSPEAR
502382,21:45936051:G>A,NM_144991.2:c.1566+5715C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,5.539,0.001,1KG_SAS_AF,TSPEAR
502383,21:45936052:G>A,NM_144991.2:c.1566+5714C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,5.394,\N,\N,TSPEAR
502384,21:45936053:C>T,NM_144991.2:c.1566+5713G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.152,0.0014,1KG_AMR_AF,TSPEAR
502385,21:45936082:G>A,NM_144991.2:c.1566+5684C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,2.952,0.0008,1KG_AFR_AF,TSPEAR
502386,21:45936089:G>C,NM_144991.2:c.1566+5677C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,1.155,\N,\N,TSPEAR
502387,21:45936093:G>A,NM_144991.2:c.1566+5673C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.939,\N,\N,TSPEAR
502388,21:45936142:C>T,NM_144991.2:c.1566+5624G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.507,0.003,1KG_AFR_AF,TSPEAR
502389,21:45936179:T>C,NM_144991.2:c.1566+5587A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,3.493,0.002,1KG_SAS_AF,TSPEAR
502390,21:45936195:C>A,NM_144991.2:c.1566+5571G>T,\N,\N,9/11,Benign,\N,intron_variant,3.729,0.0179,1KG_EUR_AF,TSPEAR
502391,21:45936208:C>A,NM_144991.2:c.1566+5558G>T,\N,\N,9/11,Unknown significance,\N,intron_variant,7.14,0.0045,1KG_AFR_AF,TSPEAR
502392,21:45936208:C>T,NM_144991.2:c.1566+5558G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,7.373,\N,\N,TSPEAR
502393,21:45936209:TGCACCTGGTCTGG>T,NM_144991.2:c.1566+5544_1566+5556del,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,0.004,1KG_EAS_AF,TSPEAR
502394,21:45936210:G>C,NM_144991.2:c.1566+5556C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,3.313,0.001,1KG_EUR_AF,TSPEAR
502395,21:45936228:T>C,NM_144991.2:c.1566+5538A>G,\N,\N,9/11,Benign,\N,intron_variant,0.827,0.1172,1KG_AFR_AF,TSPEAR
502396,21:45936240:T>C,NM_144991.2:c.1566+5526A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,3.932,0.0023,1KG_AFR_AF,TSPEAR
502397,21:45936244:C>G,NM_144991.2:c.1566+5522G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,1.671,\N,\N,TSPEAR
502398,21:45936248:CTT>C,NM_144991.2:c.1566+5516_1566+5517del,\N,\N,9/11,Unknown significance,\N,intron_variant,2.84,0.0038,1KG_AFR_AF,TSPEAR
502399,21:45936249:TTAG>AC,NM_144991.2:c.1566+5514_1566+5517delinsGT,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
502400,21:45936252:G>C,NM_144991.2:c.1566+5514C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,2.094,0.0045,1KG_AFR_AF,TSPEAR
502401,21:45936255:T>G,NM_144991.2:c.1566+5511A>C,\N,\N,9/11,Unknown significance,\N,intron_variant,2.841,0.001,1KG_EAS_AF,TSPEAR
502402,21:45936265:C>G,NM_144991.2:c.1566+5501G>C,\N,\N,9/11,Benign,\N,intron_variant,2.672,0.1097,1KG_AFR_AF,TSPEAR
502403,21:45936286:G>T,NM_144991.2:c.1566+5480C>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.348,\N,\N,TSPEAR
502404,21:45936295:T>C,NM_144991.2:c.1566+5471A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,2.689,0.001,1KG_EUR_AF,TSPEAR
502405,21:45936296:C>T,NM_144991.2:c.1566+5470G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.825,\N,\N,TSPEAR
502406,21:45936314:C>T,NM_144991.2:c.1566+5452G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.043,\N,\N,TSPEAR
502407,21:45936315:G>A,NM_144991.2:c.1566+5451C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.868,\N,\N,TSPEAR
502408,21:45936328:G>A,NM_144991.2:c.1566+5438C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.557,0.0045,1KG_AFR_AF,TSPEAR
502409,21:45936338:C>G,NM_144991.2:c.1566+5428G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,1.917,0.001,1KG_EUR_AF,TSPEAR
502410,21:45936340:A>C,NM_144991.2:c.1566+5426T>G,\N,\N,9/11,Benign,\N,intron_variant,0.871,0.0061,1KG_SAS_AF,TSPEAR
502411,21:45936341:C>T,NM_144991.2:c.1566+5425G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.845,0.0014,1KG_AMR_AF,TSPEAR
502412,21:45936342:G>A,NM_144991.2:c.1566+5424C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.948,0.002,1KG_SAS_AF,TSPEAR
502413,21:45936345:G>A,NM_144991.2:c.1566+5421C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.153,\N,\N,TSPEAR
502414,21:45936362:G>C,NM_144991.2:c.1566+5404C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.04,\N,\N,TSPEAR
502415,21:45936376:G>A,NM_144991.2:c.1566+5390C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.834,0.001,1KG_SAS_AF,TSPEAR
502416,21:45936381:CCTT>C,NM_144991.2:c.1566+5382_1566+5384del,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
502417,21:45936384:T>C,NM_144991.2:c.1566+5382A>G,\N,\N,9/11,Benign,\N,intron_variant,2.2,0.0072,1KG_SAS_AF,TSPEAR
502418,21:45936389:C>T,NM_144991.2:c.1566+5377G>A,\N,\N,9/11,Benign,\N,intron_variant,4.573,0.1089,1KG_AFR_AF,TSPEAR
502419,21:45936398:A>G,NM_144991.2:c.1566+5368T>C,\N,\N,9/11,Benign,\N,intron_variant,0.934,0.028,1KG_AFR_AF,TSPEAR
502420,21:45936427:A>G,NM_144991.2:c.1566+5339T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,3.417,0.001,1KG_SAS_AF,TSPEAR
502421,21:45936431:C>A,NM_144991.2:c.1566+5335G>T,\N,\N,9/11,Unknown significance,\N,intron_variant,6.142,\N,\N,TSPEAR
502422,21:45936433:A>C,NM_144991.2:c.1566+5333T>G,\N,\N,9/11,Benign,\N,intron_variant,1.243,0.007,1KG_EUR_AF,TSPEAR
502423,21:45936441:G>A,NM_144991.2:c.1566+5325C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.117,\N,\N,TSPEAR
502424,21:45936455:C>T,NM_144991.2:c.1566+5311G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.188,0.0008,1KG_AFR_AF,TSPEAR
502425,21:45936461:CG>C,NM_144991.2:c.1566+5304del,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
502426,21:45936466:C>T,NM_144991.2:c.1566+5300G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,4.569,\N,\N,TSPEAR
502427,21:45936483:C>T,NM_144991.2:c.1566+5283G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,4.482,0.0008,1KG_AFR_AF,TSPEAR
502428,21:45936498:C>G,NM_144991.2:c.1566+5268G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.778,0.001,1KG_SAS_AF,TSPEAR
502429,21:45936499:G>A,NM_144991.2:c.1566+5267C>T,\N,\N,9/11,Benign,\N,intron_variant,1.051,0.0136,1KG_AFR_AF,TSPEAR
502430,21:45936499:G>C,NM_144991.2:c.1566+5267C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.229,\N,\N,TSPEAR
502431,21:45936500:T>C,NM_144991.2:c.1566+5266A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.805,\N,\N,TSPEAR
502432,21:45936516:C>T,NM_144991.2:c.1566+5250G>A,\N,\N,9/11,Benign,\N,intron_variant,2.084,0.1089,1KG_AFR_AF,TSPEAR
502433,21:45936517:G>A,NM_144991.2:c.1566+5249C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.963,\N,\N,TSPEAR
502434,21:45936530:C>A,NM_144991.2:c.1566+5236G>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.368,0.001,1KG_EAS_AF,TSPEAR
502435,21:45936531:C>T,NM_144991.2:c.1566+5235G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.768,0.001,1KG_EUR_AF,TSPEAR
502436,21:45936540:G>A,NM_144991.2:c.1566+5226C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,12.08,\N,\N,TSPEAR
502437,21:45936546:G>A,NM_144991.2:c.1566+5220C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,9.543,0.001,1KG_EUR_AF,TSPEAR
502438,21:45936562:C>T,NM_144991.2:c.1566+5204G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,5.895,\N,\N,TSPEAR
502439,21:45936568:G>A,NM_144991.2:c.1566+5198C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.235,0.0008,1KG_AFR_AF,TSPEAR
502440,21:45936586:A>G,NM_144991.2:c.1566+5180T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,2.954,\N,\N,TSPEAR
502441,21:45936602:T>A,NM_144991.2:c.1566+5164A>T,\N,\N,9/11,Unknown significance,\N,intron_variant,5.607,0.0014,1KG_AMR_AF,TSPEAR
502442,21:45936608:G>T,NM_144991.2:c.1566+5158C>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.605,\N,\N,TSPEAR
502443,21:45936610:G>A,NM_144991.2:c.1566+5156C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.766,0.0008,1KG_AFR_AF,TSPEAR
502444,21:45936611:C>A,NM_144991.2:c.1566+5155G>T,\N,\N,9/11,Unknown significance,\N,intron_variant,6.027,0.001,1KG_SAS_AF,TSPEAR
502445,21:45936621:T>G,NM_144991.2:c.1566+5145A>C,\N,\N,9/11,Unknown significance,\N,intron_variant,4.975,0.001,1KG_SAS_AF,TSPEAR
502446,21:45936657:C>G,NM_144991.2:c.1566+5109G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.824,0.0008,1KG_AFR_AF,TSPEAR
502447,21:45936662:C>T,NM_144991.2:c.1566+5104G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.853,0.0043,1KG_AMR_AF,TSPEAR
502448,21:45936663:G>A,NM_144991.2:c.1566+5103C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.073,0.0014,1KG_AMR_AF,TSPEAR
502449,21:45936684:G>A,NM_144991.2:c.1566+5082C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.978,0.0008,1KG_AFR_AF,TSPEAR
502450,21:45936685:G>A,NM_144991.2:c.1566+5081C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,2.529,\N,\N,TSPEAR
502451,21:45936694:T>TCTATGTACGCTGCTTTTCAACAAGTTTC,NM_144991.2:c.1566+5044_1566+5071dup,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,0.003,1KG_AFR_AF,TSPEAR
502452,21:45936700:T>G,NM_144991.2:c.1566+5066A>C,\N,\N,9/11,Unknown significance,\N,intron_variant,2.957,0.0008,1KG_AFR_AF,TSPEAR
502453,21:45936722:C>T,NM_144991.2:c.1566+5044G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,4.404,0.0014,1KG_AMR_AF,TSPEAR
502454,21:45936724:A>AGTT,NM_144991.2:c.1566+5039_1566+5041dup,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
502455,21:45936725:G>A,NM_144991.2:c.1566+5041C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.058,0.0014,1KG_AMR_AF,TSPEAR
502456,21:45936740:G>T,NM_144991.2:c.1566+5026C>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.473,0.002,1KG_EAS_AF,TSPEAR
502457,21:45936749:TC>T,NM_144991.2:c.1566+5016del,\N,\N,9/11,Benign,\N,intron_variant,0.287,0.0121,1KG_AFR_AF,TSPEAR
502458,21:45936750:C>T,NM_144991.2:c.1566+5016G>A,\N,\N,9/11,Benign,\N,intron_variant,1.629,0.0051,1KG_SAS_AF,TSPEAR
502459,21:45936754:T>C,NM_144991.2:c.1566+5012A>G,\N,\N,9/11,Benign,\N,intron_variant,2.38,0.0051,1KG_SAS_AF,TSPEAR
502460,21:45936766:A>G,NM_144991.2:c.1566+5000T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,1.672,0.002,1KG_EUR_AF,TSPEAR
502461,21:45936782:C>T,NM_144991.2:c.1566+4984G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,8.158,\N,\N,TSPEAR
502462,21:45936785:G>C,NM_144991.2:c.1566+4981C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,3.189,0.001,1KG_EUR_AF,TSPEAR
502463,21:45936793:T>G,NM_144991.2:c.1566+4973A>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.03,\N,\N,TSPEAR
502464,21:45936795:C>T,NM_144991.2:c.1566+4971G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.316,\N,\N,TSPEAR
502465,21:45936796:G>A,NM_144991.2:c.1566+4970C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.308,0.001,1KG_EAS_AF,TSPEAR
502466,21:45936810:C>G,NM_144991.2:c.1566+4956G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,1.717,\N,\N,TSPEAR
502467,21:45936827:C>T,NM_144991.2:c.1566+4939G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,4.226,0.0014,1KG_AMR_AF,TSPEAR
502468,21:45936828:G>A,NM_144991.2:c.1566+4938C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.073,\N,\N,TSPEAR
502469,21:45936848:C>T,NM_144991.2:c.1566+4918G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,4.548,\N,\N,TSPEAR
502470,21:45936864:G>C,NM_144991.2:c.1566+4902C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,1.303,\N,\N,TSPEAR
502471,21:45936881:C>T,NM_144991.2:c.1566+4885G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.471,0.0014,1KG_AMR_AF,TSPEAR
502472,21:45936882:G>A,NM_144991.2:c.1566+4884C>T,\N,\N,9/11,Benign,\N,intron_variant,1.027,0.1664,1KG_AFR_AF,TSPEAR
502473,21:45936914:C>T,NM_144991.2:c.1566+4852G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,5.289,\N,\N,TSPEAR
502474,21:45936932:C>T,NM_144991.2:c.1566+4834G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,5.641,0.001,1KG_EUR_AF,TSPEAR
502475,21:45936935:C>T,NM_144991.2:c.1566+4831G>A,\N,\N,9/11,Benign,\N,intron_variant,6.017,0.0174,1KG_AFR_AF,TSPEAR
502476,21:45936943:G>A,NM_144991.2:c.1566+4823C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,2.435,\N,\N,TSPEAR
502477,21:45936950:G>A,NM_144991.2:c.1566+4816C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.401,\N,\N,TSPEAR
502478,21:45936974:G>A,NM_144991.2:c.1566+4792C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,5.967,\N,\N,TSPEAR
502479,21:45936976:C>T,NM_144991.2:c.1566+4790G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,5.801,0.0014,1KG_AMR_AF,TSPEAR
502480,21:45936989:A>G,NM_144991.2:c.1566+4777T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.432,0.001,1KG_EUR_AF,TSPEAR
502481,21:45937012:A>G,NM_144991.2:c.1566+4754T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.041,\N,\N,TSPEAR
502482,21:45937014:C>T,NM_144991.2:c.1566+4752G>A,\N,\N,9/11,Benign,\N,intron_variant,2.618,0.005,1KG_EAS_AF,TSPEAR
502483,21:45937026:C>T,NM_144991.2:c.1566+4740G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.798,\N,\N,TSPEAR
502484,21:45937029:T>C,NM_144991.2:c.1566+4737A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.342,0.0008,1KG_AFR_AF,TSPEAR
502485,21:45937030:T>G,NM_144991.2:c.1566+4736A>C,\N,\N,9/11,Unknown significance,\N,intron_variant,1.263,0.001,1KG_EAS_AF,TSPEAR
502486,21:45937031:A>AT,NM_144991.2:c.1566+4734dup,\N,\N,9/11,Unknown significance,\N,intron_variant,0.359,\N,\N,TSPEAR
502487,21:45937031:A>G,NM_144991.2:c.1566+4735T>C,\N,\N,9/11,Benign,\N,intron_variant,2.384,0.1483,1KG_AFR_AF,TSPEAR
502488,21:45937032:T>C,NM_144991.2:c.1566+4734A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,1.629,\N,\N,TSPEAR
502489,21:45937039:C>A,NM_144991.2:c.1566+4727G>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.228,\N,\N,TSPEAR
502490,21:45937052:C>T,NM_144991.2:c.1566+4714G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.809,0.0038,1KG_AFR_AF,TSPEAR
502491,21:45937057:G>A,NM_144991.2:c.1566+4709C>T,\N,\N,9/11,Benign,\N,intron_variant,1.702,0.0129,1KG_AFR_AF,TSPEAR
502492,21:45937062:G>A,NM_144991.2:c.1566+4704C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.438,0.001,1KG_EAS_AF,TSPEAR
502493,21:45937071:C>G,NM_144991.2:c.1566+4695G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,2.678,0.0008,1KG_AFR_AF,TSPEAR
502494,21:45937086:G>C,NM_144991.2:c.1566+4680C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,2.524,\N,\N,TSPEAR
502495,21:45937098:G>A,NM_144991.2:c.1566+4668C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,6.661,\N,\N,TSPEAR
502496,21:45937120:T>G,NM_144991.2:c.1566+4646A>C,\N,\N,9/11,Unknown significance,\N,intron_variant,2.047,0.0023,1KG_AFR_AF,TSPEAR
502497,21:45937139:C>T,NM_144991.2:c.1566+4627G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.535,0.0008,1KG_AFR_AF,TSPEAR
502498,21:45937157:T>G,NM_144991.2:c.1566+4609A>C,\N,\N,9/11,Unknown significance,\N,intron_variant,2.876,0.001,1KG_SAS_AF,TSPEAR
502499,21:45937158:C>T,NM_144991.2:c.1566+4608G>A,\N,\N,9/11,Benign,\N,intron_variant,5.555,0.0853,1KG_EAS_AF,TSPEAR
502500,21:45937180:C>G,NM_144991.2:c.1566+4586G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.941,0.001,1KG_SAS_AF,TSPEAR
502501,21:45937186:A>AC,NM_144991.2:c.1566+4579dup,\N,\N,9/11,Benign,\N,intron_variant,0.9,0.0484,1KG_AFR_AF,TSPEAR
502502,21:45937188:C>T,NM_144991.2:c.1566+4578G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,6.376,\N,\N,TSPEAR
502503,21:45937201:C>G,NM_144991.2:c.1566+4565G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.215,0.0038,1KG_AFR_AF,TSPEAR
502504,21:45937202:G>A,NM_144991.2:c.1566+4564C>T,\N,\N,9/11,Benign,\N,intron_variant,3.786,0.0484,1KG_AFR_AF,TSPEAR
502505,21:45937227:T>A,NM_144991.2:c.1566+4539A>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.433,0.002,1KG_EAS_AF,TSPEAR
502506,21:45937237:A>G,NM_144991.2:c.1566+4529T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.091,\N,\N,TSPEAR
502507,21:45937243:C>T,NM_144991.2:c.1566+4523G>A,\N,\N,9/11,Benign,\N,intron_variant,4.283,0.0119,1KG_EAS_AF,TSPEAR
502508,21:45937246:G>A,NM_144991.2:c.1566+4520C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,4.151,\N,\N,TSPEAR
502509,21:45937255:A>T,NM_144991.2:c.1566+4511T>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.109,0.0029,1KG_AMR_AF,TSPEAR
502510,21:45937270:T>TGAGCTGTGAGTACACGTGACACAGGGAC,NM_144991.2:c.1566+4468_1566+4495dup,\N,\N,9/11,Unknown significance,\N,intron_variant,0.234,0.0031,1KG_SAS_AF,TSPEAR
502511,21:45937273:G>A,NM_144991.2:c.1566+4493C>T,\N,\N,9/11,Benign,\N,intron_variant,1.317,0.0121,1KG_AFR_AF,TSPEAR
502512,21:45937302:C>T,NM_144991.2:c.1566+4464G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,4.376,\N,\N,TSPEAR
502513,21:45937315:C>G,NM_144991.2:c.1566+4451G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,6.541,\N,\N,TSPEAR
502514,21:45937325:C>G,NM_144991.2:c.1566+4441G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,3.734,0.003,1KG_EUR_AF,TSPEAR
502515,21:45937339:G>A,NM_144991.2:c.1566+4427C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.482,\N,\N,TSPEAR
502516,21:45937340:G>T,NM_144991.2:c.1566+4426C>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.477,0.0015,1KG_AFR_AF,TSPEAR
502517,21:45937343:G>A,NM_144991.2:c.1566+4423C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.645,\N,\N,TSPEAR
502518,21:45937344:T>G,NM_144991.2:c.1566+4422A>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.083,0.001,1KG_SAS_AF,TSPEAR
502519,21:45937351:A>T,NM_144991.2:c.1566+4415T>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.239,0.001,1KG_SAS_AF,TSPEAR
502520,21:45937358:G>C,NM_144991.2:c.1566+4408C>G,\N,\N,9/11,Benign,\N,intron_variant,0.069,0.0129,1KG_EAS_AF,TSPEAR
502521,21:45937372:T>A,NM_144991.2:c.1566+4394A>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.715,0.001,1KG_EAS_AF,TSPEAR
502522,21:45937379:A>G,NM_144991.2:c.1566+4387T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.917,0.0015,1KG_AFR_AF,TSPEAR
502523,21:45937396:TGTGAGGACAC>T,NM_144991.2:c.1566+4360_1566+4369del,\N,\N,9/11,Unknown significance,\N,intron_variant,10.56,0.0041,1KG_SAS_AF,TSPEAR
502524,21:45937407:G>A,NM_144991.2:c.1566+4359C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.31,\N,\N,TSPEAR
502525,21:45937412:T>C,NM_144991.2:c.1566+4354A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.305,\N,\N,TSPEAR
502526,21:45937441:C>G,NM_144991.2:c.1566+4325G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,6.794,\N,\N,TSPEAR
502527,21:45937444:G>T,NM_144991.2:c.1566+4322C>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.761,\N,\N,TSPEAR
502528,21:45937461:G>A,NM_144991.2:c.1566+4305C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,4.881,0.0029,1KG_AMR_AF,TSPEAR
502529,21:45937469:A>T,NM_144991.2:c.1566+4297T>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.382,\N,\N,TSPEAR
502530,21:45937470:G>A,NM_144991.2:c.1566+4296C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,4.234,\N,\N,TSPEAR
502531,21:45937476:G>A,NM_144991.2:c.1566+4290C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.223,0.001,1KG_SAS_AF,TSPEAR
502532,21:45937481:C>T,NM_144991.2:c.1566+4285G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,5.684,0.001,1KG_SAS_AF,TSPEAR
502533,21:45937502:C>G,NM_144991.2:c.1566+4264G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,3.797,\N,\N,TSPEAR
502534,21:45937502:C>T,NM_144991.2:c.1566+4264G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,6.086,0.002,1KG_SAS_AF,TSPEAR
502535,21:45937503:G>A,NM_144991.2:c.1566+4263C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,2.744,0.001,1KG_EUR_AF,TSPEAR
502536,21:45937505:G>C,NM_144991.2:c.1566+4261C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,1.504,0.001,1KG_EUR_AF,TSPEAR
502537,21:45937507:G>A,NM_144991.2:c.1566+4259C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.671,\N,\N,TSPEAR
502538,21:45937521:A>C,NM_144991.2:c.1566+4245T>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.416,\N,\N,TSPEAR
502539,21:45937532:GAACT>G,NM_144991.2:c.1566+4230_1566+4233del,\N,\N,9/11,Unknown significance,\N,intron_variant,5.717,0.0015,1KG_AFR_AF,TSPEAR
502540,21:45937535:C>T,NM_144991.2:c.1566+4231G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.618,\N,\N,TSPEAR
502541,21:45937560:T>A,NM_144991.2:c.1566+4206A>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.167,0.0029,1KG_AMR_AF,TSPEAR
502542,21:45937563:CAT>C,NM_144991.2:c.1566+4201_1566+4202del,\N,\N,9/11,Unknown significance,\N,intron_variant,8.334,\N,\N,TSPEAR
502543,21:45937580:TGGCAGTGGCCAGCGTCCTTGTCCTGCGGG>T,NM_144991.2:c.1566+4157_1566+4185del,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,0.003,1KG_EUR_AF,TSPEAR
502544,21:45937594:G>A,NM_144991.2:c.1566+4172C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,4.444,0.0014,1KG_AMR_AF,TSPEAR
502545,21:45937607:G>A,NM_144991.2:c.1566+4159C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.118,0.001,1KG_EAS_AF,TSPEAR
502546,21:45937613:T>G,NM_144991.2:c.1566+4153A>C,\N,\N,9/11,Benign,\N,intron_variant,0.413,0.1157,1KG_AFR_AF,TSPEAR
502547,21:45937617:T>C,NM_144991.2:c.1566+4149A>G,\N,\N,9/11,Benign,\N,intron_variant,0.976,0.2322,1KG_AFR_AF,TSPEAR
502548,21:45937617:TG>CA,NM_144991.2:c.1566+4148_1566+4149inv,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
502549,21:45937618:G>A,NM_144991.2:c.1566+4148C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.547,0.0015,1KG_AFR_AF,TSPEAR
502550,21:45937628:C>T,NM_144991.2:c.1566+4138G>A,\N,\N,9/11,Benign,\N,intron_variant,5.237,0.00617284,EXAC_EAS_AF,TSPEAR
502551,21:45937629:G>A,NM_144991.2:c.1566+4137C>T,\N,\N,9/11,Benign,\N,intron_variant,3.197,0.0340909,EXAC_FIN_AF,TSPEAR
502552,21:45937630:C>A,NM_144991.2:c.1566+4136G>T,\N,\N,9/11,Unknown significance,\N,intron_variant,6.136,0.000130514,EXAC_SAS_AF,TSPEAR
502553,21:45937636:G>A,NM_144991.2:c.1566+4130C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,4.28,\N,\N,TSPEAR
502554,21:45937638:A>C,NM_144991.2:c.1566+4128T>G,\N,\N,9/11,Benign,\N,intron_variant,1.266,0.0089,1KG_EAS_AF,TSPEAR
502555,21:45937646:C>A,NM_144991.2:c.1566+4120G>T,\N,\N,9/11,Unknown significance,\N,intron_variant,7.524,0.000130446,EXAC_SAS_AF,TSPEAR
502556,21:45937658:C>T,NM_144991.2:c.1566+4108G>A,\N,\N,9/11,Benign,\N,intron_variant,4.048,0.0446,1KG_AFR_AF,TSPEAR
502557,21:45937668:GGGCTGCCGATGGGAAATCCCA>G,NM_144991.2:c.1566+4077_1566+4097del,\N,\N,9/11,Unknown significance,\N,intron_variant,11.35,\N,\N,TSPEAR
502558,21:45937675:C>T,NM_144991.2:c.1566+4091G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,5.301,0.00130446,EXAC_SAS_AF,TSPEAR
502559,21:45937696:C>T,NM_144991.2:c.1566+4070G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,16.19,0.0023,1KG_AFR_AF,TSPEAR
502560,21:45937699:G>A,NM_144991.2:c.1566+4067C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,9.201,\N,\N,TSPEAR
502561,21:45937704:C>T,NM_144991.2:c.1566+4062G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,8.981,\N,\N,TSPEAR
502562,21:45937715:G>A,NM_144991.2:c.1566+4051C>T,\N,\N,9/11,Benign,\N,intron_variant,2.79,0.00531915,EXAC_OTH_AF,TSPEAR
502563,21:45937720:T>A,NR_026547.1:n.621+2T>A,\N,\N,1/2,Unknown significance,\N,splice_donor_variant&non_coding_transcript_variant,4.45,0.0014,1KG_AMR_AF,TSPEAR
502564,21:45937722:A>G,NR_026547.1:n.621+4A>G,\N,\N,1/2,Unknown significance,\N,splice_region_variant&intron_variant&non_coding_transcript_variant,3.538,0.000130446,EXAC_SAS_AF,TSPEAR
502565,21:45937739:C>T,NM_144991.2:c.1566+4027G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,7.4,0.000391338,EXAC_SAS_AF,TSPEAR
502566,21:45937740:G>A,NM_144991.2:c.1566+4026C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.995,0.0015,1KG_AFR_AF,TSPEAR
502567,21:45937749:G>A,NM_144991.2:c.1566+4017C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.658,0.0008,1KG_AFR_AF,TSPEAR
502568,21:45937751:T>C,NM_144991.2:c.1566+4015A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,1.383,\N,\N,TSPEAR
502569,21:45937755:C>T,NM_144991.2:c.1566+4011G>A,\N,\N,9/11,Benign,\N,intron_variant,0.496,0.013245,EXAC_AFR_AF,TSPEAR
502570,21:45937760:T>C,NM_144991.2:c.1566+4006A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.064,0.000189107,EXAC_NFE_AF,TSPEAR
502571,21:45937765:G>C,NM_144991.2:c.1566+4001C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.467,0.00175747,EXAC_FIN_AF,TSPEAR
502572,21:45937782:C>T,NM_144991.2:c.1566+3984G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.169,0.001,1KG_EAS_AF,TSPEAR
502573,21:45937784:G>GT,NM_144991.2:c.1566+3981dup,\N,\N,9/11,Benign,\N,intron_variant,1.163,0.0378,1KG_AFR_AF,TSPEAR
502574,21:45937790:T>C,NM_144991.2:c.1566+3976A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.144,0.001,1KG_EAS_AF,TSPEAR
502575,21:45937793:A>G,NM_144991.2:c.1566+3973T>C,\N,\N,9/11,Benign,\N,intron_variant,1.714,0.0051,1KG_SAS_AF,TSPEAR
502576,21:45937796:C>G,NM_144991.2:c.1566+3970G>C,\N,\N,9/11,Benign,\N,intron_variant,2.455,0.1165,1KG_AFR_AF,TSPEAR
502577,21:45937815:C>T,NM_144991.2:c.1566+3951G>A,\N,\N,9/11,Benign,\N,intron_variant,0.829,0.1104,1KG_AFR_AF,TSPEAR
502578,21:45937827:C>CCT,NM_144991.2:c.1566+3937_1566+3938dup,\N,\N,9/11,Benign,\N,intron_variant,5.803,0.0123,1KG_SAS_AF,TSPEAR
502579,21:45937829:T>C,NM_144991.2:c.1566+3937A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,2.129,0.001,1KG_SAS_AF,TSPEAR
502580,21:45937833:CT>C,NM_144991.2:c.1566+3932del,\N,\N,9/11,Unknown significance,\N,intron_variant,5.675,0.0031,1KG_SAS_AF,TSPEAR
502581,21:45937841:T>TC,NM_144991.2:c.1566+3924dup,\N,\N,9/11,Unknown significance,\N,intron_variant,1.003,\N,\N,TSPEAR
502582,21:45937863:TAC>T,NM_144991.2:c.1566+3901_1566+3902del,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
502583,21:45937873:C>A,NM_144991.2:c.1566+3893G>T,\N,\N,9/11,Benign,\N,intron_variant,4.341,0.0061,1KG_SAS_AF,TSPEAR
502584,21:45937887:G>A,NM_144991.2:c.1566+3879C>T,\N,\N,9/11,Benign,\N,intron_variant,8.065,0.0061,1KG_AFR_AF,TSPEAR
502585,21:45937917:C>T,NM_144991.2:c.1566+3849G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.028,0.0008,1KG_AFR_AF,TSPEAR
502586,21:45937924:C>T,NM_144991.2:c.1566+3842G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.138,0.001,1KG_SAS_AF,TSPEAR
502587,21:45937938:CATGTTA>C,NM_144991.2:c.1566+3822_1566+3827del,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
502588,21:45937940:T>C,NM_144991.2:c.1566+3826A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,1.623,\N,\N,TSPEAR
502589,21:45937960:T>G,NM_144991.2:c.1566+3806A>C,\N,\N,9/11,Unknown significance,\N,intron_variant,8.822,\N,\N,TSPEAR
502590,21:45937976:A>G,NM_144991.2:c.1566+3790T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,3.249,0.0008,1KG_AFR_AF,TSPEAR
502591,21:45937984:T>C,NM_144991.2:c.1566+3782A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,1.141,\N,\N,TSPEAR
502592,21:45937991:GCTCT>G,NM_144991.2:c.1566+3771_1566+3774del,\N,\N,9/11,Benign,\N,intron_variant,2.393,0.006,1KG_EAS_AF,TSPEAR
502593,21:45937993:T>G,NM_144991.2:c.1566+3773A>C,\N,\N,9/11,Unknown significance,\N,intron_variant,2.028,0.0038,1KG_AFR_AF,TSPEAR
502594,21:45937994:CTCTG>C,NM_144991.2:c.1566+3768_1566+3771del,\N,\N,9/11,Unknown significance,\N,intron_variant,1.781,\N,\N,TSPEAR
502595,21:45938003:A>T,NM_144991.2:c.1566+3763T>A,\N,\N,9/11,Benign,\N,intron_variant,0.257,0.0061,1KG_AFR_AF,TSPEAR
502596,21:45938012:A>G,NM_144991.2:c.1566+3754T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.069,0.002,1KG_EAS_AF,TSPEAR
502597,21:45938015:T>C,NM_144991.2:c.1566+3751A>G,\N,\N,9/11,Benign,\N,intron_variant,0.155,0.4085,1KG_AFR_AF,TSPEAR
502598,21:45938024:G>A,NM_144991.2:c.1566+3742C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.418,0.0008,1KG_AFR_AF,TSPEAR
502599,21:45938047:A>G,NM_144991.2:c.1566+3719T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.519,0.001,1KG_EAS_AF,TSPEAR
502600,21:45938066:A>G,NM_144991.2:c.1566+3700T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.64,\N,\N,TSPEAR
502601,21:45938069:T>TA,NM_144991.2:c.1566+3696dup,\N,\N,9/11,Benign,\N,intron_variant,1.149,0.0734,1KG_AFR_AF,TSPEAR
502602,21:45938076:A>G,NM_144991.2:c.1566+3690T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,7.952,\N,\N,TSPEAR
502603,21:45938094:A>G,NM_144991.2:c.1566+3672T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,4.374,0.004,1KG_EAS_AF,TSPEAR
502604,21:45938107:T>C,NM_144991.2:c.1566+3659A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,2.959,\N,\N,TSPEAR
502605,21:45938109:T>G,NM_144991.2:c.1566+3657A>C,\N,\N,9/11,Unknown significance,\N,intron_variant,1.35,0.0008,1KG_AFR_AF,TSPEAR
502606,21:45938110:T>C,NM_144991.2:c.1566+3656A>G,\N,\N,9/11,Benign,\N,intron_variant,0.197,0.0178571,EXAC_FIN_AF,TSPEAR
502607,21:45938115:C>G,NM_144991.2:c.1566+3651G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.403,0.002,1KG_SAS_AF,TSPEAR
502608,21:45938125:T>C,NM_144991.2:c.1566+3641A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.272,0.000159185,EXAC_SAS_AF,TSPEAR
502609,21:45938138:G>C,NR_026547.1:n.622-4G>C,\N,\N,1/2,Unknown significance,\N,splice_region_variant&intron_variant&non_coding_transcript_variant,0.299,0.000292141,EXAC_SAS_AF,TSPEAR
502610,21:45938162:C>T,NM_144991.2:c.1566+3604G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,7.221,\N,\N,TSPEAR
502611,21:45938166:C>T,NM_144991.2:c.1566+3600G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,19.71,\N,\N,TSPEAR
502612,21:45938181:G>A,NM_144991.2:c.1566+3585C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,12.19,0.000132626,EXAC_SAS_AF,TSPEAR
502613,21:45938190:G>A,NM_144991.2:c.1566+3576C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,16.42,0.00204082,EXAC_EAS_AF,TSPEAR
502614,21:45938195:G>C,NM_144991.2:c.1566+3571C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.108,0.0041,1KG_SAS_AF,TSPEAR
502615,21:45938219:C>T,NR_026547.1:n.695+4C>T,\N,\N,2/2,Benign,\N,splice_region_variant&intron_variant&non_coding_transcript_variant,7.143,0.0454,1KG_AFR_AF,TSPEAR
502616,21:45938222:TCTGGGGCA>T,NR_026547.1:n.695+16_695+23del,\N,\N,2/2,Unknown significance,\N,splice_region_variant&intron_variant&non_coding_transcript_variant,6.183,\N,\N,TSPEAR
502617,21:45938231:C>A,NM_144991.2:c.1566+3535G>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.908,0.000196696,EXAC_NFE_AF,TSPEAR
502618,21:45938240:C>A,NM_144991.2:c.1566+3526G>T,\N,\N,9/11,Unknown significance,\N,intron_variant,5.174,0.000142288,EXAC_SAS_AF,TSPEAR
502619,21:45938245:G>A,NM_144991.2:c.1566+3521C>T,\N,\N,9/11,Benign,\N,intron_variant,3.243,0.0051,1KG_SAS_AF,TSPEAR
502620,21:45938263:G>T,NM_144991.2:c.1566+3503C>A,\N,\N,9/11,Benign,\N,intron_variant,0.267,0.0053,1KG_AFR_AF,TSPEAR
502621,21:45938264:TGAA>T,NM_144991.2:c.1566+3499_1566+3501del,\N,\N,9/11,Unknown significance,\N,intron_variant,4.226,0.000152952,EXAC_SAS_AF,TSPEAR
502622,21:45938264:T>C,NM_144991.2:c.1566+3502A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,1.812,0.000152952,EXAC_SAS_AF,TSPEAR
502623,21:45938270:A>C,NM_144991.2:c.1566+3496T>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.695,0.0014,1KG_AMR_AF,TSPEAR
502624,21:45938275:C>T,NM_144991.2:c.1566+3491G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.086,0.001,1KG_EAS_AF,TSPEAR
502625,21:45938288:T>C,NM_144991.2:c.1566+3478A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,4.424,\N,\N,TSPEAR
502626,21:45938293:G>A,NM_144991.2:c.1566+3473C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.463,\N,\N,TSPEAR
502627,21:45938318:G>A,NM_144991.2:c.1566+3448C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.556,\N,\N,TSPEAR
502628,21:45938329:A>C,NM_144991.2:c.1566+3437T>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.711,0.0014,1KG_AMR_AF,TSPEAR
502629,21:45938352:C>T,NM_144991.2:c.1566+3414G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.086,\N,\N,TSPEAR
502630,21:45938363:A>G,NM_144991.2:c.1566+3403T>C,\N,\N,9/11,Benign,\N,intron_variant,9.178,0.0121,1KG_AFR_AF,TSPEAR
502631,21:45938368:C>T,NM_144991.2:c.1566+3398G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,9.204,0.002,1KG_SAS_AF,TSPEAR
502632,21:45938379:C>A,NM_144991.2:c.1566+3387G>T,\N,\N,9/11,Unknown significance,\N,intron_variant,6.033,0.003,1KG_EAS_AF,TSPEAR
502633,21:45938383:C>A,NM_144991.2:c.1566+3383G>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.036,0.0008,1KG_AFR_AF,TSPEAR
502634,21:45938383:C>CT,NM_144991.2:c.1566+3382dup,\N,\N,9/11,Unknown significance,\N,intron_variant,5.046,\N,\N,TSPEAR
502635,21:45938399:T>G,NM_144991.2:c.1566+3367A>C,\N,\N,9/11,Benign,\N,intron_variant,3.05,0.0477,1KG_AFR_AF,TSPEAR
502636,21:45938407:T>A,NM_144991.2:c.1566+3359A>T,\N,\N,9/11,Unknown significance,\N,intron_variant,4.46,\N,\N,TSPEAR
502637,21:45938423:C>T,NM_144991.2:c.1566+3343G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.91,0.001,1KG_SAS_AF,TSPEAR
502638,21:45938431:C>T,NM_144991.2:c.1566+3335G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.037,0.001,1KG_SAS_AF,TSPEAR
502639,21:45938458:A>G,NM_144991.2:c.1566+3308T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.541,\N,\N,TSPEAR
502640,21:45938467:T>A,NM_144991.2:c.1566+3299A>T,\N,\N,9/11,Unknown significance,\N,intron_variant,4.936,0.0008,1KG_AFR_AF,TSPEAR
502641,21:45938478:C>T,NM_144991.2:c.1566+3288G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.39,\N,\N,TSPEAR
502642,21:45938479:G>A,NM_144991.2:c.1566+3287C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.8,0.000193798,EXAC_NFE_AF,TSPEAR
502643,21:45938489:C>G,NM_144991.2:c.1566+3277G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,3.829,0.00283554,EXAC_AFR_AF,TSPEAR
502644,21:45938497:G>A,NM_144991.2:c.1566+3269C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.213,\N,\N,TSPEAR
502645,21:45938502:T>C,NM_144991.2:c.1566+3264A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,1.36,0.002,1KG_SAS_AF,TSPEAR
502646,21:45938504:C>T,NR_026547.1:n.696-7C>T,\N,\N,2/2,Unknown significance,\N,splice_region_variant&intron_variant&non_coding_transcript_variant,1.29,\N,\N,TSPEAR
502647,21:45938516:G>A,NM_144991.2:c.1566+3250C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,2.38,0.001,1KG_SAS_AF,TSPEAR
502648,21:45938517:C>T,NM_144991.2:c.1566+3249G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,11.98,\N,\N,TSPEAR
502649,21:45938518:G>A,NM_144991.2:c.1566+3248C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,12.83,0.000961538,EXAC_FIN_AF,TSPEAR
502650,21:45938535:C>A,NM_144991.2:c.1566+3231G>T,\N,\N,9/11,Unknown significance,\N,intron_variant,11.58,\N,\N,TSPEAR
502651,21:45938536:C>A,NM_144991.2:c.1566+3230G>T,\N,\N,9/11,Unknown significance,\N,intron_variant,14.13,0.00384615,EXAC_AMR_AF,TSPEAR
502652,21:45938547:C>T,NM_144991.2:c.1566+3219G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,10.55,0.000857633,EXAC_FIN_AF,TSPEAR
502653,21:45938548:GC>G,NM_144991.2:c.1566+3217del,\N,\N,9/11,Unknown significance,\N,intron_variant,11.89,\N,\N,TSPEAR
502654,21:45938549:C>T,NM_144991.2:c.1566+3217G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.029,0.000198334,EXAC_NFE_AF,TSPEAR
502655,21:45938559:C>T,NM_144991.2:c.1566+3207G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,7.665,\N,\N,TSPEAR
502656,21:45938561:C>G,NM_144991.2:c.1566+3205G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,13.07,\N,\N,TSPEAR
502657,21:45938573:C>A,NM_144991.2:c.1566+3193G>T,\N,\N,9/11,Unknown significance,\N,intron_variant,32,\N,\N,TSPEAR
502658,21:45938573:C>G,NM_144991.2:c.1566+3193G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,15.53,\N,\N,TSPEAR
502659,21:45938573:C>T,NM_144991.2:c.1566+3193G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,15.55,\N,\N,TSPEAR
502660,21:45938600:C>T,NM_144991.2:c.1566+3166G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.047,0.00429185,EXAC_EAS_AF,TSPEAR
502661,21:45938612:G>A,NM_144991.2:c.1566+3154C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,2.047,\N,\N,TSPEAR
502662,21:45938616:A>G,NM_144991.2:c.1566+3150T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.574,0.001,1KG_SAS_AF,TSPEAR
502663,21:45938622:T>C,NM_144991.2:c.1566+3144A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.958,\N,\N,TSPEAR
502664,21:45938635:C>A,NM_144991.2:c.1566+3131G>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.11,\N,\N,TSPEAR
502665,21:45938644:G>C,NM_144991.2:c.1566+3122C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.175,\N,\N,TSPEAR
502666,21:45938681:A>G,NM_144991.2:c.1566+3085T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,1.676,0.001,1KG_EAS_AF,TSPEAR
502667,21:45938711:G>A,NM_144991.2:c.1566+3055C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.062,\N,\N,TSPEAR
502668,21:45938731:G>A,NM_144991.2:c.1566+3035C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.054,\N,\N,TSPEAR
502669,21:45938740:A>C,NM_144991.2:c.1566+3026T>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.938,\N,\N,TSPEAR
502670,21:45938745:G>A,NM_144991.2:c.1566+3021C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.099,0.001,1KG_EAS_AF,TSPEAR
502671,21:45938760:G>A,NM_144991.2:c.1566+3006C>T,\N,\N,9/11,Benign,\N,intron_variant,1.167,0.0219,1KG_EUR_AF,TSPEAR
502672,21:45938788:A>T,NM_144991.2:c.1566+2978T>A,\N,\N,9/11,Benign,\N,intron_variant,0.665,0.0092,1KG_SAS_AF,TSPEAR
502673,21:45938816:G>A,NM_144991.2:c.1566+2950C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.922,\N,\N,TSPEAR
502674,21:45938833:G>A,NM_144991.2:c.1566+2933C>T,\N,\N,9/11,Benign,\N,intron_variant,0.059,0.0227,1KG_AFR_AF,TSPEAR
502675,21:45938840:T>C,NM_144991.2:c.1566+2926A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,1.464,0.0041,1KG_SAS_AF,TSPEAR
502676,21:45938861:A>G,NM_144991.2:c.1566+2905T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.13,\N,\N,TSPEAR
502677,21:45938874:C>A,NM_144991.2:c.1566+2892G>T,\N,\N,9/11,Benign,\N,intron_variant,0.906,0.0537,1KG_AFR_AF,TSPEAR
502678,21:45938881:G>A,NM_144991.2:c.1566+2885C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.169,0.0014,1KG_AMR_AF,TSPEAR
502679,21:45938891:G>A,NM_144991.2:c.1566+2875C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.267,0.001,1KG_SAS_AF,TSPEAR
502680,21:45938907:TTTG>T,NM_144991.2:c.1566+2856_1566+2858del,\N,\N,9/11,Benign,\N,intron_variant,1.934,0.008,1KG_EUR_AF,TSPEAR
502681,21:45938913:G>GT,NM_144991.2:c.1566+2852dup,\N,\N,9/11,Unknown significance,\N,intron_variant,0.779,\N,\N,TSPEAR
502682,21:45938913:GTTTT>G,NM_144991.2:c.1566+2849_1566+2852del,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,0.002,1KG_EAS_AF,TSPEAR
502683,21:45938943:A>G,NM_144991.2:c.1566+2823T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,6.224,0.0008,1KG_AFR_AF,TSPEAR
502684,21:45938958:C>T,NM_144991.2:c.1566+2808G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.053,\N,\N,TSPEAR
502685,21:45938965:G>C,NM_144991.2:c.1566+2801C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.423,\N,\N,TSPEAR
502686,21:45938966:C>T,NM_144991.2:c.1566+2800G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.38,0.0008,1KG_AFR_AF,TSPEAR
502687,21:45938972:C>T,NM_144991.2:c.1566+2794G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.316,0.001,1KG_EAS_AF|1KG_SAS_AF,TSPEAR
502688,21:45938973:G>A,NM_144991.2:c.1566+2793C>T,\N,\N,9/11,Benign,\N,intron_variant,1.417,0.0083,1KG_AFR_AF,TSPEAR
502689,21:45938974:T>C,NM_144991.2:c.1566+2792A>G,\N,\N,9/11,Benign,\N,intron_variant,0.078,0.0129,1KG_EUR_AF,TSPEAR
502690,21:45938975:G>A,NM_144991.2:c.1566+2791C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.707,0.0008,1KG_AFR_AF,TSPEAR
502691,21:45938998:G>A,NM_144991.2:c.1566+2768C>T,\N,\N,9/11,Benign,\N,intron_variant,0.23,0.0119,1KG_EUR_AF,TSPEAR
502692,21:45939049:T>C,NM_144991.2:c.1566+2717A>G,\N,\N,9/11,Benign,\N,intron_variant,0.206,0.0169,1KG_EAS_AF,TSPEAR
502693,21:45939056:T>C,NM_144991.2:c.1566+2710A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.086,0.0008,1KG_AFR_AF,TSPEAR
502694,21:45939057:A>G,NM_144991.2:c.1566+2709T>C,\N,\N,9/11,Benign,\N,intron_variant,0.159,0.3419,1KG_AFR_AF,TSPEAR
502695,21:45939068:T>C,NM_144991.2:c.1566+2698A>G,\N,\N,9/11,Benign,\N,intron_variant,0.074,0.5333,1KG_AFR_AF,TSPEAR
502696,21:45939068:TG>CA,NM_144991.2:c.1566+2697_1566+2698inv,\N,\N,9/11,Unknown significance,\N,intron_variant,1.462,\N,\N,TSPEAR
502697,21:45939069:G>A,NM_144991.2:c.1566+2697C>T,\N,\N,9/11,Benign,\N,intron_variant,2.114,0.1104,1KG_AFR_AF,TSPEAR
502698,21:45939072:A>T,NM_144991.2:c.1566+2694T>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.071,0.001,1KG_SAS_AF,TSPEAR
502699,21:45939078:A>AT,NM_144991.2:c.1566+2687dup,\N,\N,9/11,Benign,\N,intron_variant,0.337,0.112,1KG_AFR_AF,TSPEAR
502700,21:45939105:A>G,NM_144991.2:c.1566+2661T>C,\N,\N,9/11,Benign,\N,intron_variant,0.142,0.5855,1KG_AFR_AF,TSPEAR
502701,21:45939116:G>A,NM_144991.2:c.1566+2650C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.198,\N,\N,TSPEAR
502702,21:45939126:G>A,NM_144991.2:c.1566+2640C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.799,0.0014,1KG_AMR_AF,TSPEAR
502703,21:45939130:G>A,NM_144991.2:c.1566+2636C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.295,0.001,1KG_EUR_AF,TSPEAR
502704,21:45939147:C>A,NM_144991.2:c.1566+2619G>T,\N,\N,9/11,Benign,\N,intron_variant,3.692,0.006,1KG_EUR_AF,TSPEAR
502705,21:45939156:C>T,NM_144991.2:c.1566+2610G>A,\N,\N,9/11,Benign,\N,intron_variant,0.178,0.0091,1KG_AFR_AF,TSPEAR
502706,21:45939157:G>A,NM_144991.2:c.1566+2609C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.49,0.0008,1KG_AFR_AF,TSPEAR
502707,21:45939167:G>A,NM_144991.2:c.1566+2599C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.337,0.001,1KG_EAS_AF,TSPEAR
502708,21:45939173:C>A,NM_144991.2:c.1566+2593G>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.167,0.001,1KG_SAS_AF,TSPEAR
502709,21:45939194:T>G,NM_144991.2:c.1566+2572A>C,\N,\N,9/11,Benign,\N,intron_variant,1.648,0.5522,1KG_AFR_AF,TSPEAR
502710,21:45939206:G>A,NM_144991.2:c.1566+2560C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.363,0.002,1KG_SAS_AF,TSPEAR
502711,21:45939213:C>T,NM_144991.2:c.1566+2553G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.072,\N,\N,TSPEAR
502712,21:45939243:G>A,NM_144991.2:c.1566+2523C>T,\N,\N,9/11,Benign,\N,intron_variant,3.351,0.0106,1KG_AFR_AF,TSPEAR
502713,21:45939245:G>A,NM_144991.2:c.1566+2521C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.072,0.003,1KG_EAS_AF,TSPEAR
502714,21:45939250:G>A,NM_144991.2:c.1566+2516C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.006,0.0029,1KG_AMR_AF,TSPEAR
502715,21:45939252:G>A,NM_144991.2:c.1566+2514C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,2.758,\N,\N,TSPEAR
502716,21:45939276:C>G,NM_144991.2:c.1566+2490G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,1.421,0.001,1KG_EUR_AF,TSPEAR
502717,21:45939288:C>T,NM_144991.2:c.1566+2478G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.45,0.001,1KG_EAS_AF,TSPEAR
502718,21:45939289:G>A,NM_144991.2:c.1566+2477C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,2.831,\N,\N,TSPEAR
502719,21:45939290:C>T,NM_144991.2:c.1566+2476G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.028,0.001,1KG_SAS_AF,TSPEAR
502720,21:45939301:A>T,NM_144991.2:c.1566+2465T>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.037,0.0038,1KG_AFR_AF,TSPEAR
502721,21:45939315:T>C,NM_144991.2:c.1566+2451A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,1.379,\N,\N,TSPEAR
502722,21:45939317:C>T,NM_144991.2:c.1566+2449G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.747,0.002,1KG_SAS_AF,TSPEAR
502723,21:45939324:C>CA,NM_144991.2:c.1566+2441dup,\N,\N,9/11,Benign,\N,intron_variant,2.454,0.5469,1KG_AFR_AF,TSPEAR
502724,21:45939326:A>AC,NM_144991.2:c.1566+2439dup,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
502725,21:45939387:C>T,NM_144991.2:c.1566+2379G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,9.232,\N,\N,TSPEAR
502726,21:45939395:T>G,NM_144991.2:c.1566+2371A>C,\N,\N,9/11,Unknown significance,\N,intron_variant,8.677,0.001,1KG_EUR_AF,TSPEAR
502727,21:45939398:G>A,NM_144991.2:c.1566+2368C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,7.93,0.001,1KG_EUR_AF,TSPEAR
502728,21:45939417:C>T,NM_144991.2:c.1566+2349G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.315,0.0045,1KG_AFR_AF,TSPEAR
502729,21:45939418:G>A,NM_144991.2:c.1566+2348C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,4.131,\N,\N,TSPEAR
502730,21:45939428:G>T,NM_144991.2:c.1566+2338C>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.394,\N,\N,TSPEAR
502731,21:45939445:C>T,NM_144991.2:c.1566+2321G>A,\N,\N,9/11,Benign,\N,intron_variant,0.96,0.0091,1KG_AFR_AF,TSPEAR
502732,21:45939446:G>A,NM_144991.2:c.1566+2320C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.274,0.002,1KG_EAS_AF,TSPEAR
502733,21:45939449:G>C,NM_144991.2:c.1566+2317C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.216,\N,\N,TSPEAR
502734,21:45939452:C>T,NM_144991.2:c.1566+2314G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.705,\N,\N,TSPEAR
502735,21:45939453:G>A,NM_144991.2:c.1566+2313C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.918,\N,\N,TSPEAR
502736,21:45939464:C>T,NM_144991.2:c.1566+2302G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.45,0.0008,1KG_AFR_AF,TSPEAR
502737,21:45939465:G>A,NM_144991.2:c.1566+2301C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.379,\N,\N,TSPEAR
502738,21:45939487:C>G,NM_144991.2:c.1566+2279G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.287,\N,\N,TSPEAR
502739,21:45939517:C>T,NM_144991.2:c.1566+2249G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.56,\N,\N,TSPEAR
502740,21:45939538:T>C,NM_144991.2:c.1566+2228A>G,\N,\N,9/11,Benign,\N,intron_variant,0.296,0.0053,1KG_AFR_AF,TSPEAR
502741,21:45939556:A>C,NM_144991.2:c.1566+2210T>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.139,\N,\N,TSPEAR
502742,21:45939573:C>T,NM_144991.2:c.1566+2193G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.556,0.0008,1KG_AFR_AF,TSPEAR
502743,21:45939596:C>G,NM_144991.2:c.1566+2170G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.429,\N,\N,TSPEAR
502744,21:45939599:G>A,NM_144991.2:c.1566+2167C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.476,\N,\N,TSPEAR
502745,21:45939607:C>T,NM_144991.2:c.1566+2159G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,6.309,\N,\N,TSPEAR
502746,21:45939608:C>T,NM_144991.2:c.1566+2158G>A,\N,\N,9/11,Benign,\N,intron_variant,7.434,0.0139,1KG_EUR_AF,TSPEAR
502747,21:45939609:G>A,NM_144991.2:c.1566+2157C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.227,0.0029,1KG_AMR_AF,TSPEAR
502748,21:45939614:GCTTGGCTTGATCCCAGTTCTGC>G,NM_144991.2:c.1566+2130_1566+2151del,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,0.003,1KG_EAS_AF,TSPEAR
502749,21:45939630:G>T,NM_144991.2:c.1566+2136C>A,\N,\N,9/11,Unknown significance,\N,intron_variant,6.473,0.0014,1KG_AMR_AF,TSPEAR
502750,21:45939640:G>A,NM_144991.2:c.1566+2126C>T,\N,\N,9/11,Benign,\N,intron_variant,1.135,0.0119,1KG_EAS_AF,TSPEAR
502751,21:45939654:A>G,NM_144991.2:c.1566+2112T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,4.944,0.001,1KG_SAS_AF,TSPEAR
502752,21:45939657:G>A,NM_144991.2:c.1566+2109C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.089,0.0008,1KG_AFR_AF,TSPEAR
502753,21:45939665:C>T,NM_144991.2:c.1566+2101G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,5.499,0.0014,1KG_AMR_AF,TSPEAR
502754,21:45939672:G>A,NM_144991.2:c.1566+2094C>T,\N,\N,9/11,Benign,\N,intron_variant,4.253,0.0091,1KG_AFR_AF,TSPEAR
502755,21:45939713:C>G,NM_144991.2:c.1566+2053G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,3.324,0.0029,1KG_AMR_AF,TSPEAR
502756,21:45939738:C>T,NM_144991.2:c.1566+2028G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,4.492,\N,\N,TSPEAR
502757,21:45939744:C>T,NM_144991.2:c.1566+2022G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.084,\N,\N,TSPEAR
502758,21:45939750:G>A,NM_144991.2:c.1566+2016C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,2.253,\N,\N,TSPEAR
502759,21:45939780:G>A,NM_144991.2:c.1566+1986C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.391,0.001,1KG_EUR_AF,TSPEAR
502760,21:45939801:G>A,NM_144991.2:c.1566+1965C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.95,0.003,1KG_EUR_AF,TSPEAR
502761,21:45939840:A>G,NM_144991.2:c.1566+1926T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.04,0.0008,1KG_AFR_AF,TSPEAR
502762,21:45939887:T>A,NM_144991.2:c.1566+1879A>T,\N,\N,9/11,Benign,\N,intron_variant,3.439,0.034,1KG_AFR_AF,TSPEAR
502763,21:45939894:G>GC,NM_144991.2:c.1566+1871dup,\N,\N,9/11,Unknown significance,\N,intron_variant,1.286,0.0015,1KG_AFR_AF,TSPEAR
502764,21:45939897:C>T,NM_144991.2:c.1566+1869G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,4.938,\N,\N,TSPEAR
502765,21:45939900:G>A,NM_144991.2:c.1566+1866C>T,\N,\N,9/11,Benign,\N,intron_variant,2.198,0.1339,1KG_AFR_AF,TSPEAR
502766,21:45939916:C>T,NM_144991.2:c.1566+1850G>A,\N,\N,9/11,Benign,\N,intron_variant,6.461,0.1657,1KG_AFR_AF,TSPEAR
502767,21:45939918:C>T,NM_144991.2:c.1566+1848G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,4.536,0.001,1KG_SAS_AF,TSPEAR
502768,21:45939934:C>T,NM_144991.2:c.1566+1832G>A,\N,\N,9/11,Benign,\N,intron_variant,0.059,0.005,1KG_EAS_AF,TSPEAR
502769,21:45939943:C>T,NM_144991.2:c.1566+1823G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.476,0.001,1KG_SAS_AF,TSPEAR
502770,21:45939945:C>T,NM_144991.2:c.1566+1821G>A,\N,\N,9/11,Benign,\N,intron_variant,1.411,0.0318,1KG_AFR_AF,TSPEAR
502771,21:45939970:G>A,NM_144991.2:c.1566+1796C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.151,0.001,1KG_EUR_AF,TSPEAR
502772,21:45939990:C>T,NM_144991.2:c.1566+1776G>A,\N,\N,9/11,Benign,\N,intron_variant,9.677,0.0061,1KG_SAS_AF,TSPEAR
502773,21:45940005:C>T,NM_144991.2:c.1566+1761G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,7.641,\N,\N,TSPEAR
502774,21:45940016:C>T,NM_144991.2:c.1566+1750G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.179,0.0008,1KG_AFR_AF,TSPEAR
502775,21:45940017:G>A,NM_144991.2:c.1566+1749C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.193,\N,\N,TSPEAR
502776,21:45940023:G>A,NM_144991.2:c.1566+1743C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.021,\N,\N,TSPEAR
502777,21:45940036:G>A,NM_144991.2:c.1566+1730C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,2.006,\N,\N,TSPEAR
502778,21:45940053:A>G,NM_144991.2:c.1566+1713T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.887,0.0008,1KG_AFR_AF,TSPEAR
502779,21:45940077:C>T,NM_144991.2:c.1566+1689G>A,\N,\N,9/11,Benign,\N,intron_variant,0.172,0.1687,1KG_AFR_AF,TSPEAR
502780,21:45940105:A>G,NM_144991.2:c.1566+1661T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,0.705,0.0008,1KG_AFR_AF,TSPEAR
502781,21:45940127:C>T,NM_144991.2:c.1566+1639G>A,\N,\N,9/11,Benign,\N,intron_variant,0.265,0.0113,1KG_AFR_AF,TSPEAR
502782,21:45940206:A>C,NM_144991.2:c.1566+1560T>G,\N,\N,9/11,Unknown significance,\N,intron_variant,1.514,\N,\N,TSPEAR
502783,21:45940218:C>A,NM_144991.2:c.1566+1548G>T,\N,\N,9/11,Unknown significance,\N,intron_variant,6.181,0.002,1KG_SAS_AF,TSPEAR
502784,21:45940239:G>T,NM_144991.2:c.1566+1527C>A,\N,\N,9/11,Benign,\N,intron_variant,0.069,0.0106,1KG_AFR_AF,TSPEAR
502785,21:45940241:T>C,NM_144991.2:c.1566+1525A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,3.615,\N,\N,TSPEAR
502786,21:45940256:G>A,NM_144991.2:c.1566+1510C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.106,\N,\N,TSPEAR
502787,21:45940266:G>A,NM_144991.2:c.1566+1500C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.169,\N,\N,TSPEAR
502788,21:45940281:C>T,NM_144991.2:c.1566+1485G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.054,0.001,1KG_SAS_AF,TSPEAR
502789,21:45940282:G>A,NM_144991.2:c.1566+1484C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.742,0.004,1KG_EAS_AF,TSPEAR
502790,21:45940288:T>C,NM_144991.2:c.1566+1478A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.317,0.001,1KG_EAS_AF,TSPEAR
502791,21:45940298:C>T,NM_144991.2:c.1566+1468G>A,\N,\N,9/11,Benign,\N,intron_variant,1.011,0.0144,1KG_AFR_AF,TSPEAR
502792,21:45940299:G>A,NM_144991.2:c.1566+1467C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.175,0.0015,1KG_AFR_AF,TSPEAR
502793,21:45940335:G>A,NM_144991.2:c.1566+1431C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.515,0.001,1KG_EUR_AF,TSPEAR
502794,21:45940397:G>A,NM_144991.2:c.1566+1369C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.199,0.001,1KG_SAS_AF,TSPEAR
502795,21:45940407:C>T,NM_144991.2:c.1566+1359G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,4.272,0.001,1KG_EUR_AF,TSPEAR
502796,21:45940434:C>T,NM_144991.2:c.1566+1332G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,5.135,\N,\N,TSPEAR
502797,21:45940456:C>T,NM_144991.2:c.1566+1310G>A,\N,\N,9/11,Benign,\N,intron_variant,5.362,0.0333,1KG_AFR_AF,TSPEAR
502798,21:45940457:G>A,NM_144991.2:c.1566+1309C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,2.662,0.0014,1KG_AMR_AF,TSPEAR
502799,21:45940460:G>C,NM_144991.2:c.1566+1306C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,1.726,\N,\N,TSPEAR
502800,21:45940462:T>C,NM_144991.2:c.1566+1304A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,2.059,0.001,1KG_EAS_AF,TSPEAR
502801,21:45940471:G>A,NM_144991.2:c.1566+1295C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,8.365,\N,\N,TSPEAR
502802,21:45940479:C>T,NM_144991.2:c.1566+1287G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,10.77,\N,\N,TSPEAR
502803,21:45940480:G>A,NM_144991.2:c.1566+1286C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,9.467,\N,\N,TSPEAR
502804,21:45940506:G>A,NM_144991.2:c.1566+1260C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.103,0.0015,1KG_AFR_AF,TSPEAR
502805,21:45940506:G>C,NM_144991.2:c.1566+1260C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.246,\N,\N,TSPEAR
502806,21:45940524:T>C,NM_144991.2:c.1566+1242A>G,\N,\N,9/11,Benign,\N,intron_variant,1.07,0.3517,1KG_AFR_AF,TSPEAR
502807,21:45940537:T>C,NM_144991.2:c.1566+1229A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,2.654,\N,\N,TSPEAR
502808,21:45940598:T>C,NM_144991.2:c.1566+1168A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.733,\N,\N,TSPEAR
502809,21:45940614:C>T,NM_144991.2:c.1566+1152G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,6.19,\N,\N,TSPEAR
502810,21:45940635:GATGT>G,NM_144991.2:c.1566+1127_1566+1130del,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
502811,21:45940655:T>C,NM_144991.2:c.1566+1111A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,1.751,\N,\N,TSPEAR
502812,21:45940681:A>C,NM_144991.2:c.1566+1085T>G,\N,\N,9/11,Benign,\N,intron_variant,8.977,0.006,1KG_EAS_AF,TSPEAR
502813,21:45940685:A>G,NM_144991.2:c.1566+1081T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,9.676,0.0045,1KG_AFR_AF,TSPEAR
502814,21:45940698:A>G,NM_144991.2:c.1566+1068T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,4.185,0.001,1KG_EAS_AF,TSPEAR
502815,21:45940700:C>A,NM_144991.2:c.1566+1066G>T,\N,\N,9/11,Unknown significance,\N,intron_variant,6.426,0.001,1KG_EUR_AF,TSPEAR
502816,21:45940710:C>A,NM_144991.2:c.1566+1056G>T,\N,\N,9/11,Benign,\N,intron_variant,5.886,0.0058,1KG_AMR_AF,TSPEAR
502817,21:45940718:C>T,NM_144991.2:c.1566+1048G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.939,0.001,1KG_EUR_AF,TSPEAR
502818,21:45940719:A>C,NM_144991.2:c.1566+1047T>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.18,\N,\N,TSPEAR
502819,21:45940740:G>A,NM_144991.2:c.1566+1026C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,7.139,\N,\N,TSPEAR
502820,21:45940764:G>C,NM_144991.2:c.1566+1002C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.644,\N,\N,TSPEAR
502821,21:45940794:G>A,NM_144991.2:c.1566+972C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.045,0.0008,1KG_AFR_AF,TSPEAR
502822,21:45940796:G>A,NM_144991.2:c.1566+970C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.918,\N,\N,TSPEAR
502823,21:45940815:G>A,NM_144991.2:c.1566+951C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.087,\N,\N,TSPEAR
502824,21:45940838:A>G,NM_144991.2:c.1566+928T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,2.843,0.0008,1KG_AFR_AF,TSPEAR
502825,21:45940854:C>T,NM_144991.2:c.1566+912G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.745,0.001,1KG_SAS_AF,TSPEAR
502826,21:45940858:G>T,NM_144991.2:c.1566+908C>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.315,\N,\N,TSPEAR
502827,21:45940874:C>T,NM_144991.2:c.1566+892G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.242,\N,\N,TSPEAR
502828,21:45940889:C>G,NM_144991.2:c.1566+877G>C,\N,\N,9/11,Unknown significance,\N,intron_variant,3.493,\N,\N,TSPEAR
502829,21:45940903:C>T,NM_144991.2:c.1566+863G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,5.447,\N,\N,TSPEAR
502830,21:45940909:C>T,NM_144991.2:c.1566+857G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.197,0.0038,1KG_AFR_AF,TSPEAR
502831,21:45940910:G>A,NM_144991.2:c.1566+856C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.25,0.004,1KG_EAS_AF,TSPEAR
502832,21:45940925:T>C,NM_144991.2:c.1566+841A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,4.161,0.001,1KG_EUR_AF,TSPEAR
502833,21:45940955:C>T,NM_144991.2:c.1566+811G>A,\N,\N,9/11,Benign,\N,intron_variant,3.229,0.0083,1KG_AFR_AF,TSPEAR
502834,21:45940960:CA>C,NM_144991.2:c.1566+805del,\N,\N,9/11,Benign,\N,intron_variant,6.262,0.0051,1KG_SAS_AF,TSPEAR
502835,21:45940990:C>G,NM_144991.2:c.1566+776G>C,\N,\N,9/11,Benign,\N,intron_variant,0.603,0.3517,1KG_AFR_AF,TSPEAR
502836,21:45941017:C>T,NM_144991.2:c.1566+749G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.823,\N,\N,TSPEAR
502837,21:45941051:C>T,NM_144991.2:c.1566+715G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.943,0.002,1KG_SAS_AF,TSPEAR
502838,21:45941080:G>A,NM_144991.2:c.1566+686C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.084,\N,\N,TSPEAR
502839,21:45941110:C>T,NM_144991.2:c.1566+656G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.606,0.0014,1KG_AMR_AF,TSPEAR
502840,21:45941111:G>C,NM_144991.2:c.1566+655C>G,\N,\N,9/11,Benign,\N,intron_variant,0.139,0.006,1KG_EUR_AF,TSPEAR
502841,21:45941124:C>T,NM_144991.2:c.1566+642G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.274,0.001,1KG_EAS_AF,TSPEAR
502842,21:45941130:C>T,NM_144991.2:c.1566+636G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.277,0.0008,1KG_AFR_AF,TSPEAR
502843,21:45941134:T>C,NM_144991.2:c.1566+632A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.086,0.0008,1KG_AFR_AF,TSPEAR
502844,21:45941139:C>T,NM_144991.2:c.1566+627G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,3.633,0.0015,1KG_AFR_AF,TSPEAR
502845,21:45941140:G>A,NM_144991.2:c.1566+626C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.018,0.001,1KG_EAS_AF,TSPEAR
502846,21:45941200:G>A,NM_144991.2:c.1566+566C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,5.63,\N,\N,TSPEAR
502847,21:45941206:C>T,NM_144991.2:c.1566+560G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,8.309,\N,\N,TSPEAR
502848,21:45941232:C>T,NM_144991.2:c.1566+534G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.871,0.001,1KG_SAS_AF,TSPEAR
502849,21:45941237:G>A,NM_144991.2:c.1566+529C>T,\N,\N,9/11,Benign,\N,intron_variant,2.21,0.0189,1KG_EUR_AF,TSPEAR
502850,21:45941261:C>T,NM_144991.2:c.1566+505G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,5.636,0.001,1KG_EUR_AF,TSPEAR
502851,21:45941286:G>A,NM_144991.2:c.1566+480C>T,\N,\N,9/11,Benign,\N,intron_variant,2.843,1,1KG_ALL_AF|1KG_AFR_AF|1KG_AMR_AF|1KG_EAS_AF|1KG_EUR_AF|1KG_SAS_AF,TSPEAR
502852,21:45941309:G>A,NM_144991.2:c.1566+457C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.504,0.0014,1KG_AMR_AF,TSPEAR
502853,21:45941313:C>T,NM_144991.2:c.1566+453G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.019,\N,\N,TSPEAR
502854,21:45941337:C>T,NM_144991.2:c.1566+429G>A,\N,\N,9/11,Benign,\N,intron_variant,0.365,0.0083,1KG_AFR_AF,TSPEAR
502855,21:45941370:G>A,NM_144991.2:c.1566+396C>T,\N,\N,9/11,Benign,\N,intron_variant,4.743,0.1994,1KG_EAS_AF,TSPEAR
502856,21:45941378:G>T,NM_144991.2:c.1566+388C>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.582,\N,\N,TSPEAR
502857,21:45941383:G>T,NM_144991.2:c.1566+383C>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.862,\N,\N,TSPEAR
502858,21:45941392:G>A,NM_144991.2:c.1566+374C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.26,0.001,1KG_EAS_AF,TSPEAR
502859,21:45941393:A>C,NM_144991.2:c.1566+373T>G,\N,\N,9/11,Benign,\N,intron_variant,2.289,0.3517,1KG_AFR_AF,TSPEAR
502860,21:45941395:C>A,NM_144991.2:c.1566+371G>T,\N,\N,9/11,Unknown significance,\N,intron_variant,6.174,0.001,1KG_EAS_AF,TSPEAR
502861,21:45941415:C>T,NM_144991.2:c.1566+351G>A,\N,\N,9/11,Benign,\N,intron_variant,0.547,0.1672,1KG_AFR_AF,TSPEAR
502862,21:45941418:G>A,NM_144991.2:c.1566+348C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.908,0.0008,1KG_AFR_AF,TSPEAR
502863,21:45941455:C>CG,NM_144991.2:c.1566+310dup,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,0.0023,1KG_AFR_AF,TSPEAR
502864,21:45941455:C>T,NM_144991.2:c.1566+311G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.941,0.004,1KG_EAS_AF,TSPEAR
502865,21:45941455:CG>C,NM_144991.2:c.1566+310del,\N,\N,9/11,Benign,\N,intron_variant,0.642,0.0113,1KG_AFR_AF,TSPEAR
502866,21:45941456:G>C,NM_144991.2:c.1566+310C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.18,\N,\N,TSPEAR
502867,21:45941467:T>C,NM_144991.2:c.1566+299A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,1.02,0.0008,1KG_AFR_AF,TSPEAR
502868,21:45941469:TGGA>T,NM_144991.2:c.1566+294_1566+296del,\N,\N,9/11,Benign,\N,intron_variant,5.358,0.0058,1KG_AMR_AF,TSPEAR
502869,21:45941481:T>C,NM_144991.2:c.1566+285A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.509,\N,\N,TSPEAR
502870,21:45941507:C>T,NM_144991.2:c.1566+259G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,4.677,0.001,1KG_EAS_AF,TSPEAR
502871,21:45941513:C>T,NM_144991.2:c.1566+253G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,5.17,\N,\N,TSPEAR
502872,21:45941539:G>A,NM_144991.2:c.1566+227C>T,\N,\N,9/11,Benign,\N,intron_variant,0.755,0.0061,1KG_SAS_AF,TSPEAR
502873,21:45941548:C>T,NM_144991.2:c.1566+218G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.07,0.0014,1KG_AMR_AF,TSPEAR
502874,21:45941550:C>T,NM_144991.2:c.1566+216G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.024,0.001,1KG_EAS_AF,TSPEAR
502875,21:45941556:G>A,NM_144991.2:c.1566+210C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.893,\N,\N,TSPEAR
502876,21:45941581:C>T,NM_144991.2:c.1566+185G>A,\N,\N,9/11,Benign,\N,intron_variant,2.585,0.0083,1KG_AFR_AF,TSPEAR
502877,21:45941591:G>A,NM_144991.2:c.1566+175C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.222,0.0008,1KG_AFR_AF,TSPEAR
502878,21:45941603:G>A,NM_144991.2:c.1566+163C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.063,\N,\N,TSPEAR
502879,21:45941608:G>A,NM_144991.2:c.1566+158C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,2.78,\N,\N,TSPEAR
502880,21:45941610:G>T,NM_144991.2:c.1566+156C>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.219,0.002,1KG_SAS_AF,TSPEAR
502881,21:45941615:A>G,NM_144991.2:c.1566+151T>C,\N,\N,9/11,Unknown significance,\N,intron_variant,3.655,\N,\N,TSPEAR
502882,21:45941624:C>T,NM_144991.2:c.1566+142G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,4.326,0.001,1KG_EAS_AF,TSPEAR
502883,21:45941626:G>A,NM_144991.2:c.1566+140C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.399,0.001,1KG_EUR_AF,TSPEAR
502884,21:45941642:G>A,NM_144991.2:c.1566+124C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.972,\N,\N,TSPEAR
502885,21:45941645:G>A,NM_144991.2:c.1566+121C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.781,0.001,1KG_SAS_AF,TSPEAR
502886,21:45941719:C>T,NM_144991.2:c.1566+47G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,2.323,0.0000155705,EXAC_NFE_AF,TSPEAR
502887,21:45941720:G>A,NM_144991.2:c.1566+46C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.298,0.000265534,EXAC_AMR_AF,TSPEAR
502888,21:45941720:G>T,NM_144991.2:c.1566+46C>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.072,0.0000638081,EXAC_SAS_AF,TSPEAR
502889,21:45941725:G>A,NM_144991.2:c.1566+41C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,1.471,0.000116279,EVS_EA_AF,TSPEAR
502890,21:45941726:G>A,NM_144991.2:c.1566+40C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.267,\N,\N,TSPEAR
502891,21:45941734:T>C,NM_144991.2:c.1566+32A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.851,\N,\N,TSPEAR
502892,21:45941742:C>T,NM_144991.2:c.1566+24G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.427,0.0008,1KG_AFR_AF,TSPEAR
502893,21:45941743:G>A,NM_144991.2:c.1566+23C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.399,0.00162526,EXAC_EAS_AF,TSPEAR
502894,21:45941744:G>A,NM_144991.2:c.1566+22C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,2.626,0.000116279,EVS_EA_AF,TSPEAR
502895,21:45941746:G>T,NM_144991.2:c.1566+20C>A,\N,\N,9/11,Unknown significance,\N,intron_variant,1.859,0.000226963,EVS_AA_AF,TSPEAR
502896,21:45941751:T>C,NM_144991.2:c.1566+15A>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.457,0.0000610836,EXAC_NFE_AF,TSPEAR
502897,21:45941753:C>CG,NM_144991.2:c.1566+12dup,\N,\N,9/11,Unknown significance,\N,intron_variant,\N,0.000694927,EXAC_EAS_AF,TSPEAR
502898,21:45941753:C>T,NM_144991.2:c.1566+13G>A,\N,\N,9/11,Unknown significance,\N,intron_variant,0.804,0.0008,1KG_AFR_AF,TSPEAR
502899,21:45941754:G>A,NM_144991.2:c.1566+12C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,0.002,0.00499319,EVS_AA_AF,TSPEAR
502900,21:45941754:G>C,NM_144991.2:c.1566+12C>G,\N,\N,9/11,Unknown significance,\N,intron_variant,0.002,0.0000987167,EXAC_AFR_AF,TSPEAR
502901,21:45941756:G>A,NM_144991.2:c.1566+10C>T,\N,\N,9/11,Unknown significance,\N,intron_variant,3.609,0.0008,1KG_AFR_AF,TSPEAR
502902,21:45941758:G>A,NM_144991.2:c.1566+8C>T,\N,\N,9/11,Unknown significance,\N,splice_region_variant&intron_variant,0.47,0.0000608125,EXAC_SAS_AF,TSPEAR
502903,21:45941759:G>GT,NM_144991.2:c.1566+6_1566+7insA,\N,\N,9/11,Unknown significance,\N,splice_region_variant&intron_variant,1.664,0.000154847,EXAC_FIN_AF,TSPEAR
502904,21:45941761:C>T,NM_144991.2:c.1566+5G>A,\N,\N,9/11,Unknown significance,\N,splice_region_variant&intron_variant,16.38,0.0022093,EVS_EA_AF,TSPEAR
502905,21:45941766:C>T,NM_144991.2:c.1566G>A,NP_659428.2:p.Pro522=,9/12,\N,Unknown significance,\N,splice_region_variant&synonymous_variant,17.42,0.0008,1KG_AFR_AF,TSPEAR
502906,21:45941767:G>A,NM_144991.2:c.1565C>T,NP_659428.2:p.Pro522Leu,9/12,\N,Likely benign,\N,missense_variant&splice_region_variant,19.65,0.0000867453,EXAC_AMR_AF,TSPEAR
502907,21:45941772:G>C,NM_144991.2:c.1560C>G,NP_659428.2:p.Ser520=,9/12,\N,Unknown significance,\N,synonymous_variant,5.364,0.0008,1KG_AFR_AF,TSPEAR
502908,21:45941776:TG>T,NM_144991.2:c.1555del,NP_659428.2:p.Gln519SerfsTer50,9/12,\N,Unknown significance,\N,frameshift_variant,36,0.000115714,EXAC_EAS_AF,TSPEAR
502909,21:45941780:A>T,NM_144991.2:c.1552T>A,NP_659428.2:p.Phe518Ile,9/12,\N,Unknown significance,\N,missense_variant,26,0.000115687,EXAC_EAS_AF,TSPEAR
502910,21:45941785:TG>T,NM_144991.2:c.1546del,NP_659428.2:p.Gln516SerfsTer53,9/12,\N,Unknown significance,\N,frameshift_variant,35,0.000030217,EXAC_NFE_AF,TSPEAR
502911,21:45941787:G>A,NM_144991.2:c.1545C>T,NP_659428.2:p.Phe515=,9/12,\N,Unknown significance,\N,synonymous_variant,10.78,0.000231428,EXAC_EAS_AF,TSPEAR
502912,21:45941793:G>A,NM_144991.2:c.1539C>T,NP_659428.2:p.Gly513=,9/12,\N,Unknown significance,\N,synonymous_variant,7.819,0.000015093,EXAC_NFE_AF,TSPEAR
502913,21:45941793:G>GC,NM_144991.2:c.1538dup,NP_659428.2:p.Ser514LeufsTer44,9/12,\N,Unknown significance,\N,frameshift_variant,34,0.0000605694,EXAC_SAS_AF,TSPEAR
502914,21:45941796:C>T,NM_144991.2:c.1536G>A,NP_659428.2:p.Leu512=,9/12,\N,Unknown significance,\N,synonymous_variant,10.64,0.0000150916,EXAC_NFE_AF,TSPEAR
502915,21:45941803:C>A,NM_144991.2:c.1529G>T,NP_659428.2:p.Arg510Leu,9/12,\N,Unknown significance,\N,missense_variant,22.7,0.000151378,EXAC_FIN_AF,TSPEAR
502916,21:45941803:C>T,NM_144991.2:c.1529G>A,NP_659428.2:p.Arg510Gln,9/12,\N,Unknown significance,\N,missense_variant,25.1,0.001,1KG_EAS_AF,TSPEAR
502917,21:45941804:G>A,NM_144991.2:c.1528C>T,NP_659428.2:p.Arg510Ter,9/12,\N,Unknown significance,\N,stop_gained,35,0.003,1KG_EUR_AF,TSPEAR
502918,21:45941806:A>G,NM_144991.2:c.1526T>C,NP_659428.2:p.Ile509Thr,9/12,\N,Unknown significance,\N,missense_variant,15.1,0.0000605694,EXAC_SAS_AF,TSPEAR
502919,21:45941808:G>A,NM_144991.2:c.1524C>T,NP_659428.2:p.Tyr508=,9/12,\N,Unknown significance,\N,synonymous_variant,0.236,0.000907853,EVS_AA_AF,TSPEAR
502920,21:45941812:A>AGGTGC,NM_144991.2:c.1515_1519dup,NP_659428.2:p.Leu507ArgfsTer64,9/12,\N,Unknown significance,\N,frameshift_variant,31,\N,\N,TSPEAR
502921,21:45941816:G>A,NM_144991.2:c.1516C>T,NP_659428.2:p.His506Tyr,9/12,\N,Likely benign,\N,missense_variant,0.015,0.00017304,EXAC_AMR_AF,TSPEAR
502922,21:45941817:C>A,NM_144991.2:c.1515G>T,NP_659428.2:p.Ser505=,9/12,\N,Unknown significance,\N,synonymous_variant,9.023,0.000060562,EXAC_SAS_AF,TSPEAR
502923,21:45941817:C>T,NM_144991.2:c.1515G>A,NP_659428.2:p.Ser505=,9/12,\N,Unknown significance,\N,synonymous_variant,7.598,0.00177566,EXAC_NFE_AF,TSPEAR
502924,21:45941818:G>A,NM_144991.2:c.1514C>T,NP_659428.2:p.Ser505Leu,9/12,\N,Unknown significance,\N,missense_variant,26.9,0.0000150489,EXAC_NFE_AF,TSPEAR
502925,21:45941826:CT>C,NM_144991.2:c.1505del,NP_659428.2:p.Lys502ArgfsTer67,9/12,\N,Unknown significance,\N,frameshift_variant,14.84,0.0043,1KG_AMR_AF,TSPEAR
502926,21:45941829:G>A,NM_144991.2:c.1503C>T,NP_659428.2:p.Thr501=,9/12,\N,Unknown significance,\N,synonymous_variant,0.005,0.0000300806,EXAC_NFE_AF,TSPEAR
502927,21:45941832:G>A,NM_144991.2:c.1500C>T,NP_659428.2:p.Ser500=,9/12,\N,Unknown significance,\N,synonymous_variant,1.827,0.000096302,EXAC_AFR_AF,TSPEAR
502928,21:45941838:G>C,NM_144991.2:c.1494C>G,NP_659428.2:p.Gly498=,9/12,\N,Unknown significance,\N,synonymous_variant,0.569,0.000288795,EXAC_AFR_AF,TSPEAR
502929,21:45941839:C>A,NM_144991.2:c.1493G>T,NP_659428.2:p.Gly498Val,9/12,\N,Unknown significance,\N,missense_variant,28.1,0.000288795,EXAC_AFR_AF,TSPEAR
502930,21:45941840:C>T,NM_144991.2:c.1492G>A,NP_659428.2:p.Gly498Ser,9/12,\N,Unknown significance,\N,missense_variant,33,0.000453926,EVS_AA_AF,TSPEAR
502931,21:45941841:G>A,NM_144991.2:c.1491C>T,NP_659428.2:p.Asn497=,9/12,\N,Unknown significance,\N,synonymous_variant,7.649,0.000060562,EXAC_SAS_AF,TSPEAR
502932,21:45941842:T>G,NM_144991.2:c.1490A>C,NP_659428.2:p.Asn497Thr,9/12,\N,Unknown significance,\N,missense_variant,26,0.0000150317,EXAC_NFE_AF,TSPEAR
502933,21:45941848:G>A,NM_144991.2:c.1484C>T,NP_659428.2:p.Thr495Ile,9/12,\N,Unknown significance,\N,missense_variant,24.4,0.000115607,EXAC_EAS_AF,TSPEAR
502934,21:45941857:A>G,NM_144991.2:c.1475T>C,NP_659428.2:p.Val492Ala,9/12,\N,Unknown significance,\N,missense_variant,25.3,0.0000150236,EXAC_NFE_AF,TSPEAR
502935,21:45941859:C>G,NM_144991.2:c.1473G>C,NP_659428.2:p.Val491=,9/12,\N,Unknown significance,\N,synonymous_variant,11.07,0.000060562,EXAC_SAS_AF,TSPEAR
502936,21:45941863:A>T,NM_144991.2:c.1469T>A,NP_659428.2:p.Leu490Gln,9/12,\N,Unknown significance,\N,missense_variant,28.3,0.0000600817,EXAC_NFE_AF,TSPEAR
502937,21:45941865:G>A,NM_144991.2:c.1467C>T,NP_659428.2:p.Phe489=,9/12,\N,Unknown significance,\N,synonymous_variant,11.17,\N,\N,TSPEAR
502938,21:45941866:A>G,NM_144991.2:c.1466T>C,NP_659428.2:p.Phe489Ser,9/12,\N,Unknown significance,\N,missense_variant,32,0.0000150186,EXAC_NFE_AF,TSPEAR
502939,21:45941868:C>G,NM_144991.2:c.1464G>C,NP_659428.2:p.Ser488=,9/12,\N,Unknown significance,\N,synonymous_variant,16.18,0.000226963,EVS_AA_AF,TSPEAR
502940,21:45941868:C>T,NM_144991.2:c.1464G>A,NP_659428.2:p.Ser488=,9/12,\N,Unknown significance,\N,synonymous_variant,19.17,0.001,1KG_SAS_AF,TSPEAR
502941,21:45941871:G>A,NM_144991.2:c.1461C>T,NP_659428.2:p.Tyr487=,9/12,\N,Unknown significance,\N,synonymous_variant,3.398,0.0000300336,EXAC_NFE_AF,TSPEAR
502942,21:45941875:G>A,NM_144991.2:c.1457C>T,NP_659428.2:p.Pro486Leu,9/12,\N,Unknown significance,\N,missense_variant,31,0.0000150141,EXAC_NFE_AF,TSPEAR
502943,21:45941883:A>G,NM_144991.2:c.1449T>C,NP_659428.2:p.Ser483=,9/12,\N,Unknown significance,\N,synonymous_variant,0.068,0.000060562,EXAC_SAS_AF,TSPEAR
502944,21:45941884:C>A,NM_144991.2:c.1448G>T,NP_659428.2:p.Ser483Ile,9/12,\N,Likely benign,\N,missense_variant,19.23,0.0000150105,EXAC_NFE_AF,TSPEAR
502945,21:45941889:G>A,NM_144991.2:c.1443C>T,NP_659428.2:p.Phe481=,9/12,\N,Unknown significance,\N,synonymous_variant,12.1,0.000060562,EXAC_SAS_AF,TSPEAR
502946,21:45941892:C>A,NM_144991.2:c.1440G>T,NP_659428.2:p.Glu480Asp,9/12,\N,Unknown significance,\N,missense_variant,24.4,0.0000961354,EXAC_AFR_AF,TSPEAR
502947,21:45941894:C>T,NM_144991.2:c.1438G>A,NP_659428.2:p.Glu480Lys,9/12,\N,Unknown significance,\N,missense_variant,26.4,0.0000961354,EXAC_AFR_AF,TSPEAR
502948,21:45941900:C>T,NM_144991.2:c.1432G>A,NP_659428.2:p.Asp478Asn,9/12,\N,Unknown significance,\N,missense_variant,34,0.000226963,EVS_AA_AF,TSPEAR
502949,21:45941901:G>A,NM_144991.2:c.1431C>T,NP_659428.2:p.Tyr477=,9/12,\N,Unknown significance,\N,synonymous_variant,5.617,0.00110375,EXAC_OTH_AF,TSPEAR
502950,21:45941907:G>A,NM_144991.2:c.1425C>T,NP_659428.2:p.Gly475=,9/12,\N,Unknown significance,\N,synonymous_variant,6.877,0.00023116,EXAC_EAS_AF,TSPEAR
502951,21:45941909:C>T,NM_144991.2:c.1423G>A,NP_659428.2:p.Gly475Ser,9/12,\N,Unknown significance,\N,missense_variant,28.7,0.00011558,EXAC_EAS_AF,TSPEAR
502952,21:45941910:G>A,NM_144991.2:c.1422C>T,NP_659428.2:p.Ser474=,9/12,\N,Unknown significance,\N,synonymous_variant,3.264,0.000864155,EXAC_AMR_AF,TSPEAR
502953,21:45941910:G>GGAGGT,NM_144991.2:c.1417_1421dup,NP_659428.2:p.Gly475ProfsTer96,9/12,\N,Unknown significance,\N,frameshift_variant,33,0.0000864155,EXAC_AMR_AF,TSPEAR
502954,21:45941918:C>T,NM_144991.2:c.1414G>A,NP_659428.2:p.Ala472Thr,9/12,\N,Likely benign,\N,missense_variant,13.91,0.002,1KG_SAS_AF,TSPEAR
502955,21:45941919:G>A,NM_144991.2:c.1413C>T,NP_659428.2:p.Ile471=,9/12,\N,Unknown significance,\N,synonymous_variant,1.672,0.000116279,EVS_EA_AF,TSPEAR
502956,21:45941922:G>A,NM_144991.2:c.1410C>T,NP_659428.2:p.Thr470=,9/12,\N,Unknown significance,\N,synonymous_variant,8.97,0.0000150101,EXAC_NFE_AF,TSPEAR
502957,21:45941925:CTGGT>C,NM_144991.2:c.1403_1406del,NP_659428.2:p.Asn468ArgfsTer100,9/12,\N,Unknown significance,\N,frameshift_variant,35,0.000015011,EXAC_NFE_AF,TSPEAR
502958,21:45941936:C>G,NM_144991.2:c.1396G>C,NP_659428.2:p.Glu466Gln,9/12,\N,Unknown significance,\N,missense_variant,22.7,0.000121124,EXAC_SAS_AF,TSPEAR
502959,21:45941936:C>T,NM_144991.2:c.1396G>A,NP_659428.2:p.Glu466Lys,9/12,\N,Unknown significance,\N,missense_variant,24.1,0.0014,1KG_AMR_AF,TSPEAR
502960,21:45941937:G>A,NM_144991.2:c.1395C>T,NP_659428.2:p.Phe465=,9/12,\N,Unknown significance,\N,synonymous_variant,11.87,0.0000864304,EXAC_AMR_AF,TSPEAR
502961,21:45941945:G>A,NM_144991.2:c.1387C>T,NP_659428.2:p.Arg463Trp,9/12,\N,Unknown significance,\N,missense_variant,27.3,0.00151194,EXAC_FIN_AF,TSPEAR
502962,21:45941945:G>C,NM_144991.2:c.1387C>G,NP_659428.2:p.Arg463Gly,9/12,\N,Likely benign,\N,missense_variant,12.9,0.0000864155,EXAC_AMR_AF,TSPEAR
502963,21:45941952:C>A,NM_144991.2:c.1380G>T,NP_659428.2:p.Pro460=,9/12,\N,Unknown significance,\N,synonymous_variant,16.36,0.0000150177,EXAC_NFE_AF,TSPEAR
502964,21:45941952:C>T,NM_144991.2:c.1380G>A,NP_659428.2:p.Pro460=,9/12,\N,Unknown significance,\N,synonymous_variant,15.49,0.000151194,EXAC_FIN_AF,TSPEAR
502965,21:45941953:G>T,NM_144991.2:c.1379C>A,NP_659428.2:p.Pro460Gln,9/12,\N,Unknown significance,\N,missense_variant,25.1,0.000151194,EXAC_FIN_AF,TSPEAR
502966,21:45941954:G>A,NM_144991.2:c.1378C>T,NP_659428.2:p.Pro460Ser,9/12,\N,Unknown significance,\N,missense_variant,20.5,0.0000962279,EXAC_AFR_AF,TSPEAR
502967,21:45941960:A>C,NM_144991.2:c.1372T>G,NP_659428.2:p.Trp458Gly,9/12,\N,Unknown significance,\N,missense_variant,26.9,0.0000864304,EXAC_AMR_AF,TSPEAR
502968,21:45941965:T>C,NM_144991.2:c.1367A>G,NP_659428.2:p.Tyr456Cys,9/12,\N,Unknown significance,\N,missense_variant,26,0.000015024,EXAC_NFE_AF,TSPEAR
502969,21:45941967:G>C,NM_144991.2:c.1365C>G,NP_659428.2:p.Ile455Met,9/12,\N,Unknown significance,\N,missense_variant,25.7,0.0000150254,EXAC_NFE_AF,TSPEAR
502970,21:45941968:A>G,NM_144991.2:c.1364T>C,NP_659428.2:p.Ile455Thr,9/12,\N,Unknown significance,\N,missense_variant,26,0.0000300526,EXAC_NFE_AF,TSPEAR
502971,21:45941970:G>A,NM_144991.2:c.1362C>T,NP_659428.2:p.Val454=,9/12,\N,Unknown significance,\N,synonymous_variant,11.9,0.0000150277,EXAC_NFE_AF,TSPEAR
502972,21:45941975:T>C,NM_144991.2:c.1357A>G,NP_659428.2:p.Ser453Gly,9/12,\N,Unknown significance,\N,missense_variant,25.8,0.000115634,EXAC_EAS_AF,TSPEAR
502973,21:45941976:G>T,NM_144991.2:c.1356C>A,NP_659428.2:p.Asp452Glu,9/12,\N,Likely benign,\N,missense_variant,17.77,0.000242277,EXAC_SAS_AF,TSPEAR
502974,21:45941979:G>A,NM_144991.2:c.1353C>T,NP_659428.2:p.Ile451=,9/12,\N,Unknown significance,\N,synonymous_variant,12.85,0.00278619,EXAC_SAS_AF,TSPEAR
502975,21:45941980:ATGT>A,NM_144991.2:c.1349_1351del,NP_659428.2:p.Asn450del,9/12,\N,Unknown significance,\N,inframe_deletion,19.44,\N,\N,TSPEAR
502976,21:45941982:G>A,NM_144991.2:c.1350C>T,NP_659428.2:p.Asn450=,9/12,\N,Unknown significance,\N,synonymous_variant,8.594,0.0000864454,EXAC_AMR_AF,TSPEAR
502977,21:45941988:G>GT,NM_144991.2:c.1343dup,NP_659428.2:p.Asn448LysfsTer110,9/12,\N,Unknown significance,\N,frameshift_variant,\N,\N,\N,TSPEAR
502978,21:45941994:G>A,NM_144991.2:c.1338C>T,NP_659428.2:p.Gly446=,9/12,\N,Unknown significance,\N,splice_region_variant&synonymous_variant,7.503,0.002,1KG_SAS_AF,TSPEAR
502979,21:45941994:G>T,NM_144991.2:c.1338C>A,NP_659428.2:p.Gly446=,9/12,\N,Unknown significance,\N,splice_region_variant&synonymous_variant,6.376,0.0000150457,EXAC_NFE_AF,TSPEAR
502980,21:45941998:G>A,NM_144991.2:c.1337-3C>T,\N,\N,8/11,Unknown significance,\N,splice_region_variant&intron_variant,9.548,0.0000301105,EXAC_NFE_AF,TSPEAR
502981,21:45942002:C>G,NM_144991.2:c.1337-7G>C,\N,\N,8/11,Unknown significance,\N,splice_region_variant&intron_variant,4.869,0.000181884,EXAC_SAS_AF,TSPEAR
502982,21:45942011:T>C,NM_144991.2:c.1337-16A>G,\N,\N,8/11,Unknown significance,\N,intron_variant,1.9,0.0000865202,EXAC_AMR_AF,TSPEAR
502983,21:45942012:G>C,NM_144991.2:c.1337-17C>G,\N,\N,8/11,Unknown significance,\N,intron_variant,1.649,\N,\N,TSPEAR
502984,21:45942014:G>A,NM_144991.2:c.1337-19C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,4.891,0.0000150775,EXAC_NFE_AF,TSPEAR
502985,21:45942017:G>T,NM_144991.2:c.1337-22C>A,\N,\N,8/11,Unknown significance,\N,intron_variant,3.739,0.001,1KG_SAS_AF,TSPEAR
502986,21:45942019:G>A,NM_144991.2:c.1337-24C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,2.987,0.0000150898,EXAC_NFE_AF,TSPEAR
502987,21:45942020:G>C,NM_144991.2:c.1337-25C>G,\N,\N,8/11,Unknown significance,\N,intron_variant,1.767,0.000116279,EVS_EA_AF,TSPEAR
502988,21:45942021:G>A,NM_144991.2:c.1337-26C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,1.187,0.0008,1KG_AFR_AF,TSPEAR
502989,21:45942023:A>G,NM_144991.2:c.1337-28T>C,\N,\N,8/11,Unknown significance,\N,intron_variant,3.354,0.0000969744,EXAC_AFR_AF,TSPEAR
502990,21:45942026:G>A,NM_144991.2:c.1337-31C>T,\N,\N,8/11,Benign,\N,intron_variant,4.255,0.0179,1KG_EUR_AF,TSPEAR
502991,21:45942031:A>G,NM_144991.2:c.1337-36T>C,\N,\N,8/11,Unknown significance,\N,intron_variant,2.157,0.000453926,EVS_AA_AF,TSPEAR
502992,21:45942032:G>A,NM_144991.2:c.1337-37C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,1.799,0.0000151208,EXAC_NFE_AF,TSPEAR
502993,21:45942033:A>T,NM_144991.2:c.1337-38T>A,\N,\N,8/11,Unknown significance,\N,intron_variant,1.019,\N,\N,TSPEAR
502994,21:45942037:C>A,NM_144991.2:c.1337-42G>T,\N,\N,8/11,Unknown significance,\N,intron_variant,5.341,0.0000866852,EXAC_AMR_AF,TSPEAR
502995,21:45942059:C>T,NM_144991.2:c.1337-64G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,1.976,0.001,1KG_EAS_AF,TSPEAR
502996,21:45942060:G>A,NM_144991.2:c.1337-65C>T,\N,\N,8/11,Benign,\N,intron_variant,0.51,0.0363,1KG_AFR_AF,TSPEAR
502997,21:45942088:C>T,NM_144991.2:c.1337-93G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,5.375,0.0008,1KG_AFR_AF,TSPEAR
502998,21:45942090:G>A,NM_144991.2:c.1337-95C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,1.802,0.001,1KG_EUR_AF,TSPEAR
502999,21:45942095:C>A,NM_144991.2:c.1337-100G>T,\N,\N,8/11,Unknown significance,\N,intron_variant,2.534,0.001,1KG_EUR_AF,TSPEAR
503000,21:45942097:G>A,NM_144991.2:c.1337-102C>T,\N,\N,8/11,Benign,\N,intron_variant,0.212,0.0061,1KG_AFR_AF,TSPEAR
503001,21:45942106:C>T,NM_144991.2:c.1337-111G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,0.371,0.0008,1KG_AFR_AF,TSPEAR
503002,21:45942107:G>A,NM_144991.2:c.1337-112C>T,\N,\N,8/11,Benign,\N,intron_variant,0.358,0.1649,1KG_AFR_AF,TSPEAR
503003,21:45942110:G>C,NM_144991.2:c.1337-115C>G,\N,\N,8/11,Unknown significance,\N,intron_variant,0.561,0.0023,1KG_AFR_AF,TSPEAR
503004,21:45942110:GA>CG,NM_144991.2:c.1337-116_1337-115delinsCG,\N,\N,8/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503005,21:45942111:A>G,NM_144991.2:c.1337-116T>C,\N,\N,8/11,Benign,\N,intron_variant,3.264,0.9355,1KG_EAS_AF,TSPEAR
503006,21:45942115:G>A,NM_144991.2:c.1337-120C>T,\N,\N,8/11,Benign,\N,intron_variant,1.775,0.1657,1KG_AFR_AF,TSPEAR
503007,21:45942123:G>A,NM_144991.2:c.1337-128C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,2.642,0.0008,1KG_AFR_AF,TSPEAR
503008,21:45942147:G>A,NM_144991.2:c.1337-152C>T,\N,\N,8/11,Benign,\N,intron_variant,3.042,0.0083,1KG_AFR_AF,TSPEAR
503009,21:45942155:C>T,NM_144991.2:c.1337-160G>A,\N,\N,8/11,Benign,\N,intron_variant,1.857,0.0189,1KG_EUR_AF,TSPEAR
503010,21:45942181:C>T,NM_144991.2:c.1337-186G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,4.919,0.0008,1KG_AFR_AF,TSPEAR
503011,21:45942188:C>A,NM_144991.2:c.1337-193G>T,\N,\N,8/11,Unknown significance,\N,intron_variant,2.98,0.001,1KG_SAS_AF,TSPEAR
503012,21:45942193:A>G,NM_144991.2:c.1337-198T>C,\N,\N,8/11,Unknown significance,\N,intron_variant,2.508,\N,\N,TSPEAR
503013,21:45942216:A>G,NM_144991.2:c.1337-221T>C,\N,\N,8/11,Benign,\N,intron_variant,0.343,0.0051,1KG_SAS_AF,TSPEAR
503014,21:45942234:C>T,NM_144991.2:c.1337-239G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,1.804,0.001,1KG_EAS_AF|1KG_SAS_AF,TSPEAR
503015,21:45942240:T>C,NM_144991.2:c.1337-245A>G,\N,\N,8/11,Benign,\N,intron_variant,0.11,0.3555,1KG_AFR_AF,TSPEAR
503016,21:45942241:G>C,NM_144991.2:c.1337-246C>G,\N,\N,8/11,Unknown significance,\N,intron_variant,0.125,0.001,1KG_SAS_AF,TSPEAR
503017,21:45942265:C>T,NM_144991.2:c.1337-270G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,4.399,\N,\N,TSPEAR
503018,21:45942270:C>T,NM_144991.2:c.1337-275G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,0.19,0.001,1KG_SAS_AF,TSPEAR
503019,21:45942282:G>T,NM_144991.2:c.1337-287C>A,\N,\N,8/11,Unknown significance,\N,intron_variant,0.052,0.002,1KG_EAS_AF,TSPEAR
503020,21:45942290:C>T,NM_144991.2:c.1337-295G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,2.442,\N,\N,TSPEAR
503021,21:45942293:C>T,NM_144991.2:c.1337-298G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,0.735,0.0038,1KG_AFR_AF,TSPEAR
503022,21:45942307:G>A,NM_144991.2:c.1337-312C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,1.376,0.002,1KG_SAS_AF,TSPEAR
503023,21:45942315:C>T,NM_144991.2:c.1337-320G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,1.361,0.001,1KG_EAS_AF,TSPEAR
503024,21:45942318:C>T,NM_144991.2:c.1337-323G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,4.651,0.001,1KG_EUR_AF,TSPEAR
503025,21:45942325:G>T,NM_144991.2:c.1337-330C>A,\N,\N,8/11,Benign,\N,intron_variant,0.766,0.0197,1KG_AFR_AF,TSPEAR
503026,21:45942336:G>A,NM_144991.2:c.1337-341C>T,\N,\N,8/11,Benign,\N,intron_variant,6.09,0.0113,1KG_AFR_AF,TSPEAR
503027,21:45942351:C>T,NM_144991.2:c.1337-356G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,3.563,0.004,1KG_EUR_AF,TSPEAR
503028,21:45942352:G>A,NM_144991.2:c.1337-357C>T,\N,\N,8/11,Benign,\N,intron_variant,1.35,0.0113,1KG_AFR_AF,TSPEAR
503029,21:45942369:C>T,NM_144991.2:c.1337-374G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,0.149,0.001,1KG_EUR_AF,TSPEAR
503030,21:45942370:G>A,NM_144991.2:c.1337-375C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,1.832,0.002,1KG_EUR_AF,TSPEAR
503031,21:45942393:G>A,NM_144991.2:c.1337-398C>T,\N,\N,8/11,Benign,\N,intron_variant,2.825,0.1657,1KG_AFR_AF,TSPEAR
503032,21:45942404:A>G,NM_144991.2:c.1337-409T>C,\N,\N,8/11,Unknown significance,\N,intron_variant,0.378,\N,\N,TSPEAR
503033,21:45942412:G>A,NM_144991.2:c.1337-417C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,2.874,0.0038,1KG_AFR_AF,TSPEAR
503034,21:45942423:CAG>C,NM_144991.2:c.1337-430_1337-429del,\N,\N,8/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503035,21:45942441:T>C,NM_144991.2:c.1337-446A>G,\N,\N,8/11,Benign,\N,intron_variant,2.682,0.0129,1KG_AFR_AF,TSPEAR
503036,21:45942471:T>C,NM_144991.2:c.1337-476A>G,\N,\N,8/11,Benign,\N,intron_variant,0.462,0.0098,1KG_AFR_AF,TSPEAR
503037,21:45942480:C>T,NM_144991.2:c.1337-485G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,3.767,\N,\N,TSPEAR
503038,21:45942481:G>A,NM_144991.2:c.1337-486C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,2.529,0.001,1KG_EUR_AF,TSPEAR
503039,21:45942486:G>T,NM_144991.2:c.1337-491C>A,\N,\N,8/11,Unknown significance,\N,intron_variant,1.478,\N,\N,TSPEAR
503040,21:45942506:G>A,NM_144991.2:c.1337-511C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,1.032,0.0008,1KG_AFR_AF,TSPEAR
503041,21:45942527:G>A,NM_144991.2:c.1337-532C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,2.272,0.001,1KG_EAS_AF,TSPEAR
503042,21:45942529:A>G,NM_144991.2:c.1337-534T>C,\N,\N,8/11,Benign,\N,intron_variant,1.894,0.0083,1KG_AFR_AF,TSPEAR
503043,21:45942531:G>A,NM_144991.2:c.1337-536C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,3.202,0.001,1KG_EAS_AF,TSPEAR
503044,21:45942545:C>T,NM_144991.2:c.1337-550G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,6.351,0.0008,1KG_AFR_AF,TSPEAR
503045,21:45942546:G>A,NM_144991.2:c.1337-551C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,0.659,\N,\N,TSPEAR
503046,21:45942564:G>T,NM_144991.2:c.1337-569C>A,\N,\N,8/11,Unknown significance,\N,intron_variant,0.521,0.0008,1KG_AFR_AF,TSPEAR
503047,21:45942572:A>C,NM_144991.2:c.1337-577T>G,\N,\N,8/11,Unknown significance,\N,intron_variant,0.068,0.001,1KG_EUR_AF,TSPEAR
503048,21:45942580:TC>T,NM_144991.2:c.1337-586del,\N,\N,8/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503049,21:45942612:G>C,NM_144991.2:c.1337-617C>G,\N,\N,8/11,Unknown significance,\N,intron_variant,0.241,0.0014,1KG_AMR_AF,TSPEAR
503050,21:45942613:T>C,NM_144991.2:c.1337-618A>G,\N,\N,8/11,Unknown significance,\N,intron_variant,0.227,0.001,1KG_EAS_AF,TSPEAR
503051,21:45942618:G>A,NM_144991.2:c.1337-623C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,2.046,\N,\N,TSPEAR
503052,21:45942630:C>T,NM_144991.2:c.1337-635G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,0.031,0.001,1KG_SAS_AF,TSPEAR
503053,21:45942633:G>A,NM_144991.2:c.1337-638C>T,\N,\N,8/11,Benign,\N,intron_variant,1.825,0.1687,1KG_AFR_AF,TSPEAR
503054,21:45942647:C>T,NM_144991.2:c.1337-652G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,5.613,\N,\N,TSPEAR
503055,21:45942673:T>C,NM_144991.2:c.1337-678A>G,\N,\N,8/11,Unknown significance,\N,intron_variant,0.783,0.002,1KG_SAS_AF,TSPEAR
503056,21:45942736:C>T,NM_144991.2:c.1337-741G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,4.028,0.0014,1KG_AMR_AF,TSPEAR
503057,21:45942745:T>C,NM_144991.2:c.1337-750A>G,\N,\N,8/11,Benign,\N,intron_variant,0.052,0.3517,1KG_AFR_AF,TSPEAR
503058,21:45942844:T>TAGTC,NM_144991.2:c.1337-853_1337-850dup,\N,\N,8/11,Unknown significance,\N,intron_variant,4.798,0.0038,1KG_AFR_AF,TSPEAR
503059,21:45942844:TAGTC>T,NM_144991.2:c.1337-853_1337-850del,\N,\N,8/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503060,21:45942860:TGTC>T,NM_144991.2:c.1337-868_1337-866del,\N,\N,8/11,Unknown significance,\N,intron_variant,\N,0.0038,1KG_AFR_AF,TSPEAR
503061,21:45942862:T>C,NM_144991.2:c.1337-867A>G,\N,\N,8/11,Unknown significance,\N,intron_variant,3.906,\N,\N,TSPEAR
503062,21:45942871:C>T,NM_144991.2:c.1337-876G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,0.301,0.001,1KG_EUR_AF,TSPEAR
503063,21:45942875:TAGTC>T,NM_144991.2:c.1337-884_1337-881del,\N,\N,8/11,Unknown significance,\N,intron_variant,5.33,\N,\N,TSPEAR
503064,21:45942886:C>G,NM_144991.2:c.1337-891G>C,\N,\N,8/11,Benign,\N,intron_variant,1.478,0.0204,1KG_AFR_AF,TSPEAR
503065,21:45942889:T>A,NM_144991.2:c.1337-894A>T,\N,\N,8/11,Benign,\N,intron_variant,4.345,0.0295,1KG_AFR_AF,TSPEAR
503066,21:45942914:TAGTC>T,NM_144991.2:c.1337-923_1337-920del,\N,\N,8/11,Benign,\N,intron_variant,6.03,0.0072,1KG_SAS_AF,TSPEAR
503067,21:45942954:CAGTT>C,NM_144991.2:c.1337-963_1337-960del,\N,\N,8/11,Benign,\N,intron_variant,3.64,0.1657,1KG_AFR_AF,TSPEAR
503068,21:45942958:T>C,NM_144991.2:c.1337-963A>G,\N,\N,8/11,Unknown significance,\N,intron_variant,0.006,\N,\N,TSPEAR
503069,21:45942966:C>T,NM_144991.2:c.1337-971G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,1.986,0.0041,1KG_SAS_AF,TSPEAR
503070,21:45942969:T>C,NM_144991.2:c.1337-974A>G,\N,\N,8/11,Benign,\N,intron_variant,0.074,0.0567,1KG_AFR_AF,TSPEAR
503071,21:45942985:C>T,NM_144991.2:c.1337-990G>A,\N,\N,8/11,Benign,\N,intron_variant,0.01,0.1657,1KG_AFR_AF,TSPEAR
503072,21:45942992:G>T,NM_144991.2:c.1337-997C>A,\N,\N,8/11,Unknown significance,\N,intron_variant,0.482,0.002,1KG_EUR_AF,TSPEAR
503073,21:45943043:G>A,NM_144991.2:c.1337-1048C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,0.113,\N,\N,TSPEAR
503074,21:45943050:C>T,NM_144991.2:c.1337-1055G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,1.643,0.0014,1KG_AMR_AF,TSPEAR
503075,21:45943053:T>C,NM_144991.2:c.1337-1058A>G,\N,\N,8/11,Benign,\N,intron_variant,0.872,0.0303,1KG_AFR_AF,TSPEAR
503076,21:45943069:C>T,NM_144991.2:c.1337-1074G>A,\N,\N,8/11,Benign,\N,intron_variant,1.562,0.1619,1KG_AFR_AF,TSPEAR
503077,21:45943082:G>T,NM_144991.2:c.1337-1087C>A,\N,\N,8/11,Unknown significance,\N,intron_variant,0.238,0.0014,1KG_AMR_AF,TSPEAR
503078,21:45943085:G>T,NM_144991.2:c.1337-1090C>A,\N,\N,8/11,Unknown significance,\N,intron_variant,0.189,0.0008,1KG_AFR_AF,TSPEAR
503079,21:45943087:A>T,NM_144991.2:c.1337-1092T>A,\N,\N,8/11,Unknown significance,\N,intron_variant,0.537,0.0008,1KG_AFR_AF,TSPEAR
503080,21:45943131:A>G,NM_144991.2:c.1337-1136T>C,\N,\N,8/11,Unknown significance,\N,intron_variant,1.355,0.0014,1KG_AMR_AF,TSPEAR
503081,21:45943156:A>G,NM_144991.2:c.1337-1161T>C,\N,\N,8/11,Benign,\N,intron_variant,5.043,0.0106,1KG_AFR_AF,TSPEAR
503082,21:45943172:TTCAG>T,NM_144991.2:c.1337-1181_1337-1178del,\N,\N,8/11,Unknown significance,\N,intron_variant,\N,0.0029,1KG_AMR_AF,TSPEAR
503083,21:45943180:G>A,NM_144991.2:c.1337-1185C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,2.968,0.002,1KG_EAS_AF,TSPEAR
503084,21:45943188:G>A,NM_144991.2:c.1337-1193C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,2.576,0.001,1KG_EAS_AF,TSPEAR
503085,21:45943190:T>C,NM_144991.2:c.1337-1195A>G,\N,\N,8/11,Benign,\N,intron_variant,1.879,0.0091,1KG_AFR_AF,TSPEAR
503086,21:45943190:TTGTC>T,NM_144991.2:c.1337-1199_1337-1196del,\N,\N,8/11,Benign,\N,intron_variant,2.461,0.0121,1KG_AFR_AF,TSPEAR
503087,21:45943191:T>A,NM_144991.2:c.1337-1196A>T,\N,\N,8/11,Benign,\N,intron_variant,4.61,0.0091,1KG_AFR_AF,TSPEAR
503088,21:45943191:TGTCA>T,NM_144991.2:c.1337-1200_1337-1197del,\N,\N,8/11,Unknown significance,\N,intron_variant,5.317,\N,\N,TSPEAR
503089,21:45943194:C>T,NM_144991.2:c.1337-1199G>A,\N,\N,8/11,Benign,\N,intron_variant,0.566,0.0091,1KG_AFR_AF,TSPEAR
503090,21:45943195:A>T,NM_144991.2:c.1337-1200T>A,\N,\N,8/11,Benign,\N,intron_variant,1.348,0.0855,1KG_AFR_AF,TSPEAR
503091,21:45943205:G>A,NM_144991.2:c.1337-1210C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,2.279,\N,\N,TSPEAR
503092,21:45943231:G>A,NM_144991.2:c.1337-1236C>T,\N,\N,8/11,Benign,\N,intron_variant,2.07,0.1127,1KG_AFR_AF,TSPEAR
503093,21:45943263:C>T,NM_144991.2:c.1337-1268G>A,\N,\N,8/11,Benign,\N,intron_variant,0.531,0.0068,1KG_AFR_AF,TSPEAR
503094,21:45943275:CAGTT>C,NM_144991.2:c.1337-1284_1337-1281del,\N,\N,8/11,Unknown significance,\N,intron_variant,7.806,\N,\N,TSPEAR
503095,21:45943290:TAAGTC>T,NM_144991.2:c.1337-1300_1337-1296del,\N,\N,8/11,Unknown significance,\N,intron_variant,11.04,0.003,1KG_EUR_AF,TSPEAR
503096,21:45943295:C>A,NM_144991.2:c.1337-1300G>T,\N,\N,8/11,Unknown significance,\N,intron_variant,8.742,\N,\N,TSPEAR
503097,21:45943299:TAGTC>T,NM_144991.2:c.1337-1308_1337-1305del,\N,\N,8/11,Benign,\N,intron_variant,8.956,0.0068,1KG_AFR_AF,TSPEAR
503098,21:45943311:TAGTC>T,NM_144991.2:c.1337-1320_1337-1317del,\N,\N,8/11,Unknown significance,\N,intron_variant,\N,0.001,1KG_EAS_AF|1KG_SAS_AF,TSPEAR
503099,21:45943323:CAGTT>C,NM_144991.2:c.1337-1332_1337-1329del,\N,\N,8/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503100,21:45943334:T>C,NM_144991.2:c.1337-1339A>G,\N,\N,8/11,Unknown significance,\N,intron_variant,1.916,0.001,1KG_EAS_AF,TSPEAR
503101,21:45943343:TAATC>T,NM_144991.2:c.1337-1352_1337-1349del,\N,\N,8/11,Benign,\N,intron_variant,5.462,0.0166,1KG_AFR_AF,TSPEAR
503102,21:45943345:ATCAG>A,NM_144991.2:c.1337-1354_1337-1351del,\N,\N,8/11,Unknown significance,\N,intron_variant,5.53,\N,\N,TSPEAR
503103,21:45943347:C>T,NM_144991.2:c.1337-1352G>A,\N,\N,8/11,Benign,\N,intron_variant,3.681,0.0106,1KG_AFR_AF,TSPEAR
503104,21:45943362:T>C,NM_144991.2:c.1337-1367A>G,\N,\N,8/11,Unknown significance,\N,intron_variant,3.071,0.001,1KG_EAS_AF,TSPEAR
503105,21:45943395:CGTCA>C,NM_144991.2:c.1337-1404_1337-1401del,\N,\N,8/11,Unknown significance,\N,intron_variant,9.028,\N,\N,TSPEAR
503106,21:45943396:G>A,NM_144991.2:c.1337-1401C>T,\N,\N,8/11,Benign,\N,intron_variant,5.994,0.0113,1KG_AFR_AF,TSPEAR
503107,21:45943421:C>A,NM_144991.2:c.1337-1426G>T,\N,\N,8/11,Unknown significance,\N,intron_variant,5.785,0.001,1KG_EUR_AF,TSPEAR
503108,21:45943430:GGTCA>G,NM_144991.2:c.1337-1439_1337-1436del,\N,\N,8/11,Unknown significance,\N,intron_variant,7.729,0.003,1KG_EUR_AF,TSPEAR
503109,21:45943441:A>C,NM_144991.2:c.1337-1446T>G,\N,\N,8/11,Unknown significance,\N,intron_variant,3.522,\N,\N,TSPEAR
503110,21:45943441:AAGTC>A,NM_144991.2:c.1337-1450_1337-1447del,\N,\N,8/11,Unknown significance,\N,intron_variant,3.839,0.002,1KG_EAS_AF,TSPEAR
503111,21:45943449:CAGTT>C,NM_144991.2:c.1337-1458_1337-1455del,\N,\N,8/11,Unknown significance,\N,intron_variant,6.552,\N,\N,TSPEAR
503112,21:45943458:CGTCA>C,NM_144991.2:c.1337-1467_1337-1464del,\N,\N,8/11,Benign,\N,intron_variant,3.723,0.005,1KG_EUR_AF,TSPEAR
503113,21:45943459:G>A,NM_144991.2:c.1337-1464C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,1.126,0.0023,1KG_AFR_AF,TSPEAR
503114,21:45943508:TAATC>T,NM_144991.2:c.1337-1517_1337-1514del,\N,\N,8/11,Benign,\N,intron_variant,9.465,0.0179,1KG_EUR_AF,TSPEAR
503115,21:45943560:G>C,NM_144991.2:c.1337-1565C>G,\N,\N,8/11,Benign,\N,intron_variant,2.526,0.1649,1KG_AFR_AF,TSPEAR
503116,21:45943571:G>A,NM_144991.2:c.1337-1576C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,0.284,0.0014,1KG_AMR_AF,TSPEAR
503117,21:45943575:G>A,NM_144991.2:c.1337-1580C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,2.631,0.0008,1KG_AFR_AF,TSPEAR
503118,21:45943580:G>A,NM_144991.2:c.1337-1585C>T,\N,\N,8/11,Benign,\N,intron_variant,0.421,0.0106,1KG_AFR_AF,TSPEAR
503119,21:45943664:TAGTC>T,NM_144991.2:c.1337-1673_1337-1670del,\N,\N,8/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503120,21:45943676:T>TAGTC,NM_144991.2:c.1337-1685_1337-1682dup,\N,\N,8/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503121,21:45943676:TAGTC>T,NM_144991.2:c.1337-1685_1337-1682del,\N,\N,8/11,Benign,\N,intron_variant,6.191,0.236,1KG_AFR_AF,TSPEAR
503122,21:45943685:A>C,NM_144991.2:c.1337-1690T>G,\N,\N,8/11,Unknown significance,\N,intron_variant,0.687,\N,\N,TSPEAR
503123,21:45943695:T>C,NM_144991.2:c.1337-1700A>G,\N,\N,8/11,Unknown significance,\N,intron_variant,1.286,0.001,1KG_EUR_AF,TSPEAR
503124,21:45943700:CAGTT>C,NM_144991.2:c.1337-1709_1337-1706del,\N,\N,8/11,Unknown significance,\N,intron_variant,3.967,\N,\N,TSPEAR
503125,21:45943704:T>C,NM_144991.2:c.1337-1709A>G,\N,\N,8/11,Benign,\N,intron_variant,0.12,0.098,1KG_AMR_AF,TSPEAR
503126,21:45943708:C>G,NM_144991.2:c.1337-1713G>C,\N,\N,8/11,Unknown significance,\N,intron_variant,0.158,0.001,1KG_EAS_AF,TSPEAR
503127,21:45943722:G>A,NM_144991.2:c.1337-1727C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,6.149,\N,\N,TSPEAR
503128,21:45943751:G>A,NM_144991.2:c.1337-1756C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,3.166,0.001,1KG_EAS_AF,TSPEAR
503129,21:45943757:G>T,NM_144991.2:c.1337-1762C>A,\N,\N,8/11,Unknown significance,\N,intron_variant,0.962,0.0008,1KG_AFR_AF,TSPEAR
503130,21:45943790:G>A,NM_144991.2:c.1336+1746C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,0.162,0.002,1KG_EAS_AF,TSPEAR
503131,21:45943795:TTGTC>T,NM_144991.2:c.1336+1737_1336+1740del,\N,\N,8/11,Benign,\N,intron_variant,1.78,0.0567,1KG_AFR_AF,TSPEAR
503132,21:45943796:T>A,NM_144991.2:c.1336+1740A>T,\N,\N,8/11,Unknown significance,\N,intron_variant,0.374,\N,\N,TSPEAR
503133,21:45943858:G>T,NM_144991.2:c.1336+1678C>A,\N,\N,8/11,Benign,\N,intron_variant,0.018,0.0325,1KG_AFR_AF,TSPEAR
503134,21:45943893:T>G,NM_144991.2:c.1336+1643A>C,\N,\N,8/11,Unknown significance,\N,intron_variant,2.814,0.001,1KG_SAS_AF,TSPEAR
503135,21:45943900:T>G,NM_144991.2:c.1336+1636A>C,\N,\N,8/11,Unknown significance,\N,intron_variant,2.088,0.0031,1KG_SAS_AF,TSPEAR
503136,21:45943901:C>T,NM_144991.2:c.1336+1635G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,2.239,0.0031,1KG_SAS_AF,TSPEAR
503137,21:45943902:AGTCAGGTAGTTAGTCAGTT>A,NM_144991.2:c.1336+1615_1336+1633del,\N,\N,8/11,Unknown significance,\N,intron_variant,5.779,\N,\N,TSPEAR
503138,21:45943908:GTAGT>G,NM_144991.2:c.1336+1624_1336+1627del,\N,\N,8/11,Unknown significance,\N,intron_variant,4.433,0.002,1KG_EUR_AF,TSPEAR
503139,21:45943909:T>G,NM_144991.2:c.1336+1627A>C,\N,\N,8/11,Unknown significance,\N,intron_variant,3.137,\N,\N,TSPEAR
503140,21:45943913:T>C,NM_144991.2:c.1336+1623A>G,\N,\N,8/11,Unknown significance,\N,intron_variant,0.095,0.003,1KG_AFR_AF,TSPEAR
503141,21:45943915:G>C,NM_144991.2:c.1336+1621C>G,\N,\N,8/11,Unknown significance,\N,intron_variant,0.478,0.003,1KG_AFR_AF,TSPEAR
503142,21:45943930:GTCAC>G,NM_144991.2:c.1336+1602_1336+1605del,\N,\N,8/11,Benign,\N,intron_variant,7.664,0.0092,1KG_SAS_AF,TSPEAR
503143,21:45943934:C>G,NM_144991.2:c.1336+1602G>C,\N,\N,8/11,Benign,\N,intron_variant,5.369,0.0051,1KG_SAS_AF,TSPEAR
503144,21:45943987:CAGGT>C,NM_144991.2:c.1336+1545_1336+1548del,\N,\N,8/11,Benign,\N,intron_variant,6.392,0.0061,1KG_AFR_AF,TSPEAR
503145,21:45943991:TAGTC>T,NM_144991.2:c.1336+1541_1336+1544del,\N,\N,8/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503146,21:45943998:T>A,NM_144991.2:c.1336+1538A>T,\N,\N,8/11,Benign,\N,intron_variant,0.935,0.0068,1KG_AFR_AF,TSPEAR
503147,21:45943999:C>T,NM_144991.2:c.1336+1537G>A,\N,\N,8/11,Benign,\N,intron_variant,0.328,0.0068,1KG_AFR_AF,TSPEAR
503148,21:45944002:A>ATAGT,NM_144991.2:c.1336+1530_1336+1533dup,\N,\N,8/11,Unknown significance,\N,intron_variant,0.04,\N,\N,TSPEAR
503149,21:45944002:A>T,NM_144991.2:c.1336+1534T>A,\N,\N,8/11,Benign,\N,intron_variant,0.003,0.0068,1KG_AFR_AF,TSPEAR
503150,21:45944003:TAGTC>T,NM_144991.2:c.1336+1529_1336+1532del,\N,\N,8/11,Benign,\N,intron_variant,\N,0.0266,1KG_SAS_AF,TSPEAR
503151,21:45944007:C>T,NM_144991.2:c.1336+1529G>A,\N,\N,8/11,Benign,\N,intron_variant,2.265,0.1846,1KG_AFR_AF,TSPEAR
503152,21:45944008:A>T,NM_144991.2:c.1336+1528T>A,\N,\N,8/11,Unknown significance,\N,intron_variant,0.811,0.0008,1KG_AFR_AF,TSPEAR
503153,21:45944014:TCAGT>C,NM_144991.2:c.1336+1518_1336+1522delinsG,\N,\N,8/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503154,21:45944018:T>A,NM_144991.2:c.1336+1518A>T,\N,\N,8/11,Unknown significance,\N,intron_variant,6.661,\N,\N,TSPEAR
503155,21:45944018:T>C,NM_144991.2:c.1336+1518A>G,\N,\N,8/11,Benign,\N,intron_variant,2.165,0.1649,1KG_AFR_AF,TSPEAR
503156,21:45944018:T>G,NM_144991.2:c.1336+1518A>C,\N,\N,8/11,Unknown significance,\N,intron_variant,4.066,\N,\N,TSPEAR
503157,21:45944023:TAGTC>T,NM_144991.2:c.1336+1509_1336+1512del,\N,\N,8/11,Unknown significance,\N,intron_variant,7.66,\N,\N,TSPEAR
503158,21:45944030:T>C,NM_144991.2:c.1336+1506A>G,\N,\N,8/11,Benign,\N,intron_variant,5.877,0.0184,1KG_SAS_AF,TSPEAR
503159,21:45944033:G>C,NM_144991.2:c.1336+1503C>G,\N,\N,8/11,Unknown significance,\N,intron_variant,5.325,0.0008,1KG_AFR_AF,TSPEAR
503160,21:45944062:TCAGA>T,NM_144991.2:c.1336+1470_1336+1473del,\N,\N,8/11,Benign,\N,intron_variant,8.358,0.0051,1KG_SAS_AF,TSPEAR
503161,21:45944066:ACAGT>A,NM_144991.2:c.1336+1466_1336+1469del,\N,\N,8/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503162,21:45944097:ATCAGTCAG>A,NM_144991.2:c.1336+1431_1336+1438del,\N,\N,8/11,Unknown significance,\N,intron_variant,10.36,\N,\N,TSPEAR
503163,21:45944106:T>C,NM_144991.2:c.1336+1430A>G,\N,\N,8/11,Unknown significance,\N,intron_variant,9.319,\N,\N,TSPEAR
503164,21:45944134:T>C,NM_144991.2:c.1336+1402A>G,\N,\N,8/11,Unknown significance,\N,intron_variant,12.22,0.002,1KG_EUR_AF,TSPEAR
503165,21:45944134:T>TCAGC,NM_144991.2:c.1336+1398_1336+1401dup,\N,\N,8/11,Unknown significance,\N,intron_variant,\N,0.0041,1KG_SAS_AF,TSPEAR
503166,21:45944146:C>T,NM_144991.2:c.1336+1390G>A,\N,\N,8/11,Benign,\N,intron_variant,12.47,0.1407,1KG_AFR_AF,TSPEAR
503167,21:45944150:C>A,NM_144991.2:c.1336+1386G>T,\N,\N,8/11,Unknown significance,\N,intron_variant,12.87,\N,\N,TSPEAR
503168,21:45944169:A>G,NM_144991.2:c.1336+1367T>C,\N,\N,8/11,Unknown significance,\N,intron_variant,12.68,0.001,1KG_EUR_AF,TSPEAR
503169,21:45944184:A>G,NM_144991.2:c.1336+1352T>C,\N,\N,8/11,Unknown significance,\N,intron_variant,10.52,0.004,1KG_EUR_AF,TSPEAR
503170,21:45944203:T>C,NM_144991.2:c.1336+1333A>G,\N,\N,8/11,Unknown significance,\N,intron_variant,0.277,0.001,1KG_EAS_AF,TSPEAR
503171,21:45944246:G>A,NM_144991.2:c.1336+1290C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,2.575,0.001,1KG_SAS_AF,TSPEAR
503172,21:45944271:T>C,NM_144991.2:c.1336+1265A>G,\N,\N,8/11,Unknown significance,\N,intron_variant,0.011,0.003,1KG_AFR_AF,TSPEAR
503173,21:45944298:T>C,NM_144991.2:c.1336+1238A>G,\N,\N,8/11,Benign,\N,intron_variant,2.227,0.0749,1KG_AFR_AF,TSPEAR
503174,21:45944307:C>T,NM_144991.2:c.1336+1229G>A,\N,\N,8/11,Benign,\N,intron_variant,2.322,0.3064,1KG_AFR_AF,TSPEAR
503175,21:45944323:CAGTT>C,NM_144991.2:c.1336+1209_1336+1212del,\N,\N,8/11,Benign,\N,intron_variant,4.125,0.0129,1KG_EAS_AF,TSPEAR
503176,21:45944331:T>C,NM_144991.2:c.1336+1205A>G,\N,\N,8/11,Unknown significance,\N,intron_variant,0.011,0.001,1KG_EUR_AF|1KG_SAS_AF,TSPEAR
503177,21:45944370:GTAGT>G,NM_144991.2:c.1336+1162_1336+1165del,\N,\N,8/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503178,21:45944390:T>G,NM_144991.2:c.1336+1146A>C,\N,\N,8/11,Unknown significance,\N,intron_variant,0.093,0.001,1KG_EUR_AF,TSPEAR
503179,21:45944394:G>T,NM_144991.2:c.1336+1142C>A,\N,\N,8/11,Unknown significance,\N,intron_variant,0.516,0.001,1KG_EUR_AF,TSPEAR
503180,21:45944402:T>A,NM_144991.2:c.1336+1134A>T,\N,\N,8/11,Unknown significance,\N,intron_variant,4.647,0.001,1KG_EUR_AF,TSPEAR
503181,21:45944456:A>T,NM_144991.2:c.1336+1080T>A,\N,\N,8/11,Unknown significance,\N,intron_variant,1.869,0.0008,1KG_AFR_AF,TSPEAR
503182,21:45944457:G>A,NM_144991.2:c.1336+1079C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,2.539,0.001,1KG_EAS_AF,TSPEAR
503183,21:45944463:CAGTT>C,NM_144991.2:c.1336+1069_1336+1072del,\N,\N,8/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503184,21:45944471:C>G,NM_144991.2:c.1336+1065G>C,\N,\N,8/11,Benign,\N,intron_variant,1.078,0.1702,1KG_AFR_AF,TSPEAR
503185,21:45944524:G>C,NM_144991.2:c.1336+1012C>G,\N,\N,8/11,Unknown significance,\N,intron_variant,0.407,\N,\N,TSPEAR
503186,21:45944545:CAGTT>C,NM_144991.2:c.1336+987_1336+990del,\N,\N,8/11,Benign,\N,intron_variant,6.325,0.174,1KG_AFR_AF,TSPEAR
503187,21:45944553:CAGTT>C,NM_144991.2:c.1336+979_1336+982del,\N,\N,8/11,Unknown significance,\N,intron_variant,6.156,\N,\N,TSPEAR
503188,21:45944557:T>A,NM_144991.2:c.1336+979A>T,\N,\N,8/11,Unknown significance,\N,intron_variant,5.727,\N,\N,TSPEAR
503189,21:45944558:A>G,NM_144991.2:c.1336+978T>C,\N,\N,8/11,Unknown significance,\N,intron_variant,2.873,\N,\N,TSPEAR
503190,21:45944560:GTAAT>G,NM_144991.2:c.1336+972_1336+975del,\N,\N,8/11,Benign,\N,intron_variant,5.128,0.1641,1KG_AFR_AF,TSPEAR
503191,21:45944565:TAGTC>T,NM_144991.2:c.1336+967_1336+970del,\N,\N,8/11,Unknown significance,\N,intron_variant,4.848,\N,\N,TSPEAR
503192,21:45944588:T>C,NM_144991.2:c.1336+948A>G,\N,\N,8/11,Unknown significance,\N,intron_variant,1.829,0.001,1KG_EUR_AF,TSPEAR
503193,21:45944616:ACAGT>A,NM_144991.2:c.1336+916_1336+919del,\N,\N,8/11,Unknown significance,\N,intron_variant,13.27,0.0038,1KG_AFR_AF,TSPEAR
503194,21:45944623:GTCAA>G,NM_144991.2:c.1336+909_1336+912del,\N,\N,8/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503195,21:45944641:TAGTC>T,NM_144991.2:c.1336+891_1336+894del,\N,\N,8/11,Benign,\N,intron_variant,13.23,0.1641,1KG_AFR_AF,TSPEAR
503196,21:45944648:TCAGG>T,NM_144991.2:c.1336+884_1336+887del,\N,\N,8/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503197,21:45944656:TTAG>T,NM_144991.2:c.1336+877_1336+879del,\N,\N,8/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503198,21:45944660:TAGTC>T,NM_144991.2:c.1336+872_1336+875del,\N,\N,8/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503199,21:45944667:T>G,NM_144991.2:c.1336+869A>C,\N,\N,8/11,Unknown significance,\N,intron_variant,10.28,0.0043,1KG_AMR_AF,TSPEAR
503200,21:45944668:CAG>C,NM_144991.2:c.1336+866_1336+867del,\N,\N,8/11,Benign,\N,intron_variant,10.11,0.0204,1KG_AFR_AF,TSPEAR
503201,21:45944674:G>T,NM_144991.2:c.1336+862C>A,\N,\N,8/11,Unknown significance,\N,intron_variant,5.333,\N,\N,TSPEAR
503202,21:45944682:G>C,NM_144991.2:c.1336+854C>G,\N,\N,8/11,Unknown significance,\N,intron_variant,2.065,0.0031,1KG_SAS_AF,TSPEAR
503203,21:45944714:A>G,NM_144991.2:c.1336+822T>C,\N,\N,8/11,Unknown significance,\N,intron_variant,1.756,0.001,1KG_SAS_AF,TSPEAR
503204,21:45944727:GTAGTCAGTCAGCCAA>G,NM_144991.2:c.1336+794_1336+808del,\N,\N,8/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503205,21:45944743:TAGCCAGTC>T,NM_144991.2:c.1336+785_1336+792del,\N,\N,8/11,Unknown significance,\N,intron_variant,4.566,\N,\N,TSPEAR
503206,21:45944754:CCAGTCAGGTAGT>TAAGG,NM_144991.2:c.1336+770_1336+782delinsCCTTA,\N,\N,8/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503207,21:45944762:GTAGT>G,NM_144991.2:c.1336+770_1336+773del,\N,\N,8/11,Benign,\N,intron_variant,6.043,0.1649,1KG_AFR_AF,TSPEAR
503208,21:45944765:G>T,NM_144991.2:c.1336+771C>A,\N,\N,8/11,Unknown significance,\N,intron_variant,1.326,\N,\N,TSPEAR
503209,21:45944795:T>C,NM_144991.2:c.1336+741A>G,\N,\N,8/11,Benign,\N,intron_variant,1.516,0.0363,1KG_AFR_AF,TSPEAR
503210,21:45944795:TAGTC>T,NM_144991.2:c.1336+737_1336+740del,\N,\N,8/11,Unknown significance,\N,intron_variant,6.271,0.0038,1KG_AFR_AF,TSPEAR
503211,21:45944819:T>TAGTC,NM_144991.2:c.1336+713_1336+716dup,\N,\N,8/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503212,21:45944819:TAGTC>T,NM_144991.2:c.1336+713_1336+716del,\N,\N,8/11,Benign,\N,intron_variant,8.828,0.1649,1KG_AFR_AF,TSPEAR
503213,21:45944850:G>GCAGT,NM_144991.2:c.1336+682_1336+685dup,\N,\N,8/11,Unknown significance,\N,intron_variant,7.925,\N,\N,TSPEAR
503214,21:45944850:GCAGT>G,NM_144991.2:c.1336+682_1336+685del,\N,\N,8/11,Benign,\N,intron_variant,6.6,0.0288,1KG_EUR_AF,TSPEAR
503215,21:45944854:T>G,NM_144991.2:c.1336+682A>C,\N,\N,8/11,Unknown significance,\N,intron_variant,5.513,0.001,1KG_SAS_AF,TSPEAR
503216,21:45944874:T>G,NM_144991.2:c.1336+662A>C,\N,\N,8/11,Unknown significance,\N,intron_variant,2.579,\N,\N,TSPEAR
503217,21:45944875:G>C,NM_144991.2:c.1336+661C>G,\N,\N,8/11,Unknown significance,\N,intron_variant,0.021,\N,\N,TSPEAR
503218,21:45944897:G>C,NM_144991.2:c.1336+639C>G,\N,\N,8/11,Unknown significance,\N,intron_variant,0.342,\N,\N,TSPEAR
503219,21:45944902:ATAGT>A,NM_144991.2:c.1336+630_1336+633del,\N,\N,8/11,Unknown significance,\N,intron_variant,5.503,0.0029,1KG_AMR_AF,TSPEAR
503220,21:45944946:A>T,NM_144991.2:c.1336+590T>A,\N,\N,8/11,Unknown significance,\N,intron_variant,0.022,0.001,1KG_EAS_AF,TSPEAR
503221,21:45944947:TAGTC>T,NM_144991.2:c.1336+585_1336+588del,\N,\N,8/11,Unknown significance,\N,intron_variant,5.416,0.0045,1KG_AFR_AF,TSPEAR
503222,21:45944955:CAGTT>C,NM_144991.2:c.1336+577_1336+580del,\N,\N,8/11,Unknown significance,\N,intron_variant,3.847,\N,\N,TSPEAR
503223,21:45944958:T>C,NM_144991.2:c.1336+578A>G,\N,\N,8/11,Benign,\N,intron_variant,1.266,0.0749,1KG_AFR_AF,TSPEAR
503224,21:45944959:T>C,NM_144991.2:c.1336+577A>G,\N,\N,8/11,Benign,\N,intron_variant,0.08,0.0749,1KG_AFR_AF,TSPEAR
503225,21:45944987:C>T,NM_144991.2:c.1336+549G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,11.2,0.001,1KG_EAS_AF,TSPEAR
503226,21:45944997:A>G,NM_144991.2:c.1336+539T>C,\N,\N,8/11,Unknown significance,\N,intron_variant,11.9,0.0008,1KG_AFR_AF,TSPEAR
503227,21:45945014:TAGTC>T,NM_144991.2:c.1336+518_1336+521del,\N,\N,8/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503228,21:45945033:GTAGT>G,NM_144991.2:c.1336+499_1336+502del,\N,\N,8/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503229,21:45945037:T>CAGTC,NM_144991.2:c.1336+499delinsGACTG,\N,\N,8/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503230,21:45945038:T>TAGTC,NM_144991.2:c.1336+494_1336+497dup,\N,\N,8/11,Benign,\N,intron_variant,0.471,0.0537,1KG_AFR_AF,TSPEAR
503231,21:45945038:TAGTC>T,NM_144991.2:c.1336+494_1336+497del,\N,\N,8/11,Unknown significance,\N,intron_variant,4.507,\N,\N,TSPEAR
503232,21:45945038:TAGTCAGTC>T,NM_144991.2:c.1336+490_1336+497del,\N,\N,8/11,Unknown significance,\N,intron_variant,3.905,\N,\N,TSPEAR
503233,21:45945048:G>A,NM_144991.2:c.1336+488C>T,\N,\N,8/11,Benign,\N,intron_variant,0.123,0.1702,1KG_AFR_AF,TSPEAR
503234,21:45945061:G>A,NM_144991.2:c.1336+475C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,0.167,\N,\N,TSPEAR
503235,21:45945062:TAGTC>T,NM_144991.2:c.1336+470_1336+473del,\N,\N,8/11,Unknown significance,\N,intron_variant,4.526,\N,\N,TSPEAR
503236,21:45945066:C>T,NM_144991.2:c.1336+470G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,2.565,0.003,1KG_EAS_AF,TSPEAR
503237,21:45945070:C>T,NM_144991.2:c.1336+466G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,2.723,\N,\N,TSPEAR
503238,21:45945100:G>A,NM_144991.2:c.1336+436C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,1.202,0.001,1KG_EUR_AF,TSPEAR
503239,21:45945116:G>T,NM_144991.2:c.1336+420C>A,\N,\N,8/11,Unknown significance,\N,intron_variant,0.817,0.001,1KG_SAS_AF,TSPEAR
503240,21:45945119:A>G,NM_144991.2:c.1336+417T>C,\N,\N,8/11,Unknown significance,\N,intron_variant,2.019,0.0008,1KG_AFR_AF,TSPEAR
503241,21:45945141:GTAGT>G,NM_144991.2:c.1336+391_1336+394del,\N,\N,8/11,Unknown significance,\N,intron_variant,5.296,0.0045,1KG_AFR_AF,TSPEAR
503242,21:45945142:T>C,NM_144991.2:c.1336+394A>G,\N,\N,8/11,Benign,\N,intron_variant,2.434,0.1127,1KG_AFR_AF,TSPEAR
503243,21:45945146:TAGTCA>CG,NM_144991.2:c.1336+385_1336+390delinsCG,\N,\N,8/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503244,21:45945150:CAAG>C,NM_144991.2:c.1336+383_1336+385del,\N,\N,8/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503245,21:45945151:A>G,NM_144991.2:c.1336+385T>C,\N,\N,8/11,Benign,\N,intron_variant,2.373,0.1702,1KG_AFR_AF,TSPEAR
503246,21:45945153:G>C,NM_144991.2:c.1336+383C>G,\N,\N,8/11,Unknown significance,\N,intron_variant,0.441,\N,\N,TSPEAR
503247,21:45945169:G>A,NM_144991.2:c.1336+367C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,1.726,0.001,1KG_EAS_AF,TSPEAR
503248,21:45945175:C>A,NM_144991.2:c.1336+361G>T,\N,\N,8/11,Benign,\N,intron_variant,4.209,0.008,1KG_EUR_AF,TSPEAR
503249,21:45945185:GCAGT>G,NM_144991.2:c.1336+347_1336+350del,\N,\N,8/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503250,21:45945195:A>T,NM_144991.2:c.1336+341T>A,\N,\N,8/11,Unknown significance,\N,intron_variant,0.905,0.0014,1KG_AMR_AF,TSPEAR
503251,21:45945217:C>T,NM_144991.2:c.1336+319G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,0.275,0.0031,1KG_SAS_AF,TSPEAR
503252,21:45945218:G>A,NM_144991.2:c.1336+318C>T,\N,\N,8/11,Benign,\N,intron_variant,1.503,0.3033,1KG_AFR_AF,TSPEAR
503253,21:45945229:GAGTT>G,NM_144991.2:c.1336+303_1336+306del,\N,\N,8/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503254,21:45945245:C>T,NM_144991.2:c.1336+291G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,1.311,0.001,1KG_SAS_AF,TSPEAR
503255,21:45945249:TAGTC>T,NM_144991.2:c.1336+283_1336+286del,\N,\N,8/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503256,21:45945304:G>T,NM_144991.2:c.1336+232C>A,\N,\N,8/11,Unknown significance,\N,intron_variant,5.415,0.0008,1KG_AFR_AF,TSPEAR
503257,21:45945334:T>C,NM_144991.2:c.1336+202A>G,\N,\N,8/11,Unknown significance,\N,intron_variant,0.826,\N,\N,TSPEAR
503258,21:45945346:G>A,NM_144991.2:c.1336+190C>T,\N,\N,8/11,Benign,\N,intron_variant,1.634,0.0159,1KG_EUR_AF,TSPEAR
503259,21:45945385:CCAGA>C,NM_144991.2:c.1336+147_1336+150del,\N,\N,8/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503260,21:45945401:G>A,NM_144991.2:c.1336+135C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,0.277,0.0008,1KG_AFR_AF,TSPEAR
503261,21:45945411:G>A,NM_144991.2:c.1336+125C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,0.201,0.001,1KG_EAS_AF,TSPEAR
503262,21:45945412:C>T,NM_144991.2:c.1336+124G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,0.461,\N,\N,TSPEAR
503263,21:45945459:C>G,NM_144991.2:c.1336+77G>C,\N,\N,8/11,Benign,\N,intron_variant,1.246,0.0363,1KG_AFR_AF,TSPEAR
503264,21:45945465:C>T,NM_144991.2:c.1336+71G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,4.281,0.001,1KG_SAS_AF,TSPEAR
503265,21:45945484:G>A,NM_144991.2:c.1336+52C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,2.597,\N,\N,TSPEAR
503266,21:45945485:C>T,NM_144991.2:c.1336+51G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,4.778,0.0008,1KG_AFR_AF,TSPEAR
503267,21:45945487:C>T,NM_144991.2:c.1336+49G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,4.098,0.000115554,EXAC_EAS_AF,TSPEAR
503268,21:45945490:C>T,NM_144991.2:c.1336+46G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,3.271,0.0000150848,EXAC_NFE_AF,TSPEAR
503269,21:45945492:C>T,NM_144991.2:c.1336+44G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,6.892,0.000030145,EXAC_NFE_AF,TSPEAR
503270,21:45945496:G>A,NM_144991.2:c.1336+40C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,3.986,0.000231107,EXAC_EAS_AF,TSPEAR
503271,21:45945502:T>G,NM_144991.2:c.1336+34A>C,\N,\N,8/11,Unknown significance,\N,intron_variant,0.341,0.004,1KG_EUR_AF,TSPEAR
503272,21:45945507:T>C,NM_144991.2:c.1336+29A>G,\N,\N,8/11,Unknown significance,\N,intron_variant,3.119,0.000373692,EXAC_SAS_AF,TSPEAR
503273,21:45945508:C>G,NM_144991.2:c.1336+28G>C,\N,\N,8/11,Unknown significance,\N,intron_variant,0.863,0.0000150602,EXAC_NFE_AF,TSPEAR
503274,21:45945508:C>T,NM_144991.2:c.1336+28G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,1.909,0.0014,1KG_AMR_AF,TSPEAR
503275,21:45945510:C>T,NM_144991.2:c.1336+26G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,0.323,0.000346661,EXAC_EAS_AF,TSPEAR
503276,21:45945511:G>A,NM_144991.2:c.1336+25C>T,\N,\N,8/11,Benign,\N,intron_variant,4.415,0.1694,1KG_AFR_AF,TSPEAR
503277,21:45945511:G>C,NM_144991.2:c.1336+25C>G,\N,\N,8/11,Unknown significance,\N,intron_variant,1.461,\N,\N,TSPEAR
503278,21:45945513:T>G,NM_144991.2:c.1336+23A>C,\N,\N,8/11,Unknown significance,\N,intron_variant,3.62,0.000120446,EXAC_NFE_AF,TSPEAR
503279,21:45945514:G>A,NM_144991.2:c.1336+22C>T,\N,\N,8/11,Unknown significance,\N,intron_variant,0.813,0.0000618888,EXAC_SAS_AF,TSPEAR
503280,21:45945518:A>G,NM_144991.2:c.1336+18T>C,\N,\N,8/11,Unknown significance,\N,intron_variant,4.821,0.0000961354,EXAC_AFR_AF,TSPEAR
503281,21:45945524:C>T,NM_144991.2:c.1336+12G>A,\N,\N,8/11,Unknown significance,\N,intron_variant,4.854,0.000015034,EXAC_NFE_AF,TSPEAR
503282,21:45945534:A>T,NM_144991.2:c.1336+2T>A,\N,\N,8/11,Unknown significance,\N,splice_donor_variant,23.1,0.0000961354,EXAC_AFR_AF,TSPEAR
503283,21:45945537:T>C,NM_144991.2:c.1335A>G,NP_659428.2:p.Glu445=,8/12,\N,Unknown significance,\N,splice_region_variant&synonymous_variant,11.08,0.0043,1KG_AMR_AF,TSPEAR
503284,21:45945538:T>G,NM_144991.2:c.1334A>C,NP_659428.2:p.Glu445Ala,8/12,\N,Unknown significance,\N,missense_variant&splice_region_variant,20.6,0.0000607903,EXAC_SAS_AF,TSPEAR
503285,21:45945541:C>T,NM_144991.2:c.1331G>A,NP_659428.2:p.Arg444Gln,8/12,\N,Unknown significance,\N,missense_variant,34,0.001,1KG_EUR_AF,TSPEAR
503286,21:45945542:G>A,NM_144991.2:c.1330C>T,NP_659428.2:p.Arg444Trp,8/12,\N,Unknown significance,\N,missense_variant,25.4,0.0000150083,EXAC_NFE_AF,TSPEAR
503287,21:45945543:G>T,NM_144991.2:c.1329C>A,NP_659428.2:p.His443Gln,8/12,\N,Unknown significance,\N,missense_variant,26.5,0.0000600348,EXAC_NFE_AF,TSPEAR
503288,21:45945545:G>A,NM_144991.2:c.1327C>T,NP_659428.2:p.His443Tyr,8/12,\N,Unknown significance,\N,missense_variant,24.4,0.000116279,EVS_EA_AF,TSPEAR
503289,21:45945547:T>C,NM_144991.2:c.1325A>G,NP_659428.2:p.Asn442Ser,8/12,\N,Unknown significance,\N,missense_variant,25.4,0.001,1KG_EUR_AF,TSPEAR
503290,21:45945555:C>A,NM_144991.2:c.1317G>T,NP_659428.2:p.Ala439=,8/12,\N,Unknown significance,\N,synonymous_variant,22,0.000115554,EXAC_EAS_AF,TSPEAR
503291,21:45945555:C>T,NM_144991.2:c.1317G>A,NP_659428.2:p.Ala439=,8/12,\N,Unknown significance,\N,synonymous_variant,17.77,0.000115554,EXAC_EAS_AF,TSPEAR
503292,21:45945556:G>A,NM_144991.2:c.1316C>T,NP_659428.2:p.Ala439Val,8/12,\N,Likely benign,\N,missense_variant,19.12,0.000015002,EXAC_NFE_AF,TSPEAR
503293,21:45945556:G>T,NM_144991.2:c.1316C>A,NP_659428.2:p.Ala439Glu,8/12,\N,Unknown significance,\N,missense_variant,28.5,0.000259157,EXAC_AMR_AF,TSPEAR
503294,21:45945567:C>A,NM_144991.2:c.1305G>T,NP_659428.2:p.Glu435Asp,8/12,\N,Unknown significance,\N,missense_variant,24.2,0.001,1KG_EAS_AF,TSPEAR
503295,21:45945572:C>T,NM_144991.2:c.1300G>A,NP_659428.2:p.Gly434Arg,8/12,\N,Unknown significance,\N,missense_variant,25.4,0.0000149939,EXAC_NFE_AF,TSPEAR
503296,21:45945582:G>A,NM_144991.2:c.1290C>T,NP_659428.2:p.Phe430=,8/12,\N,Unknown significance,\N,synonymous_variant,14.43,0.000060562,EXAC_SAS_AF,TSPEAR
503297,21:45945591:C>T,NM_144991.2:c.1281G>A,NP_659428.2:p.Trp427Ter,8/12,\N,Unknown significance,\N,stop_gained,41,0.000060562,EXAC_SAS_AF,TSPEAR
503298,21:45945598:C>T,NM_144991.2:c.1274G>A,NP_659428.2:p.Arg425Gln,8/12,\N,Unknown significance,\N,missense_variant,27.3,0.001,1KG_EAS_AF,TSPEAR
503299,21:45945599:G>A,NM_144991.2:c.1273C>T,NP_659428.2:p.Arg425Ter,8/12,\N,Unknown significance,\N,stop_gained,39,0.000116279,EVS_EA_AF,TSPEAR
503300,21:45945602:C>T,NM_144991.2:c.1270G>A,NP_659428.2:p.Ala424Thr,8/12,\N,Unknown significance,\N,missense_variant,33,0.000115554,EXAC_EAS_AF,TSPEAR
503301,21:45945603:G>A,NM_144991.2:c.1269C>T,NP_659428.2:p.Ser423=,8/12,\N,Unknown significance,\N,synonymous_variant,10.99,0.0000149844,EXAC_NFE_AF,TSPEAR
503302,21:45945604:C>CTG,NM_144991.2:c.1266_1267dup,NP_659428.2:p.Ser423ThrfsTer147,8/12,\N,Unknown significance,\N,frameshift_variant,33,0.0000149844,EXAC_NFE_AF,TSPEAR
503303,21:45945604:C>T,NM_144991.2:c.1268G>A,NP_659428.2:p.Ser423Asn,8/12,\N,Unknown significance,\N,missense_variant,16.96,0.000060562,EXAC_SAS_AF,TSPEAR
503304,21:45945604:CTG>C,NM_144991.2:c.1266_1267del,NP_659428.2:p.His422GlnfsTer135,8/12,\N,Unknown significance,\N,frameshift_variant,34,0.000060562,EXAC_SAS_AF,TSPEAR
503305,21:45945605:T>A,NM_144991.2:c.1267A>T,NP_659428.2:p.Ser423Cys,8/12,\N,Unknown significance,\N,missense_variant,22.8,0.0000149849,EXAC_NFE_AF,TSPEAR
503306,21:45945608:G>A,NM_144991.2:c.1264C>T,NP_659428.2:p.His422Tyr,8/12,\N,Unknown significance,\N,missense_variant,12.98,0.000060562,EXAC_SAS_AF,TSPEAR
503307,21:45945612:G>A,NM_144991.2:c.1260C>T,NP_659428.2:p.Ala420=,8/12,\N,Unknown significance,\N,synonymous_variant,5.497,\N,\N,TSPEAR
503308,21:45945613:G>A,NM_144991.2:c.1259C>T,NP_659428.2:p.Ala420Val,8/12,\N,Likely benign,\N,missense_variant,12.35,\N,\N,TSPEAR
503309,21:45945616:AT>A,NM_144991.2:c.1255del,NP_659428.2:p.Ile419LeufsTer150,8/12,\N,Unknown significance,\N,frameshift_variant,27.1,0.00030281,EXAC_SAS_AF,TSPEAR
503310,21:45945625:T>G,NM_144991.2:c.1247A>C,NP_659428.2:p.Tyr416Ser,8/12,\N,Unknown significance,\N,missense_variant,25.5,0.0000960984,EXAC_AFR_AF,TSPEAR
503311,21:45945626:A>G,NM_144991.2:c.1246T>C,NP_659428.2:p.Tyr416His,8/12,\N,Unknown significance,\N,missense_variant,10.11,0.001,1KG_SAS_AF,TSPEAR
503312,21:45945631:G>A,NM_144991.2:c.1241C>T,NP_659428.2:p.Thr414Ile,8/12,\N,Likely benign,\N,missense_variant,15.85,0.0000960984,EXAC_AFR_AF,TSPEAR
503313,21:45945632:T>C,NM_144991.2:c.1240A>G,NP_659428.2:p.Thr414Ala,8/12,\N,Likely benign,\N,missense_variant,7.014,0.000666182,EXAC_SAS_AF,TSPEAR
503314,21:45945633:A>G,NM_144991.2:c.1239T>C,NP_659428.2:p.Phe413=,8/12,\N,Unknown significance,\N,synonymous_variant,3.506,0.0000149835,EXAC_NFE_AF,TSPEAR
503315,21:45945637:T>G,NM_144991.2:c.1235A>C,NP_659428.2:p.Lys412Thr,8/12,\N,Unknown significance,\N,missense_variant,23,0.0000960984,EXAC_AFR_AF,TSPEAR
503316,21:45945648:G>C,NM_144991.2:c.1224C>G,NP_659428.2:p.His408Gln,8/12,\N,Benign,\N,missense_variant,2.214,0.0981252,EXAC_FIN_AF,TSPEAR
503317,21:45945664:A>G,NM_144991.2:c.1208T>C,NP_659428.2:p.Ile403Thr,8/12,\N,Unknown significance,\N,missense_variant,26.5,0.000060562,EXAC_SAS_AF,TSPEAR
503318,21:45945669:A>G,NM_144991.2:c.1203T>C,NP_659428.2:p.Ser401=,8/12,\N,Unknown significance,\N,synonymous_variant,0.352,0.0000149853,EXAC_NFE_AF,TSPEAR
503319,21:45945684:C>T,NM_144991.2:c.1188G>A,NP_659428.2:p.Lys396=,8/12,\N,Unknown significance,\N,synonymous_variant,12.65,0.000060562,EXAC_SAS_AF,TSPEAR
503320,21:45945687:C>A,NM_144991.2:c.1185G>T,NP_659428.2:p.Glu395Asp,8/12,\N,Likely benign,\N,missense_variant,0.405,0.0008,1KG_AFR_AF,TSPEAR
503321,21:45945693:TG>T,NM_144991.2:c.1178del,NP_659428.2:p.Pro393GlnfsTer19,8/12,\N,Unknown significance,\N,frameshift_variant,25.8,0.000172741,EXAC_AMR_AF,TSPEAR
503322,21:45945694:G>C,NM_144991.2:c.1178C>G,NP_659428.2:p.Pro393Arg,8/12,\N,Likely benign,\N,missense_variant,1.796,0.000116279,EVS_EA_AF,TSPEAR
503323,21:45945698:C>G,NM_144991.2:c.1174G>C,NP_659428.2:p.Glu392Gln,8/12,\N,Likely benign,\N,missense_variant,22.7,0.000116279,EVS_EA_AF,TSPEAR
503324,21:45945704:T>C,NM_144991.2:c.1168A>G,NP_659428.2:p.Asn390Asp,8/12,\N,Unknown significance,\N,missense_variant,26.3,0.0008,1KG_AFR_AF,TSPEAR
503325,21:45945708:C>T,NM_144991.2:c.1164G>A,NP_659428.2:p.Val388=,8/12,\N,Unknown significance,\N,synonymous_variant,11.99,\N,\N,TSPEAR
503326,21:45945711:T>G,NM_144991.2:c.1161A>C,NP_659428.2:p.Ala387=,8/12,\N,Unknown significance,\N,synonymous_variant,5.507,0.0000149952,EXAC_NFE_AF,TSPEAR
503327,21:45945712:G>T,NM_144991.2:c.1160C>A,NP_659428.2:p.Ala387Glu,8/12,\N,Unknown significance,\N,missense_variant,25.3,0.0000299922,EXAC_NFE_AF,TSPEAR
503328,21:45945715:AGGAAGAT>A,NM_144991.2:c.1150_1156del,NP_659428.2:p.Ile384TrpfsTer26,8/12,\N,Unknown significance,\N,frameshift_variant&splice_region_variant,33,0.000121286,EXAC_SAS_AF,TSPEAR
503329,21:45945721:A>G,NM_144991.2:c.1151T>C,NP_659428.2:p.Ile384Thr,8/12,\N,Unknown significance,\N,missense_variant&splice_region_variant,12.83,0.000346741,EXAC_EAS_AF,TSPEAR
503330,21:45945723:C>G,NM_144991.2:c.1150-1G>C,\N,\N,7/11,Unknown significance,\N,splice_acceptor_variant,24.5,0.0000150087,EXAC_NFE_AF,TSPEAR
503331,21:45945724:TGAAA>T,NM_144991.2:c.1150-6_1150-3del,\N,\N,7/11,Unknown significance,\N,splice_region_variant&intron_variant,14.09,\N,\N,TSPEAR
503332,21:45945731:G>C,NM_144991.2:c.1150-9C>G,\N,\N,7/11,Unknown significance,\N,intron_variant,5.438,0.0000150204,EXAC_NFE_AF,TSPEAR
503333,21:45945732:A>C,NM_144991.2:c.1150-10T>G,\N,\N,7/11,Unknown significance,\N,intron_variant,5.054,0.00023116,EXAC_EAS_AF,TSPEAR
503334,21:45945734:T>G,NM_144991.2:c.1150-12A>C,\N,\N,7/11,Unknown significance,\N,intron_variant,1.786,0.0000150249,EXAC_NFE_AF,TSPEAR
503335,21:45945739:C>T,NM_144991.2:c.1150-17G>A,\N,\N,7/11,Unknown significance,\N,intron_variant,6.097,0.00011558,EXAC_EAS_AF,TSPEAR
503336,21:45945740:G>A,NM_144991.2:c.1150-18C>T,\N,\N,7/11,Unknown significance,\N,intron_variant,3.912,0.00011558,EXAC_EAS_AF,TSPEAR
503337,21:45945741:G>A,NM_144991.2:c.1150-19C>T,\N,\N,7/11,Unknown significance,\N,intron_variant,2.566,0.000232558,EVS_EA_AF,TSPEAR
503338,21:45945742:G>A,NM_144991.2:c.1150-20C>T,\N,\N,7/11,Benign,\N,intron_variant,4.428,0.00522015,EVS_AA_AF,TSPEAR
503339,21:45945747:C>T,NM_144991.2:c.1150-25G>A,\N,\N,7/11,Unknown significance,\N,intron_variant,5.596,0.00007524,EXAC_NFE_AF,TSPEAR
503340,21:45945748:G>A,NM_144991.2:c.1150-26C>T,\N,\N,7/11,Unknown significance,\N,intron_variant,2.298,0.000030096,EXAC_NFE_AF,TSPEAR
503341,21:45945748:G>C,NM_144991.2:c.1150-26C>G,\N,\N,7/11,Benign,\N,intron_variant,0.608,0.0133091,EXAC_FIN_AF,TSPEAR
503342,21:45945751:G>T,NM_144991.2:c.1150-29C>A,\N,\N,7/11,Unknown significance,\N,intron_variant,0.422,0.0000864304,EXAC_AMR_AF,TSPEAR
503343,21:45945754:C>T,NM_144991.2:c.1150-32G>A,\N,\N,7/11,Unknown significance,\N,intron_variant,6.047,0.000194137,EXAC_AFR_AF,TSPEAR
503344,21:45945757:C>T,NM_144991.2:c.1150-35G>A,\N,\N,7/11,Unknown significance,\N,intron_variant,5.419,0.0000622355,EXAC_SAS_AF,TSPEAR
503345,21:45945762:G>A,NM_144991.2:c.1150-40C>T,\N,\N,7/11,Unknown significance,\N,intron_variant,3.713,0.0000150698,EXAC_NFE_AF,TSPEAR
503346,21:45945763:T>C,NM_144991.2:c.1150-41A>G,\N,\N,7/11,Unknown significance,\N,intron_variant,0.498,0.0000150657,EXAC_NFE_AF,TSPEAR
503347,21:45945764:C>T,NM_144991.2:c.1150-42G>A,\N,\N,7/11,Unknown significance,\N,intron_variant,8.377,0.0000452735,EXAC_NFE_AF,TSPEAR
503348,21:45945765:G>A,NM_144991.2:c.1150-43C>T,\N,\N,7/11,Unknown significance,\N,intron_variant,1.437,0.0000301832,EXAC_NFE_AF,TSPEAR
503349,21:45945773:C>T,NM_144991.2:c.1150-51G>A,\N,\N,7/11,Unknown significance,\N,intron_variant,5.516,0.00001514,EXAC_NFE_AF,TSPEAR
503350,21:45945774:G>A,NM_144991.2:c.1150-52C>T,\N,\N,7/11,Unknown significance,\N,intron_variant,5.725,0.000886001,EXAC_AFR_AF,TSPEAR
503351,21:45945774:G>T,NM_144991.2:c.1150-52C>A,\N,\N,7/11,Unknown significance,\N,intron_variant,4.831,0.00150716,EVS_AA_AF,TSPEAR
503352,21:45945805:C>T,NM_144991.2:c.1150-83G>A,\N,\N,7/11,Unknown significance,\N,intron_variant,5.766,0.002,1KG_EUR_AF,TSPEAR
503353,21:45945835:G>A,NM_144991.2:c.1150-113C>T,\N,\N,7/11,Unknown significance,\N,intron_variant,1.263,\N,\N,TSPEAR
503354,21:45945841:G>C,NM_144991.2:c.1150-119C>G,\N,\N,7/11,Unknown significance,\N,intron_variant,7.076,\N,\N,TSPEAR
503355,21:45945862:C>T,NM_144991.2:c.1150-140G>A,\N,\N,7/11,Benign,\N,intron_variant,0.088,0.0234,1KG_AFR_AF,TSPEAR
503356,21:45945869:C>T,NM_144991.2:c.1150-147G>A,\N,\N,7/11,Unknown significance,\N,intron_variant,1.787,0.001,1KG_SAS_AF,TSPEAR
503357,21:45945878:ATGG>A,NM_144991.2:c.1150-159_1150-157del,\N,\N,7/11,Benign,\N,intron_variant,4.684,0.005,1KG_EUR_AF,TSPEAR
503358,21:45945884:G>A,NM_144991.2:c.1150-162C>T,\N,\N,7/11,Unknown significance,\N,intron_variant,3.732,\N,\N,TSPEAR
503359,21:45945891:C>T,NM_144991.2:c.1150-169G>A,\N,\N,7/11,Unknown significance,\N,intron_variant,0.031,0.002,1KG_EAS_AF,TSPEAR
503360,21:45945899:C>T,NM_144991.2:c.1150-177G>A,\N,\N,7/11,Benign,\N,intron_variant,0.486,0.0144,1KG_AFR_AF,TSPEAR
503361,21:45945940:C>A,NM_144991.2:c.1150-218G>T,\N,\N,7/11,Unknown significance,\N,intron_variant,4.355,\N,\N,TSPEAR
503362,21:45946048:G>A,NM_144991.2:c.1150-326C>T,\N,\N,7/11,Unknown significance,\N,intron_variant,2.845,0.001,1KG_SAS_AF,TSPEAR
503363,21:45946062:C>T,NM_144991.2:c.1150-340G>A,\N,\N,7/11,Unknown significance,\N,intron_variant,0.48,0.001,1KG_SAS_AF,TSPEAR
503364,21:45946063:G>A,NM_144991.2:c.1150-341C>T,\N,\N,7/11,Unknown significance,\N,intron_variant,0.235,\N,\N,TSPEAR
503365,21:45946069:C>T,NM_144991.2:c.1150-347G>A,\N,\N,7/11,Benign,\N,intron_variant,0.224,0.0106,1KG_AFR_AF,TSPEAR
503366,21:45946104:C>T,NM_144991.2:c.1150-382G>A,\N,\N,7/11,Unknown significance,\N,intron_variant,4.313,\N,\N,TSPEAR
503367,21:45946110:G>A,NM_144991.2:c.1150-388C>T,\N,\N,7/11,Unknown significance,\N,intron_variant,4.689,0.001,1KG_EAS_AF,TSPEAR
503368,21:45946130:G>A,NM_144991.2:c.1150-408C>T,\N,\N,7/11,Unknown significance,\N,intron_variant,3.557,\N,\N,TSPEAR
503369,21:45946147:C>T,NM_144991.2:c.1150-425G>A,\N,\N,7/11,Unknown significance,\N,intron_variant,0.653,\N,\N,TSPEAR
503370,21:45946151:A>G,NM_144991.2:c.1150-429T>C,\N,\N,7/11,Unknown significance,\N,intron_variant,1.152,0.002,1KG_SAS_AF,TSPEAR
503371,21:45946157:C>A,NM_144991.2:c.1150-435G>T,\N,\N,7/11,Unknown significance,\N,intron_variant,7.378,\N,\N,TSPEAR
503372,21:45946199:G>A,NM_144991.2:c.1150-477C>T,\N,\N,7/11,Unknown significance,\N,intron_variant,1.402,\N,\N,TSPEAR
503373,21:45946221:G>A,NM_144991.2:c.1150-499C>T,\N,\N,7/11,Unknown significance,\N,intron_variant,0.421,\N,\N,TSPEAR
503374,21:45946229:T>TGGAG,NM_144991.2:c.1150-511_1150-508dup,\N,\N,7/11,Unknown significance,\N,intron_variant,0.379,\N,\N,TSPEAR
503375,21:45946232:A>C,NM_144991.2:c.1150-510T>G,\N,\N,7/11,Unknown significance,\N,intron_variant,0.042,0.0008,1KG_AFR_AF,TSPEAR
503376,21:45946241:C>T,NM_144991.2:c.1150-519G>A,\N,\N,7/11,Unknown significance,\N,intron_variant,1.19,\N,\N,TSPEAR
503377,21:45946242:G>A,NM_144991.2:c.1150-520C>T,\N,\N,7/11,Benign,\N,intron_variant,0.423,0.0151,1KG_AFR_AF,TSPEAR
503378,21:45946314:A>G,NM_144991.2:c.1150-592T>C,\N,\N,7/11,Unknown significance,\N,intron_variant,2.553,0.0008,1KG_AFR_AF,TSPEAR
503379,21:45946327:G>A,NM_144991.2:c.1150-605C>T,\N,\N,7/11,Unknown significance,\N,intron_variant,1.497,\N,\N,TSPEAR
503380,21:45946330:A>C,NM_144991.2:c.1150-608T>G,\N,\N,7/11,Unknown significance,\N,intron_variant,1.34,0.0008,1KG_AFR_AF,TSPEAR
503381,21:45946331:AG>A,NM_144991.2:c.1150-610del,\N,\N,7/11,Benign,\N,intron_variant,0.24,0.1324,1KG_AFR_AF,TSPEAR
503382,21:45946332:G>T,NM_144991.2:c.1150-610C>A,\N,\N,7/11,Unknown significance,\N,intron_variant,0.364,\N,\N,TSPEAR
503383,21:45946376:C>CA,NM_144991.2:c.1150-655dup,\N,\N,7/11,Unknown significance,\N,intron_variant,6.211,\N,\N,TSPEAR
503384,21:45946376:C>CAAAA,NM_144991.2:c.1150-658_1150-655dup,\N,\N,7/11,Unknown significance,\N,intron_variant,5.758,\N,\N,TSPEAR
503385,21:45946376:CAA>C,NM_144991.2:c.1150-656_1150-655del,\N,\N,7/11,Unknown significance,\N,intron_variant,7.141,\N,\N,TSPEAR
503386,21:45946382:A>G,NM_144991.2:c.1150-660T>C,\N,\N,7/11,Unknown significance,\N,intron_variant,1.419,\N,\N,TSPEAR
503387,21:45946407:C>T,NM_144991.2:c.1150-685G>A,\N,\N,7/11,Unknown significance,\N,intron_variant,1.23,0.0014,1KG_AMR_AF,TSPEAR
503388,21:45946408:G>A,NM_144991.2:c.1150-686C>T,\N,\N,7/11,Unknown significance,\N,intron_variant,0.456,\N,\N,TSPEAR
503389,21:45946434:C>T,NM_144991.2:c.1150-712G>A,\N,\N,7/11,Unknown significance,\N,intron_variant,0.841,\N,\N,TSPEAR
503390,21:45946456:A>C,NM_144991.2:c.1149+719T>G,\N,\N,7/11,Unknown significance,\N,intron_variant,0.06,\N,\N,TSPEAR
503391,21:45946496:C>T,NM_144991.2:c.1149+679G>A,\N,\N,7/11,Unknown significance,\N,intron_variant,2.048,\N,\N,TSPEAR
503392,21:45946497:T>A,NM_144991.2:c.1149+678A>T,\N,\N,7/11,Unknown significance,\N,intron_variant,3.471,\N,\N,TSPEAR
503393,21:45946516:G>A,NM_144991.2:c.1149+659C>T,\N,\N,7/11,Unknown significance,\N,intron_variant,1.416,0.001,1KG_EAS_AF,TSPEAR
503394,21:45946520:G>A,NM_144991.2:c.1149+655C>T,\N,\N,7/11,Benign,\N,intron_variant,0.24,0.0696,1KG_AFR_AF,TSPEAR
503395,21:45946576:C>G,NM_144991.2:c.1149+599G>C,\N,\N,7/11,Unknown significance,\N,intron_variant,7.338,0.0008,1KG_AFR_AF,TSPEAR
503396,21:45946643:T>C,NM_144991.2:c.1149+532A>G,\N,\N,7/11,Benign,\N,intron_variant,2.303,0.0149,1KG_EAS_AF,TSPEAR
503397,21:45946683:C>T,NM_144991.2:c.1149+492G>A,\N,\N,7/11,Unknown significance,\N,intron_variant,1.874,\N,\N,TSPEAR
503398,21:45946703:C>T,NM_144991.2:c.1149+472G>A,\N,\N,7/11,Unknown significance,\N,intron_variant,4.641,0.0008,1KG_AFR_AF,TSPEAR
503399,21:45946725:A>G,NM_144991.2:c.1149+450T>C,\N,\N,7/11,Unknown significance,\N,intron_variant,1.284,\N,\N,TSPEAR
503400,21:45946731:C>T,NM_144991.2:c.1149+444G>A,\N,\N,7/11,Unknown significance,\N,intron_variant,4.632,\N,\N,TSPEAR
503401,21:45946732:G>A,NM_144991.2:c.1149+443C>T,\N,\N,7/11,Unknown significance,\N,intron_variant,0.487,\N,\N,TSPEAR
503402,21:45946737:C>T,NM_144991.2:c.1149+438G>A,\N,\N,7/11,Unknown significance,\N,intron_variant,5.749,\N,\N,TSPEAR
503403,21:45946755:G>T,NM_144991.2:c.1149+420C>A,\N,\N,7/11,Unknown significance,\N,intron_variant,0.473,\N,\N,TSPEAR
503404,21:45946787:C>T,NM_144991.2:c.1149+388G>A,\N,\N,7/11,Unknown significance,\N,intron_variant,0.06,\N,\N,TSPEAR
503405,21:45946814:G>T,NM_144991.2:c.1149+361C>A,\N,\N,7/11,Unknown significance,\N,intron_variant,0.59,0.001,1KG_EUR_AF,TSPEAR
503406,21:45946815:G>A,NM_144991.2:c.1149+360C>T,\N,\N,7/11,Unknown significance,\N,intron_variant,4.085,\N,\N,TSPEAR
503407,21:45946819:A>AG,NM_144991.2:c.1149+355dup,\N,\N,7/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503408,21:45946825:G>A,NM_144991.2:c.1149+350C>T,\N,\N,7/11,Unknown significance,\N,intron_variant,1.338,0.001,1KG_EUR_AF,TSPEAR
503409,21:45946847:G>A,NM_144991.2:c.1149+328C>T,\N,\N,7/11,Unknown significance,\N,intron_variant,2.592,0.002,1KG_EUR_AF,TSPEAR
503410,21:45946851:C>T,NM_144991.2:c.1149+324G>A,\N,\N,7/11,Unknown significance,\N,intron_variant,0.573,0.0008,1KG_AFR_AF,TSPEAR
503411,21:45946865:T>C,NM_144991.2:c.1149+310A>G,\N,\N,7/11,Unknown significance,\N,intron_variant,1.294,\N,\N,TSPEAR
503412,21:45946869:C>T,NM_144991.2:c.1149+306G>A,\N,\N,7/11,Unknown significance,\N,intron_variant,2.241,0.004,1KG_EAS_AF,TSPEAR
503413,21:45946911:C>T,NM_144991.2:c.1149+264G>A,\N,\N,7/11,Benign,\N,intron_variant,0.02,0.0106,1KG_AFR_AF,TSPEAR
503414,21:45946912:G>A,NM_144991.2:c.1149+263C>T,\N,\N,7/11,Unknown significance,\N,intron_variant,0.057,0.0008,1KG_AFR_AF,TSPEAR
503415,21:45946916:G>C,NM_144991.2:c.1149+259C>G,\N,\N,7/11,Unknown significance,\N,intron_variant,3.036,\N,\N,TSPEAR
503416,21:45946929:C>T,NM_144991.2:c.1149+246G>A,\N,\N,7/11,Unknown significance,\N,intron_variant,2.287,0.0015,1KG_AFR_AF,TSPEAR
503417,21:45946957:C>T,NM_144991.2:c.1149+218G>A,\N,\N,7/11,Benign,\N,intron_variant,7.073,0.1702,1KG_AFR_AF,TSPEAR
503418,21:45946958:G>A,NM_144991.2:c.1149+217C>T,\N,\N,7/11,Benign,\N,intron_variant,2.097,0.025,1KG_AFR_AF,TSPEAR
503419,21:45946961:C>T,NM_144991.2:c.1149+214G>A,\N,\N,7/11,Unknown significance,\N,intron_variant,2.207,\N,\N,TSPEAR
503420,21:45946962:G>A,NM_144991.2:c.1149+213C>T,\N,\N,7/11,Unknown significance,\N,intron_variant,0.03,0.0014,1KG_AMR_AF,TSPEAR
503421,21:45946969:G>A,NM_144991.2:c.1149+206C>T,\N,\N,7/11,Unknown significance,\N,intron_variant,5.306,0.0008,1KG_AFR_AF,TSPEAR
503422,21:45947029:G>T,NM_144991.2:c.1149+146C>A,\N,\N,7/11,Benign,\N,intron_variant,0.625,0.0106,1KG_AFR_AF,TSPEAR
503423,21:45947034:T>C,NM_144991.2:c.1149+141A>G,\N,\N,7/11,Benign,\N,intron_variant,2.08,0.18,1KG_AFR_AF,TSPEAR
503424,21:45947051:G>T,NM_144991.2:c.1149+124C>A,\N,\N,7/11,Benign,\N,intron_variant,0.724,0.007,1KG_EUR_AF,TSPEAR
503425,21:45947058:C>T,NM_144991.2:c.1149+117G>A,\N,\N,7/11,Unknown significance,\N,intron_variant,1.111,\N,\N,TSPEAR
503426,21:45947059:G>A,NM_144991.2:c.1149+116C>T,\N,\N,7/11,Unknown significance,\N,intron_variant,1.323,0.001,1KG_EAS_AF|1KG_EUR_AF,TSPEAR
503427,21:45947069:C>T,NM_144991.2:c.1149+106G>A,\N,\N,7/11,Unknown significance,\N,intron_variant,5.058,\N,\N,TSPEAR
503428,21:45947079:T>A,NM_144991.2:c.1149+96A>T,\N,\N,7/11,Unknown significance,\N,intron_variant,4.74,0.0014,1KG_AMR_AF,TSPEAR
503429,21:45947096:C>A,NM_144991.2:c.1149+79G>T,\N,\N,7/11,Benign,\N,intron_variant,5.661,0.0083,1KG_AFR_AF,TSPEAR
503430,21:45947099:T>C,NM_144991.2:c.1149+76A>G,\N,\N,7/11,Unknown significance,\N,intron_variant,1.044,0.0031,1KG_SAS_AF,TSPEAR
503431,21:45947108:C>T,NM_144991.2:c.1149+67G>A,\N,\N,7/11,Unknown significance,\N,intron_variant,5.466,0.001,1KG_SAS_AF,TSPEAR
503432,21:45947111:C>T,NM_144991.2:c.1149+64G>A,\N,\N,7/11,Benign,\N,intron_variant,3.14,0.0681,1KG_AFR_AF,TSPEAR
503433,21:45947122:T>C,NM_144991.2:c.1149+53A>G,\N,\N,7/11,Unknown significance,\N,intron_variant,4.202,0.001,1KG_SAS_AF,TSPEAR
503434,21:45947124:G>A,NM_144991.2:c.1149+51C>T,\N,\N,7/11,Unknown significance,\N,intron_variant,0.693,0.0014,1KG_AMR_AF,TSPEAR
503435,21:45947124:G>C,NM_144991.2:c.1149+51C>G,\N,\N,7/11,Unknown significance,\N,intron_variant,0.109,0.000117592,EXAC_EAS_AF,TSPEAR
503436,21:45947130:T>C,NM_144991.2:c.1149+45A>G,\N,\N,7/11,Unknown significance,\N,intron_variant,1.858,0.0000302133,EXAC_NFE_AF,TSPEAR
503437,21:45947132:C>G,NM_144991.2:c.1149+43G>C,\N,\N,7/11,Unknown significance,\N,intron_variant,4.604,0.000116279,EVS_EA_AF,TSPEAR
503438,21:45947142:G>A,NM_144991.2:c.1149+33C>T,\N,\N,7/11,Unknown significance,\N,intron_variant,4.051,0.0000965437,EXAC_AFR_AF,TSPEAR
503439,21:45947147:T>C,NM_144991.2:c.1149+28A>G,\N,\N,7/11,Unknown significance,\N,intron_variant,2.193,0.0000150435,EXAC_NFE_AF,TSPEAR
503440,21:45947151:G>A,NM_144991.2:c.1149+24C>T,\N,\N,7/11,Unknown significance,\N,intron_variant,6.343,0.000116063,EXAC_EAS_AF,TSPEAR
503441,21:45947151:GAA>G,NM_144991.2:c.1149+22_1149+23del,\N,\N,7/11,Unknown significance,\N,intron_variant,0.064,0.00111111,EXAC_OTH_AF,TSPEAR
503442,21:45947160:C>T,NM_144991.2:c.1149+15G>A,\N,\N,7/11,Unknown significance,\N,intron_variant,1.046,0.000115607,EXAC_EAS_AF,TSPEAR
503443,21:45947161:G>A,NM_144991.2:c.1149+14C>T,\N,\N,7/11,Unknown significance,\N,intron_variant,2.505,0.001,1KG_SAS_AF,TSPEAR
503444,21:45947169:A>G,NM_144991.2:c.1149+6T>C,\N,\N,7/11,Unknown significance,\N,splice_region_variant&intron_variant,3.246,0.0000961723,EXAC_AFR_AF,TSPEAR
503445,21:45947170:C>T,NM_144991.2:c.1149+5G>A,\N,\N,7/11,Unknown significance,\N,splice_region_variant&intron_variant,9.99,0.000116279,EVS_EA_AF,TSPEAR
503446,21:45947180:T>C,NM_144991.2:c.1144A>G,NP_659428.2:p.Lys382Glu,7/12,\N,Likely benign,\N,missense_variant,7.586,0.000115554,EXAC_EAS_AF,TSPEAR
503447,21:45947183:C>T,NM_144991.2:c.1141G>A,NP_659428.2:p.Gly381Arg,7/12,\N,Unknown significance,\N,missense_variant,28.7,0.00158874,EVS_AA_AF,TSPEAR
503448,21:45947184:G>A,NM_144991.2:c.1140C>T,NP_659428.2:p.Ile380=,7/12,\N,Unknown significance,\N,synonymous_variant,7.777,0.0000864155,EXAC_AMR_AF,TSPEAR
503449,21:45947185:A>T,NM_144991.2:c.1139T>A,NP_659428.2:p.Ile380Asn,7/12,\N,Unknown significance,\N,missense_variant,26.5,0.0000149898,EXAC_NFE_AF,TSPEAR
503450,21:45947186:T>C,NM_144991.2:c.1138A>G,NP_659428.2:p.Ile380Val,7/12,\N,Unknown significance,\N,missense_variant,12.32,0.000121124,EXAC_SAS_AF,TSPEAR
503451,21:45947206:T>C,NM_144991.2:c.1118A>G,NP_659428.2:p.Gln373Arg,7/12,\N,Unknown significance,\N,missense_variant,6.01,0.000060562,EXAC_SAS_AF,TSPEAR
503452,21:45947207:G>A,NM_144991.2:c.1117C>T,NP_659428.2:p.Gln373Ter,7/12,\N,Unknown significance,\N,stop_gained,37,0.000115554,EXAC_EAS_AF,TSPEAR
503453,21:45947214:G>T,NM_144991.2:c.1110C>A,NP_659428.2:p.His370Gln,7/12,\N,Likely benign,\N,missense_variant,11.24,0.001,1KG_SAS_AF,TSPEAR
503454,21:45947217:C>A,NM_144991.2:c.1107G>T,NP_659428.2:p.Thr369=,7/12,\N,Unknown significance,\N,synonymous_variant,15.24,0.000029976,EXAC_NFE_AF,TSPEAR
503455,21:45947217:C>T,NM_144991.2:c.1107G>A,NP_659428.2:p.Thr369=,7/12,\N,Unknown significance,\N,synonymous_variant,13.29,0.000813953,EVS_EA_AF,TSPEAR
503456,21:45947218:G>A,NM_144991.2:c.1106C>T,NP_659428.2:p.Thr369Met,7/12,\N,Unknown significance,\N,missense_variant,26.9,0.00110132,EXAC_OTH_AF,TSPEAR
503457,21:45947218:G>C,NM_144991.2:c.1106C>G,NP_659428.2:p.Thr369Arg,7/12,\N,Unknown significance,\N,missense_variant,26.4,\N,\N,TSPEAR
503458,21:45947218:G>T,NM_144991.2:c.1106C>A,NP_659428.2:p.Thr369Lys,7/12,\N,Unknown significance,\N,missense_variant,28.3,0.0000149871,EXAC_NFE_AF,TSPEAR
503459,21:45947219:T>TG,NM_144991.2:c.1104dup,NP_659428.2:p.Thr369HisfsTer22,7/12,\N,Unknown significance,\N,frameshift_variant,\N,\N,\N,TSPEAR
503460,21:45947223:G>C,NM_144991.2:c.1101C>G,NP_659428.2:p.Ile367Met,7/12,\N,Unknown significance,\N,missense_variant,21.9,0.0000149867,EXAC_NFE_AF,TSPEAR
503461,21:45947227:T>C,NM_144991.2:c.1097A>G,NP_659428.2:p.Asn366Ser,7/12,\N,Likely benign,\N,missense_variant,0.003,0.0000149867,EXAC_NFE_AF,TSPEAR
503462,21:45947229:C>G,NM_144991.2:c.1095G>C,NP_659428.2:p.Gln365His,7/12,\N,Unknown significance,\N,missense_variant,23.7,0.000116279,EVS_EA_AF,TSPEAR
503463,21:45947231:G>C,NM_144991.2:c.1093C>G,NP_659428.2:p.Gln365Glu,7/12,\N,Unknown significance,\N,missense_variant,23.5,0.000060562,EXAC_SAS_AF,TSPEAR
503464,21:45947232:A>T,NM_144991.2:c.1092T>A,NP_659428.2:p.Tyr364Ter,7/12,\N,Unknown significance,\N,stop_gained,29.9,0.0000149862,EXAC_NFE_AF,TSPEAR
503465,21:45947235:T>G,NM_144991.2:c.1089A>C,NP_659428.2:p.Ser363=,7/12,\N,Unknown significance,\N,synonymous_variant,0.017,0.000060562,EXAC_SAS_AF,TSPEAR
503466,21:45947240:C>T,NM_144991.2:c.1084G>A,NP_659428.2:p.Val362Ile,7/12,\N,Likely benign,\N,missense_variant,6.991,0.0015,1KG_AFR_AF,TSPEAR
503467,21:45947241:G>A,NM_144991.2:c.1083C>T,NP_659428.2:p.Phe361=,7/12,\N,Unknown significance,\N,synonymous_variant,7.353,0.000172741,EXAC_AMR_AF,TSPEAR
503468,21:45947245:T>C,NM_144991.2:c.1079A>G,NP_659428.2:p.Lys360Arg,7/12,\N,Unknown significance,\N,missense_variant,2.932,0.000116279,EVS_EA_AF,TSPEAR
503469,21:45947252:C>T,NM_144991.2:c.1072G>A,NP_659428.2:p.Glu358Lys,7/12,\N,Likely benign,\N,missense_variant,11.9,0.000232558,EVS_EA_AF,TSPEAR
503470,21:45947252:CG>C,NM_144991.2:c.1071del,NP_659428.2:p.Glu358LysfsTer54,7/12,\N,Unknown significance,\N,frameshift_variant,13.53,0.0000449586,EXAC_NFE_AF,TSPEAR
503471,21:45947252:C>G,NM_144991.2:c.1072G>C,NP_659428.2:p.Glu358Gln,7/12,\N,Likely benign,\N,missense_variant,9.015,0.0000149862,EXAC_NFE_AF,TSPEAR
503472,21:45947253:G>A,NM_144991.2:c.1071C>T,NP_659428.2:p.Thr357=,7/12,\N,Unknown significance,\N,synonymous_variant,5.15,0.0008,1KG_AFR_AF,TSPEAR
503473,21:45947258:AC>A,NM_144991.2:c.1065del,NP_659428.2:p.Lys355AsnfsTer57,7/12,\N,Unknown significance,\N,frameshift_variant,25.1,\N,\N,TSPEAR
503474,21:45947263:T>G,NM_144991.2:c.1061A>C,NP_659428.2:p.Tyr354Ser,7/12,\N,Unknown significance,\N,missense_variant,24.7,0.0000961169,EXAC_AFR_AF,TSPEAR
503475,21:45947264:A>C,NM_144991.2:c.1060T>G,NP_659428.2:p.Tyr354Asp,7/12,\N,Unknown significance,\N,missense_variant,24.5,0.0000149862,EXAC_NFE_AF,TSPEAR
503476,21:45947267:C>T,NM_144991.2:c.1057G>A,NP_659428.2:p.Val353Ile,7/12,\N,Likely benign,\N,missense_variant,0.309,0.00127109,EXAC_EAS_AF,TSPEAR
503477,21:45947268:G>A,NM_144991.2:c.1056C>T,NP_659428.2:p.Ala352=,7/12,\N,Unknown significance,\N,synonymous_variant,6.696,0.00103998,EXAC_EAS_AF,TSPEAR
503478,21:45947270:C>T,NM_144991.2:c.1054G>A,NP_659428.2:p.Ala352Thr,7/12,\N,Likely benign,\N,missense_variant,10.78,0.002,1KG_SAS_AF,TSPEAR
503479,21:45947271:G>A,NM_144991.2:c.1053C>T,NP_659428.2:p.Ser351=,7/12,\N,Unknown significance,\N,synonymous_variant,6.971,0.0000960984,EXAC_AFR_AF,TSPEAR
503480,21:45947273:A>G,NM_144991.2:c.1051T>C,NP_659428.2:p.Ser351Pro,7/12,\N,Unknown significance,\N,missense_variant,24.5,0.000181686,EXAC_SAS_AF,TSPEAR
503481,21:45947276:T>C,NM_144991.2:c.1048A>G,NP_659428.2:p.Thr350Ala,7/12,\N,Likely benign,\N,missense_variant,0.117,0.000060562,EXAC_SAS_AF,TSPEAR
503482,21:45947277:G>T,NM_144991.2:c.1047C>A,NP_659428.2:p.Ala349=,7/12,\N,Unknown significance,\N,synonymous_variant,0.786,0.0000149867,EXAC_NFE_AF,TSPEAR
503483,21:45947278:G>T,NM_144991.2:c.1046C>A,NP_659428.2:p.Ala349Asp,7/12,\N,Unknown significance,\N,missense_variant,9.51,0.0000149876,EXAC_NFE_AF,TSPEAR
503484,21:45947281:T>C,NM_144991.2:c.1043A>G,NP_659428.2:p.Lys348Arg,7/12,\N,Likely benign,\N,missense_variant,0.036,0.001,1KG_SAS_AF,TSPEAR
503485,21:45947283:G>A,NM_144991.2:c.1041C>T,NP_659428.2:p.Arg347=,7/12,\N,Unknown significance,\N,synonymous_variant,0.342,0.0000149876,EXAC_NFE_AF,TSPEAR
503486,21:45947284:C>T,NM_144991.2:c.1040G>A,NP_659428.2:p.Arg347His,7/12,\N,Unknown significance,\N,missense_variant,22.7,0.000060562,EXAC_SAS_AF,TSPEAR
503487,21:45947285:G>T,NM_144991.2:c.1039C>A,NP_659428.2:p.Arg347Ser,7/12,\N,Benign,\N,missense_variant,21.9,0.0112,1KG_SAS_AF,TSPEAR
503488,21:45947287:T>C,NM_144991.2:c.1037A>G,NP_659428.2:p.Asn346Ser,7/12,\N,Unknown significance,\N,missense_variant,19.46,0.000121124,EXAC_SAS_AF,TSPEAR
503489,21:45947292:T>TG,NM_144991.2:c.1031dup,NP_659428.2:p.Ala345SerfsTer46,7/12,\N,Unknown significance,\N,frameshift_variant,\N,\N,\N,TSPEAR
503490,21:45947301:A>T,NM_144991.2:c.1023T>A,NP_659428.2:p.Phe341Leu,7/12,\N,Unknown significance,\N,missense_variant,10.61,0.000172741,EXAC_AMR_AF,TSPEAR
503491,21:45947305:A>G,NM_144991.2:c.1019T>C,NP_659428.2:p.Leu340Pro,7/12,\N,Unknown significance,\N,missense_variant,24.5,0.0014,1KG_AMR_AF,TSPEAR
503492,21:45947307:C>T,NM_144991.2:c.1017G>A,NP_659428.2:p.Gly339=,7/12,\N,Unknown significance,\N,synonymous_variant,8.557,0.00060562,EXAC_SAS_AF,TSPEAR
503493,21:45947311:A>C,NM_144991.2:c.1013T>G,NP_659428.2:p.Val338Gly,7/12,\N,Unknown significance,\N,missense_variant,11.98,0.0000961354,EXAC_AFR_AF,TSPEAR
503494,21:45947315:G>T,NM_144991.2:c.1009C>A,NP_659428.2:p.Gln337Lys,7/12,\N,Likely benign,\N,missense_variant,0.002,0.0000149862,EXAC_NFE_AF,TSPEAR
503495,21:45947319:G>A,NM_144991.2:c.1005C>T,NP_659428.2:p.Ile335=,7/12,\N,Unknown significance,\N,synonymous_variant,4.835,0.0000961538,EXAC_AFR_AF,TSPEAR
503496,21:45947321:T>G,NM_144991.2:c.1003A>C,NP_659428.2:p.Ile335Leu,7/12,\N,Unknown significance,\N,missense_variant,23.1,0.0000149862,EXAC_NFE_AF,TSPEAR
503497,21:45947324:G>A,NM_144991.2:c.1000C>T,NP_659428.2:p.Arg334Cys,7/12,\N,Likely benign,\N,missense_variant,18.55,0.000060562,EXAC_SAS_AF,TSPEAR
503498,21:45947335:A>G,NM_144991.2:c.989T>C,NP_659428.2:p.Ile330Thr,7/12,\N,Unknown significance,\N,missense_variant,24.8,0.000060562,EXAC_SAS_AF,TSPEAR
503499,21:45947340:C>T,NM_144991.2:c.984G>A,NP_659428.2:p.Leu328=,7/12,\N,Unknown significance,\N,synonymous_variant,10.69,0.00110132,EXAC_OTH_AF,TSPEAR
503500,21:45947345:T>G,NM_144991.2:c.979A>C,NP_659428.2:p.Thr327Pro,7/12,\N,Unknown significance,\N,missense_variant,25.4,0.00110132,EXAC_OTH_AF,TSPEAR
503501,21:45947346:C>G,NM_144991.2:c.978G>C,NP_659428.2:p.Glu326Asp,7/12,\N,Unknown significance,\N,missense_variant,23.2,0.000116279,EVS_EA_AF,TSPEAR
503502,21:45947355:G>C,NM_144991.2:c.969C>G,NP_659428.2:p.Thr323=,7/12,\N,Unknown significance,\N,synonymous_variant,0.062,0.000014988,EXAC_NFE_AF,TSPEAR
503503,21:45947357:T>C,NM_144991.2:c.967A>G,NP_659428.2:p.Thr323Ala,7/12,\N,Unknown significance,\N,missense_variant,23.6,0.000151194,EXAC_FIN_AF,TSPEAR
503504,21:45947366:T>C,NM_144991.2:c.958A>G,NP_659428.2:p.Asn320Asp,7/12,\N,Likely benign,\N,missense_variant,0.001,0.0000149876,EXAC_NFE_AF,TSPEAR
503505,21:45947369:G>C,NM_144991.2:c.955C>G,NP_659428.2:p.Gln319Glu,7/12,\N,Unknown significance,\N,missense_variant,21.9,0.000363372,EXAC_SAS_AF,TSPEAR
503506,21:45947381:C>T,NM_144991.2:c.943G>A,NP_659428.2:p.Val315Met,7/12,\N,Unknown significance,\N,missense_variant,27.2,0.00340445,EVS_AA_AF,TSPEAR
503507,21:45947382:G>A,NM_144991.2:c.942C>T,NP_659428.2:p.Tyr314=,7/12,\N,Unknown significance,\N,synonymous_variant,2.473,0.000134933,EXAC_NFE_AF,TSPEAR
503508,21:45947384:A>G,NM_144991.2:c.940T>C,NP_659428.2:p.Tyr314His,7/12,\N,Unknown significance,\N,missense_variant,25.2,0.000151194,EXAC_FIN_AF,TSPEAR
503509,21:45947387:C>A,NM_144991.2:c.937G>T,NP_659428.2:p.Asp313Tyr,7/12,\N,Unknown significance,\N,missense_variant,27.3,0.0000864006,EXAC_AMR_AF,TSPEAR
503510,21:45947415:C>CGTTGTG,NM_144991.2:c.923-20_923-15dup,\N,\N,6/11,Unknown significance,\N,intron_variant,4.776,0.000192938,EXAC_AFR_AF,TSPEAR
503511,21:45947415:C>T,NM_144991.2:c.923-14G>A,\N,\N,6/11,Unknown significance,\N,intron_variant,2.476,0.000115714,EXAC_EAS_AF,TSPEAR
503512,21:45947416:G>A,NM_144991.2:c.923-15C>T,\N,\N,6/11,Unknown significance,\N,intron_variant,3.751,0.000116279,EVS_EA_AF,TSPEAR
503513,21:45947417:T>C,NM_144991.2:c.923-16A>G,\N,\N,6/11,Unknown significance,\N,intron_variant,2.797,0.0000605694,EXAC_SAS_AF,TSPEAR
503514,21:45947418:T>C,NM_144991.2:c.923-17A>G,\N,\N,6/11,Benign,\N,intron_variant,1.328,0.0098,1KG_AFR_AF,TSPEAR
503515,21:45947420:T>A,NM_144991.2:c.923-19A>T,\N,\N,6/11,Unknown significance,\N,intron_variant,3.195,0.0000150267,EXAC_NFE_AF,TSPEAR
503516,21:45947422:A>C,NM_144991.2:c.923-21T>G,\N,\N,6/11,Unknown significance,\N,intron_variant,1.805,0.0000605767,EXAC_SAS_AF,TSPEAR
503517,21:45947425:C>T,NM_144991.2:c.923-24G>A,\N,\N,6/11,Unknown significance,\N,intron_variant,4.045,0.000453926,EVS_AA_AF,TSPEAR
503518,21:45947426:G>A,NM_144991.2:c.923-25C>T,\N,\N,6/11,Unknown significance,\N,intron_variant,2.085,0.001,1KG_EUR_AF,TSPEAR
503519,21:45947427:G>T,NM_144991.2:c.923-26C>A,\N,\N,6/11,Unknown significance,\N,intron_variant,3.198,0.000060584,EXAC_SAS_AF,TSPEAR
503520,21:45947438:C>T,NM_144991.2:c.923-37G>A,\N,\N,6/11,Unknown significance,\N,intron_variant,0.504,0.0000966931,EXAC_AFR_AF,TSPEAR
503521,21:45947439:G>A,NM_144991.2:c.923-38C>T,\N,\N,6/11,Unknown significance,\N,intron_variant,1.32,0.0008,1KG_AFR_AF,TSPEAR
503522,21:45947444:C>T,NM_144991.2:c.923-43G>A,\N,\N,6/11,Unknown significance,\N,intron_variant,0.796,0.0000867604,EXAC_AMR_AF,TSPEAR
503523,21:45947445:G>A,NM_144991.2:c.923-44C>T,\N,\N,6/11,Unknown significance,\N,intron_variant,2.986,0.000465766,EXAC_EAS_AF,TSPEAR
503524,21:45947446:G>A,NM_144991.2:c.923-45C>T,\N,\N,6/11,Unknown significance,\N,intron_variant,4.592,0.0000606575,EXAC_SAS_AF,TSPEAR
503525,21:45947451:C>T,NM_144991.2:c.923-50G>A,\N,\N,6/11,Unknown significance,\N,intron_variant,6.325,0.00111607,EXAC_OTH_AF,TSPEAR
503526,21:45947452:C>T,NM_144991.2:c.923-51G>A,\N,\N,6/11,Unknown significance,\N,intron_variant,0.95,0.0000608495,EXAC_SAS_AF,TSPEAR
503527,21:45947453:A>G,NM_144991.2:c.923-52T>C,\N,\N,6/11,Unknown significance,\N,intron_variant,0.672,0.0000607607,EXAC_SAS_AF,TSPEAR
503528,21:45947465:G>A,NM_144991.2:c.923-64C>T,\N,\N,6/11,Unknown significance,\N,intron_variant,0.587,\N,\N,TSPEAR
503529,21:45947467:G>A,NM_144991.2:c.923-66C>T,\N,\N,6/11,Benign,\N,intron_variant,3.095,0.0787,1KG_AFR_AF,TSPEAR
503530,21:45947472:C>A,NM_144991.2:c.923-71G>T,\N,\N,6/11,Unknown significance,\N,intron_variant,3.941,\N,\N,TSPEAR
503531,21:45947487:C>T,NM_144991.2:c.923-86G>A,\N,\N,6/11,Unknown significance,\N,intron_variant,6.1,0.0014,1KG_AMR_AF,TSPEAR
503532,21:45947498:G>A,NM_144991.2:c.923-97C>T,\N,\N,6/11,Unknown significance,\N,intron_variant,4.671,0.0014,1KG_AMR_AF,TSPEAR
503533,21:45947502:C>T,NM_144991.2:c.923-101G>A,\N,\N,6/11,Unknown significance,\N,intron_variant,0.135,\N,\N,TSPEAR
503534,21:45947503:G>A,NM_144991.2:c.923-102C>T,\N,\N,6/11,Unknown significance,\N,intron_variant,3.141,0.002,1KG_SAS_AF,TSPEAR
503535,21:45947511:C>T,NM_144991.2:c.923-110G>A,\N,\N,6/11,Unknown significance,\N,intron_variant,1.879,0.001,1KG_EUR_AF|1KG_SAS_AF,TSPEAR
503536,21:45947512:G>A,NM_144991.2:c.923-111C>T,\N,\N,6/11,Unknown significance,\N,intron_variant,3.586,\N,\N,TSPEAR
503537,21:45947531:G>A,NM_144991.2:c.923-130C>T,\N,\N,6/11,Unknown significance,\N,intron_variant,3.829,0.0008,1KG_AFR_AF,TSPEAR
503538,21:45947538:C>T,NM_144991.2:c.923-137G>A,\N,\N,6/11,Unknown significance,\N,intron_variant,3.042,0.001,1KG_EAS_AF,TSPEAR
503539,21:45947539:G>A,NM_144991.2:c.923-138C>T,\N,\N,6/11,Unknown significance,\N,intron_variant,2.416,0.001,1KG_SAS_AF,TSPEAR
503540,21:45947543:C>T,NM_144991.2:c.923-142G>A,\N,\N,6/11,Unknown significance,\N,intron_variant,2.006,\N,\N,TSPEAR
503541,21:45947570:G>A,NM_144991.2:c.923-169C>T,\N,\N,6/11,Unknown significance,\N,intron_variant,5.465,\N,\N,TSPEAR
503542,21:45947639:T>C,NM_144991.2:c.923-238A>G,\N,\N,6/11,Unknown significance,\N,intron_variant,2.192,0.0014,1KG_AMR_AF,TSPEAR
503543,21:45947684:T>C,NM_144991.2:c.923-283A>G,\N,\N,6/11,Benign,\N,intron_variant,1.426,0.3956,1KG_AFR_AF,TSPEAR
503544,21:45947688:G>A,NM_144991.2:c.923-287C>T,\N,\N,6/11,Unknown significance,\N,intron_variant,3.599,0.001,1KG_EAS_AF,TSPEAR
503545,21:45947702:G>C,NM_144991.2:c.923-301C>G,\N,\N,6/11,Unknown significance,\N,intron_variant,1.125,0.001,1KG_SAS_AF,TSPEAR
503546,21:45947716:C>T,NM_144991.2:c.923-315G>A,\N,\N,6/11,Unknown significance,\N,intron_variant,0.118,\N,\N,TSPEAR
503547,21:45947717:G>A,NM_144991.2:c.923-316C>T,\N,\N,6/11,Unknown significance,\N,intron_variant,3.066,0.001,1KG_EUR_AF,TSPEAR
503548,21:45947725:C>T,NM_144991.2:c.923-324G>A,\N,\N,6/11,Unknown significance,\N,intron_variant,0.854,\N,\N,TSPEAR
503549,21:45947731:C>T,NM_144991.2:c.923-330G>A,\N,\N,6/11,Benign,\N,intron_variant,3.35,0.0149,1KG_EAS_AF,TSPEAR
503550,21:45947747:C>T,NM_144991.2:c.923-346G>A,\N,\N,6/11,Unknown significance,\N,intron_variant,1.243,0.001,1KG_EUR_AF,TSPEAR
503551,21:45947787:C>T,NM_144991.2:c.923-386G>A,\N,\N,6/11,Unknown significance,\N,intron_variant,6.603,\N,\N,TSPEAR
503552,21:45947805:C>T,NM_144991.2:c.923-404G>A,\N,\N,6/11,Unknown significance,\N,intron_variant,3.593,\N,\N,TSPEAR
503553,21:45947806:G>A,NM_144991.2:c.923-405C>T,\N,\N,6/11,Unknown significance,\N,intron_variant,0.828,\N,\N,TSPEAR
503554,21:45947821:C>G,NM_144991.2:c.923-420G>C,\N,\N,6/11,Benign,\N,intron_variant,2.689,0.1694,1KG_AFR_AF,TSPEAR
503555,21:45947837:C>A,NM_144991.2:c.923-436G>T,\N,\N,6/11,Unknown significance,\N,intron_variant,5.66,0.002,1KG_SAS_AF,TSPEAR
503556,21:45947849:G>T,NM_144991.2:c.923-448C>A,\N,\N,6/11,Benign,\N,intron_variant,0.957,0.1785,1KG_AFR_AF,TSPEAR
503557,21:45947896:G>A,NM_144991.2:c.922+439C>T,\N,\N,6/11,Unknown significance,\N,intron_variant,4.716,\N,\N,TSPEAR
503558,21:45947905:C>T,NM_144991.2:c.922+430G>A,\N,\N,6/11,Benign,\N,intron_variant,0.531,0.0083,1KG_AFR_AF,TSPEAR
503559,21:45947912:C>T,NM_144991.2:c.922+423G>A,\N,\N,6/11,Unknown significance,\N,intron_variant,3.098,\N,\N,TSPEAR
503560,21:45947940:G>A,NM_144991.2:c.922+395C>T,\N,\N,6/11,Unknown significance,\N,intron_variant,3.477,\N,\N,TSPEAR
503561,21:45947975:G>T,NM_144991.2:c.922+360C>A,\N,\N,6/11,Benign,\N,intron_variant,2.289,0.1331,1KG_AFR_AF,TSPEAR
503562,21:45947984:G>A,NM_144991.2:c.922+351C>T,\N,\N,6/11,Unknown significance,\N,intron_variant,3.318,0.001,1KG_SAS_AF,TSPEAR
503563,21:45947994:C>T,NM_144991.2:c.922+341G>A,\N,\N,6/11,Unknown significance,\N,intron_variant,8.817,0.001,1KG_SAS_AF,TSPEAR
503564,21:45948054:G>A,NM_144991.2:c.922+281C>T,\N,\N,6/11,Benign,\N,intron_variant,1.326,0.0681,1KG_AFR_AF,TSPEAR
503565,21:45948054:G>T,NM_144991.2:c.922+281C>A,\N,\N,6/11,Unknown significance,\N,intron_variant,0.531,\N,\N,TSPEAR
503566,21:45948071:A>G,NM_144991.2:c.922+264T>C,\N,\N,6/11,Benign,\N,intron_variant,1.445,0.3548,1KG_AFR_AF,TSPEAR
503567,21:45948072:G>C,NM_144991.2:c.922+263C>G,\N,\N,6/11,Unknown significance,\N,intron_variant,0.248,0.0014,1KG_AMR_AF,TSPEAR
503568,21:45948118:A>G,NM_144991.2:c.922+217T>C,\N,\N,6/11,Unknown significance,\N,intron_variant,0.7,0.001,1KG_EAS_AF,TSPEAR
503569,21:45948137:G>A,NM_144991.2:c.922+198C>T,\N,\N,6/11,Unknown significance,\N,intron_variant,2.952,0.001,1KG_EAS_AF,TSPEAR
503570,21:45948185:C>T,NM_144991.2:c.922+150G>A,\N,\N,6/11,Unknown significance,\N,intron_variant,4.53,\N,\N,TSPEAR
503571,21:45948191:A>C,NM_144991.2:c.922+144T>G,\N,\N,6/11,Unknown significance,\N,intron_variant,1.362,0.0015,1KG_AFR_AF,TSPEAR
503572,21:45948242:G>A,NM_144991.2:c.922+93C>T,\N,\N,6/11,Unknown significance,\N,intron_variant,7.43,\N,\N,TSPEAR
503573,21:45948243:G>T,NM_144991.2:c.922+92C>A,\N,\N,6/11,Unknown significance,\N,intron_variant,5.134,\N,\N,TSPEAR
503574,21:45948281:C>T,NM_144991.2:c.922+54G>A,\N,\N,6/11,Benign,\N,intron_variant,1.158,0.1687,1KG_AFR_AF,TSPEAR
503575,21:45948287:G>A,NM_144991.2:c.922+48C>T,\N,\N,6/11,Unknown significance,\N,intron_variant,3.241,0.000181708,EXAC_SAS_AF,TSPEAR
503576,21:45948288:C>CCAGAGTGGGCCCGACTGGGGCGGGCTG,NM_144991.2:c.922+46_922+47insCAGCCCGCCCCAGTCGGGCCCACTCTG,\N,\N,6/11,Unknown significance,\N,intron_variant,0.339,\N,\N,TSPEAR
503577,21:45948292:A>G,NM_144991.2:c.922+43T>C,\N,\N,6/11,Unknown significance,\N,intron_variant,0.046,0.001,1KG_EAS_AF,TSPEAR
503578,21:45948296:GC>G,NM_144991.2:c.922+38del,\N,\N,6/11,Unknown significance,\N,intron_variant,3,0.0000963948,EXAC_AFR_AF,TSPEAR
503579,21:45948298:C>G,NM_144991.2:c.922+37G>C,\N,\N,6/11,Unknown significance,\N,intron_variant,2.932,0.000096432,EXAC_AFR_AF,TSPEAR
503580,21:45948299:CTGCA>C,NM_144991.2:c.922+32_922+35del,\N,\N,6/11,Unknown significance,\N,intron_variant,3.883,0.000545124,EXAC_SAS_AF,TSPEAR
503581,21:45948307:C>T,NM_144991.2:c.922+28G>A,\N,\N,6/11,Unknown significance,\N,intron_variant,2.593,0.000116279,EVS_EA_AF,TSPEAR
503582,21:45948309:A>G,NM_144991.2:c.922+26T>C,\N,\N,6/11,Unknown significance,\N,intron_variant,4.534,0.0000150476,EXAC_NFE_AF,TSPEAR
503583,21:45948310:C>T,NM_144991.2:c.922+25G>A,\N,\N,6/11,Unknown significance,\N,intron_variant,0.935,0.000151194,EXAC_FIN_AF,TSPEAR
503584,21:45948311:G>A,NM_144991.2:c.922+24C>T,\N,\N,6/11,Unknown significance,\N,intron_variant,3.257,0.000115794,EXAC_EAS_AF,TSPEAR
503585,21:45948315:C>T,NM_144991.2:c.922+20G>A,\N,\N,6/11,Unknown significance,\N,intron_variant,8.762,0.00110619,EXAC_OTH_AF,TSPEAR
503586,21:45948316:G>A,NM_144991.2:c.922+19C>T,\N,\N,6/11,Unknown significance,\N,intron_variant,8.613,0.000115768,EXAC_EAS_AF,TSPEAR
503587,21:45948318:G>T,NM_144991.2:c.922+17C>A,\N,\N,6/11,Unknown significance,\N,intron_variant,6.661,0.0008,1KG_AFR_AF,TSPEAR
503588,21:45948326:C>A,NM_144991.2:c.922+9G>T,\N,\N,6/11,Unknown significance,\N,intron_variant,10.7,0.0000150313,EXAC_NFE_AF,TSPEAR
503589,21:45948342:C>T,NM_144991.2:c.915G>A,NP_659428.2:p.Val305=,6/12,\N,Unknown significance,\N,synonymous_variant,11.17,0.0000600691,EXAC_NFE_AF,TSPEAR
503590,21:45948345:G>A,NM_144991.2:c.912C>T,NP_659428.2:p.Ser304=,6/12,\N,Unknown significance,\N,synonymous_variant,11.18,0.0000961908,EXAC_AFR_AF,TSPEAR
503591,21:45948347:A>T,NM_144991.2:c.910T>A,NP_659428.2:p.Ser304Thr,6/12,\N,Unknown significance,\N,missense_variant,2.025,0.000121124,EXAC_SAS_AF,TSPEAR
503592,21:45948356:C>T,NM_144991.2:c.901G>A,NP_659428.2:p.Glu301Lys,6/12,\N,Likely benign,\N,missense_variant,0.269,0.0015,1KG_AFR_AF,TSPEAR
503593,21:45948357:G>A,NM_144991.2:c.900C>T,NP_659428.2:p.Asn300=,6/12,\N,Unknown significance,\N,synonymous_variant,5.3,0.00480954,EXAC_AFR_AF,TSPEAR
503594,21:45948357:G>C,NM_144991.2:c.900C>G,NP_659428.2:p.Asn300Lys,6/12,\N,Likely benign,\N,missense_variant,0.016,0.0000150119,EXAC_NFE_AF,TSPEAR
503595,21:45948364:A>G,NM_144991.2:c.893T>C,NP_659428.2:p.Val298Ala,6/12,\N,Likely benign,\N,missense_variant,2.195,0.00113482,EVS_AA_AF,TSPEAR
503596,21:45948364:A>T,NM_144991.2:c.893T>A,NP_659428.2:p.Val298Asp,6/12,\N,Likely benign,\N,missense_variant,0.395,0.0000961908,EXAC_AFR_AF,TSPEAR
503597,21:45948365:C>A,NM_144991.2:c.892G>T,NP_659428.2:p.Val298Phe,6/12,\N,Unknown significance,\N,missense_variant,20.2,0.0023,1KG_AFR_AF,TSPEAR
503598,21:45948365:C>T,NM_144991.2:c.892G>A,NP_659428.2:p.Val298Ile,6/12,\N,Likely benign,\N,missense_variant,9.666,0.0000961908,EXAC_AFR_AF,TSPEAR
503599,21:45948371:G>T,NM_144991.2:c.886C>A,NP_659428.2:p.Leu296Met,6/12,\N,Unknown significance,\N,missense_variant,21.6,0.000346741,EXAC_EAS_AF,TSPEAR
503600,21:45948375:C>T,NM_144991.2:c.882G>A,NP_659428.2:p.Leu294=,6/12,\N,Unknown significance,\N,synonymous_variant,9.854,0.0000150078,EXAC_NFE_AF,TSPEAR
503601,21:45948379:C>T,NM_144991.2:c.878G>A,NP_659428.2:p.Gly293Asp,6/12,\N,Unknown significance,\N,missense_variant,19.57,0.0000864155,EXAC_AMR_AF,TSPEAR
503602,21:45948385:C>T,NM_144991.2:c.872G>A,NP_659428.2:p.Arg291Gln,6/12,\N,Benign,\N,missense_variant,12.58,0.006,1KG_EAS_AF,TSPEAR
503603,21:45948386:G>A,NM_144991.2:c.871C>T,NP_659428.2:p.Arg291Trp,6/12,\N,Unknown significance,\N,missense_variant,24.1,0.0008,1KG_AFR_AF,TSPEAR
503604,21:45948397:A>G,NM_144991.2:c.860T>C,NP_659428.2:p.Phe287Ser,6/12,\N,Unknown significance,\N,missense_variant,27.3,0.000060562,EXAC_SAS_AF,TSPEAR
503605,21:45948400:C>G,NM_144991.2:c.857G>C,NP_659428.2:p.Trp286Ser,6/12,\N,Unknown significance,\N,missense_variant,28.9,0.00110375,EXAC_OTH_AF,TSPEAR
503606,21:45948402:G>A,NM_144991.2:c.855C>T,NP_659428.2:p.Phe285=,6/12,\N,Unknown significance,\N,synonymous_variant,10.3,0.0000150074,EXAC_NFE_AF,TSPEAR
503607,21:45948410:C>T,NM_144991.2:c.847G>A,NP_659428.2:p.Ala283Thr,6/12,\N,Unknown significance,\N,missense_variant,24.6,0.0000150096,EXAC_NFE_AF,TSPEAR
503608,21:45948416:C>T,NM_144991.2:c.841G>A,NP_659428.2:p.Glu281Lys,6/12,\N,Unknown significance,\N,missense_variant,12.61,0.000242248,EXAC_SAS_AF,TSPEAR
503609,21:45948417:C>T,NM_144991.2:c.840G>A,NP_659428.2:p.Val280=,6/12,\N,Unknown significance,\N,synonymous_variant,5.856,0.000288739,EXAC_AFR_AF,TSPEAR
503610,21:45948422:C>T,NM_144991.2:c.835G>A,NP_659428.2:p.Glu279Lys,6/12,\N,Likely benign,\N,missense_variant,0.144,0.000060562,EXAC_SAS_AF,TSPEAR
503611,21:45948423:G>A,NM_144991.2:c.834C>T,NP_659428.2:p.Thr278=,6/12,\N,Unknown significance,\N,synonymous_variant,7.185,0.000135164,EXAC_NFE_AF,TSPEAR
503612,21:45948424:G>T,NM_144991.2:c.833C>A,NP_659428.2:p.Thr278Asn,6/12,\N,Unknown significance,\N,missense_variant,23.5,0.0000150173,EXAC_NFE_AF,TSPEAR
503613,21:45948429:C>T,NM_144991.2:c.828G>A,NP_659428.2:p.Pro276=,6/12,\N,Unknown significance,\N,synonymous_variant,10.97,0.000288906,EXAC_AFR_AF,TSPEAR
503614,21:45948430:G>A,NM_144991.2:c.827C>T,NP_659428.2:p.Pro276Leu,6/12,\N,Unknown significance,\N,missense_variant,8.434,0.0000300526,EXAC_NFE_AF,TSPEAR
503615,21:45948443:C>T,NM_144991.2:c.814G>A,NP_659428.2:p.Gly272Arg,6/12,\N,Unknown significance,\N,missense_variant,27.7,\N,\N,TSPEAR
503616,21:45948445:A>C,NM_144991.2:c.812T>G,NP_659428.2:p.Leu271Arg,6/12,\N,Unknown significance,\N,missense_variant,24.6,0.00034638,EXAC_AMR_AF,TSPEAR
503617,21:45948447:C>T,NM_144991.2:c.810G>A,NP_659428.2:p.Thr270=,6/12,\N,Unknown significance,\N,synonymous_variant,11.62,0.0014,1KG_AMR_AF,TSPEAR
503618,21:45948448:G>A,NM_144991.2:c.809C>T,NP_659428.2:p.Thr270Met,6/12,\N,Unknown significance,\N,missense_variant,26.9,0.0041,1KG_SAS_AF,TSPEAR
503619,21:45948449:T>TC,NM_144991.2:c.807dup,NP_659428.2:p.Thr270AspfsTer19,6/12,\N,Unknown significance,\N,frameshift_variant,32,0.0000150494,EXAC_NFE_AF,TSPEAR
503620,21:45948450:C>T,NM_144991.2:c.807G>A,NP_659428.2:p.Val269=,6/12,\N,Unknown significance,\N,synonymous_variant,7.85,0.000226963,EVS_AA_AF,TSPEAR
503621,21:45948454:C>T,NM_144991.2:c.803G>A,NP_659428.2:p.Arg268Gln,6/12,\N,Likely benign,\N,missense_variant,15.94,\N,\N,TSPEAR
503622,21:45948455:G>A,NM_144991.2:c.802C>T,NP_659428.2:p.Arg268Ter,6/12,\N,Unknown significance,\N,stop_gained,35,0.0000150611,EXAC_NFE_AF,TSPEAR
503623,21:45948458:T>C,NM_144991.2:c.799A>G,NP_659428.2:p.Ile267Val,6/12,\N,Likely benign,\N,missense_variant,0.001,\N,\N,TSPEAR
503624,21:45948463:G>A,NM_144991.2:c.794C>T,NP_659428.2:p.Thr265Ile,6/12,\N,Unknown significance,\N,missense_variant,13.39,0.000232234,EXAC_EAS_AF,TSPEAR
503625,21:45948469:G>A,NM_144991.2:c.791-3C>T,\N,\N,5/11,Unknown significance,\N,splice_region_variant&intron_variant,8.878,0.0000151304,EXAC_NFE_AF,TSPEAR
503626,21:45948470:AG>A,NM_144991.2:c.791-5del,\N,\N,5/11,Unknown significance,\N,splice_region_variant&intron_variant,1.438,0.000232666,EXAC_EAS_AF,TSPEAR
503627,21:45948477:G>C,NM_144991.2:c.791-11C>G,\N,\N,5/11,Unknown significance,\N,intron_variant,4.374,0.0000759025,EXAC_NFE_AF,TSPEAR
503628,21:45948480:C>G,NM_144991.2:c.791-14G>C,\N,\N,5/11,Unknown significance,\N,intron_variant,3.6,0.000813953,EVS_EA_AF,TSPEAR
503629,21:45948488:T>C,NM_144991.2:c.791-22A>G,\N,\N,5/11,Unknown significance,\N,intron_variant,2.988,0.0000152495,EXAC_NFE_AF,TSPEAR
503630,21:45948494:T>A,NM_144991.2:c.791-28A>T,\N,\N,5/11,Unknown significance,\N,intron_variant,6.672,0.0000152961,EXAC_NFE_AF,TSPEAR
503631,21:45948507:T>C,NM_144991.2:c.791-41A>G,\N,\N,5/11,Unknown significance,\N,intron_variant,3.112,\N,\N,TSPEAR
503632,21:45948508:G>A,NM_144991.2:c.791-42C>T,\N,\N,5/11,Unknown significance,\N,intron_variant,4.701,0.0000882457,EXAC_AMR_AF,TSPEAR
503633,21:45948509:C>T,NM_144991.2:c.791-43G>A,\N,\N,5/11,Unknown significance,\N,intron_variant,4.412,0.0014,1KG_AMR_AF,TSPEAR
503634,21:45948513:C>G,NM_144991.2:c.791-47G>C,\N,\N,5/11,Unknown significance,\N,intron_variant,0.864,0.0000620444,EXAC_NFE_AF,TSPEAR
503635,21:45948523:C>T,NM_144991.2:c.791-57G>A,\N,\N,5/11,Benign,\N,intron_variant,0.758,0.1762,1KG_AFR_AF,TSPEAR
503636,21:45948530:G>C,NM_144991.2:c.791-64C>G,\N,\N,5/11,Benign,\N,intron_variant,0.877,0.0408,1KG_AFR_AF,TSPEAR
503637,21:45948572:A>C,NM_144991.2:c.791-106T>G,\N,\N,5/11,Unknown significance,\N,intron_variant,1.411,0.0008,1KG_AFR_AF,TSPEAR
503638,21:45948617:C>T,NM_144991.2:c.791-151G>A,\N,\N,5/11,Unknown significance,\N,intron_variant,2.555,\N,\N,TSPEAR
503639,21:45948629:C>T,NM_144991.2:c.791-163G>A,\N,\N,5/11,Benign,\N,intron_variant,0.125,0.0636,1KG_EUR_AF,TSPEAR
503640,21:45948631:G>A,NM_144991.2:c.791-165C>T,\N,\N,5/11,Unknown significance,\N,intron_variant,4.96,\N,\N,TSPEAR
503641,21:45948653:C>T,NM_144991.2:c.791-187G>A,\N,\N,5/11,Unknown significance,\N,intron_variant,0.078,0.001,1KG_EAS_AF,TSPEAR
503642,21:45948654:G>A,NM_144991.2:c.791-188C>T,\N,\N,5/11,Unknown significance,\N,intron_variant,2.703,0.0014,1KG_AMR_AF,TSPEAR
503643,21:45948667:A>T,NM_144991.2:c.791-201T>A,\N,\N,5/11,Unknown significance,\N,intron_variant,0.233,0.0008,1KG_AFR_AF,TSPEAR
503644,21:45948674:T>G,NM_144991.2:c.791-208A>C,\N,\N,5/11,Unknown significance,\N,intron_variant,0.732,0.001,1KG_EUR_AF,TSPEAR
503645,21:45948677:C>T,NM_144991.2:c.791-211G>A,\N,\N,5/11,Unknown significance,\N,intron_variant,3.814,0.0008,1KG_AFR_AF,TSPEAR
503646,21:45948695:A>T,NM_144991.2:c.791-229T>A,\N,\N,5/11,Unknown significance,\N,intron_variant,8.799,\N,\N,TSPEAR
503647,21:45948698:C>A,NM_144991.2:c.791-232G>T,\N,\N,5/11,Unknown significance,\N,intron_variant,8.049,\N,\N,TSPEAR
503648,21:45948702:G>A,NM_144991.2:c.791-236C>T,\N,\N,5/11,Unknown significance,\N,intron_variant,6.227,0.0008,1KG_AFR_AF,TSPEAR
503649,21:45948717:C>T,NM_144991.2:c.791-251G>A,\N,\N,5/11,Benign,\N,intron_variant,5.867,0.0144,1KG_AFR_AF,TSPEAR
503650,21:45948718:G>A,NM_144991.2:c.791-252C>T,\N,\N,5/11,Unknown significance,\N,intron_variant,0.882,0.0008,1KG_AFR_AF,TSPEAR
503651,21:45948739:G>T,NM_144991.2:c.791-273C>A,\N,\N,5/11,Unknown significance,\N,intron_variant,1.032,\N,\N,TSPEAR
503652,21:45948760:G>A,NM_144991.2:c.791-294C>T,\N,\N,5/11,Unknown significance,\N,intron_variant,5.996,0.001,1KG_EAS_AF,TSPEAR
503653,21:45948773:G>A,NM_144991.2:c.791-307C>T,\N,\N,5/11,Unknown significance,\N,intron_variant,6.694,\N,\N,TSPEAR
503654,21:45948791:C>G,NM_144991.2:c.791-325G>C,\N,\N,5/11,Unknown significance,\N,intron_variant,3.037,0.0023,1KG_AFR_AF,TSPEAR
503655,21:45948791:C>T,NM_144991.2:c.791-325G>A,\N,\N,5/11,Unknown significance,\N,intron_variant,4.842,\N,\N,TSPEAR
503656,21:45948793:C>T,NM_144991.2:c.791-327G>A,\N,\N,5/11,Unknown significance,\N,intron_variant,4.075,\N,\N,TSPEAR
503657,21:45948799:AGGAG>A,NM_144991.2:c.791-337_791-334del,\N,\N,5/11,Benign,\N,intron_variant,1.372,0.0098,1KG_AFR_AF,TSPEAR
503658,21:45948805:G>C,NM_144991.2:c.791-339C>G,\N,\N,5/11,Unknown significance,\N,intron_variant,0.077,\N,\N,TSPEAR
503659,21:45948819:A>G,NM_144991.2:c.791-353T>C,\N,\N,5/11,Unknown significance,\N,intron_variant,1.141,0.0015,1KG_AFR_AF,TSPEAR
503660,21:45948820:G>C,NM_144991.2:c.791-354C>G,\N,\N,5/11,Benign,\N,intron_variant,0.627,0.4009,1KG_AFR_AF,TSPEAR
503661,21:45948829:C>A,NM_144991.2:c.791-363G>T,\N,\N,5/11,Benign,\N,intron_variant,4.447,0.0099,1KG_EAS_AF,TSPEAR
503662,21:45948835:G>A,NM_144991.2:c.791-369C>T,\N,\N,5/11,Unknown significance,\N,intron_variant,0.861,0.0014,1KG_AMR_AF,TSPEAR
503663,21:45948837:C>T,NM_144991.2:c.791-371G>A,\N,\N,5/11,Unknown significance,\N,intron_variant,3.493,0.0008,1KG_AFR_AF,TSPEAR
503664,21:45948841:T>G,NM_144991.2:c.791-375A>C,\N,\N,5/11,Unknown significance,\N,intron_variant,2.656,\N,\N,TSPEAR
503665,21:45948842:T>C,NM_144991.2:c.791-376A>G,\N,\N,5/11,Unknown significance,\N,intron_variant,2.019,\N,\N,TSPEAR
503666,21:45948854:G>C,NM_144991.2:c.791-388C>G,\N,\N,5/11,Unknown significance,\N,intron_variant,0.963,\N,\N,TSPEAR
503667,21:45948858:C>CGGGG,NM_144991.2:c.791-393_791-392insCCCC,\N,\N,5/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503668,21:45948936:A>G,NM_144991.2:c.791-470T>C,\N,\N,5/11,Unknown significance,\N,intron_variant,0.507,0.0008,1KG_AFR_AF,TSPEAR
503669,21:45948953:C>T,NM_144991.2:c.791-487G>A,\N,\N,5/11,Unknown significance,\N,intron_variant,4.245,\N,\N,TSPEAR
503670,21:45948954:C>T,NM_144991.2:c.791-488G>A,\N,\N,5/11,Unknown significance,\N,intron_variant,1.526,0.0015,1KG_AFR_AF,TSPEAR
503671,21:45948955:G>A,NM_144991.2:c.791-489C>T,\N,\N,5/11,Unknown significance,\N,intron_variant,0.576,\N,\N,TSPEAR
503672,21:45948956:G>A,NM_144991.2:c.791-490C>T,\N,\N,5/11,Benign,\N,intron_variant,2.079,0.0051,1KG_SAS_AF,TSPEAR
503673,21:45948977:C>T,NM_144991.2:c.791-511G>A,\N,\N,5/11,Unknown significance,\N,intron_variant,3.98,\N,\N,TSPEAR
503674,21:45948989:C>T,NM_144991.2:c.791-523G>A,\N,\N,5/11,Unknown significance,\N,intron_variant,0.624,\N,\N,TSPEAR
503675,21:45948999:G>A,NM_144991.2:c.791-533C>T,\N,\N,5/11,Benign,\N,intron_variant,1.66,0.1172,1KG_AFR_AF,TSPEAR
503676,21:45949004:G>A,NM_144991.2:c.791-538C>T,\N,\N,5/11,Unknown significance,\N,intron_variant,1.422,0.0008,1KG_AFR_AF,TSPEAR
503677,21:45949020:C>CACA,NM_144991.2:c.791-555_791-554insTGT,\N,\N,5/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503678,21:45949032:C>T,NM_144991.2:c.791-566G>A,\N,\N,5/11,Unknown significance,\N,intron_variant,1.654,0.001,1KG_EAS_AF,TSPEAR
503679,21:45949036:A>C,NM_144991.2:c.791-570T>G,\N,\N,5/11,Unknown significance,\N,intron_variant,0.057,\N,\N,TSPEAR
503680,21:45949039:C>T,NM_144991.2:c.791-573G>A,\N,\N,5/11,Unknown significance,\N,intron_variant,1.886,0.001,1KG_SAS_AF,TSPEAR
503681,21:45949040:C>G,NM_144991.2:c.791-574G>C,\N,\N,5/11,Unknown significance,\N,intron_variant,0.579,0.004,1KG_EUR_AF,TSPEAR
503682,21:45949057:G>A,NM_144991.2:c.791-591C>T,\N,\N,5/11,Unknown significance,\N,intron_variant,1.722,\N,\N,TSPEAR
503683,21:45949066:C>G,NM_144991.2:c.791-600G>C,\N,\N,5/11,Benign,\N,intron_variant,5.055,0.0328,1KG_EUR_AF,TSPEAR
503684,21:45949073:A>C,NM_144991.2:c.791-607T>G,\N,\N,5/11,Unknown significance,\N,intron_variant,0.002,0.001,1KG_EUR_AF,TSPEAR
503685,21:45949097:C>A,NM_144991.2:c.790+584G>T,\N,\N,5/11,Benign,\N,intron_variant,5.905,0.1672,1KG_AFR_AF,TSPEAR
503686,21:45949109:G>A,NM_144991.2:c.790+572C>T,\N,\N,5/11,Benign,\N,intron_variant,2.659,0.177,1KG_AFR_AF,TSPEAR
503687,21:45949112:G>A,NM_144991.2:c.790+569C>T,\N,\N,5/11,Benign,\N,intron_variant,0.198,0.0112,1KG_SAS_AF,TSPEAR
503688,21:45949122:A>G,NM_144991.2:c.790+559T>C,\N,\N,5/11,Benign,\N,intron_variant,5.705,0.0204,1KG_AFR_AF,TSPEAR
503689,21:45949133:T>C,NM_144991.2:c.790+548A>G,\N,\N,5/11,Unknown significance,\N,intron_variant,2.396,0.001,1KG_EAS_AF,TSPEAR
503690,21:45949139:G>T,NM_144991.2:c.790+542C>A,\N,\N,5/11,Unknown significance,\N,intron_variant,0.552,\N,\N,TSPEAR
503691,21:45949140:C>T,NM_144991.2:c.790+541G>A,\N,\N,5/11,Unknown significance,\N,intron_variant,2.224,\N,\N,TSPEAR
503692,21:45949179:T>A,NM_144991.2:c.790+502A>T,\N,\N,5/11,Unknown significance,\N,intron_variant,5.19,\N,\N,TSPEAR
503693,21:45949199:G>A,NM_144991.2:c.790+482C>T,\N,\N,5/11,Unknown significance,\N,intron_variant,1.592,\N,\N,TSPEAR
503694,21:45949200:C>T,NM_144991.2:c.790+481G>A,\N,\N,5/11,Unknown significance,\N,intron_variant,0.055,0.001,1KG_SAS_AF,TSPEAR
503695,21:45949216:G>C,NM_144991.2:c.790+465C>G,\N,\N,5/11,Benign,\N,intron_variant,1.416,0.0681,1KG_AFR_AF,TSPEAR
503696,21:45949218:C>T,NM_144991.2:c.790+463G>A,\N,\N,5/11,Unknown significance,\N,intron_variant,0.745,\N,\N,TSPEAR
503697,21:45949226:C>T,NM_144991.2:c.790+455G>A,\N,\N,5/11,Benign,\N,intron_variant,1.861,0.1717,1KG_AFR_AF,TSPEAR
503698,21:45949235:C>T,NM_144991.2:c.790+446G>A,\N,\N,5/11,Unknown significance,\N,intron_variant,2.02,0.001,1KG_SAS_AF,TSPEAR
503699,21:45949236:G>A,NM_144991.2:c.790+445C>T,\N,\N,5/11,Unknown significance,\N,intron_variant,1.513,\N,\N,TSPEAR
503700,21:45949257:GC>G,NM_144991.2:c.790+423del,\N,\N,5/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503701,21:45949299:G>A,NM_144991.2:c.790+382C>T,\N,\N,5/11,Unknown significance,\N,intron_variant,4.517,0.001,1KG_SAS_AF,TSPEAR
503702,21:45949301:G>A,NM_144991.2:c.790+380C>T,\N,\N,5/11,Unknown significance,\N,intron_variant,3.924,0.001,1KG_EAS_AF,TSPEAR
503703,21:45949315:T>C,NM_144991.2:c.790+366A>G,\N,\N,5/11,Unknown significance,\N,intron_variant,1.171,\N,\N,TSPEAR
503704,21:45949333:T>TG,NM_144991.2:c.790+347dup,\N,\N,5/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503705,21:45949335:G>C,NM_144991.2:c.790+346C>G,\N,\N,5/11,Unknown significance,\N,intron_variant,1.619,\N,\N,TSPEAR
503706,21:45949348:G>C,NM_144991.2:c.790+333C>G,\N,\N,5/11,Unknown significance,\N,intron_variant,1.734,0.001,1KG_EAS_AF,TSPEAR
503707,21:45949353:G>C,NM_144991.2:c.790+328C>G,\N,\N,5/11,Unknown significance,\N,intron_variant,0.245,0.0041,1KG_SAS_AF,TSPEAR
503708,21:45949441:C>T,NM_144991.2:c.790+240G>A,\N,\N,5/11,Unknown significance,\N,intron_variant,2.573,0.001,1KG_EAS_AF,TSPEAR
503709,21:45949442:G>A,NM_144991.2:c.790+239C>T,\N,\N,5/11,Unknown significance,\N,intron_variant,0.032,0.001,1KG_EUR_AF,TSPEAR
503710,21:45949496:C>T,NM_144991.2:c.790+185G>A,\N,\N,5/11,Unknown significance,\N,intron_variant,7.334,\N,\N,TSPEAR
503711,21:45949499:G>A,NM_144991.2:c.790+182C>T,\N,\N,5/11,Unknown significance,\N,intron_variant,3.047,0.001,1KG_SAS_AF,TSPEAR
503712,21:45949518:C>A,NM_144991.2:c.790+163G>T,\N,\N,5/11,Unknown significance,\N,intron_variant,4.926,0.0008,1KG_AFR_AF,TSPEAR
503713,21:45949539:A>G,NM_144991.2:c.790+142T>C,\N,\N,5/11,Benign,\N,intron_variant,2.453,0.3926,1KG_AFR_AF,TSPEAR
503714,21:45949544:C>T,NM_144991.2:c.790+137G>A,\N,\N,5/11,Unknown significance,\N,intron_variant,1.43,\N,\N,TSPEAR
503715,21:45949551:C>G,NM_144991.2:c.790+130G>C,\N,\N,5/11,Unknown significance,\N,intron_variant,2.168,0.0015,1KG_AFR_AF,TSPEAR
503716,21:45949568:G>A,NM_144991.2:c.790+113C>T,\N,\N,5/11,Unknown significance,\N,intron_variant,5.277,\N,\N,TSPEAR
503717,21:45949575:A>AG,NM_144991.2:c.790+105dup,\N,\N,5/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503718,21:45949577:G>T,NM_144991.2:c.790+104C>A,\N,\N,5/11,Unknown significance,\N,intron_variant,0.657,0,1KG_ALL_AF|1KG_AFR_AF|1KG_AMR_AF|1KG_EAS_AF|1KG_EUR_AF|1KG_SAS_AF,TSPEAR
503719,21:45949582:C>T,NM_144991.2:c.790+99G>A,\N,\N,5/11,Unknown significance,\N,intron_variant,0.404,0.002,1KG_SAS_AF,TSPEAR
503720,21:45949583:G>A,NM_144991.2:c.790+98C>T,\N,\N,5/11,Unknown significance,\N,intron_variant,3.016,\N,\N,TSPEAR
503721,21:45949592:T>C,NM_144991.2:c.790+89A>G,\N,\N,5/11,Unknown significance,\N,intron_variant,3.198,0.0008,1KG_AFR_AF,TSPEAR
503722,21:45949605:C>T,NM_144991.2:c.790+76G>A,\N,\N,5/11,Unknown significance,\N,intron_variant,3.7,\N,\N,TSPEAR
503723,21:45949618:T>C,NM_144991.2:c.790+63A>G,\N,\N,5/11,Unknown significance,\N,intron_variant,1.154,0.001,1KG_EUR_AF,TSPEAR
503724,21:45949620:G>A,NM_144991.2:c.790+61C>T,\N,\N,5/11,Benign,\N,intron_variant,1.274,0.0083,1KG_AFR_AF,TSPEAR
503725,21:45949632:G>A,NM_144991.2:c.790+49C>T,\N,\N,5/11,Unknown significance,\N,intron_variant,5.071,0.0000456607,EXAC_NFE_AF,TSPEAR
503726,21:45949634:C>A,NM_144991.2:c.790+47G>T,\N,\N,5/11,Unknown significance,\N,intron_variant,6.223,0.0000620578,EXAC_SAS_AF,TSPEAR
503727,21:45949635:T>C,NM_144991.2:c.790+46A>G,\N,\N,5/11,Unknown significance,\N,intron_variant,0.694,0.0000618888,EXAC_SAS_AF,TSPEAR
503728,21:45949637:TCG>T,NM_144991.2:c.790+42_790+43del,\N,\N,5/11,Unknown significance,\N,intron_variant,4.436,0.000123701,EXAC_SAS_AF,TSPEAR
503729,21:45949638:C>T,NM_144991.2:c.790+43G>A,\N,\N,5/11,Unknown significance,\N,intron_variant,5.451,0.0000867303,EXAC_AMR_AF,TSPEAR
503730,21:45949639:G>A,NM_144991.2:c.790+42C>T,\N,\N,5/11,Unknown significance,\N,intron_variant,3.8,0.00019802,EXAC_AFR_AF,TSPEAR
503731,21:45949641:A>G,NM_144991.2:c.790+40T>C,\N,\N,5/11,Benign,\N,intron_variant,4.667,0.3298,1KG_AFR_AF,TSPEAR
503732,21:45949652:G>T,NM_144991.2:c.790+29C>A,\N,\N,5/11,Unknown significance,\N,intron_variant,3.573,0.0000152031,EXAC_NFE_AF,TSPEAR
503733,21:45949661:C>T,NM_144991.2:c.790+20G>A,\N,\N,5/11,Unknown significance,\N,intron_variant,2.443,0.0015,1KG_AFR_AF,TSPEAR
503734,21:45949662:G>A,NM_144991.2:c.790+19C>T,\N,\N,5/11,Unknown significance,\N,intron_variant,0.287,0.0008,1KG_AFR_AF,TSPEAR
503735,21:45949663:G>C,NM_144991.2:c.790+18C>G,\N,\N,5/11,Unknown significance,\N,intron_variant,1.308,\N,\N,TSPEAR
503736,21:45949667:GC>G,NM_144991.2:c.790+13del,\N,\N,5/11,Unknown significance,\N,intron_variant,2.964,0.0000865651,EXAC_AMR_AF,TSPEAR
503737,21:45949668:C>T,NM_144991.2:c.790+13G>A,\N,\N,5/11,Unknown significance,\N,intron_variant,4.206,0.000097924,EXAC_AFR_AF,TSPEAR
503738,21:45949669:C>A,NM_144991.2:c.790+12G>T,\N,\N,5/11,Unknown significance,\N,intron_variant,6.944,0.0000865651,EXAC_AMR_AF,TSPEAR
503739,21:45949676:CTAACCATAGG>C,NM_144991.2:c.785_790+4del,\N,5/12,5/11,Unknown significance,\N,splice_donor_variant&coding_sequence_variant&intron_variant,30,\N,\N,TSPEAR
503740,21:45949677:T>C,NM_144991.2:c.790+4A>G,\N,\N,5/11,Unknown significance,\N,splice_region_variant&intron_variant,11.18,\N,\N,TSPEAR
503741,21:45949683:T>C,NM_144991.2:c.788A>G,NP_659428.2:p.Tyr263Cys,5/12,\N,Unknown significance,\N,missense_variant&splice_region_variant,23,0.0000151313,EXAC_NFE_AF,TSPEAR
503742,21:45949687:G>A,NM_144991.2:c.784C>T,NP_659428.2:p.Pro262Ser,5/12,\N,Unknown significance,\N,missense_variant,13.06,0.0000302471,EXAC_NFE_AF,TSPEAR
503743,21:45949689:T>C,NM_144991.2:c.782A>G,NP_659428.2:p.Tyr261Cys,5/12,\N,Unknown significance,\N,missense_variant,22.7,0.00029098,EXAC_AFR_AF,TSPEAR
503744,21:45949696:G>A,NM_144991.2:c.775C>T,NP_659428.2:p.Leu259=,5/12,\N,Unknown significance,\N,synonymous_variant,9.127,0.0000151162,EXAC_NFE_AF,TSPEAR
503745,21:45949703:G>A,NM_144991.2:c.768C>T,NP_659428.2:p.Asn256=,5/12,\N,Unknown significance,\N,synonymous_variant,11.27,0.000116279,EVS_EA_AF,TSPEAR
503746,21:45949721:C>T,NM_144991.2:c.750G>A,NP_659428.2:p.Thr250=,5/12,\N,Unknown significance,\N,synonymous_variant,18.32,0.000151423,EXAC_FIN_AF,TSPEAR
503747,21:45949721:CG>C,NM_144991.2:c.749del,NP_659428.2:p.Thr250ArgfsTer10,5/12,\N,Unknown significance,\N,frameshift_variant,30,0.0000151213,EXAC_NFE_AF,TSPEAR
503748,21:45949740:C>T,NM_144991.2:c.731G>A,NP_659428.2:p.Arg244Gln,5/12,\N,Likely benign,\N,missense_variant,14.46,0.00248364,EXAC_SAS_AF,TSPEAR
503749,21:45949741:G>A,NM_144991.2:c.730C>T,NP_659428.2:p.Arg244Trp,5/12,\N,Unknown significance,\N,missense_variant,26.8,0.000453926,EVS_AA_AF,TSPEAR
503750,21:45949741:G>C,NM_144991.2:c.730C>G,NP_659428.2:p.Arg244Gly,5/12,\N,Likely benign,\N,missense_variant,14.5,0.00023175,EXAC_EAS_AF,TSPEAR
503751,21:45949741:G>T,NM_144991.2:c.730C>A,NP_659428.2:p.Arg244=,5/12,\N,Unknown significance,\N,synonymous_variant,12.75,0.0000605767,EXAC_SAS_AF,TSPEAR
503752,21:45949743:G>A,NM_144991.2:c.728C>T,NP_659428.2:p.Pro243Leu,5/12,\N,Unknown significance,\N,missense_variant,24.2,0.0000971062,EXAC_AFR_AF,TSPEAR
503753,21:45949744:G>A,NM_144991.2:c.727C>T,NP_659428.2:p.Pro243Ser,5/12,\N,Unknown significance,\N,missense_variant,27.6,\N,\N,TSPEAR
503754,21:45949748:G>A,NM_144991.2:c.723C>T,NP_659428.2:p.Ser241=,5/12,\N,Unknown significance,\N,synonymous_variant,12.08,0.0008,1KG_AFR_AF,TSPEAR
503755,21:45949753:G>T,NM_144991.2:c.718C>A,NP_659428.2:p.Leu240Met,5/12,\N,Unknown significance,\N,missense_variant,23.6,0.000153092,EXAC_FIN_AF,TSPEAR
503756,21:45949756:C>A,NM_144991.2:c.715G>T,NP_659428.2:p.Val239Leu,5/12,\N,Likely benign,\N,missense_variant,9.25,0.0000303739,EXAC_NFE_AF,TSPEAR
503757,21:45949757:C>T,NM_144991.2:c.714G>A,NP_659428.2:p.Ala238=,5/12,\N,Unknown significance,\N,synonymous_variant,13.52,0.00209302,EVS_EA_AF,TSPEAR
503758,21:45949758:G>A,NM_144991.2:c.713C>T,NP_659428.2:p.Ala238Val,5/12,\N,Unknown significance,\N,missense_variant,19.27,0.000461681,EXAC_FIN_AF,TSPEAR
503759,21:45949760:C>G,NM_144991.2:c.711G>C,NP_659428.2:p.Leu237=,5/12,\N,Unknown significance,\N,synonymous_variant,7.342,0.00204267,EVS_AA_AF,TSPEAR
503760,21:45949764:G>A,NM_144991.2:c.707C>T,NP_659428.2:p.Pro236Leu,5/12,\N,Likely benign,\N,missense_variant,9.492,0.000061192,EXAC_SAS_AF,TSPEAR
503761,21:45949766:G>A,NM_144991.2:c.705C>T,NP_659428.2:p.Ala235=,5/12,\N,Unknown significance,\N,synonymous_variant,6.204,0.000087184,EXAC_AMR_AF,TSPEAR
503762,21:45949767:G>A,NM_144991.2:c.704C>T,NP_659428.2:p.Ala235Val,5/12,\N,Likely benign,\N,missense_variant,15.35,0.0000152448,EXAC_NFE_AF,TSPEAR
503763,21:45949768:C>T,NM_144991.2:c.703G>A,NP_659428.2:p.Ala235Thr,5/12,\N,Likely benign,\N,missense_variant,11.69,0.000184638,EXAC_SAS_AF,TSPEAR
503764,21:45949769:G>A,NM_144991.2:c.702C>T,NP_659428.2:p.Asn234=,5/12,\N,Benign,\N,synonymous_variant,4.395,0.00819847,EXAC_NFE_AF,TSPEAR
503765,21:45949774:T>C,NM_144991.2:c.697A>G,NP_659428.2:p.Arg233Gly,5/12,\N,Likely benign,\N,missense_variant,9.988,0.0000986777,EXAC_AFR_AF,TSPEAR
503766,21:45949793:G>A,NM_144991.2:c.678C>T,NP_659428.2:p.Thr226=,5/12,\N,Unknown significance,\N,synonymous_variant,4.66,0.000356952,EXAC_AMR_AF,TSPEAR
503767,21:45949798:C>T,NM_144991.2:c.673G>A,NP_659428.2:p.Ala225Thr,5/12,\N,Unknown significance,\N,missense_variant,34,0.000143253,EXAC_NFE_AF,TSPEAR
503768,21:45949799:G>A,NM_144991.2:c.672C>T,NP_659428.2:p.Asp224=,5/12,\N,Unknown significance,\N,synonymous_variant,9.852,0.0008,1KG_AFR_AF,TSPEAR
503769,21:45949799:G>T,NM_144991.2:c.672C>A,NP_659428.2:p.Asp224Glu,5/12,\N,Unknown significance,\N,missense_variant,22.2,0.000103627,EXAC_AFR_AF,TSPEAR
503770,21:45949803:G>A,NM_144991.2:c.668C>T,NP_659428.2:p.Ser223Leu,5/12,\N,Unknown significance,\N,missense_variant,31,0.002,1KG_EUR_AF,TSPEAR
503771,21:45949808:C>T,NM_144991.2:c.663G>A,NP_659428.2:p.Pro221=,5/12,\N,Unknown significance,\N,synonymous_variant,12.98,0.0000927988,EXAC_AMR_AF,TSPEAR
503772,21:45949809:G>A,NM_144991.2:c.662C>T,NP_659428.2:p.Pro221Leu,5/12,\N,Unknown significance,\N,missense_variant,32,0.001,1KG_EAS_AF,TSPEAR
503773,21:45949831:C>A,NM_144991.2:c.640G>T,NP_659428.2:p.Val214Leu,5/12,\N,Likely benign,\N,missense_variant,9.625,0.000036665,EXAC_NFE_AF,TSPEAR
503774,21:45949831:C>T,NM_144991.2:c.640G>A,NP_659428.2:p.Val214Met,5/12,\N,Likely benign,\N,missense_variant,18.19,0.000268432,EXAC_SAS_AF,TSPEAR
503775,21:45949834:G>A,NM_144991.2:c.637C>T,NP_659428.2:p.Leu213=,5/12,\N,Unknown significance,\N,synonymous_variant,9.672,\N,\N,TSPEAR
503776,21:45949836:C>T,NM_144991.2:c.635G>A,NP_659428.2:p.Gly212Glu,5/12,\N,Unknown significance,\N,missense_variant&splice_region_variant,29.8,0.000075884,EXAC_NFE_AF,TSPEAR
503777,21:45949839:T>C,NM_144991.2:c.634-2A>G,\N,\N,4/11,Unknown significance,\N,splice_acceptor_variant,24.6,0.000116333,EVS_EA_AF,TSPEAR
503778,21:45949841:CAG>C,NM_144991.2:c.634-6_634-5del,\N,\N,4/11,Unknown significance,\N,splice_region_variant&intron_variant,13.64,0.000127226,EXAC_AFR_AF,TSPEAR
503779,21:45949844:A>G,NM_144991.2:c.634-7T>C,\N,\N,4/11,Unknown significance,\N,splice_region_variant&intron_variant,11.45,\N,\N,TSPEAR
503780,21:45949845:G>A,NM_144991.2:c.634-8C>T,\N,\N,4/11,Unknown significance,\N,splice_region_variant&intron_variant,10.28,0.0000206971,EXAC_NFE_AF,TSPEAR
503781,21:45949847:G>A,NM_144991.2:c.634-10C>T,\N,\N,4/11,Unknown significance,\N,intron_variant,12.89,\N,\N,TSPEAR
503782,21:45949850:G>A,NM_144991.2:c.634-13C>T,\N,\N,4/11,Unknown significance,\N,intron_variant,12.7,0.000126614,EXAC_AMR_AF,TSPEAR
503783,21:45949852:A>G,NM_144991.2:c.634-15T>C,\N,\N,4/11,Unknown significance,\N,intron_variant,10.09,0.000773994,EXAC_AMR_AF,TSPEAR
503784,21:45949858:C>G,NM_144991.2:c.634-21G>C,\N,\N,4/11,Unknown significance,\N,intron_variant,8.02,0,EXAC_ALL_AF|EXAC_AFR_AF|EXAC_AMR_AF|EXAC_EAS_AF|EXAC_FIN_AF|EXAC_NFE_AF|EXAC_OTH_AF|EXAC_SAS_AF,TSPEAR
503785,21:45949858:C>T,NM_144991.2:c.634-21G>A,\N,\N,4/11,Unknown significance,\N,intron_variant,9.576,0.000116279,EVS_EA_AF,TSPEAR
503786,21:45949862:C>G,NM_144991.2:c.634-25G>C,\N,\N,4/11,Benign,\N,intron_variant,8.402,0.0512528,EXAC_AFR_AF,TSPEAR
503787,21:45949868:C>T,NM_144991.2:c.634-31G>A,\N,\N,4/11,Unknown significance,\N,intron_variant,10.81,0.00238095,EXAC_OTH_AF,TSPEAR
503788,21:45949869:G>A,NM_144991.2:c.634-32C>T,\N,\N,4/11,Benign,\N,intron_variant,8.962,0.0129,1KG_AFR_AF,TSPEAR
503789,21:45949870:C>T,NM_144991.2:c.634-33G>A,\N,\N,4/11,Unknown significance,\N,intron_variant,10.64,0.0000301405,EXAC_NFE_AF,TSPEAR
503790,21:45949871:G>A,NM_144991.2:c.634-34C>T,\N,\N,4/11,Unknown significance,\N,intron_variant,9.053,0.000194175,EXAC_AMR_AF,TSPEAR
503791,21:45949872:C>T,NM_144991.2:c.634-35G>A,\N,\N,4/11,Unknown significance,\N,intron_variant,8.715,0.000124146,EXAC_NFE_AF,TSPEAR
503792,21:45949874:G>C,NM_144991.2:c.634-37C>G,\N,\N,4/11,Unknown significance,\N,intron_variant,4.554,0.001,1KG_SAS_AF,TSPEAR
503793,21:45949879:G>A,NM_144991.2:c.634-42C>T,\N,\N,4/11,Unknown significance,\N,intron_variant,4.988,0.000109067,EXAC_NFE_AF,TSPEAR
503794,21:45949880:G>A,NM_144991.2:c.634-43C>T,\N,\N,4/11,Unknown significance,\N,intron_variant,4.72,0.001,1KG_SAS_AF,TSPEAR
503795,21:45949888:C>T,NM_144991.2:c.634-51G>A,\N,\N,4/11,Unknown significance,\N,intron_variant,2.117,\N,\N,TSPEAR
503796,21:45949889:G>A,NM_144991.2:c.634-52C>T,\N,\N,4/11,Unknown significance,\N,intron_variant,3.692,0.00106458,EXAC_SAS_AF,TSPEAR
503797,21:45949894:G>A,NM_144991.2:c.634-57C>T,\N,\N,4/11,Unknown significance,\N,intron_variant,3.489,0.0014,1KG_AMR_AF,TSPEAR
503798,21:45949899:C>T,NM_144991.2:c.634-62G>A,\N,\N,4/11,Unknown significance,\N,intron_variant,5.405,\N,\N,TSPEAR
503799,21:45949900:G>A,NM_144991.2:c.634-63C>T,\N,\N,4/11,Unknown significance,\N,intron_variant,4.502,\N,\N,TSPEAR
503800,21:45949902:C>T,NM_144991.2:c.634-65G>A,\N,\N,4/11,Benign,\N,intron_variant,3.698,0.0069,1KG_EAS_AF,TSPEAR
503801,21:45949918:A>T,NM_144991.2:c.634-81T>A,\N,\N,4/11,Unknown significance,\N,intron_variant,3.31,0.001,1KG_SAS_AF,TSPEAR
503802,21:45949924:A>G,NM_144991.2:c.634-87T>C,\N,\N,4/11,Unknown significance,\N,intron_variant,0.919,\N,\N,TSPEAR
503803,21:45949928:C>T,NM_144991.2:c.634-91G>A,\N,\N,4/11,Unknown significance,\N,intron_variant,1.422,\N,\N,TSPEAR
503804,21:45949933:G>A,NM_144991.2:c.634-96C>T,\N,\N,4/11,Unknown significance,\N,intron_variant,1.688,0.001,1KG_SAS_AF,TSPEAR
503805,21:45949940:G>A,NM_144991.2:c.634-103C>T,\N,\N,4/11,Unknown significance,\N,intron_variant,1.877,0.0008,1KG_AFR_AF,TSPEAR
503806,21:45949941:G>A,NM_144991.2:c.634-104C>T,\N,\N,4/11,Unknown significance,\N,intron_variant,2.929,\N,\N,TSPEAR
503807,21:45949952:T>A,NM_144991.2:c.634-115A>T,\N,\N,4/11,Unknown significance,\N,intron_variant,6.366,0.001,1KG_EUR_AF,TSPEAR
503808,21:45949957:G>A,NM_144991.2:c.634-120C>T,\N,\N,4/11,Unknown significance,\N,intron_variant,0.532,0.001,1KG_SAS_AF,TSPEAR
503809,21:45949973:C>T,NM_144991.2:c.634-136G>A,\N,\N,4/11,Unknown significance,\N,intron_variant,1.733,0.001,1KG_EUR_AF,TSPEAR
503810,21:45949996:T>G,NM_144991.2:c.634-159A>C,\N,\N,4/11,Unknown significance,\N,intron_variant,4.162,0.0023,1KG_AFR_AF,TSPEAR
503811,21:45949999:T>C,NM_144991.2:c.634-162A>G,\N,\N,4/11,Benign,\N,intron_variant,1.039,0.1679,1KG_AFR_AF,TSPEAR
503812,21:45950030:T>C,NM_144991.2:c.634-193A>G,\N,\N,4/11,Unknown significance,\N,intron_variant,1.853,\N,\N,TSPEAR
503813,21:45950042:G>A,NM_144991.2:c.634-205C>T,\N,\N,4/11,Unknown significance,\N,intron_variant,0.372,0.001,1KG_SAS_AF,TSPEAR
503814,21:45950055:C>A,NM_144991.2:c.634-218G>T,\N,\N,4/11,Unknown significance,\N,intron_variant,6.089,\N,\N,TSPEAR
503815,21:45950061:A>AG,NM_144991.2:c.634-225dup,\N,\N,4/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503816,21:45950065:G>GT,NM_144991.2:c.634-229dup,\N,\N,4/11,Benign,\N,intron_variant,0.096,0.1679,1KG_AFR_AF,TSPEAR
503817,21:45950065:G>GTT,NM_144991.2:c.634-230_634-229dup,\N,\N,4/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503818,21:45950165:A>G,NM_144991.2:c.634-328T>C,\N,\N,4/11,Unknown significance,\N,intron_variant,4.128,0.0045,1KG_AFR_AF,TSPEAR
503819,21:45950224:C>T,NM_144991.2:c.634-387G>A,\N,\N,4/11,Unknown significance,\N,intron_variant,4.999,0.0014,1KG_AMR_AF,TSPEAR
503820,21:45950228:C>T,NM_144991.2:c.634-391G>A,\N,\N,4/11,Unknown significance,\N,intron_variant,7.44,\N,\N,TSPEAR
503821,21:45950232:C>G,NM_144991.2:c.634-395G>C,\N,\N,4/11,Unknown significance,\N,intron_variant,2.338,\N,\N,TSPEAR
503822,21:45950248:CAC>TGTCCATCCATCAGTCCAAT,NM_144991.2:c.634-413_634-411delinsATTGGACTGATGGATGGACA,\N,\N,4/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503823,21:45950307:C>T,NM_144991.2:c.634-470G>A,\N,\N,4/11,Unknown significance,\N,intron_variant,4.723,\N,\N,TSPEAR
503824,21:45950323:C>T,NM_144991.2:c.634-486G>A,\N,\N,4/11,Unknown significance,\N,intron_variant,3.194,\N,\N,TSPEAR
503825,21:45950336:C>T,NM_144991.2:c.634-499G>A,\N,\N,4/11,Benign,\N,intron_variant,0.41,0.0139,1KG_EAS_AF,TSPEAR
503826,21:45950341:C>T,NM_144991.2:c.634-504G>A,\N,\N,4/11,Unknown significance,\N,intron_variant,0.172,0.0045,1KG_AFR_AF,TSPEAR
503827,21:45950342:G>A,NM_144991.2:c.634-505C>T,\N,\N,4/11,Unknown significance,\N,intron_variant,0.626,\N,\N,TSPEAR
503828,21:45950352:C>A,NM_144991.2:c.634-515G>T,\N,\N,4/11,Benign,\N,intron_variant,0.198,0.1672,1KG_AFR_AF,TSPEAR
503829,21:45950398:G>GCATC,NM_144991.2:c.633+524_633+527dup,\N,\N,4/11,Benign,\N,intron_variant,0.537,0.0091,1KG_AFR_AF,TSPEAR
503830,21:45950398:GCATCCATCCATC>G,NM_144991.2:c.633+516_633+527del,\N,\N,4/11,Unknown significance,\N,intron_variant,5.534,\N,\N,TSPEAR
503831,21:45950447:CATCT>C,NM_144991.2:c.633+475_633+478del,\N,\N,4/11,Unknown significance,\N,intron_variant,9.482,0.0015,1KG_AFR_AF,TSPEAR
503832,21:45950458:C>T,NM_144991.2:c.633+468G>A,\N,\N,4/11,Unknown significance,\N,intron_variant,1.195,0.0015,1KG_AFR_AF,TSPEAR
503833,21:45950494:G>A,NM_144991.2:c.633+432C>T,\N,\N,4/11,Unknown significance,\N,intron_variant,3.125,0.001,1KG_EUR_AF,TSPEAR
503834,21:45950511:A>G,NM_144991.2:c.633+415T>C,\N,\N,4/11,Unknown significance,\N,intron_variant,0.076,\N,\N,TSPEAR
503835,21:45950540:C>T,NM_144991.2:c.633+386G>A,\N,\N,4/11,Benign,\N,intron_variant,3.048,0.0209,1KG_EUR_AF,TSPEAR
503836,21:45950550:G>A,NM_144991.2:c.633+376C>T,\N,\N,4/11,Benign,\N,intron_variant,0.265,0.2791,1KG_AFR_AF,TSPEAR
503837,21:45950553:G>A,NM_144991.2:c.633+373C>T,\N,\N,4/11,Unknown significance,\N,intron_variant,1.597,\N,\N,TSPEAR
503838,21:45950565:C>T,NM_144991.2:c.633+361G>A,\N,\N,4/11,Unknown significance,\N,intron_variant,2.835,\N,\N,TSPEAR
503839,21:45950569:C>T,NM_144991.2:c.633+357G>A,\N,\N,4/11,Unknown significance,\N,intron_variant,1.846,\N,\N,TSPEAR
503840,21:45950602:C>T,NM_144991.2:c.633+324G>A,\N,\N,4/11,Benign,\N,intron_variant,4.672,0.0197,1KG_AFR_AF,TSPEAR
503841,21:45950602:CC>TG,NM_144991.2:c.633+323_633+324delinsCA,\N,\N,4/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503842,21:45950603:C>G,NM_144991.2:c.633+323G>C,\N,\N,4/11,Benign,\N,intron_variant,0.345,0.4039,1KG_AFR_AF,TSPEAR
503843,21:45950612:C>G,NM_144991.2:c.633+314G>C,\N,\N,4/11,Unknown significance,\N,intron_variant,2.837,0.0008,1KG_AFR_AF,TSPEAR
503844,21:45950649:G>A,NM_144991.2:c.633+277C>T,\N,\N,4/11,Unknown significance,\N,intron_variant,0.052,0.0008,1KG_AFR_AF,TSPEAR
503845,21:45950656:G>A,NM_144991.2:c.633+270C>T,\N,\N,4/11,Unknown significance,\N,intron_variant,4.954,\N,\N,TSPEAR
503846,21:45950671:G>A,NM_144991.2:c.633+255C>T,\N,\N,4/11,Unknown significance,\N,intron_variant,0.736,\N,\N,TSPEAR
503847,21:45950685:T>G,NM_144991.2:c.633+241A>C,\N,\N,4/11,Unknown significance,\N,intron_variant,5.201,0.001,1KG_EAS_AF,TSPEAR
503848,21:45950722:C>T,NM_144991.2:c.633+204G>A,\N,\N,4/11,Unknown significance,\N,intron_variant,3.86,\N,\N,TSPEAR
503849,21:45950736:C>T,NM_144991.2:c.633+190G>A,\N,\N,4/11,Unknown significance,\N,intron_variant,1.783,0.0014,1KG_AMR_AF,TSPEAR
503850,21:45950755:A>G,NM_144991.2:c.633+171T>C,\N,\N,4/11,Unknown significance,\N,intron_variant,4.477,\N,\N,TSPEAR
503851,21:45950763:A>G,NM_144991.2:c.633+163T>C,\N,\N,4/11,Benign,\N,intron_variant,5.728,0.1467,1KG_AFR_AF,TSPEAR
503852,21:45950770:G>A,NM_144991.2:c.633+156C>T,\N,\N,4/11,Benign,\N,intron_variant,4.426,0.0072,1KG_SAS_AF,TSPEAR
503853,21:45950771:C>T,NM_144991.2:c.633+155G>A,\N,\N,4/11,Unknown significance,\N,intron_variant,2.852,0.001,1KG_EUR_AF,TSPEAR
503854,21:45950772:G>A,NM_144991.2:c.633+154C>T,\N,\N,4/11,Unknown significance,\N,intron_variant,1.781,0.003,1KG_AFR_AF,TSPEAR
503855,21:45950786:G>A,NM_144991.2:c.633+140C>T,\N,\N,4/11,Benign,\N,intron_variant,3.597,0.1755,1KG_AFR_AF,TSPEAR
503856,21:45950799:G>A,NM_144991.2:c.633+127C>T,\N,\N,4/11,Benign,\N,intron_variant,0.272,0.0695,1KG_SAS_AF,TSPEAR
503857,21:45950802:C>T,NM_144991.2:c.633+124G>A,\N,\N,4/11,Benign,\N,intron_variant,0.165,0.1755,1KG_AFR_AF,TSPEAR
503858,21:45950803:G>A,NM_144991.2:c.633+123C>T,\N,\N,4/11,Unknown significance,\N,intron_variant,0.908,\N,\N,TSPEAR
503859,21:45950808:A>G,NM_144991.2:c.633+118T>C,\N,\N,4/11,Benign,\N,intron_variant,1.956,0.3949,1KG_AFR_AF,TSPEAR
503860,21:45950852:G>A,NM_144991.2:c.633+74C>T,\N,\N,4/11,Unknown significance,\N,intron_variant,4.496,0.002,1KG_EUR_AF,TSPEAR
503861,21:45950878:T>C,NM_144991.2:c.633+48A>G,\N,\N,4/11,Unknown significance,\N,intron_variant,2.454,\N,\N,TSPEAR
503862,21:45950886:C>T,NM_144991.2:c.633+40G>A,\N,\N,4/11,Unknown significance,\N,intron_variant,2.086,0.0000166262,EXAC_NFE_AF,TSPEAR
503863,21:45950887:G>A,NM_144991.2:c.633+39C>T,\N,\N,4/11,Unknown significance,\N,intron_variant,0.059,0.000469395,EXAC_AMR_AF,TSPEAR
503864,21:45950893:C>T,NM_144991.2:c.633+33G>A,\N,\N,4/11,Unknown significance,\N,intron_variant,2.216,0.000178444,EXAC_FIN_AF,TSPEAR
503865,21:45950894:G>A,NM_144991.2:c.633+32C>T,\N,\N,4/11,Unknown significance,\N,intron_variant,0.628,0.000131234,EXAC_SAS_AF,TSPEAR
503866,21:45950896:G>T,NM_144991.2:c.633+30C>A,\N,\N,4/11,Unknown significance,\N,intron_variant,1.972,0.0000163591,EXAC_NFE_AF,TSPEAR
503867,21:45950914:C>T,NM_144991.2:c.633+12G>A,\N,\N,4/11,Unknown significance,\N,intron_variant,4.959,0.0000157823,EXAC_NFE_AF,TSPEAR
503868,21:45950919:T>C,NM_144991.2:c.633+7A>G,\N,\N,4/11,Unknown significance,\N,splice_region_variant&intron_variant,0.33,0.000357079,EXAC_AMR_AF,TSPEAR
503869,21:45950923:C>T,NM_144991.2:c.633+3G>A,\N,\N,4/11,Unknown significance,\N,splice_region_variant&intron_variant,6.324,0.0000635324,EXAC_SAS_AF,TSPEAR
503870,21:45950924:G>A,NM_144991.2:c.633+2C>T,\N,\N,4/11,Unknown significance,\N,splice_donor_variant,13.43,0.000348837,EVS_EA_AF,TSPEAR
503871,21:45950928:T>A,NM_144991.2:c.631A>T,NP_659428.2:p.Met211Leu,4/12,\N,Unknown significance,\N,missense_variant&splice_region_variant,19.68,0.0008,1KG_AFR_AF,TSPEAR
503872,21:45950928:T>C,NM_144991.2:c.631A>G,NP_659428.2:p.Met211Val,4/12,\N,Unknown significance,\N,missense_variant&splice_region_variant,12.18,0.000226963,EVS_AA_AF,TSPEAR
503873,21:45950936:C>A,NM_144991.2:c.623G>T,NP_659428.2:p.Gly208Val,4/12,\N,Unknown significance,\N,missense_variant,25.7,0.0000625704,EXAC_SAS_AF,TSPEAR
503874,21:45950936:C>G,NM_144991.2:c.623G>C,NP_659428.2:p.Gly208Ala,4/12,\N,Unknown significance,\N,missense_variant,24.1,0.0000881523,EXAC_AMR_AF,TSPEAR
503875,21:45950939:T>C,NM_144991.2:c.620A>G,NP_659428.2:p.Lys207Arg,4/12,\N,Unknown significance,\N,missense_variant,10.47,0.000312266,EXAC_SAS_AF,TSPEAR
503876,21:45950944:TCTC>T,NM_144991.2:c.612_614del,NP_659428.2:p.Arg205del,4/12,\N,Unknown significance,\N,inframe_deletion,13.44,0.0000877655,EXAC_AMR_AF,TSPEAR
503877,21:45950948:C>A,NM_144991.2:c.611G>T,NP_659428.2:p.Arg204Met,4/12,\N,Unknown significance,\N,missense_variant,24.4,0.00068089,EVS_AA_AF,TSPEAR
503878,21:45950951:C>T,NM_144991.2:c.608G>A,NP_659428.2:p.Arg203Gln,4/12,\N,Unknown significance,\N,missense_variant,28.9,0.000087581,EXAC_AMR_AF,TSPEAR
503879,21:45950952:G>A,NM_144991.2:c.607C>T,NP_659428.2:p.Arg203Trp,4/12,\N,Unknown significance,\N,missense_variant,25.6,0.0041,1KG_SAS_AF,TSPEAR
503880,21:45950952:G>C,NM_144991.2:c.607C>G,NP_659428.2:p.Arg203Gly,4/12,\N,Unknown significance,\N,missense_variant,24,0.0000152924,EXAC_NFE_AF,TSPEAR
503881,21:45950954:C>T,NM_144991.2:c.605G>A,NP_659428.2:p.Ser202Asn,4/12,\N,Likely benign,\N,missense_variant,12.16,0.000226963,EVS_AA_AF,TSPEAR
503882,21:45950958:C>A,NM_144991.2:c.601G>T,NP_659428.2:p.Gly201Cys,4/12,\N,Unknown significance,\N,missense_variant,28,0.000123808,EXAC_SAS_AF,TSPEAR
503883,21:45950958:C>T,NM_144991.2:c.601G>A,NP_659428.2:p.Gly201Ser,4/12,\N,Unknown significance,\N,missense_variant,27.7,0.00115207,EXAC_OTH_AF,TSPEAR
503884,21:45950959:G>A,NM_144991.2:c.600C>T,NP_659428.2:p.Val200=,4/12,\N,Unknown significance,\N,synonymous_variant,5.689,0.0000618812,EXAC_SAS_AF,TSPEAR
503885,21:45950961:C>A,NM_144991.2:c.598G>T,NP_659428.2:p.Val200Phe,4/12,\N,Likely benign,\N,missense_variant,20.5,0.0000152653,EXAC_NFE_AF,TSPEAR
503886,21:45950961:C>T,NM_144991.2:c.598G>A,NP_659428.2:p.Val200Ile,4/12,\N,Likely benign,\N,missense_variant,0.119,0.0000618582,EXAC_SAS_AF,TSPEAR
503887,21:45950962:G>A,NM_144991.2:c.597C>T,NP_659428.2:p.Phe199=,4/12,\N,Unknown significance,\N,synonymous_variant,8.403,0.000232558,EVS_EA_AF,TSPEAR
503888,21:45950964:A>C,NM_144991.2:c.595T>G,NP_659428.2:p.Phe199Val,4/12,\N,Unknown significance,\N,missense_variant,21.5,0.000481696,EXAC_FIN_AF,TSPEAR
503889,21:45950965:G>A,NM_144991.2:c.594C>T,NP_659428.2:p.Phe198=,4/12,\N,Unknown significance,\N,synonymous_variant,6.42,0.00206652,EXAC_AFR_AF,TSPEAR
503890,21:45950965:G>C,NM_144991.2:c.594C>G,NP_659428.2:p.Phe198Leu,4/12,\N,Unknown significance,\N,missense_variant,15.2,0.0000305241,EXAC_NFE_AF,TSPEAR
503891,21:45950969:C>T,NM_144991.2:c.590G>A,NP_659428.2:p.Arg197Gln,4/12,\N,Likely benign,\N,missense_variant,23.2,0.0000457708,EXAC_NFE_AF,TSPEAR
503892,21:45950970:G>A,NM_144991.2:c.589C>T,NP_659428.2:p.Arg197Ter,4/12,\N,Unknown significance,\N,stop_gained,36,0.000579728,EXAC_NFE_AF,TSPEAR
503893,21:45950971:A>C,NM_144991.2:c.588T>G,NP_659428.2:p.Ala196=,4/12,\N,Unknown significance,\N,synonymous_variant,0.036,0.0000152569,EXAC_NFE_AF,TSPEAR
503894,21:45950972:G>A,NM_144991.2:c.587C>T,NP_659428.2:p.Ala196Val,4/12,\N,Unknown significance,\N,missense_variant,24.8,0.0000872753,EXAC_AMR_AF,TSPEAR
503895,21:45950975:C>G,NM_144991.2:c.584G>C,NP_659428.2:p.Gly195Ala,4/12,\N,Unknown significance,\N,missense_variant,20.3,0.000015262,EXAC_NFE_AF,TSPEAR
503896,21:45950975:C>T,NM_144991.2:c.584G>A,NP_659428.2:p.Gly195Glu,4/12,\N,Unknown significance,\N,missense_variant,25.4,0.000015262,EXAC_NFE_AF,TSPEAR
503897,21:45950976:C>T,NM_144991.2:c.583G>A,NP_659428.2:p.Gly195Arg,4/12,\N,Unknown significance,\N,missense_variant,23.9,0.0000763266,EXAC_NFE_AF,TSPEAR
503898,21:45950977:T>C,NM_144991.2:c.582A>G,NP_659428.2:p.Lys194=,4/12,\N,Unknown significance,\N,synonymous_variant,0.013,0.0000152662,EXAC_NFE_AF,TSPEAR
503899,21:45950987:A>G,NM_144991.2:c.572T>C,NP_659428.2:p.Leu191Pro,4/12,\N,Unknown significance,\N,missense_variant,23,0.0000621736,EXAC_SAS_AF,TSPEAR
503900,21:45950989:G>C,NM_144991.2:c.570C>G,NP_659428.2:p.Thr190=,4/12,\N,Unknown significance,\N,synonymous_variant,0.045,0.000116279,EVS_EA_AF,TSPEAR
503901,21:45950991:T>C,NM_144991.2:c.568A>G,NP_659428.2:p.Thr190Ala,4/12,\N,Likely benign,\N,missense_variant,0.002,0.0000306448,EXAC_NFE_AF,TSPEAR
503902,21:45950995:T>C,NM_144991.2:c.564A>G,NP_659428.2:p.Pro188=,4/12,\N,Unknown significance,\N,synonymous_variant,0.036,0.0000460094,EXAC_NFE_AF,TSPEAR
503903,21:45950997:G>A,NM_144991.2:c.562C>T,NP_659428.2:p.Pro188Ser,4/12,\N,Unknown significance,\N,missense_variant,23.3,0.001,1KG_SAS_AF,TSPEAR
503904,21:45950998:G>A,NM_144991.2:c.561C>T,NP_659428.2:p.Phe187=,4/12,\N,Unknown significance,\N,synonymous_variant,2.269,\N,\N,TSPEAR
503905,21:45951003:G>A,NM_144991.2:c.556C>T,NP_659428.2:p.Pro186Ser,4/12,\N,Likely benign,\N,missense_variant,7.769,0.000334001,EXAC_FIN_AF,TSPEAR
503906,21:45951007:A>G,NM_144991.2:c.552T>C,NP_659428.2:p.Asp184=,4/12,\N,Benign,\N,synonymous_variant,0.005,0.0393,1KG_AFR_AF,TSPEAR
503907,21:45951009:C>A,NM_144991.2:c.550G>T,NP_659428.2:p.Asp184Tyr,4/12,\N,Unknown significance,\N,missense_variant,25.4,0.000168577,EXAC_FIN_AF,TSPEAR
503908,21:45951009:C>T,NM_144991.2:c.550G>A,NP_659428.2:p.Asp184Asn,4/12,\N,Likely benign,\N,missense_variant,23.4,0.0000637918,EXAC_SAS_AF,TSPEAR
503909,21:45951010:G>A,NM_144991.2:c.549C>T,NP_659428.2:p.Ala183=,4/12,\N,Unknown significance,\N,synonymous_variant,7.33,0.000226963,EVS_AA_AF,TSPEAR
503910,21:45951011:G>A,NM_144991.2:c.548C>T,NP_659428.2:p.Ala183Val,4/12,\N,Likely benign,\N,missense_variant,7.926,0.0000313224,EXAC_NFE_AF,TSPEAR
503911,21:45951028:A>G,NM_144991.2:c.543-12T>C,\N,\N,3/11,Unknown significance,\N,intron_variant,2.064,0.0008,1KG_AFR_AF,TSPEAR
503912,21:45951031:G>A,NM_144991.2:c.543-15C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,4.258,0.000134048,EXAC_SAS_AF,TSPEAR
503913,21:45951035:T>C,NM_144991.2:c.543-19A>G,\N,\N,3/11,Unknown significance,\N,intron_variant,1.018,0.0000168062,EXAC_NFE_AF,TSPEAR
503914,21:45951036:G>A,NM_144991.2:c.543-20C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,2.789,0.00124378,EXAC_OTH_AF,TSPEAR
503915,21:45951042:G>A,NM_144991.2:c.543-26C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,6.126,0.001,1KG_SAS_AF,TSPEAR
503916,21:45951044:G>A,NM_144991.2:c.543-28C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,7.697,0.0000172479,EXAC_NFE_AF,TSPEAR
503917,21:45951051:G>A,NM_144991.2:c.543-35C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,6.628,0.000141323,EXAC_SAS_AF,TSPEAR
503918,21:45951061:A>G,NM_144991.2:c.543-45T>C,\N,\N,3/11,Benign,\N,intron_variant,3.697,0.1785,1KG_AFR_AF,TSPEAR
503919,21:45951062:C>T,NM_144991.2:c.543-46G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,0.752,0.00138122,EXAC_OTH_AF,TSPEAR
503920,21:45951067:G>A,NM_144991.2:c.543-51C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,2.824,0.0000747943,EXAC_SAS_AF,TSPEAR
503921,21:45951074:C>T,NM_144991.2:c.543-58G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,2.428,\N,\N,TSPEAR
503922,21:45951086:A>G,NM_144991.2:c.543-70T>C,\N,\N,3/11,Benign,\N,intron_variant,1.403,0.3222,1KG_AFR_AF,TSPEAR
503923,21:45951102:CT>C,NM_144991.2:c.543-87del,\N,\N,3/11,Unknown significance,\N,intron_variant,2.141,\N,\N,TSPEAR
503924,21:45951104:A>C,NM_144991.2:c.543-88T>G,\N,\N,3/11,Unknown significance,\N,intron_variant,0.682,0.001,1KG_EUR_AF,TSPEAR
503925,21:45951107:C>T,NM_144991.2:c.543-91G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,1.733,\N,\N,TSPEAR
503926,21:45951118:T>C,NM_144991.2:c.543-102A>G,\N,\N,3/11,Benign,\N,intron_variant,0.472,0.3222,1KG_AFR_AF,TSPEAR
503927,21:45951152:G>A,NM_144991.2:c.543-136C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,3.708,\N,\N,TSPEAR
503928,21:45951160:C>T,NM_144991.2:c.543-144G>A,\N,\N,3/11,Benign,\N,intron_variant,0.549,0.007,1KG_EUR_AF,TSPEAR
503929,21:45951161:G>A,NM_144991.2:c.543-145C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,1.215,0.0014,1KG_AMR_AF,TSPEAR
503930,21:45951203:G>T,NM_144991.2:c.543-187C>A,\N,\N,3/11,Unknown significance,\N,intron_variant,2.481,\N,\N,TSPEAR
503931,21:45951205:A>G,NM_144991.2:c.543-189T>C,\N,\N,3/11,Unknown significance,\N,intron_variant,5.204,0.0015,1KG_AFR_AF,TSPEAR
503932,21:45951214:C>A,NM_144991.2:c.543-198G>T,\N,\N,3/11,Unknown significance,\N,intron_variant,6.115,0.001,1KG_EUR_AF,TSPEAR
503933,21:45951215:C>T,NM_144991.2:c.543-199G>A,\N,\N,3/11,Benign,\N,intron_variant,1.601,0.0061,1KG_SAS_AF,TSPEAR
503934,21:45951231:G>A,NM_144991.2:c.543-215C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,0.899,0.001,1KG_EUR_AF,TSPEAR
503935,21:45951235:G>A,NM_144991.2:c.543-219C>T,\N,\N,3/11,Benign,\N,intron_variant,3.096,0.0153,1KG_SAS_AF,TSPEAR
503936,21:45951242:C>T,NM_144991.2:c.543-226G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,1.813,0.001,1KG_EAS_AF,TSPEAR
503937,21:45951243:G>A,NM_144991.2:c.543-227C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,0.561,0.001,1KG_EAS_AF,TSPEAR
503938,21:45951250:C>T,NM_144991.2:c.543-234G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,5.506,0.001,1KG_EUR_AF,TSPEAR
503939,21:45951254:T>C,NM_144991.2:c.543-238A>G,\N,\N,3/11,Unknown significance,\N,intron_variant,3.768,0.0008,1KG_AFR_AF,TSPEAR
503940,21:45951264:T>G,NM_144991.2:c.543-248A>C,\N,\N,3/11,Unknown significance,\N,intron_variant,5.514,\N,\N,TSPEAR
503941,21:45951269:G>A,NM_144991.2:c.543-253C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,3.104,\N,\N,TSPEAR
503942,21:45951299:C>T,NM_144991.2:c.543-283G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,5.295,0.001,1KG_EUR_AF,TSPEAR
503943,21:45951335:A>G,NM_144991.2:c.543-319T>C,\N,\N,3/11,Unknown significance,\N,intron_variant,1.995,\N,\N,TSPEAR
503944,21:45951341:C>T,NM_144991.2:c.543-325G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,2.563,\N,\N,TSPEAR
503945,21:45951357:A>G,NM_144991.2:c.543-341T>C,\N,\N,3/11,Unknown significance,\N,intron_variant,1.586,0.001,1KG_SAS_AF,TSPEAR
503946,21:45951363:C>T,NM_144991.2:c.543-347G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,1.298,0.0014,1KG_AMR_AF,TSPEAR
503947,21:45951393:T>G,NM_144991.2:c.543-377A>C,\N,\N,3/11,Unknown significance,\N,intron_variant,4.325,0.001,1KG_EAS_AF,TSPEAR
503948,21:45951399:A>T,NM_144991.2:c.543-383T>A,\N,\N,3/11,Unknown significance,\N,intron_variant,1.295,\N,\N,TSPEAR
503949,21:45951413:G>C,NM_144991.2:c.543-397C>G,\N,\N,3/11,Benign,\N,intron_variant,3.829,0.1672,1KG_AFR_AF,TSPEAR
503950,21:45951453:T>C,NM_144991.2:c.543-437A>G,\N,\N,3/11,Benign,\N,intron_variant,1.367,0.0446,1KG_AFR_AF,TSPEAR
503951,21:45951459:C>CG,NM_144991.2:c.543-444dup,\N,\N,3/11,Benign,\N,intron_variant,3.283,0.0605,1KG_AFR_AF,TSPEAR
503952,21:45951459:C>CGG,NM_144991.2:c.543-445_543-444dup,\N,\N,3/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503953,21:45951459:C>CGGT,NM_144991.2:c.543-444_543-443insACC,\N,\N,3/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503954,21:45951459:C>CGT,NM_144991.2:c.543-444_543-443insAC,\N,\N,3/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503955,21:45951460:G>GGT,NM_144991.2:c.543-445_543-444insAC,\N,\N,3/11,Benign,\N,intron_variant,1.811,0.1964,1KG_EAS_AF,TSPEAR
503956,21:45951461:G>C,NM_144991.2:c.543-445C>G,\N,\N,3/11,Unknown significance,\N,intron_variant,0.788,\N,\N,TSPEAR
503957,21:45951462:G>T,NM_144991.2:c.543-446C>A,\N,\N,3/11,Unknown significance,\N,intron_variant,1.757,\N,\N,TSPEAR
503958,21:45951494:T>C,NM_144991.2:c.543-478A>G,\N,\N,3/11,Unknown significance,\N,intron_variant,3.58,\N,\N,TSPEAR
503959,21:45951496:C>A,NM_144991.2:c.543-480G>T,\N,\N,3/11,Unknown significance,\N,intron_variant,6.228,0.001,1KG_SAS_AF,TSPEAR
503960,21:45951504:C>T,NM_144991.2:c.543-488G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,0.881,0.0008,1KG_AFR_AF,TSPEAR
503961,21:45951529:C>A,NM_144991.2:c.543-513G>T,\N,\N,3/11,Unknown significance,\N,intron_variant,4.414,\N,\N,TSPEAR
503962,21:45951571:G>C,NM_144991.2:c.543-555C>G,\N,\N,3/11,Unknown significance,\N,intron_variant,0.993,\N,\N,TSPEAR
503963,21:45951578:C>T,NM_144991.2:c.543-562G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,4.413,0.001,1KG_EAS_AF,TSPEAR
503964,21:45951582:C>G,NM_144991.2:c.543-566G>C,\N,\N,3/11,Unknown significance,\N,intron_variant,2.885,\N,\N,TSPEAR
503965,21:45951603:A>T,NM_144991.2:c.543-587T>A,\N,\N,3/11,Unknown significance,\N,intron_variant,6.534,\N,\N,TSPEAR
503966,21:45951696:G>A,NM_144991.2:c.543-680C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,3.087,0.0015,1KG_AFR_AF,TSPEAR
503967,21:45951710:C>G,NM_144991.2:c.543-694G>C,\N,\N,3/11,Unknown significance,\N,intron_variant,0.11,\N,\N,TSPEAR
503968,21:45951713:G>T,NM_144991.2:c.543-697C>A,\N,\N,3/11,Benign,\N,intron_variant,1.819,0.0234,1KG_AFR_AF,TSPEAR
503969,21:45951717:G>A,NM_144991.2:c.543-701C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,2.877,\N,\N,TSPEAR
503970,21:45951726:C>T,NM_144991.2:c.543-710G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,2.422,\N,\N,TSPEAR
503971,21:45951727:G>A,NM_144991.2:c.543-711C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,2.959,0.001,1KG_SAS_AF,TSPEAR
503972,21:45951747:G>A,NM_144991.2:c.543-731C>T,\N,\N,3/11,Benign,\N,intron_variant,2.59,0.0368,1KG_SAS_AF,TSPEAR
503973,21:45951750:C>T,NM_144991.2:c.543-734G>A,\N,\N,3/11,Benign,\N,intron_variant,3.259,0.0112,1KG_SAS_AF,TSPEAR
503974,21:45951782:C>T,NM_144991.2:c.543-766G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,4.433,0.001,1KG_EAS_AF,TSPEAR
503975,21:45951802:C>T,NM_144991.2:c.543-786G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,6.67,0.003,1KG_EAS_AF,TSPEAR
503976,21:45951821:C>T,NM_144991.2:c.543-805G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,6.655,\N,\N,TSPEAR
503977,21:45951835:C>T,NM_144991.2:c.543-819G>A,\N,\N,3/11,Benign,\N,intron_variant,10.2,0.0363,1KG_AFR_AF,TSPEAR
503978,21:45951855:T>C,NM_144991.2:c.543-839A>G,\N,\N,3/11,Unknown significance,\N,intron_variant,3.724,0.0008,1KG_AFR_AF,TSPEAR
503979,21:45951872:G>A,NM_144991.2:c.543-856C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,13.65,0.002,1KG_EAS_AF,TSPEAR
503980,21:45951874:C>T,NM_144991.2:c.543-858G>A,\N,\N,3/11,Benign,\N,intron_variant,13.69,0.0112,1KG_SAS_AF,TSPEAR
503981,21:45951886:G>A,NM_144991.2:c.543-870C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,2.503,0.0008,1KG_AFR_AF,TSPEAR
503982,21:45951911:T>C,NM_144991.2:c.543-895A>G,\N,\N,3/11,Unknown significance,\N,intron_variant,14.74,\N,\N,TSPEAR
503983,21:45951913:T>C,NM_144991.2:c.543-897A>G,\N,\N,3/11,Benign,\N,intron_variant,14.89,0.0139,1KG_EAS_AF,TSPEAR
503984,21:45951926:C>T,NM_144991.2:c.543-910G>A,\N,\N,3/11,Benign,\N,intron_variant,11.47,0.1905,1KG_EAS_AF,TSPEAR
503985,21:45951944:C>T,NM_144991.2:c.543-928G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,12.07,0.0015,1KG_AFR_AF,TSPEAR
503986,21:45951945:G>A,NM_144991.2:c.543-929C>T,\N,\N,3/11,Benign,\N,intron_variant,12.61,0.1634,1KG_AFR_AF,TSPEAR
503987,21:45951989:G>T,NM_144991.2:c.543-973C>A,\N,\N,3/11,Unknown significance,\N,intron_variant,0.864,0.0045,1KG_AFR_AF,TSPEAR
503988,21:45951991:AC>A,NM_144991.2:c.543-976del,\N,\N,3/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503989,21:45951994:C>T,NM_144991.2:c.543-978G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,2.08,\N,\N,TSPEAR
503990,21:45951998:G>A,NM_144991.2:c.543-982C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,0.364,0.0045,1KG_AFR_AF,TSPEAR
503991,21:45951998:GTA>ATG,NM_144991.2:c.543-984_543-982delinsCAT,\N,\N,3/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
503992,21:45952000:A>G,NM_144991.2:c.543-984T>C,\N,\N,3/11,Benign,\N,intron_variant,3.708,0.9325,1KG_EAS_AF,TSPEAR
503993,21:45952008:G>A,NM_144991.2:c.543-992C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,2.075,0.0008,1KG_AFR_AF,TSPEAR
503994,21:45952014:G>C,NM_144991.2:c.543-998C>G,\N,\N,3/11,Unknown significance,\N,intron_variant,0.576,\N,\N,TSPEAR
503995,21:45952016:G>A,NM_144991.2:c.543-1000C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,3.947,\N,\N,TSPEAR
503996,21:45952027:C>T,NM_144991.2:c.543-1011G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,5.115,0.001,1KG_EAS_AF,TSPEAR
503997,21:45952028:C>T,NM_144991.2:c.543-1012G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,4.543,\N,\N,TSPEAR
503998,21:45952029:G>A,NM_144991.2:c.543-1013C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,0.038,0.0008,1KG_AFR_AF,TSPEAR
503999,21:45952039:T>A,NM_144991.2:c.543-1023A>T,\N,\N,3/11,Unknown significance,\N,intron_variant,5.051,0.0029,1KG_AMR_AF,TSPEAR
504000,21:45952078:C>T,NM_144991.2:c.543-1062G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,4.442,\N,\N,TSPEAR
504001,21:45952087:G>A,NM_144991.2:c.543-1071C>T,\N,\N,3/11,Benign,\N,intron_variant,3.942,0.1672,1KG_AFR_AF,TSPEAR
504002,21:45952105:C>T,NM_144991.2:c.543-1089G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,1.131,\N,\N,TSPEAR
504003,21:45952111:A>G,NM_144991.2:c.543-1095T>C,\N,\N,3/11,Unknown significance,\N,intron_variant,3.334,\N,\N,TSPEAR
504004,21:45952122:C>T,NM_144991.2:c.543-1106G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,4.655,\N,\N,TSPEAR
504005,21:45952126:A>T,NM_144991.2:c.543-1110T>A,\N,\N,3/11,Unknown significance,\N,intron_variant,1.317,0.0015,1KG_AFR_AF,TSPEAR
504006,21:45952133:C>T,NM_144991.2:c.543-1117G>A,\N,\N,3/11,Benign,\N,intron_variant,1.095,0.0197,1KG_AFR_AF,TSPEAR
504007,21:45952161:G>A,NM_144991.2:c.543-1145C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,3.248,0.0008,1KG_AFR_AF,TSPEAR
504008,21:45952173:C>T,NM_144991.2:c.543-1157G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,0.169,0.002,1KG_EUR_AF,TSPEAR
504009,21:45952180:C>T,NM_144991.2:c.543-1164G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,0.793,0.001,1KG_EAS_AF,TSPEAR
504010,21:45952198:C>T,NM_144991.2:c.543-1182G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,2.963,\N,\N,TSPEAR
504011,21:45952217:G>C,NM_144991.2:c.543-1201C>G,\N,\N,3/11,Unknown significance,\N,intron_variant,0.977,\N,\N,TSPEAR
504012,21:45952231:A>G,NM_144991.2:c.543-1215T>C,\N,\N,3/11,Unknown significance,\N,intron_variant,4.443,\N,\N,TSPEAR
504013,21:45952251:G>A,NM_144991.2:c.543-1235C>T,\N,\N,3/11,Benign,\N,intron_variant,2.434,0.1339,1KG_AFR_AF,TSPEAR
504014,21:45952266:T>C,NM_144991.2:c.543-1250A>G,\N,\N,3/11,Unknown significance,\N,intron_variant,1.38,0.0008,1KG_AFR_AF,TSPEAR
504015,21:45952268:T>C,NM_144991.2:c.543-1252A>G,\N,\N,3/11,Benign,\N,intron_variant,0.446,0.1641,1KG_AFR_AF,TSPEAR
504016,21:45952272:C>T,NM_144991.2:c.543-1256G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,0.372,\N,\N,TSPEAR
504017,21:45952286:G>T,NM_144991.2:c.543-1270C>A,\N,\N,3/11,Unknown significance,\N,intron_variant,0.441,\N,\N,TSPEAR
504018,21:45952288:T>C,NM_144991.2:c.543-1272A>G,\N,\N,3/11,Unknown significance,\N,intron_variant,2.518,\N,\N,TSPEAR
504019,21:45952341:C>T,NM_144991.2:c.542+1227G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,1.733,\N,\N,TSPEAR
504020,21:45952343:C>A,NM_144991.2:c.542+1225G>T,\N,\N,3/11,Unknown significance,\N,intron_variant,1.919,\N,\N,TSPEAR
504021,21:45952345:C>G,NM_144991.2:c.542+1223G>C,\N,\N,3/11,Benign,\N,intron_variant,0.935,0.0219,1KG_EUR_AF,TSPEAR
504022,21:45952362:T>G,NM_144991.2:c.542+1206A>C,\N,\N,3/11,Unknown significance,\N,intron_variant,4.61,0.002,1KG_SAS_AF,TSPEAR
504023,21:45952367:G>A,NM_144991.2:c.542+1201C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,1.118,0.002,1KG_SAS_AF,TSPEAR
504024,21:45952375:G>C,NM_144991.2:c.542+1193C>G,\N,\N,3/11,Unknown significance,\N,intron_variant,1.051,\N,\N,TSPEAR
504025,21:45952387:T>A,NM_144991.2:c.542+1181A>T,\N,\N,3/11,Unknown significance,\N,intron_variant,6.678,0.002,1KG_SAS_AF,TSPEAR
504026,21:45952390:G>A,NM_144991.2:c.542+1178C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,3.468,\N,\N,TSPEAR
504027,21:45952409:G>C,NM_144991.2:c.542+1159C>G,\N,\N,3/11,Unknown significance,\N,intron_variant,0.033,\N,\N,TSPEAR
504028,21:45952427:T>C,NM_144991.2:c.542+1141A>G,\N,\N,3/11,Benign,\N,intron_variant,2.246,0.0051,1KG_SAS_AF,TSPEAR
504029,21:45952458:C>T,NM_144991.2:c.542+1110G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,1.294,0.0008,1KG_AFR_AF,TSPEAR
504030,21:45952459:G>A,NM_144991.2:c.542+1109C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,0.197,0.0014,1KG_AMR_AF,TSPEAR
504031,21:45952474:A>G,NM_144991.2:c.542+1094T>C,\N,\N,3/11,Unknown significance,\N,intron_variant,2.257,0.003,1KG_EAS_AF,TSPEAR
504032,21:45952475:A>G,NM_144991.2:c.542+1093T>C,\N,\N,3/11,Unknown significance,\N,intron_variant,5.118,\N,\N,TSPEAR
504033,21:45952478:C>T,NM_144991.2:c.542+1090G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,1.776,0.0038,1KG_AFR_AF,TSPEAR
504034,21:45952507:C>T,NM_144991.2:c.542+1061G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,0.664,0.002,1KG_EUR_AF,TSPEAR
504035,21:45952508:G>C,NM_144991.2:c.542+1060C>G,\N,\N,3/11,Benign,\N,intron_variant,0.166,0.0106,1KG_AFR_AF,TSPEAR
504036,21:45952548:C>T,NM_144991.2:c.542+1020G>A,\N,\N,3/11,Benign,\N,intron_variant,2.484,0.0317,1KG_AMR_AF,TSPEAR
504037,21:45952553:G>A,NM_144991.2:c.542+1015C>T,\N,\N,3/11,Benign,\N,intron_variant,2.905,0.0393,1KG_AFR_AF,TSPEAR
504038,21:45952598:C>G,NM_144991.2:c.542+970G>C,\N,\N,3/11,Unknown significance,\N,intron_variant,2.387,0.0015,1KG_AFR_AF,TSPEAR
504039,21:45952603:C>T,NM_144991.2:c.542+965G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,2.651,\N,\N,TSPEAR
504040,21:45952621:C>T,NM_144991.2:c.542+947G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,0.12,\N,\N,TSPEAR
504041,21:45952644:T>A,NM_144991.2:c.542+924A>T,\N,\N,3/11,Unknown significance,\N,intron_variant,4.72,0.001,1KG_EUR_AF,TSPEAR
504042,21:45952661:G>A,NM_144991.2:c.542+907C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,4.471,0.0008,1KG_AFR_AF,TSPEAR
504043,21:45952704:C>T,NM_144991.2:c.542+864G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,1.667,\N,\N,TSPEAR
504044,21:45952741:A>G,NM_144991.2:c.542+827T>C,\N,\N,3/11,Unknown significance,\N,intron_variant,2.108,0.0014,1KG_AMR_AF,TSPEAR
504045,21:45952758:A>G,NM_144991.2:c.542+810T>C,\N,\N,3/11,Unknown significance,\N,intron_variant,8.135,\N,\N,TSPEAR
504046,21:45952759:T>C,NM_144991.2:c.542+809A>G,\N,\N,3/11,Unknown significance,\N,intron_variant,7.384,\N,\N,TSPEAR
504047,21:45952788:C>T,NM_144991.2:c.542+780G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,2.81,\N,\N,TSPEAR
504048,21:45952789:G>A,NM_144991.2:c.542+779C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,1.043,\N,\N,TSPEAR
504049,21:45952794:C>T,NM_144991.2:c.542+774G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,2.028,\N,\N,TSPEAR
504050,21:45952795:G>A,NM_144991.2:c.542+773C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,2.606,0.0023,1KG_AFR_AF,TSPEAR
504051,21:45952809:G>A,NM_144991.2:c.542+759C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,3.431,0.002,1KG_EUR_AF,TSPEAR
504052,21:45952818:C>T,NM_144991.2:c.542+750G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,1.273,0.0014,1KG_AMR_AF,TSPEAR
504053,21:45952852:G>A,NM_144991.2:c.542+716C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,4.312,0.004,1KG_EUR_AF,TSPEAR
504054,21:45952876:G>A,NM_144991.2:c.542+692C>T,\N,\N,3/11,Benign,\N,intron_variant,1.965,0.0378,1KG_AFR_AF,TSPEAR
504055,21:45952884:C>T,NM_144991.2:c.542+684G>A,\N,\N,3/11,Benign,\N,intron_variant,3.677,0.0991,1KG_AFR_AF,TSPEAR
504056,21:45952946:C>T,NM_144991.2:c.542+622G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,2.89,\N,\N,TSPEAR
504057,21:45952961:G>A,NM_144991.2:c.542+607C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,2.369,0.0008,1KG_AFR_AF,TSPEAR
504058,21:45952980:A>T,NM_144991.2:c.542+588T>A,\N,\N,3/11,Unknown significance,\N,intron_variant,3.743,0.0031,1KG_SAS_AF,TSPEAR
504059,21:45952981:C>T,NM_144991.2:c.542+587G>A,\N,\N,3/11,Benign,\N,intron_variant,4.063,0.0068,1KG_AFR_AF,TSPEAR
504060,21:45952993:C>A,NM_144991.2:c.542+575G>T,\N,\N,3/11,Unknown significance,\N,intron_variant,8.119,\N,\N,TSPEAR
504061,21:45953014:G>A,NM_144991.2:c.542+554C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,2.007,0.0015,1KG_AFR_AF,TSPEAR
504062,21:45953032:G>A,NM_144991.2:c.542+536C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,0.024,0.0023,1KG_AFR_AF,TSPEAR
504063,21:45953050:C>T,NM_144991.2:c.542+518G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,2.079,0.002,1KG_SAS_AF,TSPEAR
504064,21:45953088:G>A,NM_144991.2:c.542+480C>T,\N,\N,3/11,Benign,\N,intron_variant,0.927,0.0136,1KG_AFR_AF,TSPEAR
504065,21:45953107:T>G,NM_144991.2:c.542+461A>C,\N,\N,3/11,Unknown significance,\N,intron_variant,8.516,0.001,1KG_EAS_AF,TSPEAR
504066,21:45953115:G>A,NM_144991.2:c.542+453C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,5.571,\N,\N,TSPEAR
504067,21:45953150:A>G,NM_144991.2:c.542+418T>C,\N,\N,3/11,Benign,\N,intron_variant,0.783,0.0245,1KG_AMR_AF,TSPEAR
504068,21:45953159:C>T,NM_144991.2:c.542+409G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,3.561,\N,\N,TSPEAR
504069,21:45953169:A>T,NM_144991.2:c.542+399T>A,\N,\N,3/11,Benign,\N,intron_variant,5.528,0.1915,1KG_EAS_AF,TSPEAR
504070,21:45953218:G>A,NM_144991.2:c.542+350C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,0.178,\N,\N,TSPEAR
504071,21:45953263:T>C,NM_144991.2:c.542+305A>G,\N,\N,3/11,Unknown significance,\N,intron_variant,1.004,\N,\N,TSPEAR
504072,21:45953288:G>A,NM_144991.2:c.542+280C>T,\N,\N,3/11,Benign,\N,intron_variant,2.146,0.0749,1KG_AFR_AF,TSPEAR
504073,21:45953305:C>T,NM_144991.2:c.542+263G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,1.425,0.0008,1KG_AFR_AF,TSPEAR
504074,21:45953322:TG>T,NM_144991.2:c.542+245del,\N,\N,3/11,Unknown significance,\N,intron_variant,2.307,0.0038,1KG_AFR_AF,TSPEAR
504075,21:45953324:G>C,NM_144991.2:c.542+244C>G,\N,\N,3/11,Unknown significance,\N,intron_variant,0.462,\N,\N,TSPEAR
504076,21:45953364:T>C,NM_144991.2:c.542+204A>G,\N,\N,3/11,Unknown significance,\N,intron_variant,1.619,\N,\N,TSPEAR
504077,21:45953383:C>T,NM_144991.2:c.542+185G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,4.8,0.0023,1KG_AFR_AF,TSPEAR
504078,21:45953401:C>T,NM_144991.2:c.542+167G>A,\N,\N,3/11,Benign,\N,intron_variant,2.953,0.0089,1KG_EAS_AF,TSPEAR
504079,21:45953408:G>A,NM_144991.2:c.542+160C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,2.047,0.0014,1KG_AMR_AF,TSPEAR
504080,21:45953422:C>T,NM_144991.2:c.542+146G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,4.773,\N,\N,TSPEAR
504081,21:45953453:A>G,NM_144991.2:c.542+115T>C,\N,\N,3/11,Unknown significance,\N,intron_variant,1.583,\N,\N,TSPEAR
504082,21:45953463:C>A,NM_144991.2:c.542+105G>T,\N,\N,3/11,Benign,\N,intron_variant,4.275,0.0082,1KG_SAS_AF,TSPEAR
504083,21:45953482:T>A,NM_144991.2:c.542+86A>T,\N,\N,3/11,Unknown significance,\N,intron_variant,1.187,0.0014,1KG_AMR_AF,TSPEAR
504084,21:45953484:T>C,NM_144991.2:c.542+84A>G,\N,\N,3/11,Unknown significance,\N,intron_variant,1.221,0.0014,1KG_AMR_AF,TSPEAR
504085,21:45953490:G>A,NM_144991.2:c.542+78C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,0.708,0.0031,1KG_SAS_AF,TSPEAR
504086,21:45953493:G>A,NM_144991.2:c.542+75C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,1.618,0.0023,1KG_AFR_AF,TSPEAR
504087,21:45953493:G>T,NM_144991.2:c.542+75C>A,\N,\N,3/11,Benign,\N,intron_variant,0.561,0.0061,1KG_AFR_AF,TSPEAR
504088,21:45953499:G>A,NM_144991.2:c.542+69C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,1.699,\N,\N,TSPEAR
504089,21:45953530:G>C,NM_144991.2:c.542+38C>G,\N,\N,3/11,Unknown significance,\N,intron_variant,0.652,0.0045,1KG_AFR_AF,TSPEAR
504090,21:45953532:G>T,NM_144991.2:c.542+36C>A,\N,\N,3/11,Unknown significance,\N,intron_variant,2.262,0.0000184781,EXAC_NFE_AF,TSPEAR
504091,21:45953533:G>T,NM_144991.2:c.542+35C>A,\N,\N,3/11,Unknown significance,\N,intron_variant,1.344,0.000133476,EXAC_EAS_AF,TSPEAR
504092,21:45953538:C>A,NM_144991.2:c.542+30G>T,\N,\N,3/11,Unknown significance,\N,intron_variant,4.144,0.000722245,EXAC_AMR_AF,TSPEAR
504093,21:45953543:G>A,NM_144991.2:c.542+25C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,3.143,0.000322373,EXAC_SAS_AF,TSPEAR
504094,21:45953548:C>G,NM_144991.2:c.542+20G>C,\N,\N,3/11,Unknown significance,\N,intron_variant,2.953,0.000018078,EXAC_NFE_AF,TSPEAR
504095,21:45953553:C>T,NM_144991.2:c.542+15G>A,\N,\N,3/11,Unknown significance,\N,intron_variant,1.727,0.00117096,EXAC_EAS_AF,TSPEAR
504096,21:45953554:G>A,NM_144991.2:c.542+14C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,1.289,0.0045,1KG_AFR_AF,TSPEAR
504097,21:45953556:G>A,NM_144991.2:c.542+12C>T,\N,\N,3/11,Unknown significance,\N,intron_variant,1.584,0.0000988728,EXAC_AMR_AF,TSPEAR
504098,21:45953565:T>A,NM_144991.2:c.542+3A>T,\N,\N,3/11,Unknown significance,\N,splice_region_variant&intron_variant,8.24,0.000761228,EXAC_EAS_AF,TSPEAR
504099,21:45953568:A>C,NM_144991.2:c.542T>G,NP_659428.2:p.Ile181Arg,3/12,\N,Unknown significance,\N,missense_variant&splice_region_variant,19.01,0.000385951,EXAC_FIN_AF,TSPEAR
504100,21:45953569:T>TG,NM_144991.2:c.540dup,NP_659428.2:p.Ile181HisfsTer76,3/12,\N,Unknown significance,\N,frameshift_variant&splice_region_variant,28.1,0.00036049,EXAC_AFR_AF,TSPEAR
504101,21:45953571:T>A,NM_144991.2:c.539A>T,NP_659428.2:p.Asp180Val,3/12,\N,Unknown significance,\N,missense_variant,15.71,0.000251004,EXAC_EAS_AF,TSPEAR
504102,21:45953572:C>T,NM_144991.2:c.538G>A,NP_659428.2:p.Asp180Asn,3/12,\N,Unknown significance,\N,missense_variant,17.02,0.0013369,EXAC_OTH_AF,TSPEAR
504103,21:45953573:C>T,NM_144991.2:c.537G>A,NP_659428.2:p.Val179=,3/12,\N,Unknown significance,\N,synonymous_variant,7.853,0.000375188,EXAC_EAS_AF,TSPEAR
504104,21:45953574:A>G,NM_144991.2:c.536T>C,NP_659428.2:p.Val179Ala,3/12,\N,Likely benign,\N,missense_variant,8.037,0.0000170369,EXAC_NFE_AF,TSPEAR
504105,21:45953576:C>T,NM_144991.2:c.534G>A,NP_659428.2:p.Pro178=,3/12,\N,Benign,\N,synonymous_variant,11.23,0.0275479,EXAC_AFR_AF,TSPEAR
504106,21:45953577:G>A,NM_144991.2:c.533C>T,NP_659428.2:p.Pro178Leu,3/12,\N,Unknown significance,\N,missense_variant,27.1,0.0000652486,EXAC_SAS_AF,TSPEAR
504107,21:45953581:G>A,NM_144991.2:c.529C>T,NP_659428.2:p.Leu177Phe,3/12,\N,Likely benign,\N,missense_variant,4.66,\N,\N,TSPEAR
504108,21:45953584:C>T,NM_144991.2:c.526G>A,NP_659428.2:p.Gly176Ser,3/12,\N,Unknown significance,\N,missense_variant,14.22,0.002,1KG_EAS_AF|1KG_EUR_AF,TSPEAR
504109,21:45953585:G>A,NM_144991.2:c.525C>T,NP_659428.2:p.Cys175=,3/12,\N,Unknown significance,\N,synonymous_variant,5.649,0.0014,1KG_AMR_AF,TSPEAR
504110,21:45953586:C>A,NM_144991.2:c.524G>T,NP_659428.2:p.Cys175Phe,3/12,\N,Unknown significance,\N,missense_variant,27.7,\N,\N,TSPEAR
504111,21:45953587:A>G,NM_144991.2:c.523T>C,NP_659428.2:p.Cys175Arg,3/12,\N,Unknown significance,\N,missense_variant,25.1,0.0000166014,EXAC_NFE_AF,TSPEAR
504112,21:45953590:C>G,NM_144991.2:c.520G>C,NP_659428.2:p.Asp174His,3/12,\N,Unknown significance,\N,missense_variant,25.6,0.0000909587,EXAC_AMR_AF,TSPEAR
504113,21:45953591:C>T,NM_144991.2:c.519G>A,NP_659428.2:p.Thr173=,3/12,\N,Unknown significance,\N,synonymous_variant,12.62,0.0000661726,EXAC_NFE_AF,TSPEAR
504114,21:45953592:G>A,NM_001272037.1:c.314C>T,NP_001258966.1:p.Thr105Met,4/13,\N,Likely benign,\N,missense_variant,14.64,0.001,1KG_SAS_AF,TSPEAR
504115,21:45953603:G>A,NM_144991.2:c.507C>T,NP_659428.2:p.Phe169=,3/12,\N,Unknown significance,\N,synonymous_variant,3.322,0.0000163554,EXAC_NFE_AF,TSPEAR
504116,21:45953604:A>G,NM_144991.2:c.506T>C,NP_659428.2:p.Phe169Ser,3/12,\N,Unknown significance,\N,missense_variant,14.82,0.0000163409,EXAC_NFE_AF,TSPEAR
504117,21:45953606:G>A,NM_144991.2:c.504C>T,NP_659428.2:p.Val168=,3/12,\N,Unknown significance,\N,synonymous_variant,6.404,0.0000163292,EXAC_NFE_AF,TSPEAR
504118,21:45953608:C>T,NM_144991.2:c.502G>A,NP_659428.2:p.Val168Ile,3/12,\N,Likely benign,\N,missense_variant,0.023,0.002,1KG_SAS_AF,TSPEAR
504119,21:45953609:G>A,NM_144991.2:c.501C>T,NP_659428.2:p.Gly167=,3/12,\N,Unknown significance,\N,synonymous_variant,7.947,0.0043,1KG_AMR_AF,TSPEAR
504120,21:45953611:C>T,NM_144991.2:c.499G>A,NP_659428.2:p.Gly167Ser,3/12,\N,Likely benign,\N,missense_variant,1.048,0.0000975991,EXAC_NFE_AF,TSPEAR
504121,21:45953614:C>T,NM_144991.2:c.496G>A,NP_659428.2:p.Ala166Thr,3/12,\N,Likely benign,\N,missense_variant,10.62,0.0000616295,EXAC_SAS_AF,TSPEAR
504122,21:45953615:G>A,NM_144991.2:c.495C>T,NP_659428.2:p.Ser165=,3/12,\N,Unknown significance,\N,synonymous_variant,4.078,0.000110181,EXAC_AFR_AF,TSPEAR
504123,21:45953617:A>G,NM_144991.2:c.493T>C,NP_659428.2:p.Ser165Pro,3/12,\N,Unknown significance,\N,missense_variant,18.87,0.0008,1KG_AFR_AF,TSPEAR
504124,21:45953624:C>A,NM_144991.2:c.486G>T,NP_659428.2:p.Leu162=,3/12,\N,Unknown significance,\N,synonymous_variant,6.529,0.000119048,EXAC_EAS_AF,TSPEAR
504125,21:45953642:G>A,NM_144991.2:c.468C>T,NP_659428.2:p.Arg156=,3/12,\N,Unknown significance,\N,synonymous_variant,1.091,0.000353982,EXAC_AMR_AF,TSPEAR
504126,21:45953643:C>T,NM_144991.2:c.467G>A,NP_659428.2:p.Arg156His,3/12,\N,Likely benign,\N,missense_variant,8.365,0.000244379,EXAC_SAS_AF,TSPEAR
504127,21:45953644:G>A,NM_144991.2:c.466C>T,NP_659428.2:p.Arg156Cys,3/12,\N,Unknown significance,\N,missense_variant,23.9,0.001,1KG_EAS_AF,TSPEAR
504128,21:45953648:A>G,NM_144991.2:c.462T>C,NP_659428.2:p.Asp154=,3/12,\N,Unknown significance,\N,synonymous_variant,0.097,0.0000160395,EXAC_NFE_AF,TSPEAR
504129,21:45953649:TC>T,NM_144991.2:c.460del,NP_659428.2:p.Asp154MetfsTer28,3/12,\N,Unknown significance,\N,frameshift_variant,28,\N,\N,TSPEAR
504130,21:45953654:C>G,NM_144991.2:c.456G>C,NP_659428.2:p.Leu152=,3/12,\N,Unknown significance,\N,synonymous_variant,0.808,0.0000160467,EXAC_NFE_AF,TSPEAR
504131,21:45953657:G>A,NM_144991.2:c.453C>T,NP_659428.2:p.Ala151=,3/12,\N,Unknown significance,\N,synonymous_variant,2.034,0.000116686,EVS_EA_AF,TSPEAR
504132,21:45953660:C>T,NM_144991.2:c.450G>A,NP_659428.2:p.Pro150=,3/12,\N,Unknown significance,\N,synonymous_variant,10.58,0.0000320595,EXAC_NFE_AF,TSPEAR
504133,21:45953661:G>A,NM_144991.2:c.449C>T,NP_659428.2:p.Pro150Leu,3/12,\N,Likely benign,\N,missense_variant,8.225,0.0008,1KG_AFR_AF,TSPEAR
504134,21:45953664:C>G,NM_144991.2:c.446G>C,NP_659428.2:p.Ser149Thr,3/12,\N,Likely benign,\N,missense_variant,0.047,0.0000609682,EXAC_SAS_AF,TSPEAR
504135,21:45953668:G>A,NM_144991.2:c.442C>T,NP_659428.2:p.Arg148Cys,3/12,\N,Unknown significance,\N,missense_variant,25.8,0.000107204,EXAC_AFR_AF,TSPEAR
504136,21:45953673:G>A,NM_144991.2:c.437C>T,NP_659428.2:p.Ser146Phe,3/12,\N,Unknown significance,\N,missense_variant,25,0.000121877,EXAC_SAS_AF,TSPEAR
504137,21:45953679:C>A,NM_144991.2:c.431G>T,NP_659428.2:p.Arg144Leu,3/12,\N,Unknown significance,\N,missense_variant,22.9,0.0000159724,EXAC_NFE_AF,TSPEAR
504138,21:45953679:C>T,NM_144991.2:c.431G>A,NP_659428.2:p.Arg144Gln,3/12,\N,Likely benign,\N,missense_variant,22.5,0.00256138,EXAC_AMR_AF,TSPEAR
504139,21:45953680:G>A,NM_144991.2:c.430C>T,NP_659428.2:p.Arg144Ter,3/12,\N,Unknown significance,\N,stop_gained,36,0.000355366,EXAC_EAS_AF,TSPEAR
504140,21:45953691:G>T,NM_144991.2:c.419C>A,NP_659428.2:p.Ala140Asp,3/12,\N,Likely benign,\N,missense_variant,12.14,0.000910332,EVS_AA_AF,TSPEAR
504141,21:45953692:C>T,NM_144991.2:c.418G>A,NP_659428.2:p.Ala140Thr,3/12,\N,Likely benign,\N,missense_variant,15.99,0.0022952,EXAC_AMR_AF,TSPEAR
504142,21:45953693:G>A,NM_144991.2:c.417C>T,NP_659428.2:p.Gly139=,3/12,\N,Unknown significance,\N,synonymous_variant,8.593,0.000121773,EXAC_SAS_AF,TSPEAR
504143,21:45953695:C>T,NM_144991.2:c.415G>A,NP_659428.2:p.Gly139Ser,3/12,\N,Benign,\N,missense_variant,12.1,0.00661504,EXAC_FIN_AF,TSPEAR
504144,21:45953696:G>A,NM_144991.2:c.414C>T,NP_659428.2:p.Ala138=,3/12,\N,Unknown significance,\N,synonymous_variant,9.012,0.0000608643,EXAC_SAS_AF,TSPEAR
504145,21:45953696:G>T,NM_144991.2:c.414C>A,NP_659428.2:p.Ala138=,3/12,\N,Unknown significance,\N,synonymous_variant,6.736,0.000161394,EXAC_FIN_AF,TSPEAR
504146,21:45953699:C>T,NM_144991.2:c.411G>A,NP_659428.2:p.Thr137=,3/12,\N,Unknown significance,\N,synonymous_variant,11.37,0.00158266,EXAC_SAS_AF,TSPEAR
504147,21:45953700:G>A,NM_144991.2:c.410C>T,NP_659428.2:p.Thr137Met,3/12,\N,Likely benign,\N,missense_variant,0.754,0.0000317521,EXAC_NFE_AF,TSPEAR
504148,21:45953706:T>G,NM_144991.2:c.404A>C,NP_659428.2:p.Glu135Ala,3/12,\N,Likely benign,\N,missense_variant,0.021,0.0000608273,EXAC_SAS_AF,TSPEAR
504149,21:45953707:C>T,NM_144991.2:c.403G>A,NP_659428.2:p.Glu135Lys,3/12,\N,Likely benign,\N,missense_variant,2.136,0.000209776,EXAC_AFR_AF,TSPEAR
504150,21:45953708:G>A,NM_144991.2:c.402C>T,NP_659428.2:p.Arg134=,3/12,\N,Unknown significance,\N,synonymous_variant,7.362,0.00119617,EXAC_OTH_AF,TSPEAR
504151,21:45953709:C>A,NM_001272037.1:c.197G>T,NP_001258966.1:p.Arg66Leu,4/13,\N,Likely benign,\N,missense_variant,12.5,0.0000881679,EXAC_AMR_AF,TSPEAR
504152,21:45953709:C>T,NM_144991.2:c.401G>A,NP_659428.2:p.Arg134His,3/12,\N,Likely benign,\N,missense_variant,11.57,0.000243368,EXAC_SAS_AF,TSPEAR
504153,21:45953710:G>A,NM_144991.2:c.400C>T,NP_659428.2:p.Arg134Cys,3/12,\N,Likely benign,\N,missense_variant,7.052,0.001,1KG_EUR_AF,TSPEAR
504154,21:45953713:G>A,NM_144991.2:c.397C>T,NP_659428.2:p.Leu133Phe,3/12,\N,Likely benign,\N,missense_variant,0.304,0.0000158123,EXAC_NFE_AF,TSPEAR
504155,21:45953716:A>G,NM_144991.2:c.394T>C,NP_659428.2:p.Phe132Leu,3/12,\N,Unknown significance,\N,missense_variant,17.09,0.00011636,EVS_EA_AF,TSPEAR
504156,21:45953735:A>C,NM_144991.2:c.375T>G,NP_659428.2:p.Pro125=,3/12,\N,Unknown significance,\N,synonymous_variant,0.005,0.0000882924,EXAC_AMR_AF,TSPEAR
504157,21:45953744:C>T,NM_144991.2:c.366G>A,NP_659428.2:p.Arg122=,3/12,\N,Unknown significance,\N,synonymous_variant,4.096,0.0000158484,EXAC_NFE_AF,TSPEAR
504158,21:45953745:C>T,NM_144991.2:c.365G>A,NP_659428.2:p.Arg122Gln,3/12,\N,Unknown significance,\N,missense_variant,29.1,0.00204732,EVS_AA_AF,TSPEAR
504159,21:45953746:G>A,NM_144991.2:c.364C>T,NP_659428.2:p.Arg122Trp,3/12,\N,Unknown significance,\N,missense_variant,27,0.00146843,EXAC_AFR_AF,TSPEAR
504160,21:45953748:A>G,NM_144991.2:c.362T>C,NP_659428.2:p.Leu121Pro,3/12,\N,Unknown significance,\N,missense_variant,24.4,0.0016832,EXAC_AMR_AF,TSPEAR
504161,21:45953751:C>T,NM_144991.2:c.359G>A,NP_659428.2:p.Gly120Asp,3/12,\N,Unknown significance,\N,missense_variant,24.8,\N,\N,TSPEAR
504162,21:45953752:C>T,NM_144991.2:c.358G>A,NP_659428.2:p.Gly120Ser,3/12,\N,Unknown significance,\N,missense_variant,23.6,0.001,1KG_SAS_AF,TSPEAR
504163,21:45953753:G>A,NM_144991.2:c.357C>T,NP_659428.2:p.Leu119=,3/12,\N,Unknown significance,\N,synonymous_variant,1.473,0.0008,1KG_AFR_AF,TSPEAR
504164,21:45953755:G>A,NM_144991.2:c.355C>T,NP_659428.2:p.Leu119Phe,3/12,\N,Unknown significance,\N,missense_variant,24.3,0.000573833,EXAC_NFE_AF,TSPEAR
504165,21:45953756:C>A,NM_144991.2:c.354G>T,NP_659428.2:p.Leu118=,3/12,\N,Unknown significance,\N,synonymous_variant,11.71,\N,\N,TSPEAR
504166,21:45953756:C>T,NM_144991.2:c.354G>A,NP_659428.2:p.Leu118=,3/12,\N,Unknown significance,\N,synonymous_variant,8.245,0.000366394,EXAC_NFE_AF,TSPEAR
504167,21:45953764:G>A,NM_144991.2:c.346C>T,NP_659428.2:p.Leu116=,3/12,\N,Unknown significance,\N,synonymous_variant,0.517,0.00245098,EXAC_OTH_AF,TSPEAR
504168,21:45953765:G>A,NM_144991.2:c.345C>T,NP_659428.2:p.Asp115=,3/12,\N,Unknown significance,\N,synonymous_variant,1.379,0.000227894,EVS_AA_AF,TSPEAR
504169,21:45953767:C>T,NM_144991.2:c.343G>A,NP_659428.2:p.Asp115Asn,3/12,\N,Likely benign,\N,missense_variant,9.142,0.00455789,EVS_AA_AF,TSPEAR
504170,21:45953768:G>A,NM_144991.2:c.342C>T,NP_659428.2:p.Ser114=,3/12,\N,Unknown significance,\N,synonymous_variant,6.73,0.000106883,EXAC_AFR_AF,TSPEAR
504171,21:45953769:C>T,NM_144991.2:c.341G>A,NP_659428.2:p.Ser114Asn,3/12,\N,Likely benign,\N,missense_variant,5.23,\N,\N,TSPEAR
504172,21:45953773:C>T,NM_144991.2:c.337G>A,NP_659428.2:p.Glu113Lys,3/12,\N,Benign,\N,missense_variant,13.15,0.006,1KG_EUR_AF,TSPEAR
504173,21:45953786:C>T,NM_144991.2:c.324G>A,NP_659428.2:p.Thr108=,3/12,\N,Unknown significance,\N,synonymous_variant,11.16,0.00012604,EXAC_SAS_AF,TSPEAR
504174,21:45953787:G>A,NM_144991.2:c.323C>T,NP_659428.2:p.Thr108Met,3/12,\N,Unknown significance,\N,missense_variant,24.6,0.000126231,EXAC_SAS_AF,TSPEAR
504175,21:45953800:C>T,NM_144991.2:c.310G>A,NP_659428.2:p.Glu104Lys,3/12,\N,Unknown significance,\N,missense_variant,24.8,0.0000169256,EXAC_NFE_AF,TSPEAR
504176,21:45953801:G>A,NM_144991.2:c.309C>T,NP_659428.2:p.Asn103=,3/12,\N,Unknown significance,\N,synonymous_variant,9.167,0.000116036,EXAC_AFR_AF,TSPEAR
504177,21:45953804:C>T,NM_144991.2:c.306G>A,NP_659428.2:p.Arg102=,3/12,\N,Unknown significance,\N,splice_region_variant&synonymous_variant,12.89,0.000117123,EXAC_AFR_AF,TSPEAR
504178,21:45953807:C>G,NM_144991.2:c.304-1G>C,\N,\N,2/11,Unknown significance,\N,splice_acceptor_variant,23.8,0.0000350177,EXAC_NFE_AF,TSPEAR
504179,21:45953817:C>G,NM_144991.2:c.304-11G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.13,0.0000182729,EXAC_NFE_AF,TSPEAR
504180,21:45953817:C>T,NM_144991.2:c.304-11G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.412,0.000420875,EXAC_SAS_AF,TSPEAR
504181,21:45953818:G>A,NM_144991.2:c.304-12C>T,\N,\N,2/11,Benign,\N,intron_variant,3.865,0.00538324,EXAC_AFR_AF,TSPEAR
504182,21:45953818:G>C,NM_144991.2:c.304-12C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.242,0.0000183655,EXAC_NFE_AF,TSPEAR
504183,21:45953821:C>T,NM_144991.2:c.304-15G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,5.926,0.000142714,EXAC_SAS_AF,TSPEAR
504184,21:45953825:G>A,NM_144991.2:c.304-19C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.539,0.0008,1KG_AFR_AF,TSPEAR
504185,21:45953829:A>C,NM_144991.2:c.304-23T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.292,0.000111408,EXAC_AMR_AF,TSPEAR
504186,21:45953829:A>G,NM_144991.2:c.304-23T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,3.066,0.000158341,EXAC_NFE_AF,TSPEAR
504187,21:45953830:G>A,NM_144991.2:c.304-24C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.081,0.00014979,EXAC_EAS_AF,TSPEAR
504188,21:45953833:C>T,NM_144991.2:c.304-27G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,6.646,0.00136945,EXAC_EAS_AF,TSPEAR
504189,21:45953834:G>A,NM_144991.2:c.304-28C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,6.915,0.00162338,EXAC_OTH_AF,TSPEAR
504190,21:45953838:C>CTGGGGG,NM_144991.2:c.304-38_304-33dup,\N,\N,2/11,Unknown significance,\N,intron_variant,2.107,0.000237042,EXAC_SAS_AF,TSPEAR
504191,21:45953842:G>C,NM_144991.2:c.304-36C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,5.6,0.000507442,EXAC_AFR_AF,TSPEAR
504192,21:45953843:G>A,NM_144991.2:c.304-37C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,8.135,\N,\N,TSPEAR
504193,21:45953844:G>A,NM_144991.2:c.304-38C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,7.952,0.0008,1KG_AFR_AF,TSPEAR
504194,21:45953852:C>T,NM_144991.2:c.304-46G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.776,0.000105552,EXAC_SAS_AF,TSPEAR
504195,21:45953853:G>A,NM_144991.2:c.304-47C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.014,0.00224341,EXAC_EAS_AF,TSPEAR
504196,21:45953858:C>T,NM_144991.2:c.304-52G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,5.582,0.001,1KG_EUR_AF,TSPEAR
504197,21:45953859:G>A,NM_144991.2:c.304-53C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.535,\N,\N,TSPEAR
504198,21:45953866:G>A,NM_144991.2:c.304-60C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,4.145,0.002,1KG_EUR_AF,TSPEAR
504199,21:45953880:G>A,NM_144991.2:c.304-74C>T,\N,\N,2/11,Benign,\N,intron_variant,4.863,0.0115,1KG_AMR_AF,TSPEAR
504200,21:45953895:C>T,NM_144991.2:c.304-89G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,5.616,\N,\N,TSPEAR
504201,21:45953909:G>A,NM_144991.2:c.304-103C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.554,0.001,1KG_EAS_AF,TSPEAR
504202,21:45953932:C>T,NM_144991.2:c.304-126G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,6.593,0.0008,1KG_AFR_AF,TSPEAR
504203,21:45953933:G>A,NM_144991.2:c.304-127C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.631,0.002,1KG_EUR_AF|1KG_SAS_AF,TSPEAR
504204,21:45953945:C>T,NM_144991.2:c.304-139G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.391,0.0023,1KG_AFR_AF,TSPEAR
504205,21:45953948:G>A,NM_144991.2:c.304-142C>T,\N,\N,2/11,Benign,\N,intron_variant,2.72,0.0227,1KG_AFR_AF,TSPEAR
504206,21:45954008:T>TG,NM_144991.2:c.304-203dup,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
504207,21:45954104:G>T,NM_144991.2:c.304-298C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.127,\N,\N,TSPEAR
504208,21:45954110:T>A,NM_144991.2:c.304-304A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.614,\N,\N,TSPEAR
504209,21:45954177:C>G,NM_144991.2:c.304-371G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.152,0.0043,1KG_AMR_AF,TSPEAR
504210,21:45954178:A>G,NM_144991.2:c.304-372T>C,\N,\N,2/11,Benign,\N,intron_variant,1.433,0.0182,1KG_AFR_AF,TSPEAR
504211,21:45954197:C>G,NM_144991.2:c.304-391G>C,\N,\N,2/11,Benign,\N,intron_variant,0.174,0.0212,1KG_AFR_AF,TSPEAR
504212,21:45954198:A>G,NM_144991.2:c.304-392T>C,\N,\N,2/11,Benign,\N,intron_variant,0.23,0.0144,1KG_AFR_AF,TSPEAR
504213,21:45954238:C>G,NM_144991.2:c.304-432G>C,\N,\N,2/11,Benign,\N,intron_variant,1.7,0.0069,1KG_EAS_AF,TSPEAR
504214,21:45954253:C>G,NM_144991.2:c.304-447G>C,\N,\N,2/11,Benign,\N,intron_variant,0.139,0.0076,1KG_AFR_AF,TSPEAR
504215,21:45954254:A>G,NM_144991.2:c.304-448T>C,\N,\N,2/11,Benign,\N,intron_variant,1.077,0.0053,1KG_AFR_AF,TSPEAR
504216,21:45954268:A>T,NM_144991.2:c.304-462T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.495,0.003,1KG_EUR_AF,TSPEAR
504217,21:45954273:T>C,NM_144991.2:c.304-467A>G,\N,\N,2/11,Benign,\N,intron_variant,1.261,0.0068,1KG_AFR_AF,TSPEAR
504218,21:45954273:T>G,NM_144991.2:c.304-467A>C,\N,\N,2/11,Benign,\N,intron_variant,2.533,0.0628,1KG_AFR_AF,TSPEAR
504219,21:45954274:G>A,NM_144991.2:c.304-468C>T,\N,\N,2/11,Benign,\N,intron_variant,1.952,0.0068,1KG_AFR_AF,TSPEAR
504220,21:45954288:A>T,NM_144991.2:c.304-482T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.037,\N,\N,TSPEAR
504221,21:45954293:C>T,NM_144991.2:c.304-487G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.789,\N,\N,TSPEAR
504222,21:45954363:A>G,NM_144991.2:c.304-557T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.389,\N,\N,TSPEAR
504223,21:45954377:A>G,NM_144991.2:c.304-571T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.561,\N,\N,TSPEAR
504224,21:45954427:G>A,NM_144991.2:c.304-621C>T,\N,\N,2/11,Benign,\N,intron_variant,4.214,0.008,1KG_EUR_AF,TSPEAR
504225,21:45954452:C>T,NM_144991.2:c.304-646G>A,\N,\N,2/11,Benign,\N,intron_variant,6.289,0.0153,1KG_SAS_AF,TSPEAR
504226,21:45954453:G>A,NM_144991.2:c.304-647C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.999,0.003,1KG_EAS_AF,TSPEAR
504227,21:45954479:C>A,NM_144991.2:c.304-673G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,7.636,\N,\N,TSPEAR
504228,21:45954493:A>T,NM_144991.2:c.304-687T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.849,\N,\N,TSPEAR
504229,21:45954503:C>G,NM_144991.2:c.304-697G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.162,0.0043,1KG_AMR_AF,TSPEAR
504230,21:45954507:A>G,NM_144991.2:c.304-701T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.294,\N,\N,TSPEAR
504231,21:45954535:C>T,NM_144991.2:c.304-729G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.376,0.001,1KG_SAS_AF,TSPEAR
504232,21:45954554:C>T,NM_144991.2:c.304-748G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.148,0.0014,1KG_AMR_AF,TSPEAR
504233,21:45954572:G>C,NM_144991.2:c.304-766C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.485,\N,\N,TSPEAR
504234,21:45954624:A>C,NM_144991.2:c.304-818T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.101,0.0008,1KG_AFR_AF,TSPEAR
504235,21:45954639:G>A,NM_144991.2:c.304-833C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.194,0.0014,1KG_AMR_AF,TSPEAR
504236,21:45954663:T>G,NM_144991.2:c.304-857A>C,\N,\N,2/11,Unknown significance,\N,intron_variant,7.81,\N,\N,TSPEAR
504237,21:45954688:G>A,NM_144991.2:c.304-882C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,6.687,0.003,1KG_EAS_AF,TSPEAR
504238,21:45954697:A>C,NM_144991.2:c.304-891T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.033,0.0014,1KG_AMR_AF,TSPEAR
504239,21:45954755:C>G,NM_144991.2:c.304-949G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.923,\N,\N,TSPEAR
504240,21:45954769:C>T,NM_144991.2:c.304-963G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.9,0.001,1KG_EUR_AF,TSPEAR
504241,21:45954774:G>A,NM_144991.2:c.304-968C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.437,\N,\N,TSPEAR
504242,21:45954785:C>T,NM_144991.2:c.304-979G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.3,0.001,1KG_EAS_AF,TSPEAR
504243,21:45954786:G>A,NM_144991.2:c.304-980C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.98,0.0008,1KG_AFR_AF,TSPEAR
504244,21:45954800:CCA>C,NM_144991.2:c.304-996_304-995del,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
504245,21:45954806:A>G,NM_144991.2:c.304-1000T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.149,\N,\N,TSPEAR
504246,21:45954816:TAGTC>T,NM_144991.2:c.304-1014_304-1011del,\N,\N,2/11,Unknown significance,\N,intron_variant,6.53,0.003,1KG_AFR_AF,TSPEAR
504247,21:45954851:A>T,NM_144991.2:c.304-1045T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.357,0.0008,1KG_AFR_AF,TSPEAR
504248,21:45954871:C>T,NM_144991.2:c.304-1065G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.359,0.002,1KG_EAS_AF,TSPEAR
504249,21:45954886:C>T,NM_144991.2:c.304-1080G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.101,0.001,1KG_EAS_AF,TSPEAR
504250,21:45954898:C>T,NM_144991.2:c.304-1092G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.726,0.002,1KG_SAS_AF,TSPEAR
504251,21:45954943:T>C,NM_144991.2:c.304-1137A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.471,\N,\N,TSPEAR
504252,21:45954950:G>A,NM_144991.2:c.304-1144C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.182,\N,\N,TSPEAR
504253,21:45954969:T>A,NM_144991.2:c.304-1163A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,4.92,\N,\N,TSPEAR
504254,21:45954985:G>A,NM_144991.2:c.304-1179C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.658,0.0014,1KG_AMR_AF,TSPEAR
504255,21:45955007:C>T,NM_144991.2:c.304-1201G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.141,0.001,1KG_EAS_AF,TSPEAR
504256,21:45955039:G>A,NM_144991.2:c.304-1233C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.319,\N,\N,TSPEAR
504257,21:45955077:GTA>G,NM_144991.2:c.304-1273_304-1272del,\N,\N,2/11,Benign,\N,intron_variant,5.404,0.0303,1KG_AFR_AF,TSPEAR
504258,21:45955090:T>G,NM_144991.2:c.304-1284A>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.657,0.003,1KG_EAS_AF,TSPEAR
504259,21:45955096:C>T,NM_144991.2:c.304-1290G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.42,\N,\N,TSPEAR
504260,21:45955147:C>G,NM_144991.2:c.304-1341G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.025,0.0041,1KG_SAS_AF,TSPEAR
504261,21:45955147:C>T,NM_144991.2:c.304-1341G>A,\N,\N,2/11,Benign,\N,intron_variant,0.054,0.0234,1KG_AFR_AF,TSPEAR
504262,21:45955148:G>A,NM_144991.2:c.304-1342C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.693,0.001,1KG_SAS_AF,TSPEAR
504263,21:45955152:A>G,NM_144991.2:c.304-1346T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.321,0.0008,1KG_AFR_AF,TSPEAR
504264,21:45955154:A>C,NM_144991.2:c.304-1348T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.151,\N,\N,TSPEAR
504265,21:45955162:T>C,NM_144991.2:c.304-1356A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.486,\N,\N,TSPEAR
504266,21:45955171:A>G,NM_144991.2:c.304-1365T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.343,\N,\N,TSPEAR
504267,21:45955182:C>A,NM_144991.2:c.304-1376G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,4.53,0.001,1KG_EAS_AF,TSPEAR
504268,21:45955214:G>T,NM_144991.2:c.304-1408C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.345,0.001,1KG_SAS_AF,TSPEAR
504269,21:45955228:G>C,NM_144991.2:c.304-1422C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.573,0.0015,1KG_AFR_AF,TSPEAR
504270,21:45955245:A>G,NM_144991.2:c.304-1439T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.23,0.001,1KG_EUR_AF,TSPEAR
504271,21:45955286:T>C,NM_144991.2:c.304-1480A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.608,0.0008,1KG_AFR_AF,TSPEAR
504272,21:45955301:C>T,NM_144991.2:c.304-1495G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.991,\N,\N,TSPEAR
504273,21:45955309:G>T,NM_144991.2:c.304-1503C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.587,0.0008,1KG_AFR_AF,TSPEAR
504274,21:45955325:A>G,NM_144991.2:c.304-1519T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.373,0.001,1KG_EAS_AF,TSPEAR
504275,21:45955352:C>T,NM_144991.2:c.304-1546G>A,\N,\N,2/11,Benign,\N,intron_variant,0.892,0.0051,1KG_SAS_AF,TSPEAR
504276,21:45955353:G>A,NM_144991.2:c.304-1547C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.488,\N,\N,TSPEAR
504277,21:45955364:G>A,NM_144991.2:c.304-1558C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.562,0.003,1KG_AFR_AF,TSPEAR
504278,21:45955372:T>C,NM_144991.2:c.304-1566A>G,\N,\N,2/11,Benign,\N,intron_variant,0.406,0.4939,1KG_AFR_AF,TSPEAR
504279,21:45955380:G>T,NM_144991.2:c.304-1574C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.014,\N,\N,TSPEAR
504280,21:45955422:C>T,NM_144991.2:c.304-1616G>A,\N,\N,2/11,Benign,\N,intron_variant,0.721,0.007,1KG_EUR_AF,TSPEAR
504281,21:45955456:G>A,NM_144991.2:c.304-1650C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.944,\N,\N,TSPEAR
504282,21:45955458:A>G,NM_144991.2:c.304-1652T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,5.589,0.0029,1KG_AMR_AF,TSPEAR
504283,21:45955463:CTGTT>C,NM_144991.2:c.304-1661_304-1658del,\N,\N,2/11,Unknown significance,\N,intron_variant,5.828,0.0038,1KG_AFR_AF,TSPEAR
504284,21:45955478:G>A,NM_144991.2:c.304-1672C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,8.582,0.0008,1KG_AFR_AF,TSPEAR
504285,21:45955505:G>A,NM_144991.2:c.304-1699C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.502,\N,\N,TSPEAR
504286,21:45955531:C>T,NM_144991.2:c.304-1725G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.446,\N,\N,TSPEAR
504287,21:45955554:A>G,NM_144991.2:c.304-1748T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.232,0.0045,1KG_AFR_AF,TSPEAR
504288,21:45955561:T>C,NM_144991.2:c.304-1755A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.189,0.0014,1KG_AMR_AF,TSPEAR
504289,21:45955581:C>T,NM_144991.2:c.304-1775G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.289,\N,\N,TSPEAR
504290,21:45955583:G>A,NM_144991.2:c.304-1777C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.519,0.0014,1KG_AMR_AF,TSPEAR
504291,21:45955589:A>G,NM_144991.2:c.304-1783T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.658,0.0015,1KG_AFR_AF,TSPEAR
504292,21:45955595:G>A,NM_144991.2:c.304-1789C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.038,0.001,1KG_SAS_AF,TSPEAR
504293,21:45955600:C>G,NM_144991.2:c.304-1794G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.832,\N,\N,TSPEAR
504294,21:45955607:A>C,NM_144991.2:c.304-1801T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.287,\N,\N,TSPEAR
504295,21:45955607:A>T,NM_144991.2:c.304-1801T>A,\N,\N,2/11,Benign,\N,intron_variant,0.482,0.0204,1KG_AFR_AF,TSPEAR
504296,21:45955608:C>T,NM_144991.2:c.304-1802G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.272,\N,\N,TSPEAR
504297,21:45955657:C>CA,NM_144991.2:c.304-1852dup,\N,\N,2/11,Unknown significance,\N,intron_variant,7.584,\N,\N,TSPEAR
504298,21:45955691:C>T,NM_144991.2:c.304-1885G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.014,\N,\N,TSPEAR
504299,21:45955692:G>A,NM_144991.2:c.304-1886C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.293,\N,\N,TSPEAR
504300,21:45955695:C>T,NM_144991.2:c.304-1889G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.242,\N,\N,TSPEAR
504301,21:45955696:G>A,NM_144991.2:c.304-1890C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.164,0.0023,1KG_AFR_AF,TSPEAR
504302,21:45955701:G>A,NM_144991.2:c.304-1895C>T,\N,\N,2/11,Benign,\N,intron_variant,3.064,0.0862,1KG_AFR_AF,TSPEAR
504303,21:45955729:A>G,NM_144991.2:c.304-1923T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.375,\N,\N,TSPEAR
504304,21:45955737:G>A,NM_144991.2:c.304-1931C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,7.261,0.004,1KG_EUR_AF,TSPEAR
504305,21:45955737:G>C,NM_144991.2:c.304-1931C>G,\N,\N,2/11,Benign,\N,intron_variant,2.771,0.0106,1KG_AFR_AF,TSPEAR
504306,21:45955779:CA>C,NM_144991.2:c.304-1974del,\N,\N,2/11,Unknown significance,\N,intron_variant,5.575,\N,\N,TSPEAR
504307,21:45955779:CAA>C,NM_144991.2:c.304-1975_304-1974del,\N,\N,2/11,Unknown significance,\N,intron_variant,5.416,\N,\N,TSPEAR
504308,21:45955792:A>G,NM_144991.2:c.304-1986T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.526,\N,\N,TSPEAR
504309,21:45955792:AG>A,NM_144991.2:c.304-1987del,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
504310,21:45955792:AGG>A,NM_144991.2:c.304-1988_304-1987del,\N,\N,2/11,Unknown significance,\N,intron_variant,0.008,\N,\N,TSPEAR
504311,21:45955794:G>A,NM_144991.2:c.304-1988C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.002,\N,\N,TSPEAR
504312,21:45955796:A>G,NM_144991.2:c.304-1990T>C,\N,\N,2/11,Benign,\N,intron_variant,0.893,0.1475,1KG_AFR_AF,TSPEAR
504313,21:45955801:GA>G,NM_144991.2:c.304-1996del,\N,\N,2/11,Unknown significance,\N,intron_variant,0.076,\N,\N,TSPEAR
504314,21:45955801:GAA>G,NM_144991.2:c.304-1997_304-1996del,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
504315,21:45955822:G>A,NM_144991.2:c.304-2016C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.254,0.001,1KG_SAS_AF,TSPEAR
504316,21:45955842:A>G,NM_144991.2:c.304-2036T>C,\N,\N,2/11,Benign,\N,intron_variant,1.928,0.171,1KG_AFR_AF,TSPEAR
504317,21:45955861:T>C,NM_144991.2:c.304-2055A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.341,0.001,1KG_EAS_AF,TSPEAR
504318,21:45955879:C>A,NM_144991.2:c.304-2073G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.409,0.002,1KG_EAS_AF,TSPEAR
504319,21:45955879:C>G,NM_144991.2:c.304-2073G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.954,0.003,1KG_EAS_AF,TSPEAR
504320,21:45955975:G>A,NM_144991.2:c.304-2169C>T,\N,\N,2/11,Benign,\N,intron_variant,0.502,0.0061,1KG_SAS_AF,TSPEAR
504321,21:45956026:G>T,NM_144991.2:c.304-2220C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.61,\N,\N,TSPEAR
504322,21:45956035:G>A,NM_144991.2:c.304-2229C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.298,0.001,1KG_SAS_AF,TSPEAR
504323,21:45956057:T>TG,NM_144991.2:c.304-2252dup,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
504324,21:45956063:C>G,NM_144991.2:c.304-2257G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.987,0.0008,1KG_AFR_AF,TSPEAR
504325,21:45956080:C>T,NM_144991.2:c.304-2274G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.975,0.0008,1KG_AFR_AF,TSPEAR
504326,21:45956081:G>A,NM_144991.2:c.304-2275C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.143,0.003,1KG_AFR_AF,TSPEAR
504327,21:45956119:C>T,NM_144991.2:c.304-2313G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.599,\N,\N,TSPEAR
504328,21:45956124:C>G,NM_144991.2:c.304-2318G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.862,0.0008,1KG_AFR_AF,TSPEAR
504329,21:45956135:C>T,NM_144991.2:c.304-2329G>A,\N,\N,2/11,Benign,\N,intron_variant,0.005,0.0174,1KG_SAS_AF,TSPEAR
504330,21:45956138:C>T,NM_144991.2:c.304-2332G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.016,0.001,1KG_SAS_AF,TSPEAR
504331,21:45956146:G>A,NM_144991.2:c.304-2340C>T,\N,\N,2/11,Benign,\N,intron_variant,1.401,0.6431,1KG_SAS_AF,TSPEAR
504332,21:45956173:T>G,NM_144991.2:c.304-2367A>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.369,\N,\N,TSPEAR
504333,21:45956176:G>T,NM_144991.2:c.304-2370C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.274,\N,\N,TSPEAR
504334,21:45956194:C>T,NM_144991.2:c.304-2388G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.168,0.001,1KG_SAS_AF,TSPEAR
504335,21:45956218:T>C,NM_144991.2:c.304-2412A>G,\N,\N,2/11,Benign,\N,intron_variant,0.908,0.0076,1KG_AFR_AF,TSPEAR
504336,21:45956233:C>A,NM_144991.2:c.304-2427G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.075,0.0014,1KG_AMR_AF,TSPEAR
504337,21:45956255:G>A,NM_144991.2:c.304-2449C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.232,0.003,1KG_AFR_AF,TSPEAR
504338,21:45956291:T>C,NM_144991.2:c.304-2485A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.71,\N,\N,TSPEAR
504339,21:45956292:A>T,NM_144991.2:c.304-2486T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.173,0.0014,1KG_AMR_AF,TSPEAR
504340,21:45956408:G>A,NM_144991.2:c.304-2602C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.833,\N,\N,TSPEAR
504341,21:45956413:T>C,NM_144991.2:c.304-2607A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,4.764,0,1KG_ALL_AF|1KG_AFR_AF|1KG_AMR_AF|1KG_EAS_AF|1KG_EUR_AF|1KG_SAS_AF,TSPEAR
504342,21:45956458:C>A,NM_144991.2:c.304-2652G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.064,\N,\N,TSPEAR
504343,21:45956470:C>T,NM_144991.2:c.304-2664G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.273,0.0014,1KG_AMR_AF,TSPEAR
504344,21:45956508:C>T,NM_144991.2:c.304-2702G>A,\N,\N,2/11,Benign,\N,intron_variant,4.085,0.0245,1KG_SAS_AF,TSPEAR
504345,21:45956525:T>C,NM_144991.2:c.304-2719A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.135,0.0014,1KG_AMR_AF,TSPEAR
504346,21:45956529:T>A,NM_144991.2:c.304-2723A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.255,0.001,1KG_EUR_AF,TSPEAR
504347,21:45956544:A>G,NM_144991.2:c.304-2738T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.848,\N,\N,TSPEAR
504348,21:45956565:A>G,NM_144991.2:c.304-2759T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.809,\N,\N,TSPEAR
504349,21:45956579:A>C,NM_144991.2:c.304-2773T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.82,\N,\N,TSPEAR
504350,21:45956608:T>C,NM_144991.2:c.304-2802A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.301,0.0014,1KG_AMR_AF,TSPEAR
504351,21:45956643:A>G,NM_144991.2:c.304-2837T>C,\N,\N,2/11,Benign,\N,intron_variant,0.925,0.0092,1KG_SAS_AF,TSPEAR
504352,21:45956679:T>A,NM_144991.2:c.304-2873A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,5.798,0.003,1KG_AFR_AF,TSPEAR
504353,21:45956692:G>A,NM_144991.2:c.304-2886C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.068,0.003,1KG_AFR_AF,TSPEAR
504354,21:45956840:T>C,NM_144991.2:c.304-3034A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,12.64,0.0023,1KG_AFR_AF,TSPEAR
504355,21:45956854:T>A,NM_144991.2:c.304-3048A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,10.66,0.001,1KG_EUR_AF,TSPEAR
504356,21:45956887:T>A,NM_144991.2:c.304-3081A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,5.231,\N,\N,TSPEAR
504357,21:45956928:A>C,NM_144991.2:c.304-3122T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.028,\N,\N,TSPEAR
504358,21:45956932:A>G,NM_144991.2:c.304-3126T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.677,0.0008,1KG_AFR_AF,TSPEAR
504359,21:45956934:T>G,NM_144991.2:c.304-3128A>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.491,\N,\N,TSPEAR
504360,21:45956936:T>C,NM_144991.2:c.304-3130A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.196,\N,\N,TSPEAR
504361,21:45956959:C>G,NM_144991.2:c.304-3153G>C,\N,\N,2/11,Benign,\N,intron_variant,0.871,0.0058,1KG_AMR_AF,TSPEAR
504362,21:45956988:A>C,NM_144991.2:c.304-3182T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.057,0.0023,1KG_AFR_AF,TSPEAR
504363,21:45957001:C>T,NM_144991.2:c.304-3195G>A,\N,\N,2/11,Benign,\N,intron_variant,2.986,0.2526,1KG_SAS_AF,TSPEAR
504364,21:45957004:T>G,NM_144991.2:c.304-3198A>C,\N,\N,2/11,Benign,\N,intron_variant,3.861,0.0053,1KG_AFR_AF,TSPEAR
504365,21:45957048:A>G,NM_144991.2:c.304-3242T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.874,\N,\N,TSPEAR
504366,21:45957065:C>T,NM_144991.2:c.304-3259G>A,\N,\N,2/11,Benign,\N,intron_variant,8.223,0.1104,1KG_AFR_AF,TSPEAR
504367,21:45957066:G>A,NM_144991.2:c.304-3260C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,7.208,0.001,1KG_EAS_AF,TSPEAR
504368,21:45957082:C>CA,NM_144991.2:c.304-3277dup,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
504369,21:45957125:T>C,NM_144991.2:c.304-3319A>G,\N,\N,2/11,Benign,\N,intron_variant,2.691,0.0089,1KG_EUR_AF,TSPEAR
504370,21:45957130:GTT>G,NM_144991.2:c.304-3326_304-3325del,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
504371,21:45957157:A>G,NM_144991.2:c.304-3351T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,5.977,0.0014,1KG_AMR_AF,TSPEAR
504372,21:45957178:T>C,NM_144991.2:c.304-3372A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,5.457,\N,\N,TSPEAR
504373,21:45957181:C>T,NM_144991.2:c.304-3375G>A,\N,\N,2/11,Benign,\N,intron_variant,6.769,0.031,1KG_AFR_AF,TSPEAR
504374,21:45957198:G>T,NM_144991.2:c.304-3392C>A,\N,\N,2/11,Benign,\N,intron_variant,0.629,0.0086,1KG_AMR_AF,TSPEAR
504375,21:45957238:A>G,NM_144991.2:c.304-3432T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.179,\N,\N,TSPEAR
504376,21:45957252:T>G,NM_144991.2:c.304-3446A>C,\N,\N,2/11,Unknown significance,\N,intron_variant,3.029,0.002,1KG_SAS_AF,TSPEAR
504377,21:45957303:A>G,NM_144991.2:c.304-3497T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.117,0.0008,1KG_AFR_AF,TSPEAR
504378,21:45957352:G>A,NM_144991.2:c.304-3546C>T,\N,\N,2/11,Benign,\N,intron_variant,0.516,0.0061,1KG_SAS_AF,TSPEAR
504379,21:45957355:T>C,NM_144991.2:c.304-3549A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.458,0.0014,1KG_AMR_AF,TSPEAR
504380,21:45957360:C>T,NM_144991.2:c.304-3554G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.27,0.0015,1KG_AFR_AF,TSPEAR
504381,21:45957388:A>G,NM_144991.2:c.304-3582T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.65,\N,\N,TSPEAR
504382,21:45957397:A>G,NM_144991.2:c.304-3591T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.146,\N,\N,TSPEAR
504383,21:45957436:T>C,NM_144991.2:c.304-3630A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.124,\N,\N,TSPEAR
504384,21:45957463:G>A,NM_144991.2:c.304-3657C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.456,0.0008,1KG_AFR_AF,TSPEAR
504385,21:45957570:A>G,NM_144991.2:c.304-3764T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.029,\N,\N,TSPEAR
504386,21:45957601:C>T,NM_144991.2:c.304-3795G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.691,\N,\N,TSPEAR
504387,21:45957602:G>A,NM_144991.2:c.304-3796C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.52,\N,\N,TSPEAR
504388,21:45957607:G>A,NM_144991.2:c.304-3801C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.424,\N,\N,TSPEAR
504389,21:45957655:T>C,NM_144991.2:c.304-3849A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,2.39,\N,\N,TSPEAR
504390,21:45957755:G>A,NM_144991.2:c.304-3949C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.815,\N,\N,TSPEAR
504391,21:45957778:G>C,NM_144991.2:c.304-3972C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.311,\N,\N,TSPEAR
504392,21:45957791:C>T,NM_144991.2:c.304-3985G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.189,0.0008,1KG_AFR_AF,TSPEAR
504393,21:45957792:G>A,NM_144991.2:c.304-3986C>T,\N,\N,2/11,Benign,\N,intron_variant,0.453,0.6491,1KG_EUR_AF,TSPEAR
504394,21:45957799:C>T,NM_144991.2:c.304-3993G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.886,0.001,1KG_EAS_AF,TSPEAR
504395,21:45957800:G>A,NM_144991.2:c.304-3994C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.085,\N,\N,TSPEAR
504396,21:45957836:G>A,NM_144991.2:c.304-4030C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,4.646,\N,\N,TSPEAR
504397,21:45957846:G>A,NM_144991.2:c.304-4040C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.433,0.002,1KG_EAS_AF,TSPEAR
504398,21:45957855:C>A,NM_144991.2:c.304-4049G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.364,\N,\N,TSPEAR
504399,21:45957885:G>A,NM_144991.2:c.304-4079C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.15,\N,\N,TSPEAR
504400,21:45957895:C>T,NM_144991.2:c.304-4089G>A,\N,\N,2/11,Benign,\N,intron_variant,2.605,0.0189,1KG_AFR_AF,TSPEAR
504401,21:45957899:C>T,NM_144991.2:c.304-4093G>A,\N,\N,2/11,Benign,\N,intron_variant,4.183,0.0061,1KG_SAS_AF,TSPEAR
504402,21:45957939:T>C,NM_144991.2:c.304-4133A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.954,0.001,1KG_EUR_AF,TSPEAR
504403,21:45957952:G>C,NM_144991.2:c.304-4146C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.718,\N,\N,TSPEAR
504404,21:45957974:G>A,NM_144991.2:c.304-4168C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.318,\N,\N,TSPEAR
504405,21:45957981:C>T,NM_144991.2:c.304-4175G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.192,\N,\N,TSPEAR
504406,21:45957983:G>A,NM_144991.2:c.304-4177C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.243,\N,\N,TSPEAR
504407,21:45957984:G>C,NM_144991.2:c.304-4178C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.669,\N,\N,TSPEAR
504408,21:45957986:C>G,NM_144991.2:c.304-4180G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.776,\N,\N,TSPEAR
504409,21:45957997:G>A,NM_144991.2:c.304-4191C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.726,0.0014,1KG_AMR_AF,TSPEAR
504410,21:45957997:GTGACTGCAGCATCCCA>G,NM_144991.2:c.304-4207_304-4192del,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
504411,21:45958012:CA>C,NM_144991.2:c.304-4207del,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,0.0029,1KG_AMR_AF,TSPEAR
504412,21:45958018:C>T,NM_144991.2:c.304-4212G>A,\N,\N,2/11,Benign,\N,intron_variant,0.606,0.0068,1KG_AFR_AF,TSPEAR
504413,21:45958019:G>A,NM_144991.2:c.304-4213C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.896,0.0008,1KG_AFR_AF,TSPEAR
504414,21:45958029:A>G,NM_144991.2:c.304-4223T>C,\N,\N,2/11,Benign,\N,intron_variant,1.221,0.3303,1KG_SAS_AF,TSPEAR
504415,21:45958034:C>T,NM_144991.2:c.304-4228G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.374,0.0014,1KG_AMR_AF,TSPEAR
504416,21:45958113:C>T,NM_144991.2:c.304-4307G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.475,0.002,1KG_SAS_AF,TSPEAR
504417,21:45958114:G>A,NM_144991.2:c.304-4308C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.257,0.0015,1KG_AFR_AF,TSPEAR
504418,21:45958125:C>T,NM_144991.2:c.304-4319G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.71,0.0008,1KG_AFR_AF,TSPEAR
504419,21:45958135:T>A,NM_144991.2:c.304-4329A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,6.144,\N,\N,TSPEAR
504420,21:45958156:C>T,NM_144991.2:c.304-4350G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.761,0.0014,1KG_AMR_AF,TSPEAR
504421,21:45958158:G>A,NM_144991.2:c.304-4352C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.891,0.003,1KG_AFR_AF,TSPEAR
504422,21:45958196:C>T,NM_144991.2:c.304-4390G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.815,0.002,1KG_EUR_AF,TSPEAR
504423,21:45958197:G>A,NM_144991.2:c.304-4391C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.158,0.002,1KG_EAS_AF,TSPEAR
504424,21:45958220:T>C,NM_144991.2:c.304-4414A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.634,0.001,1KG_EAS_AF|1KG_SAS_AF,TSPEAR
504425,21:45958229:C>T,NM_144991.2:c.304-4423G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,6.022,\N,\N,TSPEAR
504426,21:45958239:G>T,NM_144991.2:c.304-4433C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.557,\N,\N,TSPEAR
504427,21:45958240:T>A,NM_144991.2:c.304-4434A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.471,\N,\N,TSPEAR
504428,21:45958244:C>T,NM_144991.2:c.304-4438G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.538,0.0045,1KG_AFR_AF,TSPEAR
504429,21:45958245:G>C,NM_144991.2:c.304-4439C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.408,0.003,1KG_AFR_AF,TSPEAR
504430,21:45958249:C>T,NM_144991.2:c.304-4443G>A,\N,\N,2/11,Benign,\N,intron_variant,1.203,0.0098,1KG_AFR_AF,TSPEAR
504431,21:45958258:C>T,NM_144991.2:c.304-4452G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.419,\N,\N,TSPEAR
504432,21:45958279:G>C,NM_144991.2:c.304-4473C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.21,0.001,1KG_EAS_AF|1KG_SAS_AF,TSPEAR
504433,21:45958281:C>A,NM_144991.2:c.304-4475G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.414,0.0014,1KG_AMR_AF,TSPEAR
504434,21:45958300:C>A,NM_144991.2:c.304-4494G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,6.689,\N,\N,TSPEAR
504435,21:45958305:GC>G,NM_144991.2:c.304-4500del,\N,\N,2/11,Unknown significance,\N,intron_variant,3.982,\N,\N,TSPEAR
504436,21:45958305:GCC>G,NM_144991.2:c.304-4501_304-4500del,\N,\N,2/11,Unknown significance,\N,intron_variant,4.918,\N,\N,TSPEAR
504437,21:45958305:GCCCCC>G,NM_144991.2:c.304-4504_304-4500del,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
504438,21:45958308:C>G,NM_144991.2:c.304-4502G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.998,\N,\N,TSPEAR
504439,21:45958309:C>A,NM_144991.2:c.304-4503G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.196,\N,\N,TSPEAR
504440,21:45958312:C>G,NM_144991.2:c.304-4506G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.037,\N,\N,TSPEAR
504441,21:45958313:C>G,NM_144991.2:c.304-4507G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.339,\N,\N,TSPEAR
504442,21:45958313:CCCCCCCA>GCC,NM_144991.2:c.304-4514_304-4507delinsGGC,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
504443,21:45958314:CCCCCCA>C,NM_144991.2:c.304-4514_304-4509del,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
504444,21:45958315:C>CCCCCA,NM_144991.2:c.304-4514_304-4510dup,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
504445,21:45958315:CCCCCA>C,NM_144991.2:c.304-4514_304-4510del,\N,\N,2/11,Unknown significance,\N,intron_variant,6.719,\N,\N,TSPEAR
504446,21:45958316:CCCCA>C,NM_144991.2:c.304-4514_304-4511del,\N,\N,2/11,Unknown significance,\N,intron_variant,7.033,\N,\N,TSPEAR
504447,21:45958316:CCCCAA>C,NM_144991.2:c.304-4515_304-4511del,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
504448,21:45958317:C>G,NM_144991.2:c.304-4511G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,3.618,\N,\N,TSPEAR
504449,21:45958318:CCA>C,NM_144991.2:c.304-4514_304-4513del,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
504450,21:45958319:CA>C,NM_144991.2:c.304-4514del,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
504451,21:45958340:G>A,NM_144991.2:c.304-4534C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.76,0.0015,1KG_AFR_AF,TSPEAR
504452,21:45958354:G>A,NM_144991.2:c.304-4548C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.549,0.0008,1KG_AFR_AF,TSPEAR
504453,21:45958366:T>A,NM_144991.2:c.304-4560A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.794,0.001,1KG_EUR_AF,TSPEAR
504454,21:45958367:C>T,NM_144991.2:c.304-4561G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.731,0.001,1KG_EUR_AF,TSPEAR
504455,21:45958401:C>T,NM_144991.2:c.304-4595G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.849,\N,\N,TSPEAR
504456,21:45958419:C>T,NM_144991.2:c.304-4613G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.04,0.0029,1KG_AMR_AF,TSPEAR
504457,21:45958432:GCC>G,NM_144991.2:c.304-4628_304-4627del,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
504458,21:45958439:C>T,NM_144991.2:c.304-4633G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.433,0.0029,1KG_AMR_AF,TSPEAR
504459,21:45958449:C>T,NM_144991.2:c.304-4643G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.661,\N,\N,TSPEAR
504460,21:45958455:G>A,NM_144991.2:c.304-4649C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.708,0.001,1KG_SAS_AF,TSPEAR
504461,21:45958460:TA>T,NM_144991.2:c.304-4655del,\N,\N,2/11,Benign,\N,intron_variant,4.151,0.3466,1KG_SAS_AF,TSPEAR
504462,21:45958487:G>A,NM_144991.2:c.304-4681C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.116,0.002,1KG_SAS_AF,TSPEAR
504463,21:45958500:G>C,NM_144991.2:c.304-4694C>G,\N,\N,2/11,Benign,\N,intron_variant,2.222,0.3456,1KG_SAS_AF,TSPEAR
504464,21:45958500:G>T,NM_144991.2:c.304-4694C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.343,\N,\N,TSPEAR
504465,21:45958502:T>A,NM_144991.2:c.304-4696A>T,\N,\N,2/11,Benign,\N,intron_variant,8.799,0.0741,1KG_AFR_AF,TSPEAR
504466,21:45958512:T>G,NM_144991.2:c.304-4706A>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.747,0.0023,1KG_AFR_AF,TSPEAR
504467,21:45958521:C>T,NM_144991.2:c.304-4715G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.684,0.0014,1KG_AMR_AF,TSPEAR
504468,21:45958532:C>A,NM_144991.2:c.304-4726G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.935,0.004,1KG_EAS_AF,TSPEAR
504469,21:45958548:C>T,NM_144991.2:c.304-4742G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.171,0.0008,1KG_AFR_AF,TSPEAR
504470,21:45958549:G>A,NM_144991.2:c.304-4743C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.042,\N,\N,TSPEAR
504471,21:45958552:A>G,NM_144991.2:c.304-4746T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.703,0.0045,1KG_AFR_AF,TSPEAR
504472,21:45958553:G>A,NM_144991.2:c.304-4747C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.474,0.001,1KG_EUR_AF,TSPEAR
504473,21:45958566:T>G,NM_144991.2:c.304-4760A>C,\N,\N,2/11,Benign,\N,intron_variant,2.588,0.0286,1KG_SAS_AF,TSPEAR
504474,21:45958583:G>A,NM_144991.2:c.304-4777C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.858,0.001,1KG_EAS_AF,TSPEAR
504475,21:45958585:G>A,NM_144991.2:c.304-4779C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.847,\N,\N,TSPEAR
504476,21:45958604:C>T,NM_144991.2:c.304-4798G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.221,0.001,1KG_SAS_AF,TSPEAR
504477,21:45958619:C>T,NM_144991.2:c.304-4813G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,5.388,0.003,1KG_EUR_AF,TSPEAR
504478,21:45958667:G>A,NM_144991.2:c.304-4861C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.862,\N,\N,TSPEAR
504479,21:45958676:G>T,NM_144991.2:c.304-4870C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.516,\N,\N,TSPEAR
504480,21:45958683:C>T,NM_144991.2:c.304-4877G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.815,0.002,1KG_EAS_AF,TSPEAR
504481,21:45958701:G>A,NM_144991.2:c.304-4895C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.803,0.0008,1KG_AFR_AF,TSPEAR
504482,21:45958738:G>A,NM_144991.2:c.304-4932C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.114,\N,\N,TSPEAR
504483,21:45958803:TGGA>T,NM_144991.2:c.304-5000_304-4998del,\N,\N,2/11,Benign,\N,intron_variant,5.605,0.0179,1KG_EAS_AF,TSPEAR
504484,21:45958804:G>A,NM_144991.2:c.304-4998C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,4.854,0.0014,1KG_AMR_AF,TSPEAR
504485,21:45958806:A>G,NM_144991.2:c.304-5000T>C,\N,\N,2/11,Benign,\N,intron_variant,4.75,0.0072,1KG_AMR_AF,TSPEAR
504486,21:45958869:T>C,NM_144991.2:c.304-5063A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,5.44,\N,\N,TSPEAR
504487,21:45958878:A>G,NM_144991.2:c.304-5072T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.989,\N,\N,TSPEAR
504488,21:45958886:T>C,NM_144991.2:c.304-5080A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,10.47,0.001,1KG_EAS_AF,TSPEAR
504489,21:45958910:G>C,NM_144991.2:c.304-5104C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.285,0.0031,1KG_SAS_AF,TSPEAR
504490,21:45958921:C>T,NM_144991.2:c.304-5115G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.448,0.0008,1KG_AFR_AF,TSPEAR
504491,21:45958922:G>A,NM_144991.2:c.304-5116C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.624,\N,\N,TSPEAR
504492,21:45958931:T>C,NM_144991.2:c.304-5125A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,4.259,0.0008,1KG_AFR_AF,TSPEAR
504493,21:45958962:CA>C,NM_144991.2:c.304-5157del,\N,\N,2/11,Unknown significance,\N,intron_variant,7.692,\N,\N,TSPEAR
504494,21:45958970:C>CT,NM_144991.2:c.304-5165dup,\N,\N,2/11,Unknown significance,\N,intron_variant,6.748,\N,\N,TSPEAR
504495,21:45958971:T>C,NM_144991.2:c.304-5165A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,2.137,0.0014,1KG_AMR_AF,TSPEAR
504496,21:45958994:G>A,NM_144991.2:c.304-5188C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.971,0.0023,1KG_AFR_AF,TSPEAR
504497,21:45959030:T>A,NM_144991.2:c.304-5224A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,6.002,0.0008,1KG_AFR_AF,TSPEAR
504498,21:45959043:GA>G,NM_144991.2:c.304-5238del,\N,\N,2/11,Unknown significance,\N,intron_variant,0.455,\N,\N,TSPEAR
504499,21:45959044:A>AG,NM_144991.2:c.304-5239dup,\N,\N,2/11,Unknown significance,\N,intron_variant,3.398,0.0023,1KG_AFR_AF,TSPEAR
504500,21:45959046:G>C,NM_144991.2:c.304-5240C>G,\N,\N,2/11,Benign,\N,intron_variant,1.923,0.0102,1KG_SAS_AF,TSPEAR
504501,21:45959050:G>A,NM_144991.2:c.304-5244C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,6.747,\N,\N,TSPEAR
504502,21:45959074:C>T,NM_198691.2:c.*111G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,2.542,\N,\N,TSPEAR
504503,21:45959079:A>AC,NM_198691.2:c.*105dup,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,\N,\N,\N,TSPEAR
504504,21:45959083:G>A,NM_198691.2:c.*102C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,0.209,0.001,1KG_EAS_AF,TSPEAR
504505,21:45959087:T>C,NM_198691.2:c.*98A>G,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,0.698,\N,\N,TSPEAR
504506,21:45959092:G>A,NM_198691.2:c.*93C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,0.631,\N,\N,TSPEAR
504507,21:45959094:G>A,NM_198691.2:c.*91C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,6.356,0.0008,1KG_AFR_AF,TSPEAR
504508,21:45959097:A>C,NM_198691.2:c.*88T>G,\N,1/1,\N,Benign,\N,3_prime_UTR_variant,1.762,0.7095,1KG_AFR_AF,TSPEAR
504509,21:45959104:C>T,NM_198691.2:c.*81G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,2.919,\N,\N,TSPEAR
504510,21:45959108:C>T,NM_198691.2:c.*77G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,3.926,0.001,1KG_EUR_AF,TSPEAR
504511,21:45959109:C>G,NM_198691.2:c.*76G>C,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,1.819,0.0000197699,EXAC_NFE_AF,TSPEAR
504512,21:45959118:G>A,NM_198691.2:c.*67C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,6.065,\N,\N,TSPEAR
504513,21:45959121:C>T,NM_198691.2:c.*64G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,3,0.000212224,EXAC_FIN_AF,TSPEAR
504514,21:45959123:G>C,NM_198691.2:c.*62C>G,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,1.5,0.000143431,EXAC_AFR_AF,TSPEAR
504515,21:45959131:C>T,NM_198691.2:c.*54G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,6.299,0.000143678,EXAC_EAS_AF,TSPEAR
504516,21:45959142:C>T,NM_198691.2:c.*43G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,5.516,0.0000183399,EXAC_NFE_AF,TSPEAR
504517,21:45959143:G>A,NM_198691.2:c.*42C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,1.215,0.000983671,EXAC_AMR_AF,TSPEAR
504518,21:45959143:G>C,NM_198691.2:c.*42C>G,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,0.239,0.001,1KG_EAS_AF,TSPEAR
504519,21:45959145:G>A,NM_198691.2:c.*40C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,1.156,0.0000179488,EXAC_NFE_AF,TSPEAR
504520,21:45959148:C>T,NM_198691.2:c.*37G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,6.609,0.0000965437,EXAC_SAS_AF,TSPEAR
504521,21:45959149:C>A,NM_198691.2:c.*36G>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,0.867,0.00038219,EXAC_SAS_AF,TSPEAR
504522,21:45959158:G>A,NM_198691.2:c.*27C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,10.74,0.000180865,EXAC_SAS_AF,TSPEAR
504523,21:45959161:G>A,NM_198691.2:c.*24C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,5.404,0.000017207,EXAC_NFE_AF,TSPEAR
504524,21:45959165:T>A,NM_198691.2:c.*20A>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,5.249,\N,\N,TSPEAR
504525,21:45959166:C>T,NM_198691.2:c.*19G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,2.621,0.000662612,EXAC_NFE_AF,TSPEAR
504526,21:45959169:G>T,NM_198691.2:c.*16C>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,4.485,0.00020273,EXAC_NFE_AF,TSPEAR
504527,21:45959170:G>T,NM_198691.2:c.*15C>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,0.723,0.0000337348,EXAC_NFE_AF,TSPEAR
504528,21:45959177:C>G,NM_198691.2:c.*8G>C,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,0.417,0.000120482,EXAC_AFR_AF,TSPEAR
504529,21:45959181:G>A,NM_198691.2:c.*4C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,3.981,0.0000900739,EXAC_AMR_AF,TSPEAR
504530,21:45959183:C>T,NM_198691.2:c.*2G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,0.471,0.000834725,EXAC_AFR_AF,TSPEAR
504531,21:45959184:C>T,NM_198691.2:c.*1G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,1.726,0.000297255,EXAC_NFE_AF,TSPEAR
504532,21:45959185:T>G,NM_198691.2:c.849A>C,NP_941964.2:p.Ter283CysextTer11,1/1,\N,Unknown significance,\N,stop_lost,0.72,0.000296951,EXAC_NFE_AF,TSPEAR
504533,21:45959186:C>T,NM_198691.2:c.848G>A,NP_941964.2:p.Ter283=,1/1,\N,Unknown significance,\N,stop_retained_variant,8.061,0.000296452,EXAC_NFE_AF,TSPEAR
504534,21:45959188:G>C,NM_198691.2:c.846C>G,NP_941964.2:p.Cys282Trp,1/1,\N,Unknown significance,\N,missense_variant,22.8,0.0000895415,EXAC_AMR_AF,TSPEAR
504535,21:45959189:C>G,NM_198691.2:c.845G>C,NP_941964.2:p.Cys282Ser,1/1,\N,Unknown significance,\N,missense_variant,20.3,0.0000164193,EXAC_NFE_AF,TSPEAR
504536,21:45959191:G>A,NM_198691.2:c.843C>T,NP_941964.2:p.Ala281=,1/1,\N,Unknown significance,\N,synonymous_variant,3.448,0.0000711642,EXAC_SAS_AF,TSPEAR
504537,21:45959191:G>T,NM_198691.2:c.843C>A,NP_941964.2:p.Ala281=,1/1,\N,Unknown significance,\N,synonymous_variant,0.952,0.0000163425,EXAC_NFE_AF,TSPEAR
504538,21:45959192:G>T,NM_198691.2:c.842C>A,NP_941964.2:p.Ala281Asp,1/1,\N,Unknown significance,\N,missense_variant,21.8,0.00120602,EXAC_SAS_AF,TSPEAR
504539,21:45959194:C>A,NM_198691.2:c.840G>T,NP_941964.2:p.Pro280=,1/1,\N,Unknown significance,\N,synonymous_variant,9.113,0.000489784,EXAC_SAS_AF,TSPEAR
504540,21:45959195:G>A,NM_198691.2:c.839C>T,NP_941964.2:p.Pro280Leu,1/1,\N,Benign,\N,missense_variant,8.438,0.7519,1KG_AFR_AF,TSPEAR
504541,21:45959197:G>A,NM_198691.2:c.837C>T,NP_941964.2:p.Arg279=,1/1,\N,Unknown significance,\N,synonymous_variant,0.808,0.0045,1KG_AFR_AF,TSPEAR
504542,21:45959198:C>G,NM_198691.2:c.836G>C,NP_941964.2:p.Arg279Pro,1/1,\N,Unknown significance,\N,missense_variant,22.2,\N,\N,TSPEAR
504543,21:45959199:G>A,NM_198691.2:c.835C>T,NP_941964.2:p.Arg279Cys,1/1,\N,Unknown significance,\N,missense_variant,22.3,0.000124533,EXAC_SAS_AF,TSPEAR
504544,21:45959205:A>T,NM_198691.2:c.829T>A,NP_941964.2:p.Cys277Ser,1/1,\N,Unknown significance,\N,missense_variant,11.99,\N,\N,TSPEAR
504545,21:45959206:C>A,NM_198691.2:c.828G>T,NP_941964.2:p.Ala276=,1/1,\N,Unknown significance,\N,synonymous_variant,13.12,0.000119076,EXAC_EAS_AF,TSPEAR
504546,21:45959206:C>T,NM_198691.2:c.828G>A,NP_941964.2:p.Ala276=,1/1,\N,Unknown significance,\N,synonymous_variant,11.53,0.000218914,EXAC_AFR_AF,TSPEAR
504547,21:45959207:G>A,NM_198691.2:c.827C>T,NP_941964.2:p.Ala276Val,1/1,\N,Likely benign,\N,missense_variant,0.029,0.0011655,EXAC_OTH_AF,TSPEAR
504548,21:45959208:C>T,NM_198691.2:c.826G>A,NP_941964.2:p.Ala276Thr,1/1,\N,Likely benign,\N,missense_variant,1.206,0.000123655,EXAC_SAS_AF,TSPEAR
504549,21:45959209:G>A,NM_198691.2:c.825C>T,NP_941964.2:p.Pro275=,1/1,\N,Unknown significance,\N,synonymous_variant,2.126,0.001,1KG_EAS_AF,TSPEAR
504550,21:45959210:G>A,NM_198691.2:c.824C>T,NP_941964.2:p.Pro275Leu,1/1,\N,Unknown significance,\N,missense_variant,15.74,0.0000155502,EXAC_NFE_AF,TSPEAR
504551,21:45959213:C>T,NM_198691.2:c.821G>A,NP_941964.2:p.Arg274His,1/1,\N,Likely benign,\N,missense_variant,13.33,0.000228311,EVS_AA_AF,TSPEAR
504552,21:45959214:G>A,NM_198691.2:c.820C>T,NP_941964.2:p.Arg274Cys,1/1,\N,Unknown significance,\N,missense_variant,22.9,0.000594672,EXAC_EAS_AF,TSPEAR
504553,21:45959214:G>C,NM_198691.2:c.820C>G,NP_941964.2:p.Arg274Gly,1/1,\N,Unknown significance,\N,missense_variant,20.1,0.00142721,EXAC_EAS_AF,TSPEAR
504554,21:45959220:G>A,NM_198691.2:c.814C>T,NP_941964.2:p.Leu272Phe,1/1,\N,Likely benign,\N,missense_variant,13.74,0.0000875657,EXAC_AMR_AF,TSPEAR
504555,21:45959227:C>A,NM_198691.2:c.807G>T,NP_941964.2:p.Val269=,1/1,\N,Unknown significance,\N,synonymous_variant,7.948,\N,\N,TSPEAR
504556,21:45959227:C>T,NM_198691.2:c.807G>A,NP_941964.2:p.Val269=,1/1,\N,Unknown significance,\N,synonymous_variant,6.789,\N,\N,TSPEAR
504557,21:45959229:C>T,NM_198691.2:c.805G>A,NP_941964.2:p.Val269Met,1/1,\N,Likely benign,\N,missense_variant,1.824,0.000350324,EXAC_AMR_AF,TSPEAR
504558,21:45959230:G>A,NM_198691.2:c.804C>T,NP_941964.2:p.Cys268=,1/1,\N,Unknown significance,\N,synonymous_variant,0.937,0.0000154383,EXAC_NFE_AF,TSPEAR
504559,21:45959236:G>T,NM_198691.2:c.798C>A,NP_941964.2:p.Ala266=,1/1,\N,Unknown significance,\N,synonymous_variant,0.149,0.0008,1KG_AFR_AF,TSPEAR
504560,21:45959239:C>T,NM_198691.2:c.795G>A,NP_941964.2:p.Pro265=,1/1,\N,Benign,\N,synonymous_variant,9.736,0.006,1KG_EAS_AF,TSPEAR
504561,21:45959240:G>A,NM_198691.2:c.794C>T,NP_941964.2:p.Pro265Leu,1/1,\N,Unknown significance,\N,missense_variant,17.2,0.0000874126,EXAC_AMR_AF,TSPEAR
504562,21:45959240:G>T,NM_198691.2:c.794C>A,NP_941964.2:p.Pro265Gln,1/1,\N,Likely benign,\N,missense_variant,7.897,0.000118371,EXAC_EAS_AF,TSPEAR
504563,21:45959241:G>T,NM_198691.2:c.793C>A,NP_941964.2:p.Pro265Thr,1/1,\N,Unknown significance,\N,missense_variant,1.519,0.000236574,EXAC_EAS_AF,TSPEAR
504564,21:45959243:C>T,NM_198691.2:c.791G>A,NP_941964.2:p.Arg264His,1/1,\N,Likely benign,\N,missense_variant,12.24,0.000227376,EVS_AA_AF,TSPEAR
504565,21:45959244:G>A,NM_198691.2:c.790C>T,NP_941964.2:p.Arg264Cys,1/1,\N,Likely benign,\N,missense_variant,11.67,0.0000153398,EXAC_NFE_AF,TSPEAR
504566,21:45959244:G>T,NM_198691.2:c.790C>A,NP_941964.2:p.Arg264Ser,1/1,\N,Likely benign,\N,missense_variant,8.945,0.0000306796,EXAC_NFE_AF,TSPEAR
504567,21:45959248:G>A,NM_198691.2:c.786C>T,NP_941964.2:p.Cys262=,1/1,\N,Unknown significance,\N,synonymous_variant,0.107,0.0000608051,EXAC_SAS_AF,TSPEAR
504568,21:45959249:C>T,NM_198691.2:c.785G>A,NP_941964.2:p.Cys262Tyr,1/1,\N,Unknown significance,\N,missense_variant,17.32,0.0000607903,EXAC_SAS_AF,TSPEAR
504569,21:45959251:G>A,NM_198691.2:c.783C>T,NP_941964.2:p.Ser261=,1/1,\N,Unknown significance,\N,synonymous_variant,0.664,0.00008726,EXAC_AMR_AF,TSPEAR
504570,21:45959256:C>A,NM_198691.2:c.778G>T,NP_941964.2:p.Ala260Ser,1/1,\N,Likely benign,\N,missense_variant,0.301,0.0031,1KG_SAS_AF,TSPEAR
504571,21:45959256:C>G,NM_198691.2:c.778G>C,NP_941964.2:p.Ala260Pro,1/1,\N,Benign,\N,missense_variant,0.001,0.0189,1KG_EUR_AF,TSPEAR
504572,21:45959260:G>T,NM_198691.2:c.774C>A,NP_941964.2:p.Cys258Ter,1/1,\N,Unknown significance,\N,stop_gained,35,0.000104756,EXAC_AFR_AF,TSPEAR
504573,21:45959261:C>A,NM_198691.2:c.773G>T,NP_941964.2:p.Cys258Phe,1/1,\N,Unknown significance,\N,missense_variant,17.37,0.000152858,EXAC_FIN_AF,TSPEAR
504574,21:45959261:C>T,NM_198691.2:c.773G>A,NP_941964.2:p.Cys258Tyr,1/1,\N,Unknown significance,\N,missense_variant,14.69,0.0045,1KG_AFR_AF,TSPEAR
504575,21:45959262:A>G,NM_198691.2:c.772T>C,NP_941964.2:p.Cys258Arg,1/1,\N,Unknown significance,\N,missense_variant,16.77,0.000348675,EXAC_AMR_AF,TSPEAR
504576,21:45959265:A>T,NM_198691.2:c.769T>A,NP_941964.2:p.Ser257Thr,1/1,\N,Unknown significance,\N,missense_variant,16.27,0.0000151985,EXAC_NFE_AF,TSPEAR
504577,21:45959267:G>A,NM_198691.2:c.767C>T,NP_941964.2:p.Ser256Phe,1/1,\N,Unknown significance,\N,missense_variant,16.29,0.0000151865,EXAC_NFE_AF,TSPEAR
504578,21:45959268:AGG>A,NM_198691.2:c.764_765del,NP_941964.2:p.Ala255ValfsTer52,1/1,\N,Unknown significance,\N,frameshift_variant,24,\N,\N,TSPEAR
504579,21:45959271:C>T,NM_198691.2:c.763G>A,NP_941964.2:p.Ala255Thr,1/1,\N,Likely benign,\N,missense_variant,0.001,0.002,1KG_EAS_AF,TSPEAR
504580,21:45959272:A>ACG,NM_198691.2:c.761_762insCG,NP_941964.2:p.Ala255ValfsTer?,1/1,\N,Unknown significance,\N,frameshift_variant,23.4,0.00123686,EXAC_AFR_AF,TSPEAR
504581,21:45959272:A>G,NM_198691.2:c.762T>C,NP_941964.2:p.Pro254=,1/1,\N,Unknown significance,\N,synonymous_variant,0.016,0.003,1KG_EAS_AF,TSPEAR
504582,21:45959274:G>A,NM_198691.2:c.760C>T,NP_941964.2:p.Pro254Ser,1/1,\N,Likely benign,\N,missense_variant,1.174,\N,\N,TSPEAR
504583,21:45959276:G>A,NM_198691.2:c.758C>T,NP_941964.2:p.Ala253Val,1/1,\N,Benign,\N,missense_variant,3.349,0.0111484,EXAC_FIN_AF,TSPEAR
504584,21:45959276:G>T,NM_198691.2:c.758C>A,NP_941964.2:p.Ala253Asp,1/1,\N,Likely benign,\N,missense_variant,12.47,0.0000151419,EXAC_NFE_AF,TSPEAR
504585,21:45959278:A>G,NM_198691.2:c.756T>C,NP_941964.2:p.Cys252=,1/1,\N,Unknown significance,\N,synonymous_variant,0.004,0.0000151309,EXAC_NFE_AF,TSPEAR
504586,21:45959279:C>T,NM_198691.2:c.755G>A,NP_941964.2:p.Cys252Tyr,1/1,\N,Benign,\N,missense_variant,11.25,0.0356,1KG_AFR_AF,TSPEAR
504587,21:45959280:A>G,NM_198691.2:c.754T>C,NP_941964.2:p.Cys252Arg,1/1,\N,Benign,\N,missense_variant,11.49,0.0179,1KG_EAS_AF,TSPEAR
504588,21:45959281:G>A,NM_198691.2:c.753C>T,NP_941964.2:p.Cys251=,1/1,\N,Benign,\N,synonymous_variant,0.095,0.0111382,EXAC_FIN_AF,TSPEAR
504589,21:45959282:C>T,NM_198691.2:c.752G>A,NP_941964.2:p.Cys251Tyr,1/1,\N,Unknown significance,\N,missense_variant,17.78,\N,\N,TSPEAR
504590,21:45959289:A>G,NM_198691.2:c.745T>C,NP_941964.2:p.Ser249Pro,1/1,\N,Likely benign,\N,missense_variant,0.075,0.0045217,EXAC_AFR_AF,TSPEAR
504591,21:45959291:A>G,NM_198691.2:c.743T>C,NP_941964.2:p.Val248Ala,1/1,\N,Likely benign,\N,missense_variant,0.009,0.000015082,EXAC_NFE_AF,TSPEAR
504592,21:45959291:A>T,NM_198691.2:c.743T>A,NP_941964.2:p.Val248Asp,1/1,\N,Likely benign,\N,missense_variant,0.658,0.000182083,EXAC_SAS_AF,TSPEAR
504593,21:45959292:C>G,NM_198691.2:c.742G>C,NP_941964.2:p.Val248Leu,1/1,\N,Likely benign,\N,missense_variant,0.011,0.000015078,EXAC_NFE_AF,TSPEAR
504594,21:45959292:C>T,NM_198691.2:c.742G>A,NP_941964.2:p.Val248Ile,1/1,\N,Likely benign,\N,missense_variant,0.005,0.00481831,EXAC_AFR_AF,TSPEAR
504595,21:45959292:CA>TG,NM_198691.2:c.741_742inv,NP_941964.2:p.Val248Ile,1/1,\N,Unknown significance,\N,missense_variant,\N,\N,\N,TSPEAR
504596,21:45959293:A>AGGCATACAGCAGGCGGGCC,NM_198691.2:c.722_740dup,NP_941964.2:p.Val248AlafsTer66,1/1,\N,Unknown significance,\N,frameshift_variant,22.9,0.0000150743,EXAC_NFE_AF,TSPEAR
504597,21:45959293:A>G,NM_198691.2:c.741T>C,NP_941964.2:p.Pro247=,1/1,\N,Benign,\N,synonymous_variant,0.003,0.0188128,EXAC_EAS_AF,TSPEAR
504598,21:45959298:T>C,NM_198691.2:c.736A>G,NP_941964.2:p.Met246Val,1/1,\N,Benign,\N,missense_variant,0.001,0.0198,1KG_EAS_AF,TSPEAR
504599,21:45959299:A>G,NM_198691.2:c.735T>C,NP_941964.2:p.Cys245=,1/1,\N,Unknown significance,\N,synonymous_variant,0.002,0.00378561,EXAC_AFR_AF,TSPEAR
504600,21:45959306:G>T,NM_198691.2:c.728C>A,NP_941964.2:p.Ala243Asp,1/1,\N,Unknown significance,\N,missense_variant,17.81,0.0000150485,EXAC_NFE_AF,TSPEAR
504601,21:45959307:C>A,NM_198691.2:c.727G>T,NP_941964.2:p.Ala243Ser,1/1,\N,Unknown significance,\N,missense_variant,7.595,0.0014,1KG_AMR_AF,TSPEAR
504602,21:45959307:C>T,NM_198691.2:c.727G>A,NP_941964.2:p.Ala243Thr,1/1,\N,Unknown significance,\N,missense_variant,7.529,0.000667314,EXAC_SAS_AF,TSPEAR
504603,21:45959308:G>A,NM_198691.2:c.726C>T,NP_941964.2:p.Pro242=,1/1,\N,Benign,\N,synonymous_variant,1.837,0.0216703,EXAC_AFR_AF,TSPEAR
504604,21:45959310:G>A,NM_198691.2:c.724C>T,NP_941964.2:p.Pro242Ser,1/1,\N,Unknown significance,\N,missense_variant,0.048,\N,\N,TSPEAR
504605,21:45959311:C>A,NM_198691.2:c.723G>T,NP_941964.2:p.Arg241=,1/1,\N,Unknown significance,\N,synonymous_variant,5.767,0.0000150412,EXAC_NFE_AF,TSPEAR
504606,21:45959311:C>T,NM_198691.2:c.723G>A,NP_941964.2:p.Arg241=,1/1,\N,Unknown significance,\N,synonymous_variant,4.861,0.0000150412,EXAC_NFE_AF,TSPEAR
504607,21:45959312:C>T,NM_198691.2:c.722G>A,NP_941964.2:p.Arg241Gln,1/1,\N,Benign,\N,missense_variant,17.64,0.8906,1KG_SAS_AF,TSPEAR
504608,21:45959313:G>A,NM_198691.2:c.721C>T,NP_941964.2:p.Arg241Trp,1/1,\N,Unknown significance,\N,missense_variant,22.4,0.0000865501,EXAC_AMR_AF,TSPEAR
504609,21:45959313:G>T,NM_198691.2:c.721C>A,NP_941964.2:p.Arg241=,1/1,\N,Unknown significance,\N,synonymous_variant,2.911,0.0029,1KG_AMR_AF,TSPEAR
504610,21:45959317:T>C,NM_198691.2:c.717A>G,NP_941964.2:p.Val239=,1/1,\N,Benign,\N,synonymous_variant,0.007,0.0401,1KG_AFR_AF,TSPEAR
504611,21:45959319:C>T,NM_198691.2:c.715G>A,NP_941964.2:p.Val239Ile,1/1,\N,Unknown significance,\N,missense_variant,6.461,0.0029,1KG_AMR_AF,TSPEAR
504612,21:45959320:A>G,NM_198691.2:c.714T>C,NP_941964.2:p.Pro238=,1/1,\N,Unknown significance,\N,synonymous_variant,0.002,0.0029,1KG_AMR_AF,TSPEAR
504613,21:45959322:G>A,NM_198691.2:c.712C>T,NP_941964.2:p.Pro238Ser,1/1,\N,Unknown significance,\N,missense_variant,17.29,0.0000149957,EXAC_NFE_AF,TSPEAR
504614,21:45959324:C>T,NM_198691.2:c.710G>A,NP_941964.2:p.Arg237His,1/1,\N,Unknown significance,\N,missense_variant,20.1,0.000116063,EXAC_EAS_AF,TSPEAR
504615,21:45959325:G>A,NM_198691.2:c.709C>T,NP_941964.2:p.Arg237Cys,1/1,\N,Unknown significance,\N,missense_variant,24.1,0.000227066,EVS_AA_AF,TSPEAR
504616,21:45959330:A>G,NM_198691.2:c.704T>C,NP_941964.2:p.Leu235Pro,1/1,\N,Unknown significance,\N,missense_variant,16.99,0.0000299868,EXAC_NFE_AF,TSPEAR
504617,21:45959332:G>T,NM_198691.2:c.702C>A,NP_941964.2:p.Leu234=,1/1,\N,Unknown significance,\N,synonymous_variant,3.729,0.0000605767,EXAC_SAS_AF,TSPEAR
504618,21:45959340:C>A,NM_198691.2:c.694G>T,NP_941964.2:p.Val232Leu,1/1,\N,Unknown significance,\N,missense_variant,17.38,0.0000149948,EXAC_NFE_AF,TSPEAR
504619,21:45959340:C>T,NM_198691.2:c.694G>A,NP_941964.2:p.Val232Met,1/1,\N,Unknown significance,\N,missense_variant,16.2,0.002,1KG_EAS_AF,TSPEAR
504620,21:45959340:CGGA>C,NM_198691.2:c.691_693del,NP_941964.2:p.Ser231del,1/1,\N,Benign,\N,inframe_deletion,6.986,0.1029,1KG_AFR_AF,TSPEAR
504621,21:45959341:G>A,NM_198691.2:c.693C>T,NP_941964.2:p.Ser231=,1/1,\N,Unknown significance,\N,synonymous_variant,9.551,0.000074994,EXAC_NFE_AF,TSPEAR
504622,21:45959341:G>T,NM_198691.2:c.693C>A,NP_941964.2:p.Ser231=,1/1,\N,Unknown significance,\N,synonymous_variant,4.398,0.0000149988,EXAC_NFE_AF,TSPEAR
504623,21:45959348:G>C,NM_198691.2:c.686C>G,NP_941964.2:p.Ser229Cys,1/1,\N,Unknown significance,\N,missense_variant,11.05,0.000242277,EXAC_SAS_AF,TSPEAR
504624,21:45959357:C>T,NM_198691.2:c.677G>A,NP_941964.2:p.Cys226Tyr,1/1,\N,Unknown significance,\N,missense_variant,23.1,0.000226963,EVS_AA_AF,TSPEAR
504625,21:45959360:C>T,NM_198691.2:c.674G>A,NP_941964.2:p.Cys225Tyr,1/1,\N,Unknown significance,\N,missense_variant,22.7,0.0000149925,EXAC_NFE_AF,TSPEAR
504626,21:45959361:A>G,NM_198691.2:c.673T>C,NP_941964.2:p.Cys225Arg,1/1,\N,Unknown significance,\N,missense_variant,21.8,\N,\N,TSPEAR
504627,21:45959367:T>A,NM_198691.2:c.667A>T,NP_941964.2:p.Thr223Ser,1/1,\N,Unknown significance,\N,missense_variant,0.001,0.0000864304,EXAC_AMR_AF,TSPEAR
504628,21:45959367:T>C,NM_198691.2:c.667A>G,NP_941964.2:p.Thr223Ala,1/1,\N,Unknown significance,\N,missense_variant,0.021,0.0000149925,EXAC_NFE_AF,TSPEAR
504629,21:45959371:G>A,NM_198691.2:c.663C>T,NP_941964.2:p.Cys221=,1/1,\N,Unknown significance,\N,synonymous_variant,0.023,\N,\N,TSPEAR
504630,21:45959373:A>G,NM_198691.2:c.661T>C,NP_941964.2:p.Cys221Arg,1/1,\N,Unknown significance,\N,missense_variant,14.71,\N,\N,TSPEAR
504631,21:45959380:C>T,NM_198691.2:c.654G>A,NP_941964.2:p.Pro218=,1/1,\N,Unknown significance,\N,synonymous_variant,8.683,0.002,1KG_SAS_AF,TSPEAR
504632,21:45959381:G>A,NM_198691.2:c.653C>T,NP_941964.2:p.Pro218Leu,1/1,\N,Unknown significance,\N,missense_variant,22.4,0.0008,1KG_AFR_AF,TSPEAR
504633,21:45959381:G>T,NM_198691.2:c.653C>A,NP_941964.2:p.Pro218Gln,1/1,\N,Unknown significance,\N,missense_variant,20.7,\N,\N,TSPEAR
504634,21:45959386:G>A,NM_198691.2:c.648C>T,NP_941964.2:p.Cys216=,1/1,\N,Benign,\N,synonymous_variant,0.12,0.671,1KG_AFR_AF,TSPEAR
504635,21:45959387:C>T,NM_198691.2:c.647G>A,NP_941964.2:p.Cys216Tyr,1/1,\N,Unknown significance,\N,missense_variant,19.34,\N,\N,TSPEAR
504636,21:45959387:CA>C,NM_198691.2:c.646del,NP_941964.2:p.Cys216AlafsTer?,1/1,\N,Unknown significance,\N,frameshift_variant,25.8,\N,\N,TSPEAR
504637,21:45959388:A>G,NM_198691.2:c.646T>C,NP_941964.2:p.Cys216Arg,1/1,\N,Unknown significance,\N,missense_variant,17.8,0.0015,1KG_AFR_AF,TSPEAR
504638,21:45959390:C>T,NM_198691.2:c.644G>A,NP_941964.2:p.Ser215Asn,1/1,\N,Unknown significance,\N,missense_variant,9.006,0.000116333,EVS_EA_AF,TSPEAR
504639,21:45959391:T>C,NM_198691.2:c.643A>G,NP_941964.2:p.Ser215Gly,1/1,\N,Unknown significance,\N,missense_variant,0.055,0.001047,EVS_EA_AF,TSPEAR
504640,21:45959394:A>G,NM_198691.2:c.640T>C,NP_941964.2:p.Ser214Pro,1/1,\N,Unknown significance,\N,missense_variant,11.99,\N,\N,TSPEAR
504641,21:45959398:C>T,NM_198691.2:c.636G>A,NP_941964.2:p.Gln212=,1/1,\N,Unknown significance,\N,synonymous_variant,1.179,0.000121124,EXAC_SAS_AF,TSPEAR
504642,21:45959401:G>A,NM_198691.2:c.633C>T,NP_941964.2:p.Cys211=,1/1,\N,Unknown significance,\N,synonymous_variant,0.066,0.0000149835,EXAC_NFE_AF,TSPEAR
504643,21:45959406:A>G,NM_198691.2:c.628T>C,NP_941964.2:p.Cys210Arg,1/1,\N,Unknown significance,\N,missense_variant,6.983,0.00011558,EXAC_EAS_AF,TSPEAR
504644,21:45959412:T>A,NM_198691.2:c.622A>T,NP_941964.2:p.Thr208Ser,1/1,\N,Unknown significance,\N,missense_variant,0.001,\N,\N,TSPEAR
504645,21:45959414:G>A,NM_198691.2:c.620C>T,NP_941964.2:p.Ser207Phe,1/1,\N,Unknown significance,\N,missense_variant,12.52,\N,\N,TSPEAR
504646,21:45959420:C>T,NM_198691.2:c.614G>A,NP_941964.2:p.Gly205Glu,1/1,\N,Unknown significance,\N,missense_variant,0.112,\N,\N,TSPEAR
504647,21:45959421:C>T,NM_198691.2:c.613G>A,NP_941964.2:p.Gly205Arg,1/1,\N,Unknown significance,\N,missense_variant,3.936,0.000697674,EVS_EA_AF,TSPEAR
504648,21:45959425:G>A,NM_198691.2:c.609C>T,NP_941964.2:p.Cys203=,1/1,\N,Unknown significance,\N,synonymous_variant,0.065,\N,\N,TSPEAR
504649,21:45959429:A>G,NM_198691.2:c.605T>C,NP_941964.2:p.Val202Ala,1/1,\N,Unknown significance,\N,missense_variant,0.94,0.0000150639,EXAC_NFE_AF,TSPEAR
504650,21:45959431:G>A,NM_198691.2:c.603C>T,NP_941964.2:p.Pro201=,1/1,\N,Unknown significance,\N,synonymous_variant,5.803,0.0008,1KG_AFR_AF,TSPEAR
504651,21:45959432:G>A,NM_198691.2:c.602C>T,NP_941964.2:p.Pro201Leu,1/1,\N,Unknown significance,\N,missense_variant,17.46,0.002,1KG_EAS_AF,TSPEAR
504652,21:45959432:G>C,NM_198691.2:c.602C>G,NP_941964.2:p.Pro201Arg,1/1,\N,Unknown significance,\N,missense_variant,13.08,0.000115554,EXAC_EAS_AF,TSPEAR
504653,21:45959436:C>CACAGCAGATGGGCTT,NM_198691.2:c.583_597dup,NP_941964.2:p.Lys195_Cys199dup,1/1,\N,Unknown significance,\N,inframe_insertion,0.011,\N,\N,TSPEAR
504654,21:45959436:C>T,NM_198691.2:c.598G>A,NP_941964.2:p.Val200Met,1/1,\N,Likely benign,\N,missense_variant,10.49,\N,\N,TSPEAR
504655,21:45959440:G>A,NM_198691.2:c.594C>T,NP_941964.2:p.Cys198=,1/1,\N,Unknown significance,\N,synonymous_variant,0.046,0.0000599341,EXAC_NFE_AF,TSPEAR
504656,21:45959444:A>T,NM_198691.2:c.590T>A,NP_941964.2:p.Ile197Asn,1/1,\N,Likely benign,\N,missense_variant,11.96,0.000226963,EVS_AA_AF,TSPEAR
504657,21:45959446:GGGCTTGCAGCAGACA>G,NM_198691.2:c.573_587del,NP_941964.2:p.Val192_Pro196del,1/1,\N,Unknown significance,\N,inframe_deletion,13.26,0.0000150209,EXAC_NFE_AF,TSPEAR
504658,21:45959446:G>A,NM_198691.2:c.588C>T,NP_941964.2:p.Pro196=,1/1,\N,Unknown significance,\N,synonymous_variant,0.025,0.000387147,EXAC_AFR_AF,TSPEAR
504659,21:45959449:C>T,NM_198691.2:c.585G>A,NP_941964.2:p.Lys195=,1/1,\N,Benign,\N,synonymous_variant,2.831,0.0348,1KG_AFR_AF,TSPEAR
504660,21:45959451:T>C,NM_198691.2:c.583A>G,NP_941964.2:p.Lys195Glu,1/1,\N,Likely benign,\N,missense_variant,1.437,0.000115607,EXAC_EAS_AF,TSPEAR
504661,21:45959452:G>A,NM_198691.2:c.582C>T,NP_941964.2:p.Cys194=,1/1,\N,Unknown significance,\N,synonymous_variant,0.329,0.003,1KG_EUR_AF,TSPEAR
504662,21:45959453:C>A,NM_198691.2:c.581G>T,NP_941964.2:p.Cys194Phe,1/1,\N,Benign,\N,missense_variant,18.59,0.0061,1KG_SAS_AF,TSPEAR
504663,21:45959454:A>G,NM_198691.2:c.580T>C,NP_941964.2:p.Cys194Arg,1/1,\N,Unknown significance,\N,missense_variant,18.58,0.0000449546,EXAC_NFE_AF,TSPEAR
504664,21:45959456:C>T,NM_198691.2:c.578G>A,NP_941964.2:p.Cys193Tyr,1/1,\N,Likely benign,\N,missense_variant,19.17,0.0000149844,EXAC_NFE_AF,TSPEAR
504665,21:45959458:G>A,NM_198691.2:c.576C>T,NP_941964.2:p.Val192=,1/1,\N,Unknown significance,\N,synonymous_variant,3.114,0.00278754,EXAC_SAS_AF,TSPEAR
504666,21:45959460:C>T,NM_198691.2:c.574G>A,NP_941964.2:p.Val192Ile,1/1,\N,Likely benign,\N,missense_variant,9.356,0.0000149844,EXAC_NFE_AF,TSPEAR
504667,21:45959470:A>G,NM_198691.2:c.564T>C,NP_941964.2:p.Arg188=,1/1,\N,Unknown significance,\N,synonymous_variant,1.225,0.003,1KG_AFR_AF|1KG_EUR_AF,TSPEAR
504668,21:45959471:C>T,NM_198691.2:c.563G>A,NP_941964.2:p.Arg188His,1/1,\N,Unknown significance,\N,missense_variant,23.4,0.00110132,EXAC_OTH_AF,TSPEAR
504669,21:45959472:G>A,NM_198691.2:c.562C>T,NP_941964.2:p.Arg188Cys,1/1,\N,Benign,\N,missense_variant,9.292,0.025,1KG_AFR_AF,TSPEAR
504670,21:45959475:C>T,NM_198691.2:c.559G>A,NP_941964.2:p.Val187Ile,1/1,\N,Likely benign,\N,missense_variant,9.469,0.000346901,EXAC_EAS_AF,TSPEAR
504671,21:45959476:G>A,NM_198691.2:c.558C>T,NP_941964.2:p.Pro186=,1/1,\N,Unknown significance,\N,synonymous_variant,10.01,0.003,1KG_EUR_AF,TSPEAR
504672,21:45959479:C>T,NM_198691.2:c.555G>A,NP_941964.2:p.Val185=,1/1,\N,Unknown significance,\N,synonymous_variant,8.988,\N,\N,TSPEAR
504673,21:45959480:A>T,NM_198691.2:c.554T>A,NP_941964.2:p.Val185Glu,1/1,\N,Likely benign,\N,missense_variant,8.364,\N,\N,TSPEAR
504674,21:45959481:C>G,NM_198691.2:c.553G>C,NP_941964.2:p.Val185Leu,1/1,\N,Unknown significance,\N,missense_variant,9.817,0.0000605694,EXAC_SAS_AF,TSPEAR
504675,21:45959481:C>T,NM_198691.2:c.553G>A,NP_941964.2:p.Val185Met,1/1,\N,Likely benign,\N,missense_variant,11.07,0.000231107,EXAC_EAS_AF,TSPEAR
504676,21:45959482:G>A,NM_198691.2:c.552C>T,NP_941964.2:p.Cys184=,1/1,\N,Benign,\N,synonymous_variant,5.955,0.0467,1KG_EUR_AF,TSPEAR
504677,21:45959482:G>C,NM_198691.2:c.552C>G,NP_941964.2:p.Cys184Trp,1/1,\N,Likely benign,\N,missense_variant,14.04,0.0000864304,EXAC_AMR_AF,TSPEAR
504678,21:45959483:C>T,NM_198691.2:c.551G>A,NP_941964.2:p.Cys184Tyr,1/1,\N,Likely benign,\N,missense_variant,1.38,0.0023,1KG_AFR_AF,TSPEAR
504679,21:45959490:C>A,NM_198691.2:c.544G>T,NP_941964.2:p.Ala182Ser,1/1,\N,Likely benign,\N,missense_variant,0.156,0.0014504,EXAC_AFR_AF,TSPEAR
504680,21:45959490:CCTGCTGGCAGGGGGAGGAGGTGCAGCAAGCTGGATGGCAGCTAGACTGCTGGCAGCATGAAGAGGAATCCTCAGAGCAGGTGGGCACATAGCACACAGGCTTGCAGCAAACAGGCACACAGCAGGA>C,NM_198691.2:c.418_543del,NP_941964.2:p.Ser140_Gln181del,1/1,\N,Unknown significance,\N,inframe_deletion,15.4,0.0000864304,EXAC_AMR_AF,TSPEAR
504681,21:45959498:C>T,NM_198691.2:c.536G>A,NP_941964.2:p.Cys179Tyr,1/1,\N,Unknown significance,\N,missense_variant,22.6,0.000116279,EVS_EA_AF,TSPEAR
504682,21:45959500:G>A,NM_198691.2:c.534C>T,NP_941964.2:p.Pro178=,1/1,\N,Unknown significance,\N,synonymous_variant,1.804,0.0000150002,EXAC_NFE_AF,TSPEAR
504683,21:45959501:G>A,NM_198691.2:c.533C>T,NP_941964.2:p.Pro178Leu,1/1,\N,Likely benign,\N,missense_variant,8.123,0.003,1KG_EAS_AF,TSPEAR
504684,21:45959502:G>A,NM_198691.2:c.532C>T,NP_941964.2:p.Pro178Ser,1/1,\N,Likely benign,\N,missense_variant,0.002,0.0000149903,EXAC_NFE_AF,TSPEAR
504685,21:45959502:G>T,NM_198691.2:c.532C>A,NP_941964.2:p.Pro178Thr,1/1,\N,Likely benign,\N,missense_variant,0.011,0.000096432,EXAC_AFR_AF,TSPEAR
504686,21:45959502:GGGA>G,NM_198691.2:c.529_531del,NP_941964.2:p.Ser177del,1/1,\N,Unknown significance,\N,inframe_deletion,0.006,0.000345602,EXAC_AMR_AF,TSPEAR
504687,21:45959503:GGA>G,NM_198691.2:c.529_530del,NP_941964.2:p.Ser177ProfsTer38,1/1,\N,Unknown significance,\N,frameshift_variant,12.87,0.000192641,EXAC_AFR_AF,TSPEAR
504688,21:45959506:G>A,NM_198691.2:c.528C>T,NP_941964.2:p.Ser176=,1/1,\N,Unknown significance,\N,synonymous_variant,0.065,0.000518762,EXAC_AMR_AF,TSPEAR
504689,21:45959508:A>C,NM_198691.2:c.526T>G,NP_941964.2:p.Ser176Ala,1/1,\N,Likely benign,\N,missense_variant,0.003,\N,\N,TSPEAR
504690,21:45959509:G>T,NM_198691.2:c.525C>A,NP_941964.2:p.Thr175=,1/1,\N,Unknown significance,\N,synonymous_variant,0.124,0.0013038,EXAC_NFE_AF,TSPEAR
504691,21:45959513:C>T,NM_198691.2:c.521G>A,NP_941964.2:p.Cys174Tyr,1/1,\N,Likely benign,\N,missense_variant,12.43,0.0000863856,EXAC_AMR_AF,TSPEAR
504692,21:45959519:G>A,NM_198691.2:c.515C>T,NP_941964.2:p.Ala172Val,1/1,\N,Unknown significance,\N,missense_variant,11.89,0.000346661,EXAC_EAS_AF,TSPEAR
504693,21:45959520:C>T,NM_198691.2:c.514G>A,NP_941964.2:p.Ala172Thr,1/1,\N,Likely benign,\N,missense_variant,7.298,\N,\N,TSPEAR
504694,21:45959521:T>C,NM_198691.2:c.513A>G,NP_941964.2:p.Pro171=,1/1,\N,Unknown significance,\N,synonymous_variant,0.019,\N,\N,TSPEAR
504695,21:45959524:A>ATGGCAGCTAGACTGC,NM_198691.2:c.495_509dup,NP_941964.2:p.Gln165_Cys169dup,1/1,\N,Unknown significance,\N,inframe_insertion,\N,\N,\N,TSPEAR
504696,21:45959524:A>C,NM_198691.2:c.510T>G,NP_941964.2:p.His170Gln,1/1,\N,Likely benign,\N,missense_variant,0.006,\N,\N,TSPEAR
504697,21:45959527:G>A,NM_198691.2:c.507C>T,NP_941964.2:p.Cys169=,1/1,\N,Unknown significance,\N,synonymous_variant,1.574,0.0000149853,EXAC_NFE_AF,TSPEAR
504698,21:45959529:A>G,NM_198691.2:c.505T>C,NP_941964.2:p.Cys169Arg,1/1,\N,Unknown significance,\N,missense_variant,20.2,0.0015,1KG_AFR_AF,TSPEAR
504699,21:45959533:A>G,NM_198691.2:c.501T>C,NP_941964.2:p.Ser167=,1/1,\N,Unknown significance,\N,synonymous_variant,0.566,0.000116279,EVS_EA_AF,TSPEAR
504700,21:45959536:C>A,NM_198691.2:c.498G>T,NP_941964.2:p.Gln166His,1/1,\N,Unknown significance,\N,missense_variant,10.63,0.0008,1KG_AFR_AF,TSPEAR
504701,21:45959539:C>T,NM_198691.2:c.495G>A,NP_941964.2:p.Gln165=,1/1,\N,Unknown significance,\N,synonymous_variant,1.193,0.0000149853,EXAC_NFE_AF,TSPEAR
504702,21:45959553:A>G,NM_198691.2:c.481T>C,NP_941964.2:p.Ser161Pro,1/1,\N,Likely benign,\N,missense_variant,0.698,\N,\N,TSPEAR
504703,21:45959556:A>ATG,NM_198691.2:c.477_478insCA,NP_941964.2:p.Ser160HisfsTer?,1/1,\N,Benign,\N,frameshift_variant,15.24,0.684429,EXAC_AFR_AF,TSPEAR
504704,21:45959556:A>G,NM_198691.2:c.478T>C,NP_941964.2:p.Ser160Pro,1/1,\N,Likely benign,\N,missense_variant,2.006,\N,\N,TSPEAR
504705,21:45959557:A>T,NM_198691.2:c.477T>A,NP_941964.2:p.Asp159Glu,1/1,\N,Benign,\N,missense_variant,0.023,0.6952,1KG_AFR_AF,TSPEAR
504706,21:45959557:ATC>A,NM_198691.2:c.475_476del,NP_941964.2:p.Asp159PhefsTer9,1/1,\N,Benign,\N,frameshift_variant,8.944,0.6883,EXAC_AFR_AF,TSPEAR
504707,21:45959557:ATC>TGA,NM_198691.2:c.475_477delinsTCA,NP_941964.2:p.Asp159Ser,1/1,\N,Unknown significance,\N,missense_variant,\N,\N,\N,TSPEAR
504708,21:45959558:T>G,NM_198691.2:c.476A>C,NP_941964.2:p.Asp159Ala,1/1,\N,Benign,\N,missense_variant,0.001,0.6952,1KG_AFR_AF,TSPEAR
504709,21:45959559:C>A,NM_198691.2:c.475G>T,NP_941964.2:p.Asp159Tyr,1/1,\N,Benign,\N,missense_variant,0.077,0.6952,1KG_AFR_AF,TSPEAR
504710,21:45959562:CAG>C,NM_198691.2:c.470_471del,NP_941964.2:p.Ser157Ter,1/1,\N,Unknown significance,\N,frameshift_variant,23.1,\N,\N,TSPEAR
504711,21:45959566:G>A,NM_198691.2:c.468C>T,NP_941964.2:p.Cys156=,1/1,\N,Unknown significance,\N,synonymous_variant,0.199,0.000014984,EXAC_NFE_AF,TSPEAR
504712,21:45959567:C>T,NM_198691.2:c.467G>A,NP_941964.2:p.Cys156Tyr,1/1,\N,Unknown significance,\N,missense_variant,13.86,0.001,1KG_SAS_AF,TSPEAR
504713,21:45959569:G>A,NM_198691.2:c.465C>T,NP_941964.2:p.Thr155=,1/1,\N,Unknown significance,\N,synonymous_variant,0.41,0.000060562,EXAC_SAS_AF,TSPEAR
504714,21:45959571:T>A,NM_198691.2:c.463A>T,NP_941964.2:p.Thr155Ser,1/1,\N,Likely benign,\N,missense_variant,0.003,\N,\N,TSPEAR
504715,21:45959579:T>C,NM_198691.2:c.455A>G,NP_941964.2:p.Tyr152Cys,1/1,\N,Likely benign,\N,missense_variant,0.002,0.0014,1KG_AMR_AF,TSPEAR
504716,21:45959583:A>T,NM_198691.2:c.451T>A,NP_941964.2:p.Cys151Ser,1/1,\N,Likely benign,\N,missense_variant,6.563,0.000193013,EXAC_AFR_AF,TSPEAR
504717,21:45959584:C>T,NM_198691.2:c.450G>A,NP_941964.2:p.Val150=,1/1,\N,Unknown significance,\N,synonymous_variant,7.34,0.000116279,EVS_EA_AF,TSPEAR
504718,21:45959587:A>G,NM_198691.2:c.447T>C,NP_941964.2:p.Pro149=,1/1,\N,Unknown significance,\N,synonymous_variant,0.005,0.0014,1KG_AMR_AF,TSPEAR
504719,21:45959590:C>T,NM_198691.2:c.444G>A,NP_941964.2:p.Lys148=,1/1,\N,Unknown significance,\N,synonymous_variant,7.513,0.000060562,EXAC_SAS_AF,TSPEAR
504720,21:45959599:A>G,NM_198691.2:c.435T>C,NP_941964.2:p.Val145=,1/1,\N,Unknown significance,\N,synonymous_variant,0.003,0.0014,1KG_AMR_AF,TSPEAR
504721,21:45959609:C>T,NM_198691.2:c.425G>A,NP_941964.2:p.Cys142Tyr,1/1,\N,Likely benign,\N,missense_variant,12.78,0.000115554,EXAC_EAS_AF,TSPEAR
504722,21:45959610:A>G,NM_198691.2:c.424T>C,NP_941964.2:p.Cys142Arg,1/1,\N,Unknown significance,\N,missense_variant,11.46,0.000151194,EXAC_FIN_AF,TSPEAR
504723,21:45959615:G>T,NM_198691.2:c.419C>A,NP_941964.2:p.Ser140Tyr,1/1,\N,Likely benign,\N,missense_variant,12.77,0.000060562,EXAC_SAS_AF,TSPEAR
504724,21:45959616:A>T,NM_198691.2:c.418T>A,NP_941964.2:p.Ser140Thr,1/1,\N,Likely benign,\N,missense_variant,0.002,0.001,1KG_EUR_AF,TSPEAR
504725,21:45959619:G>C,NM_198691.2:c.415C>G,NP_941964.2:p.Gln139Glu,1/1,\N,Likely benign,\N,missense_variant,0.005,0.0029036,EXAC_AFR_AF,TSPEAR
504726,21:45959622:G>T,NM_198691.2:c.412C>A,NP_941964.2:p.Gln138Lys,1/1,\N,Likely benign,\N,missense_variant,0.185,0.0000299679,EXAC_NFE_AF,TSPEAR
504727,21:45959625:T>A,NM_198691.2:c.409A>T,NP_941964.2:p.Ser137Cys,1/1,\N,Benign,\N,missense_variant,0.003,0.0229233,EVS_AA_AF,TSPEAR
504728,21:45959628:A>G,NM_198691.2:c.406T>C,NP_941964.2:p.Ser136Pro,1/1,\N,Likely benign,\N,missense_variant,0.003,\N,\N,TSPEAR
504729,21:45959632:A>G,NM_198691.2:c.402T>C,NP_941964.2:p.Ser134=,1/1,\N,Unknown significance,\N,synonymous_variant,0.056,\N,\N,TSPEAR
504730,21:45959637:C>T,NM_198691.2:c.397G>A,NP_941964.2:p.Ala133Thr,1/1,\N,Likely benign,\N,missense_variant,0.002,\N,\N,TSPEAR
504731,21:45959638:A>G,NM_198691.2:c.396T>C,NP_941964.2:p.Cys132=,1/1,\N,Unknown significance,\N,synonymous_variant,0.004,0.0000149862,EXAC_NFE_AF,TSPEAR
504732,21:45959638:A>T,NM_198691.2:c.396T>A,NP_941964.2:p.Cys132Ter,1/1,\N,Unknown significance,\N,stop_gained,28.5,0.0000599449,EXAC_NFE_AF,TSPEAR
504733,21:45959646:T>C,NM_198691.2:c.388A>G,NP_941964.2:p.Thr130Ala,1/1,\N,Likely benign,\N,missense_variant,0.001,0.000121124,EXAC_SAS_AF,TSPEAR
504734,21:45959649:G>A,NM_198691.2:c.385C>T,NP_941964.2:p.Pro129Ser,1/1,\N,Likely benign,\N,missense_variant,1.492,0.0014,1KG_AMR_AF,TSPEAR
504735,21:45959661:A>C,NM_198691.2:c.373T>G,NP_941964.2:p.Ser125Ala,1/1,\N,Likely benign,\N,missense_variant,1.349,0.000231214,EXAC_EAS_AF,TSPEAR
504736,21:45959661:A>G,NM_198691.2:c.373T>C,NP_941964.2:p.Ser125Pro,1/1,\N,Likely benign,\N,missense_variant,14.81,0.000115607,EXAC_EAS_AF,TSPEAR
504737,21:45959667:G>A,NM_198691.2:c.367C>T,NP_941964.2:p.Gln123Ter,1/1,\N,Unknown significance,\N,stop_gained,33,\N,\N,TSPEAR
504738,21:45959669:C>T,NM_198691.2:c.365G>A,NP_941964.2:p.Cys122Tyr,1/1,\N,Unknown significance,\N,missense_variant,18.9,0.0008,1KG_AFR_AF,TSPEAR
504739,21:45959674:T>C,NM_198691.2:c.360A>G,NP_941964.2:p.Ser120=,1/1,\N,Unknown significance,\N,synonymous_variant,0.1,0.001,1KG_EAS_AF,TSPEAR
504740,21:45959676:A>C,NM_198691.2:c.358T>G,NP_941964.2:p.Ser120Ala,1/1,\N,Likely benign,\N,missense_variant,0.07,\N,\N,TSPEAR
504741,21:45959678:G>A,NM_198691.2:c.356C>T,NP_941964.2:p.Ser119Phe,1/1,\N,Unknown significance,\N,missense_variant,13.55,0.000014993,EXAC_NFE_AF,TSPEAR
504742,21:45959680:G>C,NM_198691.2:c.354C>G,NP_941964.2:p.Ser118=,1/1,\N,Unknown significance,\N,synonymous_variant,0.011,\N,\N,TSPEAR
504743,21:45959685:C>G,NM_198691.2:c.349G>C,NP_941964.2:p.Asp117His,1/1,\N,Likely benign,\N,missense_variant,1.603,\N,\N,TSPEAR
504744,21:45959699:G>A,NM_198691.2:c.335C>T,NP_941964.2:p.Pro112Leu,1/1,\N,Unknown significance,\N,missense_variant,15.47,\N,\N,TSPEAR
504745,21:45959701:CAG>C,NM_198691.2:c.331_332del,NP_941964.2:p.Leu111AlafsTer5,1/1,\N,Unknown significance,\N,frameshift_variant,13.32,\N,\N,TSPEAR
504746,21:45959702:AGGCAGCACACAGGC>A,NM_198691.2:c.318_331del,NP_941964.2:p.Lys106AsnfsTer6,1/1,\N,Unknown significance,\N,frameshift_variant,25.8,\N,\N,TSPEAR
504747,21:45959704:G>GCA,NM_198691.2:c.328_329dup,NP_941964.2:p.Leu111AlafsTer?,1/1,\N,Unknown significance,\N,frameshift_variant,23,\N,\N,TSPEAR
504748,21:45959710:C>T,NM_198691.2:c.324G>A,NP_941964.2:p.Val108=,1/1,\N,Unknown significance,\N,synonymous_variant,5.665,\N,\N,TSPEAR
504749,21:45959712:C>T,NM_198691.2:c.322G>A,NP_941964.2:p.Val108Met,1/1,\N,Unknown significance,\N,missense_variant,16.48,\N,\N,TSPEAR
504750,21:45959716:C>T,NM_198691.2:c.318G>A,NP_941964.2:p.Lys106=,1/1,\N,Unknown significance,\N,synonymous_variant,8.031,\N,\N,TSPEAR
504751,21:45959717:T>TTGCA,NM_198691.2:c.313_316dup,NP_941964.2:p.Lys106MetfsTer12,1/1,\N,Unknown significance,\N,frameshift_variant,\N,\N,\N,TSPEAR
504752,21:45959717:TTGCAGCAGACGGGCAC>T,NM_198691.2:c.301_316del,NP_941964.2:p.Val101SerfsTer?,1/1,\N,Unknown significance,\N,frameshift_variant,31,\N,\N,TSPEAR
504753,21:45959719:G>A,NM_198691.2:c.315C>T,NP_941964.2:p.Cys105=,1/1,\N,Benign,\N,synonymous_variant,1.836,0.0069,1KG_EAS_AF,TSPEAR
504754,21:45959724:A>C,NM_198691.2:c.310T>G,NP_941964.2:p.Cys104Gly,1/1,\N,Unknown significance,\N,missense_variant,6.146,0.001,1KG_EAS_AF,TSPEAR
504755,21:45959727:C>T,NM_198691.2:c.307G>A,NP_941964.2:p.Val103Ile,1/1,\N,Likely benign,\N,missense_variant,8.047,0.00182149,EVS_AA_AF,TSPEAR
504756,21:45959728:G>A,NM_198691.2:c.306C>T,NP_941964.2:p.Pro102=,1/1,\N,Benign,\N,synonymous_variant,3.55,0.005,1KG_EAS_AF,TSPEAR
504757,21:45959730:G>C,NM_198691.2:c.304C>G,NP_941964.2:p.Pro102Ala,1/1,\N,Likely benign,\N,missense_variant,0.968,\N,\N,TSPEAR
504758,21:45959733:C>T,NM_198691.2:c.301G>A,NP_941964.2:p.Val101Met,1/1,\N,Benign,\N,missense_variant,13.27,0.683715,EXAC_AFR_AF,TSPEAR
504759,21:45959734:G>A,NM_198691.2:c.300C>T,NP_941964.2:p.Cys100=,1/1,\N,Benign,\N,synonymous_variant,3.146,0.005,1KG_EAS_AF,TSPEAR
504760,21:45959736:AGCAGGCCTGCTGGCAG>A,NM_198691.2:c.282_297del,NP_941964.2:p.Cys95AlafsTer?,1/1,\N,Unknown significance,\N,frameshift_variant,25.6,\N,\N,TSPEAR
504761,21:45959751:A>G,NM_198691.2:c.283T>C,NP_941964.2:p.Cys95Arg,1/1,\N,Unknown significance,\N,missense_variant,17.37,0.0000302489,EXAC_NFE_AF,TSPEAR
504762,21:45959751:A>T,NM_198691.2:c.283T>A,NP_941964.2:p.Cys95Ser,1/1,\N,Unknown significance,\N,missense_variant,14.82,0.000103627,EXAC_AFR_AF,TSPEAR
504763,21:45959752:G>T,NM_198691.2:c.282C>A,NP_941964.2:p.Pro94=,1/1,\N,Unknown significance,\N,synonymous_variant,0.078,\N,\N,TSPEAR
504764,21:45959755:G>T,NM_198691.2:c.279C>A,NP_941964.2:p.Ser93=,1/1,\N,Unknown significance,\N,synonymous_variant,0.694,\N,\N,TSPEAR
504765,21:45959757:A>G,NM_198691.2:c.277T>C,NP_941964.2:p.Ser93Pro,1/1,\N,Unknown significance,\N,missense_variant,13.94,\N,\N,TSPEAR
504766,21:45959758:G>A,NM_198691.2:c.276C>T,NP_941964.2:p.Ser92=,1/1,\N,Unknown significance,\N,synonymous_variant,0.401,\N,\N,TSPEAR
504767,21:45959762:G>T,NM_198691.2:c.272C>A,NP_941964.2:p.Thr91Asn,1/1,\N,Unknown significance,\N,missense_variant,9.582,\N,\N,TSPEAR
504768,21:45959763:T>C,NM_198691.2:c.271A>G,NP_941964.2:p.Thr91Ala,1/1,\N,Likely benign,\N,missense_variant,0.002,\N,\N,TSPEAR
504769,21:45959768:C>T,NM_198691.2:c.266G>A,NP_941964.2:p.Cys89Tyr,1/1,\N,Unknown significance,\N,missense_variant,21.3,\N,\N,TSPEAR
504770,21:45959773:C>T,NM_198691.2:c.261G>A,NP_941964.2:p.Pro87=,1/1,\N,Unknown significance,\N,synonymous_variant,11.61,\N,\N,TSPEAR
504771,21:45959774:G>A,NM_198691.2:c.260C>T,NP_941964.2:p.Pro87Leu,1/1,\N,Unknown significance,\N,missense_variant,23.2,0.002,1KG_EAS_AF,TSPEAR
504772,21:45959775:G>A,NM_198691.2:c.259C>T,NP_941964.2:p.Pro87Ser,1/1,\N,Unknown significance,\N,missense_variant,10.95,\N,\N,TSPEAR
504773,21:45959776:C>A,NM_198691.2:c.258G>T,NP_941964.2:p.Gln86His,1/1,\N,Unknown significance,\N,missense_variant,21.6,\N,\N,TSPEAR
504774,21:45959777:T>A,NM_198691.2:c.257A>T,NP_941964.2:p.Gln86Leu,1/1,\N,Unknown significance,\N,missense_variant,21.3,\N,\N,TSPEAR
504775,21:45959787:A>G,NM_198691.2:c.247T>C,NP_941964.2:p.Ser83Pro,1/1,\N,Unknown significance,\N,missense_variant,12.81,\N,\N,TSPEAR
504776,21:45959795:C>T,NM_198691.2:c.239G>A,NP_941964.2:p.Cys80Tyr,1/1,\N,Unknown significance,\N,missense_variant,15.66,\N,\N,TSPEAR
504777,21:45959797:G>A,NM_198691.2:c.237C>T,NP_941964.2:p.Cys79=,1/1,\N,Unknown significance,\N,synonymous_variant,1.003,\N,\N,TSPEAR
504778,21:45959800:C>T,NM_198691.2:c.234G>A,NP_941964.2:p.Ser78=,1/1,\N,Unknown significance,\N,synonymous_variant,12.07,0.0013975,EXAC_SAS_AF,TSPEAR
504779,21:45959801:G>A,NM_198691.2:c.233C>T,NP_941964.2:p.Ser78Leu,1/1,\N,Likely benign,\N,missense_variant,12.37,\N,\N,TSPEAR
504780,21:45959801:G>GAAGAGGATGACTC,NM_198691.2:c.232_233insGAGTCATCCTCTT,NP_941964.2:p.Ser78Ter,1/1,\N,Unknown significance,\N,stop_gained&frameshift_variant,21.8,\N,\N,TSPEAR
504781,21:45959802:A>AAGAGGATGACTCAGAGCAGGT,NM_198691.2:c.231_232insACCTGCTCTGAGTCATCCTCT,NP_941964.2:p.Pro77_Ser78insThrCysSerGluSerSerSer,1/1,\N,Unknown significance,\N,inframe_insertion,0.022,\N,\N,TSPEAR
504782,21:45959803:G>C,NM_198691.2:c.231C>G,NP_941964.2:p.Pro77=,1/1,\N,Unknown significance,\N,synonymous_variant,0.122,\N,\N,TSPEAR
504783,21:45959805:G>A,NM_198691.2:c.229C>T,NP_941964.2:p.Pro77Ser,1/1,\N,Likely benign,\N,missense_variant,3.072,\N,\N,TSPEAR
504784,21:45959806:C>T,NM_198691.2:c.228G>A,NP_941964.2:p.Thr76=,1/1,\N,Unknown significance,\N,synonymous_variant,10.07,\N,\N,TSPEAR
504785,21:45959807:G>A,NM_198691.2:c.227C>T,NP_941964.2:p.Thr76Met,1/1,\N,Likely benign,\N,missense_variant,8.922,\N,\N,TSPEAR
504786,21:45959815:G>C,NM_198691.2:c.219C>G,NP_941964.2:p.Ser73Arg,1/1,\N,Unknown significance,\N,missense_variant,22.3,\N,\N,TSPEAR
504787,21:45959818:G>T,NM_198691.2:c.216C>A,NP_941964.2:p.Thr72=,1/1,\N,Unknown significance,\N,synonymous_variant,2.736,\N,\N,TSPEAR
504788,21:45959821:G>A,NM_198691.2:c.213C>T,NP_941964.2:p.Cys71=,1/1,\N,Benign,\N,synonymous_variant,0.685,0.0908,1KG_AFR_AF,TSPEAR
504789,21:45959825:CCT>C,NM_198691.2:c.207_208del,NP_941964.2:p.Gly70LeufsTer14,1/1,\N,Unknown significance,\N,frameshift_variant,22.4,0.0000869565,EXAC_AMR_AF,TSPEAR
504790,21:45959830:T>C,NM_198691.2:c.204A>G,NP_941964.2:p.Gln68=,1/1,\N,Unknown significance,\N,synonymous_variant,0.007,0.00010582,EXAC_AFR_AF,TSPEAR
504791,21:45959830:T>G,NM_198691.2:c.204A>C,NP_941964.2:p.Gln68His,1/1,\N,Likely benign,\N,missense_variant,2.163,0.00197149,EXAC_FIN_AF,TSPEAR
504792,21:45959830:T>TTGGCAGGGGCTGGGCTCACAGGC,NM_198691.2:c.181_203dup,NP_941964.2:p.Ser69ProfsTer?,1/1,\N,Unknown significance,\N,frameshift_variant,17.61,0.000117288,EXAC_EAS_AF,TSPEAR
504793,21:45959838:G>C,NM_198691.2:c.196C>G,NP_941964.2:p.Pro66Ala,1/1,\N,Likely benign,\N,missense_variant,0.002,\N,\N,TSPEAR
504794,21:45959842:G>C,NM_198691.2:c.192C>G,NP_941964.2:p.Pro64=,1/1,\N,Unknown significance,\N,synonymous_variant,0.203,0.000242895,EXAC_SAS_AF,TSPEAR
504795,21:45959845:C>T,NM_198691.2:c.189G>A,NP_941964.2:p.Glu63=,1/1,\N,Unknown significance,\N,synonymous_variant,6.578,\N,\N,TSPEAR
504796,21:45959847:C>T,NM_198691.2:c.187G>A,NP_941964.2:p.Glu63Lys,1/1,\N,Likely benign,\N,missense_variant,9.707,0.0000151833,EXAC_NFE_AF,TSPEAR
504797,21:45959849:C>G,NM_198691.2:c.185G>C,NP_941964.2:p.Cys62Ser,1/1,\N,Likely benign,\N,missense_variant,10.11,0.001,1KG_EUR_AF,TSPEAR
504798,21:45959852:G>A,NM_198691.2:c.182C>T,NP_941964.2:p.Ala61Val,1/1,\N,Likely benign,\N,missense_variant,0.347,\N,\N,TSPEAR
504799,21:45959854:T>C,NM_198691.2:c.180A>G,NP_941964.2:p.Ala60=,1/1,\N,Unknown significance,\N,synonymous_variant,0.056,0.0015,1KG_AFR_AF,TSPEAR
504800,21:45959855:G>A,NM_198691.2:c.179C>T,NP_941964.2:p.Ala60Val,1/1,\N,Likely benign,\N,missense_variant,12.81,\N,\N,TSPEAR
504801,21:45959857:C>T,NM_198691.2:c.177G>A,NP_941964.2:p.Gln59=,1/1,\N,Unknown significance,\N,synonymous_variant,5.546,0.000116387,EVS_EA_AF,TSPEAR
504802,21:45959860:G>A,NM_198691.2:c.174C>T,NP_941964.2:p.Cys58=,1/1,\N,Benign,\N,synonymous_variant,7.438,0.0491,1KG_SAS_AF,TSPEAR
504803,21:45959862:A>G,NM_198691.2:c.172T>C,NP_941964.2:p.Cys58Arg,1/1,\N,Unknown significance,\N,missense_variant,13.49,0.000116414,EVS_EA_AF,TSPEAR
504804,21:45959867:G>A,NM_198691.2:c.167C>T,NP_941964.2:p.Pro56Leu,1/1,\N,Unknown significance,\N,missense_variant,25.9,0.001,1KG_EUR_AF,TSPEAR
504805,21:45959875:C>T,NM_198691.2:c.159G>A,NP_941964.2:p.Val53=,1/1,\N,Unknown significance,\N,synonymous_variant,14.26,0.000242925,EXAC_SAS_AF,TSPEAR
504806,21:45959879:C>T,NM_198691.2:c.155G>A,NP_941964.2:p.Arg52His,1/1,\N,Unknown significance,\N,missense_variant,24.6,0.001,1KG_EAS_AF,TSPEAR
504807,21:45959880:G>A,NM_198691.2:c.154C>T,NP_941964.2:p.Arg52Cys,1/1,\N,Likely benign,\N,missense_variant,14.93,\N,\N,TSPEAR
504808,21:45959881:G>A,NM_198691.2:c.153C>T,NP_941964.2:p.Ser51=,1/1,\N,Unknown significance,\N,synonymous_variant,10.02,0.0000607533,EXAC_SAS_AF,TSPEAR
504809,21:45959882:C>T,NM_198691.2:c.152G>A,NP_941964.2:p.Ser51Asn,1/1,\N,Unknown significance,\N,missense_variant,21.7,0.0000607533,EXAC_SAS_AF,TSPEAR
504810,21:45959884:C>T,NM_198691.2:c.150G>A,NP_941964.2:p.Val50=,1/1,\N,Unknown significance,\N,synonymous_variant,11.95,0.00139155,EXAC_AMR_AF,TSPEAR
504811,21:45959894:C>G,NM_198691.2:c.140G>C,NP_941964.2:p.Cys47Ser,1/1,\N,Unknown significance,\N,missense_variant,15.39,0.0000151368,EXAC_NFE_AF,TSPEAR
504812,21:45959894:C>T,NM_198691.2:c.140G>A,NP_941964.2:p.Cys47Tyr,1/1,\N,Unknown significance,\N,missense_variant,23.2,0.0000607607,EXAC_SAS_AF,TSPEAR
504813,21:45959898:C>A,NM_198691.2:c.136G>T,NP_941964.2:p.Val46Phe,1/1,\N,Likely benign,\N,missense_variant,16.47,0.000116713,EVS_EA_AF,TSPEAR
504814,21:45959902:G>T,NM_198691.2:c.132C>A,NP_941964.2:p.Thr44=,1/1,\N,Unknown significance,\N,synonymous_variant,4.519,0.0000607755,EXAC_SAS_AF,TSPEAR
504815,21:45959903:G>C,NM_198691.2:c.131C>G,NP_941964.2:p.Thr44Ser,1/1,\N,Likely benign,\N,missense_variant,9.334,0.00187882,EXAC_EAS_AF,TSPEAR
504816,21:45959904:T>G,NM_198691.2:c.130A>C,NP_941964.2:p.Thr44Pro,1/1,\N,Unknown significance,\N,missense_variant,18.62,0.0000151208,EXAC_NFE_AF,TSPEAR
504817,21:45959909:C>G,NM_198691.2:c.125G>C,NP_941964.2:p.Cys42Ser,1/1,\N,Likely benign,\N,missense_variant,16.43,0.00187793,EXAC_EAS_AF,TSPEAR
504818,21:45959911:G>A,NM_198691.2:c.123C>T,NP_941964.2:p.Pro41=,1/1,\N,Unknown significance,\N,synonymous_variant,7.397,0.0000302014,EXAC_NFE_AF,TSPEAR
504819,21:45959913:G>A,NM_198691.2:c.121C>T,NP_941964.2:p.Pro41Ser,1/1,\N,Likely benign,\N,missense_variant,10.86,\N,\N,TSPEAR
504820,21:45959914:G>A,NM_198691.2:c.120C>T,NP_941964.2:p.Ala40=,1/1,\N,Unknown significance,\N,synonymous_variant,8.652,0.00114061,EXAC_AFR_AF,TSPEAR
504821,21:45959915:G>T,NM_198691.2:c.119C>A,NP_941964.2:p.Ala40Asp,1/1,\N,Unknown significance,\N,missense_variant,24.9,0.000015093,EXAC_NFE_AF,TSPEAR
504822,21:45959916:C>T,NM_198691.2:c.118G>A,NP_941964.2:p.Ala40Thr,1/1,\N,Likely benign,\N,missense_variant,19.75,0.0014,1KG_AMR_AF,TSPEAR
504823,21:45959916:CCGGGGCGCAGCAGCTGAG>C,NM_198691.2:c.100_117del,NP_941964.2:p.Leu34_Pro39del,1/1,\N,Unknown significance,\N,inframe_deletion,13.84,\N,\N,TSPEAR
504824,21:45959917:C>T,NM_198691.2:c.117G>A,NP_941964.2:p.Pro39=,1/1,\N,Unknown significance,\N,synonymous_variant,13.93,0.00113083,EXAC_AMR_AF,TSPEAR
504825,21:45959917:CGGGGCGCAGCAGCTG>C,NM_198691.2:c.102_116del,NP_941964.2:p.Ser35_Pro39del,1/1,\N,Unknown significance,\N,inframe_deletion,14.01,0.000173974,EXAC_AMR_AF,TSPEAR
504826,21:45959918:G>A,NM_198691.2:c.116C>T,NP_941964.2:p.Pro39Leu,1/1,\N,Benign,\N,missense_variant,25,0.7428,1KG_AFR_AF,TSPEAR
504827,21:45959922:C>T,NM_198691.2:c.112G>A,NP_941964.2:p.Ala38Thr,1/1,\N,Likely benign,\N,missense_variant,19.76,0.000227169,EVS_AA_AF,TSPEAR
504828,21:45959923:G>A,NM_198691.2:c.111C>T,NP_941964.2:p.Cys37=,1/1,\N,Unknown significance,\N,synonymous_variant,0.593,0.00315863,EXAC_EAS_AF,TSPEAR
504829,21:45959931:T>A,NM_198691.2:c.103A>T,NP_941964.2:p.Ser35Cys,1/1,\N,Unknown significance,\N,missense_variant,22.2,0.000116768,EXAC_EAS_AF,TSPEAR
504830,21:45959933:A>G,NM_198691.2:c.101T>C,NP_941964.2:p.Leu34Pro,1/1,\N,Likely benign,\N,missense_variant,0.002,0.0023,1KG_AFR_AF,TSPEAR
504831,21:45959934:G>T,NM_198691.2:c.100C>A,NP_941964.2:p.Leu34Ile,1/1,\N,Unknown significance,\N,missense_variant,12.96,0.001,1KG_EAS_AF,TSPEAR
504832,21:45959935:G>A,NM_198691.2:c.99C>T,NP_941964.2:p.Ala33=,1/1,\N,Unknown significance,\N,synonymous_variant,4.796,\N,\N,TSPEAR
504833,21:45959937:C>T,NM_198691.2:c.97G>A,NP_941964.2:p.Ala33Thr,1/1,\N,Likely benign,\N,missense_variant,19.34,0.000583022,EXAC_EAS_AF,TSPEAR
504834,21:45959938:G>A,NM_198691.2:c.96C>T,NP_941964.2:p.Cys32=,1/1,\N,Unknown significance,\N,synonymous_variant,1.961,0.0029,1KG_AMR_AF,TSPEAR
504835,21:45959940:A>C,NM_198691.2:c.94T>G,NP_941964.2:p.Cys32Gly,1/1,\N,Unknown significance,\N,missense_variant,15.92,0.000202552,EXAC_AFR_AF,TSPEAR
504836,21:45959940:A>T,NM_198691.2:c.94T>A,NP_941964.2:p.Cys32Ser,1/1,\N,Unknown significance,\N,missense_variant,10.67,0.0000866852,EXAC_AMR_AF,TSPEAR
504837,21:45959945:T>G,NM_198691.2:c.89A>C,NP_941964.2:p.His30Pro,1/1,\N,Benign,\N,missense_variant,0.151,0.0115198,EXAC_AFR_AF,TSPEAR
504838,21:45959946:G>A,NM_198691.2:c.88C>T,NP_941964.2:p.His30Tyr,1/1,\N,Likely benign,\N,missense_variant,17.31,0.0000607091,EXAC_SAS_AF,TSPEAR
504839,21:45959947:G>A,NM_198691.2:c.87C>T,NP_941964.2:p.Pro29=,1/1,\N,Unknown significance,\N,synonymous_variant,7.649,\N,\N,TSPEAR
504840,21:45959948:G>T,NM_198691.2:c.86C>A,NP_941964.2:p.Pro29His,1/1,\N,Unknown significance,\N,missense_variant,24.9,\N,\N,TSPEAR
504841,21:45959950:C>T,NM_198691.2:c.84G>A,NP_941964.2:p.Glu28=,1/1,\N,Unknown significance,\N,synonymous_variant,12.33,0.001,1KG_EUR_AF,TSPEAR
504842,21:45959952:C>T,NM_198691.2:c.82G>A,NP_941964.2:p.Glu28Lys,1/1,\N,Unknown significance,\N,missense_variant,23.6,0.0000606796,EXAC_SAS_AF,TSPEAR
504843,21:45959953:A>G,NM_198691.2:c.81T>C,NP_941964.2:p.Cys27=,1/1,\N,Unknown significance,\N,synonymous_variant,0.613,0.000348109,EXAC_EAS_AF,TSPEAR
504844,21:45959953:ACAG>A,NM_198691.2:c.78_80del,NP_941964.2:p.Cys27del,1/1,\N,Benign,\N,inframe_deletion,19.92,0.0265,1KG_AFR_AF,TSPEAR
504845,21:45959962:C>T,NM_198691.2:c.72G>A,NP_941964.2:p.Glu24=,1/1,\N,Unknown significance,\N,synonymous_variant,10.36,0.0000149952,EXAC_NFE_AF,TSPEAR
504846,21:45959966:G>T,NM_198691.2:c.68C>A,NP_941964.2:p.Pro23Gln,1/1,\N,Unknown significance,\N,missense_variant,22.5,\N,\N,TSPEAR
504847,21:45959967:G>A,NM_198691.2:c.67C>T,NP_941964.2:p.Pro23Ser,1/1,\N,Unknown significance,\N,missense_variant,23.6,\N,\N,TSPEAR
504848,21:45959972:G>T,NM_198691.2:c.62C>A,NP_941964.2:p.Ala21Asp,1/1,\N,Benign,\N,missense_variant,0.005,0.015729,EXAC_FIN_AF,TSPEAR
504849,21:45959972:GCA>TCG,NM_198691.2:c.60_62delinsCGA,NP_941964.2:p.Ala21Asp,1/1,\N,Unknown significance,\N,missense_variant,1.585,\N,\N,TSPEAR
504850,21:45959973:C>T,NM_198691.2:c.61G>A,NP_941964.2:p.Ala21Thr,1/1,\N,Unknown significance,\N,missense_variant,17.24,0.0000149934,EXAC_NFE_AF,TSPEAR
504851,21:45959974:A>G,NM_198691.2:c.60T>C,NP_941964.2:p.Asp20=,1/1,\N,Benign,\N,synonymous_variant,0.021,0.0212,1KG_AFR_AF,TSPEAR
504852,21:45959991:C>T,NM_198691.2:c.43G>A,NP_941964.2:p.Asp15Asn,1/1,\N,Likely benign,\N,missense_variant,15.8,0.000060746,EXAC_SAS_AF,TSPEAR
504853,21:45959992:G>A,NM_198691.2:c.42C>T,NP_941964.2:p.Ser14=,1/1,\N,Unknown significance,\N,synonymous_variant,3.996,0.000693802,EXAC_EAS_AF,TSPEAR
504854,21:45959994:A>T,NM_198691.2:c.40T>A,NP_941964.2:p.Ser14Thr,1/1,\N,Likely benign,\N,missense_variant,0.005,0.0000149988,EXAC_NFE_AF,TSPEAR
504855,21:45959995:G>A,NM_198691.2:c.39C>T,NP_941964.2:p.Cys13=,1/1,\N,Unknown significance,\N,synonymous_variant,0.097,0.0000150011,EXAC_NFE_AF,TSPEAR
504856,21:45959996:C>T,NM_198691.2:c.38G>A,NP_941964.2:p.Cys13Tyr,1/1,\N,Likely benign,\N,missense_variant,0.001,0.000115607,EXAC_EAS_AF,TSPEAR
504857,21:45959999:G>C,NM_198691.2:c.35C>G,NP_941964.2:p.Ala12Gly,1/1,\N,Likely benign,\N,missense_variant,8.364,0.000115607,EXAC_EAS_AF,TSPEAR
504858,21:45960000:C>T,NM_198691.2:c.34G>A,NP_941964.2:p.Ala12Thr,1/1,\N,Likely benign,\N,missense_variant,0.015,0.0000608495,EXAC_SAS_AF,TSPEAR
504859,21:45960001:G>A,NM_198691.2:c.33C>T,NP_941964.2:p.Ser11=,1/1,\N,Unknown significance,\N,synonymous_variant,5.678,0.0000150056,EXAC_NFE_AF,TSPEAR
504860,21:45960005:G>A,NM_198691.2:c.29C>T,NP_941964.2:p.Ser10Phe,1/1,\N,Unknown significance,\N,missense_variant,23.5,0.000151194,EXAC_FIN_AF,TSPEAR
504861,21:45960009:A>G,NM_198691.2:c.25T>C,NP_941964.2:p.Cys9Arg,1/1,\N,Benign,\N,missense_variant,17.72,0.0234,1KG_AFR_AF,TSPEAR
504862,21:45960012:C>T,NM_198691.2:c.22G>A,NP_941964.2:p.Val8Ile,1/1,\N,Benign,\N,missense_variant,7.7,0.0234,1KG_AFR_AF,TSPEAR
504863,21:45960013:G>A,NM_198691.2:c.21C>T,NP_941964.2:p.Ser7=,1/1,\N,Unknown significance,\N,synonymous_variant,10.39,0.000030077,EXAC_NFE_AF,TSPEAR
504864,21:45960013:G>T,NM_198691.2:c.21C>A,NP_941964.2:p.Ser7=,1/1,\N,Unknown significance,\N,synonymous_variant,5.477,0.0000150385,EXAC_NFE_AF,TSPEAR
504865,21:45960017:A>G,NM_198691.2:c.17T>C,NP_941964.2:p.Met6Thr,1/1,\N,Unknown significance,\N,missense_variant,9.638,0.0000150435,EXAC_NFE_AF,TSPEAR
504866,21:45960025:C>T,NM_198691.2:c.9G>A,NP_941964.2:p.Ala3=,1/1,\N,Unknown significance,\N,synonymous_variant,11.25,0.0000643998,EXAC_SAS_AF,TSPEAR
504867,21:45960026:G>A,NM_198691.2:c.8C>T,NP_941964.2:p.Ala3Val,1/1,\N,Unknown significance,\N,missense_variant,18.32,0.0000644828,EXAC_SAS_AF,TSPEAR
504868,21:45960027:C>T,NM_198691.2:c.7G>A,NP_941964.2:p.Ala3Thr,1/1,\N,Likely benign,\N,missense_variant,13.11,0.002,1KG_EAS_AF,TSPEAR
504869,21:45960028:G>A,NM_198691.2:c.6C>T,NP_941964.2:p.Ala2=,1/1,\N,Unknown significance,\N,synonymous_variant,7.759,0.000302389,EXAC_FIN_AF,TSPEAR
504870,21:45960029:G>T,NM_198691.2:c.5C>A,NP_941964.2:p.Ala2Asp,1/1,\N,Unknown significance,\N,missense_variant,23,0.0000653766,EXAC_SAS_AF,TSPEAR
504871,21:45960032:A>C,NM_198691.2:c.2T>G,NP_941964.2:p.Met1?,1/1,\N,Likely benign,\N,start_lost,4.188,0.000197239,EXAC_SAS_AF,TSPEAR
504872,21:45960038:G>C,NM_198691.2:c.-5C>G,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,0.564,0.000116279,EVS_EA_AF,TSPEAR
504873,21:45960039:G>A,NM_198691.2:c.-6C>T,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,1.771,0.0000675767,EXAC_SAS_AF,TSPEAR
504874,21:45960043:GGGA>G,NM_198691.2:c.-13_-11del,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,4.616,0.000015163,EXAC_NFE_AF,TSPEAR
504875,21:45960043:G>C,NM_198691.2:c.-10C>G,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,0.291,0.000115821,EXAC_EAS_AF,TSPEAR
504876,21:45960046:AGGAGGTGAGCTGCG>A,NM_198691.2:c.-27_-14del,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,8.111,\N,\N,TSPEAR
504877,21:45960058:G>T,NM_198691.2:c.-25C>A,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,8.804,0.000076266,EXAC_SAS_AF,TSPEAR
504878,21:45960059:C>A,NM_198691.2:c.-26G>T,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,7.429,0.0000152658,EXAC_NFE_AF,TSPEAR
504879,21:45960059:C>G,NM_198691.2:c.-26G>C,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,4.447,0.0000976944,EXAC_AFR_AF,TSPEAR
504880,21:45960059:C>T,NM_198691.2:c.-26G>A,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,6.914,0.00068089,EVS_AA_AF,TSPEAR
504881,21:45960061:G>A,NM_198691.2:c.-28C>T,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,4.165,0.0000866701,EXAC_AMR_AF,TSPEAR
504882,21:45960065:G>A,NM_198691.2:c.-32C>T,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,4.848,0.00011609,EXAC_EAS_AF,TSPEAR
504883,21:45960066:T>C,NM_198691.2:c.-33A>G,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,3.56,0.0000817127,EXAC_SAS_AF,TSPEAR
504884,21:45960066:TGTGA>T,NM_198691.2:c.-37_-34del,\N,1/1,\N,Benign,\N,5_prime_UTR_variant,6.691,0.00726392,EXAC_OTH_AF,TSPEAR
504885,21:45960072:T>C,NM_198691.2:c.-39A>G,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,0.858,0.0000153633,EXAC_NFE_AF,TSPEAR
504886,21:45960078:A>C,NM_198691.2:c.-45T>G,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,2.852,0.000293657,EXAC_AFR_AF,TSPEAR
504887,21:45960084:G>T,NM_144991.2:c.304-6278C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.818,0.0000308871,EXAC_NFE_AF,TSPEAR
504888,21:45960085:G>C,NM_144991.2:c.304-6279C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,2.354,0.000272876,EXAC_SAS_AF,TSPEAR
504889,21:45960091:G>A,NM_144991.2:c.304-6285C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.898,\N,\N,TSPEAR
504890,21:45960094:T>A,NM_144991.2:c.304-6288A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.448,\N,\N,TSPEAR
504891,21:45960107:C>CTGAG,NM_144991.2:c.304-6305_304-6302dup,\N,\N,2/11,Unknown significance,\N,intron_variant,5.599,0.0045,1KG_AFR_AF,TSPEAR
504892,21:45960117:G>A,NM_144991.2:c.304-6311C>T,\N,\N,2/11,Benign,\N,intron_variant,7.381,0.0204,1KG_SAS_AF,TSPEAR
504893,21:45960119:G>A,NM_144991.2:c.304-6313C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,10.53,0.0014,1KG_AMR_AF,TSPEAR
504894,21:45960119:G>GTGAC,NM_144991.2:c.304-6314_304-6313insGTCA,\N,\N,2/11,Benign,\N,intron_variant,9.222,0.0248,1KG_EAS_AF,TSPEAR
504895,21:45960136:G>C,NM_144991.2:c.304-6330C>G,\N,\N,2/11,Benign,\N,intron_variant,0.061,0.0061,1KG_SAS_AF,TSPEAR
504896,21:45960136:G>T,NM_144991.2:c.304-6330C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.147,0.003,1KG_EUR_AF,TSPEAR
504897,21:45960145:T>C,NM_144991.2:c.304-6339A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.144,0.0045,1KG_AFR_AF,TSPEAR
504898,21:45960195:T>C,NM_144991.2:c.304-6389A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,5.48,0.001,1KG_SAS_AF,TSPEAR
504899,21:45960197:C>T,NM_144991.2:c.304-6391G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,9.905,\N,\N,TSPEAR
504900,21:45960214:G>A,NM_144991.2:c.304-6408C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.281,0.002,1KG_SAS_AF,TSPEAR
504901,21:45960258:C>T,NM_144991.2:c.304-6452G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.938,0.001,1KG_EUR_AF,TSPEAR
504902,21:45960266:T>C,NM_144991.2:c.304-6460A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.575,\N,\N,TSPEAR
504903,21:45960302:A>C,NM_144991.2:c.304-6496T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,2.851,\N,\N,TSPEAR
504904,21:45960312:C>T,NM_144991.2:c.304-6506G>A,\N,\N,2/11,Benign,\N,intron_variant,1.145,0.006,1KG_EUR_AF,TSPEAR
504905,21:45960348:C>T,NM_144991.2:c.304-6542G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.992,\N,\N,TSPEAR
504906,21:45960356:G>A,NM_144991.2:c.304-6550C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.178,\N,\N,TSPEAR
504907,21:45960364:C>T,NM_144991.2:c.304-6558G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.596,0.0015,1KG_AFR_AF,TSPEAR
504908,21:45960367:G>A,NM_144991.2:c.304-6561C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.863,\N,\N,TSPEAR
504909,21:45960386:G>A,NM_144991.2:c.304-6580C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.394,\N,\N,TSPEAR
504910,21:45960396:G>A,NM_144991.2:c.304-6590C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.636,0.001,1KG_SAS_AF,TSPEAR
504911,21:45960435:T>C,NM_144991.2:c.304-6629A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.735,0.0038,1KG_AFR_AF,TSPEAR
504912,21:45960457:C>T,NM_144991.2:c.304-6651G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.15,0.0038,1KG_AFR_AF,TSPEAR
504913,21:45960458:G>A,NM_144991.2:c.304-6652C>T,\N,\N,2/11,Benign,\N,intron_variant,0.004,0.006,1KG_EAS_AF,TSPEAR
504914,21:45960464:G>A,NM_144991.2:c.304-6658C>T,\N,\N,2/11,Benign,\N,intron_variant,3.58,0.0174,1KG_AFR_AF,TSPEAR
504915,21:45960466:G>A,NM_144991.2:c.304-6660C>T,\N,\N,2/11,Benign,\N,intron_variant,1.219,0.0287,1KG_AFR_AF,TSPEAR
504916,21:45960508:G>A,NM_144991.2:c.304-6702C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,5.427,0.0015,1KG_AFR_AF,TSPEAR
504917,21:45960539:C>T,NM_144991.2:c.304-6733G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.015,0.0038,1KG_AFR_AF,TSPEAR
504918,21:45960541:G>C,NM_144991.2:c.304-6735C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.639,\N,\N,TSPEAR
504919,21:45960543:G>T,NM_144991.2:c.304-6737C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.344,\N,\N,TSPEAR
504920,21:45960545:G>A,NM_144991.2:c.304-6739C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.12,\N,\N,TSPEAR
504921,21:45960568:A>G,NM_144991.2:c.304-6762T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,3.844,0.0045,1KG_AFR_AF,TSPEAR
504922,21:45960579:G>A,NM_144991.2:c.304-6773C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.993,0.0014,1KG_AMR_AF,TSPEAR
504923,21:45960613:C>T,NM_144991.2:c.304-6807G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.285,\N,\N,TSPEAR
504924,21:45960628:C>T,NM_144991.2:c.304-6822G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,5.055,0.0015,1KG_AFR_AF,TSPEAR
504925,21:45960631:C>T,NM_144991.2:c.304-6825G>A,\N,\N,2/11,Benign,\N,intron_variant,2.9,0.0356,1KG_AFR_AF,TSPEAR
504926,21:45960680:G>A,NM_144991.2:c.304-6874C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.607,0.0008,1KG_AFR_AF,TSPEAR
504927,21:45960704:C>T,NM_144991.2:c.304-6898G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.466,0.0045,1KG_AFR_AF,TSPEAR
504928,21:45960705:G>A,NM_144991.2:c.304-6899C>T,\N,\N,2/11,Benign,\N,intron_variant,0.095,0.0248,1KG_EAS_AF,TSPEAR
504929,21:45960736:G>A,NM_144991.2:c.304-6930C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,5.956,0.002,1KG_EUR_AF,TSPEAR
504930,21:45960737:T>A,NM_144991.2:c.304-6931A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,7.085,0.0015,1KG_AFR_AF,TSPEAR
504931,21:45960740:C>T,NM_144991.2:c.304-6934G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.255,\N,\N,TSPEAR
504932,21:45960765:T>G,NM_144991.2:c.304-6959A>C,\N,\N,2/11,Unknown significance,\N,intron_variant,4.213,0.0015,1KG_AFR_AF,TSPEAR
504933,21:45960771:A>G,NM_144991.2:c.304-6965T>C,\N,\N,2/11,Benign,\N,intron_variant,6.975,0.0711,1KG_AFR_AF,TSPEAR
504934,21:45960797:C>T,NM_144991.2:c.304-6991G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.086,0.001,1KG_SAS_AF,TSPEAR
504935,21:45960820:C>T,NM_144991.2:c.304-7014G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.497,\N,\N,TSPEAR
504936,21:45960840:G>A,NM_144991.2:c.304-7034C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.585,0.0045,1KG_AFR_AF,TSPEAR
504937,21:45960861:A>ATTT,NM_144991.2:c.304-7058_304-7056dup,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
504938,21:45960861:AT>A,NM_144991.2:c.304-7056del,\N,\N,2/11,Benign,\N,intron_variant,0.241,0.1407,1KG_AFR_AF,TSPEAR
504939,21:45960864:T>A,NM_144991.2:c.304-7058A>T,\N,\N,2/11,Benign,\N,intron_variant,2.779,0.0318,1KG_AFR_AF,TSPEAR
504940,21:45960864:T>TA,NM_144991.2:c.304-7059_304-7058insT,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
504941,21:45960865:T>A,NM_144991.2:c.304-7059A>T,\N,\N,2/11,Benign,\N,intron_variant,2.349,0.0575,1KG_EAS_AF,TSPEAR
504942,21:45960866:T>A,NM_144991.2:c.304-7060A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.454,\N,\N,TSPEAR
504943,21:45960867:T>A,NM_144991.2:c.304-7061A>T,\N,\N,2/11,Benign,\N,intron_variant,2.234,0.0106,1KG_AFR_AF,TSPEAR
504944,21:45960877:G>T,NM_144991.2:c.304-7071C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.9,\N,\N,TSPEAR
504945,21:45960880:C>T,NM_144991.2:c.304-7074G>A,\N,\N,2/11,Benign,\N,intron_variant,6.508,0.0278,1KG_EUR_AF,TSPEAR
504946,21:45960887:C>T,NM_144991.2:c.304-7081G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,6.696,\N,\N,TSPEAR
504947,21:45960888:G>A,NM_144991.2:c.304-7082C>T,\N,\N,2/11,Benign,\N,intron_variant,8.676,0.0378,1KG_EUR_AF,TSPEAR
504948,21:45960889:T>C,NM_144991.2:c.304-7083A>G,\N,\N,2/11,Benign,\N,intron_variant,8.401,0.0051,1KG_SAS_AF,TSPEAR
504949,21:45960900:C>T,NM_144991.2:c.304-7094G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,11.37,0.0015,1KG_AFR_AF,TSPEAR
504950,21:45960932:A>G,NM_144991.2:c.304-7126T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,3.421,0.0038,1KG_AFR_AF,TSPEAR
504951,21:45960936:G>A,NM_144991.2:c.304-7130C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.297,0.001,1KG_EAS_AF,TSPEAR
504952,21:45960943:C>T,NM_144991.2:c.304-7137G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.54,0.0008,1KG_AFR_AF,TSPEAR
504953,21:45960944:G>A,NM_144991.2:c.304-7138C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.882,0.004,1KG_EUR_AF,TSPEAR
504954,21:45960975:A>T,NM_144991.2:c.304-7169T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.168,0.001,1KG_EAS_AF,TSPEAR
504955,21:45960976:C>T,NM_144991.2:c.304-7170G>A,\N,\N,2/11,Benign,\N,intron_variant,3.244,0.0893,1KG_AFR_AF,TSPEAR
504956,21:45960998:A>G,NM_144991.2:c.304-7192T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.829,0.001,1KG_EAS_AF,TSPEAR
504957,21:45961008:C>T,NM_144991.2:c.304-7202G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,7.389,0.003,1KG_EUR_AF,TSPEAR
504958,21:45961029:C>T,NM_144991.2:c.304-7223G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.778,\N,\N,TSPEAR
504959,21:45961044:T>C,NM_144991.2:c.304-7238A>G,\N,\N,2/11,Benign,\N,intron_variant,1.746,0.0068,1KG_AFR_AF,TSPEAR
504960,21:45961066:C>T,NM_144991.2:c.304-7260G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,8.889,\N,\N,TSPEAR
504961,21:45961070:T>G,NM_144991.2:c.304-7264A>C,\N,\N,2/11,Benign,\N,intron_variant,8.194,0.0121,1KG_AFR_AF,TSPEAR
504962,21:45961079:C>T,NM_144991.2:c.304-7273G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,8.594,0.001,1KG_EAS_AF,TSPEAR
504963,21:45961104:C>T,NM_144991.2:c.304-7298G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.014,\N,\N,TSPEAR
504964,21:45961120:G>A,NM_144991.2:c.304-7314C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.574,\N,\N,TSPEAR
504965,21:45961149:A>G,NM_144991.2:c.304-7343T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.293,\N,\N,TSPEAR
504966,21:45961187:C>T,NM_144991.2:c.304-7381G>A,\N,\N,2/11,Benign,\N,intron_variant,2.779,0.0174,1KG_AFR_AF,TSPEAR
504967,21:45961194:C>T,NM_144991.2:c.304-7388G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.105,0.002,1KG_EUR_AF,TSPEAR
504968,21:45961207:C>A,NM_144991.2:c.304-7401G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,7.065,0.0038,1KG_AFR_AF,TSPEAR
504969,21:45961216:T>A,NM_144991.2:c.304-7410A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,7.967,\N,\N,TSPEAR
504970,21:45961224:T>C,NM_144991.2:c.304-7418A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,6.541,\N,\N,TSPEAR
504971,21:45961255:G>A,NM_144991.2:c.304-7449C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.22,0.001,1KG_EAS_AF,TSPEAR
504972,21:45961276:A>G,NM_144991.2:c.304-7470T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,3.369,0.001,1KG_EAS_AF|1KG_SAS_AF,TSPEAR
504973,21:45961280:G>A,NM_144991.2:c.304-7474C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.931,\N,\N,TSPEAR
504974,21:45961307:G>A,NM_144991.2:c.304-7501C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,6.003,\N,\N,TSPEAR
504975,21:45961339:G>A,NM_144991.2:c.304-7533C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.056,0.0029,1KG_AMR_AF,TSPEAR
504976,21:45961347:C>T,NM_144991.2:c.304-7541G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.086,0.001,1KG_EAS_AF|1KG_SAS_AF,TSPEAR
504977,21:45961369:G>A,NM_144991.2:c.304-7563C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,6.538,\N,\N,TSPEAR
504978,21:45961387:C>T,NM_144991.2:c.304-7581G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,6.104,0.0008,1KG_AFR_AF,TSPEAR
504979,21:45961388:G>T,NM_144991.2:c.304-7582C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.68,0.0008,1KG_AFR_AF,TSPEAR
504980,21:45961412:G>A,NM_144991.2:c.304-7606C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.916,0.0014,1KG_AMR_AF,TSPEAR
504981,21:45961440:T>C,NM_144991.2:c.304-7634A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.693,\N,\N,TSPEAR
504982,21:45961443:C>T,NM_144991.2:c.304-7637G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.704,0.0045,1KG_AFR_AF,TSPEAR
504983,21:45961447:G>A,NM_144991.2:c.304-7641C>T,\N,\N,2/11,Benign,\N,intron_variant,3.008,0.1437,1KG_AFR_AF,TSPEAR
504984,21:45961458:A>G,NM_144991.2:c.304-7652T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,3.22,0.001,1KG_SAS_AF,TSPEAR
504985,21:45961468:C>T,NM_144991.2:c.304-7662G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.263,0.003,1KG_AFR_AF,TSPEAR
504986,21:45961469:A>G,NM_144991.2:c.304-7663T>C,\N,\N,2/11,Benign,\N,intron_variant,3.703,0.0082,1KG_SAS_AF,TSPEAR
504987,21:45961483:G>A,NM_144991.2:c.304-7677C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.291,0.0008,1KG_AFR_AF,TSPEAR
504988,21:45961491:G>A,NM_144991.2:c.304-7685C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.85,\N,\N,TSPEAR
504989,21:45961491:G>C,NM_144991.2:c.304-7685C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.866,0.0015,1KG_AFR_AF,TSPEAR
504990,21:45961506:G>A,NM_144991.2:c.304-7700C>T,\N,\N,2/11,Benign,\N,intron_variant,3.275,0.0628,1KG_AFR_AF,TSPEAR
504991,21:45961509:T>C,NM_144991.2:c.304-7703A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.928,0.0015,1KG_AFR_AF,TSPEAR
504992,21:45961529:A>C,NM_144991.2:c.304-7723T>G,\N,\N,2/11,Benign,\N,intron_variant,2.751,0.0325,1KG_AFR_AF,TSPEAR
504993,21:45961533:GA>G,NM_144991.2:c.304-7728del,\N,\N,2/11,Unknown significance,\N,intron_variant,2.163,0.0038,1KG_AFR_AF,TSPEAR
504994,21:45961533:GAAA>G,NM_144991.2:c.304-7730_304-7728del,\N,\N,2/11,Unknown significance,\N,intron_variant,1.97,0.003,1KG_AFR_AF,TSPEAR
504995,21:45961540:A>C,NM_144991.2:c.304-7734T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,3.402,0.0008,1KG_AFR_AF,TSPEAR
504996,21:45961566:T>C,NM_144991.2:c.304-7760A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,2.992,\N,\N,TSPEAR
504997,21:45961588:C>T,NM_144991.2:c.304-7782G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.468,\N,\N,TSPEAR
504998,21:45961668:C>G,NM_144991.2:c.304-7862G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.103,0.0038,1KG_AFR_AF,TSPEAR
504999,21:45961762:C>T,NM_144991.2:c.304-7956G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,5.005,\N,\N,TSPEAR
505000,21:45961774:C>T,NM_144991.2:c.304-7968G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.48,\N,\N,TSPEAR
505001,21:45961848:C>G,NM_144991.2:c.304-8042G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,5.059,0.001,1KG_EAS_AF,TSPEAR
505002,21:45961863:A>G,NM_144991.2:c.304-8057T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,6.898,\N,\N,TSPEAR
505003,21:45961879:C>A,NM_144991.2:c.304-8073G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,5.316,\N,\N,TSPEAR
505004,21:45961883:CAA>C,NM_144991.2:c.304-8079_304-8078del,\N,\N,2/11,Benign,\N,intron_variant,8.241,0.0076,1KG_AFR_AF,TSPEAR
505005,21:45961897:G>A,NM_144991.2:c.304-8091C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.027,\N,\N,TSPEAR
505006,21:45961913:T>A,NM_144991.2:c.304-8107A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,4.532,\N,\N,TSPEAR
505007,21:45961959:G>A,NM_144991.2:c.304-8153C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.689,0.001,1KG_EUR_AF,TSPEAR
505008,21:45961969:A>G,NM_144991.2:c.304-8163T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.311,0.002,1KG_EUR_AF,TSPEAR
505009,21:45961971:C>G,NM_144991.2:c.304-8165G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.493,\N,\N,TSPEAR
505010,21:45962009:T>C,NM_144991.2:c.304-8203A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,3.949,\N,\N,TSPEAR
505011,21:45962029:G>A,NM_144991.2:c.304-8223C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,6.992,0.003,1KG_AFR_AF,TSPEAR
505012,21:45962030:G>T,NM_144991.2:c.304-8224C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.305,0.001,1KG_EUR_AF,TSPEAR
505013,21:45962034:C>T,NM_144991.2:c.304-8228G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,8.084,\N,\N,TSPEAR
505014,21:45962040:A>T,NM_144991.2:c.304-8234T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,7.893,0.0045,1KG_AFR_AF,TSPEAR
505015,21:45962045:A>G,NM_144991.2:c.304-8239T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,9.397,0.002,1KG_SAS_AF,TSPEAR
505016,21:45962084:A>G,NM_144991.2:c.304-8278T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,7.288,\N,\N,TSPEAR
505017,21:45962095:A>G,NM_144991.2:c.304-8289T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,12.64,\N,\N,TSPEAR
505018,21:45962127:G>A,NM_144991.2:c.304-8321C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,13.39,\N,\N,TSPEAR
505019,21:45962132:A>G,NM_144991.2:c.304-8326T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,13.5,\N,\N,TSPEAR
505020,21:45962163:A>G,NM_144991.2:c.304-8357T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,9.37,\N,\N,TSPEAR
505021,21:45962169:G>T,NM_144991.2:c.304-8363C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,6.683,\N,\N,TSPEAR
505022,21:45962202:T>G,NM_144991.2:c.304-8396A>C,\N,\N,2/11,Unknown significance,\N,intron_variant,7.638,0.001,1KG_SAS_AF,TSPEAR
505023,21:45962216:A>T,NM_144991.2:c.304-8410T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.433,0.004,1KG_EUR_AF,TSPEAR
505024,21:45962220:A>G,NM_144991.2:c.304-8414T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,8.005,\N,\N,TSPEAR
505025,21:45962256:T>A,NM_144991.2:c.304-8450A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,8.52,0.0045,1KG_AFR_AF,TSPEAR
505026,21:45962278:T>C,NM_144991.2:c.304-8472A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,2.739,0.001,1KG_EUR_AF,TSPEAR
505027,21:45962311:T>G,NM_144991.2:c.304-8505A>C,\N,\N,2/11,Benign,\N,intron_variant,2.733,0.3241,1KG_SAS_AF,TSPEAR
505028,21:45962356:C>T,NM_144991.2:c.304-8550G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.764,\N,\N,TSPEAR
505029,21:45962371:C>G,NM_144991.2:c.304-8565G>C,\N,\N,2/11,Benign,\N,intron_variant,4.768,0.2413,1KG_SAS_AF,TSPEAR
505030,21:45962388:T>TG,NM_144991.2:c.304-8583dup,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
505031,21:45962422:G>A,NM_144991.2:c.304-8616C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,4.422,\N,\N,TSPEAR
505032,21:45962440:G>C,NM_144991.2:c.304-8634C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,2.397,0.0014,1KG_AMR_AF,TSPEAR
505033,21:45962460:A>G,NM_144991.2:c.304-8654T>C,\N,\N,2/11,Benign,\N,intron_variant,4.406,0.0053,1KG_AFR_AF,TSPEAR
505034,21:45962496:G>A,NM_144991.2:c.304-8690C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.326,\N,\N,TSPEAR
505035,21:45962502:C>T,NM_144991.2:c.304-8696G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,6,0.0008,1KG_AFR_AF,TSPEAR
505036,21:45962503:A>G,NM_144991.2:c.304-8697T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,4.485,0.0015,1KG_AFR_AF,TSPEAR
505037,21:45962515:A>C,NM_144991.2:c.304-8709T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,5.576,\N,\N,TSPEAR
505038,21:45962554:G>T,NM_144991.2:c.304-8748C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.324,0.0029,1KG_AMR_AF,TSPEAR
505039,21:45962566:C>CT,NM_144991.2:c.304-8761dup,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
505040,21:45962624:T>A,NM_144991.2:c.304-8818A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,8.294,\N,\N,TSPEAR
505041,21:45962625:T>TA,NM_144991.2:c.304-8820dup,\N,\N,2/11,Benign,\N,intron_variant,7.054,0.8896,1KG_AFR_AF,TSPEAR
505042,21:45962627:A>G,NM_144991.2:c.304-8821T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,6.849,\N,\N,TSPEAR
505043,21:45962642:G>A,NM_144991.2:c.304-8836C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,10.49,\N,\N,TSPEAR
505044,21:45962643:A>G,NM_144991.2:c.304-8837T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,8.918,0.0031,1KG_SAS_AF,TSPEAR
505045,21:45962689:A>G,NM_144991.2:c.304-8883T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,12.16,\N,\N,TSPEAR
505046,21:45962731:C>A,NM_144991.2:c.304-8925G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,14.29,0.001,1KG_EUR_AF,TSPEAR
505047,21:45962809:C>G,NM_144991.2:c.304-9003G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,11.08,\N,\N,TSPEAR
505048,21:45962865:T>C,NM_144991.2:c.304-9059A>G,\N,\N,2/11,Benign,\N,intron_variant,9.742,0.413,1KG_AFR_AF,TSPEAR
505049,21:45962866:G>A,NM_144991.2:c.304-9060C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,11.44,\N,\N,TSPEAR
505050,21:45962876:A>G,NM_144991.2:c.304-9070T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,10.85,\N,\N,TSPEAR
505051,21:45962905:A>G,NM_144991.2:c.304-9099T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,11.7,0.0014,1KG_AMR_AF,TSPEAR
505052,21:45962928:G>A,NM_144991.2:c.304-9122C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,13.19,0.002,1KG_SAS_AF,TSPEAR
505053,21:45962949:C>G,NM_144991.2:c.304-9143G>C,\N,\N,2/11,Benign,\N,intron_variant,8.858,0.0098,1KG_AFR_AF,TSPEAR
505054,21:45962950:A>G,NM_144991.2:c.304-9144T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,7.302,0.0014,1KG_AMR_AF,TSPEAR
505055,21:45962962:T>C,NM_144991.2:c.304-9156A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,2.018,0.0008,1KG_AFR_AF,TSPEAR
505056,21:45962974:C>T,NM_144991.2:c.304-9168G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.652,0.0015,1KG_AFR_AF,TSPEAR
505057,21:45963021:G>A,NM_144991.2:c.304-9215C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.209,0.0014,1KG_AMR_AF,TSPEAR
505058,21:45963038:T>C,NM_144991.2:c.304-9232A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.107,\N,\N,TSPEAR
505059,21:45963044:C>G,NM_144991.2:c.304-9238G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.344,\N,\N,TSPEAR
505060,21:45963140:G>A,NM_144991.2:c.304-9334C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,5.215,0.0014,1KG_AMR_AF,TSPEAR
505061,21:45963158:A>T,NM_144991.2:c.304-9352T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.537,0.0014,1KG_AMR_AF,TSPEAR
505062,21:45963262:T>G,NM_144991.2:c.304-9456A>C,\N,\N,2/11,Unknown significance,\N,intron_variant,7.33,\N,\N,TSPEAR
505063,21:45963269:G>A,NM_144991.2:c.304-9463C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.428,0.0014,1KG_AMR_AF,TSPEAR
505064,21:45963282:G>T,NM_144991.2:c.304-9476C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.18,\N,\N,TSPEAR
505065,21:45963287:G>A,NM_144991.2:c.304-9481C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.908,0.002,1KG_EAS_AF,TSPEAR
505066,21:45963318:A>G,NM_144991.2:c.304-9512T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.525,0.0014,1KG_AMR_AF,TSPEAR
505067,21:45963329:C>T,NM_144991.2:c.304-9523G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.756,0.0008,1KG_AFR_AF,TSPEAR
505068,21:45963339:G>C,NM_144991.2:c.304-9533C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.615,\N,\N,TSPEAR
505069,21:45963353:G>A,NM_144991.2:c.304-9547C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.708,\N,\N,TSPEAR
505070,21:45963363:G>A,NM_144991.2:c.304-9557C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.625,0.0014,1KG_AMR_AF,TSPEAR
505071,21:45963376:C>G,NM_144991.2:c.304-9570G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.345,\N,\N,TSPEAR
505072,21:45963400:C>A,NM_144991.2:c.304-9594G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.29,\N,\N,TSPEAR
505073,21:45963418:A>G,NM_144991.2:c.304-9612T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.819,0.0008,1KG_AFR_AF,TSPEAR
505074,21:45963459:C>G,NM_144991.2:c.304-9653G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,5.882,0.001,1KG_EAS_AF,TSPEAR
505075,21:45963460:G>A,NM_144991.2:c.304-9654C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,9.49,0.0045,1KG_AFR_AF,TSPEAR
505076,21:45963463:A>AT,NM_144991.2:c.304-9658dup,\N,\N,2/11,Unknown significance,\N,intron_variant,5.962,\N,\N,TSPEAR
505077,21:45963471:G>T,NM_144991.2:c.304-9665C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,10.3,0.001,1KG_SAS_AF,TSPEAR
505078,21:45963486:T>C,NM_144991.2:c.304-9680A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,12.87,\N,\N,TSPEAR
505079,21:45963499:T>C,NM_144991.2:c.304-9693A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,13.13,0.0008,1KG_AFR_AF,TSPEAR
505080,21:45963506:G>A,NM_144991.2:c.304-9700C>T,\N,\N,2/11,Benign,\N,intron_variant,13.5,0.0197,1KG_AFR_AF,TSPEAR
505081,21:45963507:A>G,NM_144991.2:c.304-9701T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,12.09,\N,\N,TSPEAR
505082,21:45963513:G>A,NM_144991.2:c.304-9707C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,12.44,\N,\N,TSPEAR
505083,21:45963564:G>A,NM_144991.2:c.304-9758C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,5.33,\N,\N,TSPEAR
505084,21:45963572:T>C,NM_144991.2:c.304-9766A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,4.342,0.0008,1KG_AFR_AF,TSPEAR
505085,21:45963578:T>C,NM_144991.2:c.304-9772A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,5.696,\N,\N,TSPEAR
505086,21:45963633:G>A,NM_144991.2:c.304-9827C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.71,0.0023,1KG_AFR_AF,TSPEAR
505087,21:45963653:C>G,NM_144991.2:c.304-9847G>C,\N,\N,2/11,Benign,\N,intron_variant,2.1,0.0119,1KG_EAS_AF,TSPEAR
505088,21:45963662:C>T,NM_144991.2:c.304-9856G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.622,0.0008,1KG_AFR_AF,TSPEAR
505089,21:45963663:G>A,NM_144991.2:c.304-9857C>T,\N,\N,2/11,Benign,\N,intron_variant,0.411,0.007,1KG_EUR_AF,TSPEAR
505090,21:45963673:T>C,NM_144991.2:c.304-9867A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.684,0.0008,1KG_AFR_AF,TSPEAR
505091,21:45963680:G>A,NM_144991.2:c.304-9874C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.307,\N,\N,TSPEAR
505092,21:45963682:G>A,NM_144991.2:c.304-9876C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.074,0.0008,1KG_AFR_AF,TSPEAR
505093,21:45963682:G>T,NM_144991.2:c.304-9876C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.429,\N,\N,TSPEAR
505094,21:45963737:T>C,NM_144991.2:c.304-9931A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.059,\N,\N,TSPEAR
505095,21:45963794:A>G,NM_144991.2:c.304-9988T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,7.561,0.004,1KG_EAS_AF,TSPEAR
505096,21:45963814:A>C,NM_144991.2:c.304-10008T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,5.043,0.002,1KG_EAS_AF,TSPEAR
505097,21:45963908:C>G,NM_144991.2:c.304-10102G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,10.3,\N,\N,TSPEAR
505098,21:45963910:A>G,NM_144991.2:c.304-10104T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,10.86,\N,\N,TSPEAR
505099,21:45963912:C>T,NM_144991.2:c.304-10106G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,11.46,\N,\N,TSPEAR
505100,21:45963913:G>A,NM_144991.2:c.304-10107C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,10.63,\N,\N,TSPEAR
505101,21:45963928:C>T,NM_144991.2:c.304-10122G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,9.779,0.001,1KG_SAS_AF,TSPEAR
505102,21:45963984:T>C,NM_144991.2:c.304-10178A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,2.788,\N,\N,TSPEAR
505103,21:45964015:C>T,NM_144991.2:c.304-10209G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.464,0.0029,1KG_AMR_AF,TSPEAR
505104,21:45964016:G>A,NM_144991.2:c.304-10210C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.268,0.0008,1KG_AFR_AF,TSPEAR
505105,21:45964035:A>T,NM_144991.2:c.304-10229T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.574,\N,\N,TSPEAR
505106,21:45964056:G>C,NM_144991.2:c.304-10250C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.445,\N,\N,TSPEAR
505107,21:45964072:T>C,NM_144991.2:c.304-10266A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,3.228,\N,\N,TSPEAR
505108,21:45964092:G>A,NM_144991.2:c.304-10286C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,7.532,0.0043,1KG_AMR_AF,TSPEAR
505109,21:45964104:C>A,NM_144991.2:c.304-10298G>T,\N,\N,2/11,Benign,\N,intron_variant,8.987,0.0393,1KG_AFR_AF,TSPEAR
505110,21:45964177:T>C,NM_144991.2:c.304-10371A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,3.716,0.002,1KG_EAS_AF,TSPEAR
505111,21:45964182:CA>C,NM_144991.2:c.304-10377del,\N,\N,2/11,Benign,\N,intron_variant,9.111,0.2186,1KG_AFR_AF,TSPEAR
505112,21:45964182:CAA>C,NM_144991.2:c.304-10378_304-10377del,\N,\N,2/11,Benign,\N,intron_variant,8.875,0.4115,1KG_AFR_AF,TSPEAR
505113,21:45964210:C>T,NM_144991.2:c.304-10404G>A,\N,\N,2/11,Benign,\N,intron_variant,0.81,0.3681,1KG_EAS_AF,TSPEAR
505114,21:45964215:G>T,NM_144991.2:c.304-10409C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.92,\N,\N,TSPEAR
505115,21:45964236:A>G,NM_144991.2:c.304-10430T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.36,0.0015,1KG_AFR_AF,TSPEAR
505116,21:45964239:G>T,NM_144991.2:c.304-10433C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.573,\N,\N,TSPEAR
505117,21:45964242:G>C,NM_144991.2:c.304-10436C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.949,\N,\N,TSPEAR
505118,21:45964245:T>G,NM_144991.2:c.304-10439A>C,\N,\N,2/11,Benign,\N,intron_variant,0.468,0.0051,1KG_SAS_AF,TSPEAR
505119,21:45964269:G>C,NM_144991.2:c.304-10463C>G,\N,\N,2/11,Benign,\N,intron_variant,0.615,0.0189,1KG_EUR_AF,TSPEAR
505120,21:45964288:G>A,NM_144991.2:c.304-10482C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.123,\N,\N,TSPEAR
505121,21:45964342:A>C,NM_144991.2:c.304-10536T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,3.614,\N,\N,TSPEAR
505122,21:45964456:A>C,NM_144991.2:c.304-10650T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,6.042,\N,\N,TSPEAR
505123,21:45964458:A>C,NM_144991.2:c.304-10652T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,4.498,0.001,1KG_EAS_AF,TSPEAR
505124,21:45964574:C>T,NM_144991.2:c.304-10768G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.047,0.0008,1KG_AFR_AF,TSPEAR
505125,21:45964580:G>A,NM_144991.2:c.304-10774C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.88,0.0008,1KG_AFR_AF,TSPEAR
505126,21:45964580:G>C,NM_144991.2:c.304-10774C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.684,\N,\N,TSPEAR
505127,21:45964659:C>T,NM_144991.2:c.304-10853G>A,\N,\N,2/11,Benign,\N,intron_variant,0.585,0.0484,1KG_AFR_AF,TSPEAR
505128,21:45964667:A>G,NM_144991.2:c.304-10861T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,3.697,\N,\N,TSPEAR
505129,21:45964669:T>A,NM_144991.2:c.304-10863A>T,\N,\N,2/11,Benign,\N,intron_variant,8.04,0.3661,1KG_EAS_AF,TSPEAR
505130,21:45964697:G>C,NM_144991.2:c.304-10891C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,4.032,\N,\N,TSPEAR
505131,21:45964706:G>A,NM_144991.2:c.304-10900C>T,\N,\N,2/11,Benign,\N,intron_variant,1.978,0.0061,1KG_AFR_AF,TSPEAR
505132,21:45964715:G>C,NM_144991.2:c.304-10909C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,3.995,0.003,1KG_EAS_AF,TSPEAR
505133,21:45964765:A>G,NM_144991.2:c.304-10959T>C,\N,\N,2/11,Benign,\N,intron_variant,4.146,0.0378,1KG_AFR_AF,TSPEAR
505134,21:45964769:A>G,NM_144991.2:c.304-10963T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.646,0.001,1KG_SAS_AF,TSPEAR
505135,21:45964775:A>G,NM_144991.2:c.304-10969T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,4.903,0.001,1KG_EAS_AF,TSPEAR
505136,21:45964779:T>G,NM_144991.2:c.304-10973A>C,\N,\N,2/11,Unknown significance,\N,intron_variant,6.11,\N,\N,TSPEAR
505137,21:45964784:A>G,NM_144991.2:c.304-10978T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,6.087,0.001,1KG_SAS_AF,TSPEAR
505138,21:45964796:A>G,NM_144991.2:c.304-10990T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,9.189,\N,\N,TSPEAR
505139,21:45964819:G>A,NM_144991.2:c.304-11013C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,10.05,\N,\N,TSPEAR
505140,21:45964904:T>A,NM_144991.2:c.304-11098A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,8.02,\N,\N,TSPEAR
505141,21:45964905:TA>T,NM_144991.2:c.304-11100del,\N,\N,2/11,Unknown significance,\N,intron_variant,7.181,\N,\N,TSPEAR
505142,21:45964905:TAAAAA>T,NM_144991.2:c.304-11104_304-11100del,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,0.0038,1KG_AFR_AF,TSPEAR
505143,21:45964918:A>G,NM_144991.2:c.304-11112T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.315,\N,\N,TSPEAR
505144,21:45964919:G>A,NM_144991.2:c.304-11113C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.799,\N,\N,TSPEAR
505145,21:45964929:G>A,NM_144991.2:c.304-11123C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.064,\N,\N,TSPEAR
505146,21:45964930:C>A,NM_144991.2:c.304-11124G>T,\N,\N,2/11,Benign,\N,intron_variant,2.424,0.0068,1KG_AFR_AF,TSPEAR
505147,21:45964930:CGGTGGCTCACGCCTGTAATCCCAGCATTTTGGGAG>C,NM_144991.2:c.304-11159_304-11125del,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
505148,21:45964940:C>T,NM_144991.2:c.304-11134G>A,\N,\N,2/11,Benign,\N,intron_variant,3.282,0.0053,1KG_AFR_AF,TSPEAR
505149,21:45964952:C>T,NM_144991.2:c.304-11146G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.322,\N,\N,TSPEAR
505150,21:45964978:G>C,NM_144991.2:c.304-11172C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.287,0.0015,1KG_AFR_AF,TSPEAR
505151,21:45964998:C>G,NM_144991.2:c.304-11192G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.049,0.001,1KG_SAS_AF,TSPEAR
505152,21:45965023:A>G,NM_144991.2:c.304-11217T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.777,0.001,1KG_EAS_AF,TSPEAR
505153,21:45965035:T>C,NM_144991.2:c.304-11229A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,2.347,\N,\N,TSPEAR
505154,21:45965037:C>T,NM_144991.2:c.304-11231G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.187,\N,\N,TSPEAR
505155,21:45965058:G>A,NM_144991.2:c.304-11252C>T,\N,\N,2/11,Benign,\N,intron_variant,3.116,0.005,1KG_EUR_AF,TSPEAR
505156,21:45965064:G>T,NM_144991.2:c.304-11258C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.544,\N,\N,TSPEAR
505157,21:45965069:C>T,NM_144991.2:c.304-11263G>A,\N,\N,2/11,Benign,\N,intron_variant,2.349,0.0182,1KG_AFR_AF,TSPEAR
505158,21:45965072:C>G,NM_144991.2:c.304-11266G>C,\N,\N,2/11,Benign,\N,intron_variant,1.293,0.1664,1KG_AFR_AF,TSPEAR
505159,21:45965087:G>T,NM_144991.2:c.304-11281C>A,\N,\N,2/11,Benign,\N,intron_variant,3.061,0.0109,1KG_EAS_AF,TSPEAR
505160,21:45965109:G>A,NM_144991.2:c.304-11303C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,4.008,\N,\N,TSPEAR
505161,21:45965117:C>T,NM_144991.2:c.304-11311G>A,\N,\N,2/11,Benign,\N,intron_variant,1.964,0.0119,1KG_EUR_AF,TSPEAR
505162,21:45965149:C>T,NM_144991.2:c.304-11343G>A,\N,\N,2/11,Benign,\N,intron_variant,2.2,0.0257,1KG_AFR_AF,TSPEAR
505163,21:45965156:G>A,NM_144991.2:c.304-11350C>T,\N,\N,2/11,Benign,\N,intron_variant,0.602,0.0106,1KG_AFR_AF,TSPEAR
505164,21:45965166:A>G,NM_144991.2:c.304-11360T>C,\N,\N,2/11,Benign,\N,intron_variant,2.194,0.0542,1KG_SAS_AF,TSPEAR
505165,21:45965185:A>C,NM_144991.2:c.304-11379T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.387,\N,\N,TSPEAR
505166,21:45965186:G>C,NM_144991.2:c.304-11380C>G,\N,\N,2/11,Benign,\N,intron_variant,1.147,0.0159,1KG_AFR_AF,TSPEAR
505167,21:45965198:C>T,NM_144991.2:c.304-11392G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,6.166,0.002,1KG_SAS_AF,TSPEAR
505168,21:45965200:C>CA,NM_144991.2:c.304-11395dup,\N,\N,2/11,Benign,\N,intron_variant,7.082,0.0877,1KG_AFR_AF,TSPEAR
505169,21:45965211:T>A,NM_144991.2:c.304-11405A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,6.953,0.004,1KG_EAS_AF,TSPEAR
505170,21:45965215:T>C,NM_144991.2:c.304-11409A>G,\N,\N,2/11,Benign,\N,intron_variant,4.685,0.0461,1KG_AFR_AF,TSPEAR
505171,21:45965229:A>T,NM_144991.2:c.304-11423T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,6.773,0.001,1KG_EAS_AF|1KG_SAS_AF,TSPEAR
505172,21:45965237:A>G,NM_144991.2:c.304-11431T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,7.174,0.001,1KG_SAS_AF,TSPEAR
505173,21:45965239:G>T,NM_144991.2:c.304-11433C>A,\N,\N,2/11,Benign,\N,intron_variant,5.945,0.0076,1KG_AFR_AF,TSPEAR
505174,21:45965273:C>A,NM_144991.2:c.304-11467G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,8.359,0.0008,1KG_AFR_AF,TSPEAR
505175,21:45965282:C>A,NM_144991.2:c.304-11476G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,8.207,0.0008,1KG_AFR_AF,TSPEAR
505176,21:45965300:C>T,NM_144991.2:c.304-11494G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.348,0.0043,1KG_AMR_AF,TSPEAR
505177,21:45965301:G>A,NM_144991.2:c.304-11495C>T,\N,\N,2/11,Benign,\N,intron_variant,2.694,0.3177,1KG_AFR_AF,TSPEAR
505178,21:45965316:T>C,NM_144991.2:c.304-11510A>G,\N,\N,2/11,Benign,\N,intron_variant,1.123,0.1074,1KG_AFR_AF,TSPEAR
505179,21:45965328:A>C,NM_144991.2:c.304-11522T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.255,0.001,1KG_EAS_AF,TSPEAR
505180,21:45965347:T>C,NM_144991.2:c.304-11541A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,7.732,\N,\N,TSPEAR
505181,21:45965356:G>A,NM_144991.2:c.304-11550C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,10.08,\N,\N,TSPEAR
505182,21:45965359:C>A,NM_144991.2:c.304-11553G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,9.452,0.001,1KG_EUR_AF,TSPEAR
505183,21:45965378:A>G,NM_144991.2:c.304-11572T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,9.983,0.001,1KG_EUR_AF,TSPEAR
505184,21:45965456:T>G,NM_144991.2:c.304-11650A>C,\N,\N,2/11,Benign,\N,intron_variant,7.62,0.008,1KG_EUR_AF,TSPEAR
505185,21:45965512:G>T,NM_144991.2:c.304-11706C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,8.04,0,1KG_ALL_AF|1KG_AFR_AF|1KG_AMR_AF|1KG_EAS_AF|1KG_EUR_AF|1KG_SAS_AF,TSPEAR
505186,21:45965603:A>G,NM_144991.2:c.304-11797T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,7.928,\N,\N,TSPEAR
505187,21:45965610:G>C,NM_144991.2:c.304-11804C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,4.665,\N,\N,TSPEAR
505188,21:45965644:T>C,NM_144991.2:c.304-11838A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,4.326,0.001,1KG_SAS_AF,TSPEAR
505189,21:45965662:T>C,NM_144991.2:c.304-11856A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,4.899,\N,\N,TSPEAR
505190,21:45965681:T>A,NM_144991.2:c.304-11875A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.937,0.0014,1KG_AMR_AF,TSPEAR
505191,21:45965682:A>T,NM_144991.2:c.304-11876T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.933,0.0014,1KG_AMR_AF,TSPEAR
505192,21:45965753:T>C,NM_144991.2:c.304-11947A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.94,0.001,1KG_EAS_AF,TSPEAR
505193,21:45965791:G>C,NM_144991.2:c.304-11985C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.751,0.001,1KG_EUR_AF,TSPEAR
505194,21:45965827:T>A,NM_144991.2:c.304-12021A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,8.139,\N,\N,TSPEAR
505195,21:45965880:A>G,NM_144991.2:c.304-12074T>C,\N,\N,2/11,Benign,\N,intron_variant,7.295,0.0643,1KG_AFR_AF,TSPEAR
505196,21:45965917:T>C,NM_144991.2:c.304-12111A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,5.785,0.0008,1KG_AFR_AF,TSPEAR
505197,21:45965954:A>G,NM_144991.2:c.304-12148T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,5.619,0.003,1KG_AFR_AF,TSPEAR
505198,21:45965992:C>A,NM_144991.2:c.304-12186G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,5.639,0.0038,1KG_AFR_AF,TSPEAR
505199,21:45966025:A>T,NM_144991.2:c.304-12219T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.487,0.001,1KG_EUR_AF,TSPEAR
505200,21:45966051:AC>A,NM_144991.2:c.304-12246del,\N,\N,2/11,Benign,\N,intron_variant,0.694,0.0219,1KG_AFR_AF,TSPEAR
505201,21:45966093:C>T,NM_144991.2:c.304-12287G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.455,0.001,1KG_EAS_AF,TSPEAR
505202,21:45966102:T>C,NM_144991.2:c.304-12296A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.842,0.001,1KG_EUR_AF,TSPEAR
505203,21:45966161:T>G,NM_144991.2:c.304-12355A>C,\N,\N,2/11,Unknown significance,\N,intron_variant,8.957,0.001,1KG_EAS_AF,TSPEAR
505204,21:45966240:C>T,NM_144991.2:c.304-12434G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.552,\N,\N,TSPEAR
505205,21:45966248:C>T,NM_144991.2:c.304-12442G>A,\N,\N,2/11,Benign,\N,intron_variant,6.635,0.0257,1KG_AFR_AF,TSPEAR
505206,21:45966249:G>C,NM_144991.2:c.304-12443C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,2.121,0.0015,1KG_AFR_AF,TSPEAR
505207,21:45966256:T>C,NM_144991.2:c.304-12450A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,6.303,0.001,1KG_SAS_AF,TSPEAR
505208,21:45966266:G>A,NM_144991.2:c.304-12460C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,6.28,0.001,1KG_SAS_AF,TSPEAR
505209,21:45966269:G>A,NM_144991.2:c.304-12463C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,5.143,\N,\N,TSPEAR
505210,21:45966280:C>T,NM_144991.2:c.304-12474G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.006,\N,\N,TSPEAR
505211,21:45966304:G>A,NM_144991.2:c.304-12498C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.517,0.0008,1KG_AFR_AF,TSPEAR
505212,21:45966359:A>T,NM_144991.2:c.304-12553T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.822,\N,\N,TSPEAR
505213,21:45966361:G>A,NM_144991.2:c.304-12555C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.517,\N,\N,TSPEAR
505214,21:45966379:G>A,NM_144991.2:c.304-12573C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.102,\N,\N,TSPEAR
505215,21:45966400:T>C,NM_144991.2:c.304-12594A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.77,0.003,1KG_EAS_AF,TSPEAR
505216,21:45966411:C>T,NM_144991.2:c.304-12605G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.009,0.002,1KG_EUR_AF|1KG_SAS_AF,TSPEAR
505217,21:45966430:C>T,NM_144991.2:c.304-12624G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.499,0.001,1KG_EUR_AF,TSPEAR
505218,21:45966477:C>T,NM_144991.2:c.304-12671G>A,\N,\N,2/11,Benign,\N,intron_variant,2.834,0.056,1KG_AFR_AF,TSPEAR
505219,21:45966482:A>T,NM_144991.2:c.304-12676T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.795,0.0015,1KG_AFR_AF,TSPEAR
505220,21:45966502:C>T,NM_144991.2:c.304-12696G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.121,0.002,1KG_EUR_AF,TSPEAR
505221,21:45966503:G>A,NM_144991.2:c.304-12697C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.125,\N,\N,TSPEAR
505222,21:45966506:C>T,NM_144991.2:c.304-12700G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.197,0.0023,1KG_AFR_AF,TSPEAR
505223,21:45966507:G>A,NM_144991.2:c.304-12701C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.616,\N,\N,TSPEAR
505224,21:45966508:G>T,NM_144991.2:c.304-12702C>A,\N,\N,2/11,Benign,\N,intron_variant,0.096,0.0061,1KG_AFR_AF,TSPEAR
505225,21:45966512:C>G,NM_144991.2:c.304-12706G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,4.372,\N,\N,TSPEAR
505226,21:45966519:AT>A,NM_144991.2:c.304-12714del,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
505227,21:45966578:C>T,NM_144991.2:c.304-12772G>A,\N,\N,2/11,Benign,\N,intron_variant,5.275,0.1021,1KG_AFR_AF,TSPEAR
505228,21:45966579:G>T,NM_144991.2:c.304-12773C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.572,0.0014,1KG_AMR_AF,TSPEAR
505229,21:45966588:C>T,NM_144991.2:c.304-12782G>A,\N,\N,2/11,Benign,\N,intron_variant,7.69,0.1679,1KG_AFR_AF,TSPEAR
505230,21:45966617:A>G,NM_144991.2:c.304-12811T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,11.05,0.0014,1KG_AMR_AF,TSPEAR
505231,21:45966652:C>T,NM_144991.2:c.304-12846G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.077,0.0014,1KG_AMR_AF,TSPEAR
505232,21:45966661:T>C,NM_144991.2:c.304-12855A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.317,0.001,1KG_SAS_AF,TSPEAR
505233,21:45966679:T>TA,NM_144991.2:c.304-12874_304-12873insT,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
505234,21:45966733:T>G,NM_144991.2:c.304-12927A>C,\N,\N,2/11,Benign,\N,intron_variant,3.816,0.4077,1KG_EAS_AF,TSPEAR
505235,21:45966753:T>C,NM_144991.2:c.304-12947A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,5.851,\N,\N,TSPEAR
505236,21:45966830:A>T,NM_144991.2:c.304-13024T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.794,\N,\N,TSPEAR
505237,21:45966844:C>T,NM_144991.2:c.304-13038G>A,\N,\N,2/11,Benign,\N,intron_variant,0.572,0.0477,1KG_AFR_AF,TSPEAR
505238,21:45966884:T>C,NM_144991.2:c.304-13078A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.922,\N,\N,TSPEAR
505239,21:45966885:G>A,NM_144991.2:c.304-13079C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.987,0.001,1KG_EUR_AF,TSPEAR
505240,21:45966955:C>T,NM_144991.2:c.304-13149G>A,\N,\N,2/11,Benign,\N,intron_variant,9.543,0.0477,1KG_AFR_AF,TSPEAR
505241,21:45966957:C>T,NM_144991.2:c.304-13151G>A,\N,\N,2/11,Benign,\N,intron_variant,9.497,0.0182,1KG_AFR_AF,TSPEAR
505242,21:45966966:C>T,NM_144991.2:c.304-13160G>A,\N,\N,2/11,Benign,\N,intron_variant,6.907,0.0793,1KG_AMR_AF,TSPEAR
505243,21:45966982:TA>T,NM_144991.2:c.304-13177del,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
505244,21:45966984:G>C,NM_144991.2:c.304-13178C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.073,\N,\N,TSPEAR
505245,21:45966997:C>T,NM_144991.2:c.304-13191G>A,\N,\N,2/11,Benign,\N,intron_variant,0.249,0.0643,1KG_AFR_AF,TSPEAR
505246,21:45966998:G>A,NM_144991.2:c.304-13192C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.129,0.0008,1KG_AFR_AF,TSPEAR
505247,21:45967014:A>G,NM_144991.2:c.304-13208T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,3.051,0.001,1KG_SAS_AF,TSPEAR
505248,21:45967031:A>G,NM_144991.2:c.304-13225T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,5.954,\N,\N,TSPEAR
505249,21:45967070:T>C,NM_144991.2:c.304-13264A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,9.69,\N,\N,TSPEAR
505250,21:45967104:G>A,NM_144991.2:c.304-13298C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.778,0.0008,1KG_AFR_AF,TSPEAR
505251,21:45967107:T>C,NM_144991.2:c.304-13301A>G,\N,\N,2/11,Benign,\N,intron_variant,0.231,0.1694,1KG_AFR_AF,TSPEAR
505252,21:45967109:G>T,NM_144991.2:c.304-13303C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.339,\N,\N,TSPEAR
505253,21:45967163:C>A,NM_144991.2:c.304-13357G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,10.08,0.0023,1KG_AFR_AF,TSPEAR
505254,21:45967191:T>C,NM_144991.2:c.304-13385A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,8.194,0.0014,1KG_AMR_AF,TSPEAR
505255,21:45967219:T>C,NM_144991.2:c.304-13413A>G,\N,\N,2/11,Benign,\N,intron_variant,2.401,0.0061,1KG_SAS_AF,TSPEAR
505256,21:45967236:C>T,NM_144991.2:c.304-13430G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.123,0.002,1KG_SAS_AF,TSPEAR
505257,21:45967237:G>A,NM_144991.2:c.304-13431C>T,\N,\N,2/11,Benign,\N,intron_variant,0.879,0.0537,1KG_AFR_AF,TSPEAR
505258,21:45967266:G>A,NM_144991.2:c.304-13460C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.403,0.0015,1KG_AFR_AF,TSPEAR
505259,21:45967282:A>G,NM_144991.2:c.304-13476T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.881,\N,\N,TSPEAR
505260,21:45967294:T>C,NM_144991.2:c.304-13488A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.184,\N,\N,TSPEAR
505261,21:45967302:C>G,NM_144991.2:c.304-13496G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.703,\N,\N,TSPEAR
505262,21:45967303:C>A,NM_144991.2:c.304-13497G>T,\N,\N,2/11,Benign,\N,intron_variant,3.143,0.0149,1KG_EUR_AF,TSPEAR
505263,21:45967310:A>G,NM_144991.2:c.304-13504T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.353,0.0014,1KG_AMR_AF,TSPEAR
505264,21:45967330:A>G,NM_144991.2:c.304-13524T>C,\N,\N,2/11,Benign,\N,intron_variant,1.85,0.1619,1KG_AFR_AF,TSPEAR
505265,21:45967331:C>T,NM_144991.2:c.304-13525G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.363,\N,\N,TSPEAR
505266,21:45967359:T>A,NM_144991.2:c.304-13553A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,11.8,0.001,1KG_SAS_AF,TSPEAR
505267,21:45967381:G>T,NM_144991.2:c.304-13575C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,10.05,\N,\N,TSPEAR
505268,21:45967385:C>G,NM_144991.2:c.304-13579G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,10.62,0.001,1KG_EAS_AF,TSPEAR
505269,21:45967386:A>G,NM_144991.2:c.304-13580T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,11.08,0.0008,1KG_AFR_AF,TSPEAR
505270,21:45967450:G>A,NM_144991.2:c.304-13644C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.163,0.002,1KG_SAS_AF,TSPEAR
505271,21:45967472:G>C,NM_144991.2:c.304-13666C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.051,\N,\N,TSPEAR
505272,21:45967507:T>C,NM_144991.2:c.304-13701A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,6.786,\N,\N,TSPEAR
505273,21:45967512:C>T,NM_144991.2:c.304-13706G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,6.453,0.001,1KG_SAS_AF,TSPEAR
505274,21:45967545:C>T,NM_144991.2:c.304-13739G>A,\N,\N,2/11,Benign,\N,intron_variant,5.253,0.1241,1KG_AFR_AF,TSPEAR
505275,21:45967564:G>C,NM_144991.2:c.304-13758C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.264,\N,\N,TSPEAR
505276,21:45967568:T>C,NM_144991.2:c.304-13762A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.724,\N,\N,TSPEAR
505277,21:45967571:T>C,NM_144991.2:c.304-13765A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.997,0.001,1KG_EAS_AF,TSPEAR
505278,21:45967577:G>T,NM_144991.2:c.304-13771C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.509,0.0015,1KG_AFR_AF,TSPEAR
505279,21:45967613:C>G,NM_144991.2:c.304-13807G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.118,\N,\N,TSPEAR
505280,21:45967621:C>T,NM_144991.2:c.304-13815G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.697,0.0045,1KG_AFR_AF,TSPEAR
505281,21:45967673:CACTTCCTGCTTGCACCTTT>C,NM_144991.2:c.304-13886_304-13868del,\N,\N,2/11,Unknown significance,\N,intron_variant,17.51,\N,\N,TSPEAR
505282,21:45967688:C>T,NM_144991.2:c.304-13882G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,18.27,\N,\N,TSPEAR
505283,21:45967692:T>C,NM_144991.2:c.304-13886A>G,\N,\N,2/11,Benign,\N,intron_variant,14.54,0.013,1KG_AMR_AF,TSPEAR
505284,21:45967693:A>C,NM_144991.2:c.304-13887T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,15.71,\N,\N,TSPEAR
505285,21:45967707:C>T,NM_144991.2:c.304-13901G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,16.27,\N,\N,TSPEAR
505286,21:45967712:C>A,NM_144991.2:c.304-13906G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,13.98,\N,\N,TSPEAR
505287,21:45967802:A>C,NM_144991.2:c.304-13996T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.016,0.001,1KG_EAS_AF|1KG_SAS_AF,TSPEAR
505288,21:45967805:C>T,NM_144991.2:c.304-13999G>A,\N,\N,2/11,Benign,\N,intron_variant,0.126,0.0598,1KG_AFR_AF,TSPEAR
505289,21:45967807:T>A,NM_144991.2:c.304-14001A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.147,\N,\N,TSPEAR
505290,21:45967910:C>T,NM_144991.2:c.304-14104G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.296,0.0008,1KG_AFR_AF,TSPEAR
505291,21:45967913:A>G,NM_144991.2:c.304-14107T>C,\N,\N,2/11,Benign,\N,intron_variant,0.422,0.0613,1KG_AFR_AF,TSPEAR
505292,21:45967931:C>T,NM_144991.2:c.304-14125G>A,\N,\N,2/11,Benign,\N,intron_variant,4.522,0.0121,1KG_AFR_AF,TSPEAR
505293,21:45967938:C>T,NM_144991.2:c.304-14132G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,6.402,0.0008,1KG_AFR_AF,TSPEAR
505294,21:45967955:G>A,NM_144991.2:c.304-14149C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,6.04,0.001,1KG_SAS_AF,TSPEAR
505295,21:45967961:T>C,NM_144991.2:c.304-14155A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.205,0.001,1KG_EAS_AF,TSPEAR
505296,21:45967967:G>T,NM_144991.2:c.304-14161C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,5.448,0.0008,1KG_AFR_AF,TSPEAR
505297,21:45968032:G>A,NM_144991.2:c.304-14226C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,9.245,0.001,1KG_EAS_AF|1KG_EUR_AF,TSPEAR
505298,21:45968034:G>A,NM_144991.2:c.304-14228C>T,\N,\N,2/11,Benign,\N,intron_variant,9.538,0.0477,1KG_AFR_AF,TSPEAR
505299,21:45968039:T>C,NM_144991.2:c.304-14233A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,8.314,0.0008,1KG_AFR_AF,TSPEAR
505300,21:45968079:C>T,NM_144991.2:c.304-14273G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.555,\N,\N,TSPEAR
505301,21:45968089:C>T,NM_144991.2:c.304-14283G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,6.536,\N,\N,TSPEAR
505302,21:45968107:C>G,NM_144991.2:c.304-14301G>C,\N,\N,2/11,Benign,\N,intron_variant,0.156,0.1029,1KG_AFR_AF,TSPEAR
505303,21:45968113:T>C,NM_144991.2:c.304-14307A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,4.905,\N,\N,TSPEAR
505304,21:45968124:T>C,NM_144991.2:c.304-14318A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.38,0.0008,1KG_AFR_AF,TSPEAR
505305,21:45968133:A>T,NM_144991.2:c.304-14327T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.035,\N,\N,TSPEAR
505306,21:45968140:C>T,NM_144991.2:c.304-14334G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.313,0.001,1KG_SAS_AF,TSPEAR
505307,21:45968174:G>A,NM_144991.2:c.304-14368C>T,\N,\N,2/11,Benign,\N,intron_variant,0.095,0.0112,1KG_SAS_AF,TSPEAR
505308,21:45968217:G>C,NM_144991.2:c.304-14411C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.049,0.0014,1KG_AMR_AF,TSPEAR
505309,21:45968222:A>G,NM_144991.2:c.304-14416T>C,\N,\N,2/11,Benign,\N,intron_variant,2.694,0.0499,1KG_AFR_AF,TSPEAR
505310,21:45968253:G>A,NM_144991.2:c.304-14447C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.259,0.002,1KG_EAS_AF,TSPEAR
505311,21:45968319:T>C,NM_144991.2:c.304-14513A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.66,\N,\N,TSPEAR
505312,21:45968332:G>C,NM_144991.2:c.304-14526C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.099,\N,\N,TSPEAR
505313,21:45968341:C>T,NM_144991.2:c.304-14535G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.489,0.002,1KG_EUR_AF,TSPEAR
505314,21:45968354:T>C,NM_144991.2:c.304-14548A>G,\N,\N,2/11,Benign,\N,intron_variant,0.762,0.5681,1KG_AFR_AF,TSPEAR
505315,21:45968368:G>T,NM_144991.2:c.304-14562C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.028,\N,\N,TSPEAR
505316,21:45968373:T>C,NM_144991.2:c.304-14567A>G,\N,\N,2/11,Benign,\N,intron_variant,0.273,0.6036,1KG_AFR_AF,TSPEAR
505317,21:45968379:C>T,NM_144991.2:c.304-14573G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.459,0.001,1KG_EUR_AF,TSPEAR
505318,21:45968380:G>A,NM_144991.2:c.304-14574C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.658,0.0045,1KG_AFR_AF,TSPEAR
505319,21:45968391:A>G,NM_144991.2:c.304-14585T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.212,0.001,1KG_EUR_AF,TSPEAR
505320,21:45968408:C>T,NM_144991.2:c.304-14602G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.619,\N,\N,TSPEAR
505321,21:45968423:G>A,NM_144991.2:c.304-14617C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.83,\N,\N,TSPEAR
505322,21:45968428:AGAACACGT>A,NM_144991.2:c.304-14630_304-14623del,\N,\N,2/11,Benign,\N,intron_variant,3.126,0.007,1KG_EUR_AF,TSPEAR
505323,21:45968434:C>T,NM_144991.2:c.304-14628G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.685,\N,\N,TSPEAR
505324,21:45968435:G>A,NM_144991.2:c.304-14629C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.936,\N,\N,TSPEAR
505325,21:45968492:C>T,NM_144991.2:c.304-14686G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.984,0.001,1KG_EUR_AF,TSPEAR
505326,21:45968531:GA>G,NM_144991.2:c.304-14726del,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
505327,21:45968533:C>T,NM_144991.2:c.304-14727G>A,\N,\N,2/11,Benign,\N,intron_variant,4.879,0.0076,1KG_AFR_AF,TSPEAR
505328,21:45968541:G>A,NM_144991.2:c.304-14735C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.127,0.002,1KG_EUR_AF,TSPEAR
505329,21:45968546:C>T,NM_144991.2:c.304-14740G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.953,0.003,1KG_AFR_AF,TSPEAR
505330,21:45968588:C>T,NM_144991.2:c.304-14782G>A,\N,\N,2/11,Benign,\N,intron_variant,4.215,0.0272,1KG_AFR_AF,TSPEAR
505331,21:45968614:C>T,NM_144991.2:c.304-14808G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,6.081,0.001,1KG_SAS_AF,TSPEAR
505332,21:45968617:G>A,NM_144991.2:c.304-14811C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.092,0.0008,1KG_AFR_AF,TSPEAR
505333,21:45968637:G>A,NM_144991.2:c.304-14831C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.82,\N,\N,TSPEAR
505334,21:45968639:C>T,NM_144991.2:c.304-14833G>A,\N,\N,2/11,Benign,\N,intron_variant,2.273,0.0484,1KG_AFR_AF,TSPEAR
505335,21:45968640:G>A,NM_144991.2:c.304-14834C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.989,0.001,1KG_EAS_AF|1KG_SAS_AF,TSPEAR
505336,21:45968716:A>T,NM_144991.2:c.304-14910T>A,\N,\N,2/11,Benign,\N,intron_variant,0.534,0.0099,1KG_EUR_AF,TSPEAR
505337,21:45968716:ACT>A,NM_144991.2:c.304-14912_304-14911del,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
505338,21:45968738:T>G,NM_144991.2:c.304-14932A>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.581,0.0008,1KG_AFR_AF,TSPEAR
505339,21:45968739:T>C,NM_144991.2:c.304-14933A>G,\N,\N,2/11,Benign,\N,intron_variant,0.414,0.323,1KG_AFR_AF,TSPEAR
505340,21:45968783:G>T,NM_144991.2:c.304-14977C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.704,0.001,1KG_SAS_AF,TSPEAR
505341,21:45968810:G>T,NM_144991.2:c.304-15004C>A,\N,\N,2/11,Benign,\N,intron_variant,1.318,0.0115,1KG_AMR_AF,TSPEAR
505342,21:45968836:C>T,NM_144991.2:c.304-15030G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.601,0.0014,1KG_AMR_AF,TSPEAR
505343,21:45968840:C>T,NM_144991.2:c.304-15034G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.396,0.001,1KG_EUR_AF,TSPEAR
505344,21:45968897:C>T,NM_144991.2:c.304-15091G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.593,0.001,1KG_EAS_AF,TSPEAR
505345,21:45968901:C>T,NM_144991.2:c.304-15095G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.606,0.0023,1KG_AFR_AF,TSPEAR
505346,21:45968902:G>A,NM_144991.2:c.304-15096C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.44,0.0043,1KG_AMR_AF,TSPEAR
505347,21:45968902:G>C,NM_144991.2:c.304-15096C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.228,\N,\N,TSPEAR
505348,21:45968908:G>A,NM_144991.2:c.304-15102C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,5.566,\N,\N,TSPEAR
505349,21:45968916:C>T,NM_144991.2:c.304-15110G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,5.245,0.0008,1KG_AFR_AF,TSPEAR
505350,21:45968917:G>A,NM_144991.2:c.304-15111C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,7.252,0.001,1KG_EUR_AF,TSPEAR
505351,21:45968942:G>C,NM_144991.2:c.304-15136C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,8.126,0.0014,1KG_AMR_AF,TSPEAR
505352,21:45968960:C>T,NM_144991.2:c.304-15154G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,7.816,0.001,1KG_EAS_AF,TSPEAR
505353,21:45968998:G>A,NM_144991.2:c.304-15192C>T,\N,\N,2/11,Benign,\N,intron_variant,3.913,0.1014,1KG_AFR_AF,TSPEAR
505354,21:45969002:G>A,NM_144991.2:c.304-15196C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.037,\N,\N,TSPEAR
505355,21:45969008:C>A,NM_144991.2:c.304-15202G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.259,0.001,1KG_EAS_AF,TSPEAR
505356,21:45969024:C>T,NM_144991.2:c.304-15218G>A,\N,\N,2/11,Benign,\N,intron_variant,6.411,0.0603,1KG_SAS_AF,TSPEAR
505357,21:45969025:C>T,NM_144991.2:c.304-15219G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,5.894,0.001,1KG_EAS_AF,TSPEAR
505358,21:45969030:T>C,NM_144991.2:c.304-15224A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,2.434,\N,\N,TSPEAR
505359,21:45969032:G>T,NM_144991.2:c.304-15226C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.25,0.0008,1KG_AFR_AF,TSPEAR
505360,21:45969053:G>T,NM_144991.2:c.304-15247C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.072,\N,\N,TSPEAR
505361,21:45969056:G>T,NM_144991.2:c.304-15250C>A,\N,\N,2/11,Benign,\N,intron_variant,2.699,0.0149,1KG_EUR_AF,TSPEAR
505362,21:45969062:G>A,NM_144991.2:c.304-15256C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,4.92,\N,\N,TSPEAR
505363,21:45969064:C>T,NM_144991.2:c.304-15258G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.422,\N,\N,TSPEAR
505364,21:45969079:G>C,NM_144991.2:c.304-15273C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,2.875,0.0014,1KG_AMR_AF,TSPEAR
505365,21:45969092:T>C,NM_144991.2:c.304-15286A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,6.114,\N,\N,TSPEAR
505366,21:45969107:G>A,NM_144991.2:c.304-15301C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,7.186,0.001,1KG_SAS_AF,TSPEAR
505367,21:45969133:G>A,NM_144991.2:c.304-15327C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.249,0.001,1KG_SAS_AF,TSPEAR
505368,21:45969138:G>T,NM_144991.2:c.304-15332C>A,\N,\N,2/11,Benign,\N,intron_variant,1.468,0.0051,1KG_SAS_AF,TSPEAR
505369,21:45969221:G>T,NM_144991.2:c.304-15415C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.925,\N,\N,TSPEAR
505370,21:45969225:A>G,NM_144991.2:c.304-15419T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,4.664,0.001,1KG_SAS_AF,TSPEAR
505371,21:45969242:C>A,NM_144991.2:c.304-15436G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,7.835,0.0008,1KG_AFR_AF,TSPEAR
505372,21:45969244:A>G,NM_144991.2:c.304-15438T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,3.286,0.001,1KG_EUR_AF,TSPEAR
505373,21:45969264:T>C,NM_144991.2:c.304-15458A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,2.142,0.001,1KG_EAS_AF,TSPEAR
505374,21:45969265:GAAC>G,NM_144991.2:c.304-15462_304-15460del,\N,\N,2/11,Unknown significance,\N,intron_variant,0.799,\N,\N,TSPEAR
505375,21:45969280:C>T,NM_144991.2:c.304-15474G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.666,0.001,1KG_EUR_AF,TSPEAR
505376,21:45969296:C>T,NM_144991.2:c.304-15490G>A,\N,\N,2/11,Benign,\N,intron_variant,5.357,0.0469,1KG_AFR_AF,TSPEAR
505377,21:45969302:G>A,NM_144991.2:c.304-15496C>T,\N,\N,2/11,Benign,\N,intron_variant,0.911,0.0076,1KG_AFR_AF,TSPEAR
505378,21:45969319:C>T,NM_144991.2:c.304-15513G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.532,0.001,1KG_SAS_AF,TSPEAR
505379,21:45969328:C>T,NM_144991.2:c.304-15522G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.11,\N,\N,TSPEAR
505380,21:45969338:A>G,NM_144991.2:c.304-15532T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,3.476,0.003,1KG_EAS_AF,TSPEAR
505381,21:45969343:T>G,NM_144991.2:c.304-15537A>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.397,0.0014,1KG_AMR_AF,TSPEAR
505382,21:45969368:G>A,NM_144991.2:c.304-15562C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.115,\N,\N,TSPEAR
505383,21:45969403:A>T,NM_144991.2:c.304-15597T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.4,0.001,1KG_SAS_AF,TSPEAR
505384,21:45969411:A>G,NM_144991.2:c.304-15605T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,3.045,0.0015,1KG_AFR_AF,TSPEAR
505385,21:45969415:G>A,NM_144991.2:c.304-15609C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.737,0.0023,1KG_AFR_AF,TSPEAR
505386,21:45969422:C>T,NM_144991.2:c.304-15616G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,5.287,\N,\N,TSPEAR
505387,21:45969423:C>T,NM_144991.2:c.304-15617G>A,\N,\N,2/11,Benign,\N,intron_variant,0.467,0.0112,1KG_SAS_AF,TSPEAR
505388,21:45969445:G>A,NM_144991.2:c.304-15639C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.071,0.001,1KG_EAS_AF,TSPEAR
505389,21:45969461:A>C,NM_144991.2:c.304-15655T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.152,\N,\N,TSPEAR
505390,21:45969468:C>T,NM_144991.2:c.304-15662G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.024,0.0008,1KG_AFR_AF,TSPEAR
505391,21:45969475:G>A,NM_144991.2:c.304-15669C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.17,0.002,1KG_SAS_AF,TSPEAR
505392,21:45969479:C>T,NM_144991.2:c.304-15673G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.807,\N,\N,TSPEAR
505393,21:45969480:G>A,NM_144991.2:c.304-15674C>T,\N,\N,2/11,Benign,\N,intron_variant,0.61,0.0348,1KG_AFR_AF,TSPEAR
505394,21:45969483:G>A,NM_144991.2:c.304-15677C>T,\N,\N,2/11,Benign,\N,intron_variant,0.058,0.0325,1KG_AFR_AF,TSPEAR
505395,21:45969488:G>A,NM_144991.2:c.304-15682C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.024,0.0008,1KG_AFR_AF,TSPEAR
505396,21:45969541:C>T,NM_144991.2:c.304-15735G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.402,0.001,1KG_EAS_AF,TSPEAR
505397,21:45969556:T>A,NM_144991.2:c.304-15750A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,6.611,\N,\N,TSPEAR
505398,21:45969588:ACCTGTGCGT>A,NM_144991.2:c.304-15791_304-15783del,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
505399,21:45969596:G>A,NM_144991.2:c.304-15790C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,4.613,0.0015,1KG_AFR_AF,TSPEAR
505400,21:45969601:C>T,NM_144991.2:c.304-15795G>A,\N,\N,2/11,Benign,\N,intron_variant,5.199,0.7025,1KG_SAS_AF,TSPEAR
505401,21:45969607:T>A,NM_144991.2:c.304-15801A>T,\N,\N,2/11,Benign,\N,intron_variant,4.827,0.7065,1KG_SAS_AF,TSPEAR
505402,21:45969653:C>T,NM_144991.2:c.304-15847G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.061,0.001,1KG_EUR_AF,TSPEAR
505403,21:45969667:G>T,NM_144991.2:c.304-15861C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.009,0.001,1KG_EAS_AF,TSPEAR
505404,21:45969683:C>T,NM_144991.2:c.304-15877G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,7.263,0.002,1KG_EUR_AF,TSPEAR
505405,21:45969684:G>A,NM_144991.2:c.304-15878C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.114,0.0015,1KG_AFR_AF,TSPEAR
505406,21:45969692:G>A,NM_144991.2:c.304-15886C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.724,\N,\N,TSPEAR
505407,21:45969694:C>T,NM_144991.2:c.304-15888G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,6.409,\N,\N,TSPEAR
505408,21:45969712:G>A,NM_144991.2:c.304-15906C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,7.361,0.0029,1KG_AMR_AF,TSPEAR
505409,21:45969727:G>A,NM_144991.2:c.304-15921C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.656,0.0045,1KG_AFR_AF,TSPEAR
505410,21:45969727:G>C,NM_144991.2:c.304-15921C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.775,\N,\N,TSPEAR
505411,21:45969728:C>T,NM_144991.2:c.304-15922G>A,\N,\N,2/11,Benign,\N,intron_variant,5.904,0.369,1KG_EAS_AF,TSPEAR
505412,21:45969729:G>A,NM_144991.2:c.304-15923C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.933,\N,\N,TSPEAR
505413,21:45969749:A>T,NM_144991.2:c.304-15943T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.728,\N,\N,TSPEAR
505414,21:45969784:G>A,NM_144991.2:c.304-15978C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.257,0.0014,1KG_AMR_AF,TSPEAR
505415,21:45969805:T>G,NM_144991.2:c.304-15999A>C,\N,\N,2/11,Benign,\N,intron_variant,1.274,0.369,1KG_EAS_AF,TSPEAR
505416,21:45969808:G>A,NM_144991.2:c.304-16002C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.324,0.001,1KG_SAS_AF,TSPEAR
505417,21:45969816:C>G,NM_144991.2:c.304-16010G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.957,0.001,1KG_SAS_AF,TSPEAR
505418,21:45969822:T>A,NM_144991.2:c.304-16016A>T,\N,\N,2/11,Benign,\N,intron_variant,4.909,0.0234,1KG_AFR_AF,TSPEAR
505419,21:45969842:G>A,NM_144991.2:c.304-16036C>T,\N,\N,2/11,Benign,\N,intron_variant,3.399,0.0113,1KG_AFR_AF,TSPEAR
505420,21:45969856:G>A,NM_144991.2:c.304-16050C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.154,\N,\N,TSPEAR
505421,21:45969883:C>T,NM_144991.2:c.304-16077G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,5.415,0.0043,1KG_AMR_AF,TSPEAR
505422,21:45969887:G>C,NM_144991.2:c.304-16081C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.46,\N,\N,TSPEAR
505423,21:45969926:C>T,NM_144991.2:c.304-16120G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.278,0.001,1KG_EUR_AF,TSPEAR
505424,21:45969927:G>C,NM_144991.2:c.304-16121C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.208,0.0008,1KG_AFR_AF,TSPEAR
505425,21:45969929:G>C,NM_144991.2:c.304-16123C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.409,0.003,1KG_AFR_AF,TSPEAR
505426,21:45969970:C>G,NM_144991.2:c.304-16164G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,6.548,0.004,1KG_EAS_AF,TSPEAR
505427,21:45969971:A>G,NM_144991.2:c.304-16165T>C,\N,\N,2/11,Benign,\N,intron_variant,8.348,0.5542,1KG_SAS_AF,TSPEAR
505428,21:45969977:C>G,NM_144991.2:c.304-16171G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.231,\N,\N,TSPEAR
505429,21:45969999:T>C,NM_144991.2:c.304-16193A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.815,\N,\N,TSPEAR
505430,21:45970019:G>T,NM_144991.2:c.304-16213C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.498,0.001,1KG_EUR_AF,TSPEAR
505431,21:45970023:A>G,NM_144991.2:c.304-16217T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,3.933,\N,\N,TSPEAR
505432,21:45970066:G>A,NM_144991.2:c.304-16260C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.299,\N,\N,TSPEAR
505433,21:45970078:G>A,NM_144991.2:c.304-16272C>T,\N,\N,2/11,Benign,\N,intron_variant,0.759,0.681,1KG_SAS_AF,TSPEAR
505434,21:45970078:G>T,NM_144991.2:c.304-16272C>A,\N,\N,2/11,Benign,\N,intron_variant,0.15,0.0522,1KG_AFR_AF,TSPEAR
505435,21:45970084:C>T,NM_144991.2:c.304-16278G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.838,0.001,1KG_EAS_AF,TSPEAR
505436,21:45970093:C>T,NM_144991.2:c.304-16287G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.199,0.0008,1KG_AFR_AF,TSPEAR
505437,21:45970096:G>A,NM_144991.2:c.304-16290C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,4.878,\N,\N,TSPEAR
505438,21:45970117:G>T,NM_144991.2:c.304-16311C>A,\N,\N,2/11,Benign,\N,intron_variant,0.953,0.0227,1KG_AFR_AF,TSPEAR
505439,21:45970120:C>A,NM_144991.2:c.304-16314G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.198,0.0038,1KG_AFR_AF,TSPEAR
505440,21:45970125:C>T,NM_144991.2:c.304-16319G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.543,0.001,1KG_SAS_AF,TSPEAR
505441,21:45970126:G>GA,NM_144991.2:c.304-16321_304-16320insT,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
505442,21:45970129:G>C,NM_144991.2:c.304-16323C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.8,\N,\N,TSPEAR
505443,21:45970129:G>GC,NM_144991.2:c.304-16324dup,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
505444,21:45970199:C>T,NM_144991.2:c.304-16393G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,7.289,\N,\N,TSPEAR
505445,21:45970217:C>G,NM_144991.2:c.304-16411G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.03,0.001,1KG_SAS_AF,TSPEAR
505446,21:45970218:G>A,NM_144991.2:c.304-16412C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.783,\N,\N,TSPEAR
505447,21:45970231:G>A,NM_144991.2:c.304-16425C>T,\N,\N,2/11,Benign,\N,intron_variant,0.785,0.3185,1KG_EAS_AF,TSPEAR
505448,21:45970246:C>T,NM_198693.3:c.*328G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,0.282,0.0014,1KG_AMR_AF,TSPEAR
505449,21:45970247:G>A,NM_198693.3:c.*327C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,0.963,\N,\N,TSPEAR
505450,21:45970252:C>T,NM_198693.3:c.*322G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,1.1,0.0015,1KG_AFR_AF,TSPEAR
505451,21:45970253:G>A,NM_198693.3:c.*321C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,4.222,0.0014,1KG_AMR_AF,TSPEAR
505452,21:45970279:G>C,NM_198693.3:c.*295C>G,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,2.417,\N,\N,TSPEAR
505453,21:45970284:G>A,NM_198693.3:c.*290C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,3.331,\N,\N,TSPEAR
505454,21:45970284:G>T,NM_198693.3:c.*290C>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,1.245,0.0008,1KG_AFR_AF,TSPEAR
505455,21:45970287:C>G,NM_198693.3:c.*287G>C,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,4.398,\N,\N,TSPEAR
505456,21:45970303:A>G,NM_198693.3:c.*271T>C,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,3.227,\N,\N,TSPEAR
505457,21:45970318:A>G,NM_198693.2:c.*256T>C,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,1.954,\N,\N,TSPEAR
505458,21:45970343:G>A,NM_198693.2:c.*231C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,6.202,0.002,1KG_EAS_AF,TSPEAR
505459,21:45970344:C>T,NM_198693.2:c.*230G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,4.138,0.001,1KG_EUR_AF,TSPEAR
505460,21:45970345:G>T,NM_198693.2:c.*229C>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,0.352,\N,\N,TSPEAR
505461,21:45970350:G>GT,NM_198693.2:c.*223dup,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,\N,\N,\N,TSPEAR
505462,21:45970375:C>A,NM_198693.2:c.*199G>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,2.693,\N,\N,TSPEAR
505463,21:45970377:TGAG>T,NM_198693.2:c.*194_*196del,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,\N,\N,\N,TSPEAR
505464,21:45970378:G>A,NM_198693.2:c.*196C>T,\N,1/1,\N,Benign,\N,3_prime_UTR_variant,1.115,0.0182,1KG_AFR_AF,TSPEAR
505465,21:45970384:A>C,NM_198693.2:c.*190T>G,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,2.01,\N,\N,TSPEAR
505466,21:45970395:C>T,NM_198693.2:c.*179G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,4.904,\N,\N,TSPEAR
505467,21:45970399:C>T,NM_198693.2:c.*175G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,2.735,\N,\N,TSPEAR
505468,21:45970400:G>A,NM_198693.2:c.*174C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,2.816,0.001,1KG_SAS_AF,TSPEAR
505469,21:45970406:C>G,NM_198693.2:c.*168G>C,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,3.908,\N,\N,TSPEAR
505470,21:45970407:G>A,NM_198693.2:c.*167C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,4.046,0.0015,1KG_AFR_AF,TSPEAR
505471,21:45970417:A>G,NM_198693.2:c.*157T>C,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,1.723,\N,\N,TSPEAR
505472,21:45970440:AC>A,NM_198693.2:c.*133del,\N,1/1,\N,Benign,\N,3_prime_UTR_variant,2.434,0.0348,1KG_AFR_AF,TSPEAR
505473,21:45970445:G>A,NM_198693.2:c.*129C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,1.17,0.001,1KG_EUR_AF,TSPEAR
505474,21:45970470:T>C,NM_198693.2:c.*104A>G,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,2.247,0.0014,1KG_AMR_AF,TSPEAR
505475,21:45970478:C>T,NM_198693.2:c.*96G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,4.771,0.002,1KG_EAS_AF,TSPEAR
505476,21:45970483:C>T,NM_198693.2:c.*91G>A,\N,1/1,\N,Benign,\N,3_prime_UTR_variant,1.785,0.3651,1KG_EAS_AF,TSPEAR
505477,21:45970485:G>C,NM_198693.2:c.*89C>G,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,0.683,0.0029,1KG_AMR_AF,TSPEAR
505478,21:45970488:C>G,NM_198693.2:c.*86G>C,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,4.515,\N,\N,TSPEAR
505479,21:45970518:C>T,NM_198693.2:c.*56G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,5.136,\N,\N,TSPEAR
505480,21:45970520:A>G,NM_198693.2:c.*54T>C,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,6.477,\N,\N,TSPEAR
505481,21:45970525:T>G,NM_198693.2:c.*49A>C,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,6.903,\N,\N,TSPEAR
505482,21:45970527:G>A,NM_198693.2:c.*47C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,6.749,0.0000314673,EXAC_NFE_AF,TSPEAR
505483,21:45970531:G>A,NM_198693.2:c.*43C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,5.393,0.000174004,EXAC_AMR_AF,TSPEAR
505484,21:45970532:G>A,NM_198693.2:c.*42C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,5.001,\N,\N,TSPEAR
505485,21:45970532:GAGGT>G,NM_198693.2:c.*38_*41del,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,2.469,\N,\N,TSPEAR
505486,21:45970533:A>G,NM_198693.2:c.*41T>C,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,4.449,\N,\N,TSPEAR
505487,21:45970536:T>G,NM_198693.2:c.*38A>C,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,5.063,\N,\N,TSPEAR
505488,21:45970537:G>A,NM_198693.2:c.*37C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,4.22,0.0000313165,EXAC_NFE_AF,TSPEAR
505489,21:45970547:C>G,NM_198693.2:c.*27G>C,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,1.508,0.0015,1KG_AFR_AF,TSPEAR
505490,21:45970548:C>T,NM_198693.2:c.*26G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,5.212,0.0000623636,EXAC_NFE_AF,TSPEAR
505491,21:45970549:C>T,NM_198693.2:c.*25G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,0.947,0.00139058,EXAC_AMR_AF,TSPEAR
505492,21:45970550:G>A,NM_198693.2:c.*24C>T,\N,1/1,\N,Benign,\N,3_prime_UTR_variant,2.429,0.0470135,EXAC_EAS_AF,TSPEAR
505493,21:45970551:G>A,NM_198693.2:c.*23C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,5.789,0.000117841,EVS_EA_AF,TSPEAR
505494,21:45970552:C>G,NM_198693.2:c.*22G>C,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,4.233,0.0000155236,EXAC_NFE_AF,TSPEAR
505495,21:45970552:C>T,NM_198693.2:c.*22G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,5.602,0.0000669703,EXAC_SAS_AF,TSPEAR
505496,21:45970553:T>A,NM_198693.2:c.*21A>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,7.687,0.0000154976,EXAC_NFE_AF,TSPEAR
505497,21:45970556:C>T,NR_130165.1:n.128G>A,\N,2/2,\N,Unknown significance,\N,splice_region_variant&non_coding_transcript_exon_variant,6.882,0.001,1KG_EUR_AF,TSPEAR
505498,21:45970559:TG>T,NR_130165.1:n.127-3del,\N,\N,1/1,Unknown significance,\N,splice_region_variant&intron_variant&non_coding_transcript_variant,5.717,\N,\N,TSPEAR
505499,21:45970567:A>G,NM_198693.2:c.*7T>C,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,0.87,0.00069735,EXAC_EAS_AF,TSPEAR
505500,21:45970568:T>A,NM_198693.2:c.*6A>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,3.699,0.000912409,EVS_AA_AF,TSPEAR
505501,21:45970569:G>A,NM_198693.2:c.*5C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,3.321,0.000117069,EVS_EA_AF,TSPEAR
505502,21:45970570:G>A,NM_198693.2:c.*4C>T,\N,1/1,\N,Benign,\N,3_prime_UTR_variant,4.518,0.0258,1KG_EUR_AF,TSPEAR
505503,21:45970573:A>G,NM_198693.2:c.*1T>C,\N,1/1,\N,Benign,\N,3_prime_UTR_variant,0.809,0.0611691,EXAC_AFR_AF,TSPEAR
505504,21:45970580:G>A,NM_198693.2:c.762C>T,NP_941966.1:p.Ser254=,1/1,\N,Unknown significance,\N,synonymous_variant,5.746,0.000103263,EXAC_AFR_AF,TSPEAR
505505,21:45970581:C>T,NM_198693.2:c.761G>A,NP_941966.1:p.Ser254Asn,1/1,\N,Likely benign,\N,missense_variant,8.884,0.0000150916,EXAC_NFE_AF,TSPEAR
505506,21:45970583:A>G,NM_198693.2:c.759T>C,NP_941966.1:p.Ser253=,1/1,\N,Unknown significance,\N,synonymous_variant,0.232,0.0023,1KG_AFR_AF,TSPEAR
505507,21:45970588:T>C,NM_198693.2:c.754A>G,NP_941966.1:p.Lys252Glu,1/1,\N,Likely benign,\N,missense_variant,0.093,0.000347464,EXAC_EAS_AF,TSPEAR
505508,21:45970589:T>C,NM_198693.2:c.753A>G,NP_941966.1:p.Gln251=,1/1,\N,Unknown significance,\N,synonymous_variant,0.004,0.001,1KG_EUR_AF,TSPEAR
505509,21:45970593:C>A,NM_198693.2:c.749G>T,NP_941966.1:p.Gly250Val,1/1,\N,Likely benign,\N,missense_variant,10.17,0.0000606502,EXAC_SAS_AF,TSPEAR
505510,21:45970594:C>T,NM_198693.2:c.748G>A,NP_941966.1:p.Gly250Ser,1/1,\N,Likely benign,\N,missense_variant,11.21,0.00010227,EXAC_AFR_AF,TSPEAR
505511,21:45970601:A>G,NM_198693.2:c.741T>C,NP_941966.1:p.Phe247=,1/1,\N,Unknown significance,\N,synonymous_variant,0.057,0.000518403,EXAC_AMR_AF,TSPEAR
505512,21:45970604:G>C,NM_198693.2:c.738C>G,NP_941966.1:p.Ser246Arg,1/1,\N,Likely benign,\N,missense_variant,0.003,0.0014,1KG_AMR_AF,TSPEAR
505513,21:45970608:C>T,NM_198693.2:c.734G>A,NP_941966.1:p.Cys245Tyr,1/1,\N,Likely benign,\N,missense_variant,0.899,\N,\N,TSPEAR
505514,21:45970609:A>C,NM_198693.2:c.733T>G,NP_941966.1:p.Cys245Gly,1/1,\N,Unknown significance,\N,missense_variant,12.72,0.000101626,EXAC_AFR_AF,TSPEAR
505515,21:45970609:AG>A,NM_198693.2:c.732del,NP_941966.1:p.Cys245AlafsTer?,1/1,\N,Unknown significance,\N,frameshift_variant,22.5,0.000101626,EXAC_AFR_AF,TSPEAR
505516,21:45970611:G>C,NM_198693.2:c.731C>G,NP_941966.1:p.Ser244Cys,1/1,\N,Likely benign,\N,missense_variant,0.001,\N,\N,TSPEAR
505517,21:45970613:G>A,NM_198693.2:c.729C>T,NP_941966.1:p.Ala243=,1/1,\N,Unknown significance,\N,synonymous_variant,3.696,0.0000605767,EXAC_SAS_AF,TSPEAR
505518,21:45970616:T>C,NM_198693.2:c.726A>G,NP_941966.1:p.Pro242=,1/1,\N,Unknown significance,\N,synonymous_variant,0.007,0.00011566,EXAC_EAS_AF,TSPEAR
505519,21:45970616:TGGGCGGGA>T,NM_198693.2:c.718_725del,NP_941966.1:p.Arg241LeufsTer11,1/1,\N,Unknown significance,\N,frameshift_variant,26.9,0.0000150128,EXAC_NFE_AF,TSPEAR
505520,21:45970616:T>A,NM_198693.2:c.726A>T,NP_941966.1:p.Pro242=,1/1,\N,Unknown significance,\N,synonymous_variant,0.145,0.000453583,EXAC_FIN_AF,TSPEAR
505521,21:45970617:G>A,NM_198693.2:c.725C>T,NP_941966.1:p.Pro242Leu,1/1,\N,Likely benign,\N,missense_variant,5.398,0.000015011,EXAC_NFE_AF,TSPEAR
505522,21:45970620:C>T,NM_198693.2:c.722G>A,NP_941966.1:p.Arg241His,1/1,\N,Likely benign,\N,missense_variant,14.16,0.000172771,EXAC_AMR_AF,TSPEAR
505523,21:45970621:G>A,NM_198693.2:c.721C>T,NP_941966.1:p.Arg241Cys,1/1,\N,Likely benign,\N,missense_variant,22.5,0.000100827,EXAC_AFR_AF,TSPEAR
505524,21:45970621:G>C,NM_198693.2:c.721C>G,NP_941966.1:p.Arg241Gly,1/1,\N,Benign,\N,missense_variant,18.37,0.0407,1KG_EAS_AF,TSPEAR
505525,21:45970623:G>A,NM_198693.2:c.719C>T,NP_941966.1:p.Ser240Phe,1/1,\N,Likely benign,\N,missense_variant,6.76,0.000100462,EXAC_AFR_AF,TSPEAR
505526,21:45970625:G>A,NM_198693.2:c.717C>T,NP_941966.1:p.Cys239=,1/1,\N,Unknown significance,\N,synonymous_variant,4.217,0.00010022,EXAC_AFR_AF,TSPEAR
505527,21:45970629:A>C,NM_198693.2:c.713T>G,NP_941966.1:p.Val238Gly,1/1,\N,Likely benign,\N,missense_variant,12.42,0.001,1KG_SAS_AF,TSPEAR
505528,21:45970630:C>T,NM_198693.2:c.712G>A,NP_941966.1:p.Val238Met,1/1,\N,Likely benign,\N,missense_variant,13.56,0.000232558,EVS_EA_AF,TSPEAR
505529,21:45970631:G>A,NM_198693.2:c.711C>T,NP_941966.1:p.Pro237=,1/1,\N,Unknown significance,\N,synonymous_variant,5.919,0.000423934,EXAC_SAS_AF,TSPEAR
505530,21:45970635:C>T,NM_198693.2:c.707G>A,NP_941966.1:p.Arg236His,1/1,\N,Likely benign,\N,missense_variant,20.6,0.000172771,EXAC_AMR_AF,TSPEAR
505531,21:45970636:G>A,NM_198693.2:c.706C>T,NP_941966.1:p.Arg236Cys,1/1,\N,Unknown significance,\N,missense_variant,23.4,0.0000863707,EXAC_AMR_AF,TSPEAR
505532,21:45970639:A>AGAGGAGGGACACAGAG,NM_198693.2:c.687_702dup,NP_941966.1:p.Cys235LeufsTer25,1/1,\N,Unknown significance,\N,frameshift_variant,26.4,\N,\N,TSPEAR
505533,21:45970640:G>A,NM_198693.2:c.702C>T,NP_941966.1:p.Leu234=,1/1,\N,Unknown significance,\N,synonymous_variant,8.296,0.00011558,EXAC_EAS_AF,TSPEAR
505534,21:45970642:G>A,NM_198693.2:c.700C>T,NP_941966.1:p.Leu234Phe,1/1,\N,Likely benign,\N,missense_variant,17.46,0.000116279,EVS_EA_AF,TSPEAR
505535,21:45970643:G>A,NM_198693.2:c.699C>T,NP_941966.1:p.Leu233=,1/1,\N,Unknown significance,\N,synonymous_variant,4.828,0.0000977899,EXAC_AFR_AF,TSPEAR
505536,21:45970649:C>G,NM_198693.2:c.693G>C,NP_941966.1:p.Val231=,1/1,\N,Unknown significance,\N,synonymous_variant,9.694,0.002,1KG_EUR_AF,TSPEAR
505537,21:45970652:AGAG>A,NM_198693.2:c.687_689del,NP_941966.1:p.Ser230del,1/1,\N,Unknown significance,\N,inframe_deletion,1.489,0.000060562,EXAC_SAS_AF,TSPEAR
505538,21:45970652:A>G,NM_198693.2:c.690T>C,NP_941966.1:p.Ser230=,1/1,\N,Unknown significance,\N,synonymous_variant,0.033,0.000115607,EXAC_EAS_AF,TSPEAR
505539,21:45970653:G>C,NM_198693.2:c.689C>G,NP_941966.1:p.Ser230Cys,1/1,\N,Likely benign,\N,missense_variant,0.001,0.000224813,EXAC_NFE_AF,TSPEAR
505540,21:45970658:G>A,NM_198693.2:c.684C>T,NP_941966.1:p.Ser228=,1/1,\N,Unknown significance,\N,synonymous_variant,4.869,\N,\N,TSPEAR
505541,21:45970659:G>A,NM_198693.2:c.683C>T,NP_941966.1:p.Ser228Phe,1/1,\N,Unknown significance,\N,missense_variant,17.5,\N,\N,TSPEAR
505542,21:45970659:G>T,NM_198693.2:c.683C>A,NP_941966.1:p.Ser228Tyr,1/1,\N,Unknown significance,\N,missense_variant,15.31,\N,\N,TSPEAR
505543,21:45970661:G>A,NM_198693.2:c.681C>T,NP_941966.1:p.Pro227=,1/1,\N,Unknown significance,\N,synonymous_variant,2.291,0.001,1KG_EAS_AF,TSPEAR
505544,21:45970667:G>A,NM_198693.2:c.675C>T,NP_941966.1:p.Cys225=,1/1,\N,Unknown significance,\N,synonymous_variant,2.674,0.0000863707,EXAC_AMR_AF,TSPEAR
505545,21:45970668:C>G,NM_198693.2:c.674G>C,NP_941966.1:p.Cys225Ser,1/1,\N,Unknown significance,\N,missense_variant,17.88,0.0000863707,EXAC_AMR_AF,TSPEAR
505546,21:45970668:C>T,NM_198693.2:c.674G>A,NP_941966.1:p.Cys225Tyr,1/1,\N,Unknown significance,\N,missense_variant,21,0.002,1KG_EAS_AF,TSPEAR
505547,21:45970671:CAGG>C,NM_198693.2:c.668_670del,NP_941966.1:p.Ser223del,1/1,\N,Unknown significance,\N,inframe_deletion,12.22,0.0000965624,EXAC_AFR_AF,TSPEAR
505548,21:45970671:C>A,NM_198693.2:c.671G>T,NP_941966.1:p.Cys224Phe,1/1,\N,Unknown significance,\N,missense_variant,22.6,0.0000863707,EXAC_AMR_AF,TSPEAR
505549,21:45970678:A>T,NM_198693.2:c.664T>A,NP_941966.1:p.Ser222Thr,1/1,\N,Likely benign,\N,missense_variant,0.001,0.00110865,EXAC_OTH_AF,TSPEAR
505550,21:45970681:T>C,NM_198693.2:c.661A>G,NP_941966.1:p.Thr221Ala,1/1,\N,Likely benign,\N,missense_variant,0.034,0.0000605694,EXAC_SAS_AF,TSPEAR
505551,21:45970682:G>A,NM_198693.2:c.660C>T,NP_941966.1:p.Cys220=,1/1,\N,Unknown significance,\N,synonymous_variant,6.877,0.001,1KG_SAS_AF,TSPEAR
505552,21:45970683:C>T,NM_198693.2:c.659G>A,NP_941966.1:p.Cys220Tyr,1/1,\N,Unknown significance,\N,missense_variant,23.4,\N,\N,TSPEAR
505553,21:45970691:T>A,NM_198693.2:c.651A>T,NP_941966.1:p.Pro217=,1/1,\N,Unknown significance,\N,synonymous_variant,2.403,0.000116279,EVS_EA_AF,TSPEAR
505554,21:45970691:T>C,NM_198693.2:c.651A>G,NP_941966.1:p.Pro217=,1/1,\N,Unknown significance,\N,synonymous_variant,0.084,0.0000863707,EXAC_AMR_AF,TSPEAR
505555,21:45970701:C>T,NM_198693.2:c.641G>A,NP_941966.1:p.Ser214Asn,1/1,\N,Unknown significance,\N,missense_variant,15.36,0.0000963206,EXAC_AFR_AF,TSPEAR
505556,21:45970702:T>C,NM_198693.2:c.640A>G,NP_941966.1:p.Ser214Gly,1/1,\N,Likely benign,\N,missense_variant,10.44,0.0000149912,EXAC_NFE_AF,TSPEAR
505557,21:45970708:G>T,NM_198693.2:c.634C>A,NP_941966.1:p.Gln212Lys,1/1,\N,Likely benign,\N,missense_variant,0.122,0.0000149912,EXAC_NFE_AF,TSPEAR
505558,21:45970713:C>T,NM_198693.2:c.629G>A,NP_941966.1:p.Cys210Tyr,1/1,\N,Unknown significance,\N,missense_variant,21.9,0.000181708,EXAC_SAS_AF,TSPEAR
505559,21:45970717:ACGG>A,NM_198693.2:c.622_624del,NP_941966.1:p.Pro208del,1/1,\N,Unknown significance,\N,inframe_deletion,0.241,\N,\N,TSPEAR
505560,21:45970718:C>T,NM_198693.2:c.624G>A,NP_941966.1:p.Pro208=,1/1,\N,Benign,\N,synonymous_variant,9.813,0.368556,EXAC_EAS_AF,TSPEAR
505561,21:45970719:G>A,NM_198693.2:c.623C>T,NP_941966.1:p.Pro208Leu,1/1,\N,Likely benign,\N,missense_variant,3.022,0.000348837,EVS_EA_AF,TSPEAR
505562,21:45970720:G>A,NM_198693.2:c.622C>T,NP_941966.1:p.Pro208Ser,1/1,\N,Likely benign,\N,missense_variant,0.003,0.00011558,EXAC_EAS_AF,TSPEAR
505563,21:45970721:A>T,NM_198693.2:c.621T>A,NP_941966.1:p.Ser207=,1/1,\N,Unknown significance,\N,synonymous_variant,0.038,\N,\N,TSPEAR
505564,21:45970724:G>A,NM_198693.2:c.618C>T,NP_941966.1:p.Ser206=,1/1,\N,Unknown significance,\N,synonymous_variant,2.599,\N,\N,TSPEAR
505565,21:45970727:A>G,NM_198693.2:c.615T>C,NP_941966.1:p.Ala205=,1/1,\N,Unknown significance,\N,synonymous_variant,0.477,0.000209876,EXAC_NFE_AF,TSPEAR
505566,21:45970729:C>A,NM_198693.2:c.613G>T,NP_941966.1:p.Ala205Ser,1/1,\N,Likely benign,\N,missense_variant,2.398,\N,\N,TSPEAR
505567,21:45970731:C>G,NM_198693.2:c.611G>C,NP_941966.1:p.Gly204Ala,1/1,\N,Likely benign,\N,missense_variant,0.001,0.0000149912,EXAC_NFE_AF,TSPEAR
505568,21:45970732:C>T,NM_198693.2:c.610G>A,NP_941966.1:p.Gly204Arg,1/1,\N,Likely benign,\N,missense_variant,6.957,0.0000149912,EXAC_NFE_AF,TSPEAR
505569,21:45970734:G>C,NM_198693.2:c.608C>G,NP_941966.1:p.Ser203Cys,1/1,\N,Likely benign,\N,missense_variant,0.582,\N,\N,TSPEAR
505570,21:45970739:A>G,NM_198693.2:c.603T>C,NP_941966.1:p.Val201=,1/1,\N,Unknown significance,\N,synonymous_variant,0.033,\N,\N,TSPEAR
505571,21:45970740:A>G,NM_198693.2:c.602T>C,NP_941966.1:p.Val201Ala,1/1,\N,Likely benign,\N,missense_variant,0.21,0.00018173,EXAC_SAS_AF,TSPEAR
505572,21:45970742:A>G,NM_198693.2:c.600T>C,NP_941966.1:p.Pro200=,1/1,\N,Unknown significance,\N,synonymous_variant,0.004,\N,\N,TSPEAR
505573,21:45970742:A>T,NM_198693.2:c.600T>A,NP_941966.1:p.Pro200=,1/1,\N,Unknown significance,\N,synonymous_variant,0.002,\N,\N,TSPEAR
505574,21:45970745:T>C,NM_198693.2:c.597A>G,NP_941966.1:p.Val199=,1/1,\N,Unknown significance,\N,synonymous_variant,0.021,0.001,1KG_SAS_AF,TSPEAR
505575,21:45970749:C>T,NM_198693.2:c.593G>A,NP_941966.1:p.Cys198Tyr,1/1,\N,Unknown significance,\N,missense_variant,16.04,\N,\N,TSPEAR
505576,21:45970755:A>G,NM_198693.2:c.587T>C,NP_941966.1:p.Ile196Thr,1/1,\N,Likely benign,\N,missense_variant,0.117,\N,\N,TSPEAR
505577,21:45970756:T>A,NM_198693.2:c.586A>T,NP_941966.1:p.Ile196Phe,1/1,\N,Likely benign,\N,missense_variant,0.107,0.0000500918,EXAC_NFE_AF,TSPEAR
505578,21:45970759:A>G,NM_198693.2:c.583T>C,NP_941966.1:p.Ser195Pro,1/1,\N,Likely benign,\N,missense_variant,0.005,0.0000149921,EXAC_NFE_AF,TSPEAR
505579,21:45970759:ACTTGCAGCAGACAGG>A,NM_198693.2:c.568_582del,NP_941966.1:p.Pro190_Lys194del,1/1,\N,Benign,\N,inframe_deletion,10.29,0.3661,1KG_EAS_AF,TSPEAR
505580,21:45970760:C>T,NM_198693.2:c.582G>A,NP_941966.1:p.Lys194=,1/1,\N,Unknown significance,\N,synonymous_variant,9.235,\N,\N,TSPEAR
505581,21:45970763:GCAGCAGACAGGC>G,NM_198693.2:c.567_578del,NP_941966.1:p.Lys189_Cys193delinsAsn,1/1,\N,Unknown significance,\N,inframe_deletion,10.58,0.000110644,EXAC_AFR_AF,TSPEAR
505582,21:45970764:C>A,NM_198693.2:c.578G>T,NP_941966.1:p.Cys193Phe,1/1,\N,Likely benign,\N,missense_variant,16.87,0.000116279,EVS_EA_AF,TSPEAR
505583,21:45970765:A>G,NM_198693.2:c.577T>C,NP_941966.1:p.Cys193Arg,1/1,\N,Likely benign,\N,missense_variant,9.473,0.000108131,EXAC_AFR_AF,TSPEAR
505584,21:45970766:GCAGACAGGC>G,NM_198693.2:c.567_575del,NP_941966.1:p.Lys189_Cys192delinsAsn,1/1,\N,Unknown significance,\N,inframe_deletion,9.905,0.000154178,EXAC_EAS_AF,TSPEAR
505585,21:45970770:ACAGGC>A,NM_198693.2:c.567_571del,NP_941966.1:p.Lys189AsnfsTer24,1/1,\N,Unknown significance,\N,frameshift_variant,25,0.000223764,EXAC_AFR_AF,TSPEAR
505586,21:45970771:C>T,NM_198693.2:c.571G>A,NP_941966.1:p.Val191Ile,1/1,\N,Likely benign,\N,missense_variant,4.294,\N,\N,TSPEAR
505587,21:45970772:A>G,NM_198693.2:c.570T>C,NP_941966.1:p.Pro190=,1/1,\N,Unknown significance,\N,synonymous_variant,0.009,0.000217912,EXAC_AFR_AF,TSPEAR
505588,21:45970773:G>A,NM_198693.2:c.569C>T,NP_941966.1:p.Pro190Leu,1/1,\N,Unknown significance,\N,missense_variant,18.54,\N,\N,TSPEAR
505589,21:45970774:G>A,NM_198693.2:c.568C>T,NP_941966.1:p.Pro190Ser,1/1,\N,Likely benign,\N,missense_variant,12.78,0.000227066,EXAC_AFR_AF,TSPEAR
505590,21:45970776:TTGC>T,NM_198693.2:c.563_565del,NP_941966.1:p.Cys188_Lys189delinsTer,1/1,\N,Unknown significance,\N,stop_gained&inframe_deletion,26.5,\N,\N,TSPEAR
505591,21:45970776:TTGCAGC>T,NM_198693.2:c.560_565del,NP_941966.1:p.Cys187_Lys189delinsTer,1/1,\N,Unknown significance,\N,stop_gained&inframe_deletion,27,\N,\N,TSPEAR
505592,21:45970776:TTGCAGCAGAC>T,NM_198693.2:c.556_565del,NP_941966.1:p.Val186SerfsTer?,1/1,\N,Unknown significance,\N,frameshift_variant,25.1,\N,\N,TSPEAR
505593,21:45970778:G>A,NM_198693.2:c.564C>T,NP_941966.1:p.Cys188=,1/1,\N,Unknown significance,\N,synonymous_variant,0.436,\N,\N,TSPEAR
505594,21:45970779:C>T,NM_198693.2:c.563G>A,NP_941966.1:p.Cys188Tyr,1/1,\N,Likely benign,\N,missense_variant,15.67,0.000172831,EXAC_AMR_AF,TSPEAR
505595,21:45970781:G>A,NM_198693.2:c.561C>T,NP_941966.1:p.Cys187=,1/1,\N,Unknown significance,\N,synonymous_variant,1.394,\N,\N,TSPEAR
505596,21:45970786:C>T,NM_198693.2:c.556G>A,NP_941966.1:p.Val186Ile,1/1,\N,Likely benign,\N,missense_variant,0.01,0.0000150367,EXAC_NFE_AF,TSPEAR
505597,21:45970787:G>A,NM_198693.2:c.555C>T,NP_941966.1:p.Ser185=,1/1,\N,Unknown significance,\N,synonymous_variant,8.671,0.0000606061,EXAC_SAS_AF,TSPEAR
505598,21:45970789:A>G,NM_198693.2:c.553T>C,NP_941966.1:p.Ser185Pro,1/1,\N,Likely benign,\N,missense_variant,0.002,0.0000606061,EXAC_SAS_AF,TSPEAR
505599,21:45970800:G>T,NM_198693.2:c.542C>A,NP_941966.1:p.Ser181Tyr,1/1,\N,Likely benign,\N,missense_variant,0.652,0.000226963,EVS_AA_AF,TSPEAR
505600,21:45970801:A>C,NM_198693.2:c.541T>G,NP_941966.1:p.Ser181Ala,1/1,\N,Likely benign,\N,missense_variant,0.001,0.001,1KG_EAS_AF,TSPEAR
505601,21:45970811:C>G,NM_198693.2:c.531G>C,NP_941966.1:p.Pro177=,1/1,\N,Unknown significance,\N,synonymous_variant,1.523,0.0000150164,EXAC_NFE_AF,TSPEAR
505602,21:45970811:C>T,NM_198693.2:c.531G>A,NP_941966.1:p.Pro177=,1/1,\N,Unknown significance,\N,synonymous_variant,4.621,0.001,1KG_EAS_AF,TSPEAR
505603,21:45970812:G>A,NM_198693.2:c.530C>T,NP_941966.1:p.Pro177Leu,1/1,\N,Benign,\N,missense_variant,0.03,0.710989,EXAC_SAS_AF,TSPEAR
505604,21:45970821:G>T,NM_198693.2:c.521C>A,NP_941966.1:p.Thr174Asn,1/1,\N,Likely benign,\N,missense_variant,0.754,\N,\N,TSPEAR
505605,21:45970830:G>GC,NM_198693.2:c.511dup,NP_941966.1:p.Ala171GlyfsTer44,1/1,\N,Unknown significance,\N,frameshift_variant,23,\N,\N,TSPEAR
505606,21:45970832:C>T,NM_198693.2:c.510G>A,NP_941966.1:p.Pro170=,1/1,\N,Benign,\N,synonymous_variant,9.163,0.0091,1KG_AFR_AF,TSPEAR
505607,21:45970834:G>A,NM_198693.2:c.508C>T,NP_941966.1:p.Pro170Ser,1/1,\N,Unknown significance,\N,missense_variant,22.3,0.000518314,EXAC_AMR_AF,TSPEAR
505608,21:45970835:C>A,NM_198693.2:c.507G>T,NP_941966.1:p.Gln169His,1/1,\N,Benign,\N,missense_variant,16.66,0.0091,1KG_AFR_AF,TSPEAR
505609,21:45970838:G>T,NM_198693.2:c.504C>A,NP_941966.1:p.Cys168Ter,1/1,\N,Unknown significance,\N,stop_gained,36,0.000151194,EXAC_FIN_AF,TSPEAR
505610,21:45970839:C>A,NM_198693.2:c.503G>T,NP_941966.1:p.Cys168Phe,1/1,\N,Unknown significance,\N,missense_variant,23.6,0.000060562,EXAC_SAS_AF,TSPEAR
505611,21:45970840:A>T,NM_198693.2:c.502T>A,NP_941966.1:p.Cys168Ser,1/1,\N,Unknown significance,\N,missense_variant,21.3,0.000060562,EXAC_SAS_AF,TSPEAR
505612,21:45970850:C>G,NM_198693.2:c.492G>C,NP_941966.1:p.Gln164His,1/1,\N,Unknown significance,\N,missense_variant,19.95,0.000060562,EXAC_SAS_AF,TSPEAR
505613,21:45970888:C>T,NM_198693.2:c.454G>A,NP_941966.1:p.Val152Met,1/1,\N,Likely benign,\N,missense_variant,7.713,0.000431854,EXAC_AMR_AF,TSPEAR
505614,21:45970889:G>A,NM_198693.2:c.453C>T,NP_941966.1:p.Cys151=,1/1,\N,Unknown significance,\N,synonymous_variant,1.749,\N,\N,TSPEAR
505615,21:45970890:C>T,NM_198693.2:c.452G>A,NP_941966.1:p.Cys151Tyr,1/1,\N,Likely benign,\N,missense_variant,8.398,\N,\N,TSPEAR
505616,21:45970895:CACAGCTTTGCAGCAG>C,NM_198693.2:c.432_446del,NP_941966.1:p.Lys147_Cys151del,1/1,\N,Unknown significance,\N,inframe_deletion,11.18,\N,\N,TSPEAR
505617,21:45970898:A>G,NM_198693.2:c.444T>C,NP_941966.1:p.Ala148=,1/1,\N,Unknown significance,\N,synonymous_variant,0.004,0.002,1KG_SAS_AF,TSPEAR
505618,21:45970904:G>A,NM_198693.2:c.438C>T,NP_941966.1:p.Cys146=,1/1,\N,Unknown significance,\N,synonymous_variant,0.635,0.001,1KG_SAS_AF,TSPEAR
505619,21:45970910:G>C,NM_198693.2:c.432C>G,NP_941966.1:p.Val144=,1/1,\N,Unknown significance,\N,synonymous_variant,0.175,\N,\N,TSPEAR
505620,21:45970913:A>T,NM_198693.2:c.429T>A,NP_941966.1:p.Pro143=,1/1,\N,Unknown significance,\N,synonymous_variant,0.002,0.0000149835,EXAC_NFE_AF,TSPEAR
505621,21:45970920:C>T,NM_198693.2:c.422G>A,NP_941966.1:p.Arg141His,1/1,\N,Benign,\N,missense_variant,21.8,0.0447536,EXAC_FIN_AF,TSPEAR
505622,21:45970921:G>A,NM_198693.2:c.421C>T,NP_941966.1:p.Arg141Cys,1/1,\N,Likely benign,\N,missense_variant,2.874,0.002,1KG_EUR_AF,TSPEAR
505623,21:45970922:G>A,NM_198693.2:c.420C>T,NP_941966.1:p.Cys140=,1/1,\N,Unknown significance,\N,synonymous_variant,0.849,0.0000863707,EXAC_AMR_AF,TSPEAR
505624,21:45970927:A>G,NM_198693.2:c.415T>C,NP_941966.1:p.Ser139Pro,1/1,\N,Likely benign,\N,missense_variant,0.086,\N,\N,TSPEAR
505625,21:45970936:A>T,NM_198693.2:c.406T>A,NP_941966.1:p.Cys136Ser,1/1,\N,Unknown significance,\N,missense_variant,3.537,0.001,1KG_EAS_AF,TSPEAR
505626,21:45970940:G>A,NM_198693.2:c.402C>T,NP_941966.1:p.Ser134=,1/1,\N,Unknown significance,\N,synonymous_variant,2.999,0.0000149835,EXAC_NFE_AF,TSPEAR
505627,21:45970952:G>A,NM_198693.2:c.390C>T,NP_941966.1:p.Cys130=,1/1,\N,Unknown significance,\N,synonymous_variant,1.752,0.0000149835,EXAC_NFE_AF,TSPEAR
505628,21:45970960:G>C,NM_198693.2:c.382C>G,NP_941966.1:p.Pro128Ala,1/1,\N,Likely benign,\N,missense_variant,9.432,0.000116279,EVS_EA_AF,TSPEAR
505629,21:45970963:G>A,NM_198693.2:c.379C>T,NP_941966.1:p.Gln127Ter,1/1,\N,Unknown significance,\N,stop_gained,33,0.0000150725,EXAC_NFE_AF,TSPEAR
505630,21:45970966:A>C,NM_198693.2:c.376T>G,NP_941966.1:p.Cys126Gly,1/1,\N,Unknown significance,\N,missense_variant,16.37,0.0000150725,EXAC_NFE_AF,TSPEAR
505631,21:45970980:C>T,NM_198693.2:c.362G>A,NP_941966.1:p.Cys121Tyr,1/1,\N,Unknown significance,\N,missense_variant,22.8,0.001,1KG_SAS_AF,TSPEAR
505632,21:45970984:A>G,NM_198693.2:c.358T>C,NP_941966.1:p.Cys120Arg,1/1,\N,Unknown significance,\N,missense_variant,21.8,0.001,1KG_SAS_AF,TSPEAR
505633,21:45970985:T>C,NM_198693.2:c.357A>G,NP_941966.1:p.Ser119=,1/1,\N,Unknown significance,\N,synonymous_variant,0.291,0.0000150871,EXAC_NFE_AF,TSPEAR
505634,21:45970989:GAA>G,NM_198693.2:c.351_352del,NP_941966.1:p.Ser118PhefsTer7,1/1,\N,Unknown significance,\N,frameshift_variant,19.42,\N,\N,TSPEAR
505635,21:45970992:G>T,NM_198693.2:c.350C>A,NP_941966.1:p.Ala117Asp,1/1,\N,Likely benign,\N,missense_variant,3.064,0.0000868056,EXAC_AMR_AF,TSPEAR
505636,21:45970993:C>G,NM_198693.2:c.349G>C,NP_941966.1:p.Ala117Pro,1/1,\N,Benign,\N,missense_variant,0.093,0.3651,1KG_EAS_AF,TSPEAR
505637,21:45970998:C>G,NM_198693.2:c.344G>C,NP_941966.1:p.Cys115Ser,1/1,\N,Likely benign,\N,missense_variant,0.157,\N,\N,TSPEAR
505638,21:45971002:A>C,NM_198693.2:c.340T>G,NP_941966.1:p.Cys114Gly,1/1,\N,Unknown significance,\N,missense_variant,10.37,0.000060746,EXAC_SAS_AF,TSPEAR
505639,21:45971004:A>G,NM_198693.2:c.338T>C,NP_941966.1:p.Val113Ala,1/1,\N,Likely benign,\N,missense_variant,0.156,0.000060746,EXAC_SAS_AF,TSPEAR
505640,21:45971005:C>A,NM_198693.2:c.337G>T,NP_941966.1:p.Val113Phe,1/1,\N,Likely benign,\N,missense_variant,14.39,0.000232829,EXAC_EAS_AF,TSPEAR
505641,21:45971005:C>T,NM_198693.2:c.337G>A,NP_941966.1:p.Val113Ile,1/1,\N,Likely benign,\N,missense_variant,4.572,0.0008,1KG_AFR_AF,TSPEAR
505642,21:45971006:G>A,NM_198693.2:c.336C>T,NP_941966.1:p.Pro112=,1/1,\N,Unknown significance,\N,synonymous_variant,6.042,0.0000867905,EXAC_AMR_AF,TSPEAR
505643,21:45971008:G>A,NM_198693.2:c.334C>T,NP_941966.1:p.Pro112Ser,1/1,\N,Unknown significance,\N,missense_variant,6.976,\N,\N,TSPEAR
505644,21:45971013:C>G,NM_198693.2:c.329G>C,NP_941966.1:p.Cys110Ser,1/1,\N,Unknown significance,\N,missense_variant,2.982,0.0000867905,EXAC_AMR_AF,TSPEAR
505645,21:45971018:C>G,NM_198693.2:c.324G>C,NP_941966.1:p.Val108=,1/1,\N,Benign,\N,synonymous_variant,0.551,0.3681,1KG_EAS_AF,TSPEAR
505646,21:45971020:C>T,NM_198693.2:c.322G>A,NP_941966.1:p.Val108Met,1/1,\N,Unknown significance,\N,missense_variant,14.07,0.0000607681,EXAC_SAS_AF,TSPEAR
505647,21:45971021:A>G,NM_198693.2:c.321T>C,NP_941966.1:p.Pro107=,1/1,\N,Unknown significance,\N,synonymous_variant,0.003,0.0000607681,EXAC_SAS_AF,TSPEAR
505648,21:45971023:G>A,NM_198693.2:c.319C>T,NP_941966.1:p.Pro107Ser,1/1,\N,Likely benign,\N,missense_variant,0.561,0.000465441,EXAC_EAS_AF,TSPEAR
505649,21:45971023:G>T,NM_198693.2:c.319C>A,NP_941966.1:p.Pro107Thr,1/1,\N,Benign,\N,missense_variant,6.329,0.369,1KG_EAS_AF,TSPEAR
505650,21:45971026:TGCAGCAGACGGGCAC>T,NM_198693.2:c.301_315del,NP_941966.1:p.Val101_Cys105del,1/1,\N,Unknown significance,\N,inframe_deletion,\N,\N,\N,TSPEAR
505651,21:45971035:C>T,NM_198693.2:c.307G>A,NP_941966.1:p.Val103Ile,1/1,\N,Likely benign,\N,missense_variant,6.971,0.000182282,EXAC_SAS_AF,TSPEAR
505652,21:45971036:G>A,NM_198693.2:c.306C>T,NP_941966.1:p.Pro102=,1/1,\N,Unknown significance,\N,synonymous_variant,8.223,0.001,1KG_EUR_AF,TSPEAR
505653,21:45971041:C>T,NM_198693.2:c.301G>A,NP_941966.1:p.Val101Met,1/1,\N,Likely benign,\N,missense_variant,13.66,0.000495933,EXAC_AFR_AF,TSPEAR
505654,21:45971042:G>A,NM_198693.2:c.300C>T,NP_941966.1:p.Cys100=,1/1,\N,Unknown significance,\N,synonymous_variant,6.629,0.000105779,EXAC_NFE_AF,TSPEAR
505655,21:45971042:G>C,NM_198693.2:c.300C>G,NP_941966.1:p.Cys100Trp,1/1,\N,Benign,\N,missense_variant,13.76,0.00629664,EXAC_EAS_AF,TSPEAR
505656,21:45971050:C>A,NM_198693.2:c.292G>T,NP_941966.1:p.Ala98Ser,1/1,\N,Likely benign,\N,missense_variant,0.997,0.001,1KG_SAS_AF,TSPEAR
505657,21:45971050:C>T,NM_198693.2:c.292G>A,NP_941966.1:p.Ala98Thr,1/1,\N,Likely benign,\N,missense_variant,7.871,0.0000869263,EXAC_AMR_AF,TSPEAR
505658,21:45971061:G>A,NM_198693.2:c.281C>T,NP_941966.1:p.Pro94Leu,1/1,\N,Unknown significance,\N,missense_variant,19.52,0.0000151304,EXAC_NFE_AF,TSPEAR
505659,21:45971062:G>A,NM_198693.2:c.280C>T,NP_941966.1:p.Pro94Ser,1/1,\N,Benign,\N,missense_variant,9.383,0.005,1KG_EAS_AF,TSPEAR
505660,21:45971064:G>A,NM_198693.2:c.278C>T,NP_941966.1:p.Ser93Phe,1/1,\N,Unknown significance,\N,missense_variant,21.5,0.0000451508,EXAC_NFE_AF,TSPEAR
505661,21:45971066:G>A,NM_198693.2:c.276C>T,NP_941966.1:p.Ser92=,1/1,\N,Unknown significance,\N,synonymous_variant,6.679,\N,\N,TSPEAR
505662,21:45971069:G>A,NM_198693.2:c.273C>T,NP_941966.1:p.Thr91=,1/1,\N,Unknown significance,\N,synonymous_variant,7.861,\N,\N,TSPEAR
505663,21:45971069:G>T,NM_198693.2:c.273C>A,NP_941966.1:p.Thr91=,1/1,\N,Unknown significance,\N,synonymous_variant,6.263,\N,\N,TSPEAR
505664,21:45971070:G>A,NM_198693.2:c.272C>T,NP_941966.1:p.Thr91Ile,1/1,\N,Likely benign,\N,missense_variant,11.34,0.0000867002,EXAC_AMR_AF,TSPEAR
505665,21:45971079:G>T,NM_198693.2:c.263C>A,NP_941966.1:p.Ala88Asp,1/1,\N,Benign,\N,missense_variant,22.3,0.0139,1KG_EAS_AF,TSPEAR
505666,21:45971081:C>T,NM_198693.2:c.261G>A,NP_941966.1:p.Pro87=,1/1,\N,Unknown significance,\N,synonymous_variant,17.37,0.00223214,EXAC_OTH_AF,TSPEAR
505667,21:45971082:G>A,NM_198693.2:c.260C>T,NP_941966.1:p.Pro87Leu,1/1,\N,Unknown significance,\N,missense_variant,22.9,\N,\N,TSPEAR
505668,21:45971083:G>A,NM_198693.2:c.259C>T,NP_941966.1:p.Pro87Ser,1/1,\N,Likely benign,\N,missense_variant,16.22,\N,\N,TSPEAR
505669,21:45971087:G>T,NM_198693.2:c.255C>A,NP_941966.1:p.Cys85Ter,1/1,\N,Unknown significance,\N,stop_gained,37,\N,\N,TSPEAR
505670,21:45971088:C>T,NM_198693.2:c.254G>A,NP_941966.1:p.Cys85Tyr,1/1,\N,Unknown significance,\N,missense_variant,23.6,\N,\N,TSPEAR
505671,21:45971089:AG>A,NM_198693.2:c.252del,NP_941966.1:p.Cys85AlafsTer?,1/1,\N,Unknown significance,\N,frameshift_variant,27.8,\N,\N,TSPEAR
505672,21:45971095:A>G,NM_198693.2:c.247T>C,NP_941966.1:p.Ser83Pro,1/1,\N,Unknown significance,\N,missense_variant,23.1,\N,\N,TSPEAR
505673,21:45971106:C>A,NM_198693.2:c.236G>T,NP_941966.1:p.Cys79Phe,1/1,\N,Unknown significance,\N,missense_variant,23.1,0.0000608125,EXAC_SAS_AF,TSPEAR
505674,21:45971106:C>T,NM_198693.2:c.236G>A,NP_941966.1:p.Cys79Tyr,1/1,\N,Unknown significance,\N,missense_variant,22,0.0000151277,EXAC_NFE_AF,TSPEAR
505675,21:45971108:C>T,NM_198693.2:c.234G>A,NP_941966.1:p.Ser78=,1/1,\N,Unknown significance,\N,synonymous_variant,11.84,\N,\N,TSPEAR
505676,21:45971109:G>A,NM_198693.2:c.233C>T,NP_941966.1:p.Ser78Leu,1/1,\N,Likely benign,\N,missense_variant,17.66,\N,\N,TSPEAR
505677,21:45971114:C>T,NM_198693.2:c.228G>A,NP_941966.1:p.Thr76=,1/1,\N,Benign,\N,synonymous_variant,7.907,0.022243,EXAC_EAS_AF,TSPEAR
505678,21:45971115:G>A,NM_198693.2:c.227C>T,NP_941966.1:p.Thr76Met,1/1,\N,Likely benign,\N,missense_variant,6.454,\N,\N,TSPEAR
505679,21:45971122:A>C,NM_198693.2:c.220T>G,NP_941966.1:p.Ser74Ala,1/1,\N,Unknown significance,\N,missense_variant,14.08,0.000227169,EVS_AA_AF,TSPEAR
505680,21:45971127:G>T,NM_198693.2:c.215C>A,NP_941966.1:p.Thr72Asn,1/1,\N,Unknown significance,\N,missense_variant,12.11,\N,\N,TSPEAR
505681,21:45971141:G>T,NM_198693.2:c.201C>A,NP_941966.1:p.Cys67Ter,1/1,\N,Unknown significance,\N,stop_gained,35,0.00238243,EXAC_AFR_AF,TSPEAR
505682,21:45971146:C>G,NM_198693.2:c.196G>C,NP_941966.1:p.Ala66Pro,1/1,\N,Likely benign,\N,missense_variant,15.54,0.00112108,EXAC_OTH_AF,TSPEAR
505683,21:45971146:C>T,NM_198693.2:c.196G>A,NP_941966.1:p.Ala66Thr,1/1,\N,Likely benign,\N,missense_variant,16.11,0.000347403,EXAC_AMR_AF,TSPEAR
505684,21:45971147:G>A,NM_198693.2:c.195C>T,NP_941966.1:p.Ser65=,1/1,\N,Unknown significance,\N,synonymous_variant,3.494,0.0000908898,EXAC_NFE_AF,TSPEAR
505685,21:45971147:G>T,NM_198693.2:c.195C>A,NP_941966.1:p.Ser65Arg,1/1,\N,Unknown significance,\N,missense_variant,21.5,0.0000868508,EXAC_AMR_AF,TSPEAR
505686,21:45971152:G>A,NM_198693.2:c.190C>T,NP_941966.1:p.Pro64Ser,1/1,\N,Likely benign,\N,missense_variant,8.446,\N,\N,TSPEAR
505687,21:45971157:C>A,NM_198693.2:c.185G>T,NP_941966.1:p.Cys62Phe,1/1,\N,Unknown significance,\N,missense_variant,23.5,0.000425428,EXAC_SAS_AF,TSPEAR
505688,21:45971160:G>C,NM_198693.2:c.182C>G,NP_941966.1:p.Ala61Gly,1/1,\N,Unknown significance,\N,missense_variant,22.5,0.0000607755,EXAC_SAS_AF,TSPEAR
505689,21:45971162:C>T,NM_198693.2:c.180G>A,NP_941966.1:p.Ala60=,1/1,\N,Unknown significance,\N,synonymous_variant,9.586,\N,\N,TSPEAR
505690,21:45971163:G>A,NM_198693.2:c.179C>T,NP_941966.1:p.Ala60Val,1/1,\N,Likely benign,\N,missense_variant,0.323,0.000121521,EXAC_SAS_AF,TSPEAR
505691,21:45971163:G>T,NM_198693.2:c.179C>A,NP_941966.1:p.Ala60Glu,1/1,\N,Likely benign,\N,missense_variant,13.83,0.001,1KG_EAS_AF,TSPEAR
505692,21:45971164:C>T,NM_198693.2:c.178G>A,NP_941966.1:p.Ala60Thr,1/1,\N,Likely benign,\N,missense_variant,3.322,\N,\N,TSPEAR
505693,21:45971165:C>A,NM_198693.2:c.177G>T,NP_941966.1:p.Gln59His,1/1,\N,Unknown significance,\N,missense_variant,22.8,0.0000607755,EXAC_SAS_AF,TSPEAR
505694,21:45971169:C>G,NM_198693.2:c.173G>C,NP_941966.1:p.Cys58Ser,1/1,\N,Unknown significance,\N,missense_variant,17.99,0.0000151943,EXAC_NFE_AF,TSPEAR
505695,21:45971176:G>A,NM_198693.2:c.166C>T,NP_941966.1:p.Pro56Ser,1/1,\N,Unknown significance,\N,missense_variant,22.2,0.001,1KG_SAS_AF,TSPEAR
505696,21:45971176:G>T,NM_198693.2:c.166C>A,NP_941966.1:p.Pro56Thr,1/1,\N,Unknown significance,\N,missense_variant,23.4,0.000015192,EXAC_NFE_AF,TSPEAR
505697,21:45971177:G>T,NM_198693.2:c.165C>A,NP_941966.1:p.Ser55Arg,1/1,\N,Unknown significance,\N,missense_variant,24.6,0.0000303841,EXAC_NFE_AF,TSPEAR
505698,21:45971181:G>T,NM_198693.2:c.161C>A,NP_941966.1:p.Ser54Tyr,1/1,\N,Unknown significance,\N,missense_variant,24,0.0000151888,EXAC_NFE_AF,TSPEAR
505699,21:45971183:C>G,NM_198693.2:c.159G>C,NP_941966.1:p.Val53=,1/1,\N,Unknown significance,\N,synonymous_variant,10.74,0.001,1KG_SAS_AF,TSPEAR
505700,21:45971187:C>G,NM_198693.2:c.155G>C,NP_941966.1:p.Cys52Ser,1/1,\N,Unknown significance,\N,missense_variant,21,0.000106267,EXAC_NFE_AF,TSPEAR
505701,21:45971188:A>G,NM_198693.2:c.154T>C,NP_941966.1:p.Cys52Arg,1/1,\N,Unknown significance,\N,missense_variant,22.7,0.0000868206,EXAC_AMR_AF,TSPEAR
505702,21:45971201:G>C,NM_198693.2:c.141C>G,NP_941966.1:p.Cys47Trp,1/1,\N,Unknown significance,\N,missense_variant,24.6,0.0000151543,EXAC_NFE_AF,TSPEAR
505703,21:45971205:A>C,NM_198693.2:c.137T>G,NP_941966.1:p.Val46Gly,1/1,\N,Unknown significance,\N,missense_variant,23.4,0.0000151469,EXAC_NFE_AF,TSPEAR
505704,21:45971207:C>T,NM_198693.2:c.135G>A,NP_941966.1:p.Leu45=,1/1,\N,Unknown significance,\N,synonymous_variant,11.47,0.000173671,EXAC_AMR_AF,TSPEAR
505705,21:45971211:G>C,NM_198693.2:c.131C>G,NP_941966.1:p.Thr44Ser,1/1,\N,Likely benign,\N,missense_variant,19.33,\N,\N,TSPEAR
505706,21:45971212:T>C,NM_198693.2:c.130A>G,NP_941966.1:p.Thr44Ala,1/1,\N,Unknown significance,\N,missense_variant,13.6,0.0000607755,EXAC_SAS_AF,TSPEAR
505707,21:45971213:C>T,NM_198693.2:c.129G>A,NP_941966.1:p.Leu43=,1/1,\N,Unknown significance,\N,synonymous_variant,10.75,0.00362065,EXAC_EAS_AF,TSPEAR
505708,21:45971215:G>A,NM_198693.2:c.127C>T,NP_941966.1:p.Leu43=,1/1,\N,Unknown significance,\N,synonymous_variant,6.473,0.00111359,EXAC_OTH_AF,TSPEAR
505709,21:45971217:C>G,NM_198693.2:c.125G>C,NP_941966.1:p.Cys42Ser,1/1,\N,Likely benign,\N,missense_variant,23.1,\N,\N,TSPEAR
505710,21:45971218:A>T,NM_198693.2:c.124T>A,NP_941966.1:p.Cys42Ser,1/1,\N,Unknown significance,\N,missense_variant,22.8,0.00111359,EXAC_OTH_AF,TSPEAR
505711,21:45971221:G>C,NM_198693.2:c.121C>G,NP_941966.1:p.Pro41Ala,1/1,\N,Likely benign,\N,missense_variant,0.055,0.000116333,EVS_EA_AF,TSPEAR
505712,21:45971222:G>A,NM_198693.2:c.120C>T,NP_941966.1:p.Ala40=,1/1,\N,Unknown significance,\N,synonymous_variant,6.119,0.000260371,EXAC_AMR_AF,TSPEAR
505713,21:45971225:T>C,NM_198693.2:c.117A>G,NP_941966.1:p.Pro39=,1/1,\N,Benign,\N,synonymous_variant,0.111,0.0408,1KG_AFR_AF,TSPEAR
505714,21:45971229:G>T,NM_198693.2:c.113C>A,NP_941966.1:p.Ala38Asp,1/1,\N,Likely benign,\N,missense_variant,17.76,0.00128325,EXAC_EAS_AF,TSPEAR
505715,21:45971231:A>G,NM_198693.2:c.111T>C,NP_941966.1:p.Cys37=,1/1,\N,Unknown significance,\N,synonymous_variant,0.007,0.000243072,EXAC_SAS_AF,TSPEAR
505716,21:45971239:T>C,NM_198693.2:c.103A>G,NP_941966.1:p.Ser35Gly,1/1,\N,Unknown significance,\N,missense_variant,22.8,0.0000150639,EXAC_NFE_AF,TSPEAR
505717,21:45971241:G>C,NM_198693.2:c.101C>G,NP_941966.1:p.Pro34Arg,1/1,\N,Unknown significance,\N,missense_variant,23.5,0.001,1KG_SAS_AF,TSPEAR
505718,21:45971244:GTGC>G,NM_198693.2:c.95_97del,NP_941966.1:p.Gly32_Thr33delinsAla,1/1,\N,Unknown significance,\N,inframe_deletion,11.75,0.0000150539,EXAC_NFE_AF,TSPEAR
505719,21:45971244:G>T,NM_198693.2:c.98C>A,NP_941966.1:p.Thr33Asn,1/1,\N,Likely benign,\N,missense_variant,9.489,0.0000752695,EXAC_NFE_AF,TSPEAR
505720,21:45971248:C>T,NM_198693.2:c.94G>A,NP_941966.1:p.Gly32Ser,1/1,\N,Unknown significance,\N,missense_variant,21.9,0.000232558,EVS_EA_AF,TSPEAR
505721,21:45971249:GCAGGGGAGCTCA>G,NR_130165.1:n.126+2_126+13del,\N,\N,1/1,Unknown significance,\N,splice_donor_variant&intron_variant&non_coding_transcript_variant,12.69,0.0000150435,EXAC_NFE_AF,TSPEAR
505722,21:45971249:G>A,NM_198693.2:c.93C>T,NP_941966.1:p.Cys31=,1/1,\N,Unknown significance,\N,synonymous_variant,6.622,0.0000865951,EXAC_AMR_AF,TSPEAR
505723,21:45971252:G>A,NM_198693.2:c.90C>T,NP_941966.1:p.Pro30=,1/1,\N,Benign,\N,synonymous_variant,2.185,0.00742721,EXAC_AFR_AF,TSPEAR
505724,21:45971256:A>G,NM_198693.2:c.86T>C,NP_941966.1:p.Leu29Pro,1/1,\N,Likely benign,\N,missense_variant,1.353,0.0000985416,EXAC_AFR_AF,TSPEAR
505725,21:45971258:C>G,NM_198693.2:c.84G>C,NP_941966.1:p.Glu28Asp,1/1,\N,Unknown significance,\N,missense_variant,23.5,0.000015024,EXAC_NFE_AF,TSPEAR
505726,21:45971269:T>C,NM_198693.2:c.73A>G,NP_941966.1:p.Ser25Gly,1/1,\N,Unknown significance,\N,missense_variant,22.8,0.0000864753,EXAC_AMR_AF,TSPEAR
505727,21:45971270:C>G,NM_198693.2:c.72G>C,NP_941966.1:p.Glu24Asp,1/1,\N,Unknown significance,\N,missense_variant,22.8,0.000347464,EXAC_EAS_AF,TSPEAR
505728,21:45971275:G>A,NM_198693.2:c.67C>T,NP_941966.1:p.Pro23Ser,1/1,\N,Unknown significance,\N,missense_variant,23.9,0.0014,1KG_AMR_AF,TSPEAR
505729,21:45971276:G>A,NM_198693.2:c.66C>T,NP_941966.1:p.Cys22=,1/1,\N,Unknown significance,\N,synonymous_variant,4.113,0.0000971817,EXAC_AFR_AF,TSPEAR
505730,21:45971280:T>G,NM_198693.2:c.62A>C,NP_941966.1:p.Asp21Ala,1/1,\N,Unknown significance,\N,missense_variant,23.4,0.0000608717,EXAC_SAS_AF,TSPEAR
505731,21:45971281:C>T,NM_198693.2:c.61G>A,NP_941966.1:p.Asp21Asn,1/1,\N,Likely benign,\N,missense_variant,22.9,0.0000609162,EXAC_SAS_AF,TSPEAR
505732,21:45971282:G>A,NM_198693.2:c.60C>T,NP_941966.1:p.Asp20=,1/1,\N,Unknown significance,\N,synonymous_variant,6.648,0.00011566,EXAC_EAS_AF,TSPEAR
505733,21:45971283:T>A,NM_198693.2:c.59A>T,NP_941966.1:p.Asp20Val,1/1,\N,Unknown significance,\N,missense_variant,20.5,\N,\N,TSPEAR
505734,21:45971283:T>C,NM_198693.2:c.59A>G,NP_941966.1:p.Asp20Gly,1/1,\N,Unknown significance,\N,missense_variant,23,0.000030021,EXAC_NFE_AF,TSPEAR
505735,21:45971285:C>T,NM_198693.2:c.57G>A,NP_941966.1:p.Val19=,1/1,\N,Unknown significance,\N,synonymous_variant,9.479,0.0014,1KG_AMR_AF,TSPEAR
505736,21:45971294:G>A,NM_198693.2:c.48C>T,NP_941966.1:p.Ser16=,1/1,\N,Unknown significance,\N,synonymous_variant,2.243,0.0008,1KG_AFR_AF,TSPEAR
505737,21:45971295:G>C,NM_198693.2:c.47C>G,NP_941966.1:p.Ser16Cys,1/1,\N,Unknown significance,\N,missense_variant,22.2,\N,\N,TSPEAR
505738,21:45971297:G>A,NM_198693.2:c.45C>T,NP_941966.1:p.Asn15=,1/1,\N,Unknown significance,\N,synonymous_variant,0.237,\N,\N,TSPEAR
505739,21:45971298:T>TCC,NM_198693.2:c.43_44insGG,NP_941966.1:p.Asn15ArgfsTer30,1/1,\N,Unknown significance,\N,frameshift_variant,17.57,\N,\N,TSPEAR
505740,21:45971299:T>C,NM_198693.2:c.43A>G,NP_941966.1:p.Asn15Asp,1/1,\N,Benign,\N,missense_variant,0.001,0.372204,EXAC_EAS_AF,TSPEAR
505741,21:45971300:G>A,NM_198693.2:c.42C>T,NP_941966.1:p.Thr14=,1/1,\N,Unknown significance,\N,synonymous_variant,1.095,0.0008,1KG_AFR_AF,TSPEAR
505742,21:45971300:G>T,NM_198693.2:c.42C>A,NP_941966.1:p.Thr14=,1/1,\N,Unknown significance,\N,synonymous_variant,0.111,\N,\N,TSPEAR
505743,21:45971305:AGGCGCTGGAGCAGAT>A,NM_198693.2:c.22_36del,NP_941966.1:p.Ile8_Ala12del,1/1,\N,Unknown significance,\N,inframe_deletion,14.6,\N,\N,TSPEAR
505744,21:45971307:G>A,NM_198693.2:c.35C>T,NP_941966.1:p.Ala12Val,1/1,\N,Likely benign,\N,missense_variant,16.17,0.000605222,EXAC_AMR_AF,TSPEAR
505745,21:45971308:C>T,NM_198693.2:c.34G>A,NP_941966.1:p.Ala12Thr,1/1,\N,Likely benign,\N,missense_variant,0.011,0.000116279,EVS_EA_AF,TSPEAR
505746,21:45971309:G>A,NM_198693.2:c.33C>T,NP_941966.1:p.Ser11=,1/1,\N,Benign,\N,synonymous_variant,9.602,0.0212,1KG_AFR_AF,TSPEAR
505747,21:45971309:G>C,NM_198693.2:c.33C>G,NP_941966.1:p.Ser11Arg,1/1,\N,Unknown significance,\N,missense_variant,23.3,0.00453583,EXAC_FIN_AF,TSPEAR
505748,21:45971310:C>CA,NM_198693.2:c.31_32insT,NP_941966.1:p.Ser11MetfsTer18,1/1,\N,Unknown significance,\N,frameshift_variant,20.7,0.000096302,EXAC_AFR_AF,TSPEAR
505749,21:45971313:G>A,NM_198693.2:c.29C>T,NP_941966.1:p.Ser10Phe,1/1,\N,Unknown significance,\N,missense_variant,24.3,\N,\N,TSPEAR
505750,21:45971320:T>A,NM_198693.2:c.22A>T,NP_941966.1:p.Ile8Phe,1/1,\N,Likely benign,\N,missense_variant,12.65,0.0000670601,EXAC_SAS_AF,TSPEAR
505751,21:45971320:T>C,NM_198693.2:c.22A>G,NP_941966.1:p.Ile8Val,1/1,\N,Likely benign,\N,missense_variant,0.001,0.001,1KG_EAS_AF,TSPEAR
505752,21:45971322:G>T,NM_198693.2:c.20C>A,NP_941966.1:p.Ser7Tyr,1/1,\N,Unknown significance,\N,missense_variant,23.5,0.0000964134,EXAC_AFR_AF,TSPEAR
505753,21:45971324:C>T,NM_198693.2:c.18G>A,NP_941966.1:p.Met6Ile,1/1,\N,Unknown significance,\N,missense_variant,11.19,0.000116279,EVS_EA_AF,TSPEAR
505754,21:45971326:T>A,NM_198693.2:c.16A>T,NP_941966.1:p.Met6Leu,1/1,\N,Likely benign,\N,missense_variant,8.913,0.000192864,EXAC_AFR_AF,TSPEAR
505755,21:45971330:G>A,NM_198693.2:c.12C>T,NP_941966.1:p.Ser4=,1/1,\N,Unknown significance,\N,synonymous_variant,3.128,0.001,1KG_EAS_AF|1KG_EUR_AF,TSPEAR
505756,21:45971333:G>T,NM_198693.2:c.9C>A,NP_941966.1:p.Ala3=,1/1,\N,Unknown significance,\N,synonymous_variant,0.016,0.000907853,EVS_AA_AF,TSPEAR
505757,21:45971335:C>A,NM_198693.2:c.7G>T,NP_941966.1:p.Ala3Ser,1/1,\N,Unknown significance,\N,missense_variant,21.5,0.0000965624,EXAC_AFR_AF,TSPEAR
505758,21:45971335:C>T,NM_198693.2:c.7G>A,NP_941966.1:p.Ala3Thr,1/1,\N,Benign,\N,missense_variant,22.5,0.1415,1KG_AFR_AF,TSPEAR
505759,21:45971336:G>A,NM_198693.2:c.6C>T,NP_941966.1:p.Ala2=,1/1,\N,Unknown significance,\N,synonymous_variant,4.707,0.000147863,EXAC_SAS_AF,TSPEAR
505760,21:45971340:A>G,NM_198693.2:c.2T>C,NP_941966.1:p.Met1?,1/1,\N,Likely benign,\N,start_lost,9.209,0.0000152537,EXAC_NFE_AF,TSPEAR
505761,21:45971347:A>G,NM_198693.2:c.-6T>C,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,4.44,0.001,1KG_EAS_AF,TSPEAR
505762,21:45971350:G>A,NM_198693.2:c.-9C>T,\N,1/1,\N,Benign,\N,5_prime_UTR_variant,9.03,0.0058,1KG_AMR_AF,TSPEAR
505763,21:45971352:G>A,NM_198693.2:c.-11C>T,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,9.222,0.001,1KG_SAS_AF,TSPEAR
505764,21:45971356:G>A,NM_198693.2:c.-15C>T,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,11.71,0.0000870171,EXAC_SAS_AF,TSPEAR
505765,21:45971357:A>C,NM_198693.2:c.-16T>G,\N,1/1,\N,Benign,\N,5_prime_UTR_variant,10.59,0.0816279,EVS_EA_AF,TSPEAR
505766,21:45971357:A>T,NM_198693.2:c.-16T>A,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,11.19,\N,\N,TSPEAR
505767,21:45971359:G>A,NM_198693.2:c.-18C>T,\N,1/1,\N,Benign,\N,5_prime_UTR_variant,11.51,0.006,1KG_EAS_AF,TSPEAR
505768,21:45971361:G>A,NM_198693.2:c.-20C>T,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,11.61,0.0014,1KG_AMR_AF,TSPEAR
505769,21:45971369:G>A,NM_198693.2:c.-28C>T,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,11.2,0.0000869414,EXAC_AMR_AF,TSPEAR
505770,21:45971371:AGGTGTGT>A,NM_198693.2:c.-37_-31del,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,12.3,\N,\N,TSPEAR
505771,21:45971372:G>GGTGTGTGAGTGAGTGA,NM_198693.2:c.-47_-32dup,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,8.497,\N,\N,TSPEAR
505772,21:45971376:T>A,NM_198693.2:c.-35A>T,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,8.696,\N,\N,TSPEAR
505773,21:45971376:T>TGA,NM_198693.2:c.-36_-35insTC,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,\N,\N,\N,TSPEAR
505774,21:45971376:T>TGTGAGTGA,NM_198693.2:c.-43_-36dup,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,6.926,\N,\N,TSPEAR
505775,21:45971376:TGTGA>T,NM_198693.2:c.-39_-36del,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,7.902,\N,\N,TSPEAR
505776,21:45971377:G>A,NM_198693.2:c.-36C>T,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,7.472,0.000107596,EXAC_SAS_AF,TSPEAR
505777,21:45971380:A>AAG,NM_198693.2:c.-40_-39insCT,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,\N,\N,\N,TSPEAR
505778,21:45971380:A>AGCGAGTGAGTGT,NM_198693.2:c.-40_-39insACACTCACTCGC,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,0.125,\N,\N,TSPEAR
505779,21:45971380:A>AGTGAGTGAGTGAGTGAGTGAGTGT,NM_198693.2:c.-40_-39insACACTCACTCACTCACTCACTCAC,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,0.044,0.002,1KG_EUR_AF,TSPEAR
505780,21:45971380:A>AGTGAGTGAGTGAGTGAGTGT,NM_198693.2:c.-40_-39insACACTCACTCACTCACTCAC,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,\N,\N,\N,TSPEAR
505781,21:45971380:A>AGTGAGTGAGTGT,NM_198693.2:c.-40_-39insACACTCACTCAC,\N,1/1,\N,Benign,\N,5_prime_UTR_variant,0.125,0.8343,1KG_AFR_AF,TSPEAR
505782,21:45971380:A>AGTGAGTGT,NM_198693.2:c.-40_-39insACACTCAC,\N,1/1,\N,Benign,\N,5_prime_UTR_variant,0.18,0.0491,1KG_SAS_AF,TSPEAR
505783,21:45971380:A>T,NM_198693.2:c.-39T>A,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,0.525,\N,\N,TSPEAR
505784,21:45971380:AGTGAGTGAGTGTGTGTGTGAGTGT>A,NM_144991.2:c.303+16265_303+16288del,\N,\N,2/11,Unknown significance,\N,intron_variant,5.596,\N,\N,TSPEAR
505785,21:45971381:G>A,NM_198693.2:c.-40C>T,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,1.25,0.001,1KG_SAS_AF,TSPEAR
505786,21:45971382:T>C,NM_198693.2:c.-41A>G,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,6.96,0.0000155948,EXAC_NFE_AF,TSPEAR
505787,21:45971383:G>GAGTGAGTGTGTC,NM_198693.2:c.-43_-42insGACACACTCACT,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,3.756,\N,\N,TSPEAR
505788,21:45971384:A>AGTGAGTGT,NM_198693.2:c.-44_-43insACACTCAC,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,\N,\N,\N,TSPEAR
505789,21:45971384:A>AGTGAGTGTGTGAGTGAGTGTGTGT,NM_198693.2:c.-44_-43insACACACACTCACTCACACACTCAC,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,\N,\N,\N,TSPEAR
505790,21:45971384:AGTGAGTGTGTGT>A,NM_144991.2:c.303+16273_303+16284del,\N,\N,2/11,Unknown significance,\N,intron_variant,6.508,\N,\N,TSPEAR
505791,21:45971386:T>TAGGCCTGCTGGCAGGGG,NM_198693.2:c.-46_-45insCCCCTGCCAGCAGGCCT,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,5.489,\N,\N,TSPEAR
505792,21:45971387:G>GAGTGTGTGAGTT,NM_198693.2:c.-47_-46insAACTCACACACT,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,2.712,\N,\N,TSPEAR
505793,21:45971388:A>AGTGTGTGAGTGAGTGTGT,NM_144991.2:c.303+16280_303+16281insACACACTCACTCACACAC,\N,\N,2/11,Unknown significance,\N,intron_variant,0.227,0.000200682,EXAC_AFR_AF,TSPEAR
505794,21:45971388:A>AGTGTGTGAGTGT,NM_144991.2:c.303+16280_303+16281insACACTCACACAC,\N,\N,2/11,Unknown significance,\N,intron_variant,0.392,0.000200682,EXAC_AFR_AF,TSPEAR
505795,21:45971388:AGTGT>A,NM_144991.2:c.303+16277_303+16280del,\N,\N,2/11,Unknown significance,\N,intron_variant,5.434,0.0000871536,EXAC_AMR_AF,TSPEAR
505796,21:45971390:T>TGTGTGAGTGA,NM_144991.2:c.303+16278_303+16279insTCACTCACAC,\N,\N,2/11,Unknown significance,\N,intron_variant,1.769,\N,\N,TSPEAR
505797,21:45971392:T>A,NM_144991.2:c.303+16277A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.869,0.000907853,EVS_AA_AF,TSPEAR
505798,21:45971392:T>TGTGA,NM_144991.2:c.303+16276_303+16277insTCAC,\N,\N,2/11,Unknown significance,\N,intron_variant,0.909,0.0000627097,EXAC_NFE_AF,TSPEAR
505799,21:45971392:T>TGTGAGTGA,NM_144991.2:c.303+16276_303+16277insTCACTCAC,\N,\N,2/11,Benign,\N,intron_variant,0.654,0.0148485,EXAC_FIN_AF,TSPEAR
505800,21:45971393:G>GTGAGTGAGTGTT,NM_144991.2:c.303+16275_303+16276insAACACTCACTCA,\N,\N,2/11,Unknown significance,\N,intron_variant,0.503,\N,\N,TSPEAR
505801,21:45971394:T>G,NM_144991.2:c.303+16275A>C,\N,\N,2/11,Unknown significance,\N,intron_variant,3.649,0.001,1KG_EAS_AF,TSPEAR
505802,21:45971396:T>A,NM_144991.2:c.303+16273A>T,\N,\N,2/11,Benign,\N,intron_variant,0.236,0.0143,1KG_SAS_AF,TSPEAR
505803,21:45971400:A>T,NM_144991.2:c.303+16269T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.014,0.002,1KG_EUR_AF,TSPEAR
505804,21:45971404:T>A,NM_144991.2:c.303+16265A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.617,0.001,1KG_EAS_AF|1KG_EUR_AF|1KG_SAS_AF,TSPEAR
505805,21:45971405:G>A,NM_144991.2:c.303+16264C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,4.257,0.0008,1KG_AFR_AF,TSPEAR
505806,21:45971406:T>G,NM_144991.2:c.303+16263A>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.176,0.001,1KG_EAS_AF,TSPEAR
505807,21:45971408:A>T,NM_144991.2:c.303+16261T>A,\N,\N,2/11,Benign,\N,intron_variant,0.391,0.0219,1KG_AFR_AF,TSPEAR
505808,21:45971409:G>A,NM_144991.2:c.303+16260C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.486,\N,\N,TSPEAR
505809,21:45971419:G>T,NM_144991.2:c.303+16250C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.979,0.001,1KG_SAS_AF,TSPEAR
505810,21:45971420:T>A,NM_144991.2:c.303+16249A>T,\N,\N,2/11,Benign,\N,intron_variant,5.542,0.0072,1KG_SAS_AF,TSPEAR
505811,21:45971426:C>T,NM_144991.2:c.303+16243G>A,\N,\N,2/11,Benign,\N,intron_variant,5.654,0.369,1KG_EAS_AF,TSPEAR
505812,21:45971431:T>C,NM_144991.2:c.303+16238A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,3.165,0.003,1KG_AFR_AF,TSPEAR
505813,21:45971432:G>A,NM_144991.2:c.303+16237C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.414,0.003,1KG_AFR_AF,TSPEAR
505814,21:45971438:T>C,NM_144991.2:c.303+16231A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,7.926,0.001,1KG_SAS_AF,TSPEAR
505815,21:45971443:C>G,NM_144991.2:c.303+16226G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,10.52,0.001,1KG_SAS_AF,TSPEAR
505816,21:45971461:C>T,NM_144991.2:c.303+16208G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,5.566,\N,\N,TSPEAR
505817,21:45971463:G>A,NM_144991.2:c.303+16206C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,6.914,\N,\N,TSPEAR
505818,21:45971477:G>C,NM_144991.2:c.303+16192C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.356,0.002,1KG_EAS_AF,TSPEAR
505819,21:45971497:C>T,NM_144991.2:c.303+16172G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.893,\N,\N,TSPEAR
505820,21:45971505:T>A,NM_144991.2:c.303+16164A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,9.704,0.001,1KG_EAS_AF,TSPEAR
505821,21:45971521:C>G,NM_144991.2:c.303+16148G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.74,0.0008,1KG_AFR_AF,TSPEAR
505822,21:45971522:G>T,NM_144991.2:c.303+16147C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.819,0.001,1KG_EUR_AF,TSPEAR
505823,21:45971525:A>G,NM_144991.2:c.303+16144T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,6.729,0.0015,1KG_AFR_AF,TSPEAR
505824,21:45971563:T>C,NM_144991.2:c.303+16106A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,7.927,\N,\N,TSPEAR
505825,21:45971571:C>G,NM_144991.2:c.303+16098G>C,\N,\N,2/11,Benign,\N,intron_variant,10.47,0.143,1KG_AFR_AF,TSPEAR
505826,21:45971573:G>A,NM_144991.2:c.303+16096C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,10.71,0.0008,1KG_AFR_AF,TSPEAR
505827,21:45971585:C>T,NM_144991.2:c.303+16084G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.214,0.001,1KG_EUR_AF,TSPEAR
505828,21:45971606:G>A,NM_144991.2:c.303+16063C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.083,0.001,1KG_EAS_AF,TSPEAR
505829,21:45971609:G>C,NM_144991.2:c.303+16060C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.073,0.001,1KG_SAS_AF,TSPEAR
505830,21:45971635:A>G,NM_144991.2:c.303+16034T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,4.358,0.0038,1KG_AFR_AF,TSPEAR
505831,21:45971637:C>T,NM_144991.2:c.303+16032G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,5.882,0.0008,1KG_AFR_AF,TSPEAR
505832,21:45971643:G>A,NM_144991.2:c.303+16026C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,4.067,0.001,1KG_SAS_AF,TSPEAR
505833,21:45971658:C>G,NM_144991.2:c.303+16011G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.683,0.003,1KG_AFR_AF,TSPEAR
505834,21:45971698:C>T,NM_144991.2:c.303+15971G>A,\N,\N,2/11,Benign,\N,intron_variant,4.614,0.005,1KG_EUR_AF,TSPEAR
505835,21:45971700:T>C,NM_144991.2:c.303+15969A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,2.326,\N,\N,TSPEAR
505836,21:45971710:C>T,NM_144991.2:c.303+15959G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.021,0.001,1KG_SAS_AF,TSPEAR
505837,21:45971728:C>T,NM_144991.2:c.303+15941G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.294,\N,\N,TSPEAR
505838,21:45971729:G>C,NM_144991.2:c.303+15940C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.551,0.0038,1KG_AFR_AF,TSPEAR
505839,21:45971766:G>A,NM_144991.2:c.303+15903C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.599,0.001,1KG_EAS_AF,TSPEAR
505840,21:45971802:T>C,NM_144991.2:c.303+15867A>G,\N,\N,2/11,Benign,\N,intron_variant,0.046,0.7147,1KG_SAS_AF,TSPEAR
505841,21:45971827:C>T,NM_144991.2:c.303+15842G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.16,0.003,1KG_EAS_AF,TSPEAR
505842,21:45971834:G>A,NM_144991.2:c.303+15835C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.685,0.003,1KG_EAS_AF,TSPEAR
505843,21:45971840:C>A,NM_144991.2:c.303+15829G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.151,0.001,1KG_EAS_AF,TSPEAR
505844,21:45971863:C>A,NM_144991.2:c.303+15806G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,5.879,0.002,1KG_EUR_AF,TSPEAR
505845,21:45971893:G>C,NM_144991.2:c.303+15776C>G,\N,\N,2/11,Benign,\N,intron_variant,4.828,0.0746,1KG_SAS_AF,TSPEAR
505846,21:45971905:G>A,NM_144991.2:c.303+15764C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,5.867,0.0008,1KG_AFR_AF,TSPEAR
505847,21:45971906:G>C,NM_144991.2:c.303+15763C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,2.168,0.002,1KG_EUR_AF,TSPEAR
505848,21:45971931:T>C,NM_144991.2:c.303+15738A>G,\N,\N,2/11,Benign,\N,intron_variant,0.046,0.7147,1KG_SAS_AF,TSPEAR
505849,21:45971961:C>A,NM_144991.2:c.303+15708G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.98,\N,\N,TSPEAR
505850,21:45971975:G>T,NM_144991.2:c.303+15694C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.449,0.003,1KG_EUR_AF,TSPEAR
505851,21:45971988:G>T,NM_144991.2:c.303+15681C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.417,0.001,1KG_SAS_AF,TSPEAR
505852,21:45972015:C>A,NM_144991.2:c.303+15654G>T,\N,\N,2/11,Benign,\N,intron_variant,6.977,0.006,1KG_EAS_AF,TSPEAR
505853,21:45972025:C>T,NM_144991.2:c.303+15644G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.861,0.001,1KG_EUR_AF,TSPEAR
505854,21:45972082:G>A,NM_144991.2:c.303+15587C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.791,0.001,1KG_EUR_AF,TSPEAR
505855,21:45972106:T>C,NM_144991.2:c.303+15563A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.54,0.001,1KG_EUR_AF,TSPEAR
505856,21:45972133:GAC>G,NM_144991.2:c.303+15534_303+15535del,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
505857,21:45972160:G>C,NM_144991.2:c.303+15509C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,11.92,0.0023,1KG_AFR_AF,TSPEAR
505858,21:45972194:AC>A,NM_144991.2:c.303+15474del,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
505859,21:45972195:C>T,NM_144991.2:c.303+15474G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,6.002,\N,\N,TSPEAR
505860,21:45972198:C>G,NM_144991.2:c.303+15471G>C,\N,\N,2/11,Benign,\N,intron_variant,0.807,0.7147,1KG_SAS_AF,TSPEAR
505861,21:45972206:G>C,NM_144991.2:c.303+15463C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.808,0.001,1KG_EAS_AF,TSPEAR
505862,21:45972210:C>G,NM_144991.2:c.303+15459G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.207,\N,\N,TSPEAR
505863,21:45972228:C>T,NM_144991.2:c.303+15441G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.904,0.0038,1KG_AFR_AF,TSPEAR
505864,21:45972256:C>T,NM_144991.2:c.303+15413G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.859,0.0008,1KG_AFR_AF,TSPEAR
505865,21:45972260:A>C,NM_144991.2:c.303+15409T>G,\N,\N,2/11,Benign,\N,intron_variant,0.201,0.7178,1KG_SAS_AF,TSPEAR
505866,21:45972308:C>T,NM_144991.2:c.303+15361G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,5.814,0.0045,1KG_AFR_AF,TSPEAR
505867,21:45972332:C>T,NM_144991.2:c.303+15337G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.821,0.002,1KG_EUR_AF,TSPEAR
505868,21:45972333:G>A,NM_144991.2:c.303+15336C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.747,0.001,1KG_EUR_AF,TSPEAR
505869,21:45972338:C>T,NM_144991.2:c.303+15331G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.617,0.001,1KG_EAS_AF,TSPEAR
505870,21:45972341:G>A,NM_144991.2:c.303+15328C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.318,\N,\N,TSPEAR
505871,21:45972350:T>G,NM_144991.2:c.303+15319A>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.771,\N,\N,TSPEAR
505872,21:45972354:A>T,NM_144991.2:c.303+15315T>A,\N,\N,2/11,Benign,\N,intron_variant,0.068,0.1879,1KG_EUR_AF,TSPEAR
505873,21:45972414:G>A,NM_144991.2:c.303+15255C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.827,0.001,1KG_EUR_AF,TSPEAR
505874,21:45972436:C>G,NM_144991.2:c.303+15233G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.779,0.0014,1KG_AMR_AF,TSPEAR
505875,21:45972485:C>G,NM_144991.2:c.303+15184G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.738,\N,\N,TSPEAR
505876,21:45972490:C>T,NM_144991.2:c.303+15179G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.088,\N,\N,TSPEAR
505877,21:45972491:G>A,NM_144991.2:c.303+15178C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.982,\N,\N,TSPEAR
505878,21:45972519:G>C,NM_144991.2:c.303+15150C>G,\N,\N,2/11,Benign,\N,intron_variant,0.774,0.1422,1KG_AFR_AF,TSPEAR
505879,21:45972546:C>T,NM_144991.2:c.303+15123G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.07,\N,\N,TSPEAR
505880,21:45972562:A>T,NM_144991.2:c.303+15107T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.818,\N,\N,TSPEAR
505881,21:45972592:C>T,NM_144991.2:c.303+15077G>A,\N,\N,2/11,Benign,\N,intron_variant,3.296,0.0199,1KG_EUR_AF,TSPEAR
505882,21:45972595:C>T,NM_144991.2:c.303+15074G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.85,\N,\N,TSPEAR
505883,21:45972603:C>T,NM_144991.2:c.303+15066G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.403,0.001,1KG_SAS_AF,TSPEAR
505884,21:45972627:A>G,NM_144991.2:c.303+15042T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,3.588,\N,\N,TSPEAR
505885,21:45972632:C>A,NM_144991.2:c.303+15037G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,6.085,\N,\N,TSPEAR
505886,21:45972652:C>T,NM_144991.2:c.303+15017G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.657,\N,\N,TSPEAR
505887,21:45972653:G>A,NM_144991.2:c.303+15016C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.025,0.0014,1KG_AMR_AF,TSPEAR
505888,21:45972681:C>T,NM_144991.2:c.303+14988G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.497,\N,\N,TSPEAR
505889,21:45972686:G>T,NM_144991.2:c.303+14983C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.456,0.001,1KG_EUR_AF,TSPEAR
505890,21:45972696:C>T,NM_144991.2:c.303+14973G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.187,\N,\N,TSPEAR
505891,21:45972697:G>A,NM_144991.2:c.303+14972C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.322,\N,\N,TSPEAR
505892,21:45972700:C>G,NM_144991.2:c.303+14969G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.849,\N,\N,TSPEAR
505893,21:45972711:G>A,NM_144991.2:c.303+14958C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.058,0.002,1KG_EAS_AF,TSPEAR
505894,21:45972739:CCTCCGACCTCTCAGGGGTGATGTCTGTGAAGA>C,NM_144991.2:c.303+14898_303+14929del,\N,\N,2/11,Benign,\N,intron_variant,0.609,0.0218,1KG_EAS_AF,TSPEAR
505895,21:45972756:G>C,NM_144991.2:c.303+14913C>G,\N,\N,2/11,Benign,\N,intron_variant,0.201,0.3681,1KG_EAS_AF,TSPEAR
505896,21:45972782:G>A,NM_144991.2:c.303+14887C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.143,\N,\N,TSPEAR
505897,21:45972794:T>C,NM_144991.2:c.303+14875A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,2.484,0.001,1KG_EUR_AF,TSPEAR
505898,21:45972806:G>A,NM_144991.2:c.303+14863C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.14,\N,\N,TSPEAR
505899,21:45972839:G>A,NM_144991.2:c.303+14830C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.814,\N,\N,TSPEAR
505900,21:45972842:G>A,NM_144991.2:c.303+14827C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.168,\N,\N,TSPEAR
505901,21:45972853:G>A,NM_144991.2:c.303+14816C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.254,0.0008,1KG_AFR_AF,TSPEAR
505902,21:45972860:C>T,NM_144991.2:c.303+14809G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.871,\N,\N,TSPEAR
505903,21:45972864:G>A,NM_144991.2:c.303+14805C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.493,0.001,1KG_SAS_AF,TSPEAR
505904,21:45972864:G>C,NM_144991.2:c.303+14805C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.473,\N,\N,TSPEAR
505905,21:45972943:C>T,NM_144991.2:c.303+14726G>A,\N,\N,2/11,Benign,\N,intron_variant,2.092,0.0092,1KG_SAS_AF,TSPEAR
505906,21:45972944:G>A,NM_144991.2:c.303+14725C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.874,0.0023,1KG_AFR_AF,TSPEAR
505907,21:45972964:C>G,NM_144991.2:c.303+14705G>C,\N,\N,2/11,Benign,\N,intron_variant,0.666,0.006,1KG_EAS_AF,TSPEAR
505908,21:45972966:CT>C,NM_144991.2:c.303+14702del,\N,\N,2/11,Unknown significance,\N,intron_variant,1.594,0.002,1KG_EUR_AF,TSPEAR
505909,21:45972997:C>T,NM_144991.2:c.303+14672G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.906,0.001,1KG_SAS_AF,TSPEAR
505910,21:45973060:C>T,NM_144991.2:c.303+14609G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.364,0.001,1KG_EAS_AF,TSPEAR
505911,21:45973072:C>G,NM_144991.2:c.303+14597G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.345,0.0038,1KG_AFR_AF,TSPEAR
505912,21:45973077:C>T,NM_144991.2:c.303+14592G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.019,\N,\N,TSPEAR
505913,21:45973087:A>G,NM_144991.2:c.303+14582T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,3.377,0.001,1KG_EAS_AF,TSPEAR
505914,21:45973096:C>T,NM_144991.2:c.303+14573G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.262,\N,\N,TSPEAR
505915,21:45973097:G>A,NM_144991.2:c.303+14572C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.562,\N,\N,TSPEAR
505916,21:45973099:G>C,NM_144991.2:c.303+14570C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.574,\N,\N,TSPEAR
505917,21:45973108:A>G,NM_144991.2:c.303+14561T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.868,\N,\N,TSPEAR
505918,21:45973112:G>C,NM_144991.2:c.303+14557C>G,\N,\N,2/11,Benign,\N,intron_variant,0.06,0.1952,1KG_AFR_AF,TSPEAR
505919,21:45973118:T>G,NM_144991.2:c.303+14551A>C,\N,\N,2/11,Benign,\N,intron_variant,2.613,0.031,1KG_AFR_AF,TSPEAR
505920,21:45973132:C>G,NM_144991.2:c.303+14537G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.041,0.001,1KG_EUR_AF,TSPEAR
505921,21:45973157:GA>G,NM_144991.2:c.303+14511del,\N,\N,2/11,Benign,\N,intron_variant,0.243,0.1165,1KG_AFR_AF,TSPEAR
505922,21:45973178:C>T,NM_144991.2:c.303+14491G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.581,0.001,1KG_EAS_AF,TSPEAR
505923,21:45973193:A>T,NM_144991.2:c.303+14476T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.271,\N,\N,TSPEAR
505924,21:45973199:A>G,NM_144991.2:c.303+14470T>C,\N,\N,2/11,Benign,\N,intron_variant,0.43,0.1422,1KG_AFR_AF,TSPEAR
505925,21:45973231:T>A,NM_144991.2:c.303+14438A>T,\N,\N,2/11,Benign,\N,intron_variant,3.961,0.37,1KG_EAS_AF,TSPEAR
505926,21:45973237:A>C,NM_144991.2:c.303+14432T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.326,0.0008,1KG_AFR_AF,TSPEAR
505927,21:45973293:G>A,NM_144991.2:c.303+14376C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.126,0.0031,1KG_SAS_AF,TSPEAR
505928,21:45973325:A>C,NM_144991.2:c.303+14344T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.786,0.0008,1KG_AFR_AF,TSPEAR
505929,21:45973352:A>G,NM_144991.2:c.303+14317T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.413,0.001,1KG_EUR_AF,TSPEAR
505930,21:45973367:A>G,NM_144991.2:c.303+14302T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.173,0.0014,1KG_AMR_AF,TSPEAR
505931,21:45973376:T>C,NM_144991.2:c.303+14293A>G,\N,\N,2/11,Benign,\N,intron_variant,2.162,0.0061,1KG_SAS_AF,TSPEAR
505932,21:45973382:C>T,NM_144991.2:c.303+14287G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.838,0.001,1KG_SAS_AF,TSPEAR
505933,21:45973383:G>A,NM_144991.2:c.303+14286C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.823,0.0008,1KG_AFR_AF,TSPEAR
505934,21:45973385:C>T,NM_144991.2:c.303+14284G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.836,\N,\N,TSPEAR
505935,21:45973402:T>C,NM_144991.2:c.303+14267A>G,\N,\N,2/11,Benign,\N,intron_variant,0.354,0.371,1KG_EAS_AF,TSPEAR
505936,21:45973424:A>G,NM_144991.2:c.303+14245T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.252,\N,\N,TSPEAR
505937,21:45973434:C>A,NM_144991.2:c.303+14235G>T,\N,\N,2/11,Benign,\N,intron_variant,4.33,0.1422,1KG_AFR_AF,TSPEAR
505938,21:45973484:GA>G,NM_144991.2:c.303+14184del,\N,\N,2/11,Unknown significance,\N,intron_variant,0.149,\N,\N,TSPEAR
505939,21:45973492:A>G,NM_144991.2:c.303+14177T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.748,0.0008,1KG_AFR_AF,TSPEAR
505940,21:45973502:A>C,NM_144991.2:c.303+14167T>G,\N,\N,2/11,Benign,\N,intron_variant,1.295,0.0144,1KG_AFR_AF,TSPEAR
505941,21:45973509:A>G,NM_144991.2:c.303+14160T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.026,\N,\N,TSPEAR
505942,21:45973529:G>A,NM_144991.2:c.303+14140C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.519,0.0038,1KG_AFR_AF,TSPEAR
505943,21:45973534:T>G,NM_144991.2:c.303+14135A>C,\N,\N,2/11,Benign,\N,intron_variant,2.948,0.006,1KG_EAS_AF,TSPEAR
505944,21:45973605:A>AC,NM_144991.2:c.303+14063dup,\N,\N,2/11,Benign,\N,intron_variant,0.982,0.371,1KG_EAS_AF,TSPEAR
505945,21:45973616:C>A,NM_144991.2:c.303+14053G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.222,0.0008,1KG_AFR_AF,TSPEAR
505946,21:45973633:A>G,NM_144991.2:c.303+14036T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.3,0.002,1KG_EUR_AF,TSPEAR
505947,21:45973641:G>C,NM_144991.2:c.303+14028C>G,\N,\N,2/11,Benign,\N,intron_variant,0.493,0.0749,1KG_AFR_AF,TSPEAR
505948,21:45973658:C>T,NM_144991.2:c.303+14011G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.136,\N,\N,TSPEAR
505949,21:45973683:G>A,NM_144991.2:c.303+13986C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.851,0.0015,1KG_AFR_AF,TSPEAR
505950,21:45973689:G>A,NM_144991.2:c.303+13980C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.825,\N,\N,TSPEAR
505951,21:45973701:C>A,NM_144991.2:c.303+13968G>T,\N,\N,2/11,Benign,\N,intron_variant,3.293,0.146,1KG_AFR_AF,TSPEAR
505952,21:45973701:CTC>ATG,NM_144991.2:c.303+13966_303+13968delinsCAT,\N,\N,2/11,Unknown significance,\N,intron_variant,3.086,\N,\N,TSPEAR
505953,21:45973703:C>G,NM_144991.2:c.303+13966G>C,\N,\N,2/11,Benign,\N,intron_variant,0.397,0.0492,1KG_AFR_AF,TSPEAR
505954,21:45973721:C>T,NM_144991.2:c.303+13948G>A,\N,\N,2/11,Benign,\N,intron_variant,3.174,0.1059,1KG_AFR_AF,TSPEAR
505955,21:45973749:T>C,NM_144991.2:c.303+13920A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.033,0.0008,1KG_AFR_AF,TSPEAR
505956,21:45973756:G>A,NM_144991.2:c.303+13913C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.637,0.0008,1KG_AFR_AF,TSPEAR
505957,21:45973765:G>A,NM_144991.2:c.303+13904C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.631,0.001,1KG_EAS_AF,TSPEAR
505958,21:45973776:G>A,NM_144991.2:c.303+13893C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.314,\N,\N,TSPEAR
505959,21:45973807:A>C,NM_144991.2:c.303+13862T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.957,0.001,1KG_SAS_AF,TSPEAR
505960,21:45973840:C>T,NM_144991.2:c.303+13829G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.144,0.0015,1KG_AFR_AF,TSPEAR
505961,21:45973841:G>A,NM_144991.2:c.303+13828C>T,\N,\N,2/11,Benign,\N,intron_variant,0.439,0.005,1KG_EAS_AF,TSPEAR
505962,21:45973878:C>T,NM_144991.2:c.303+13791G>A,\N,\N,2/11,Benign,\N,intron_variant,15.91,0.7137,1KG_SAS_AF,TSPEAR
505963,21:45973906:G>A,NM_144991.2:c.303+13763C>T,\N,\N,2/11,Benign,\N,intron_variant,2.581,0.7137,1KG_SAS_AF,TSPEAR
505964,21:45973926:T>C,NM_144991.2:c.303+13743A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.317,0.0015,1KG_AFR_AF,TSPEAR
505965,21:45973933:G>A,NM_144991.2:c.303+13736C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.969,\N,\N,TSPEAR
505966,21:45973939:G>A,NM_144991.2:c.303+13730C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.454,0.0008,1KG_AFR_AF,TSPEAR
505967,21:45973945:G>GT,NM_144991.2:c.303+13723_303+13724insA,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
505968,21:45973952:T>A,NM_144991.2:c.303+13717A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.289,\N,\N,TSPEAR
505969,21:45973955:T>G,NM_144991.2:c.303+13714A>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.293,0.002,1KG_EAS_AF,TSPEAR
505970,21:45973964:C>T,NM_144991.2:c.303+13705G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.701,\N,\N,TSPEAR
505971,21:45974000:G>C,NM_144991.2:c.303+13669C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.352,\N,\N,TSPEAR
505972,21:45974017:G>T,NM_144991.2:c.303+13652C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.545,0.002,1KG_SAS_AF,TSPEAR
505973,21:45974027:G>A,NM_144991.2:c.303+13642C>T,\N,\N,2/11,Benign,\N,intron_variant,2.268,0.0481,1KG_SAS_AF,TSPEAR
505974,21:45974085:A>G,NM_144991.2:c.303+13584T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.602,0.0008,1KG_AFR_AF,TSPEAR
505975,21:45974091:C>T,NM_144991.2:c.303+13578G>A,\N,\N,2/11,Benign,\N,intron_variant,3.387,0.1407,1KG_AFR_AF,TSPEAR
505976,21:45974114:G>C,NM_144991.2:c.303+13555C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.325,0.0038,1KG_AFR_AF,TSPEAR
505977,21:45974141:G>A,NM_144991.2:c.303+13528C>T,\N,\N,2/11,Benign,\N,intron_variant,3.997,0.0469,1KG_AFR_AF,TSPEAR
505978,21:45974148:A>G,NM_144991.2:c.303+13521T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,5.228,\N,\N,TSPEAR
505979,21:45974150:G>C,NM_144991.2:c.303+13519C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.622,0.001,1KG_EAS_AF,TSPEAR
505980,21:45974169:G>C,NM_144991.2:c.303+13500C>G,\N,\N,2/11,Benign,\N,intron_variant,0.077,0.371,1KG_EAS_AF,TSPEAR
505981,21:45974181:G>C,NM_144991.2:c.303+13488C>G,\N,\N,2/11,Benign,\N,intron_variant,0.637,0.7106,1KG_SAS_AF,TSPEAR
505982,21:45974182:G>A,NM_144991.2:c.303+13487C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.591,0.002,1KG_EAS_AF,TSPEAR
505983,21:45974210:T>A,NM_144991.2:c.303+13459A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.459,\N,\N,TSPEAR
505984,21:45974233:G>C,NM_144991.2:c.303+13436C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.566,0.0014,1KG_AMR_AF,TSPEAR
505985,21:45974234:C>T,NM_144991.2:c.303+13435G>A,\N,\N,2/11,Benign,\N,intron_variant,1.119,0.1233,1KG_AFR_AF,TSPEAR
505986,21:45974241:C>T,NM_144991.2:c.303+13428G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.903,\N,\N,TSPEAR
505987,21:45974262:G>A,NM_144991.2:c.303+13407C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.99,\N,\N,TSPEAR
505988,21:45974278:G>A,NM_144991.2:c.303+13391C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.277,0.0015,1KG_AFR_AF,TSPEAR
505989,21:45974297:GAGA>G,NM_144991.2:c.303+13369_303+13371del,\N,\N,2/11,Benign,\N,intron_variant,4.19,0.0136,1KG_AFR_AF,TSPEAR
505990,21:45974299:GA>G,NM_144991.2:c.303+13369del,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
505991,21:45974326:C>T,NM_144991.2:c.303+13343G>A,\N,\N,2/11,Benign,\N,intron_variant,0.911,0.37,1KG_EAS_AF,TSPEAR
505992,21:45974329:A>G,NM_144991.2:c.303+13340T>C,\N,\N,2/11,Benign,\N,intron_variant,0.718,0.369,1KG_EAS_AF,TSPEAR
505993,21:45974347:G>A,NM_144991.2:c.303+13322C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.562,\N,\N,TSPEAR
505994,21:45974411:T>A,NM_144991.2:c.303+13258A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,6.71,\N,\N,TSPEAR
505995,21:45974465:C>T,NM_144991.2:c.303+13204G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.101,0.0041,1KG_SAS_AF,TSPEAR
505996,21:45974509:C>T,NM_144991.2:c.303+13160G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.881,0.001,1KG_EAS_AF,TSPEAR
505997,21:45974510:T>G,NM_144991.2:c.303+13159A>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.887,0.0029,1KG_AMR_AF,TSPEAR
505998,21:45974521:C>T,NM_144991.2:c.303+13148G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.731,\N,\N,TSPEAR
505999,21:45974526:G>GT,NM_144991.2:c.303+13142dup,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
506000,21:45974526:G>T,NM_144991.2:c.303+13143C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.041,\N,\N,TSPEAR
506001,21:45974527:T>TTG,NM_144991.2:c.303+13141_303+13142insCA,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
506002,21:45974528:G>T,NM_144991.2:c.303+13141C>A,\N,\N,2/11,Benign,\N,intron_variant,1.741,0.3651,1KG_EAS_AF,TSPEAR
506003,21:45974528:GA>TG,NM_144991.2:c.303+13140_303+13141delinsCA,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
506004,21:45974529:A>G,NM_144991.2:c.303+13140T>C,\N,\N,2/11,Benign,\N,intron_variant,3.498,0.3661,1KG_EAS_AF,TSPEAR
506005,21:45974535:C>T,NM_144991.2:c.303+13134G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.138,\N,\N,TSPEAR
506006,21:45974536:G>A,NM_144991.2:c.303+13133C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.676,\N,\N,TSPEAR
506007,21:45974546:C>T,NM_144991.2:c.303+13123G>A,\N,\N,2/11,Benign,\N,intron_variant,0.125,0.0318,1KG_AFR_AF,TSPEAR
506008,21:45974547:G>C,NM_144991.2:c.303+13122C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.097,\N,\N,TSPEAR
506009,21:45974569:G>A,NM_144991.2:c.303+13100C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.923,0.0008,1KG_AFR_AF,TSPEAR
506010,21:45974582:G>A,NM_144991.2:c.303+13087C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.886,0.0008,1KG_AFR_AF,TSPEAR
506011,21:45974591:A>G,NM_144991.2:c.303+13078T>C,\N,\N,2/11,Benign,\N,intron_variant,1.349,0.0333,1KG_AFR_AF,TSPEAR
506012,21:45974612:C>T,NM_144991.2:c.303+13057G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.466,0.0045,1KG_AFR_AF,TSPEAR
506013,21:45974614:G>A,NM_144991.2:c.303+13055C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.804,\N,\N,TSPEAR
506014,21:45974615:G>C,NM_144991.2:c.303+13054C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.25,0.0008,1KG_AFR_AF,TSPEAR
506015,21:45974645:C>T,NM_144991.2:c.303+13024G>A,\N,\N,2/11,Benign,\N,intron_variant,2.188,0.0265,1KG_AFR_AF,TSPEAR
506016,21:45974651:T>TTC,NM_144991.2:c.303+13016_303+13017dup,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
506017,21:45974671:T>C,NM_144991.2:c.303+12998A>G,\N,\N,2/11,Benign,\N,intron_variant,1.281,0.371,1KG_EAS_AF,TSPEAR
506018,21:45974703:C>T,NM_144991.2:c.303+12966G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.625,0.001,1KG_EAS_AF,TSPEAR
506019,21:45974762:G>C,NM_144991.2:c.303+12907C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.067,\N,\N,TSPEAR
506020,21:45974780:A>C,NM_144991.2:c.303+12889T>G,\N,\N,2/11,Benign,\N,intron_variant,0.158,0.369,1KG_EAS_AF,TSPEAR
506021,21:45974781:C>G,NM_144991.2:c.303+12888G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.083,\N,\N,TSPEAR
506022,21:45974782:C>T,NM_144991.2:c.303+12887G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.227,0.001,1KG_SAS_AF,TSPEAR
506023,21:45974785:G>A,NM_144991.2:c.303+12884C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.123,\N,\N,TSPEAR
506024,21:45974811:A>G,NM_144991.2:c.303+12858T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.37,\N,\N,TSPEAR
506025,21:45974835:C>T,NM_144991.2:c.303+12834G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.863,0.002,1KG_SAS_AF,TSPEAR
506026,21:45974842:C>T,NM_144991.2:c.303+12827G>A,\N,\N,2/11,Benign,\N,intron_variant,0.807,0.0092,1KG_SAS_AF,TSPEAR
506027,21:45974843:G>A,NM_144991.2:c.303+12826C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.382,0.0014,1KG_AMR_AF,TSPEAR
506028,21:45974867:T>C,NM_144991.2:c.303+12802A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.96,\N,\N,TSPEAR
506029,21:45974867:T>TA,NM_144991.2:c.303+12801dup,\N,\N,2/11,Benign,\N,intron_variant,0.553,0.0484,1KG_AFR_AF,TSPEAR
506030,21:45974868:A>T,NM_144991.2:c.303+12801T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.182,\N,\N,TSPEAR
506031,21:45974877:G>A,NM_144991.2:c.303+12792C>T,\N,\N,2/11,Benign,\N,intron_variant,3.364,0.369,1KG_EAS_AF,TSPEAR
506032,21:45974903:T>A,NM_144991.2:c.303+12766A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.176,0.001,1KG_SAS_AF,TSPEAR
506033,21:45974925:A>G,NM_144991.2:c.303+12744T>C,\N,\N,2/11,Benign,\N,intron_variant,1.367,0.0401,1KG_AFR_AF,TSPEAR
506034,21:45974974:C>A,NM_144991.2:c.303+12695G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.786,0.001,1KG_SAS_AF,TSPEAR
506035,21:45974975:G>A,NM_144991.2:c.303+12694C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.058,0.002,1KG_EUR_AF,TSPEAR
506036,21:45974984:A>G,NM_144991.2:c.303+12685T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.908,\N,\N,TSPEAR
506037,21:45974989:A>G,NM_144991.2:c.303+12680T>C,\N,\N,2/11,Benign,\N,intron_variant,1.872,0.0144,1KG_AFR_AF,TSPEAR
506038,21:45975011:C>T,NM_144991.2:c.303+12658G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.1,\N,\N,TSPEAR
506039,21:45975015:C>T,NM_144991.2:c.303+12654G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.115,0.001,1KG_SAS_AF,TSPEAR
506040,21:45975016:G>T,NM_144991.2:c.303+12653C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.012,\N,\N,TSPEAR
506041,21:45975026:A>C,NM_144991.2:c.303+12643T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.172,0.002,1KG_EAS_AF,TSPEAR
506042,21:45975041:A>G,NM_144991.2:c.303+12628T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.003,0.001,1KG_EUR_AF,TSPEAR
506043,21:45975044:A>G,NM_144991.2:c.303+12625T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.886,\N,\N,TSPEAR
506044,21:45975048:C>T,NM_144991.2:c.303+12621G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.852,\N,\N,TSPEAR
506045,21:45975049:G>A,NM_144991.2:c.303+12620C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.81,\N,\N,TSPEAR
506046,21:45975056:G>A,NM_144991.2:c.303+12613C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.101,0.0015,1KG_AFR_AF,TSPEAR
506047,21:45975060:C>A,NM_144991.2:c.303+12609G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.656,\N,\N,TSPEAR
506048,21:45975060:C>G,NM_144991.2:c.303+12609G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.803,\N,\N,TSPEAR
506049,21:45975060:C>T,NM_144991.2:c.303+12609G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.542,\N,\N,TSPEAR
506050,21:45975104:C>T,NM_144991.2:c.303+12565G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.32,0.0015,1KG_AFR_AF,TSPEAR
506051,21:45975113:T>C,NM_144991.2:c.303+12556A>G,\N,\N,2/11,Benign,\N,intron_variant,1.834,0.0303,1KG_AFR_AF,TSPEAR
506052,21:45975131:C>T,NM_144991.2:c.303+12538G>A,\N,\N,2/11,Benign,\N,intron_variant,0.107,0.0068,1KG_AFR_AF,TSPEAR
506053,21:45975132:G>A,NM_144991.2:c.303+12537C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.861,\N,\N,TSPEAR
506054,21:45975139:A>G,NM_144991.2:c.303+12530T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.16,0.0008,1KG_AFR_AF,TSPEAR
506055,21:45975187:G>A,NM_144991.2:c.303+12482C>T,\N,\N,2/11,Benign,\N,intron_variant,1.213,0.3671,1KG_EAS_AF,TSPEAR
506056,21:45975203:G>A,NM_144991.2:c.303+12466C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.551,\N,\N,TSPEAR
506057,21:45975215:C>T,NM_144991.2:c.303+12454G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.324,\N,\N,TSPEAR
506058,21:45975218:C>A,NM_144991.2:c.303+12451G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.012,0.0023,1KG_AFR_AF,TSPEAR
506059,21:45975218:C>T,NM_144991.2:c.303+12451G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.011,\N,\N,TSPEAR
506060,21:45975219:G>A,NM_144991.2:c.303+12450C>T,\N,\N,2/11,Benign,\N,intron_variant,3.994,0.0098,1KG_AFR_AF,TSPEAR
506061,21:45975223:GC>G,NM_144991.2:c.303+12445del,\N,\N,2/11,Unknown significance,\N,intron_variant,0.105,0.0045,1KG_AFR_AF,TSPEAR
506062,21:45975225:C>G,NM_144991.2:c.303+12444G>C,\N,\N,2/11,Benign,\N,intron_variant,0.724,0.0098,1KG_AFR_AF,TSPEAR
506063,21:45975225:C>T,NM_144991.2:c.303+12444G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.578,\N,\N,TSPEAR
506064,21:45975236:C>T,NM_144991.2:c.303+12433G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.602,0.001,1KG_EUR_AF,TSPEAR
506065,21:45975257:C>T,NM_144991.2:c.303+12412G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.923,\N,\N,TSPEAR
506066,21:45975270:CG>C,NM_144991.2:c.303+12398del,\N,\N,2/11,Benign,\N,intron_variant,3.568,0.1452,1KG_AFR_AF,TSPEAR
506067,21:45975271:G>A,NM_144991.2:c.303+12398C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.441,0.0015,1KG_AFR_AF,TSPEAR
506068,21:45975298:C>A,NM_144991.2:c.303+12371G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.017,0.001,1KG_SAS_AF,TSPEAR
506069,21:45975298:C>T,NM_144991.2:c.303+12371G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.895,\N,\N,TSPEAR
506070,21:45975299:G>A,NM_144991.2:c.303+12370C>T,\N,\N,2/11,Benign,\N,intron_variant,0.291,0.0182,1KG_AFR_AF,TSPEAR
506071,21:45975313:C>A,NM_144991.2:c.303+12356G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.898,0.004,1KG_EAS_AF,TSPEAR
506072,21:45975357:G>A,NM_144991.2:c.303+12312C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.043,0.001,1KG_EAS_AF,TSPEAR
506073,21:45975378:G>A,NM_144991.2:c.303+12291C>T,\N,\N,2/11,Benign,\N,intron_variant,2.977,0.0416,1KG_AFR_AF,TSPEAR
506074,21:45975390:TAC>T,NM_144991.2:c.303+12277_303+12278del,\N,\N,2/11,Benign,\N,intron_variant,6.648,0.0348,1KG_AFR_AF,TSPEAR
506075,21:45975406:G>A,NM_144991.2:c.303+12263C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.434,\N,\N,TSPEAR
506076,21:45975462:C>T,NM_144991.2:c.303+12207G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.185,0.001,1KG_EAS_AF|1KG_SAS_AF,TSPEAR
506077,21:45975519:A>G,NM_144991.2:c.303+12150T>C,\N,\N,2/11,Benign,\N,intron_variant,1.993,0.3681,1KG_EAS_AF,TSPEAR
506078,21:45975524:G>A,NM_144991.2:c.303+12145C>T,\N,\N,2/11,Benign,\N,intron_variant,2.014,0.7301,1KG_SAS_AF,TSPEAR
506079,21:45975538:C>CT,NM_144991.2:c.303+12130_303+12131insA,\N,\N,2/11,Benign,\N,intron_variant,1.851,0.1475,1KG_AFR_AF,TSPEAR
506080,21:45975539:C>T,NM_144991.2:c.303+12130G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.643,0.002,1KG_SAS_AF,TSPEAR
506081,21:45975539:CGG>C,NM_144991.2:c.303+12128_303+12129del,\N,\N,2/11,Benign,\N,intron_variant,0.147,0.1475,1KG_AFR_AF,TSPEAR
506082,21:45975539:CGG>TC,NM_144991.2:c.303+12128_303+12130delinsGA,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
506083,21:45975632:C>T,NM_144991.2:c.303+12037G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.5,0.0029,1KG_AMR_AF,TSPEAR
506084,21:45975646:C>T,NM_144991.2:c.303+12023G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.602,0.001,1KG_EUR_AF,TSPEAR
506085,21:45975667:C>G,NM_144991.2:c.303+12002G>C,\N,\N,2/11,Benign,\N,intron_variant,2.77,0.0915,1KG_EUR_AF,TSPEAR
506086,21:45975680:C>T,NM_144991.2:c.303+11989G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.24,0.0031,1KG_SAS_AF,TSPEAR
506087,21:45975681:A>G,NM_144991.2:c.303+11988T>C,\N,\N,2/11,Benign,\N,intron_variant,0.807,0.9018,1KG_SAS_AF,TSPEAR
506088,21:45975718:C>T,NM_144991.2:c.303+11951G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,8.014,0.001,1KG_SAS_AF,TSPEAR
506089,21:45975755:C>G,NM_144991.2:c.303+11914G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.445,\N,\N,TSPEAR
506090,21:45975755:C>T,NM_144991.2:c.303+11914G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.17,\N,\N,TSPEAR
506091,21:45975759:C>T,NM_144991.2:c.303+11910G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.536,0.001,1KG_EUR_AF,TSPEAR
506092,21:45975763:C>T,NM_144991.2:c.303+11906G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.739,0.0008,1KG_AFR_AF,TSPEAR
506093,21:45975797:A>C,NM_144991.2:c.303+11872T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.184,\N,\N,TSPEAR
506094,21:45975817:C>T,NM_144991.2:c.303+11852G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.898,\N,\N,TSPEAR
506095,21:45975830:G>A,NM_144991.2:c.303+11839C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.022,0.0023,1KG_AFR_AF,TSPEAR
506096,21:45975835:T>C,NM_144991.2:c.303+11834A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.478,0.0023,1KG_AFR_AF,TSPEAR
506097,21:45975844:G>A,NM_144991.2:c.303+11825C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.955,0.0015,1KG_AFR_AF,TSPEAR
506098,21:45975845:T>TA,NM_144991.2:c.303+11823dup,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
506099,21:45975848:A>G,NM_144991.2:c.303+11821T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.473,0.001,1KG_EAS_AF,TSPEAR
506100,21:45975873:T>TA,NM_144991.2:c.303+11795dup,\N,\N,2/11,Benign,\N,intron_variant,0.19,0.006,1KG_EAS_AF,TSPEAR
506101,21:45975878:C>T,NM_144991.2:c.303+11791G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.156,0.0014,1KG_AMR_AF,TSPEAR
506102,21:45975947:AT>A,NM_144991.2:c.303+11721del,\N,\N,2/11,Unknown significance,\N,intron_variant,0.401,\N,\N,TSPEAR
506103,21:45975977:C>T,NM_144991.2:c.303+11692G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.093,0.0008,1KG_AFR_AF,TSPEAR
506104,21:45975978:G>A,NM_144991.2:c.303+11691C>T,\N,\N,2/11,Benign,\N,intron_variant,0.424,0.0635,1KG_AFR_AF,TSPEAR
506105,21:45975982:C>T,NM_144991.2:c.303+11687G>A,\N,\N,2/11,Benign,\N,intron_variant,1.042,0.005,1KG_EUR_AF,TSPEAR
506106,21:45975983:G>A,NM_144991.2:c.303+11686C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.707,0.002,1KG_SAS_AF,TSPEAR
506107,21:45975986:C>T,NM_144991.2:c.303+11683G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.371,\N,\N,TSPEAR
506108,21:45975988:C>T,NM_144991.2:c.303+11681G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.293,\N,\N,TSPEAR
506109,21:45975989:G>A,NM_144991.2:c.303+11680C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.377,\N,\N,TSPEAR
506110,21:45975998:C>A,NM_144991.2:c.303+11671G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.408,\N,\N,TSPEAR
506111,21:45975998:C>T,NM_144991.2:c.303+11671G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.375,\N,\N,TSPEAR
506112,21:45976011:A>G,NM_144991.2:c.303+11658T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.28,\N,\N,TSPEAR
506113,21:45976013:C>T,NM_144991.2:c.303+11656G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.864,0.003,1KG_AFR_AF,TSPEAR
506114,21:45976014:G>A,NM_144991.2:c.303+11655C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.145,0.0008,1KG_AFR_AF,TSPEAR
506115,21:45976030:G>A,NM_144991.2:c.303+11639C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.978,0.001,1KG_SAS_AF,TSPEAR
506116,21:45976040:C>T,NM_144991.2:c.303+11629G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.026,\N,\N,TSPEAR
506117,21:45976084:C>T,NM_144991.2:c.303+11585G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.188,\N,\N,TSPEAR
506118,21:45976128:G>A,NM_144991.2:c.303+11541C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.247,0.0023,1KG_AFR_AF,TSPEAR
506119,21:45976139:G>A,NM_144991.2:c.303+11530C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.16,\N,\N,TSPEAR
506120,21:45976183:C>T,NM_144991.2:c.303+11486G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.647,\N,\N,TSPEAR
506121,21:45976185:G>C,NM_144991.2:c.303+11484C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.031,0.0008,1KG_AFR_AF,TSPEAR
506122,21:45976201:C>T,NM_144991.2:c.303+11468G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.971,\N,\N,TSPEAR
506123,21:45976202:T>C,NM_144991.2:c.303+11467A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.931,0.002,1KG_EAS_AF,TSPEAR
506124,21:45976207:G>A,NM_144991.2:c.303+11462C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.1,\N,\N,TSPEAR
506125,21:45976212:T>C,NM_144991.2:c.303+11457A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.784,\N,\N,TSPEAR
506126,21:45976220:C>T,NM_144991.2:c.303+11449G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.963,0.001,1KG_SAS_AF,TSPEAR
506127,21:45976228:T>C,NM_144991.2:c.303+11441A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.067,\N,\N,TSPEAR
506128,21:45976234:G>A,NM_144991.2:c.303+11435C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.638,0.002,1KG_SAS_AF,TSPEAR
506129,21:45976239:CAG>C,NM_144991.2:c.303+11428_303+11429del,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
506130,21:45976241:G>A,NM_144991.2:c.303+11428C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.497,\N,\N,TSPEAR
506131,21:45976241:G>C,NM_144991.2:c.303+11428C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.263,\N,\N,TSPEAR
506132,21:45976257:C>CA,NM_144991.2:c.303+11411dup,\N,\N,2/11,Unknown significance,\N,intron_variant,4.002,\N,\N,TSPEAR
506133,21:45976267:T>C,NM_144991.2:c.303+11402A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.883,\N,\N,TSPEAR
506134,21:45976270:C>G,NM_144991.2:c.303+11399G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.625,\N,\N,TSPEAR
506135,21:45976278:A>AC,NM_144991.2:c.303+11390_303+11391insG,\N,\N,2/11,Unknown significance,\N,intron_variant,0.225,\N,\N,TSPEAR
506136,21:45976279:A>C,NM_144991.2:c.303+11390T>G,\N,\N,2/11,Benign,\N,intron_variant,0.048,0.9165,1KG_EUR_AF,TSPEAR
506137,21:45976282:A>C,NM_144991.2:c.303+11387T>G,\N,\N,2/11,Benign,\N,intron_variant,0.019,0.0333,1KG_AFR_AF,TSPEAR
506138,21:45976325:C>T,NM_144991.2:c.303+11344G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.623,0.003,1KG_AFR_AF,TSPEAR
506139,21:45976339:G>C,NM_144991.2:c.303+11330C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.068,\N,\N,TSPEAR
506140,21:45976341:C>T,NM_144991.2:c.303+11328G>A,\N,\N,2/11,Benign,\N,intron_variant,0.148,0.0635,1KG_AFR_AF,TSPEAR
506141,21:45976347:G>A,NM_144991.2:c.303+11322C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.505,\N,\N,TSPEAR
506142,21:45976374:G>A,NM_144991.2:c.303+11295C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.107,\N,\N,TSPEAR
506143,21:45976402:C>T,NM_144991.2:c.303+11267G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.211,0.001,1KG_EUR_AF,TSPEAR
506144,21:45976432:T>C,NM_144991.2:c.303+11237A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.097,0.003,1KG_EAS_AF,TSPEAR
506145,21:45976448:C>T,NM_144991.2:c.303+11221G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.668,0.004,1KG_EUR_AF,TSPEAR
506146,21:45976449:G>A,NM_144991.2:c.303+11220C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.139,0.001,1KG_EAS_AF,TSPEAR
506147,21:45976452:T>G,NM_144991.2:c.303+11217A>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.637,0.001,1KG_EUR_AF,TSPEAR
506148,21:45976468:CAGG>C,NM_144991.2:c.303+11198_303+11200del,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
506149,21:45976485:G>A,NM_144991.2:c.303+11184C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,5.764,0.004,1KG_EAS_AF,TSPEAR
506150,21:45976502:G>A,NM_144991.2:c.303+11167C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.546,\N,\N,TSPEAR
506151,21:45976523:C>T,NM_144991.2:c.303+11146G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.817,\N,\N,TSPEAR
506152,21:45976524:G>A,NM_144991.2:c.303+11145C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.7,\N,\N,TSPEAR
506153,21:45976536:C>T,NM_144991.2:c.303+11133G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.081,0.001,1KG_EAS_AF,TSPEAR
506154,21:45976562:C>T,NM_144991.2:c.303+11107G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.211,\N,\N,TSPEAR
506155,21:45976569:C>T,NM_144991.2:c.303+11100G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.695,\N,\N,TSPEAR
506156,21:45976574:A>G,NM_144991.2:c.303+11095T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.627,\N,\N,TSPEAR
506157,21:45976583:T>C,NM_144991.2:c.303+11086A>G,\N,\N,2/11,Benign,\N,intron_variant,1.531,0.0079,1KG_EAS_AF,TSPEAR
506158,21:45976594:C>G,NM_144991.2:c.303+11075G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,6.372,\N,\N,TSPEAR
506159,21:45976595:C>T,NM_144991.2:c.303+11074G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,7.791,\N,\N,TSPEAR
506160,21:45976608:T>C,NM_144991.2:c.303+11061A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,11.81,0.0008,1KG_AFR_AF,TSPEAR
506161,21:45976609:C>T,NM_144991.2:c.303+11060G>A,\N,\N,2/11,Benign,\N,intron_variant,12.84,0.0144,1KG_AFR_AF,TSPEAR
506162,21:45976678:T>C,NM_144991.2:c.303+10991A>G,\N,\N,2/11,Benign,\N,intron_variant,1.219,0.0099,1KG_EAS_AF,TSPEAR
506163,21:45976682:C>T,NM_144991.2:c.303+10987G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.815,\N,\N,TSPEAR
506164,21:45976697:A>G,NM_144991.2:c.303+10972T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,5.498,0.001,1KG_EAS_AF,TSPEAR
506165,21:45976714:A>C,NM_144991.2:c.303+10955T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,2.13,\N,\N,TSPEAR
506166,21:45976715:A>G,NM_144991.2:c.303+10954T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.849,\N,\N,TSPEAR
506167,21:45976748:A>AG,NM_144991.2:c.303+10920dup,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
506168,21:45976781:C>T,NM_144991.2:c.303+10888G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.475,0.001,1KG_EUR_AF,TSPEAR
506169,21:45976783:C>T,NM_144991.2:c.303+10886G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.303,0.0015,1KG_AFR_AF,TSPEAR
506170,21:45976816:A>G,NM_144991.2:c.303+10853T>C,\N,\N,2/11,Benign,\N,intron_variant,1.25,0.0072,1KG_AMR_AF,TSPEAR
506171,21:45976838:C>T,NM_144991.2:c.303+10831G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.846,\N,\N,TSPEAR
506172,21:45976846:C>T,NM_144991.2:c.303+10823G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.651,0.001,1KG_EAS_AF,TSPEAR
506173,21:45976857:C>A,NM_144991.2:c.303+10812G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.361,\N,\N,TSPEAR
506174,21:45976905:C>T,NM_144991.2:c.303+10764G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.123,0.0029,1KG_AMR_AF,TSPEAR
506175,21:45976937:C>T,NM_144991.2:c.303+10732G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.595,\N,\N,TSPEAR
506176,21:45976938:G>A,NM_144991.2:c.303+10731C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.016,\N,\N,TSPEAR
506177,21:45976940:G>A,NM_144991.2:c.303+10729C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.728,0.0029,1KG_AMR_AF,TSPEAR
506178,21:45976954:G>A,NM_144991.2:c.303+10715C>T,\N,\N,2/11,Benign,\N,intron_variant,2.388,0.0219,1KG_AFR_AF,TSPEAR
506179,21:45976972:A>G,NM_144991.2:c.303+10697T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,3.462,0.0008,1KG_AFR_AF,TSPEAR
506180,21:45976992:G>A,NM_144991.2:c.303+10677C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.753,0.001,1KG_SAS_AF,TSPEAR
506181,21:45976995:C>T,NM_144991.2:c.303+10674G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.319,0.0008,1KG_AFR_AF,TSPEAR
506182,21:45976999:A>G,NM_144991.2:c.303+10670T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.291,\N,\N,TSPEAR
506183,21:45977013:C>T,NM_144991.2:c.303+10656G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.223,0.0015,1KG_AFR_AF,TSPEAR
506184,21:45977014:G>A,NM_144991.2:c.303+10655C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.119,0.001,1KG_EAS_AF,TSPEAR
506185,21:45977063:G>C,NM_144991.2:c.303+10606C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.334,0.0008,1KG_AFR_AF,TSPEAR
506186,21:45977065:C>T,NM_144991.2:c.303+10604G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,7.813,0.001,1KG_EAS_AF,TSPEAR
506187,21:45977109:C>T,NM_144991.2:c.303+10560G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.624,0.0014,1KG_AMR_AF,TSPEAR
506188,21:45977111:T>C,NM_144991.2:c.303+10558A>G,\N,\N,2/11,Benign,\N,intron_variant,1.628,0.1998,1KG_EUR_AF,TSPEAR
506189,21:45977118:G>A,NM_144991.2:c.303+10551C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,4.848,\N,\N,TSPEAR
506190,21:45977175:A>C,NM_144991.2:c.303+10494T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.608,\N,\N,TSPEAR
506191,21:45977210:C>T,NM_144991.2:c.303+10459G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.788,0.0015,1KG_AFR_AF,TSPEAR
506192,21:45977211:G>A,NM_144991.2:c.303+10458C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.571,0.0029,1KG_AMR_AF,TSPEAR
506193,21:45977236:C>G,NM_144991.2:c.303+10433G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,4.772,\N,\N,TSPEAR
506194,21:45977291:A>C,NM_144991.2:c.303+10378T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,3.021,\N,\N,TSPEAR
506195,21:45977348:A>G,NM_144991.2:c.303+10321T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.602,0.001,1KG_EUR_AF,TSPEAR
506196,21:45977372:GA>G,NM_144991.2:c.303+10296del,\N,\N,2/11,Unknown significance,\N,intron_variant,0.215,0.0045,1KG_AFR_AF,TSPEAR
506197,21:45977382:G>T,NM_144991.2:c.303+10287C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,5.589,\N,\N,TSPEAR
506198,21:45977389:C>A,NM_144991.2:c.303+10280G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,7.905,0.001,1KG_EUR_AF,TSPEAR
506199,21:45977396:A>G,NM_144991.2:c.303+10273T>C,\N,\N,2/11,Benign,\N,intron_variant,5.342,0.1316,1KG_AFR_AF,TSPEAR
506200,21:45977408:G>C,NM_144991.2:c.303+10261C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,3.153,0.0008,1KG_AFR_AF,TSPEAR
506201,21:45977415:G>A,NM_144991.2:c.303+10254C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,6.39,0.001,1KG_SAS_AF,TSPEAR
506202,21:45977436:C>T,NM_144991.2:c.303+10233G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,10.95,\N,\N,TSPEAR
506203,21:45977441:C>T,NM_144991.2:c.303+10228G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.973,0.001,1KG_SAS_AF,TSPEAR
506204,21:45977452:G>C,NM_144991.2:c.303+10217C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.09,0.001,1KG_EAS_AF,TSPEAR
506205,21:45977477:G>C,NM_144991.2:c.303+10192C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.086,\N,\N,TSPEAR
506206,21:45977478:G>C,NM_144991.2:c.303+10191C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.383,\N,\N,TSPEAR
506207,21:45977489:C>G,NM_144991.2:c.303+10180G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.633,\N,\N,TSPEAR
506208,21:45977489:C>T,NM_144991.2:c.303+10180G>A,\N,\N,2/11,Benign,\N,intron_variant,1.455,0.0061,1KG_AFR_AF,TSPEAR
506209,21:45977491:C>A,NM_144991.2:c.303+10178G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,7.404,\N,\N,TSPEAR
506210,21:45977500:G>GCAGGAGAACCCCACAA,NM_144991.2:c.303+10153_303+10168dup,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
506211,21:45977512:C>T,NM_144991.2:c.303+10157G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.176,\N,\N,TSPEAR
506212,21:45977524:C>A,NM_144991.2:c.303+10145G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,6.354,\N,\N,TSPEAR
506213,21:45977531:C>A,NM_144991.2:c.303+10138G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,6.41,\N,\N,TSPEAR
506214,21:45977542:C>T,NM_144991.2:c.303+10127G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,5.601,\N,\N,TSPEAR
506215,21:45977550:C>T,NM_144991.2:c.303+10119G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.008,\N,\N,TSPEAR
506216,21:45977555:G>A,NM_144991.2:c.303+10114C>T,\N,\N,2/11,Benign,\N,intron_variant,2.299,0.0139,1KG_EUR_AF,TSPEAR
506217,21:45977577:A>G,NM_144991.2:c.303+10092T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,5.976,0.001,1KG_EUR_AF,TSPEAR
506218,21:45977590:C>A,NM_144991.2:c.303+10079G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,8.145,\N,\N,TSPEAR
506219,21:45977613:C>T,NM_144991.2:c.303+10056G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,5.616,0.0014,1KG_AMR_AF,TSPEAR
506220,21:45977617:C>T,NM_144991.2:c.303+10052G>A,\N,\N,2/11,Benign,\N,intron_variant,2.434,0.031,1KG_AFR_AF,TSPEAR
506221,21:45977618:G>A,NM_144991.2:c.303+10051C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.304,0.001,1KG_EAS_AF,TSPEAR
506222,21:45977622:C>T,NM_144991.2:c.303+10047G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,5.095,0.001,1KG_EAS_AF,TSPEAR
506223,21:45977623:G>A,NM_144991.2:c.303+10046C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.348,0.001,1KG_SAS_AF,TSPEAR
506224,21:45977640:A>G,NM_144991.2:c.303+10029T>C,\N,\N,2/11,Benign,\N,intron_variant,1.321,0.3929,1KG_EAS_AF,TSPEAR
506225,21:45977668:T>C,NM_144991.2:c.303+10001A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,2.456,\N,\N,TSPEAR
506226,21:45977679:A>T,NM_144991.2:c.303+9990T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.672,0.0008,1KG_AFR_AF,TSPEAR
506227,21:45977699:T>C,NM_144991.2:c.303+9970A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,5.376,0.003,1KG_AFR_AF,TSPEAR
506228,21:45977717:C>T,NM_144991.2:c.303+9952G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,5.722,0.0008,1KG_AFR_AF,TSPEAR
506229,21:45977726:G>A,NM_144991.2:c.303+9943C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,6.314,0.0008,1KG_AFR_AF,TSPEAR
506230,21:45977727:G>A,NM_144991.2:c.303+9942C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,5.155,0.0008,1KG_AFR_AF,TSPEAR
506231,21:45977741:C>T,NM_144991.2:c.303+9928G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.592,\N,\N,TSPEAR
506232,21:45977742:G>A,NM_144991.2:c.303+9927C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.095,\N,\N,TSPEAR
506233,21:45977746:G>T,NM_144991.2:c.303+9923C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.075,\N,\N,TSPEAR
506234,21:45977790:G>A,NM_144991.2:c.303+9879C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,6.661,0.0014,1KG_AMR_AF,TSPEAR
506235,21:45977799:A>C,NM_144991.2:c.303+9870T>G,\N,\N,2/11,Benign,\N,intron_variant,3.448,0.006,1KG_EUR_AF,TSPEAR
506236,21:45977811:C>T,NM_144991.2:c.303+9858G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.181,0.0038,1KG_AFR_AF,TSPEAR
506237,21:45977828:G>T,NM_144991.2:c.303+9841C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.062,\N,\N,TSPEAR
506238,21:45977871:G>A,NM_144991.2:c.303+9798C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,4.261,0.0008,1KG_AFR_AF,TSPEAR
506239,21:45977882:C>T,NM_144991.2:c.303+9787G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.02,0.001,1KG_EAS_AF,TSPEAR
506240,21:45977883:G>A,NM_144991.2:c.303+9786C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,4.748,0.00046919,EXAC_FIN_AF,TSPEAR
506241,21:45977896:G>A,NM_144991.2:c.303+9773C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,6.558,0.000117426,EVS_EA_AF,TSPEAR
506242,21:45977899:C>G,NM_144991.2:c.303+9770G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,5.876,0.000107135,EXAC_AFR_AF,TSPEAR
506243,21:45977902:G>A,NM_144991.2:c.303+9767C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,5.876,0.000236574,EXAC_EAS_AF,TSPEAR
506244,21:45977918:A>G,NM_198696.2:c.*15T>C,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,3.732,0.0000876271,EXAC_AMR_AF,TSPEAR
506245,21:45977920:C>T,NM_198696.2:c.*13G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,1.635,0.000206911,EXAC_SAS_AF,TSPEAR
506246,21:45977921:G>A,NM_198696.2:c.*12C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,1.984,0.000308071,EXAC_FIN_AF,TSPEAR
506247,21:45977925:C>A,NM_198696.2:c.*8G>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,7.122,0.0000313362,EXAC_NFE_AF,TSPEAR
506248,21:45977925:C>T,NM_198696.2:c.*8G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,6.923,0.000821211,EXAC_EAS_AF,TSPEAR
506249,21:45977928:G>A,NM_198696.2:c.*5C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,10.78,0.002,1KG_EAS_AF,TSPEAR
506250,21:45977931:C>T,NM_198696.2:c.*2G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,9.551,0.0008,1KG_AFR_AF,TSPEAR
506251,21:45977932:G>A,NM_198696.2:c.*1C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,7.712,0.000233863,EXAC_EAS_AF,TSPEAR
506252,21:45977932:G>T,NM_198696.2:c.*1C>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,6.473,0.000105396,EXAC_AFR_AF,TSPEAR
506253,21:45977935:A>T,NM_198696.2:c.664T>A,NP_941969.2:p.Ter222ArgextTer?,1/1,\N,Unknown significance,\N,stop_lost,18.91,0.000105086,EXAC_AFR_AF,TSPEAR
506254,21:45977945:C>T,NM_198696.2:c.654G>A,NP_941969.2:p.Lys218=,1/1,\N,Benign,\N,synonymous_variant,10.55,0.0214738,EVS_EA_AF,TSPEAR
506255,21:45977954:T>G,NM_198696.2:c.645A>C,NP_941969.2:p.Ser215=,1/1,\N,Unknown significance,\N,synonymous_variant,0.193,0.00120192,EXAC_OTH_AF,TSPEAR
506256,21:45977955:G>A,NM_198696.2:c.644C>T,NP_941969.2:p.Ser215Leu,1/1,\N,Likely benign,\N,missense_variant,18.18,0.000117288,EVS_EA_AF,TSPEAR
506257,21:45977957:G>T,NM_198696.2:c.642C>A,NP_941969.2:p.Ser214=,1/1,\N,Unknown significance,\N,synonymous_variant,0.411,0.0015,1KG_AFR_AF,TSPEAR
506258,21:45977965:C>T,NM_198696.2:c.634G>A,NP_941969.2:p.Gly212Ser,1/1,\N,Likely benign,\N,missense_variant,2.555,0.001,1KG_EUR_AF,TSPEAR
506259,21:45977966:G>A,NM_198696.2:c.633C>T,NP_941969.2:p.Cys211=,1/1,\N,Unknown significance,\N,synonymous_variant,0.979,0.000459348,EVS_AA_AF,TSPEAR
506260,21:45977967:C>T,NM_198696.2:c.632G>A,NP_941969.2:p.Cys211Tyr,1/1,\N,Likely benign,\N,missense_variant,1.741,0.000117261,EVS_EA_AF,TSPEAR
506261,21:45977968:A>G,NM_198696.2:c.631T>C,NP_941969.2:p.Cys211Arg,1/1,\N,Unknown significance,\N,missense_variant,23.6,\N,\N,TSPEAR
506262,21:45977969:G>GCAC,NM_198696.2:c.627_629dup,NP_941969.2:p.Ala209_Cys210insTrp,1/1,\N,Unknown significance,\N,inframe_insertion,7.431,0.0000705716,EXAC_SAS_AF,TSPEAR
506263,21:45977970:C>A,NM_198696.2:c.629G>T,NP_941969.2:p.Cys210Phe,1/1,\N,Unknown significance,\N,missense_variant,25.3,0.0000866852,EXAC_AMR_AF,TSPEAR
506264,21:45977972:C>T,NM_198696.2:c.627G>A,NP_941969.2:p.Ala209=,1/1,\N,Benign,\N,synonymous_variant,13.04,0.0182,1KG_AFR_AF,TSPEAR
506265,21:45977973:G>A,NM_198696.2:c.626C>T,NP_941969.2:p.Ala209Val,1/1,\N,Benign,\N,missense_variant,24,0.0265,1KG_AFR_AF,TSPEAR
506266,21:45977974:C>T,NM_198696.2:c.625G>A,NP_941969.2:p.Ala209Thr,1/1,\N,Unknown significance,\N,missense_variant,25.1,0.0014,1KG_AMR_AF,TSPEAR
506267,21:45977975:G>A,NM_198696.2:c.624C>T,NP_941969.2:p.Ser208=,1/1,\N,Unknown significance,\N,synonymous_variant,6.742,0.00114679,EXAC_OTH_AF,TSPEAR
506268,21:45977978:A>G,NM_198696.2:c.621T>C,NP_941969.2:p.Ser207=,1/1,\N,Unknown significance,\N,synonymous_variant,0.049,0.000066454,EXAC_SAS_AF,TSPEAR
506269,21:45977979:G>C,NM_198696.2:c.620C>G,NP_941969.2:p.Ser207Cys,1/1,\N,Likely benign,\N,missense_variant,18.74,0.00256112,EXAC_EAS_AF,TSPEAR
506270,21:45977983:G>A,NM_198696.2:c.616C>T,NP_941969.2:p.Leu206Phe,1/1,\N,Unknown significance,\N,missense_variant,13.73,0.000116279,EXAC_EAS_AF,TSPEAR
506271,21:45977984:G>T,NM_198696.2:c.615C>A,NP_941969.2:p.Arg205=,1/1,\N,Unknown significance,\N,synonymous_variant,0.173,0.0000659544,EXAC_SAS_AF,TSPEAR
506272,21:45977985:C>T,NM_198696.2:c.614G>A,NP_941969.2:p.Arg205His,1/1,\N,Likely benign,\N,missense_variant,22.5,\N,\N,TSPEAR
506273,21:45977986:G>A,NM_198696.2:c.613C>T,NP_941969.2:p.Arg205Cys,1/1,\N,Likely benign,\N,missense_variant,20.2,0.0000152286,EXAC_NFE_AF,TSPEAR
506274,21:45977993:C>T,NM_198696.2:c.606G>A,NP_941969.2:p.Thr202=,1/1,\N,Unknown significance,\N,synonymous_variant,12.09,0.00137112,EXAC_FIN_AF,TSPEAR
506275,21:45977994:G>A,NM_198696.2:c.605C>T,NP_941969.2:p.Thr202Met,1/1,\N,Likely benign,\N,missense_variant,0.115,0.001,1KG_EAS_AF,TSPEAR
506276,21:45977995:T>C,NM_198696.2:c.604A>G,NP_941969.2:p.Thr202Ala,1/1,\N,Benign,\N,missense_variant,0.001,0.0431,1KG_AFR_AF,TSPEAR
506277,21:45978000:C>T,NM_198696.2:c.599G>A,NP_941969.2:p.Arg200His,1/1,\N,Unknown significance,\N,missense_variant,23.4,0.000227687,EVS_AA_AF,TSPEAR
506278,21:45978001:G>A,NM_198696.2:c.598C>T,NP_941969.2:p.Arg200Cys,1/1,\N,Unknown significance,\N,missense_variant,32,0.001,1KG_EAS_AF,TSPEAR
506279,21:45978007:G>A,NM_198696.2:c.592C>T,NP_941969.2:p.Leu198Phe,1/1,\N,Unknown significance,\N,missense_variant,24.8,0.0000151488,EXAC_NFE_AF,TSPEAR
506280,21:45978007:G>C,NM_198696.2:c.592C>G,NP_941969.2:p.Leu198Val,1/1,\N,Unknown significance,\N,missense_variant,22.9,0.0008,1KG_AFR_AF,TSPEAR
506281,21:45978012:G>C,NM_198696.2:c.587C>G,NP_941969.2:p.Ser196Cys,1/1,\N,Unknown significance,\N,missense_variant,25.7,0.001,1KG_EUR_AF,TSPEAR
506282,21:45978015:A>C,NM_198696.2:c.584T>G,NP_941969.2:p.Val195Gly,1/1,\N,Unknown significance,\N,missense_variant,25.5,0.000086881,EXAC_AMR_AF,TSPEAR
506283,21:45978016:C>G,NM_198696.2:c.583G>C,NP_941969.2:p.Val195Leu,1/1,\N,Unknown significance,\N,missense_variant,25.1,0.00214225,EXAC_SAS_AF,TSPEAR
506284,21:45978016:C>T,NM_198696.2:c.583G>A,NP_941969.2:p.Val195Met,1/1,\N,Unknown significance,\N,missense_variant,25.3,0.00356894,EXAC_AMR_AF,TSPEAR
506285,21:45978017:G>A,NM_198696.2:c.582C>T,NP_941969.2:p.Cys194=,1/1,\N,Unknown significance,\N,synonymous_variant,13.22,0.000261097,EXAC_AMR_AF,TSPEAR
506286,21:45978021:G>C,NM_198696.2:c.578C>G,NP_941969.2:p.Ser193Cys,1/1,\N,Unknown significance,\N,missense_variant,23.3,0.000116333,EVS_EA_AF,TSPEAR
506287,21:45978026:C>T,NM_198696.2:c.573G>A,NP_941969.2:p.Pro191=,1/1,\N,Unknown significance,\N,synonymous_variant,13.56,0.001,1KG_SAS_AF,TSPEAR
506288,21:45978027:G>A,NM_198696.2:c.572C>T,NP_941969.2:p.Pro191Leu,1/1,\N,Unknown significance,\N,missense_variant,21.9,0.000227169,EVS_AA_AF,TSPEAR
506289,21:45978028:G>C,NM_198696.2:c.571C>G,NP_941969.2:p.Pro191Ala,1/1,\N,Unknown significance,\N,missense_variant,10.39,0.00011636,EVS_EA_AF,TSPEAR
506290,21:45978028:G>T,NM_198696.2:c.571C>A,NP_941969.2:p.Pro191Thr,1/1,\N,Unknown significance,\N,missense_variant,11.15,0.00224719,EXAC_OTH_AF,TSPEAR
506291,21:45978030:C>T,NM_198696.2:c.569G>A,NP_941969.2:p.Arg190His,1/1,\N,Unknown significance,\N,missense_variant,19.16,0.000117371,EXAC_EAS_AF,TSPEAR
506292,21:45978031:G>A,NM_198696.2:c.568C>T,NP_941969.2:p.Arg190Cys,1/1,\N,Unknown significance,\N,missense_variant,23.7,0.001,1KG_EAS_AF,TSPEAR
506293,21:45978032:G>A,NM_198696.2:c.567C>T,NP_941969.2:p.Cys189=,1/1,\N,Unknown significance,\N,synonymous_variant,1.521,0.0000870474,EXAC_AMR_AF,TSPEAR
506294,21:45978033:C>T,NM_198696.2:c.566G>A,NP_941969.2:p.Cys189Tyr,1/1,\N,Unknown significance,\N,missense_variant,23.8,0.0000151185,EXAC_NFE_AF,TSPEAR
506295,21:45978034:A>G,NM_198696.2:c.565T>C,NP_941969.2:p.Cys189Arg,1/1,\N,Unknown significance,\N,missense_variant,23.4,0.0000870474,EXAC_AMR_AF,TSPEAR
506296,21:45978038:G>A,NM_198696.2:c.561C>T,NP_941969.2:p.Ser187=,1/1,\N,Unknown significance,\N,synonymous_variant,0.125,0.0000608199,EXAC_SAS_AF,TSPEAR
506297,21:45978043:G>A,NM_198696.2:c.556C>T,NP_941969.2:p.Pro186Ser,1/1,\N,Likely benign,\N,missense_variant,0.236,0.001,1KG_EAS_AF,TSPEAR
506298,21:45978043:G>C,NM_198696.2:c.556C>G,NP_941969.2:p.Pro186Ala,1/1,\N,Unknown significance,\N,missense_variant,4.933,0.000232666,EVS_EA_AF,TSPEAR
506299,21:45978044:C>T,NM_198696.2:c.555G>A,NP_941969.2:p.Gln185=,1/1,\N,Unknown significance,\N,synonymous_variant,3.222,0.000256821,EXAC_NFE_AF,TSPEAR
506300,21:45978048:C>T,NM_198696.2:c.551G>A,NP_941969.2:p.Cys184Tyr,1/1,\N,Unknown significance,\N,missense_variant,24.6,0.001,1KG_SAS_AF,TSPEAR
506301,21:45978050:G>A,NM_198696.2:c.549C>T,NP_941969.2:p.Thr183=,1/1,\N,Unknown significance,\N,synonymous_variant,0.61,0.000117096,EXAC_EAS_AF,TSPEAR
506302,21:45978051:G>A,NM_198696.2:c.548C>T,NP_941969.2:p.Thr183Ile,1/1,\N,Likely benign,\N,missense_variant,0.547,\N,\N,TSPEAR
506303,21:45978052:T>A,NM_198696.2:c.547A>T,NP_941969.2:p.Thr183Ser,1/1,\N,Likely benign,\N,missense_variant,0.001,0.001,1KG_EAS_AF|1KG_SAS_AF,TSPEAR
506304,21:45978052:T>G,NM_198696.2:c.547A>C,NP_941969.2:p.Thr183Pro,1/1,\N,Likely benign,\N,missense_variant,0.024,\N,\N,TSPEAR
506305,21:45978054:G>A,NM_198696.2:c.545C>T,NP_941969.2:p.Ser182Phe,1/1,\N,Unknown significance,\N,missense_variant,22.8,0.000405268,EXAC_AFR_AF,TSPEAR
506306,21:45978058:C>T,NM_198696.2:c.541G>A,NP_941969.2:p.Ala181Thr,1/1,\N,Likely benign,\N,missense_variant,0.001,0.001,1KG_EAS_AF,TSPEAR
506307,21:45978059:A>G,NM_198696.2:c.540T>C,NP_941969.2:p.Pro180=,1/1,\N,Unknown significance,\N,synonymous_variant,0.019,0.001,1KG_EAS_AF,TSPEAR
506308,21:45978061:G>A,NM_198696.2:c.538C>T,NP_941969.2:p.Pro180Ser,1/1,\N,Likely benign,\N,missense_variant,2.034,\N,\N,TSPEAR
506309,21:45978062:G>A,NM_198696.2:c.537C>T,NP_941969.2:p.Ala179=,1/1,\N,Unknown significance,\N,synonymous_variant,0.873,0.0000150566,EXAC_NFE_AF,TSPEAR
506310,21:45978063:G>A,NM_198696.2:c.536C>T,NP_941969.2:p.Ala179Val,1/1,\N,Likely benign,\N,missense_variant,10.22,0.0000150548,EXAC_NFE_AF,TSPEAR
506311,21:45978063:G>T,NM_198696.2:c.536C>A,NP_941969.2:p.Ala179Asp,1/1,\N,Unknown significance,\N,missense_variant,20.5,0.0000150548,EXAC_NFE_AF,TSPEAR
506312,21:45978065:A>G,NM_198696.2:c.534T>C,NP_941969.2:p.Cys178=,1/1,\N,Unknown significance,\N,synonymous_variant,0.005,0.0000868659,EXAC_AMR_AF,TSPEAR
506313,21:45978066:C>T,NM_198696.2:c.533G>A,NP_941969.2:p.Cys178Tyr,1/1,\N,Unknown significance,\N,missense_variant,15.84,\N,\N,TSPEAR
506314,21:45978067:A>C,NM_198696.2:c.532T>G,NP_941969.2:p.Cys178Gly,1/1,\N,Unknown significance,\N,missense_variant,0.208,0.0000300969,EXAC_NFE_AF,TSPEAR
506315,21:45978076:G>A,NM_198696.2:c.523C>T,NP_941969.2:p.Pro175Ser,1/1,\N,Likely benign,\N,missense_variant,0.001,0.002,1KG_SAS_AF,TSPEAR
506316,21:45978078:A>T,NM_198696.2:c.521T>A,NP_941969.2:p.Ile174Asn,1/1,\N,Likely benign,\N,missense_variant,13.59,0.000116306,EVS_EA_AF,TSPEAR
506317,21:45978079:T>C,NM_198696.2:c.520A>G,NP_941969.2:p.Ile174Val,1/1,\N,Benign,\N,missense_variant,0.001,0.0061,1KG_SAS_AF,TSPEAR
506318,21:45978080:G>A,NM_198696.2:c.519C>T,NP_941969.2:p.Pro173=,1/1,\N,Unknown significance,\N,synonymous_variant,0.427,0.0000300508,EXAC_NFE_AF,TSPEAR
506319,21:45978081:G>C,NM_198696.2:c.518C>G,NP_941969.2:p.Pro173Arg,1/1,\N,Unknown significance,\N,missense_variant,22.4,0.0000991473,EXAC_AFR_AF,TSPEAR
506320,21:45978085:C>T,NM_198696.2:c.514G>A,NP_941969.2:p.Val172Met,1/1,\N,Likely benign,\N,missense_variant,18.66,0.0000300391,EXAC_NFE_AF,TSPEAR
506321,21:45978086:A>G,NM_198696.2:c.513T>C,NP_941969.2:p.Cys171=,1/1,\N,Unknown significance,\N,synonymous_variant,0.002,0.0014,1KG_AMR_AF,TSPEAR
506322,21:45978089:G>A,NM_198696.2:c.510C>T,NP_941969.2:p.Cys170=,1/1,\N,Unknown significance,\N,synonymous_variant,0.524,\N,\N,TSPEAR
506323,21:45978090:C>G,NM_198696.2:c.509G>C,NP_941969.2:p.Cys170Ser,1/1,\N,Likely benign,\N,missense_variant,15.19,0.0000149952,EXAC_NFE_AF,TSPEAR
506324,21:45978090:C>T,NM_198696.2:c.509G>A,NP_941969.2:p.Cys170Tyr,1/1,\N,Benign,\N,missense_variant,22.9,0.962016,EXAC_FIN_AF,TSPEAR
506325,21:45978094:T>C,NM_198696.2:c.505A>G,NP_941969.2:p.Thr169Ala,1/1,\N,Likely benign,\N,missense_variant,0.001,0.0008,1KG_AFR_AF,TSPEAR
506326,21:45978097:A>G,NM_198696.2:c.502T>C,NP_941969.2:p.Ser168Pro,1/1,\N,Likely benign,\N,missense_variant,0.006,0.0014,1KG_AMR_AF,TSPEAR
506327,21:45978099:C>T,NM_198696.2:c.500G>A,NP_941969.2:p.Arg167Lys,1/1,\N,Likely benign,\N,missense_variant,9.038,0.0000970309,EXAC_AFR_AF,TSPEAR
506328,21:45978106:C>G,NM_198696.2:c.493G>C,NP_941969.2:p.Val165Leu,1/1,\N,Unknown significance,\N,missense_variant,21.7,0.0000605914,EXAC_SAS_AF,TSPEAR
506329,21:45978106:C>T,NM_198696.2:c.493G>A,NP_941969.2:p.Val165Met,1/1,\N,Unknown significance,\N,missense_variant,22.3,0.0000149961,EXAC_NFE_AF,TSPEAR
506330,21:45978107:G>A,NM_198696.2:c.492C>T,NP_941969.2:p.Pro164=,1/1,\N,Unknown significance,\N,synonymous_variant,4.274,0.000194099,EXAC_AFR_AF,TSPEAR
506331,21:45978108:G>C,NM_198696.2:c.491C>G,NP_941969.2:p.Pro164Arg,1/1,\N,Unknown significance,\N,missense_variant,14.43,0.000231857,EXAC_EAS_AF,TSPEAR
506332,21:45978111:C>T,NM_198696.2:c.488G>A,NP_941969.2:p.Arg163His,1/1,\N,Likely benign,\N,missense_variant,14.55,0.001,1KG_EAS_AF,TSPEAR
506333,21:45978112:G>A,NM_198696.2:c.487C>T,NP_941969.2:p.Arg163Cys,1/1,\N,Likely benign,\N,missense_variant,19.85,0.000226963,EVS_AA_AF,TSPEAR
506334,21:45978117:A>G,NM_198696.2:c.482T>C,NP_941969.2:p.Leu161Pro,1/1,\N,Unknown significance,\N,missense_variant,15.45,\N,\N,TSPEAR
506335,21:45978127:C>T,NM_198696.2:c.472G>A,NP_941969.2:p.Val158Met,1/1,\N,Likely benign,\N,missense_variant,13.11,0.000226963,EVS_AA_AF,TSPEAR
506336,21:45978128:G>A,NM_198696.2:c.471C>T,NP_941969.2:p.Ser157=,1/1,\N,Benign,\N,synonymous_variant,6.285,0.0596913,EVS_AA_AF,TSPEAR
506337,21:45978131:G>A,NM_198696.2:c.468C>T,NP_941969.2:p.Ser156=,1/1,\N,Unknown significance,\N,synonymous_variant,1.047,\N,\N,TSPEAR
506338,21:45978136:A>T,NM_198696.2:c.463T>A,NP_941969.2:p.Ser155Thr,1/1,\N,Unknown significance,\N,missense_variant,2.726,0.001,1KG_SAS_AF,TSPEAR
506339,21:45978138:G>A,NM_198696.2:c.461C>T,NP_941969.2:p.Pro154Leu,1/1,\N,Unknown significance,\N,missense_variant,20.6,0.0000149898,EXAC_NFE_AF,TSPEAR
506340,21:45978139:G>A,NM_198696.2:c.460C>T,NP_941969.2:p.Pro154Ser,1/1,\N,Unknown significance,\N,missense_variant,11.99,0.000231589,EXAC_EAS_AF,TSPEAR
506341,21:45978140:T>G,NM_198696.2:c.459A>C,NP_941969.2:p.Arg153Ser,1/1,\N,Likely benign,\N,missense_variant,13.89,0.0000149907,EXAC_NFE_AF,TSPEAR
506342,21:45978143:G>A,NM_198696.2:c.456C>T,NP_941969.2:p.Cys152=,1/1,\N,Unknown significance,\N,synonymous_variant,0.474,0.0000149903,EXAC_NFE_AF,TSPEAR
506343,21:45978144:C>T,NM_198696.2:c.455G>A,NP_941969.2:p.Cys152Tyr,1/1,\N,Unknown significance,\N,missense_variant,22,0.0000967492,EXAC_AFR_AF,TSPEAR
506344,21:45978145:A>C,NM_198696.2:c.454T>G,NP_941969.2:p.Cys152Gly,1/1,\N,Unknown significance,\N,missense_variant,14.54,0.000121124,EXAC_SAS_AF,TSPEAR
506345,21:45978154:T>C,NM_198696.2:c.445A>G,NP_941969.2:p.Thr149Ala,1/1,\N,Likely benign,\N,missense_variant,0.001,0.000193311,EXAC_AFR_AF,TSPEAR
506346,21:45978159:C>T,NM_198696.2:c.440G>A,NP_941969.2:p.Cys147Tyr,1/1,\N,Likely benign,\N,missense_variant,13.63,0.000193199,EXAC_AFR_AF,TSPEAR
506347,21:45978167:C>A,NM_198696.2:c.432G>T,NP_941969.2:p.Pro144=,1/1,\N,Unknown significance,\N,synonymous_variant,13.33,0.0000605694,EXAC_SAS_AF,TSPEAR
506348,21:45978167:C>T,NM_198696.2:c.432G>A,NP_941969.2:p.Pro144=,1/1,\N,Unknown significance,\N,synonymous_variant,12.57,0.0014,1KG_AMR_AF,TSPEAR
506349,21:45978168:G>A,NM_198696.2:c.431C>T,NP_941969.2:p.Pro144Leu,1/1,\N,Unknown significance,\N,missense_variant,20.7,0.000232558,EVS_EA_AF,TSPEAR
506350,21:45978173:G>A,NM_198696.2:c.426C>T,NP_941969.2:p.Arg142=,1/1,\N,Unknown significance,\N,synonymous_variant,6.187,\N,\N,TSPEAR
506351,21:45978174:C>A,NM_198696.2:c.425G>T,NP_941969.2:p.Arg142Leu,1/1,\N,Unknown significance,\N,missense_variant,25.5,0.0000605694,EXAC_SAS_AF,TSPEAR
506352,21:45978174:C>G,NM_198696.2:c.425G>C,NP_941969.2:p.Arg142Pro,1/1,\N,Benign,\N,missense_variant,24.9,0.00869397,EXAC_AFR_AF,TSPEAR
506353,21:45978174:C>T,NM_198696.2:c.425G>A,NP_941969.2:p.Arg142His,1/1,\N,Unknown significance,\N,missense_variant,25.5,0.000604699,EXAC_AMR_AF,TSPEAR
506354,21:45978175:G>A,NM_198696.2:c.424C>T,NP_941969.2:p.Arg142Cys,1/1,\N,Likely benign,\N,missense_variant,16.74,0.00340599,EVS_AA_AF,TSPEAR
506355,21:45978176:G>A,NM_198696.2:c.423C>T,NP_941969.2:p.Ser141=,1/1,\N,Unknown significance,\N,synonymous_variant,9.382,\N,\N,TSPEAR
506356,21:45978180:G>C,NM_198696.2:c.419C>G,NP_941969.2:p.Ser140Cys,1/1,\N,Unknown significance,\N,missense_variant,21.6,0.000839152,EXAC_NFE_AF,TSPEAR
506357,21:45978181:A>G,NM_198696.2:c.418T>C,NP_941969.2:p.Ser140Pro,1/1,\N,Unknown significance,\N,missense_variant,19.38,0.0000149849,EXAC_NFE_AF,TSPEAR
506358,21:45978193:A>G,NM_198696.2:c.406T>C,NP_941969.2:p.Cys136Arg,1/1,\N,Unknown significance,\N,missense_variant,17.97,0.0000299715,EXAC_NFE_AF,TSPEAR
506359,21:45978194:T>C,NM_198696.2:c.405A>G,NP_941969.2:p.Ser135=,1/1,\N,Unknown significance,\N,synonymous_variant,0.092,\N,\N,TSPEAR
506360,21:45978195:G>A,NM_198696.2:c.404C>T,NP_941969.2:p.Ser135Leu,1/1,\N,Unknown significance,\N,missense_variant,6.705,\N,\N,TSPEAR
506361,21:45978196:A>G,NM_198696.2:c.403T>C,NP_941969.2:p.Ser135Pro,1/1,\N,Likely benign,\N,missense_variant,5.64,\N,\N,TSPEAR
506362,21:45978200:G>A,NM_198696.2:c.399C>T,NP_941969.2:p.Ser133=,1/1,\N,Unknown significance,\N,synonymous_variant,1.084,0.000302883,EXAC_SAS_AF,TSPEAR
506363,21:45978207:C>T,NM_198696.2:c.392G>A,NP_941969.2:p.Gly131Glu,1/1,\N,Likely benign,\N,missense_variant,0.005,0.000115607,EXAC_EAS_AF,TSPEAR
506364,21:45978208:C>T,NM_198696.2:c.391G>A,NP_941969.2:p.Gly131Arg,1/1,\N,Likely benign,\N,missense_variant,8.479,0.000116279,EVS_EA_AF,TSPEAR
506365,21:45978209:AGAGCAGACGGGCACACAGCAGATGGGCTTGCAGCAGACAGGCTTG>A,NM_198696.2:c.345_389del,NP_941969.2:p.Lys116_Ser130del,1/1,\N,Unknown significance,\N,inframe_deletion,12.79,\N,\N,TSPEAR
506366,21:45978210:G>C,NM_198696.2:c.389C>G,NP_941969.2:p.Ser130Cys,1/1,\N,Likely benign,\N,missense_variant,5.037,0.000465116,EVS_EA_AF,TSPEAR
506367,21:45978210:GAGCAGACGGGCACACAGCAGATGGGCTTGCAGCAGACAGGCTTGC>G,NM_198696.2:c.344_388del,NP_941969.2:p.Cys115_Cys129del,1/1,\N,Unknown significance,\N,inframe_deletion,12.89,\N,\N,TSPEAR
506368,21:45978217:C>T,NM_198696.2:c.382G>A,NP_941969.2:p.Val128Ile,1/1,\N,Likely benign,\N,missense_variant,0.027,0.0000599538,EXAC_NFE_AF,TSPEAR
506369,21:45978218:G>A,NM_198696.2:c.381C>T,NP_941969.2:p.Pro127=,1/1,\N,Unknown significance,\N,synonymous_variant,3.238,0.00302663,EXAC_FIN_AF,TSPEAR
506370,21:45978223:C>T,NM_198696.2:c.376G>A,NP_941969.2:p.Val126Met,1/1,\N,Likely benign,\N,missense_variant,6.989,0.000116279,EVS_EA_AF,TSPEAR
506371,21:45978224:ACAGCAGATGGGCTTG>A,NM_198696.2:c.360_374del,NP_941969.2:p.Lys121_Cys125del,1/1,\N,Unknown significance,\N,inframe_deletion,13.32,\N,\N,TSPEAR
506372,21:45978224:ACAGCAGATGGGCTTGCAGCAGACAGGCTTG>A,NM_198696.2:c.345_374del,NP_941969.2:p.Lys116_Cys125del,1/1,\N,Unknown significance,\N,inframe_deletion,14.08,\N,\N,TSPEAR
506373,21:45978225:C>T,NM_198696.2:c.374G>A,NP_941969.2:p.Cys125Tyr,1/1,\N,Likely benign,\N,missense_variant,19.55,0.0000149867,EXAC_NFE_AF,TSPEAR
506374,21:45978228:C>T,NM_198696.2:c.371G>A,NP_941969.2:p.Cys124Tyr,1/1,\N,Benign,\N,missense_variant,18.92,0.00543353,EXAC_EAS_AF,TSPEAR
506375,21:45978230:G>C,NM_198696.2:c.369C>G,NP_941969.2:p.Ile123Met,1/1,\N,Likely benign,\N,missense_variant,0.673,\N,\N,TSPEAR
506376,21:45978232:T>C,NM_198696.2:c.367A>G,NP_941969.2:p.Ile123Val,1/1,\N,Likely benign,\N,missense_variant,0.001,0.0015,1KG_AFR_AF,TSPEAR
506377,21:45978233:G>C,NM_198696.2:c.366C>G,NP_941969.2:p.Pro122=,1/1,\N,Unknown significance,\N,synonymous_variant,0.015,0.000116279,EVS_EA_AF,TSPEAR
506378,21:45978233:G>T,NM_198696.2:c.366C>A,NP_941969.2:p.Pro122=,1/1,\N,Unknown significance,\N,synonymous_variant,0.013,0.0015,1KG_AFR_AF,TSPEAR
506379,21:45978233:GGGCTTGCAGCAGACA>G,NM_198696.2:c.351_365del,NP_941969.2:p.Val118_Pro122del,1/1,\N,Unknown significance,\N,inframe_deletion,13.44,\N,\N,TSPEAR
506380,21:45978233:GGGCTTGCAGCAGACAGGCTTGCAGCAGACGGGCACACAGCAGACT>G,NM_198696.2:c.321_365del,NP_941969.2:p.Val108_Pro122del,1/1,\N,Unknown significance,\N,inframe_deletion,12.67,\N,\N,TSPEAR
506381,21:45978236:C>T,NM_198696.2:c.363G>A,NP_941969.2:p.Lys121=,1/1,\N,Unknown significance,\N,synonymous_variant,7.613,0.000116279,EVS_EA_AF,TSPEAR
506382,21:45978239:G>A,NM_198696.2:c.360C>T,NP_941969.2:p.Cys120=,1/1,\N,Unknown significance,\N,synonymous_variant,0.56,\N,\N,TSPEAR
506383,21:45978239:GCAGCAGACAGGCTTGCAGCAGACGGGCACA>G,NM_198696.2:c.330_359del,NP_941969.2:p.Val111_Cys120del,1/1,\N,Unknown significance,\N,inframe_deletion,13.71,\N,\N,TSPEAR
506384,21:45978241:A>T,NM_198696.2:c.358T>A,NP_941969.2:p.Cys120Ser,1/1,\N,Unknown significance,\N,missense_variant,10.76,0.0000606061,EXAC_SAS_AF,TSPEAR
506385,21:45978248:AGGCTTGCAGCAGACGGGCACACAGCAGACT>A,NM_198696.2:c.321_350del,NP_941969.2:p.Val111_Cys120del,1/1,\N,Unknown significance,\N,inframe_deletion,13.78,\N,\N,TSPEAR
506386,21:45978252:T>A,NM_198696.2:c.347A>T,NP_941969.2:p.Lys116Met,1/1,\N,Likely benign,\N,missense_variant,7.678,0.003,1KG_AFR_AF,TSPEAR
506387,21:45978253:T>C,NM_198696.2:c.346A>G,NP_941969.2:p.Lys116Glu,1/1,\N,Likely benign,\N,missense_variant,2.792,0.003,1KG_AFR_AF,TSPEAR
506388,21:45978254:GCAGCAGACGGGCACA>G,NM_198696.2:c.330_344del,NP_941969.2:p.Val111_Cys115del,1/1,\N,Unknown significance,\N,inframe_deletion,12.32,\N,\N,TSPEAR
506389,21:45978257:G>T,NM_198696.2:c.342C>A,NP_941969.2:p.Cys114Ter,1/1,\N,Unknown significance,\N,stop_gained,36,0.0000149889,EXAC_NFE_AF,TSPEAR
506390,21:45978262:C>T,NM_198696.2:c.337G>A,NP_941969.2:p.Val113Ile,1/1,\N,Likely benign,\N,missense_variant,7.505,0.000060584,EXAC_SAS_AF,TSPEAR
506391,21:45978263:GGGCACACAGCAGACT>G,NM_198696.2:c.321_335del,NP_941969.2:p.Val111_Cys115del,1/1,\N,Unknown significance,\N,inframe_deletion,\N,\N,\N,TSPEAR
506392,21:45978263:GGGCACACAGCAGACTGGCTTGCAGCAGACA>G,NM_198696.2:c.306_335del,NP_941969.2:p.Val111_Cys120del,1/1,\N,Unknown significance,\N,inframe_deletion,12.74,\N,\N,TSPEAR
506393,21:45978264:G>C,NM_198696.2:c.335C>G,NP_941969.2:p.Pro112Arg,1/1,\N,Unknown significance,\N,missense_variant,12.54,0.0000449721,EXAC_NFE_AF,TSPEAR
506394,21:45978265:G>T,NM_198696.2:c.334C>A,NP_941969.2:p.Pro112Thr,1/1,\N,Unknown significance,\N,missense_variant,11.97,\N,\N,TSPEAR
506395,21:45978266:C>T,NM_198696.2:c.333G>A,NP_941969.2:p.Val111=,1/1,\N,Unknown significance,\N,synonymous_variant,8.252,0.000116279,EVS_EA_AF,TSPEAR
506396,21:45978269:A>G,NM_198696.2:c.330T>C,NP_941969.2:p.Cys110=,1/1,\N,Unknown significance,\N,synonymous_variant,0.006,0.0023,1KG_AFR_AF,TSPEAR
506397,21:45978269:ACAGCAGACTGGCTTG>A,NM_198696.2:c.315_329del,NP_941969.2:p.Lys106_Cys110del,1/1,\N,Unknown significance,\N,inframe_deletion,13.36,0.000462749,EXAC_EAS_AF,TSPEAR
506398,21:45978269:ACAGCAGACTGGCTTGCAGCAGACAGGCACG>A,NM_198696.2:c.300_329del,NP_941969.2:p.Val111_Cys120del,1/1,\N,Unknown significance,\N,inframe_deletion,12.6,0.000060584,EXAC_SAS_AF,TSPEAR
506399,21:45978270:C>G,NM_198696.2:c.329G>C,NP_941969.2:p.Cys110Ser,1/1,\N,Unknown significance,\N,missense_variant,10.06,0.0000449708,EXAC_NFE_AF,TSPEAR
506400,21:45978273:C>T,NM_198696.2:c.326G>A,NP_941969.2:p.Cys109Tyr,1/1,\N,Unknown significance,\N,missense_variant,15.03,0.0000967867,EXAC_AFR_AF,TSPEAR
506401,21:45978274:A>AGAC,NM_198696.2:c.322_324dup,NP_941969.2:p.Val108dup,1/1,\N,Unknown significance,\N,inframe_insertion,0.015,0.000014993,EXAC_NFE_AF,TSPEAR
506402,21:45978275:G>C,NM_198696.2:c.324C>G,NP_941969.2:p.Val108=,1/1,\N,Unknown significance,\N,synonymous_variant,1.639,0.00133301,EXAC_SAS_AF,TSPEAR
506403,21:45978277:C>T,NM_198696.2:c.322G>A,NP_941969.2:p.Val108Ile,1/1,\N,Likely benign,\N,missense_variant,9.247,0.001,1KG_EAS_AF,TSPEAR
506404,21:45978278:T>A,NM_198696.2:c.321A>T,NP_941969.2:p.Pro107=,1/1,\N,Unknown significance,\N,synonymous_variant,3.977,0.0023,1KG_AFR_AF,TSPEAR
506405,21:45978278:T>G,NM_198696.2:c.321A>C,NP_941969.2:p.Pro107=,1/1,\N,Unknown significance,\N,synonymous_variant,0.365,0.000347464,EXAC_EAS_AF,TSPEAR
506406,21:45978278:T>TGGCTTGCAGCAGACAGGCTTGCAGCAGACGGGCACACAGCACACA,NM_198696.2:c.320_321insTGTGTGCTGTGTGCCCGTCTGCTGCAAGCCTGTCTGCTGCAAGCC,NP_941969.2:p.Val108_Pro122dup,1/1,\N,Unknown significance,\N,inframe_insertion,1.139,0.000121183,EXAC_SAS_AF,TSPEAR
506407,21:45978280:G>T,NM_198696.2:c.319C>A,NP_941969.2:p.Pro107Thr,1/1,\N,Unknown significance,\N,missense_variant,13.07,0.0000968054,EXAC_AFR_AF,TSPEAR
506408,21:45978283:TGCAGCAGACAGGCAC>T,NM_198696.2:c.301_315del,NP_941969.2:p.Val101_Cys105del,1/1,\N,Unknown significance,\N,inframe_deletion,13.61,\N,\N,TSPEAR
506409,21:45978287:G>A,NM_198696.2:c.312C>T,NP_941969.2:p.Cys104=,1/1,\N,Unknown significance,\N,synonymous_variant,2.385,0.000014993,EXAC_NFE_AF,TSPEAR
506410,21:45978288:C>T,NM_198696.2:c.311G>A,NP_941969.2:p.Cys104Tyr,1/1,\N,Unknown significance,\N,missense_variant,21.9,0.000115741,EXAC_EAS_AF,TSPEAR
506411,21:45978292:C>T,NM_198696.2:c.307G>A,NP_941969.2:p.Val103Ile,1/1,\N,Likely benign,\N,missense_variant,3.363,0.0000605767,EXAC_SAS_AF,TSPEAR
506412,21:45978293:A>G,NM_198696.2:c.306T>C,NP_941969.2:p.Pro102=,1/1,\N,Unknown significance,\N,synonymous_variant,0.002,0.0015,1KG_AFR_AF,TSPEAR
506413,21:45978293:A>T,NM_198696.2:c.306T>A,NP_941969.2:p.Pro102=,1/1,\N,Unknown significance,\N,synonymous_variant,0.001,\N,\N,TSPEAR
506414,21:45978297:A>T,NM_198696.2:c.302T>A,NP_941969.2:p.Val101Glu,1/1,\N,Likely benign,\N,missense_variant,5.171,\N,\N,TSPEAR
506415,21:45978298:C>A,NM_198696.2:c.301G>T,NP_941969.2:p.Val101Leu,1/1,\N,Likely benign,\N,missense_variant,11.82,0.0000149984,EXAC_NFE_AF,TSPEAR
506416,21:45978298:C>T,NM_198696.2:c.301G>A,NP_941969.2:p.Val101Met,1/1,\N,Likely benign,\N,missense_variant,11.06,0.000604908,EXAC_AMR_AF,TSPEAR
506417,21:45978299:G>A,NM_198696.2:c.300C>T,NP_941969.2:p.Cys100=,1/1,\N,Unknown significance,\N,synonymous_variant,3.063,0.001,1KG_EAS_AF|1KG_SAS_AF,TSPEAR
506418,21:45978304:A>AGACG,NM_198696.2:c.294_295insCGTC,NP_941969.2:p.Cys99ArgfsTer44,1/1,\N,Unknown significance,\N,frameshift_variant,25.3,\N,\N,TSPEAR
506419,21:45978306:G>A,NM_198696.2:c.293C>T,NP_941969.2:p.Ala98Val,1/1,\N,Likely benign,\N,missense_variant,3.964,0.000232558,EVS_EA_AF,TSPEAR
506420,21:45978307:C>CA,NM_198696.2:c.291_292insT,NP_941969.2:p.Ala98CysfsTer44,1/1,\N,Unknown significance,\N,frameshift_variant,23.2,\N,\N,TSPEAR
506421,21:45978323:G>A,NM_198696.2:c.276C>T,NP_941969.2:p.Ser92=,1/1,\N,Unknown significance,\N,synonymous_variant,2.577,0.001,1KG_SAS_AF,TSPEAR
506422,21:45978326:T>G,NM_198696.2:c.273A>C,NP_941969.2:p.Thr91=,1/1,\N,Unknown significance,\N,synonymous_variant,3.594,\N,\N,TSPEAR
506423,21:45978333:C>T,NM_198696.2:c.266G>A,NP_941969.2:p.Cys89Tyr,1/1,\N,Unknown significance,\N,missense_variant,23.1,0.0014,1KG_AMR_AF,TSPEAR
506424,21:45978338:T>C,NM_198696.2:c.261A>G,NP_941969.2:p.Pro87=,1/1,\N,Unknown significance,\N,synonymous_variant,1.075,0.0014,1KG_AMR_AF,TSPEAR
506425,21:45978339:G>A,NM_198696.2:c.260C>T,NP_941969.2:p.Pro87Leu,1/1,\N,Likely benign,\N,missense_variant,15.98,\N,\N,TSPEAR
506426,21:45978341:C>T,NM_198696.2:c.258G>A,NP_941969.2:p.Gln86=,1/1,\N,Unknown significance,\N,synonymous_variant,9.594,0.000294753,EXAC_AFR_AF,TSPEAR
506427,21:45978345:C>T,NM_198696.2:c.254G>A,NP_941969.2:p.Cys85Tyr,1/1,\N,Unknown significance,\N,missense_variant,23.8,0.000232558,EVS_EA_AF,TSPEAR
506428,21:45978348:C>G,NM_198696.2:c.251G>C,NP_941969.2:p.Ser84Thr,1/1,\N,Unknown significance,\N,missense_variant,17.65,\N,\N,TSPEAR
506429,21:45978351:G>A,NM_198696.2:c.248C>T,NP_941969.2:p.Ser83Phe,1/1,\N,Unknown significance,\N,missense_variant,23.9,0.0000451467,EXAC_NFE_AF,TSPEAR
506430,21:45978356:C>T,NM_198696.2:c.243G>A,NP_941969.2:p.Gln81=,1/1,\N,Unknown significance,\N,synonymous_variant,11.55,0.000226963,EVS_AA_AF,TSPEAR
506431,21:45978358:G>A,NM_198696.2:c.241C>T,NP_941969.2:p.Gln81Ter,1/1,\N,Unknown significance,\N,stop_gained,36,0.0000867303,EXAC_AMR_AF,TSPEAR
506432,21:45978365:C>A,NM_198696.2:c.234G>T,NP_941969.2:p.Ser78=,1/1,\N,Unknown significance,\N,synonymous_variant,15.91,0.00110619,EXAC_OTH_AF,TSPEAR
506433,21:45978365:C>T,NM_198696.2:c.234G>A,NP_941969.2:p.Ser78=,1/1,\N,Unknown significance,\N,synonymous_variant,14.59,0.002,1KG_SAS_AF,TSPEAR
506434,21:45978366:G>A,NM_198696.2:c.233C>T,NP_941969.2:p.Ser78Leu,1/1,\N,Likely benign,\N,missense_variant,11.8,0.0014,1KG_AMR_AF,TSPEAR
506435,21:45978367:A>G,NM_198696.2:c.232T>C,NP_941969.2:p.Ser78Pro,1/1,\N,Likely benign,\N,missense_variant,8.777,0.000711238,EXAC_AFR_AF,TSPEAR
506436,21:45978370:G>A,NM_198696.2:c.229C>T,NP_941969.2:p.Pro77Ser,1/1,\N,Likely benign,\N,missense_variant,5.854,0.000227066,EVS_AA_AF,TSPEAR
506437,21:45978370:G>T,NM_198696.2:c.229C>A,NP_941969.2:p.Pro77Thr,1/1,\N,Likely benign,\N,missense_variant,11.08,0.0000151254,EXAC_NFE_AF,TSPEAR
506438,21:45978371:C>T,NM_198696.2:c.228G>A,NP_941969.2:p.Thr76=,1/1,\N,Unknown significance,\N,synonymous_variant,8.353,0.0000867754,EXAC_AMR_AF,TSPEAR
506439,21:45978372:G>A,NM_198696.2:c.227C>T,NP_941969.2:p.Thr76Met,1/1,\N,Benign,\N,missense_variant,13.65,0.0144,1KG_AFR_AF,TSPEAR
506440,21:45978374:G>A,NM_198696.2:c.225C>T,NP_941969.2:p.Cys75=,1/1,\N,Unknown significance,\N,synonymous_variant,6.794,0.000151515,EXAC_FIN_AF,TSPEAR
506441,21:45978381:C>T,NM_198696.2:c.218G>A,NP_941969.2:p.Ser73Asn,1/1,\N,Unknown significance,\N,missense_variant,21.2,0.002,1KG_SAS_AF,TSPEAR
506442,21:45978390:C>T,NM_198696.2:c.209G>A,NP_941969.2:p.Gly70Asp,1/1,\N,Likely benign,\N,missense_variant,3.725,0.00011636,EVS_EA_AF,TSPEAR
506443,21:45978395:C>T,NM_198696.2:c.204G>A,NP_941969.2:p.Gln68=,1/1,\N,Unknown significance,\N,synonymous_variant,6.118,\N,\N,TSPEAR
506444,21:45978397:GGCAGGGGCTGGGCTCACAGGCCGCCTGGCA>G,NM_198696.2:c.172_201del,NP_941969.2:p.Cys58_Cys67del,1/1,\N,Unknown significance,\N,inframe_deletion,14.9,\N,\N,TSPEAR
506445,21:45978400:A>G,NM_198696.2:c.199T>C,NP_941969.2:p.Cys67Arg,1/1,\N,Unknown significance,\N,missense_variant,20.3,\N,\N,TSPEAR
506446,21:45978403:G>C,NM_198696.2:c.196C>G,NP_941969.2:p.Pro66Ala,1/1,\N,Likely benign,\N,missense_variant,2.751,\N,\N,TSPEAR
506447,21:45978408:G>C,NM_198696.2:c.191C>G,NP_941969.2:p.Pro64Arg,1/1,\N,Unknown significance,\N,missense_variant,17.14,0.0000607903,EXAC_SAS_AF,TSPEAR
506448,21:45978414:C>T,NM_198696.2:c.185G>A,NP_941969.2:p.Cys62Tyr,1/1,\N,Likely benign,\N,missense_variant,20.4,0.0000152393,EXAC_NFE_AF,TSPEAR
506449,21:45978416:G>C,NM_198696.2:c.183C>G,NP_941969.2:p.Ala61=,1/1,\N,Unknown significance,\N,synonymous_variant,0.927,0.000853606,EXAC_AFR_AF,TSPEAR
506450,21:45978419:C>T,NM_198696.2:c.180G>A,NP_941969.2:p.Ala60=,1/1,\N,Unknown significance,\N,synonymous_variant,13.16,0.0015,1KG_AFR_AF,TSPEAR
506451,21:45978420:G>A,NM_198696.2:c.179C>T,NP_941969.2:p.Ala60Val,1/1,\N,Likely benign,\N,missense_variant,0.409,0.000117592,EXAC_EAS_AF,TSPEAR
506452,21:45978420:G>T,NM_198696.2:c.179C>A,NP_941969.2:p.Ala60Glu,1/1,\N,Likely benign,\N,missense_variant,4.771,0.0000152593,EXAC_NFE_AF,TSPEAR
506453,21:45978426:C>T,NM_198696.2:c.173G>A,NP_941969.2:p.Cys58Tyr,1/1,\N,Unknown significance,\N,missense_variant,13,0.0000152634,EXAC_NFE_AF,TSPEAR
506454,21:45978432:G>T,NM_198696.2:c.167C>A,NP_941969.2:p.Pro56His,1/1,\N,Unknown significance,\N,missense_variant,18.26,0.000107712,EXAC_AFR_AF,TSPEAR
506455,21:45978434:G>C,NM_198696.2:c.165C>G,NP_941969.2:p.Ser55Arg,1/1,\N,Likely benign,\N,missense_variant,15.84,0.000243398,EXAC_SAS_AF,TSPEAR
506456,21:45978440:C>T,NM_198696.2:c.159G>A,NP_941969.2:p.Val53=,1/1,\N,Unknown significance,\N,synonymous_variant,10.3,0.000117592,EXAC_EAS_AF,TSPEAR
506457,21:45978445:A>G,NM_198696.2:c.154T>C,NP_941969.2:p.Cys52Arg,1/1,\N,Benign,\N,missense_variant,16.64,0.0121,1KG_AFR_AF,TSPEAR
506458,21:45978447:C>T,NM_198696.2:c.152G>A,NP_941969.2:p.Ser51Asn,1/1,\N,Likely benign,\N,missense_variant,20.6,\N,\N,TSPEAR
506459,21:45978450:A>C,NM_198696.2:c.149T>G,NP_941969.2:p.Val50Gly,1/1,\N,Likely benign,\N,missense_variant,1.744,\N,\N,TSPEAR
506460,21:45978456:G>T,NM_198696.2:c.143C>A,NP_941969.2:p.Thr48Asn,1/1,\N,Likely benign,\N,missense_variant,16.23,\N,\N,TSPEAR
506461,21:45978458:G>A,NM_198696.2:c.141C>T,NP_941969.2:p.Cys47=,1/1,\N,Unknown significance,\N,synonymous_variant,1.988,0.001,1KG_EAS_AF,TSPEAR
506462,21:45978464:C>G,NM_198696.2:c.135G>C,NP_941969.2:p.Leu45=,1/1,\N,Unknown significance,\N,synonymous_variant,0.878,0.0000153214,EXAC_NFE_AF,TSPEAR
506463,21:45978467:G>C,NM_198696.2:c.132C>G,NP_941969.2:p.Thr44=,1/1,\N,Unknown significance,\N,synonymous_variant,0.01,0.000118147,EVS_EA_AF,TSPEAR
506464,21:45978468:G>C,NM_198696.2:c.131C>G,NP_941969.2:p.Thr44Ser,1/1,\N,Likely benign,\N,missense_variant,0.002,0.0038,1KG_AFR_AF,TSPEAR
506465,21:45978473:G>C,NM_198696.2:c.126C>G,NP_941969.2:p.Cys42Trp,1/1,\N,Unknown significance,\N,missense_variant,17.57,\N,\N,TSPEAR
506466,21:45978474:C>G,NM_198696.2:c.125G>C,NP_941969.2:p.Cys42Ser,1/1,\N,Likely benign,\N,missense_variant,3.332,0.0015,1KG_AFR_AF,TSPEAR
506467,21:45978475:AG>A,NM_198696.2:c.123del,NP_941969.2:p.Cys42AlafsTer2,1/1,\N,Unknown significance,\N,frameshift_variant,15.16,0.00091047,EXAC_FIN_AF,TSPEAR
506468,21:45978477:G>A,NM_198696.2:c.122C>T,NP_941969.2:p.Pro41Leu,1/1,\N,Unknown significance,\N,missense_variant,10.14,0.000121788,EXAC_SAS_AF,TSPEAR
506469,21:45978482:C>A,NM_198696.2:c.117G>T,NP_941969.2:p.Pro39=,1/1,\N,Unknown significance,\N,synonymous_variant,11.96,0.0000609162,EXAC_SAS_AF,TSPEAR
506470,21:45978482:C>G,NM_198696.2:c.117G>C,NP_941969.2:p.Pro39=,1/1,\N,Unknown significance,\N,synonymous_variant,7.545,0.0000870322,EXAC_AMR_AF,TSPEAR
506471,21:45978482:C>T,NM_198696.2:c.117G>A,NP_941969.2:p.Pro39=,1/1,\N,Unknown significance,\N,synonymous_variant,11.35,0.001,1KG_EAS_AF,TSPEAR
506472,21:45978483:G>A,NM_198696.2:c.116C>T,NP_941969.2:p.Pro39Leu,1/1,\N,Benign,\N,missense_variant,22.2,0.008,1KG_EUR_AF,TSPEAR
506473,21:45978485:GGC>G,NM_198696.2:c.112_113del,NP_941969.2:p.Ala38ProfsTer25,1/1,\N,Unknown significance,\N,frameshift_variant,24.9,0.000304544,EXAC_SAS_AF,TSPEAR
506474,21:45978486:G>A,NM_198696.2:c.113C>T,NP_941969.2:p.Ala38Val,1/1,\N,Likely benign,\N,missense_variant,11.79,0.00112108,EXAC_OTH_AF,TSPEAR
506475,21:45978487:C>T,NM_198696.2:c.112G>A,NP_941969.2:p.Ala38Thr,1/1,\N,Likely benign,\N,missense_variant,10.38,0.001,1KG_SAS_AF,TSPEAR
506476,21:45978488:G>A,NM_198696.2:c.111C>T,NP_941969.2:p.Cys37=,1/1,\N,Benign,\N,synonymous_variant,1.045,0.476437,EXAC_FIN_AF,TSPEAR
506477,21:45978488:GCAGCAGCTGGTGGCG>ACAGCAGCTGGGGGCA,NM_198696.2:c.96_111delinsTGCCCCCAGCTGCTGT,NP_941969.2:p.Thr34Pro,1/1,\N,Unknown significance,\N,missense_variant,\N,\N,\N,TSPEAR
506478,21:45978490:AGCAGCTGGTGGCG>A,NM_198696.2:c.96_108del,NP_941969.2:p.Thr34ProfsTer6,1/1,\N,Unknown significance,\N,frameshift_variant,26.2,\N,\N,TSPEAR
506479,21:45978496:TGGTGGCGCAGCAG>T,NM_198696.2:c.90_102del,NP_941969.2:p.Cys31AlafsTer9,1/1,\N,Unknown significance,\N,frameshift_variant,32,\N,\N,TSPEAR
506480,21:45978498:GT>G,NM_198696.2:c.100del,NP_941969.2:p.Thr34ProfsTer10,1/1,\N,Unknown significance,\N,frameshift_variant,20.9,0.000106,EXAC_AFR_AF,TSPEAR
506481,21:45978499:T>G,NM_198696.2:c.100A>C,NP_941969.2:p.Thr34Pro,1/1,\N,Benign,\N,missense_variant,0.003,0.9563,1KG_EUR_AF,TSPEAR
506482,21:45978502:C>T,NM_198696.2:c.97G>A,NP_941969.2:p.Ala33Thr,1/1,\N,Unknown significance,\N,missense_variant,2.371,0.000305923,EXAC_SAS_AF,TSPEAR
506483,21:45978503:G>A,NM_198696.2:c.96C>T,NP_941969.2:p.Cys32=,1/1,\N,Benign,\N,synonymous_variant,0.414,0.9563,1KG_EUR_AF,TSPEAR
506484,21:45978505:A>T,NM_198696.2:c.94T>A,NP_941969.2:p.Cys32Ser,1/1,\N,Unknown significance,\N,missense_variant,6.856,0.000694123,EVS_AA_AF,TSPEAR
506485,21:45978508:A>AG,NM_198696.2:c.90dup,NP_941969.2:p.Cys31LeufsTer33,1/1,\N,Unknown significance,\N,frameshift_variant,24.1,0.0000302471,EXAC_NFE_AF,TSPEAR
506486,21:45978508:AG>A,NM_198696.2:c.90del,NP_941969.2:p.Cys31AlafsTer13,1/1,\N,Benign,\N,frameshift_variant,24,0.0061,1KG_SAS_AF,TSPEAR
506487,21:45978508:A>G,NM_198696.2:c.91T>C,NP_941969.2:p.Cys31Arg,1/1,\N,Unknown significance,\N,missense_variant,19.45,0.0000907414,EXAC_NFE_AF,TSPEAR
506488,21:45978510:G>A,NM_198696.2:c.89C>T,NP_941969.2:p.Pro30Leu,1/1,\N,Unknown significance,\N,missense_variant,22,0.0000151295,EXAC_NFE_AF,TSPEAR
506489,21:45978510:G>T,NM_198696.2:c.89C>A,NP_941969.2:p.Pro30His,1/1,\N,Unknown significance,\N,missense_variant,18.63,0.001,1KG_EAS_AF,TSPEAR
506490,21:45978511:G>A,NM_198696.2:c.88C>T,NP_941969.2:p.Pro30Ser,1/1,\N,Unknown significance,\N,missense_variant,10.9,0.0000610054,EXAC_SAS_AF,TSPEAR
506491,21:45978512:G>A,NM_198696.2:c.87C>T,NP_941969.2:p.Pro29=,1/1,\N,Unknown significance,\N,synonymous_variant,8.52,\N,\N,TSPEAR
506492,21:45978513:G>A,NM_198696.2:c.86C>T,NP_941969.2:p.Pro29Leu,1/1,\N,Unknown significance,\N,missense_variant,23.7,0.000229885,EVS_AA_AF,TSPEAR
506493,21:45978514:G>C,NM_198696.2:c.85C>G,NP_941969.2:p.Pro29Ala,1/1,\N,Unknown significance,\N,missense_variant,19.57,0.0000150802,EXAC_NFE_AF,TSPEAR
506494,21:45978514:G>T,NM_198696.2:c.85C>A,NP_941969.2:p.Pro29Thr,1/1,\N,Benign,\N,missense_variant,22.2,0.0061,1KG_SAS_AF,TSPEAR
506495,21:45978515:C>G,NM_198696.2:c.84G>C,NP_941969.2:p.Glu28Asp,1/1,\N,Unknown significance,\N,missense_variant,23.4,0.0000150766,EXAC_NFE_AF,TSPEAR
506496,21:45978518:A>G,NM_198696.2:c.81T>C,NP_941969.2:p.Cys27=,1/1,\N,Benign,\N,synonymous_variant,0.381,0.0711,1KG_AFR_AF,TSPEAR
506497,21:45978520:A>G,NM_198696.2:c.79T>C,NP_941969.2:p.Cys27Arg,1/1,\N,Unknown significance,\N,missense_variant,22.8,0.0000611023,EXAC_SAS_AF,TSPEAR
506498,21:45978528:T>C,NM_198696.2:c.71A>G,NP_941969.2:p.Glu24Gly,1/1,\N,Unknown significance,\N,missense_variant,23.5,0.0000301368,EXAC_NFE_AF,TSPEAR
506499,21:45978530:T>C,NM_198696.2:c.69A>G,NP_941969.2:p.Pro23=,1/1,\N,Unknown significance,\N,synonymous_variant,5.195,0.0000613497,EXAC_SAS_AF,TSPEAR
506500,21:45978533:G>A,NM_198696.2:c.66C>T,NP_941969.2:p.Cys22=,1/1,\N,Unknown significance,\N,synonymous_variant,6.871,0.0000150657,EXAC_NFE_AF,TSPEAR
506501,21:45978537:G>T,NM_198696.2:c.62C>A,NP_941969.2:p.Ala21Asp,1/1,\N,Benign,\N,missense_variant,8.351,0.0166,1KG_AFR_AF,TSPEAR
506502,21:45978538:C>T,NM_198696.2:c.61G>A,NP_941969.2:p.Ala21Thr,1/1,\N,Benign,\N,missense_variant,25.1,0.0333,1KG_AFR_AF,TSPEAR
506503,21:45978539:G>A,NM_198696.2:c.60C>T,NP_941969.2:p.Asp20=,1/1,\N,Benign,\N,synonymous_variant,9.657,0.0219,1KG_AFR_AF,TSPEAR
506504,21:45978544:C>A,NM_198696.2:c.55G>T,NP_941969.2:p.Val19Leu,1/1,\N,Unknown significance,\N,missense_variant,20.2,0.0000618353,EXAC_SAS_AF,TSPEAR
506505,21:45978547:G>T,NM_198696.2:c.52C>A,NP_941969.2:p.Gln18Lys,1/1,\N,Unknown significance,\N,missense_variant,22.6,0.0000150557,EXAC_NFE_AF,TSPEAR
506506,21:45978550:A>G,NM_198696.2:c.49T>C,NP_941969.2:p.Trp17Arg,1/1,\N,Unknown significance,\N,missense_variant,22.7,\N,\N,TSPEAR
506507,21:45978553:A>C,NM_198696.2:c.46T>G,NP_941969.2:p.Ser16Ala,1/1,\N,Unknown significance,\N,missense_variant,14.15,0.000314228,EXAC_SAS_AF,TSPEAR
506508,21:45978557:A>G,NM_198696.2:c.42T>C,NP_941969.2:p.Ser14=,1/1,\N,Benign,\N,synonymous_variant,0.013,0.0366788,EXAC_AFR_AF,TSPEAR
506509,21:45978561:T>C,NM_198696.2:c.38A>G,NP_941969.2:p.Tyr13Cys,1/1,\N,Unknown significance,\N,missense_variant,0.006,0.00311683,EXAC_AFR_AF,TSPEAR
506510,21:45978565:C>A,NM_198696.2:c.34G>T,NP_941969.2:p.Ala12Ser,1/1,\N,Unknown significance,\N,missense_variant,0.005,0.0000645661,EXAC_SAS_AF,TSPEAR
506511,21:45978565:C>T,NM_198696.2:c.34G>A,NP_941969.2:p.Ala12Thr,1/1,\N,Unknown significance,\N,missense_variant,0.004,0.000100402,EXAC_AFR_AF,TSPEAR
506512,21:45978566:G>A,NM_198696.2:c.33C>T,NP_941969.2:p.Ser11=,1/1,\N,Benign,\N,synonymous_variant,5.905,0.0069,1KG_EAS_AF,TSPEAR
506513,21:45978566:G>T,NM_198696.2:c.33C>A,NP_941969.2:p.Ser11Arg,1/1,\N,Unknown significance,\N,missense_variant,15.9,0.0000864902,EXAC_AMR_AF,TSPEAR
506514,21:45978571:A>G,NM_198696.2:c.28T>C,NP_941969.2:p.Ser10Pro,1/1,\N,Unknown significance,\N,missense_variant,22.4,0.0014,1KG_AMR_AF,TSPEAR
506515,21:45978574:A>G,NM_198696.2:c.25T>C,NP_941969.2:p.Cys9Arg,1/1,\N,Unknown significance,\N,missense_variant,15.26,\N,\N,TSPEAR
506516,21:45978577:C>T,NM_198696.2:c.22G>A,NP_941969.2:p.Val8Ile,1/1,\N,Unknown significance,\N,missense_variant,6.542,\N,\N,TSPEAR
506517,21:45978578:G>A,NM_198696.2:c.21C>T,NP_941969.2:p.Ser7=,1/1,\N,Benign,\N,synonymous_variant,10.33,0.0099,1KG_EAS_AF,TSPEAR
506518,21:45978580:A>G,NM_198696.2:c.19T>C,NP_941969.2:p.Ser7Pro,1/1,\N,Unknown significance,\N,missense_variant,18.64,0.001,1KG_EUR_AF,TSPEAR
506519,21:45978587:A>AGACAT,NM_198696.2:c.11_12insATGTC,NP_941969.2:p.Thr5CysfsTer41,1/1,\N,Unknown significance,\N,frameshift_variant,\N,\N,\N,TSPEAR
506520,21:45978587:A>G,NM_198696.2:c.12T>C,NP_941969.2:p.Ser4=,1/1,\N,Benign,\N,synonymous_variant,0.017,0.345501,EXAC_FIN_AF,TSPEAR
506521,21:45978587:A>GGACGC,NM_198696.2:c.12delinsGCGTCC,NP_941969.2:p.Thr5ArgfsTer41,1/1,\N,Unknown significance,\N,frameshift_variant,\N,\N,\N,TSPEAR
506522,21:45978587:A>T,NM_198696.2:c.12T>A,NP_941969.2:p.Ser4=,1/1,\N,Unknown significance,\N,synonymous_variant,0.002,0.0000152235,EXAC_NFE_AF,TSPEAR
506523,21:45978590:C>T,NM_198696.2:c.9G>A,NP_941969.2:p.Thr3=,1/1,\N,Unknown significance,\N,synonymous_variant,9.782,0.0015,1KG_AFR_AF,TSPEAR
506524,21:45978591:G>A,NM_198696.2:c.8C>T,NP_941969.2:p.Thr3Met,1/1,\N,Benign,\N,missense_variant,11.76,0.186977,EVS_EA_AF,TSPEAR
506525,21:45978592:T>C,NM_198696.2:c.7A>G,NP_941969.2:p.Thr3Ala,1/1,\N,Benign,\N,missense_variant,0.001,0.34641,EXAC_FIN_AF,TSPEAR
506526,21:45978593:G>A,NM_198696.2:c.6C>T,NP_941969.2:p.Ala2=,1/1,\N,Unknown significance,\N,synonymous_variant,6.881,0.0000308814,EXAC_NFE_AF,TSPEAR
506527,21:45978594:G>A,NM_198696.2:c.5C>T,NP_941969.2:p.Ala2Val,1/1,\N,Unknown significance,\N,missense_variant,22.8,0.00009994,EXAC_AFR_AF,TSPEAR
506528,21:45978599:G>A,NM_198696.2:c.-1C>T,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,12.29,0.000349325,EXAC_EAS_AF,TSPEAR
506529,21:45978600:CTGGGGTGGGGAGGAGGTGAGCTGGGGGAGACGTGAGT>C,NM_198696.2:c.-39_-3del,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,\N,\N,\N,TSPEAR
506530,21:45978601:TG>T,NM_198696.2:c.-4del,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,9.056,\N,\N,TSPEAR
506531,21:45978604:G>A,NM_198696.2:c.-6C>T,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,8.581,0.000226963,EVS_AA_AF,TSPEAR
506532,21:45978607:G>A,NM_198696.2:c.-9C>T,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,4.905,0.000015527,EXAC_NFE_AF,TSPEAR
506533,21:45978614:A>T,NM_198696.2:c.-16T>A,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,8.592,0.000116279,EVS_EA_AF,TSPEAR
506534,21:45978615:G>A,NM_198696.2:c.-17C>T,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,12.19,\N,\N,TSPEAR
506535,21:45978618:G>A,NM_198696.2:c.-20C>T,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,12.85,\N,\N,TSPEAR
506536,21:45978618:G>C,NM_198696.2:c.-20C>G,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,11.05,0.0000870322,EXAC_AMR_AF,TSPEAR
506537,21:45978622:T>G,NM_198696.2:c.-24A>C,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,13.88,\N,\N,TSPEAR
506538,21:45978624:G>T,NM_198696.2:c.-26C>A,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,12.19,0.000140318,EXAC_NFE_AF,TSPEAR
506539,21:45978631:C>CGTGA,NM_198696.2:c.-37_-34dup,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,10.37,0.000301932,EXAC_AFR_AF,TSPEAR
506540,21:45978631:C>G,NM_198696.2:c.-33G>C,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,2.334,0.00411985,EXAC_NFE_AF,TSPEAR
506541,21:45978631:C>T,NM_198696.2:c.-33G>A,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,5.222,0.00201288,EXAC_AFR_AF,TSPEAR
506542,21:45978632:G>A,NM_198696.2:c.-34C>T,\N,1/1,\N,Benign,\N,5_prime_UTR_variant,8.609,0.00771675,EVS_AA_AF,TSPEAR
506543,21:45978633:TGAGTGAGTGAGTGTGG>T,NM_144991.2:c.303+9020_303+9035del,\N,\N,2/11,Unknown significance,\N,intron_variant,4.572,\N,\N,TSPEAR
506544,21:45978636:G>C,NM_198696.2:c.-38C>G,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,1.478,0.000151286,EXAC_FIN_AF,TSPEAR
506545,21:45978637:TGAGTGAGTGTGG>T,NM_144991.2:c.303+9020_303+9031del,\N,\N,2/11,Unknown significance,\N,intron_variant,4.225,\N,\N,TSPEAR
506546,21:45978638:G>A,NM_198696.2:c.-40C>T,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,2.435,0.0000870928,EXAC_AMR_AF,TSPEAR
506547,21:45978640:G>A,NM_198696.2:c.-42C>T,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,5.341,0.000352361,EXAC_EAS_AF,TSPEAR
506548,21:45978642:G>C,NM_198696.2:c.-44C>G,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,1.921,0.0000156216,EXAC_NFE_AF,TSPEAR
506549,21:45978644:G>A,NM_144991.2:c.303+9025C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.3,0.000087108,EXAC_AMR_AF,TSPEAR
506550,21:45978649:GGAGT>G,NM_144991.2:c.303+9016_303+9019del,\N,\N,2/11,Unknown significance,\N,intron_variant,10.25,0.000109099,EXAC_SAS_AF,TSPEAR
506551,21:45978650:G>A,NM_144991.2:c.303+9019C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,5.805,0.0000871536,EXAC_AMR_AF,TSPEAR
506552,21:45978669:T>G,NM_144991.2:c.303+9000A>C,\N,\N,2/11,Unknown significance,\N,intron_variant,8.291,0.0008,1KG_AFR_AF,TSPEAR
506553,21:45978677:C>T,NM_144991.2:c.303+8992G>A,\N,\N,2/11,Benign,\N,intron_variant,3.698,0.0491,1KG_SAS_AF,TSPEAR
506554,21:45978682:C>G,NM_144991.2:c.303+8987G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.808,0.001,1KG_SAS_AF,TSPEAR
506555,21:45978699:G>A,NM_144991.2:c.303+8970C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.092,0.001,1KG_SAS_AF,TSPEAR
506556,21:45978704:C>T,NM_144991.2:c.303+8965G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.207,\N,\N,TSPEAR
506557,21:45978708:A>G,NM_144991.2:c.303+8961T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,10.47,0.0031,1KG_SAS_AF,TSPEAR
506558,21:45978748:G>A,NM_144991.2:c.303+8921C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.421,\N,\N,TSPEAR
506559,21:45978765:CTTG>C,NM_144991.2:c.303+8901_303+8903del,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
506560,21:45978770:T>G,NM_144991.2:c.303+8899A>C,\N,\N,2/11,Unknown significance,\N,intron_variant,6.851,0.002,1KG_SAS_AF,TSPEAR
506561,21:45978799:T>C,NM_144991.2:c.303+8870A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.793,0.001,1KG_EAS_AF,TSPEAR
506562,21:45978807:C>A,NM_144991.2:c.303+8862G>T,\N,\N,2/11,Benign,\N,intron_variant,4.316,0.0545,1KG_AFR_AF,TSPEAR
506563,21:45978882:A>G,NM_144991.2:c.303+8787T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.025,0.002,1KG_SAS_AF,TSPEAR
506564,21:45978898:A>G,NM_144991.2:c.303+8771T>C,\N,\N,2/11,Benign,\N,intron_variant,2.84,0.2575,1KG_EUR_AF,TSPEAR
506565,21:45978923:T>A,NM_144991.2:c.303+8746A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,5.178,\N,\N,TSPEAR
506566,21:45978938:A>G,NM_144991.2:c.303+8731T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.533,\N,\N,TSPEAR
506567,21:45978945:G>T,NM_144991.2:c.303+8724C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.019,\N,\N,TSPEAR
506568,21:45979002:T>C,NM_144991.2:c.303+8667A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.828,0.001,1KG_EUR_AF,TSPEAR
506569,21:45979003:T>TA,NM_144991.2:c.303+8665dup,\N,\N,2/11,Benign,\N,intron_variant,1.46,0.0113,1KG_AFR_AF,TSPEAR
506570,21:45979024:A>G,NM_144991.2:c.303+8645T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.785,0.001,1KG_EUR_AF,TSPEAR
506571,21:45979032:A>T,NM_144991.2:c.303+8637T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.913,\N,\N,TSPEAR
506572,21:45979037:G>A,NM_144991.2:c.303+8632C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.288,\N,\N,TSPEAR
506573,21:45979080:T>C,NM_144991.2:c.303+8589A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.219,\N,\N,TSPEAR
506574,21:45979091:G>A,NM_144991.2:c.303+8578C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.619,0.001,1KG_EAS_AF,TSPEAR
506575,21:45979105:A>G,NM_144991.2:c.303+8564T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.161,0.001,1KG_EAS_AF,TSPEAR
506576,21:45979110:C>T,NM_144991.2:c.303+8559G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.079,0.001,1KG_EAS_AF,TSPEAR
506577,21:45979129:C>T,NM_144991.2:c.303+8540G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.218,\N,\N,TSPEAR
506578,21:45979130:G>A,NM_144991.2:c.303+8539C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.776,0.002,1KG_SAS_AF,TSPEAR
506579,21:45979132:C>T,NM_144991.2:c.303+8537G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.313,0.002,1KG_SAS_AF,TSPEAR
506580,21:45979133:G>A,NM_144991.2:c.303+8536C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.024,0.0014,1KG_AMR_AF,TSPEAR
506581,21:45979140:A>AC,NM_144991.2:c.303+8528dup,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
506582,21:45979162:G>C,NM_144991.2:c.303+8507C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.304,0.001,1KG_SAS_AF,TSPEAR
506583,21:45979188:T>C,NM_144991.2:c.303+8481A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.731,\N,\N,TSPEAR
506584,21:45979228:A>G,NM_144991.2:c.303+8441T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.301,0.001,1KG_EUR_AF,TSPEAR
506585,21:45979246:G>A,NM_144991.2:c.303+8423C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,5.778,0.001,1KG_SAS_AF,TSPEAR
506586,21:45979249:T>C,NM_144991.2:c.303+8420A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.107,\N,\N,TSPEAR
506587,21:45979253:T>C,NM_144991.2:c.303+8416A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,2.691,\N,\N,TSPEAR
506588,21:45979255:G>A,NM_144991.2:c.303+8414C>T,\N,\N,2/11,Benign,\N,intron_variant,2.111,0.9553,1KG_EUR_AF,TSPEAR
506589,21:45979260:G>A,NM_144991.2:c.303+8409C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,3.536,\N,\N,TSPEAR
506590,21:45979274:C>A,NM_144991.2:c.303+8395G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,7.486,\N,\N,TSPEAR
506591,21:45979292:A>G,NM_144991.2:c.303+8377T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.425,0.001,1KG_SAS_AF,TSPEAR
506592,21:45979333:C>T,NM_144991.2:c.303+8336G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.064,0.0008,1KG_AFR_AF,TSPEAR
506593,21:45979336:G>A,NM_144991.2:c.303+8333C>T,\N,\N,2/11,Benign,\N,intron_variant,2.496,0.0173,1KG_AMR_AF,TSPEAR
506594,21:45979348:T>C,NM_144991.2:c.303+8321A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.072,\N,\N,TSPEAR
506595,21:45979361:C>T,NM_144991.2:c.303+8308G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.844,0.001,1KG_SAS_AF,TSPEAR
506596,21:45979362:G>A,NM_144991.2:c.303+8307C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.584,\N,\N,TSPEAR
506597,21:45979379:T>C,NM_144991.2:c.303+8290A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.218,\N,\N,TSPEAR
506598,21:45979406:G>A,NM_144991.2:c.303+8263C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.072,0.001,1KG_SAS_AF,TSPEAR
506599,21:45979417:C>T,NM_144991.2:c.303+8252G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.747,0.001,1KG_EUR_AF,TSPEAR
506600,21:45979421:C>T,NM_144991.2:c.303+8248G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.749,0.0008,1KG_AFR_AF,TSPEAR
506601,21:45979423:A>G,NM_144991.2:c.303+8246T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.953,\N,\N,TSPEAR
506602,21:45979427:T>C,NM_144991.2:c.303+8242A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.141,0.001,1KG_EUR_AF,TSPEAR
506603,21:45979434:G>T,NM_144991.2:c.303+8235C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.557,\N,\N,TSPEAR
506604,21:45979446:G>C,NM_144991.2:c.303+8223C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.872,\N,\N,TSPEAR
506605,21:45979509:A>G,NM_144991.2:c.303+8160T>C,\N,\N,2/11,Benign,\N,intron_variant,1.656,0.0159,1KG_EAS_AF,TSPEAR
506606,21:45979523:T>C,NM_144991.2:c.303+8146A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.135,0.0008,1KG_AFR_AF,TSPEAR
506607,21:45979524:G>T,NM_144991.2:c.303+8145C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.24,\N,\N,TSPEAR
506608,21:45979542:G>C,NM_144991.2:c.303+8127C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.105,\N,\N,TSPEAR
506609,21:45979557:T>A,NM_144991.2:c.303+8112A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,7.282,\N,\N,TSPEAR
506610,21:45979604:C>T,NM_144991.2:c.303+8065G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.616,0.0041,1KG_SAS_AF,TSPEAR
506611,21:45979605:G>A,NM_144991.2:c.303+8064C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.633,0.0008,1KG_AFR_AF,TSPEAR
506612,21:45979610:C>T,NM_144991.2:c.303+8059G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.216,0.002,1KG_EAS_AF,TSPEAR
506613,21:45979616:T>C,NM_144991.2:c.303+8053A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.965,\N,\N,TSPEAR
506614,21:45979620:C>T,NM_144991.2:c.303+8049G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.219,0.0008,1KG_AFR_AF,TSPEAR
506615,21:45979713:G>C,NM_144991.2:c.303+7956C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.187,0.004,1KG_EAS_AF,TSPEAR
506616,21:45979714:A>G,NM_144991.2:c.303+7955T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.625,\N,\N,TSPEAR
506617,21:45979761:G>A,NM_144991.2:c.303+7908C>T,\N,\N,2/11,Benign,\N,intron_variant,3.006,0.5239,1KG_EUR_AF,TSPEAR
506618,21:45979762:G>A,NM_144991.2:c.303+7907C>T,\N,\N,2/11,Benign,\N,intron_variant,3.222,0.0129,1KG_AFR_AF,TSPEAR
506619,21:45979821:T>G,NM_144991.2:c.303+7848A>C,\N,\N,2/11,Unknown significance,\N,intron_variant,4.598,0.0014,1KG_AMR_AF,TSPEAR
506620,21:45979830:T>C,NM_144991.2:c.303+7839A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.93,0.001,1KG_SAS_AF,TSPEAR
506621,21:45979851:G>A,NM_144991.2:c.303+7818C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,5.312,0.0008,1KG_AFR_AF,TSPEAR
506622,21:45979854:T>TAC,NM_144991.2:c.303+7813_303+7814dup,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
506623,21:45979861:C>A,NM_144991.2:c.303+7808G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,5.453,0.0043,1KG_AMR_AF,TSPEAR
506624,21:45979933:A>G,NM_144991.2:c.303+7736T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.376,0.001,1KG_SAS_AF,TSPEAR
506625,21:45979944:C>A,NM_144991.2:c.303+7725G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.985,0.001,1KG_SAS_AF,TSPEAR
506626,21:45979946:C>T,NM_144991.2:c.303+7723G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.039,0.0014,1KG_AMR_AF,TSPEAR
506627,21:45979947:G>T,NM_144991.2:c.303+7722C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.019,0.001,1KG_EAS_AF,TSPEAR
506628,21:45979994:A>G,NM_144991.2:c.303+7675T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.219,\N,\N,TSPEAR
506629,21:45980006:T>C,NM_144991.2:c.303+7663A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.746,0.001,1KG_EAS_AF,TSPEAR
506630,21:45980047:C>T,NM_144991.2:c.303+7622G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.311,0.001,1KG_EUR_AF,TSPEAR
506631,21:45980048:G>A,NM_144991.2:c.303+7621C>T,\N,\N,2/11,Benign,\N,intron_variant,1.499,0.3909,1KG_EAS_AF,TSPEAR
506632,21:45980064:AT>A,NM_144991.2:c.303+7604del,\N,\N,2/11,Benign,\N,intron_variant,10.22,0.0166,1KG_AFR_AF,TSPEAR
506633,21:45980067:C>T,NM_144991.2:c.303+7602G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,12.46,\N,\N,TSPEAR
506634,21:45980123:G>T,NM_144991.2:c.303+7546C>A,\N,\N,2/11,Benign,\N,intron_variant,0.644,0.1471,1KG_EUR_AF,TSPEAR
506635,21:45980134:T>C,NM_144991.2:c.303+7535A>G,\N,\N,2/11,Benign,\N,intron_variant,1.053,0.0537,1KG_AFR_AF,TSPEAR
506636,21:45980138:A>G,NM_144991.2:c.303+7531T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.049,0.0008,1KG_AFR_AF,TSPEAR
506637,21:45980153:A>G,NM_144991.2:c.303+7516T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.378,\N,\N,TSPEAR
506638,21:45980179:T>C,NM_144991.2:c.303+7490A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.863,0.0015,1KG_AFR_AF,TSPEAR
506639,21:45980186:A>G,NM_144991.2:c.303+7483T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.572,\N,\N,TSPEAR
506640,21:45980194:T>TA,NM_144991.2:c.303+7474dup,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
506641,21:45980211:A>G,NM_144991.2:c.303+7458T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.628,\N,\N,TSPEAR
506642,21:45980298:G>C,NM_144991.2:c.303+7371C>G,\N,\N,2/11,Benign,\N,intron_variant,0.3,0.1543,1KG_AFR_AF,TSPEAR
506643,21:45980300:C>T,NM_144991.2:c.303+7369G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.527,0.0008,1KG_AFR_AF,TSPEAR
506644,21:45980307:A>G,NM_144991.2:c.303+7362T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.334,\N,\N,TSPEAR
506645,21:45980309:G>A,NM_144991.2:c.303+7360C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.683,\N,\N,TSPEAR
506646,21:45980363:G>A,NM_144991.2:c.303+7306C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.526,0.002,1KG_SAS_AF,TSPEAR
506647,21:45980385:A>G,NM_144991.2:c.303+7284T>C,\N,\N,2/11,Benign,\N,intron_variant,8.717,0.0368,1KG_EUR_AF,TSPEAR
506648,21:45980401:C>T,NM_144991.2:c.303+7268G>A,\N,\N,2/11,Benign,\N,intron_variant,11.17,0.0356,1KG_AFR_AF,TSPEAR
506649,21:45980402:A>T,NM_144991.2:c.303+7267T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,9.955,0.0008,1KG_AFR_AF,TSPEAR
506650,21:45980414:A>T,NM_144991.2:c.303+7255T>A,\N,\N,2/11,Benign,\N,intron_variant,0.702,0.0368,1KG_EUR_AF,TSPEAR
506651,21:45980435:C>T,NM_144991.2:c.303+7234G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,6.439,\N,\N,TSPEAR
506652,21:45980441:T>G,NM_144991.2:c.303+7228A>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.255,\N,\N,TSPEAR
506653,21:45980446:A>G,NM_144991.2:c.303+7223T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.384,0.002,1KG_EAS_AF,TSPEAR
506654,21:45980477:C>T,NM_144991.2:c.303+7192G>A,\N,\N,2/11,Benign,\N,intron_variant,7.272,0.9553,1KG_EUR_AF,TSPEAR
506655,21:45980484:A>G,NM_144991.2:c.303+7185T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,4.692,\N,\N,TSPEAR
506656,21:45980508:A>G,NM_144991.2:c.303+7161T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,4.587,0.001,1KG_EAS_AF,TSPEAR
506657,21:45980518:C>T,NM_144991.2:c.303+7151G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.109,0.001,1KG_SAS_AF,TSPEAR
506658,21:45980520:G>A,NM_144991.2:c.303+7149C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.536,0.0008,1KG_AFR_AF,TSPEAR
506659,21:45980560:C>G,NM_144991.2:c.303+7109G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,11.77,0.001,1KG_EUR_AF,TSPEAR
506660,21:45980585:G>A,NM_144991.2:c.303+7084C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,13.14,\N,\N,TSPEAR
506661,21:45980590:T>C,NM_144991.2:c.303+7079A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,15.25,\N,\N,TSPEAR
506662,21:45980598:C>T,NM_144991.2:c.303+7071G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,16.47,0.002,1KG_EUR_AF,TSPEAR
506663,21:45980603:TC>T,NM_144991.2:c.303+7065del,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
506664,21:45980629:G>A,NM_144991.2:c.303+7040C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.027,0.001,1KG_SAS_AF,TSPEAR
506665,21:45980637:G>A,NM_144991.2:c.303+7032C>T,\N,\N,2/11,Benign,\N,intron_variant,6.838,0.0159,1KG_EAS_AF,TSPEAR
506666,21:45980672:A>G,NM_144991.2:c.303+6997T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.388,\N,\N,TSPEAR
506667,21:45980700:G>C,NM_144991.2:c.303+6969C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.153,0.001,1KG_EAS_AF,TSPEAR
506668,21:45980707:G>A,NM_144991.2:c.303+6962C>T,\N,\N,2/11,Benign,\N,intron_variant,1.347,0.0416,1KG_AFR_AF,TSPEAR
506669,21:45980723:C>A,NM_144991.2:c.303+6946G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.047,0.001,1KG_EAS_AF,TSPEAR
506670,21:45980767:A>G,NM_144991.2:c.303+6902T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,9.057,0.001,1KG_EAS_AF,TSPEAR
506671,21:45980831:C>T,NM_144991.2:c.303+6838G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,8.75,\N,\N,TSPEAR
506672,21:45980839:A>G,NM_144991.2:c.303+6830T>C,\N,\N,2/11,Benign,\N,intron_variant,6.453,0.0719,1KG_AFR_AF,TSPEAR
506673,21:45980848:C>T,NM_144991.2:c.303+6821G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.5,0.001,1KG_EAS_AF,TSPEAR
506674,21:45980871:G>A,NM_144991.2:c.303+6798C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.064,0.001,1KG_EAS_AF,TSPEAR
506675,21:45980905:CA>C,NM_144991.2:c.303+6763del,\N,\N,2/11,Benign,\N,intron_variant,3.837,0.0151,1KG_AFR_AF,TSPEAR
506676,21:45980913:T>C,NM_144991.2:c.303+6756A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.4,\N,\N,TSPEAR
506677,21:45980926:G>A,NM_144991.2:c.303+6743C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,4.392,\N,\N,TSPEAR
506678,21:45980949:A>G,NM_144991.2:c.303+6720T>C,\N,\N,2/11,Benign,\N,intron_variant,5.703,0.0058,1KG_AMR_AF,TSPEAR
506679,21:45980983:G>A,NM_144991.2:c.303+6686C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,13.72,0,1KG_ALL_AF|1KG_AFR_AF|1KG_AMR_AF|1KG_EAS_AF|1KG_EUR_AF|1KG_SAS_AF,TSPEAR
506680,21:45980986:G>A,NM_144991.2:c.303+6683C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,14.02,0,1KG_ALL_AF|1KG_AFR_AF|1KG_AMR_AF|1KG_EAS_AF|1KG_EUR_AF|1KG_SAS_AF,TSPEAR
506681,21:45981006:T>A,NM_144991.2:c.303+6663A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,20.5,0,1KG_ALL_AF|1KG_AFR_AF|1KG_AMR_AF|1KG_EAS_AF|1KG_EUR_AF|1KG_SAS_AF,TSPEAR
506682,21:45981015:T>A,NM_144991.2:c.303+6654A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,19.69,0,1KG_ALL_AF|1KG_AFR_AF|1KG_AMR_AF|1KG_EAS_AF|1KG_EUR_AF|1KG_SAS_AF,TSPEAR
506683,21:45981021:A>G,NM_144991.2:c.303+6648T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,17.02,0.001,1KG_EAS_AF,TSPEAR
506684,21:45981081:A>G,NM_144991.2:c.303+6588T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.98,0.001,1KG_EUR_AF,TSPEAR
506685,21:45981137:A>T,NM_144991.2:c.303+6532T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,7.944,\N,\N,TSPEAR
506686,21:45981144:C>A,NM_144991.2:c.303+6525G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,6.921,0.001,1KG_EUR_AF,TSPEAR
506687,21:45981165:GGAA>G,NM_144991.2:c.303+6501_303+6503del,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
506688,21:45981188:G>A,NM_144991.2:c.303+6481C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.061,0.002,1KG_EAS_AF,TSPEAR
506689,21:45981207:A>G,NM_144991.2:c.303+6462T>C,\N,\N,2/11,Benign,\N,intron_variant,6.09,0.0227,1KG_AFR_AF,TSPEAR
506690,21:45981209:T>C,NM_144991.2:c.303+6460A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,6.7,\N,\N,TSPEAR
506691,21:45981223:A>G,NM_144991.2:c.303+6446T>C,\N,\N,2/11,Benign,\N,intron_variant,7.142,0.0069,1KG_EAS_AF,TSPEAR
506692,21:45981247:C>T,NM_144991.2:c.303+6422G>A,\N,\N,2/11,Benign,\N,intron_variant,3.61,0.0318,1KG_AFR_AF,TSPEAR
506693,21:45981253:C>T,NM_144991.2:c.303+6416G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,8.11,0.0014,1KG_AMR_AF,TSPEAR
506694,21:45981297:G>C,NM_144991.2:c.303+6372C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.104,\N,\N,TSPEAR
506695,21:45981308:C>T,NM_144991.2:c.303+6361G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,8.445,\N,\N,TSPEAR
506696,21:45981327:A>C,NM_144991.2:c.303+6342T>G,\N,\N,2/11,Benign,\N,intron_variant,10.53,0.0333,1KG_AFR_AF,TSPEAR
506697,21:45981339:G>A,NM_144991.2:c.303+6330C>T,\N,\N,2/11,Benign,\N,intron_variant,1.908,0.0537,1KG_AFR_AF,TSPEAR
506698,21:45981358:G>C,NM_144991.2:c.303+6311C>G,\N,\N,2/11,Benign,\N,intron_variant,1.19,0.9553,1KG_EUR_AF,TSPEAR
506699,21:45981381:C>T,NM_144991.2:c.303+6288G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,6.811,\N,\N,TSPEAR
506700,21:45981393:C>T,NM_144991.2:c.303+6276G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,9.811,0.0014,1KG_AMR_AF,TSPEAR
506701,21:45981395:T>G,NM_144991.2:c.303+6274A>C,\N,\N,2/11,Unknown significance,\N,intron_variant,9.88,\N,\N,TSPEAR
506702,21:45981415:G>T,NM_144991.2:c.303+6254C>A,\N,\N,2/11,Benign,\N,intron_variant,9.282,0.0113,1KG_AFR_AF,TSPEAR
506703,21:45981440:T>A,NM_144991.2:c.303+6229A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,6.1,0.0038,1KG_AFR_AF,TSPEAR
506704,21:45981458:T>C,NM_144991.2:c.303+6211A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,4.424,0.0023,1KG_AFR_AF,TSPEAR
506705,21:45981464:A>G,NM_144991.2:c.303+6205T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,6.152,\N,\N,TSPEAR
506706,21:45981499:G>A,NM_144991.2:c.303+6170C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,8.186,\N,\N,TSPEAR
506707,21:45981523:G>A,NM_144991.2:c.303+6146C>T,\N,\N,2/11,Benign,\N,intron_variant,16.53,0.0106,1KG_AFR_AF,TSPEAR
506708,21:45981523:G>C,NM_144991.2:c.303+6146C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,13.92,\N,\N,TSPEAR
506709,21:45981562:G>C,NM_144991.2:c.303+6107C>G,\N,\N,2/11,Benign,\N,intron_variant,0.049,0.1311,1KG_AMR_AF,TSPEAR
506710,21:45981569:C>T,NM_144991.2:c.303+6100G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.041,0.0008,1KG_AFR_AF,TSPEAR
506711,21:45981577:G>T,NM_144991.2:c.303+6092C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.08,\N,\N,TSPEAR
506712,21:45981594:G>C,NM_144991.2:c.303+6075C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.005,0.001,1KG_EAS_AF,TSPEAR
506713,21:45981649:A>G,NM_144991.2:c.303+6020T>C,\N,\N,2/11,Benign,\N,intron_variant,5.292,0.0076,1KG_AFR_AF,TSPEAR
506714,21:45981665:C>T,NM_144991.2:c.303+6004G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,9.706,0.0014,1KG_AMR_AF,TSPEAR
506715,21:45981671:T>A,NM_144991.2:c.303+5998A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,11.06,0.001,1KG_EAS_AF,TSPEAR
506716,21:45981684:G>C,NM_144991.2:c.303+5985C>G,\N,\N,2/11,Benign,\N,intron_variant,4.01,0.9553,1KG_EUR_AF,TSPEAR
506717,21:45981702:T>G,NM_144991.2:c.303+5967A>C,\N,\N,2/11,Unknown significance,\N,intron_variant,3.741,\N,\N,TSPEAR
506718,21:45981711:T>C,NM_144991.2:c.303+5958A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,2.807,\N,\N,TSPEAR
506719,21:45981727:G>A,NM_144991.2:c.303+5942C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,5.644,\N,\N,TSPEAR
506720,21:45981747:A>G,NM_144991.2:c.303+5922T>C,\N,\N,2/11,Benign,\N,intron_variant,1.806,0.006,1KG_EUR_AF,TSPEAR
506721,21:45981786:C>T,NM_144991.2:c.303+5883G>A,\N,\N,2/11,Benign,\N,intron_variant,4.157,0.9553,1KG_EUR_AF,TSPEAR
506722,21:45981797:C>G,NM_144991.2:c.303+5872G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.822,\N,\N,TSPEAR
506723,21:45981838:A>G,NM_144991.2:c.303+5831T>C,\N,\N,2/11,Benign,\N,intron_variant,9.649,0.0159,1KG_EAS_AF,TSPEAR
506724,21:45981865:G>A,NM_144991.2:c.303+5804C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.276,0.0008,1KG_AFR_AF,TSPEAR
506725,21:45981867:A>C,NM_144991.2:c.303+5802T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.447,\N,\N,TSPEAR
506726,21:45981898:C>T,NM_144991.2:c.303+5771G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.434,0.0014,1KG_AMR_AF,TSPEAR
506727,21:45981899:G>A,NM_144991.2:c.303+5770C>T,\N,\N,2/11,Benign,\N,intron_variant,0.189,0.0109,1KG_EAS_AF,TSPEAR
506728,21:45981908:A>C,NM_144991.2:c.303+5761T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.021,0.001,1KG_EUR_AF,TSPEAR
506729,21:45981976:G>T,NM_144991.2:c.303+5693C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.898,\N,\N,TSPEAR
506730,21:45981977:C>T,NM_144991.2:c.303+5692G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.909,\N,\N,TSPEAR
506731,21:45982034:A>G,NM_144991.2:c.303+5635T>C,\N,\N,2/11,Benign,\N,intron_variant,5.999,0.0061,1KG_SAS_AF,TSPEAR
506732,21:45982039:C>T,NM_144991.2:c.303+5630G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,8.536,\N,\N,TSPEAR
506733,21:45982114:A>G,NM_144991.2:c.303+5555T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,3.395,\N,\N,TSPEAR
506734,21:45982136:A>G,NM_144991.2:c.303+5533T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.045,0.0023,1KG_AFR_AF,TSPEAR
506735,21:45982139:T>C,NM_144991.2:c.303+5530A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.179,\N,\N,TSPEAR
506736,21:45982146:A>G,NM_144991.2:c.303+5523T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.47,0.0014,1KG_AMR_AF,TSPEAR
506737,21:45982162:G>C,NM_144991.2:c.303+5507C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.011,0.0008,1KG_AFR_AF,TSPEAR
506738,21:45982167:G>A,NM_144991.2:c.303+5502C>T,\N,\N,2/11,Benign,\N,intron_variant,5.059,0.031,1KG_AFR_AF,TSPEAR
506739,21:45982187:A>G,NM_144991.2:c.303+5482T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,9.988,\N,\N,TSPEAR
506740,21:45982204:G>A,NM_144991.2:c.303+5465C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,10.07,\N,\N,TSPEAR
506741,21:45982311:T>C,NM_144991.2:c.303+5358A>G,\N,\N,2/11,Benign,\N,intron_variant,10.78,0.0726,1KG_AFR_AF,TSPEAR
506742,21:45982318:C>T,NM_144991.2:c.303+5351G>A,\N,\N,2/11,Benign,\N,intron_variant,12.5,0.0089,1KG_EAS_AF,TSPEAR
506743,21:45982334:T>C,NM_144991.2:c.303+5335A>G,\N,\N,2/11,Benign,\N,intron_variant,14.99,0.0092,1KG_SAS_AF,TSPEAR
506744,21:45982337:C>T,NM_144991.2:c.303+5332G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,16.65,\N,\N,TSPEAR
506745,21:45982345:A>C,NM_144991.2:c.303+5324T>G,\N,\N,2/11,Benign,\N,intron_variant,15.25,0.9553,1KG_EUR_AF,TSPEAR
506746,21:45982349:A>T,NM_144991.2:c.303+5320T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,15.37,0.002,1KG_SAS_AF,TSPEAR
506747,21:45982352:T>C,NM_144991.2:c.303+5317A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,17.55,\N,\N,TSPEAR
506748,21:45982361:T>C,NM_144991.2:c.303+5308A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,16.38,0.001,1KG_EAS_AF,TSPEAR
506749,21:45982437:C>T,NM_144991.2:c.303+5232G>A,\N,\N,2/11,Benign,\N,intron_variant,2.928,0.0113,1KG_AFR_AF,TSPEAR
506750,21:45982479:CAAG>C,NM_144991.2:c.303+5187_303+5189del,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
506751,21:45982480:A>G,NM_144991.2:c.303+5189T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.222,0.0008,1KG_AFR_AF,TSPEAR
506752,21:45982508:A>G,NM_144991.2:c.303+5161T>C,\N,\N,2/11,Benign,\N,intron_variant,12.8,0.0408,1KG_AFR_AF,TSPEAR
506753,21:45982527:G>C,NM_144991.2:c.303+5142C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,15.81,0.0014,1KG_AMR_AF,TSPEAR
506754,21:45982540:A>C,NM_144991.2:c.303+5129T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,15.3,0.0023,1KG_AFR_AF,TSPEAR
506755,21:45982563:A>G,NM_144991.2:c.303+5106T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,14.51,\N,\N,TSPEAR
506756,21:45982590:T>C,NM_144991.2:c.303+5079A>G,\N,\N,2/11,Benign,\N,intron_variant,10.51,0.007,1KG_EUR_AF,TSPEAR
506757,21:45982592:A>G,NM_144991.2:c.303+5077T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,11.13,\N,\N,TSPEAR
506758,21:45982596:T>C,NM_144991.2:c.303+5073A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,11.16,\N,\N,TSPEAR
506759,21:45982606:G>A,NM_144991.2:c.303+5063C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,12.85,0.0014,1KG_AMR_AF,TSPEAR
506760,21:45982622:A>G,NM_144991.2:c.303+5047T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,7.086,0.001,1KG_EUR_AF,TSPEAR
506761,21:45982631:A>G,NM_144991.2:c.303+5038T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,2.94,0.0031,1KG_SAS_AF,TSPEAR
506762,21:45982652:G>A,NM_144991.2:c.303+5017C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,6.554,0.001,1KG_EUR_AF,TSPEAR
506763,21:45982716:A>G,NM_144991.2:c.303+4953T>C,\N,\N,2/11,Benign,\N,intron_variant,4.247,0.0726,1KG_AFR_AF,TSPEAR
506764,21:45982737:C>T,NM_144991.2:c.303+4932G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.433,0.001,1KG_SAS_AF,TSPEAR
506765,21:45982750:C>T,NM_144991.2:c.303+4919G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.257,0.0008,1KG_AFR_AF,TSPEAR
506766,21:45982755:C>T,NM_144991.2:c.303+4914G>A,\N,\N,2/11,Benign,\N,intron_variant,2.911,0.031,1KG_AFR_AF,TSPEAR
506767,21:45982756:G>A,NM_144991.2:c.303+4913C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,6.664,0.001,1KG_EAS_AF,TSPEAR
506768,21:45982767:G>C,NM_144991.2:c.303+4902C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,5.883,\N,\N,TSPEAR
506769,21:45982798:CA>C,NM_144991.2:c.303+4870del,\N,\N,2/11,Benign,\N,intron_variant,12.69,0.0159,1KG_EAS_AF,TSPEAR
506770,21:45982839:T>C,NM_144991.2:c.303+4830A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,9.27,0.001,1KG_EAS_AF,TSPEAR
506771,21:45982860:A>G,NM_144991.2:c.303+4809T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.464,0.004,1KG_EAS_AF,TSPEAR
506772,21:45982898:A>T,NM_144991.2:c.303+4771T>A,\N,\N,2/11,Benign,\N,intron_variant,8.261,0.0091,1KG_AFR_AF,TSPEAR
506773,21:45982908:G>A,NM_144991.2:c.303+4761C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.956,0.0023,1KG_AFR_AF,TSPEAR
506774,21:45982923:G>T,NM_144991.2:c.303+4746C>A,\N,\N,2/11,Benign,\N,intron_variant,1.16,0.9553,1KG_EUR_AF,TSPEAR
506775,21:45982932:A>G,NM_144991.2:c.303+4737T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,6.547,\N,\N,TSPEAR
506776,21:45982933:T>C,NM_144991.2:c.303+4736A>G,\N,\N,2/11,Benign,\N,intron_variant,4.787,0.0159,1KG_EAS_AF,TSPEAR
506777,21:45982975:G>A,NM_144991.2:c.303+4694C>T,\N,\N,2/11,Benign,\N,intron_variant,9.059,0.0099,1KG_EUR_AF,TSPEAR
506778,21:45982994:G>T,NM_144991.2:c.303+4675C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.167,\N,\N,TSPEAR
506779,21:45982998:T>C,NM_144991.2:c.303+4671A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.337,\N,\N,TSPEAR
506780,21:45983002:G>A,NM_144991.2:c.303+4667C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.372,0.001,1KG_SAS_AF,TSPEAR
506781,21:45983048:A>T,NM_144991.2:c.303+4621T>A,\N,\N,2/11,Benign,\N,intron_variant,15.81,0.0086,1KG_AMR_AF,TSPEAR
506782,21:45983050:TGAA>T,NM_144991.2:c.303+4616_303+4618del,\N,\N,2/11,Benign,\N,intron_variant,18.56,0.0083,1KG_AFR_AF,TSPEAR
506783,21:45983110:T>TC,NM_144991.2:c.303+4558dup,\N,\N,2/11,Benign,\N,intron_variant,15.75,0.053,1KG_AFR_AF,TSPEAR
506784,21:45983112:T>A,NM_144991.2:c.303+4557A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,17,0.0008,1KG_AFR_AF,TSPEAR
506785,21:45983122:G>T,NM_144991.2:c.303+4547C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,13.95,0.0008,1KG_AFR_AF,TSPEAR
506786,21:45983207:T>C,NM_144991.2:c.303+4462A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,13.44,\N,\N,TSPEAR
506787,21:45983222:A>C,NM_144991.2:c.303+4447T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,6.382,0.001,1KG_SAS_AF,TSPEAR
506788,21:45983271:T>A,NM_144991.2:c.303+4398A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,17.61,0.0043,1KG_AMR_AF,TSPEAR
506789,21:45983328:T>C,NM_144991.2:c.303+4341A>G,\N,\N,2/11,Benign,\N,intron_variant,7.864,0.2485,1KG_EUR_AF,TSPEAR
506790,21:45983365:T>C,NM_144991.2:c.303+4304A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,13.95,\N,\N,TSPEAR
506791,21:45983380:G>C,NM_144991.2:c.303+4289C>G,\N,\N,2/11,Benign,\N,intron_variant,13.57,0.0998,1KG_AFR_AF,TSPEAR
506792,21:45983401:A>G,NM_144991.2:c.303+4268T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,12.19,\N,\N,TSPEAR
506793,21:45983430:T>C,NM_144991.2:c.303+4239A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,5.214,0.0023,1KG_AFR_AF,TSPEAR
506794,21:45983448:A>C,NM_144991.2:c.303+4221T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.051,0.001,1KG_EUR_AF,TSPEAR
506795,21:45983449:A>C,NM_144991.2:c.303+4220T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.216,0.001,1KG_EUR_AF,TSPEAR
506796,21:45983471:C>CA,NM_144991.2:c.303+4197dup,\N,\N,2/11,Benign,\N,intron_variant,0.994,0.5239,1KG_EUR_AF,TSPEAR
506797,21:45983471:C>CAA,NM_144991.2:c.303+4196_303+4197dup,\N,\N,2/11,Benign,\N,intron_variant,0.909,0.0545,1KG_AFR_AF,TSPEAR
506798,21:45983490:C>T,NM_144991.2:c.303+4179G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.027,0.0023,1KG_AFR_AF,TSPEAR
506799,21:45983564:T>C,NM_144991.2:c.303+4105A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.379,\N,\N,TSPEAR
506800,21:45983580:C>T,NM_144991.2:c.303+4089G>A,\N,\N,2/11,Benign,\N,intron_variant,1.043,0.0408,1KG_AFR_AF,TSPEAR
506801,21:45983582:T>A,NM_144991.2:c.303+4087A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.588,\N,\N,TSPEAR
506802,21:45983590:T>C,NM_144991.2:c.303+4079A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.397,0.0015,1KG_AFR_AF,TSPEAR
506803,21:45983598:A>G,NM_144991.2:c.303+4071T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.479,\N,\N,TSPEAR
506804,21:45983639:A>G,NM_144991.2:c.303+4030T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.711,\N,\N,TSPEAR
506805,21:45983653:T>C,NM_144991.2:c.303+4016A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.556,0.002,1KG_EAS_AF,TSPEAR
506806,21:45983695:G>A,NM_144991.2:c.303+3974C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.535,0.001,1KG_SAS_AF,TSPEAR
506807,21:45983706:A>G,NM_144991.2:c.303+3963T>C,\N,\N,2/11,Benign,\N,intron_variant,0.75,0.9553,1KG_EUR_AF,TSPEAR
506808,21:45983722:G>C,NM_144991.2:c.303+3947C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.117,\N,\N,TSPEAR
506809,21:45983753:G>A,NM_144991.2:c.303+3916C>T,\N,\N,2/11,Benign,\N,intron_variant,0.617,0.006,1KG_EAS_AF,TSPEAR
506810,21:45983766:T>G,NM_144991.2:c.303+3903A>C,\N,\N,2/11,Benign,\N,intron_variant,0.772,0.2505,1KG_EUR_AF,TSPEAR
506811,21:45983770:T>C,NM_144991.2:c.303+3899A>G,\N,\N,2/11,Benign,\N,intron_variant,0.58,0.0144,1KG_AFR_AF,TSPEAR
506812,21:45983800:C>A,NM_144991.2:c.303+3869G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.331,\N,\N,TSPEAR
506813,21:45983812:C>T,NM_144991.2:c.303+3857G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.04,0.0014,1KG_AMR_AF,TSPEAR
506814,21:45983813:A>G,NM_144991.2:c.303+3856T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.757,\N,\N,TSPEAR
506815,21:45983845:C>T,NM_144991.2:c.303+3824G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.158,\N,\N,TSPEAR
506816,21:45983849:C>G,NM_144991.2:c.303+3820G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.685,0.001,1KG_SAS_AF,TSPEAR
506817,21:45983860:C>A,NM_144991.2:c.303+3809G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.149,\N,\N,TSPEAR
506818,21:45983895:C>A,NM_144991.2:c.303+3774G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.585,0.001,1KG_EAS_AF,TSPEAR
506819,21:45983937:AC>A,NM_144991.2:c.303+3731del,\N,\N,2/11,Unknown significance,\N,intron_variant,0.616,\N,\N,TSPEAR
506820,21:45983938:CA>C,NM_144991.2:c.303+3730del,\N,\N,2/11,Benign,\N,intron_variant,5.005,0.9543,1KG_EUR_AF,TSPEAR
506821,21:45983939:A>C,NM_144991.2:c.303+3730T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.128,\N,\N,TSPEAR
506822,21:45983968:G>A,NM_144991.2:c.303+3701C>T,\N,\N,2/11,Benign,\N,intron_variant,1.091,0.0151,1KG_AFR_AF,TSPEAR
506823,21:45983968:G>T,NM_144991.2:c.303+3701C>A,\N,\N,2/11,Benign,\N,intron_variant,0.364,0.031,1KG_AFR_AF,TSPEAR
506824,21:45983992:C>T,NM_144991.2:c.303+3677G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.631,\N,\N,TSPEAR
506825,21:45984007:T>C,NM_144991.2:c.303+3662A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.645,0.001,1KG_EAS_AF,TSPEAR
506826,21:45984020:AT>A,NM_144991.2:c.303+3648del,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
506827,21:45984072:C>A,NM_144991.2:c.303+3597G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.539,0.0014,1KG_AMR_AF,TSPEAR
506828,21:45984074:A>G,NM_144991.2:c.303+3595T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.434,0.0008,1KG_AFR_AF,TSPEAR
506829,21:45984086:G>A,NM_144991.2:c.303+3583C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.989,0.001,1KG_SAS_AF,TSPEAR
506830,21:45984091:T>C,NM_144991.2:c.303+3578A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.976,\N,\N,TSPEAR
506831,21:45984107:T>A,NM_144991.2:c.303+3562A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,4.038,0.001,1KG_SAS_AF,TSPEAR
506832,21:45984151:T>C,NM_144991.2:c.303+3518A>G,\N,\N,2/11,Benign,\N,intron_variant,0.581,0.0091,1KG_AFR_AF,TSPEAR
506833,21:45984187:A>C,NM_144991.2:c.303+3482T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.245,0.0008,1KG_AFR_AF,TSPEAR
506834,21:45984234:T>A,NM_144991.2:c.303+3435A>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.419,\N,\N,TSPEAR
506835,21:45984259:A>G,NM_144991.2:c.303+3410T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.557,0.001,1KG_EUR_AF,TSPEAR
506836,21:45984262:C>T,NM_144991.2:c.303+3407G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.117,\N,\N,TSPEAR
506837,21:45984275:G>A,NM_144991.2:c.303+3394C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.943,0.0014,1KG_AMR_AF,TSPEAR
506838,21:45984279:T>G,NM_144991.2:c.303+3390A>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.284,0.0014,1KG_AMR_AF,TSPEAR
506839,21:45984284:A>G,NM_144991.2:c.303+3385T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.882,\N,\N,TSPEAR
506840,21:45984289:G>C,NM_144991.2:c.303+3380C>G,\N,\N,2/11,Benign,\N,intron_variant,0.118,0.9553,1KG_EUR_AF,TSPEAR
506841,21:45984332:A>T,NM_144991.2:c.303+3337T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.767,\N,\N,TSPEAR
506842,21:45984339:C>A,NM_144991.2:c.303+3330G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.197,0.0031,1KG_SAS_AF,TSPEAR
506843,21:45984378:C>T,NM_144991.2:c.303+3291G>A,\N,\N,2/11,Benign,\N,intron_variant,0.597,0.0058,1KG_AMR_AF,TSPEAR
506844,21:45984379:GATAAA>G,NM_144991.2:c.303+3285_303+3289del,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
506845,21:45984422:A>G,NM_144991.2:c.303+3247T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.391,\N,\N,TSPEAR
506846,21:45984446:G>A,NM_144991.2:c.303+3223C>T,\N,\N,2/11,Benign,\N,intron_variant,0.916,0.0089,1KG_EUR_AF,TSPEAR
506847,21:45984448:C>G,NM_144991.2:c.303+3221G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.746,0.001,1KG_SAS_AF,TSPEAR
506848,21:45984454:A>G,NM_144991.2:c.303+3215T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.94,0.0015,1KG_AFR_AF,TSPEAR
506849,21:45984462:G>C,NM_144991.2:c.303+3207C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.115,\N,\N,TSPEAR
506850,21:45984514:T>C,NM_144991.2:c.303+3155A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.584,0.001,1KG_EUR_AF|1KG_SAS_AF,TSPEAR
506851,21:45984552:A>T,NM_144991.2:c.303+3117T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.25,\N,\N,TSPEAR
506852,21:45984571:A>G,NM_144991.2:c.303+3098T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.012,0.001,1KG_SAS_AF,TSPEAR
506853,21:45984585:G>A,NM_144991.2:c.303+3084C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.514,0.0038,1KG_AFR_AF,TSPEAR
506854,21:45984599:C>T,NM_144991.2:c.303+3070G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.751,0.0008,1KG_AFR_AF,TSPEAR
506855,21:45984600:G>A,NM_144991.2:c.303+3069C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.887,0.001,1KG_EAS_AF|1KG_EUR_AF,TSPEAR
506856,21:45984643:T>C,NM_144991.2:c.303+3026A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.655,\N,\N,TSPEAR
506857,21:45984663:AAGTCTAGCAG>A,NM_144991.2:c.303+2996_303+3005del,\N,\N,2/11,Unknown significance,\N,intron_variant,1.242,0.002,1KG_EUR_AF,TSPEAR
506858,21:45984670:G>T,NM_144991.2:c.303+2999C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.326,0.0015,1KG_AFR_AF,TSPEAR
506859,21:45984708:A>T,NM_144991.2:c.303+2961T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.307,\N,\N,TSPEAR
506860,21:45984748:C>G,NM_144991.2:c.303+2921G>C,\N,\N,2/11,Benign,\N,intron_variant,0.652,0.9553,1KG_EUR_AF,TSPEAR
506861,21:45984760:G>A,NM_144991.2:c.303+2909C>T,\N,\N,2/11,Benign,\N,intron_variant,1.073,0.0726,1KG_AFR_AF,TSPEAR
506862,21:45984800:A>G,NM_144991.2:c.303+2869T>C,\N,\N,2/11,Benign,\N,intron_variant,0.496,0.007,1KG_EUR_AF,TSPEAR
506863,21:45984812:A>C,NM_144991.2:c.303+2857T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.36,0.004,1KG_EAS_AF,TSPEAR
506864,21:45984819:T>C,NM_144991.2:c.303+2850A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.716,0.0041,1KG_SAS_AF,TSPEAR
506865,21:45984833:T>C,NM_144991.2:c.303+2836A>G,\N,\N,2/11,Benign,\N,intron_variant,0.499,0.3919,1KG_EAS_AF,TSPEAR
506866,21:45984915:TAACC>T,NM_144991.2:c.303+2750_303+2753del,\N,\N,2/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
506867,21:45984942:C>T,NM_144991.2:c.303+2727G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.82,0.0015,1KG_AFR_AF,TSPEAR
506868,21:45984965:T>C,NM_144991.2:c.303+2704A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.529,0.0008,1KG_AFR_AF,TSPEAR
506869,21:45984982:G>A,NM_144991.2:c.303+2687C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.7,0.002,1KG_SAS_AF,TSPEAR
506870,21:45985013:A>G,NM_144991.2:c.303+2656T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.112,\N,\N,TSPEAR
506871,21:45985047:G>A,NM_144991.2:c.303+2622C>T,\N,\N,2/11,Benign,\N,intron_variant,0.63,0.4221,1KG_AFR_AF,TSPEAR
506872,21:45985062:A>G,NM_144991.2:c.303+2607T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.832,\N,\N,TSPEAR
506873,21:45985099:G>T,NM_144991.2:c.303+2570C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.271,0.0015,1KG_AFR_AF,TSPEAR
506874,21:45985109:AAAG>A,NM_144991.2:c.303+2557_303+2559del,\N,\N,2/11,Benign,\N,intron_variant,0.15,0.0469,1KG_AFR_AF,TSPEAR
506875,21:45985121:A>C,NM_144991.2:c.303+2548T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.496,0.0014,1KG_AMR_AF,TSPEAR
506876,21:45985137:A>G,NM_144991.2:c.303+2532T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.128,\N,\N,TSPEAR
506877,21:45985228:C>T,NM_144991.2:c.303+2441G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.43,0.001,1KG_EAS_AF,TSPEAR
506878,21:45985243:T>C,NM_144991.2:c.303+2426A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.301,0.0008,1KG_AFR_AF,TSPEAR
506879,21:45985263:C>T,NM_144991.2:c.303+2406G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.416,0.002,1KG_EUR_AF,TSPEAR
506880,21:45985337:T>C,NM_144991.2:c.303+2332A>G,\N,\N,2/11,Benign,\N,intron_variant,0.426,0.8423,1KG_EAS_AF,TSPEAR
506881,21:45985338:G>A,NM_144991.2:c.303+2331C>T,\N,\N,2/11,Benign,\N,intron_variant,0.906,0.0266,1KG_SAS_AF,TSPEAR
506882,21:45985364:A>G,NM_144991.2:c.303+2305T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.644,0.001,1KG_SAS_AF,TSPEAR
506883,21:45985376:C>A,NM_144991.2:c.303+2293G>T,\N,\N,2/11,Benign,\N,intron_variant,2.516,0.0129,1KG_EAS_AF,TSPEAR
506884,21:45985448:TA>T,NM_144991.2:c.303+2220del,\N,\N,2/11,Unknown significance,\N,intron_variant,4.313,0.0023,1KG_AFR_AF,TSPEAR
506885,21:45985477:C>A,NM_144991.2:c.303+2192G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.059,0.004,1KG_EAS_AF,TSPEAR
506886,21:45985485:TA>T,NM_144991.2:c.303+2183del,\N,\N,2/11,Benign,\N,intron_variant,6.045,0.0121,1KG_AFR_AF,TSPEAR
506887,21:45985508:A>G,NM_144991.2:c.303+2161T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.975,0.002,1KG_EUR_AF,TSPEAR
506888,21:45985515:T>C,NM_144991.2:c.303+2154A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.865,0.0008,1KG_AFR_AF,TSPEAR
506889,21:45985532:G>C,NM_144991.2:c.303+2137C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.159,\N,\N,TSPEAR
506890,21:45985558:A>G,NM_144991.2:c.303+2111T>C,\N,\N,2/11,Benign,\N,intron_variant,0.421,0.8423,1KG_EAS_AF,TSPEAR
506891,21:45985640:A>C,NM_144991.2:c.303+2029T>G,\N,\N,2/11,Benign,\N,intron_variant,0.219,0.007,1KG_EUR_AF,TSPEAR
506892,21:45985686:C>T,NM_144991.2:c.303+1983G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.764,0.001,1KG_EAS_AF,TSPEAR
506893,21:45985715:T>C,NM_144991.2:c.303+1954A>G,\N,\N,2/11,Benign,\N,intron_variant,0.484,0.0164,1KG_SAS_AF,TSPEAR
506894,21:45985783:C>T,NM_144991.2:c.303+1886G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.894,0.0045,1KG_AFR_AF,TSPEAR
506895,21:45985808:T>C,NM_144991.2:c.303+1861A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.544,\N,\N,TSPEAR
506896,21:45985837:G>A,NM_144991.2:c.303+1832C>T,\N,\N,2/11,Benign,\N,intron_variant,1.176,0.005,1KG_EUR_AF,TSPEAR
506897,21:45985859:C>T,NM_144991.2:c.303+1810G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.781,0.001,1KG_EUR_AF,TSPEAR
506898,21:45985879:A>G,NM_144991.2:c.303+1790T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.65,\N,\N,TSPEAR
506899,21:45985883:C>G,NM_144991.2:c.303+1786G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.441,\N,\N,TSPEAR
506900,21:45985883:C>T,NM_144991.2:c.303+1786G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.934,0.001,1KG_EAS_AF,TSPEAR
506901,21:45985884:G>A,NM_144991.2:c.303+1785C>T,\N,\N,2/11,Benign,\N,intron_variant,0.642,0.0741,1KG_AFR_AF,TSPEAR
506902,21:45985888:C>T,NM_144991.2:c.303+1781G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.063,\N,\N,TSPEAR
506903,21:45985922:G>A,NM_144991.2:c.303+1747C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.06,\N,\N,TSPEAR
506904,21:45985978:G>A,NM_144991.2:c.303+1691C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.523,\N,\N,TSPEAR
506905,21:45985999:G>A,NM_144991.2:c.303+1670C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.336,0.004,1KG_EUR_AF,TSPEAR
506906,21:45986011:C>T,NM_144991.2:c.303+1658G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.246,\N,\N,TSPEAR
506907,21:45986016:T>C,NM_144991.2:c.303+1653A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.839,\N,\N,TSPEAR
506908,21:45986019:C>T,NM_144991.2:c.303+1650G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.157,\N,\N,TSPEAR
506909,21:45986021:C>A,NM_144991.2:c.303+1648G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.458,0.0008,1KG_AFR_AF,TSPEAR
506910,21:45986033:A>C,NM_144991.2:c.303+1636T>G,\N,\N,2/11,Benign,\N,intron_variant,0.662,0.0208,1KG_EAS_AF,TSPEAR
506911,21:45986083:C>T,NM_144991.2:c.303+1586G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,0.662,\N,\N,TSPEAR
506912,21:45986084:G>A,NM_144991.2:c.303+1585C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.9,0.001,1KG_SAS_AF,TSPEAR
506913,21:45986092:T>C,NM_144991.2:c.303+1577A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.572,\N,\N,TSPEAR
506914,21:45986101:G>A,NM_144991.2:c.303+1568C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.876,\N,\N,TSPEAR
506915,21:45986102:CA>C,NM_144991.2:c.303+1566del,\N,\N,2/11,Benign,\N,intron_variant,2.223,0.0227,1KG_AFR_AF,TSPEAR
506916,21:45986159:A>G,NM_144991.2:c.303+1510T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.848,\N,\N,TSPEAR
506917,21:45986203:A>G,NM_144991.2:c.303+1466T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.593,0.0008,1KG_AFR_AF,TSPEAR
506918,21:45986254:G>A,NM_144991.2:c.303+1415C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.263,\N,\N,TSPEAR
506919,21:45986268:T>C,NM_144991.2:c.303+1401A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.7,\N,\N,TSPEAR
506920,21:45986342:G>C,NM_144991.2:c.303+1327C>G,\N,\N,2/11,Benign,\N,intron_variant,0.11,0.0537,1KG_AFR_AF,TSPEAR
506921,21:45986347:A>G,NM_144991.2:c.303+1322T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.576,\N,\N,TSPEAR
506922,21:45986351:C>T,NM_144991.2:c.303+1318G>A,\N,\N,2/11,Benign,\N,intron_variant,0.952,0.2465,1KG_EUR_AF,TSPEAR
506923,21:45986396:A>G,NM_144991.2:c.303+1273T>C,\N,\N,2/11,Benign,\N,intron_variant,1.996,0.0227,1KG_AFR_AF,TSPEAR
506924,21:45986422:A>T,NM_144991.2:c.303+1247T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.999,\N,\N,TSPEAR
506925,21:45986441:A>G,NM_144991.2:c.303+1228T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,5.329,\N,\N,TSPEAR
506926,21:45986458:A>T,NM_144991.2:c.303+1211T>A,\N,\N,2/11,Benign,\N,intron_variant,6.92,0.0356,1KG_AFR_AF,TSPEAR
506927,21:45986474:A>G,NM_144991.2:c.303+1195T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,7.698,0.0043,1KG_AMR_AF,TSPEAR
506928,21:45986475:A>G,NM_144991.2:c.303+1194T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,8.491,0.0008,1KG_AFR_AF,TSPEAR
506929,21:45986506:A>C,NM_144991.2:c.303+1163T>G,\N,\N,2/11,Benign,\N,intron_variant,6.235,0.0102,1KG_SAS_AF,TSPEAR
506930,21:45986520:G>C,NM_144991.2:c.303+1149C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,5.575,0.001,1KG_EAS_AF,TSPEAR
506931,21:45986547:A>T,NM_144991.2:c.303+1122T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.446,\N,\N,TSPEAR
506932,21:45986590:C>T,NM_144991.2:c.303+1079G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.437,\N,\N,TSPEAR
506933,21:45986600:A>G,NM_144991.2:c.303+1069T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,6.255,0.001,1KG_SAS_AF,TSPEAR
506934,21:45986632:A>T,NM_144991.2:c.303+1037T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.935,\N,\N,TSPEAR
506935,21:45986636:T>C,NM_144991.2:c.303+1033A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,5.485,0.0015,1KG_AFR_AF,TSPEAR
506936,21:45986651:A>G,NM_144991.2:c.303+1018T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,8.158,\N,\N,TSPEAR
506937,21:45986659:C>T,NM_144991.2:c.303+1010G>A,\N,\N,2/11,Benign,\N,intron_variant,9.373,0.0092,1KG_SAS_AF,TSPEAR
506938,21:45986672:G>A,NM_144991.2:c.303+997C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,9.664,\N,\N,TSPEAR
506939,21:45986677:G>A,NM_144991.2:c.303+992C>T,\N,\N,2/11,Benign,\N,intron_variant,10.05,0.0328,1KG_EUR_AF,TSPEAR
506940,21:45986710:T>C,NM_144991.2:c.303+959A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,8.382,\N,\N,TSPEAR
506941,21:45986725:A>G,NM_144991.2:c.303+944T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,8.42,\N,\N,TSPEAR
506942,21:45986728:C>G,NM_144991.2:c.303+941G>C,\N,\N,2/11,Unknown significance,\N,intron_variant,6.734,\N,\N,TSPEAR
506943,21:45986728:C>T,NM_144991.2:c.303+941G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,7.954,\N,\N,TSPEAR
506944,21:45986778:T>C,NM_144991.2:c.303+891A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,10.69,\N,\N,TSPEAR
506945,21:45986832:C>T,NM_144991.2:c.303+837G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,9.807,\N,\N,TSPEAR
506946,21:45986848:A>G,NM_144991.2:c.303+821T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,7.304,0.0008,1KG_AFR_AF,TSPEAR
506947,21:45986870:C>T,NM_144991.2:c.303+799G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.897,\N,\N,TSPEAR
506948,21:45986875:TA>T,NM_144991.2:c.303+793del,\N,\N,2/11,Benign,\N,intron_variant,1.1,0.0109,1KG_EAS_AF,TSPEAR
506949,21:45986883:A>G,NM_144991.2:c.303+786T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,0.031,0.0015,1KG_AFR_AF,TSPEAR
506950,21:45986887:A>G,NM_144991.2:c.303+782T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.389,\N,\N,TSPEAR
506951,21:45986892:T>C,NM_144991.2:c.303+777A>G,\N,\N,2/11,Benign,\N,intron_variant,1.548,0.0121,1KG_AFR_AF,TSPEAR
506952,21:45986932:G>A,NM_144991.2:c.303+737C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,4.129,\N,\N,TSPEAR
506953,21:45986932:G>T,NM_144991.2:c.303+737C>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.039,0.001,1KG_EUR_AF,TSPEAR
506954,21:45986967:T>C,NM_144991.2:c.303+702A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.854,0.0023,1KG_AFR_AF,TSPEAR
506955,21:45987022:A>C,NM_144991.2:c.303+647T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.471,\N,\N,TSPEAR
506956,21:45987061:G>A,NM_144991.2:c.303+608C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.695,0.0008,1KG_AFR_AF,TSPEAR
506957,21:45987085:T>C,NM_144991.2:c.303+584A>G,\N,\N,2/11,Benign,\N,intron_variant,2.694,0.0197,1KG_AFR_AF,TSPEAR
506958,21:45987105:A>G,NM_144991.2:c.303+564T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.167,\N,\N,TSPEAR
506959,21:45987167:A>G,NM_144991.2:c.303+502T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,3.721,\N,\N,TSPEAR
506960,21:45987204:T>C,NM_144991.2:c.303+465A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.899,0.001,1KG_EAS_AF,TSPEAR
506961,21:45987208:G>A,NM_144991.2:c.303+461C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.443,\N,\N,TSPEAR
506962,21:45987226:C>T,NM_144991.2:c.303+443G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.81,\N,\N,TSPEAR
506963,21:45987228:TG>T,NM_144991.2:c.303+440del,\N,\N,2/11,Benign,\N,intron_variant,2.357,0.8413,1KG_EAS_AF,TSPEAR
506964,21:45987233:G>A,NM_144991.2:c.303+436C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.995,\N,\N,TSPEAR
506965,21:45987235:A>G,NM_144991.2:c.303+434T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,3.994,\N,\N,TSPEAR
506966,21:45987271:A>C,NM_144991.2:c.303+398T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,3.071,\N,\N,TSPEAR
506967,21:45987302:G>C,NM_144991.2:c.303+367C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.063,0.001,1KG_SAS_AF,TSPEAR
506968,21:45987327:A>T,NM_144991.2:c.303+342T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.734,\N,\N,TSPEAR
506969,21:45987390:C>T,NM_144991.2:c.303+279G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.145,0.0014,1KG_AMR_AF,TSPEAR
506970,21:45987391:G>A,NM_144991.2:c.303+278C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1,\N,\N,TSPEAR
506971,21:45987406:A>G,NM_144991.2:c.303+263T>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.403,0.0014,1KG_AMR_AF,TSPEAR
506972,21:45987422:T>C,NM_144991.2:c.303+247A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,1.777,0.0014,1KG_AMR_AF,TSPEAR
506973,21:45987451:T>C,NM_144991.2:c.303+218A>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.248,0.0014,1KG_AMR_AF,TSPEAR
506974,21:45987482:A>T,NM_144991.2:c.303+187T>A,\N,\N,2/11,Unknown significance,\N,intron_variant,4.067,0.001,1KG_EAS_AF,TSPEAR
506975,21:45987491:C>T,NM_144991.2:c.303+178G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,3.161,0.001,1KG_SAS_AF,TSPEAR
506976,21:45987564:G>A,NM_144991.2:c.303+105C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.176,0.0008,1KG_AFR_AF,TSPEAR
506977,21:45987579:C>T,NM_144991.2:c.303+90G>A,\N,\N,2/11,Benign,\N,intron_variant,2.645,0.0484,1KG_AFR_AF,TSPEAR
506978,21:45987580:G>A,NM_144991.2:c.303+89C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,1.792,0.0008,1KG_AFR_AF,TSPEAR
506979,21:45987614:C>A,NM_144991.2:c.303+55G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,4.043,0.001,1KG_SAS_AF,TSPEAR
506980,21:45987614:C>T,NM_144991.2:c.303+55G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.653,\N,\N,TSPEAR
506981,21:45987622:G>A,NM_144991.2:c.303+47C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.827,0.000126646,EXAC_EAS_AF,TSPEAR
506982,21:45987628:A>C,NM_144991.2:c.303+41T>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.892,0.0000161812,EXAC_NFE_AF,TSPEAR
506983,21:45987632:C>A,NM_144991.2:c.303+37G>T,\N,\N,2/11,Unknown significance,\N,intron_variant,0.815,\N,\N,TSPEAR
506984,21:45987633:G>C,NM_144991.2:c.303+36C>G,\N,\N,2/11,Unknown significance,\N,intron_variant,0.865,0.0000161614,EXAC_NFE_AF,TSPEAR
506985,21:45987638:T>G,NM_144991.2:c.303+31A>C,\N,\N,2/11,Benign,\N,intron_variant,3.073,0.00712808,EXAC_SAS_AF,TSPEAR
506986,21:45987645:C>T,NM_144991.2:c.303+24G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,1.477,0.0000892857,EXAC_AMR_AF,TSPEAR
506987,21:45987646:G>A,NM_144991.2:c.303+23C>T,\N,\N,2/11,Unknown significance,\N,intron_variant,2.023,0.000101112,EXAC_AFR_AF,TSPEAR
506988,21:45987650:T>G,NM_144991.2:c.303+19A>C,\N,\N,2/11,Unknown significance,\N,intron_variant,1.918,0.000702952,EXAC_AFR_AF,TSPEAR
506989,21:45987652:C>T,NM_144991.2:c.303+17G>A,\N,\N,2/11,Unknown significance,\N,intron_variant,2.06,0.0000157674,EXAC_NFE_AF,TSPEAR
506990,21:45987665:T>C,NM_144991.2:c.303+4A>G,\N,\N,2/11,Unknown significance,\N,splice_region_variant&intron_variant,6.907,0.000438135,EXAC_AMR_AF,TSPEAR
506991,21:45987667:AC>A,NM_144991.2:c.303+1del,\N,\N,2/11,Unknown significance,\N,splice_donor_variant,22.1,0.0000156333,EXAC_NFE_AF,TSPEAR
506992,21:45987674:G>A,NM_144991.2:c.298C>T,NP_659428.2:p.Pro100Ser,2/12,\N,Likely benign,\N,missense_variant,5.906,\N,\N,TSPEAR
506993,21:45987680:G>T,NM_144991.2:c.292C>A,NP_659428.2:p.Leu98Ile,2/12,\N,Unknown significance,\N,missense_variant,8.881,0.000116279,EVS_EA_AF,TSPEAR
506994,21:45987693:CA>C,NM_144991.2:c.278del,NP_659428.2:p.Leu93Ter,2/12,\N,Unknown significance,\N,frameshift_variant,24,0.000093006,EXAC_SAS_AF,TSPEAR
506995,21:45987704:C>T,NM_144991.2:c.268G>A,NP_659428.2:p.Val90Ile,2/12,\N,Likely benign,\N,missense_variant,13.86,0.0000868961,EXAC_AMR_AF,TSPEAR
506996,21:45987705:G>A,NM_144991.2:c.267C>T,NP_659428.2:p.Ile89=,2/12,\N,Unknown significance,\N,synonymous_variant,12.43,0.000115821,EXAC_EAS_AF,TSPEAR
506997,21:45987706:A>G,NM_144991.2:c.266T>C,NP_659428.2:p.Ile89Thr,2/12,\N,Unknown significance,\N,missense_variant,24.5,\N,\N,TSPEAR
506998,21:45987707:T>C,NM_144991.2:c.265A>G,NP_659428.2:p.Ile89Val,2/12,\N,Unknown significance,\N,missense_variant,11.98,0.000243467,EXAC_SAS_AF,TSPEAR
506999,21:45987720:A>C,NM_144991.2:c.252T>G,NP_659428.2:p.Pro84=,2/12,\N,Unknown significance,\N,synonymous_variant,0.13,0.0000967118,EXAC_AFR_AF,TSPEAR
507000,21:45987721:G>C,NM_144991.2:c.251C>G,NP_659428.2:p.Pro84Arg,2/12,\N,Unknown significance,\N,missense_variant,25.4,0.0000152509,EXAC_NFE_AF,TSPEAR
507001,21:45987722:G>A,NM_144991.2:c.250C>T,NP_659428.2:p.Pro84Ser,2/12,\N,Unknown significance,\N,missense_variant,26,0.0008,1KG_AFR_AF,TSPEAR
507002,21:45987736:T>G,NM_001272037.1:c.32A>C,NP_001258966.1:p.Gln11Pro,3/13,\N,Likely benign,\N,missense_variant,6.089,0.00266081,EXAC_EAS_AF,TSPEAR
507003,21:45987737:G>A,NM_144991.2:c.235C>T,NP_659428.2:p.Gln79Ter,2/12,\N,Unknown significance,\N,stop_gained,23.1,\N,\N,TSPEAR
507004,21:45987747:C>T,NM_144991.2:c.225G>A,NP_659428.2:p.Arg75=,2/12,\N,Unknown significance,\N,synonymous_variant,7.531,\N,\N,TSPEAR
507005,21:45987751:G>C,NM_144991.2:c.221C>G,NP_659428.2:p.Ser74Cys,2/12,\N,Unknown significance,\N,missense_variant,22.7,0.0000681106,EXAC_SAS_AF,TSPEAR
507006,21:45987763:C>T,NM_144991.2:c.209G>A,NP_659428.2:p.Ser70Asn,2/12,\N,Likely benign,\N,missense_variant,14.06,0.000116279,EVS_EA_AF,TSPEAR
507007,21:45987771:G>A,NM_144991.2:c.201C>T,NP_659428.2:p.Arg67=,2/12,\N,Unknown significance,\N,synonymous_variant,0.349,0.0000151474,EXAC_NFE_AF,TSPEAR
507008,21:45987772:C>CG,NM_144991.2:c.199dup,NP_659428.2:p.Arg67ProfsTer15,2/12,\N,Unknown significance,\N,frameshift_variant,\N,0.0000909532,EXAC_NFE_AF,TSPEAR
507009,21:45987772:C>T,NM_144991.2:c.200G>A,NP_659428.2:p.Arg67His,2/12,\N,Likely benign,\N,missense_variant,6.119,0.000545719,EXAC_NFE_AF,TSPEAR
507010,21:45987773:G>A,NM_144991.2:c.199C>T,NP_659428.2:p.Arg67Cys,2/12,\N,Unknown significance,\N,missense_variant,26.1,0.000478403,EXAC_SAS_AF,TSPEAR
507011,21:45987773:G>C,NM_144991.2:c.199C>G,NP_659428.2:p.Arg67Gly,2/12,\N,Unknown significance,\N,missense_variant,15.79,0.0014,1KG_AMR_AF,TSPEAR
507012,21:45987773:G>T,NM_144991.2:c.199C>A,NP_659428.2:p.Arg67Ser,2/12,\N,Unknown significance,\N,missense_variant,14.87,0.0000683434,EXAC_SAS_AF,TSPEAR
507013,21:45987775:G>A,NM_144991.2:c.197C>T,NP_659428.2:p.Pro66Leu,2/12,\N,Likely benign,\N,missense_variant,5.513,0.000116279,EVS_EA_AF,TSPEAR
507014,21:45987779:C>T,NM_144991.2:c.193G>A,NP_659428.2:p.Ala65Thr,2/12,\N,Benign,\N,missense_variant,5.254,0.0051,1KG_SAS_AF,TSPEAR
507015,21:45987780:G>A,NM_144991.2:c.192C>T,NP_659428.2:p.Ala64=,2/12,\N,Unknown significance,\N,synonymous_variant,6.648,0.00013725,EXAC_SAS_AF,TSPEAR
507016,21:45987788:A>G,NM_144991.2:c.184T>C,NP_659428.2:p.Ser62Pro,2/12,\N,Unknown significance,\N,missense_variant,23.6,0.0000303168,EXAC_NFE_AF,TSPEAR
507017,21:45987790:A>T,NM_144991.2:c.182T>A,NP_659428.2:p.Leu61His,2/12,\N,Unknown significance,\N,missense_variant,24.3,0.0000965624,EXAC_AFR_AF,TSPEAR
507018,21:45987802:C>T,NM_144991.2:c.170G>A,NP_659428.2:p.Arg57Gln,2/12,\N,Benign,\N,missense_variant,18.88,0.00706133,EXAC_AFR_AF,TSPEAR
507019,21:45987803:G>A,NM_144991.2:c.169C>T,NP_659428.2:p.Arg57Trp,2/12,\N,Unknown significance,\N,missense_variant,23,0.00484408,EXAC_FIN_AF,TSPEAR
507020,21:45987805:G>A,NM_144991.2:c.167C>T,NP_659428.2:p.Ala56Val,2/12,\N,Likely benign,\N,missense_variant,0.003,0.000045608,EXAC_NFE_AF,TSPEAR
507021,21:45987810:G>A,NM_144991.2:c.162C>T,NP_659428.2:p.His54=,2/12,\N,Unknown significance,\N,synonymous_variant,1.506,0.000116279,EVS_EA_AF,TSPEAR
507022,21:45987821:C>T,NM_144991.2:c.151G>A,NP_659428.2:p.Val51Ile,2/12,\N,Likely benign,\N,missense_variant,0.179,0.003,1KG_EUR_AF,TSPEAR
507023,21:45987824:T>C,NM_144991.2:c.148A>G,NP_659428.2:p.Ile50Val,2/12,\N,Likely benign,\N,missense_variant,0.001,0.0000152579,EXAC_NFE_AF,TSPEAR
507024,21:45987828:G>T,NM_144991.2:c.144C>A,NP_659428.2:p.Ile48=,2/12,\N,Unknown significance,\N,synonymous_variant,3.584,0.0000305567,EXAC_NFE_AF,TSPEAR
507025,21:45987834:G>A,NM_144991.2:c.138C>T,NP_659428.2:p.Ser46=,2/12,\N,Unknown significance,\N,synonymous_variant,7.655,0.00164873,EXAC_AMR_AF,TSPEAR
507026,21:45987837:T>C,NM_144991.2:c.135A>G,NP_659428.2:p.Thr45=,2/12,\N,Unknown significance,\N,synonymous_variant,0.005,0.000115982,EXAC_EAS_AF,TSPEAR
507027,21:45987838:G>A,NM_144991.2:c.134C>T,NP_659428.2:p.Thr45Ile,2/12,\N,Likely benign,\N,missense_variant,0.532,0.0000783945,EXAC_SAS_AF,TSPEAR
507028,21:45987841:G>A,NM_144991.2:c.131C>T,NP_659428.2:p.Ala44Val,2/12,\N,Likely benign,\N,missense_variant,9.044,0.001,1KG_EAS_AF,TSPEAR
507029,21:45987841:G>C,NM_144991.2:c.131C>G,NP_659428.2:p.Ala44Gly,2/12,\N,Likely benign,\N,missense_variant,6.254,0.000226963,EVS_AA_AF,TSPEAR
507030,21:45987843:G>A,NM_144991.2:c.129C>T,NP_659428.2:p.Gly43=,2/12,\N,Unknown significance,\N,synonymous_variant,6.405,0.0000307399,EXAC_NFE_AF,TSPEAR
507031,21:45987849:A>G,NM_144991.2:c.123T>C,NP_659428.2:p.Ser41=,2/12,\N,Unknown significance,\N,synonymous_variant,0.129,\N,\N,TSPEAR
507032,21:45987853:G>A,NM_144991.2:c.119C>T,NP_659428.2:p.Pro40Leu,2/12,\N,Unknown significance,\N,missense_variant,17.88,0.000232558,EVS_EA_AF,TSPEAR
507033,21:45987857:C>T,NM_144991.2:c.115G>A,NP_659428.2:p.Val39Ile,2/12,\N,Likely benign,\N,missense_variant,0.327,0.0000155294,EXAC_NFE_AF,TSPEAR
507034,21:45987864:C>T,NM_144991.2:c.108G>A,NP_659428.2:p.Ala36=,2/12,\N,Unknown significance,\N,synonymous_variant,12.3,\N,\N,TSPEAR
507035,21:45987865:G>A,NM_144991.2:c.107C>T,NP_659428.2:p.Ala36Val,2/12,\N,Unknown significance,\N,missense_variant,23.7,0.000226963,EVS_AA_AF,TSPEAR
507036,21:45987865:G>T,NM_144991.2:c.107C>A,NP_659428.2:p.Ala36Glu,2/12,\N,Unknown significance,\N,missense_variant,18.24,0.0000879198,EXAC_AMR_AF,TSPEAR
507037,21:45987874:T>G,NM_144991.2:c.98A>C,NP_659428.2:p.Asp33Ala,2/12,\N,Unknown significance,\N,missense_variant,24.5,0.000116279,EVS_EA_AF,TSPEAR
507038,21:45987876:CA>C,NM_144991.2:c.95del,NP_659428.2:p.Leu32ArgfsTer19,2/12,\N,Unknown significance,\N,frameshift_variant,29.8,0.000016086,EXAC_NFE_AF,TSPEAR
507039,21:45987880:G>T,NM_144991.2:c.92C>A,NP_659428.2:p.Pro31His,2/12,\N,Unknown significance,\N,missense_variant,24.9,0.0000906125,EXAC_AMR_AF,TSPEAR
507040,21:45987881:G>A,NM_144991.2:c.91C>T,NP_659428.2:p.Pro31Ser,2/12,\N,Unknown significance,\N,missense_variant,24.7,0.000106383,EXAC_SAS_AF,TSPEAR
507041,21:45987881:G>C,NM_144991.2:c.91C>G,NP_659428.2:p.Pro31Ala,2/12,\N,Unknown significance,\N,missense_variant,23.4,0.000106383,EXAC_SAS_AF,TSPEAR
507042,21:45987882:G>A,NM_144991.2:c.90C>T,NP_659428.2:p.Arg30=,2/12,\N,Unknown significance,\N,synonymous_variant,1.06,0.000116279,EVS_EA_AF,TSPEAR
507043,21:45987883:C>T,NM_144991.2:c.89G>A,NP_659428.2:p.Arg30His,2/12,\N,Likely benign,\N,missense_variant,16.73,0.000183385,EXAC_AMR_AF,TSPEAR
507044,21:45987884:G>A,NM_144991.2:c.88C>T,NP_659428.2:p.Arg30Cys,2/12,\N,Unknown significance,\N,missense_variant,23.9,0.000697674,EVS_EA_AF,TSPEAR
507045,21:45987887:G>A,NM_144991.2:c.85C>T,NP_659428.2:p.Leu29=,2/12,\N,Unknown significance,\N,splice_region_variant&synonymous_variant,10.31,0.0000331181,EXAC_NFE_AF,TSPEAR
507046,21:45987895:G>A,NM_144991.2:c.83-6C>T,\N,\N,1/11,Unknown significance,\N,splice_region_variant&intron_variant,0.327,0.001,1KG_EUR_AF,TSPEAR
507047,21:45987906:A>C,NM_144991.2:c.83-17T>G,\N,\N,1/11,Unknown significance,\N,intron_variant,4.079,0.0000356125,EXAC_NFE_AF,TSPEAR
507048,21:45987914:G>A,NM_144991.2:c.83-25C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.111,0.0000185536,EXAC_NFE_AF,TSPEAR
507049,21:45987914:G>T,NM_144991.2:c.83-25C>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.306,0.000166982,EXAC_NFE_AF,TSPEAR
507050,21:45987920:C>A,NM_144991.2:c.83-31G>T,\N,\N,1/11,Unknown significance,\N,intron_variant,5.511,0.0031,1KG_SAS_AF,TSPEAR
507051,21:45987927:A>AC,NM_144991.2:c.83-39dup,\N,\N,1/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
507052,21:45987928:C>T,NM_144991.2:c.83-39G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,2.413,0.002,1KG_EAS_AF,TSPEAR
507053,21:45987932:C>CAA,NM_144991.2:c.83-45_83-44dup,\N,\N,1/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
507054,21:45987940:G>T,NM_144991.2:c.83-51C>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.892,0.000166113,EXAC_EAS_AF,TSPEAR
507055,21:45987965:G>C,NM_144991.2:c.83-76C>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.779,\N,\N,TSPEAR
507056,21:45988085:C>G,NM_144991.2:c.83-196G>C,\N,\N,1/11,Unknown significance,\N,intron_variant,1.129,0.0008,1KG_AFR_AF,TSPEAR
507057,21:45988090:C>A,NM_144991.2:c.83-201G>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.262,0.001,1KG_SAS_AF,TSPEAR
507058,21:45988143:T>C,NM_144991.2:c.83-254A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,1.468,\N,\N,TSPEAR
507059,21:45988190:G>A,NM_144991.2:c.83-301C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,5.425,\N,\N,TSPEAR
507060,21:45988212:C>T,NM_144991.2:c.83-323G>A,\N,\N,1/11,Benign,\N,intron_variant,1.315,0.0408,1KG_AFR_AF,TSPEAR
507061,21:45988213:G>A,NM_144991.2:c.83-324C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.726,0.001,1KG_EUR_AF|1KG_SAS_AF,TSPEAR
507062,21:45988225:G>A,NM_144991.2:c.83-336C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.108,\N,\N,TSPEAR
507063,21:45988234:C>T,NM_144991.2:c.83-345G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,2.653,\N,\N,TSPEAR
507064,21:45988238:G>A,NM_144991.2:c.83-349C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,2.497,0.001,1KG_SAS_AF,TSPEAR
507065,21:45988253:C>A,NM_144991.2:c.83-364G>T,\N,\N,1/11,Benign,\N,intron_variant,4.171,0.0091,1KG_AFR_AF,TSPEAR
507066,21:45988273:G>A,NM_144991.2:c.83-384C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.296,0.0014,1KG_AMR_AF,TSPEAR
507067,21:45988287:C>A,NM_144991.2:c.83-398G>T,\N,\N,1/11,Benign,\N,intron_variant,2.254,0.006,1KG_EUR_AF,TSPEAR
507068,21:45988335:C>T,NM_144991.2:c.83-446G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,4.302,\N,\N,TSPEAR
507069,21:45988342:C>T,NM_144991.2:c.83-453G>A,\N,\N,1/11,Benign,\N,intron_variant,0.161,0.8413,1KG_EAS_AF,TSPEAR
507070,21:45988376:T>TG,NM_144991.2:c.83-488dup,\N,\N,1/11,Benign,\N,intron_variant,2.583,1,1KG_ALL_AF|1KG_AFR_AF|1KG_AMR_AF|1KG_EAS_AF|1KG_EUR_AF|1KG_SAS_AF,TSPEAR
507071,21:45988392:C>T,NM_144991.2:c.83-503G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,2.299,\N,\N,TSPEAR
507072,21:45988397:C>T,NM_144991.2:c.83-508G>A,\N,\N,1/11,Benign,\N,intron_variant,4.105,0.0219,1KG_AFR_AF,TSPEAR
507073,21:45988426:G>T,NM_144991.2:c.83-537C>A,\N,\N,1/11,Benign,\N,intron_variant,1.393,0.3929,1KG_EAS_AF,TSPEAR
507074,21:45988430:C>T,NM_144991.2:c.83-541G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,6.041,\N,\N,TSPEAR
507075,21:45988455:G>A,NM_144991.2:c.83-566C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.134,\N,\N,TSPEAR
507076,21:45988525:T>C,NM_144991.2:c.83-636A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.026,0.001,1KG_EAS_AF,TSPEAR
507077,21:45988536:C>T,NM_144991.2:c.83-647G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.463,\N,\N,TSPEAR
507078,21:45988552:C>A,NM_144991.2:c.83-663G>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.451,0.0008,1KG_AFR_AF,TSPEAR
507079,21:45988559:C>T,NM_144991.2:c.83-670G>A,\N,\N,1/11,Benign,\N,intron_variant,2.913,0.2371,1KG_EAS_AF,TSPEAR
507080,21:45988580:A>G,NM_144991.2:c.83-691T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,3.095,0.004,1KG_EUR_AF,TSPEAR
507081,21:45988611:C>CT,NM_144991.2:c.83-723dup,\N,\N,1/11,Benign,\N,intron_variant,4.676,0.0401,1KG_AFR_AF,TSPEAR
507082,21:45988649:G>T,NM_144991.2:c.83-760C>A,\N,\N,1/11,Unknown significance,\N,intron_variant,2.714,0.001,1KG_EAS_AF,TSPEAR
507083,21:45988669:G>A,NM_144991.2:c.83-780C>T,\N,\N,1/11,Benign,\N,intron_variant,0.53,0.0318,1KG_AFR_AF,TSPEAR
507084,21:45988691:C>G,NM_144991.2:c.83-802G>C,\N,\N,1/11,Unknown significance,\N,intron_variant,1.404,0.001,1KG_EAS_AF,TSPEAR
507085,21:45988710:A>G,NM_144991.2:c.83-821T>C,\N,\N,1/11,Benign,\N,intron_variant,1.733,0.2431,1KG_EAS_AF,TSPEAR
507086,21:45988735:C>T,NM_144991.2:c.83-846G>A,\N,\N,1/11,Benign,\N,intron_variant,1.371,0.006,1KG_EUR_AF,TSPEAR
507087,21:45988749:G>T,NM_144991.2:c.83-860C>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.651,\N,\N,TSPEAR
507088,21:45988778:G>A,NM_144991.2:c.83-889C>T,\N,\N,1/11,Benign,\N,intron_variant,2.848,0.013,1KG_AMR_AF,TSPEAR
507089,21:45988794:A>G,NM_144991.2:c.83-905T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,0.381,\N,\N,TSPEAR
507090,21:45988799:C>G,NM_144991.2:c.83-910G>C,\N,\N,1/11,Unknown significance,\N,intron_variant,1.151,\N,\N,TSPEAR
507091,21:45988820:C>T,NM_144991.2:c.83-931G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.434,0.001,1KG_SAS_AF,TSPEAR
507092,21:45988844:G>T,NM_144991.2:c.83-955C>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.849,\N,\N,TSPEAR
507093,21:45988856:A>C,NM_144991.2:c.83-967T>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.306,0.0008,1KG_AFR_AF,TSPEAR
507094,21:45988862:C>G,NM_144991.2:c.83-973G>C,\N,\N,1/11,Unknown significance,\N,intron_variant,1.038,\N,\N,TSPEAR
507095,21:45988863:G>A,NM_144991.2:c.83-974C>T,\N,\N,1/11,Benign,\N,intron_variant,2.482,0.0174,1KG_AFR_AF,TSPEAR
507096,21:45988888:A>T,NM_144991.2:c.83-999T>A,\N,\N,1/11,Unknown significance,\N,intron_variant,1.679,0.001,1KG_EAS_AF,TSPEAR
507097,21:45988906:C>T,NM_144991.2:c.83-1017G>A,\N,\N,1/11,Benign,\N,intron_variant,0.247,0.4067,1KG_EAS_AF,TSPEAR
507098,21:45988907:C>G,NM_144991.2:c.83-1018G>C,\N,\N,1/11,Unknown significance,\N,intron_variant,1.075,\N,\N,TSPEAR
507099,21:45988907:C>T,NM_144991.2:c.83-1018G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,3.012,0.0014,1KG_AMR_AF,TSPEAR
507100,21:45988908:G>A,NM_144991.2:c.83-1019C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.037,0.001,1KG_EUR_AF,TSPEAR
507101,21:45988919:C>T,NM_144991.2:c.83-1030G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,1.214,0.002,1KG_SAS_AF,TSPEAR
507102,21:45988920:G>A,NM_144991.2:c.83-1031C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.925,\N,\N,TSPEAR
507103,21:45988921:T>A,NM_144991.2:c.83-1032A>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.598,\N,\N,TSPEAR
507104,21:45988985:C>G,NM_144991.2:c.83-1096G>C,\N,\N,1/11,Unknown significance,\N,intron_variant,3.792,\N,\N,TSPEAR
507105,21:45988994:A>C,NM_144991.2:c.83-1105T>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.07,\N,\N,TSPEAR
507106,21:45988997:G>A,NM_144991.2:c.83-1108C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.262,0.001,1KG_EAS_AF,TSPEAR
507107,21:45989002:G>A,NM_144991.2:c.83-1113C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,4.311,0.0008,1KG_AFR_AF,TSPEAR
507108,21:45989008:C>T,NM_144991.2:c.83-1119G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.399,0.0008,1KG_AFR_AF,TSPEAR
507109,21:45989026:G>A,NM_144991.2:c.83-1137C>T,\N,\N,1/11,Benign,\N,intron_variant,1.915,0.0635,1KG_AFR_AF,TSPEAR
507110,21:45989035:G>C,NM_144991.2:c.83-1146C>G,\N,\N,1/11,Benign,\N,intron_variant,0.351,0.2381,1KG_EAS_AF,TSPEAR
507111,21:45989081:G>A,NM_144991.2:c.83-1192C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,2.367,0.0008,1KG_AFR_AF,TSPEAR
507112,21:45989095:C>G,NM_144991.2:c.83-1206G>C,\N,\N,1/11,Unknown significance,\N,intron_variant,2.308,0.0008,1KG_AFR_AF,TSPEAR
507113,21:45989115:C>T,NM_144991.2:c.83-1226G>A,\N,\N,1/11,Benign,\N,intron_variant,2.944,0.2282,1KG_EAS_AF,TSPEAR
507114,21:45989120:C>T,NM_144991.2:c.83-1231G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.042,0.0008,1KG_AFR_AF,TSPEAR
507115,21:45989127:G>A,NM_144991.2:c.83-1238C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.468,0.0008,1KG_AFR_AF,TSPEAR
507116,21:45989127:GC>AT,NM_144991.2:c.83-1239_83-1238delinsAT,\N,\N,1/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
507117,21:45989128:C>T,NM_144991.2:c.83-1239G>A,\N,\N,1/11,Benign,\N,intron_variant,1.034,0.4067,1KG_EAS_AF,TSPEAR
507118,21:45989134:C>G,NM_144991.2:c.83-1245G>C,\N,\N,1/11,Unknown significance,\N,intron_variant,3.811,\N,\N,TSPEAR
507119,21:45989146:C>T,NM_144991.2:c.83-1257G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,7.272,0.001,1KG_SAS_AF,TSPEAR
507120,21:45989149:A>C,NM_144991.2:c.83-1260T>G,\N,\N,1/11,Benign,\N,intron_variant,1.292,0.0159,1KG_EAS_AF,TSPEAR
507121,21:45989158:C>T,NM_144991.2:c.83-1269G>A,\N,\N,1/11,Benign,\N,intron_variant,2.586,0.0821,1KG_AMR_AF,TSPEAR
507122,21:45989159:G>A,NM_144991.2:c.83-1270C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,5.072,0.001,1KG_EAS_AF,TSPEAR
507123,21:45989170:T>G,NM_144991.2:c.83-1281A>C,\N,\N,1/11,Unknown significance,\N,intron_variant,1.931,0.0008,1KG_AFR_AF,TSPEAR
507124,21:45989183:G>A,NM_144991.2:c.83-1294C>T,\N,\N,1/11,Benign,\N,intron_variant,7.676,0.0144,1KG_AFR_AF,TSPEAR
507125,21:45989191:C>T,NM_144991.2:c.83-1302G>A,\N,\N,1/11,Benign,\N,intron_variant,6.482,0.2381,1KG_EAS_AF,TSPEAR
507126,21:45989197:C>T,NM_144991.2:c.83-1308G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,5.697,\N,\N,TSPEAR
507127,21:45989204:G>T,NM_144991.2:c.83-1315C>A,\N,\N,1/11,Unknown significance,\N,intron_variant,1.637,\N,\N,TSPEAR
507128,21:45989207:C>T,NM_144991.2:c.83-1318G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,5.612,0.0015,1KG_AFR_AF,TSPEAR
507129,21:45989211:C>A,NM_144991.2:c.83-1322G>T,\N,\N,1/11,Benign,\N,intron_variant,9.967,0.2391,1KG_EAS_AF,TSPEAR
507130,21:45989216:G>A,NM_144991.2:c.83-1327C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,2.084,\N,\N,TSPEAR
507131,21:45989235:C>A,NM_144991.2:c.83-1346G>T,\N,\N,1/11,Benign,\N,intron_variant,3.634,0.0144,1KG_AFR_AF,TSPEAR
507132,21:45989255:G>A,NM_144991.2:c.83-1366C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.543,0.001,1KG_SAS_AF,TSPEAR
507133,21:45989257:C>T,NM_144991.2:c.83-1368G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,6.676,\N,\N,TSPEAR
507134,21:45989264:G>A,NM_144991.2:c.83-1375C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,6.089,0.002,1KG_SAS_AF,TSPEAR
507135,21:45989270:TGCAGGAACAGCCGGCAAA>T,NM_144991.2:c.83-1399_83-1382del,\N,\N,1/11,Unknown significance,\N,intron_variant,\N,0.003,1KG_AFR_AF,TSPEAR
507136,21:45989277:A>G,NM_144991.2:c.83-1388T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,5.53,\N,\N,TSPEAR
507137,21:45989282:C>T,NM_144991.2:c.83-1393G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,7.607,0.0014,1KG_AMR_AF,TSPEAR
507138,21:45989283:G>A,NM_144991.2:c.83-1394C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,6.571,0.0008,1KG_AFR_AF,TSPEAR
507139,21:45989295:G>A,NM_144991.2:c.83-1406C>T,\N,\N,1/11,Benign,\N,intron_variant,1.118,0.0348,1KG_AFR_AF,TSPEAR
507140,21:45989300:C>T,NM_144991.2:c.83-1411G>A,\N,\N,1/11,Benign,\N,intron_variant,3.3,0.0072,1KG_SAS_AF,TSPEAR
507141,21:45989311:C>T,NM_144991.2:c.83-1422G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,2.194,0.0008,1KG_AFR_AF,TSPEAR
507142,21:45989415:GGT>G,NM_144991.2:c.83-1528_83-1527del,\N,\N,1/11,Unknown significance,\N,intron_variant,1.153,\N,\N,TSPEAR
507143,21:45989434:C>T,NM_144991.2:c.83-1545G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,1.657,0.0008,1KG_AFR_AF,TSPEAR
507144,21:45989439:C>A,NM_144991.2:c.83-1550G>T,\N,\N,1/11,Unknown significance,\N,intron_variant,6.669,0.004,1KG_EAS_AF,TSPEAR
507145,21:45989461:C>A,NM_144991.2:c.83-1572G>T,\N,\N,1/11,Unknown significance,\N,intron_variant,5.029,0.0031,1KG_SAS_AF,TSPEAR
507146,21:45989469:G>A,NM_144991.2:c.83-1580C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,2.1,0.0014,1KG_AMR_AF,TSPEAR
507147,21:45989488:G>T,NM_144991.2:c.83-1599C>A,\N,\N,1/11,Benign,\N,intron_variant,1.245,0.8383,1KG_EAS_AF,TSPEAR
507148,21:45989489:G>C,NM_144991.2:c.83-1600C>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.711,0.001,1KG_EAS_AF,TSPEAR
507149,21:45989491:G>A,NM_144991.2:c.83-1602C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.206,0.001,1KG_SAS_AF,TSPEAR
507150,21:45989493:C>G,NM_144991.2:c.83-1604G>C,\N,\N,1/11,Unknown significance,\N,intron_variant,3.798,0.0014,1KG_AMR_AF,TSPEAR
507151,21:45989501:AG>A,NM_144991.2:c.83-1613del,\N,\N,1/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
507152,21:45989507:G>A,NM_144991.2:c.83-1618C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,7.012,0.001,1KG_EUR_AF,TSPEAR
507153,21:45989510:G>T,NM_144991.2:c.83-1621C>A,\N,\N,1/11,Unknown significance,\N,intron_variant,2.035,0.001,1KG_SAS_AF,TSPEAR
507154,21:45989553:G>C,NM_144991.2:c.83-1664C>G,\N,\N,1/11,Unknown significance,\N,intron_variant,3.383,\N,\N,TSPEAR
507155,21:45989561:G>A,NM_144991.2:c.83-1672C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,7.511,0.002,1KG_EAS_AF,TSPEAR
507156,21:45989570:C>A,NM_144991.2:c.83-1681G>T,\N,\N,1/11,Benign,\N,intron_variant,8.885,0.0499,1KG_AFR_AF,TSPEAR
507157,21:45989570:C>G,NM_144991.2:c.83-1681G>C,\N,\N,1/11,Benign,\N,intron_variant,7.886,0.0545,1KG_AFR_AF,TSPEAR
507158,21:45989572:T>G,NM_144991.2:c.83-1683A>C,\N,\N,1/11,Unknown significance,\N,intron_variant,6.548,0.0008,1KG_AFR_AF,TSPEAR
507159,21:45989576:C>T,NM_144991.2:c.83-1687G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,6.679,0.001,1KG_EAS_AF,TSPEAR
507160,21:45989577:G>A,NM_144991.2:c.83-1688C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,2.657,\N,\N,TSPEAR
507161,21:45989646:T>C,NM_144991.2:c.83-1757A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,2.921,0.0023,1KG_AFR_AF,TSPEAR
507162,21:45989654:T>A,NM_144991.2:c.83-1765A>T,\N,\N,1/11,Unknown significance,\N,intron_variant,6.041,\N,\N,TSPEAR
507163,21:45989676:G>A,NM_144991.2:c.83-1787C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.278,\N,\N,TSPEAR
507164,21:45989687:C>T,NM_144991.2:c.83-1798G>A,\N,\N,1/11,Benign,\N,intron_variant,4.976,0.0102,1KG_SAS_AF,TSPEAR
507165,21:45989714:G>A,NM_144991.2:c.83-1825C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,11.48,0.001,1KG_EUR_AF,TSPEAR
507166,21:45989762:A>C,NM_144991.2:c.83-1873T>G,\N,\N,1/11,Unknown significance,\N,intron_variant,8.436,0.0015,1KG_AFR_AF,TSPEAR
507167,21:45989775:T>C,NM_144991.2:c.83-1886A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,4.261,0.0014,1KG_AMR_AF,TSPEAR
507168,21:45989795:C>T,NM_144991.2:c.83-1906G>A,\N,\N,1/11,Benign,\N,intron_variant,2.16,0.0371,1KG_AFR_AF,TSPEAR
507169,21:45989796:G>A,NM_144991.2:c.83-1907C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.192,0.003,1KG_AFR_AF,TSPEAR
507170,21:45989801:T>C,NM_144991.2:c.83-1912A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,1.225,\N,\N,TSPEAR
507171,21:45989815:C>T,NM_144991.2:c.83-1926G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,7.605,0.0031,1KG_SAS_AF,TSPEAR
507172,21:45989828:C>T,NM_144991.2:c.83-1939G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,2.983,\N,\N,TSPEAR
507173,21:45989834:G>A,NM_144991.2:c.83-1945C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.286,0.0008,1KG_AFR_AF,TSPEAR
507174,21:45989873:C>G,NM_144991.2:c.83-1984G>C,\N,\N,1/11,Unknown significance,\N,intron_variant,3.414,0.0008,1KG_AFR_AF,TSPEAR
507175,21:45989873:C>T,NM_144991.2:c.83-1984G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,4.208,\N,\N,TSPEAR
507176,21:45989881:C>T,NM_144991.2:c.83-1992G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,5.312,\N,\N,TSPEAR
507177,21:45989887:T>G,NM_144991.2:c.83-1998A>C,\N,\N,1/11,Unknown significance,\N,intron_variant,0.104,0.0014,1KG_AMR_AF,TSPEAR
507178,21:45989897:C>T,NM_144991.2:c.83-2008G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,6.59,\N,\N,TSPEAR
507179,21:45989907:G>A,NM_144991.2:c.83-2018C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,6.65,0.0008,1KG_AFR_AF,TSPEAR
507180,21:45989913:C>A,NM_144991.2:c.83-2024G>T,\N,\N,1/11,Unknown significance,\N,intron_variant,5.299,0.0014,1KG_AMR_AF,TSPEAR
507181,21:45989919:T>C,NM_144991.2:c.83-2030A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,1.863,0.001,1KG_EUR_AF,TSPEAR
507182,21:45989970:C>T,NM_144991.2:c.83-2081G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,3.849,\N,\N,TSPEAR
507183,21:45989971:G>A,NM_144991.2:c.83-2082C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.434,0.0015,1KG_AFR_AF,TSPEAR
507184,21:45989976:G>A,NM_144991.2:c.83-2087C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,4.067,0.001,1KG_EUR_AF,TSPEAR
507185,21:45989997:A>G,NM_144991.2:c.83-2108T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,1.011,0.0008,1KG_AFR_AF,TSPEAR
507186,21:45990004:G>A,NM_144991.2:c.83-2115C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.292,\N,\N,TSPEAR
507187,21:45990033:A>G,NM_144991.2:c.83-2144T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,0.033,\N,\N,TSPEAR
507188,21:45990047:G>A,NM_144991.2:c.83-2158C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,9.617,\N,\N,TSPEAR
507189,21:45990068:G>A,NM_144991.2:c.83-2179C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.889,0.0023,1KG_AFR_AF,TSPEAR
507190,21:45990086:A>G,NM_144991.2:c.83-2197T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,4.554,0.0008,1KG_AFR_AF,TSPEAR
507191,21:45990088:C>T,NM_144991.2:c.83-2199G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.291,0.0023,1KG_AFR_AF,TSPEAR
507192,21:45990092:C>T,NM_144991.2:c.83-2203G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,5.719,\N,\N,TSPEAR
507193,21:45990097:G>T,NM_144991.2:c.83-2208C>A,\N,\N,1/11,Unknown significance,\N,intron_variant,4.613,\N,\N,TSPEAR
507194,21:45990162:T>C,NM_144991.2:c.83-2273A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,2.964,0.001,1KG_EUR_AF,TSPEAR
507195,21:45990171:C>T,NM_144991.2:c.83-2282G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,6.34,\N,\N,TSPEAR
507196,21:45990177:C>T,NM_144991.2:c.83-2288G>A,\N,\N,1/11,Benign,\N,intron_variant,9.302,0.0072,1KG_AMR_AF,TSPEAR
507197,21:45990185:C>T,NM_144991.2:c.83-2296G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,3.976,0.0008,1KG_AFR_AF,TSPEAR
507198,21:45990186:G>A,NM_144991.2:c.83-2297C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.029,0.001,1KG_EAS_AF,TSPEAR
507199,21:45990196:C>A,NM_144991.2:c.83-2307G>T,\N,\N,1/11,Unknown significance,\N,intron_variant,4.22,0.001,1KG_EAS_AF,TSPEAR
507200,21:45990238:C>T,NM_144991.2:c.83-2349G>A,\N,\N,1/11,Benign,\N,intron_variant,5.999,0.0091,1KG_AFR_AF,TSPEAR
507201,21:45990257:T>C,NM_144991.2:c.83-2368A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,1.994,\N,\N,TSPEAR
507202,21:45990264:G>A,NM_144991.2:c.83-2375C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.713,\N,\N,TSPEAR
507203,21:45990268:C>T,NM_144991.2:c.83-2379G>A,\N,\N,1/11,Benign,\N,intron_variant,4.016,0.0318,1KG_AFR_AF,TSPEAR
507204,21:45990334:C>T,NM_144991.2:c.83-2445G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,3.551,\N,\N,TSPEAR
507205,21:45990349:G>A,NM_144991.2:c.83-2460C>T,\N,\N,1/11,Benign,\N,intron_variant,0.02,0.0098,1KG_AFR_AF,TSPEAR
507206,21:45990349:G>T,NM_144991.2:c.83-2460C>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.008,\N,\N,TSPEAR
507207,21:45990374:G>A,NM_144991.2:c.83-2485C>T,\N,\N,1/11,Benign,\N,intron_variant,3.349,0.005,1KG_EUR_AF,TSPEAR
507208,21:45990380:T>C,NM_144991.2:c.83-2491A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.265,\N,\N,TSPEAR
507209,21:45990402:G>C,NM_144991.2:c.83-2513C>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.398,0.003,1KG_EUR_AF,TSPEAR
507210,21:45990412:C>T,NM_144991.2:c.83-2523G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,4.389,0.0008,1KG_AFR_AF,TSPEAR
507211,21:45990422:C>T,NM_144991.2:c.83-2533G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,4.564,\N,\N,TSPEAR
507212,21:45990445:C>T,NM_144991.2:c.83-2556G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,3.057,0.001,1KG_SAS_AF,TSPEAR
507213,21:45990446:G>A,NM_144991.2:c.83-2557C>T,\N,\N,1/11,Benign,\N,intron_variant,0.739,0.8403,1KG_EAS_AF,TSPEAR
507214,21:45990458:G>T,NM_144991.2:c.83-2569C>A,\N,\N,1/11,Benign,\N,intron_variant,1.437,0.0068,1KG_AFR_AF,TSPEAR
507215,21:45990470:C>T,NM_144991.2:c.83-2581G>A,\N,\N,1/11,Benign,\N,intron_variant,2.884,0.0368,1KG_EUR_AF,TSPEAR
507216,21:45990471:G>A,NM_144991.2:c.83-2582C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.979,\N,\N,TSPEAR
507217,21:45990474:C>T,NM_144991.2:c.83-2585G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.564,\N,\N,TSPEAR
507218,21:45990475:G>A,NM_144991.2:c.83-2586C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.354,\N,\N,TSPEAR
507219,21:45990485:A>C,NM_144991.2:c.83-2596T>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.527,\N,\N,TSPEAR
507220,21:45990522:C>T,NM_144991.2:c.83-2633G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,3.615,0.001,1KG_EAS_AF,TSPEAR
507221,21:45990535:G>C,NM_144991.2:c.83-2646C>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.891,\N,\N,TSPEAR
507222,21:45990575:A>G,NM_144991.2:c.83-2686T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,2.023,\N,\N,TSPEAR
507223,21:45990576:G>C,NM_144991.2:c.83-2687C>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.287,0.0008,1KG_AFR_AF,TSPEAR
507224,21:45990580:G>A,NM_144991.2:c.83-2691C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.112,0.0014,1KG_AMR_AF,TSPEAR
507225,21:45990636:C>T,NM_144991.2:c.83-2747G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,5.375,0.0008,1KG_AFR_AF,TSPEAR
507226,21:45990639:A>C,NM_144991.2:c.83-2750T>G,\N,\N,1/11,Unknown significance,\N,intron_variant,4.147,0.0023,1KG_AFR_AF,TSPEAR
507227,21:45990665:T>G,NM_144991.2:c.83-2776A>C,\N,\N,1/11,Unknown significance,\N,intron_variant,1.428,0.0008,1KG_AFR_AF,TSPEAR
507228,21:45990707:T>C,NM_144991.2:c.83-2818A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,1.262,\N,\N,TSPEAR
507229,21:45990718:T>G,NM_144991.2:c.83-2829A>C,\N,\N,1/11,Unknown significance,\N,intron_variant,5.717,\N,\N,TSPEAR
507230,21:45990732:G>C,NM_144991.2:c.83-2843C>G,\N,\N,1/11,Unknown significance,\N,intron_variant,1.392,0.0014,1KG_AMR_AF,TSPEAR
507231,21:45990749:C>T,NM_144991.2:c.83-2860G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.192,\N,\N,TSPEAR
507232,21:45990755:G>A,NM_144991.2:c.83-2866C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,2.438,0.0045,1KG_AFR_AF,TSPEAR
507233,21:45990765:T>C,NM_144991.2:c.83-2876A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,1.516,0.001,1KG_SAS_AF,TSPEAR
507234,21:45990784:G>A,NM_144991.2:c.83-2895C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,2.562,0,1KG_ALL_AF|1KG_AFR_AF|1KG_AMR_AF|1KG_EAS_AF|1KG_EUR_AF|1KG_SAS_AF,TSPEAR
507235,21:45990791:T>C,NM_144991.2:c.83-2902A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.871,0.001,1KG_EAS_AF,TSPEAR
507236,21:45990793:C>T,NM_144991.2:c.83-2904G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,4.002,\N,\N,TSPEAR
507237,21:45990804:G>A,NM_144991.2:c.83-2915C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.109,\N,\N,TSPEAR
507238,21:45990819:T>C,NM_144991.2:c.83-2930A>G,\N,\N,1/11,Benign,\N,intron_variant,1.753,0.2495,1KG_EUR_AF,TSPEAR
507239,21:45990839:T>G,NM_144991.2:c.83-2950A>C,\N,\N,1/11,Unknown significance,\N,intron_variant,0.915,0.002,1KG_EUR_AF,TSPEAR
507240,21:45990840:T>TG,NM_144991.2:c.83-2952dup,\N,\N,1/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
507241,21:45990848:C>T,NM_144991.2:c.83-2959G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,3.528,\N,\N,TSPEAR
507242,21:45990852:T>C,NM_144991.2:c.83-2963A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,2.116,0.002,1KG_EUR_AF,TSPEAR
507243,21:45990892:T>C,NM_144991.2:c.83-3003A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,1.595,\N,\N,TSPEAR
507244,21:45990898:G>A,NM_144991.2:c.83-3009C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.452,\N,\N,TSPEAR
507245,21:45990907:T>A,NM_144991.2:c.83-3018A>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.958,\N,\N,TSPEAR
507246,21:45990928:A>G,NM_144991.2:c.83-3039T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,0.528,0.0008,1KG_AFR_AF,TSPEAR
507247,21:45991015:G>A,NM_144991.2:c.83-3126C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,4.836,0.001,1KG_EAS_AF,TSPEAR
507248,21:45991026:G>A,NM_144991.2:c.83-3137C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.039,0.0008,1KG_AFR_AF,TSPEAR
507249,21:45991038:A>G,NM_144991.2:c.83-3149T>C,\N,\N,1/11,Benign,\N,intron_variant,1.248,0.4067,1KG_EAS_AF,TSPEAR
507250,21:45991045:G>A,NM_144991.2:c.83-3156C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,2.271,\N,\N,TSPEAR
507251,21:45991110:C>T,NM_144991.2:c.83-3221G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.922,\N,\N,TSPEAR
507252,21:45991124:G>T,NM_144991.2:c.83-3235C>A,\N,\N,1/11,Unknown significance,\N,intron_variant,2.37,\N,\N,TSPEAR
507253,21:45991146:T>A,NM_144991.2:c.83-3257A>T,\N,\N,1/11,Unknown significance,\N,intron_variant,11.76,0.001,1KG_EAS_AF,TSPEAR
507254,21:45991165:T>G,NM_144991.2:c.83-3276A>C,\N,\N,1/11,Unknown significance,\N,intron_variant,8.632,0.0045,1KG_AFR_AF,TSPEAR
507255,21:45991174:C>G,NM_144991.2:c.83-3285G>C,\N,\N,1/11,Unknown significance,\N,intron_variant,11.87,0.0014,1KG_AMR_AF,TSPEAR
507256,21:45991174:C>T,NM_144991.2:c.83-3285G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,12.23,\N,\N,TSPEAR
507257,21:45991196:G>A,NM_144991.2:c.83-3307C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,10.73,0.001,1KG_EAS_AF,TSPEAR
507258,21:45991262:C>T,NM_144991.2:c.83-3373G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,3.934,0.001,1KG_EUR_AF,TSPEAR
507259,21:45991288:G>A,NM_144991.2:c.83-3399C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.327,\N,\N,TSPEAR
507260,21:45991288:G>C,NM_144991.2:c.83-3399C>G,\N,\N,1/11,Benign,\N,intron_variant,0.272,0.6438,1KG_EAS_AF,TSPEAR
507261,21:45991302:G>A,NM_144991.2:c.83-3413C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.77,0.004,1KG_EUR_AF,TSPEAR
507262,21:45991328:G>A,NM_144991.2:c.83-3439C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.831,0.003,1KG_AFR_AF,TSPEAR
507263,21:45991364:C>T,NM_144991.2:c.83-3475G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.799,0.001,1KG_EUR_AF,TSPEAR
507264,21:45991377:G>A,NM_144991.2:c.83-3488C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,4.218,\N,\N,TSPEAR
507265,21:45991389:T>C,NM_144991.2:c.83-3500A>G,\N,\N,1/11,Benign,\N,intron_variant,1.773,0.6617,1KG_EAS_AF,TSPEAR
507266,21:45991439:C>T,NM_144991.2:c.83-3550G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.81,\N,\N,TSPEAR
507267,21:45991440:G>A,NM_144991.2:c.83-3551C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.284,0.001,1KG_EUR_AF,TSPEAR
507268,21:45991475:G>A,NM_144991.2:c.83-3586C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.862,0.003,1KG_AFR_AF,TSPEAR
507269,21:45991517:T>G,NM_144991.2:c.83-3628A>C,\N,\N,1/11,Unknown significance,\N,intron_variant,0.31,0.003,1KG_EUR_AF,TSPEAR
507270,21:45991529:T>G,NM_144991.2:c.83-3640A>C,\N,\N,1/11,Unknown significance,\N,intron_variant,6.245,0.0008,1KG_AFR_AF,TSPEAR
507271,21:45991537:G>A,NM_144991.2:c.83-3648C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,8.687,0.0008,1KG_AFR_AF,TSPEAR
507272,21:45991578:A>T,NM_144991.2:c.83-3689T>A,\N,\N,1/11,Unknown significance,\N,intron_variant,1.262,0.001,1KG_EUR_AF,TSPEAR
507273,21:45991579:C>T,NM_144991.2:c.83-3690G>A,\N,\N,1/11,Benign,\N,intron_variant,0.494,0.0053,1KG_AFR_AF,TSPEAR
507274,21:45991580:G>C,NM_144991.2:c.83-3691C>G,\N,\N,1/11,Benign,\N,intron_variant,0.671,0.0446,1KG_AFR_AF,TSPEAR
507275,21:45991584:G>C,NM_144991.2:c.83-3695C>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.467,0.001,1KG_EAS_AF,TSPEAR
507276,21:45991585:G>A,NM_144991.2:c.83-3696C>T,\N,\N,1/11,Benign,\N,intron_variant,2.572,0.0446,1KG_AFR_AF,TSPEAR
507277,21:45991628:T>C,NM_144991.2:c.83-3739A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.11,0.001,1KG_EAS_AF,TSPEAR
507278,21:45991630:G>A,NM_144991.2:c.83-3741C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.644,\N,\N,TSPEAR
507279,21:45991661:G>T,NM_144991.2:c.83-3772C>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.237,\N,\N,TSPEAR
507280,21:45991709:T>G,NM_144991.2:c.83-3820A>C,\N,\N,1/11,Benign,\N,intron_variant,2.168,0.0129,1KG_AFR_AF,TSPEAR
507281,21:45991744:G>A,NM_144991.2:c.83-3855C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,4.852,\N,\N,TSPEAR
507282,21:45991764:G>A,NM_144991.2:c.83-3875C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,7.276,0.0023,1KG_AFR_AF,TSPEAR
507283,21:45991799:A>G,NM_144991.2:c.83-3910T>C,\N,\N,1/11,Benign,\N,intron_variant,12.41,0.2495,1KG_EUR_AF,TSPEAR
507284,21:45991817:C>T,NM_144991.2:c.83-3928G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,3.298,0.0008,1KG_AFR_AF,TSPEAR
507285,21:45991822:G>A,NM_144991.2:c.83-3933C>T,\N,\N,1/11,Benign,\N,intron_variant,0.449,0.0227,1KG_AFR_AF,TSPEAR
507286,21:45991825:C>T,NM_144991.2:c.83-3936G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,1.923,0.0014,1KG_AMR_AF,TSPEAR
507287,21:45991826:G>C,NM_144991.2:c.83-3937C>G,\N,\N,1/11,Benign,\N,intron_variant,0.622,0.1029,1KG_AFR_AF,TSPEAR
507288,21:45991835:G>A,NM_144991.2:c.83-3946C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.428,0.003,1KG_AFR_AF,TSPEAR
507289,21:45991844:C>T,NM_144991.2:c.83-3955G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,4.193,0.001,1KG_EUR_AF,TSPEAR
507290,21:45991845:CA>C,NM_144991.2:c.83-3957del,\N,\N,1/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
507291,21:45991854:C>T,NM_144991.2:c.83-3965G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,2.716,0.0014,1KG_AMR_AF,TSPEAR
507292,21:45991863:G>A,NM_144991.2:c.83-3974C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.242,\N,\N,TSPEAR
507293,21:45991874:C>T,NM_144991.2:c.83-3985G>A,\N,\N,1/11,Benign,\N,intron_variant,0.372,0.0061,1KG_SAS_AF,TSPEAR
507294,21:45991875:G>A,NM_144991.2:c.83-3986C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.371,\N,\N,TSPEAR
507295,21:45991877:G>A,NM_144991.2:c.83-3988C>T,\N,\N,1/11,Benign,\N,intron_variant,1.755,0.2391,1KG_EAS_AF,TSPEAR
507296,21:45991903:A>G,NM_144991.2:c.83-4014T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,5.365,0.001,1KG_SAS_AF,TSPEAR
507297,21:45991925:G>A,NM_144991.2:c.83-4036C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.514,0.003,1KG_EAS_AF,TSPEAR
507298,21:45991929:C>A,NM_144991.2:c.83-4040G>T,\N,\N,1/11,Benign,\N,intron_variant,4.53,0.2495,1KG_EUR_AF,TSPEAR
507299,21:45991931:G>A,NM_144991.2:c.83-4042C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.013,0.0015,1KG_AFR_AF,TSPEAR
507300,21:45991932:C>T,NM_144991.2:c.83-4043G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,4.214,\N,\N,TSPEAR
507301,21:45991933:G>A,NM_144991.2:c.83-4044C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.324,\N,\N,TSPEAR
507302,21:45991944:C>T,NM_144991.2:c.83-4055G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,2.607,0.0045,1KG_AFR_AF,TSPEAR
507303,21:45991945:G>A,NM_144991.2:c.83-4056C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,2.722,\N,\N,TSPEAR
507304,21:45991947:G>A,NM_144991.2:c.83-4058C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.786,0.002,1KG_EUR_AF,TSPEAR
507305,21:45991971:G>A,NM_144991.2:c.83-4082C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.142,0.0023,1KG_AFR_AF,TSPEAR
507306,21:45991975:A>G,NM_144991.2:c.83-4086T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,1.188,0.001,1KG_EUR_AF,TSPEAR
507307,21:45991989:A>T,NM_144991.2:c.83-4100T>A,\N,\N,1/11,Unknown significance,\N,intron_variant,6.739,0.001,1KG_SAS_AF,TSPEAR
507308,21:45992003:A>G,NM_144991.2:c.83-4114T>C,\N,\N,1/11,Benign,\N,intron_variant,0.835,0.8413,1KG_EAS_AF,TSPEAR
507309,21:45992003:ACG>GCA,NM_144991.2:c.83-4116_83-4114delinsTGC,\N,\N,1/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
507310,21:45992004:C>T,NM_144991.2:c.83-4115G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,3.597,\N,\N,TSPEAR
507311,21:45992005:G>A,NM_144991.2:c.83-4116C>T,\N,\N,1/11,Benign,\N,intron_variant,0.189,0.0174,1KG_AFR_AF,TSPEAR
507312,21:45992011:C>G,NM_144991.2:c.83-4122G>C,\N,\N,1/11,Unknown significance,\N,intron_variant,0.576,\N,\N,TSPEAR
507313,21:45992013:C>T,NM_144991.2:c.83-4124G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,3.273,0.001,1KG_EUR_AF,TSPEAR
507314,21:45992015:C>G,NM_144991.2:c.83-4126G>C,\N,\N,1/11,Unknown significance,\N,intron_variant,0.339,\N,\N,TSPEAR
507315,21:45992022:C>T,NM_144991.2:c.83-4133G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,3.109,\N,\N,TSPEAR
507316,21:45992045:C>T,NM_144991.2:c.83-4156G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,3.581,0.0031,1KG_SAS_AF,TSPEAR
507317,21:45992053:G>A,NM_144991.2:c.83-4164C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.317,0.001,1KG_EUR_AF,TSPEAR
507318,21:45992061:A>G,NM_144991.2:c.83-4172T>C,\N,\N,1/11,Benign,\N,intron_variant,0.797,0.1014,1KG_AFR_AF,TSPEAR
507319,21:45992070:C>T,NM_144991.2:c.83-4181G>A,\N,\N,1/11,Benign,\N,intron_variant,3.895,0.0308,1KG_EUR_AF,TSPEAR
507320,21:45992076:G>A,NM_144991.2:c.83-4187C>T,\N,\N,1/11,Benign,\N,intron_variant,3.93,0.2823,1KG_EUR_AF,TSPEAR
507321,21:45992090:A>C,NM_144991.2:c.83-4201T>G,\N,\N,1/11,Unknown significance,\N,intron_variant,1.12,\N,\N,TSPEAR
507322,21:45992114:G>A,NM_144991.2:c.83-4225C>T,\N,\N,1/11,Benign,\N,intron_variant,0.697,0.006,1KG_EAS_AF,TSPEAR
507323,21:45992131:C>T,NM_144991.2:c.83-4242G>A,\N,\N,1/11,Benign,\N,intron_variant,5.085,0.6448,1KG_EAS_AF,TSPEAR
507324,21:45992140:G>C,NM_144991.2:c.83-4251C>G,\N,\N,1/11,Benign,\N,intron_variant,1.168,0.6458,1KG_EAS_AF,TSPEAR
507325,21:45992152:C>A,NM_144991.2:c.83-4263G>T,\N,\N,1/11,Unknown significance,\N,intron_variant,2.905,0.0008,1KG_AFR_AF,TSPEAR
507326,21:45992181:C>T,NM_144991.2:c.83-4292G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,3.765,0.0008,1KG_AFR_AF,TSPEAR
507327,21:45992182:G>A,NM_144991.2:c.83-4293C>T,\N,\N,1/11,Benign,\N,intron_variant,4.045,0.2485,1KG_EUR_AF,TSPEAR
507328,21:45992187:T>G,NM_144991.2:c.83-4298A>C,\N,\N,1/11,Unknown significance,\N,intron_variant,0.259,\N,\N,TSPEAR
507329,21:45992197:T>G,NM_144991.2:c.83-4308A>C,\N,\N,1/11,Unknown significance,\N,intron_variant,0.459,0.001,1KG_EAS_AF,TSPEAR
507330,21:45992205:G>T,NM_144991.2:c.83-4316C>A,\N,\N,1/11,Unknown significance,\N,intron_variant,1.819,\N,\N,TSPEAR
507331,21:45992206:A>C,NM_144991.2:c.83-4317T>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.073,\N,\N,TSPEAR
507332,21:45992209:G>A,NM_144991.2:c.83-4320C>T,\N,\N,1/11,Benign,\N,intron_variant,0.279,0.0136,1KG_AFR_AF,TSPEAR
507333,21:45992217:T>A,NM_144991.2:c.83-4328A>T,\N,\N,1/11,Unknown significance,\N,intron_variant,7.38,\N,\N,TSPEAR
507334,21:45992231:G>C,NM_144991.2:c.83-4342C>G,\N,\N,1/11,Unknown significance,\N,intron_variant,1.115,0.0015,1KG_AFR_AF,TSPEAR
507335,21:45992231:G>T,NM_144991.2:c.83-4342C>A,\N,\N,1/11,Benign,\N,intron_variant,2.204,0.0492,1KG_AFR_AF,TSPEAR
507336,21:45992235:C>T,NM_144991.2:c.83-4346G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.114,\N,\N,TSPEAR
507337,21:45992236:G>A,NM_144991.2:c.83-4347C>T,\N,\N,1/11,Benign,\N,intron_variant,1.544,0.2485,1KG_EUR_AF,TSPEAR
507338,21:45992260:G>A,NM_144991.2:c.83-4371C>T,\N,\N,1/11,Benign,\N,intron_variant,1.179,0.6448,1KG_EAS_AF,TSPEAR
507339,21:45992266:C>T,NM_144991.2:c.83-4377G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,4.533,\N,\N,TSPEAR
507340,21:45992267:G>A,NM_144991.2:c.83-4378C>T,\N,\N,1/11,Benign,\N,intron_variant,4.287,0.0492,1KG_AFR_AF,TSPEAR
507341,21:45992275:C>T,NM_144991.2:c.83-4386G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,3.4,0.001,1KG_EUR_AF,TSPEAR
507342,21:45992276:G>A,NM_144991.2:c.83-4387C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.25,0.0023,1KG_AFR_AF,TSPEAR
507343,21:45992286:C>T,NM_144991.2:c.83-4397G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,5.236,0.0038,1KG_AFR_AF,TSPEAR
507344,21:45992287:G>A,NM_144991.2:c.83-4398C>T,\N,\N,1/11,Benign,\N,intron_variant,4.27,0.8254,1KG_EAS_AF,TSPEAR
507345,21:45992290:G>A,NM_144991.2:c.83-4401C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.969,\N,\N,TSPEAR
507346,21:45992294:G>A,NM_144991.2:c.83-4405C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.066,0.001,1KG_SAS_AF,TSPEAR
507347,21:45992303:T>C,NM_144991.2:c.83-4414A>G,\N,\N,1/11,Benign,\N,intron_variant,2.316,0.8413,1KG_EAS_AF,TSPEAR
507348,21:45992305:C>T,NM_144991.2:c.83-4416G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.908,0.004,1KG_EAS_AF,TSPEAR
507349,21:45992367:G>C,NM_144991.2:c.83-4478C>G,\N,\N,1/11,Benign,\N,intron_variant,0.669,0.0076,1KG_AFR_AF,TSPEAR
507350,21:45992380:C>T,NM_144991.2:c.83-4491G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,1.689,\N,\N,TSPEAR
507351,21:45992390:G>A,NM_144991.2:c.83-4501C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,2.696,0.0014,1KG_AMR_AF,TSPEAR
507352,21:45992414:C>T,NM_144991.2:c.83-4525G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,1.239,0.001,1KG_SAS_AF,TSPEAR
507353,21:45992449:G>T,NM_144991.2:c.83-4560C>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.842,0.0014,1KG_AMR_AF,TSPEAR
507354,21:45992454:C>A,NM_144991.2:c.83-4565G>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.827,\N,\N,TSPEAR
507355,21:45992454:C>T,NM_144991.2:c.83-4565G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,1.874,\N,\N,TSPEAR
507356,21:45992455:G>A,NM_144991.2:c.83-4566C>T,\N,\N,1/11,Benign,\N,intron_variant,1.703,0.253,1KG_EAS_AF,TSPEAR
507357,21:45992470:C>T,NM_144991.2:c.83-4581G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,1.943,0.0015,1KG_AFR_AF,TSPEAR
507358,21:45992475:C>T,NM_144991.2:c.83-4586G>A,\N,\N,1/11,Benign,\N,intron_variant,3.463,0.8413,1KG_EAS_AF,TSPEAR
507359,21:45992489:C>T,NM_144991.2:c.83-4600G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,4.685,\N,\N,TSPEAR
507360,21:45992502:C>T,NM_144991.2:c.83-4613G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,1.23,\N,\N,TSPEAR
507361,21:45992560:G>A,NM_144991.2:c.83-4671C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,4.008,0.001,1KG_EUR_AF|1KG_SAS_AF,TSPEAR
507362,21:45992573:G>A,NM_144991.2:c.83-4684C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.247,0.0015,1KG_AFR_AF,TSPEAR
507363,21:45992579:G>A,NM_144991.2:c.83-4690C>T,\N,\N,1/11,Benign,\N,intron_variant,0.474,0.0809,1KG_AFR_AF,TSPEAR
507364,21:45992610:A>G,NM_144991.2:c.83-4721T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,7.023,0.0008,1KG_AFR_AF,TSPEAR
507365,21:45992613:C>T,NM_144991.2:c.83-4724G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,4.247,0.001,1KG_SAS_AF,TSPEAR
507366,21:45992615:A>G,NM_144991.2:c.83-4726T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,0.711,\N,\N,TSPEAR
507367,21:45992630:C>T,NM_144991.2:c.83-4741G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,5.249,\N,\N,TSPEAR
507368,21:45992641:A>G,NM_144991.2:c.83-4752T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,1.48,0.0008,1KG_AFR_AF,TSPEAR
507369,21:45992654:G>A,NM_144991.2:c.83-4765C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,5.666,\N,\N,TSPEAR
507370,21:45992677:T>C,NM_144991.2:c.83-4788A>G,\N,\N,1/11,Benign,\N,intron_variant,1.821,0.0061,1KG_AFR_AF,TSPEAR
507371,21:45992691:G>C,NM_144991.2:c.83-4802C>G,\N,\N,1/11,Benign,\N,intron_variant,0.599,0.0371,1KG_AFR_AF,TSPEAR
507372,21:45992694:T>C,NM_144991.2:c.83-4805A>G,\N,\N,1/11,Benign,\N,intron_variant,1.985,0.1589,1KG_AFR_AF,TSPEAR
507373,21:45992717:G>GAC,NM_144991.2:c.83-4830_83-4829dup,\N,\N,1/11,Unknown significance,\N,intron_variant,6.393,\N,\N,TSPEAR
507374,21:45992717:G>GACAC,NM_144991.2:c.83-4832_83-4829dup,\N,\N,1/11,Unknown significance,\N,intron_variant,6.1,\N,\N,TSPEAR
507375,21:45992717:G>GACCACACACACAC,NM_144991.2:c.83-4829_83-4828insGTGTGTGTGTGGT,\N,\N,1/11,Benign,\N,intron_variant,\N,0.0106,1KG_AFR_AF,TSPEAR
507376,21:45992717:G>GCACAC,NM_144991.2:c.83-4829_83-4828insGTGTG,\N,\N,1/11,Benign,\N,intron_variant,\N,0.0053,1KG_AFR_AF,TSPEAR
507377,21:45992717:G>GCACACAC,NM_144991.2:c.83-4829_83-4828insGTGTGTG,\N,\N,1/11,Unknown significance,\N,intron_variant,\N,0.001,1KG_EAS_AF,TSPEAR
507378,21:45992717:G>GCACACACAC,NM_144991.2:c.83-4829_83-4828insGTGTGTGTG,\N,\N,1/11,Benign,\N,intron_variant,\N,0.0068,1KG_AFR_AF,TSPEAR
507379,21:45992717:GAC>G,NM_144991.2:c.83-4830_83-4829del,\N,\N,1/11,Unknown significance,\N,intron_variant,6.226,\N,\N,TSPEAR
507380,21:45992717:GACA>G,NM_144991.2:c.83-4831_83-4829del,\N,\N,1/11,Unknown significance,\N,intron_variant,\N,0.002,1KG_EAS_AF,TSPEAR
507381,21:45992717:GACACA>G,NM_144991.2:c.83-4833_83-4829del,\N,\N,1/11,Unknown significance,\N,intron_variant,\N,0.003,1KG_AFR_AF,TSPEAR
507382,21:45992717:GACACACACAC>G,NM_144991.2:c.83-4838_83-4829del,\N,\N,1/11,Unknown significance,\N,intron_variant,10.2,\N,\N,TSPEAR
507383,21:45992717:GACACACACACACAC>G,NM_144991.2:c.83-4842_83-4829del,\N,\N,1/11,Benign,\N,intron_variant,10.31,0.025,1KG_AFR_AF,TSPEAR
507384,21:45992717:GACACACACACACACACAC>G,NM_144991.2:c.83-4846_83-4829del,\N,\N,1/11,Benign,\N,intron_variant,\N,0.0159,1KG_EAS_AF,TSPEAR
507385,21:45992717:GACACACACACACACACACAC>G,NM_144991.2:c.83-4848_83-4829del,\N,\N,1/11,Unknown significance,\N,intron_variant,\N,0.001,1KG_EAS_AF|1KG_SAS_AF,TSPEAR
507386,21:45992717:G>GAACACACACAC,NM_144991.2:c.83-4829_83-4828insGTGTGTGTGTT,\N,\N,1/11,Benign,\N,intron_variant,\N,0.0053,1KG_AFR_AF,TSPEAR
507387,21:45992719:C>CACACACACA,NM_144991.2:c.83-4839_83-4831dup,\N,\N,1/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
507388,21:45992747:C>G,NM_144991.2:c.83-4858G>C,\N,\N,1/11,Unknown significance,\N,intron_variant,10.74,0.002,1KG_EAS_AF,TSPEAR
507389,21:45992786:G>A,NM_144991.2:c.83-4897C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,4.364,\N,\N,TSPEAR
507390,21:45992848:G>A,NM_144991.2:c.83-4959C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.796,\N,\N,TSPEAR
507391,21:45992849:T>C,NM_144991.2:c.83-4960A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,2.943,0.002,1KG_EAS_AF,TSPEAR
507392,21:45992850:G>A,NM_144991.2:c.83-4961C>T,\N,\N,1/11,Benign,\N,intron_variant,3.084,0.0159,1KG_EAS_AF,TSPEAR
507393,21:45992855:G>C,NM_144991.2:c.83-4966C>G,\N,\N,1/11,Benign,\N,intron_variant,0.145,0.1619,1KG_AFR_AF,TSPEAR
507394,21:45992859:G>A,NM_144991.2:c.83-4970C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.115,0.0008,1KG_AFR_AF,TSPEAR
507395,21:45992859:G>C,NM_144991.2:c.83-4970C>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.021,\N,\N,TSPEAR
507396,21:45992878:C>T,NM_144991.2:c.83-4989G>A,\N,\N,1/11,Benign,\N,intron_variant,0.214,0.0371,1KG_AFR_AF,TSPEAR
507397,21:45992879:G>A,NM_144991.2:c.83-4990C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,2.481,\N,\N,TSPEAR
507398,21:45992897:C>T,NM_144991.2:c.83-5008G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,5.283,0.0008,1KG_AFR_AF,TSPEAR
507399,21:45992898:A>G,NM_144991.2:c.83-5009T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,2.115,0.001,1KG_EUR_AF,TSPEAR
507400,21:45992902:T>G,NM_144991.2:c.83-5013A>C,\N,\N,1/11,Unknown significance,\N,intron_variant,1.938,\N,\N,TSPEAR
507401,21:45992913:C>G,NM_144991.2:c.83-5024G>C,\N,\N,1/11,Benign,\N,intron_variant,2.605,0.0159,1KG_EAS_AF,TSPEAR
507402,21:45992921:G>A,NM_144991.2:c.83-5032C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.458,\N,\N,TSPEAR
507403,21:45992936:G>A,NM_144991.2:c.83-5047C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.384,0.0023,1KG_AFR_AF,TSPEAR
507404,21:45992950:G>T,NM_144991.2:c.83-5061C>A,\N,\N,1/11,Unknown significance,\N,intron_variant,2.453,0.001,1KG_SAS_AF,TSPEAR
507405,21:45992951:A>AG,NM_144991.2:c.83-5063dup,\N,\N,1/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
507406,21:45992955:A>G,NM_144991.2:c.83-5066T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,0.369,\N,\N,TSPEAR
507407,21:45992956:C>T,NM_144991.2:c.83-5067G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,1.041,\N,\N,TSPEAR
507408,21:45992957:G>A,NM_144991.2:c.83-5068C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,6.259,0.001,1KG_EAS_AF,TSPEAR
507409,21:45992977:A>C,NM_144991.2:c.83-5088T>G,\N,\N,1/11,Unknown significance,\N,intron_variant,1.293,0.0008,1KG_AFR_AF,TSPEAR
507410,21:45992982:G>A,NM_144991.2:c.83-5093C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,2.031,\N,\N,TSPEAR
507411,21:45992984:T>C,NM_144991.2:c.83-5095A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.545,\N,\N,TSPEAR
507412,21:45993004:G>A,NM_144991.2:c.83-5115C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.128,0.001,1KG_SAS_AF,TSPEAR
507413,21:45993053:T>C,NM_144991.2:c.83-5164A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,2.508,0.0023,1KG_AFR_AF,TSPEAR
507414,21:45993061:C>T,NM_144991.2:c.83-5172G>A,\N,\N,1/11,Benign,\N,intron_variant,5.412,0.1899,1KG_AFR_AF,TSPEAR
507415,21:45993075:A>G,NM_144991.2:c.83-5186T>C,\N,\N,1/11,Benign,\N,intron_variant,0.152,0.1906,1KG_AFR_AF,TSPEAR
507416,21:45993113:G>A,NM_144991.2:c.83-5224C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,4.517,\N,\N,TSPEAR
507417,21:45993131:A>G,NM_144991.2:c.83-5242T>C,\N,\N,1/11,Benign,\N,intron_variant,3.16,0.1921,1KG_AFR_AF,TSPEAR
507418,21:45993149:G>A,NM_144991.2:c.83-5260C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.25,0.001,1KG_EAS_AF,TSPEAR
507419,21:45993159:G>A,NM_144991.2:c.83-5270C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,4.841,0.0031,1KG_SAS_AF,TSPEAR
507420,21:45993170:C>T,NM_144991.2:c.83-5281G>A,\N,\N,1/11,Benign,\N,intron_variant,6.753,0.152,1KG_AFR_AF,TSPEAR
507421,21:45993181:C>T,NM_144991.2:c.83-5292G>A,\N,\N,1/11,Benign,\N,intron_variant,8.573,0.152,1KG_AFR_AF,TSPEAR
507422,21:45993181:CT>TC,NM_144991.2:c.83-5293_83-5292delinsGA,\N,\N,1/11,Unknown significance,\N,intron_variant,8.391,\N,\N,TSPEAR
507423,21:45993182:T>C,NM_144991.2:c.83-5293A>G,\N,\N,1/11,Benign,\N,intron_variant,7.503,0.152,1KG_AFR_AF,TSPEAR
507424,21:45993195:C>T,NM_144991.2:c.83-5306G>A,\N,\N,1/11,Benign,\N,intron_variant,8.256,0.1543,1KG_AFR_AF,TSPEAR
507425,21:45993209:A>G,NM_144991.2:c.83-5320T>C,\N,\N,1/11,Benign,\N,intron_variant,7.211,0.1006,1KG_AFR_AF,TSPEAR
507426,21:45993257:G>A,NM_144991.2:c.83-5368C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.165,0.001,1KG_EAS_AF,TSPEAR
507427,21:45993259:A>G,NM_144991.2:c.83-5370T>C,\N,\N,1/11,Benign,\N,intron_variant,4.867,0.0121,1KG_AFR_AF,TSPEAR
507428,21:45993270:C>T,NM_144991.2:c.83-5381G>A,\N,\N,1/11,Benign,\N,intron_variant,1.252,0.1641,1KG_AFR_AF,TSPEAR
507429,21:45993280:C>T,NM_144991.2:c.83-5391G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,3.322,0.0014,1KG_AMR_AF,TSPEAR
507430,21:45993281:G>C,NM_144991.2:c.83-5392C>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.721,0.0014,1KG_AMR_AF,TSPEAR
507431,21:45993289:C>T,NM_144991.2:c.83-5400G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,5.309,\N,\N,TSPEAR
507432,21:45993295:C>T,NM_144991.2:c.83-5406G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,3.425,0.002,1KG_EUR_AF,TSPEAR
507433,21:45993311:G>A,NM_144991.2:c.83-5422C>T,\N,\N,1/11,Benign,\N,intron_variant,2.119,0.0149,1KG_EAS_AF,TSPEAR
507434,21:45993314:C>T,NM_144991.2:c.83-5425G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,1.48,\N,\N,TSPEAR
507435,21:45993315:G>T,NM_144991.2:c.83-5426C>A,\N,\N,1/11,Unknown significance,\N,intron_variant,1.682,0.001,1KG_EAS_AF,TSPEAR
507436,21:45993321:G>C,NM_144991.2:c.83-5432C>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.421,\N,\N,TSPEAR
507437,21:45993343:A>C,NM_144991.2:c.83-5454T>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.035,\N,\N,TSPEAR
507438,21:45993345:T>G,NM_144991.2:c.83-5456A>C,\N,\N,1/11,Unknown significance,\N,intron_variant,5.817,0.0008,1KG_AFR_AF,TSPEAR
507439,21:45993358:T>C,NM_144991.2:c.83-5469A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,1.105,0.001,1KG_SAS_AF,TSPEAR
507440,21:45993361:C>T,NM_144991.2:c.83-5472G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,6.001,0.001,1KG_EAS_AF,TSPEAR
507441,21:45993371:T>C,NM_144991.2:c.83-5482A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,3.326,0.0008,1KG_AFR_AF,TSPEAR
507442,21:45993374:A>G,NM_144991.2:c.83-5485T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,3.308,0.004,1KG_EAS_AF,TSPEAR
507443,21:45993378:C>T,NM_144991.2:c.83-5489G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.306,\N,\N,TSPEAR
507444,21:45993431:G>A,NM_144991.2:c.83-5542C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,11.96,\N,\N,TSPEAR
507445,21:45993445:C>T,NM_144991.2:c.83-5556G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,8.406,0.002,1KG_SAS_AF,TSPEAR
507446,21:45993462:C>G,NM_144991.2:c.83-5573G>C,\N,\N,1/11,Unknown significance,\N,intron_variant,0.129,0.0008,1KG_AFR_AF,TSPEAR
507447,21:45993536:G>T,NM_144991.2:c.83-5647C>A,\N,\N,1/11,Unknown significance,\N,intron_variant,2.049,0.002,1KG_EAS_AF,TSPEAR
507448,21:45993538:G>A,NM_144991.2:c.83-5649C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,2.658,0.0008,1KG_AFR_AF,TSPEAR
507449,21:45993544:T>C,NM_144991.2:c.83-5655A>G,\N,\N,1/11,Benign,\N,intron_variant,6.855,0.0257,1KG_AFR_AF,TSPEAR
507450,21:45993552:C>T,NM_144991.2:c.83-5663G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,8.616,\N,\N,TSPEAR
507451,21:45993561:C>G,NM_144991.2:c.83-5672G>C,\N,\N,1/11,Benign,\N,intron_variant,1.279,0.1589,1KG_AFR_AF,TSPEAR
507452,21:45993562:G>A,NM_144991.2:c.83-5673C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,5.627,\N,\N,TSPEAR
507453,21:45993578:C>T,NM_144991.2:c.83-5689G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,6.732,0.0014,1KG_AMR_AF,TSPEAR
507454,21:45993586:C>T,NM_144991.2:c.83-5697G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,6.435,0.001,1KG_SAS_AF,TSPEAR
507455,21:45993591:C>A,NM_144991.2:c.83-5702G>T,\N,\N,1/11,Benign,\N,intron_variant,3.812,0.00574174,EVS_EA_AF,TSPEAR
507456,21:45993598:T>A,NM_144991.2:c.83-5709A>T,\N,\N,1/11,Unknown significance,\N,intron_variant,4.582,0.000030756,EXAC_NFE_AF,TSPEAR
507457,21:45993600:T>G,NM_144991.2:c.83-5711A>C,\N,\N,1/11,Unknown significance,\N,intron_variant,2.35,0.0000871232,EXAC_SAS_AF,TSPEAR
507458,21:45993600:TC>T,NM_144991.2:c.83-5712del,\N,\N,1/11,Unknown significance,\N,intron_variant,1.197,0.0000871232,EXAC_SAS_AF,TSPEAR
507459,21:45993602:C>T,NM_144991.2:c.83-5713G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,1.571,0.0000866101,EXAC_SAS_AF,TSPEAR
507460,21:45993608:C>T,NM_198687.1:c.-28C>T,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,6.256,0.000116387,EXAC_EAS_AF,TSPEAR
507461,21:45993611:A>C,NM_198687.1:c.-25A>C,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,0.706,0.000102585,EXAC_AFR_AF,TSPEAR
507462,21:45993612:AC>A,NM_198687.1:c.-19del,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,1.863,0.00016559,EXAC_SAS_AF,TSPEAR
507463,21:45993613:C>A,NM_198687.1:c.-23C>A,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,8.788,0.001,1KG_EAS_AF,TSPEAR
507464,21:45993616:C>T,NM_198687.1:c.-20C>T,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,8.393,\N,\N,TSPEAR
507465,21:45993622:C>G,NM_198687.1:c.-14C>G,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,1.325,0.0000866551,EXAC_AMR_AF,TSPEAR
507466,21:45993622:C>T,NM_198687.1:c.-14C>T,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,3.342,0.001,1KG_SAS_AF,TSPEAR
507467,21:45993623:A>G,NM_198687.1:c.-13A>G,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,0.021,0.00112543,EXAC_AFR_AF,TSPEAR
507468,21:45993624:G>A,NM_198687.1:c.-12G>A,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,3.617,0.0000152472,EXAC_NFE_AF,TSPEAR
507469,21:45993626:A>C,NM_198687.1:c.-10A>C,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,0.04,0.001,1KG_SAS_AF,TSPEAR
507470,21:45993626:A>T,NM_198687.1:c.-10A>T,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,0.073,0.00114732,EVS_AA_AF,TSPEAR
507471,21:45993629:A>G,NM_198687.1:c.-7A>G,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,0.117,0.001,1KG_SAS_AF,TSPEAR
507472,21:45993631:C>T,NM_198687.1:c.-5C>T,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,4.843,0.001,1KG_EAS_AF,TSPEAR
507473,21:45993635:C>T,NM_198687.1:c.-1C>T,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,4.39,0.000458085,EVS_AA_AF,TSPEAR
507474,21:45993637:T>G,NM_198687.1:c.2T>G,NP_941960.1:p.Met1?,1/1,\N,Unknown significance,\N,start_lost,23.6,0.0000151281,EXAC_NFE_AF,TSPEAR
507475,21:45993641:C>T,NM_198687.1:c.6C>T,NP_941960.1:p.Ser2=,1/1,\N,Unknown significance,\N,synonymous_variant,16.07,0.001,1KG_EAS_AF,TSPEAR
507476,21:45993642:G>A,NM_198687.1:c.7G>A,NP_941960.1:p.Val3Ile,1/1,\N,Unknown significance,\N,missense_variant,14.3,0.000229148,EVS_AA_AF,TSPEAR
507477,21:45993643:T>A,NM_198687.1:c.8T>A,NP_941960.1:p.Val3Asp,1/1,\N,Unknown significance,\N,missense_variant,26,0.0000452489,EXAC_NFE_AF,TSPEAR
507478,21:45993643:T>C,NM_198687.1:c.8T>C,NP_941960.1:p.Val3Ala,1/1,\N,Unknown significance,\N,missense_variant,24,0.000115955,EXAC_EAS_AF,TSPEAR
507479,21:45993646:G>A,NM_198687.1:c.11G>A,NP_941960.1:p.Cys4Tyr,1/1,\N,Unknown significance,\N,missense_variant,22.1,0.000015063,EXAC_NFE_AF,TSPEAR
507480,21:45993649:C>G,NM_198687.1:c.14C>G,NP_941960.1:p.Ser5Cys,1/1,\N,Unknown significance,\N,missense_variant,25.1,\N,\N,TSPEAR
507481,21:45993653:C>T,NM_198687.1:c.18C>T,NP_941960.1:p.Ser6=,1/1,\N,Unknown significance,\N,synonymous_variant,16.35,0.000305873,EXAC_AFR_AF,TSPEAR
507482,21:45993655:A>ACCTGAGCTACAGC,NM_198687.1:c.21_33dup,NP_941960.1:p.Ser12ProfsTer14,1/1,\N,Unknown significance,\N,frameshift_variant,23.9,\N,\N,TSPEAR
507483,21:45993656:C>T,NM_198687.1:c.21C>T,NP_941960.1:p.Asp7=,1/1,\N,Unknown significance,\N,synonymous_variant,11.27,0.0000150322,EXAC_NFE_AF,TSPEAR
507484,21:45993658:T>A,NM_198687.1:c.23T>A,NP_941960.1:p.Leu8Gln,1/1,\N,Unknown significance,\N,missense_variant,24.3,0.000123962,EXAC_SAS_AF,TSPEAR
507485,21:45993665:C>T,NM_198687.1:c.30C>T,NP_941960.1:p.Tyr10=,1/1,\N,Unknown significance,\N,synonymous_variant,1.959,\N,\N,TSPEAR
507486,21:45993666:A>G,NM_198687.1:c.31A>G,NP_941960.1:p.Ser11Gly,1/1,\N,Benign,\N,missense_variant,0.001,0.0961,1KG_AFR_AF,TSPEAR
507487,21:45993668:C>G,NM_198687.1:c.33C>G,NP_941960.1:p.Ser11Arg,1/1,\N,Unknown significance,\N,missense_variant,23.4,0.0000150155,EXAC_NFE_AF,TSPEAR
507488,21:45993672:C>T,NM_198687.1:c.37C>T,NP_941960.1:p.Arg13Cys,1/1,\N,Unknown significance,\N,missense_variant,21.5,0.000122534,EXAC_SAS_AF,TSPEAR
507489,21:45993673:G>A,NM_198687.1:c.38G>A,NP_941960.1:p.Arg13His,1/1,\N,Likely benign,\N,missense_variant,13.62,0.000702905,EVS_EA_AF,TSPEAR
507490,21:45993674:C>T,NM_198687.1:c.39C>T,NP_941960.1:p.Arg13=,1/1,\N,Unknown significance,\N,synonymous_variant,12.12,0.000061237,EXAC_SAS_AF,TSPEAR
507491,21:45993675:G>A,NM_198687.2:c.40G>A,NP_941960.2:p.Val14Ile,1/1,\N,Benign,\N,missense_variant,3.56,0.053,1KG_AFR_AF,TSPEAR
507492,21:45993677:C>CT,NM_198687.1:c.43dup,NP_941960.1:p.Cys15LeufsTer7,1/1,\N,Unknown significance,\N,frameshift_variant,24.7,0.00023175,EXAC_EAS_AF,TSPEAR
507493,21:45993681:C>T,NM_198687.1:c.46C>T,NP_941960.1:p.Leu16Phe,1/1,\N,Likely benign,\N,missense_variant,14.59,0.000234467,EVS_EA_AF,TSPEAR
507494,21:45993688:G>A,NM_198687.1:c.53G>A,NP_941960.1:p.Gly18Asp,1/1,\N,Unknown significance,\N,missense_variant,22.7,0.001,1KG_EUR_AF,TSPEAR
507495,21:45993696:G>A,NM_198687.1:c.61G>A,NP_941960.1:p.Asp21Asn,1/1,\N,Unknown significance,\N,missense_variant,23.4,0.0000300237,EXAC_NFE_AF,TSPEAR
507496,21:45993703:G>A,NM_198687.1:c.68G>A,NP_941960.1:p.Cys23Tyr,1/1,\N,Likely benign,\N,missense_variant,0.25,0.000259202,EXAC_AMR_AF,TSPEAR
507497,21:45993704:C>T,NM_198687.1:c.69C>T,NP_941960.1:p.Cys23=,1/1,\N,Unknown significance,\N,synonymous_variant,1.141,\N,\N,TSPEAR
507498,21:45993707:C>T,NM_198687.1:c.72C>T,NP_941960.1:p.Ser24=,1/1,\N,Benign,\N,synonymous_variant,8.47,0.0089,1KG_EAS_AF,TSPEAR
507499,21:45993717:C>T,NM_198687.1:c.82C>T,NP_941960.1:p.Gln28Ter,1/1,\N,Unknown significance,\N,stop_gained,33,\N,\N,TSPEAR
507500,21:45993718:A>C,NM_198687.1:c.83A>C,NP_941960.1:p.Gln28Pro,1/1,\N,Unknown significance,\N,missense_variant,22.8,\N,\N,TSPEAR
507501,21:45993720:G>A,NM_198687.1:c.85G>A,NP_941960.1:p.Val29Met,1/1,\N,Unknown significance,\N,missense_variant,23.4,0.0014,1KG_AMR_AF,TSPEAR
507502,21:45993722:G>A,NM_198687.1:c.87G>A,NP_941960.1:p.Val29=,1/1,\N,Unknown significance,\N,synonymous_variant,2.963,0.000116009,EXAC_EAS_AF,TSPEAR
507503,21:45993724:A>C,NM_198687.1:c.89A>C,NP_941960.1:p.Asp30Ala,1/1,\N,Unknown significance,\N,missense_variant,23.3,\N,\N,TSPEAR
507504,21:45993725:C>T,NM_198687.1:c.90C>T,NP_941960.1:p.Asp30=,1/1,\N,Unknown significance,\N,synonymous_variant,7.608,0.0008,1KG_AFR_AF,TSPEAR
507505,21:45993726:G>A,NM_198687.2:c.91G>A,NP_941960.2:p.Asp31Asn,1/1,\N,Unknown significance,\N,missense_variant,12.53,\N,\N,TSPEAR
507506,21:45993727:A>C,NM_198687.1:c.92A>C,NP_941960.1:p.Asp31Ala,1/1,\N,Benign,\N,missense_variant,23.6,0.133457,EXAC_EAS_AF,TSPEAR
507507,21:45993734:A>G,NM_198687.1:c.99A>G,NP_941960.1:p.Pro33=,1/1,\N,Unknown significance,\N,synonymous_variant,0.793,0.000232342,EXAC_EAS_AF,TSPEAR
507508,21:45993735:G>A,NM_198687.2:c.100G>A,NP_941960.2:p.Glu34Lys,1/1,\N,Unknown significance,\N,missense_variant,24.4,\N,\N,TSPEAR
507509,21:45993737:G>A,NM_198687.1:c.102G>A,NP_941960.1:p.Glu34=,1/1,\N,Unknown significance,\N,synonymous_variant,6.509,\N,\N,TSPEAR
507510,21:45993739:GCTGCTGCGAGCCCCC>G,NM_198687.1:c.113_127del,NP_941960.1:p.Glu38_Cys42del,1/1,\N,Unknown significance,\N,inframe_deletion,15,\N,\N,TSPEAR
507511,21:45993745:GCGAGCCCCCCTGC>G,NM_198687.1:c.111_123del,NP_941960.1:p.Glu38AlafsTer12,1/1,\N,Unknown significance,\N,frameshift_variant,29.8,\N,\N,TSPEAR
507512,21:45993746:C>T,NM_198687.1:c.111C>T,NP_941960.1:p.Cys37=,1/1,\N,Benign,\N,synonymous_variant,11.95,0.2423,1KG_SAS_AF,TSPEAR
507513,21:45993747:G>A,NM_198687.1:c.112G>A,NP_941960.1:p.Glu38Lys,1/1,\N,Unknown significance,\N,missense_variant,25.1,\N,\N,TSPEAR
507514,21:45993747:G>C,NM_198687.2:c.112G>C,NP_941960.2:p.Glu38Gln,1/1,\N,Unknown significance,\N,missense_variant,18.78,\N,\N,TSPEAR
507515,21:45993749:G>GC,NM_198687.1:c.120dup,NP_941960.1:p.Cys41LeufsTer54,1/1,\N,Unknown significance,\N,frameshift_variant,\N,\N,\N,TSPEAR
507516,21:45993749:GC>G,NM_198687.1:c.120del,NP_941960.1:p.Cys41AlafsTer13,1/1,\N,Unknown significance,\N,frameshift_variant,24.9,\N,\N,TSPEAR
507517,21:45993751:C>A,NM_198687.1:c.116C>A,NP_941960.1:p.Pro39His,1/1,\N,Unknown significance,\N,missense_variant,24.4,\N,\N,TSPEAR
507518,21:45993752:C>T,NM_198687.1:c.117C>T,NP_941960.1:p.Pro39=,1/1,\N,Unknown significance,\N,synonymous_variant,6.147,\N,\N,TSPEAR
507519,21:45993753:C>T,NM_198687.1:c.118C>T,NP_941960.1:p.Pro40Ser,1/1,\N,Likely benign,\N,missense_variant,0.148,\N,\N,TSPEAR
507520,21:45993753:CCCTGCTGCGCCCCCA>C,NM_198687.1:c.119_133del,NP_941960.1:p.Pro40_Ser45delinsArg,1/1,\N,Unknown significance,\N,inframe_deletion,12.05,\N,\N,TSPEAR
507521,21:45993754:C>G,NM_198687.1:c.119C>G,NP_941960.1:p.Pro40Arg,1/1,\N,Unknown significance,\N,missense_variant,4.909,\N,\N,TSPEAR
507522,21:45993754:CCTGCTGCGCCCCCAG>C,NM_198687.1:c.132_146del,NP_941960.1:p.Ser45_Pro49del,1/1,\N,Unknown significance,\N,inframe_deletion,12.22,\N,\N,TSPEAR
507523,21:45993757:G>C,NM_198687.1:c.122G>C,NP_941960.1:p.Cys41Ser,1/1,\N,Unknown significance,\N,missense_variant,18.77,\N,\N,TSPEAR
507524,21:45993759:T>A,NM_198687.1:c.124T>A,NP_941960.1:p.Cys42Ser,1/1,\N,Unknown significance,\N,missense_variant,22.6,\N,\N,TSPEAR
507525,21:45993759:T>G,NM_198687.1:c.124T>G,NP_941960.1:p.Cys42Gly,1/1,\N,Unknown significance,\N,missense_variant,22.2,\N,\N,TSPEAR
507526,21:45993761:C>A,NM_198687.1:c.126C>A,NP_941960.1:p.Cys42Ter,1/1,\N,Unknown significance,\N,stop_gained,24.3,\N,\N,TSPEAR
507527,21:45993761:C>CGA,NM_198687.1:c.127_128insAG,NP_941960.1:p.Ala43GlufsTer12,1/1,\N,Unknown significance,\N,frameshift_variant,22.8,\N,\N,TSPEAR
507528,21:45993761:C>T,NM_198687.1:c.126C>T,NP_941960.1:p.Cys42=,1/1,\N,Benign,\N,synonymous_variant,7.101,0.0076,1KG_AFR_AF,TSPEAR
507529,21:45993762:G>A,NM_198687.2:c.127G>A,NP_941960.2:p.Ala43Thr,1/1,\N,Unknown significance,\N,missense_variant,9.261,0.001,1KG_SAS_AF,TSPEAR
507530,21:45993762:GC>G,NM_198687.1:c.132del,NP_941960.1:p.Ser45AlafsTer9,1/1,\N,Unknown significance,\N,frameshift_variant,23.9,\N,\N,TSPEAR
507531,21:45993763:C>T,NM_198687.1:c.128C>T,NP_941960.1:p.Ala43Val,1/1,\N,Unknown significance,\N,missense_variant,22.7,\N,\N,TSPEAR
507532,21:45993764:CCCCAGCTGCTGCGCCCCG>C,NM_198687.1:c.130_147del,NP_941960.1:p.Pro44_Pro49del,1/1,\N,Unknown significance,\N,inframe_deletion,13.21,\N,\N,TSPEAR
507533,21:45993765:C>A,NM_198687.1:c.130C>A,NP_941960.1:p.Pro44Thr,1/1,\N,Unknown significance,\N,missense_variant,17.87,\N,\N,TSPEAR
507534,21:45993766:C>CGG,NM_198687.1:c.131_132insGG,NP_941960.1:p.Ser45AlafsTer10,1/1,\N,Unknown significance,\N,frameshift_variant,25.6,0.000331236,EXAC_AFR_AF,TSPEAR
507535,21:45993766:C>T,NM_198687.1:c.131C>T,NP_941960.1:p.Pro44Leu,1/1,\N,Unknown significance,\N,missense_variant,25.3,0.000331236,EXAC_AFR_AF,TSPEAR
507536,21:45993767:CAG>C,NM_198687.1:c.133_134del,NP_941960.1:p.Ser45LeufsTer49,1/1,\N,Unknown significance,\N,frameshift_variant,24.2,\N,\N,TSPEAR
507537,21:45993768:A>C,NM_198687.1:c.133A>C,NP_941960.1:p.Ser45Arg,1/1,\N,Unknown significance,\N,missense_variant,16.29,\N,\N,TSPEAR
507538,21:45993768:AGCTGCTGCGCCCCG>A,NM_198687.1:c.136_149del,NP_941960.1:p.Cys46ProfsTer44,1/1,\N,Unknown significance,\N,frameshift_variant,28.5,\N,\N,TSPEAR
507539,21:45993769:G>C,NM_198687.1:c.134G>C,NP_941960.1:p.Ser45Thr,1/1,\N,Likely benign,\N,missense_variant,13.66,\N,\N,TSPEAR
507540,21:45993771:T>G,NM_198687.1:c.136T>G,NP_941960.1:p.Cys46Gly,1/1,\N,Unknown significance,\N,missense_variant,23,\N,\N,TSPEAR
507541,21:45993776:C>T,NM_198687.1:c.141C>T,NP_941960.1:p.Cys47=,1/1,\N,Unknown significance,\N,synonymous_variant,9.246,0.002,1KG_EAS_AF,TSPEAR
507542,21:45993777:G>A,NM_198687.1:c.142G>A,NP_941960.1:p.Ala48Thr,1/1,\N,Unknown significance,\N,missense_variant,15.22,0.00131165,EVS_AA_AF,TSPEAR
507543,21:45993781:C>T,NM_198687.2:c.146C>T,NP_941960.2:p.Pro49Leu,1/1,\N,Unknown significance,\N,missense_variant,19.62,0.001,1KG_EAS_AF,TSPEAR
507544,21:45993782:G>A,NM_198687.1:c.147G>A,NP_941960.1:p.Pro49=,1/1,\N,Unknown significance,\N,synonymous_variant,7.765,0.0038,1KG_AFR_AF,TSPEAR
507545,21:45993787:C>G,NM_198687.1:c.152C>G,NP_941960.1:p.Pro51Arg,1/1,\N,Unknown significance,\N,missense_variant,19.19,\N,\N,TSPEAR
507546,21:45993790:G>C,NM_198687.1:c.155G>C,NP_941960.1:p.Cys52Ser,1/1,\N,Unknown significance,\N,missense_variant,13.77,\N,\N,TSPEAR
507547,21:45993796:G>C,NM_198687.1:c.161G>C,NP_941960.1:p.Ser54Thr,1/1,\N,Benign,\N,missense_variant,0.002,0.00616333,EVS_AA_AF,TSPEAR
507548,21:45993807:A>G,NM_198687.1:c.172A>G,NP_941960.1:p.Thr58Ala,1/1,\N,Likely benign,\N,missense_variant,10.2,\N,\N,TSPEAR
507549,21:45993811:C>A,NM_198687.1:c.176C>A,NP_941960.1:p.Pro59Gln,1/1,\N,Unknown significance,\N,missense_variant,24.2,\N,\N,TSPEAR
507550,21:45993815:G>A,NM_198687.1:c.180G>A,NP_941960.1:p.Val60=,1/1,\N,Unknown significance,\N,synonymous_variant,2.398,\N,\N,TSPEAR
507551,21:45993819:C>T,NM_198687.1:c.184C>T,NP_941960.1:p.Arg62Cys,1/1,\N,Benign,\N,missense_variant,12.43,0.768582,EXAC_NFE_AF,TSPEAR
507552,21:45993820:G>A,NM_198687.2:c.185G>A,NP_941960.2:p.Arg62His,1/1,\N,Unknown significance,\N,missense_variant,26.3,\N,\N,TSPEAR
507553,21:45993824:G>A,NM_198687.1:c.189G>A,NP_941960.1:p.Val63=,1/1,\N,Unknown significance,\N,synonymous_variant,5.444,0.0017802,EVS_EA_AF,TSPEAR
507554,21:45993828:A>C,NM_198687.1:c.193A>C,NP_941960.1:p.Ser65Arg,1/1,\N,Likely benign,\N,missense_variant,15.07,\N,\N,TSPEAR
507555,21:45993828:A>G,NM_198687.1:c.193A>G,NP_941960.1:p.Ser65Gly,1/1,\N,Likely benign,\N,missense_variant,22.7,\N,\N,TSPEAR
507556,21:45993830:C>T,NM_198687.1:c.195C>T,NP_941960.1:p.Ser65=,1/1,\N,Unknown significance,\N,synonymous_variant,9.26,0.0015,1KG_AFR_AF,TSPEAR
507557,21:45993841:C>A,NM_198687.1:c.206C>A,NP_941960.1:p.Pro69Gln,1/1,\N,Benign,\N,missense_variant,0.002,0.0344671,EXAC_AFR_AF,TSPEAR
507558,21:45993841:C>G,NM_198687.2:c.206C>G,NP_941960.2:p.Pro69Arg,1/1,\N,Benign,\N,missense_variant,0.003,0.4395,1KG_AFR_AF,TSPEAR
507559,21:45993851:C>T,NM_198687.1:c.216C>T,NP_941960.1:p.Cys72=,1/1,\N,Benign,\N,synonymous_variant,7.12,0.129722,EXAC_AFR_AF,TSPEAR
507560,21:45993852:G>A,NM_198687.1:c.217G>A,NP_941960.1:p.Glu73Lys,1/1,\N,Likely benign,\N,missense_variant,16.47,0.00011936,EVS_EA_AF,TSPEAR
507561,21:45993854:GC>G,NM_198687.1:c.222del,NP_941960.1:p.Ser75AlafsTer105,1/1,\N,Unknown significance,\N,frameshift_variant,4.023,0.0000161938,EXAC_NFE_AF,TSPEAR
507562,21:45993873:G>C,NM_198687.1:c.238G>C,NP_941960.1:p.Gly80Arg,1/1,\N,Likely benign,\N,missense_variant,8.153,\N,\N,TSPEAR
507563,21:45993880:C>A,NM_198687.1:c.245C>A,NP_941960.1:p.Thr82Asn,1/1,\N,Unknown significance,\N,missense_variant,17.23,\N,\N,TSPEAR
507564,21:45993880:C>T,NM_198687.1:c.245C>T,NP_941960.1:p.Thr82Ile,1/1,\N,Likely benign,\N,missense_variant,12.89,\N,\N,TSPEAR
507565,21:45993886:C>T,NM_198687.1:c.251C>T,NP_941960.1:p.Ser84Phe,1/1,\N,Unknown significance,\N,missense_variant,22.4,\N,\N,TSPEAR
507566,21:45993893:G>A,NM_198687.1:c.258G>A,NP_941960.1:p.Thr86=,1/1,\N,Unknown significance,\N,synonymous_variant,11.93,\N,\N,TSPEAR
507567,21:45993894:C>T,NM_198687.1:c.259C>T,NP_941960.1:p.Pro87Ser,1/1,\N,Likely benign,\N,missense_variant,11.45,\N,\N,TSPEAR
507568,21:45993899:G>A,NM_198687.1:c.264G>A,NP_941960.1:p.Ser88=,1/1,\N,Unknown significance,\N,synonymous_variant,8.194,\N,\N,TSPEAR
507569,21:45993904:G>A,NM_198687.1:c.269G>A,NP_941960.1:p.Cys90Tyr,1/1,\N,Unknown significance,\N,missense_variant,22,\N,\N,TSPEAR
507570,21:45993907:A>G,NM_198687.1:c.272A>G,NP_941960.1:p.Gln91Arg,1/1,\N,Unknown significance,\N,missense_variant,12.69,\N,\N,TSPEAR
507571,21:45993909:C>T,NM_198687.1:c.274C>T,NP_941960.1:p.Gln92Ter,1/1,\N,Unknown significance,\N,stop_gained,35,\N,\N,TSPEAR
507572,21:45993911:G>A,NM_198687.1:c.276G>A,NP_941960.1:p.Gln92=,1/1,\N,Unknown significance,\N,synonymous_variant,2.697,0.000486381,EVS_AA_AF,TSPEAR
507573,21:45993911:G>T,NM_198687.2:c.276G>T,NP_941960.2:p.Gln92His,1/1,\N,Unknown significance,\N,missense_variant,20.5,\N,\N,TSPEAR
507574,21:45993916:GCTGCCAGCTGGCTTGCTGTGCCTCCTCCCC>G,NM_198687.1:c.290_319del,NP_941960.1:p.Leu97_Gln106del,1/1,\N,Unknown significance,\N,inframe_deletion,12.27,\N,\N,TSPEAR
507575,21:45993924:C>A,NM_198687.1:c.289C>A,NP_941960.1:p.Leu97Met,1/1,\N,Likely benign,\N,missense_variant,12.7,\N,\N,TSPEAR
507576,21:45993924:C>G,NM_198687.1:c.289C>G,NP_941960.1:p.Leu97Val,1/1,\N,Likely benign,\N,missense_variant,10.26,0.0008,1KG_AFR_AF,TSPEAR
507577,21:45993925:T>C,NM_198687.1:c.290T>C,NP_941960.1:p.Leu97Pro,1/1,\N,Likely benign,\N,missense_variant,0.001,\N,\N,TSPEAR
507578,21:45993927:G>A,NM_198687.1:c.292G>A,NP_941960.1:p.Ala98Thr,1/1,\N,Likely benign,\N,missense_variant,0.134,\N,\N,TSPEAR
507579,21:45993931:G>A,NM_198687.1:c.296G>A,NP_941960.1:p.Cys99Tyr,1/1,\N,Unknown significance,\N,missense_variant,13.71,\N,\N,TSPEAR
507580,21:45993935:T>C,NM_198687.1:c.300T>C,NP_941960.1:p.Cys100=,1/1,\N,Unknown significance,\N,synonymous_variant,0.001,0.0015,1KG_AFR_AF,TSPEAR
507581,21:45993936:G>A,NM_198687.1:c.301G>A,NP_941960.1:p.Ala101Thr,1/1,\N,Likely benign,\N,missense_variant,0.001,\N,\N,TSPEAR
507582,21:45993937:C>A,NM_198687.1:c.302C>A,NP_941960.1:p.Ala101Asp,1/1,\N,Likely benign,\N,missense_variant,9.373,0.00123183,EVS_EA_AF,TSPEAR
507583,21:45993943:C>T,NM_198687.1:c.308C>T,NP_941960.1:p.Ser103Phe,1/1,\N,Unknown significance,\N,missense_variant,14.36,0.001,1KG_SAS_AF,TSPEAR
507584,21:45993945:C>T,NM_198687.1:c.310C>T,NP_941960.1:p.Pro104Ser,1/1,\N,Likely benign,\N,missense_variant,0.139,\N,\N,TSPEAR
507585,21:45993947:C>T,NM_198687.1:c.312C>T,NP_941960.1:p.Pro104=,1/1,\N,Unknown significance,\N,synonymous_variant,7.393,\N,\N,TSPEAR
507586,21:45993950:C>T,NM_198687.1:c.315C>T,NP_941960.1:p.Cys105=,1/1,\N,Unknown significance,\N,synonymous_variant,6.151,\N,\N,TSPEAR
507587,21:45993951:C>T,NM_198687.1:c.316C>T,NP_941960.1:p.Gln106Ter,1/1,\N,Unknown significance,\N,stop_gained,28.2,\N,\N,TSPEAR
507588,21:45993953:G>T,NM_198687.1:c.318G>T,NP_941960.1:p.Gln106His,1/1,\N,Unknown significance,\N,missense_variant,12.4,\N,\N,TSPEAR
507589,21:45993954:C>G,NM_198687.1:c.319C>G,NP_941960.1:p.Gln107Glu,1/1,\N,Likely benign,\N,missense_variant,0.197,0.003,1KG_AFR_AF,TSPEAR
507590,21:45993965:C>A,NM_198687.1:c.330C>A,NP_941960.1:p.Cys110Ter,1/1,\N,Unknown significance,\N,stop_gained,24,\N,\N,TSPEAR
507591,21:45993965:C>T,NM_198687.1:c.330C>T,NP_941960.1:p.Cys110=,1/1,\N,Unknown significance,\N,synonymous_variant,7.624,0.00190658,EVS_AA_AF,TSPEAR
507592,21:45993966:G>A,NM_198687.1:c.331G>A,NP_941960.1:p.Val111Met,1/1,\N,Likely benign,\N,missense_variant,3.892,0.001,1KG_SAS_AF,TSPEAR
507593,21:45993971:C>T,NM_198687.1:c.336C>T,NP_941960.1:p.Pro112=,1/1,\N,Unknown significance,\N,synonymous_variant,9.621,0.0015,1KG_AFR_AF,TSPEAR
507594,21:45993972:G>A,NM_198687.1:c.337G>A,NP_941960.1:p.Val113Ile,1/1,\N,Likely benign,\N,missense_variant,0.675,\N,\N,TSPEAR
507595,21:45993973:T>C,NM_198687.1:c.338T>C,NP_941960.1:p.Val113Ala,1/1,\N,Likely benign,\N,missense_variant,0.047,\N,\N,TSPEAR
507596,21:45993974:C>T,NM_198687.1:c.339C>T,NP_941960.1:p.Val113=,1/1,\N,Unknown significance,\N,synonymous_variant,4.807,\N,\N,TSPEAR
507597,21:45993975:T>G,NM_198687.1:c.340T>G,NP_941960.1:p.Cys114Gly,1/1,\N,Unknown significance,\N,missense_variant,9.534,\N,\N,TSPEAR
507598,21:45993982:A>G,NM_198687.1:c.347A>G,NP_941960.1:p.Lys116Arg,1/1,\N,Likely benign,\N,missense_variant,0.004,\N,\N,TSPEAR
507599,21:45993984:A>C,NM_198687.1:c.349A>C,NP_941960.1:p.Thr117Pro,1/1,\N,Likely benign,\N,missense_variant,0.001,\N,\N,TSPEAR
507600,21:45993988:T>A,NM_198687.1:c.353T>A,NP_941960.1:p.Val118Asp,1/1,\N,Unknown significance,\N,missense_variant,14.34,\N,\N,TSPEAR
507601,21:45993989:C>G,NM_198687.1:c.354C>G,NP_941960.1:p.Val118=,1/1,\N,Unknown significance,\N,synonymous_variant,4.141,\N,\N,TSPEAR
507602,21:45993990:T>C,NM_198687.1:c.355T>C,NP_941960.1:p.Cys119Arg,1/1,\N,Benign,\N,missense_variant,13.15,0.113079,EVS_AA_AF,TSPEAR
507603,21:45993999:C>T,NM_198687.1:c.364C>T,NP_941960.1:p.Pro122Ser,1/1,\N,Unknown significance,\N,missense_variant,9.071,0.000227066,EVS_AA_AF,TSPEAR
507604,21:45994001:T>C,NM_198687.1:c.366T>C,NP_941960.1:p.Pro122=,1/1,\N,Unknown significance,\N,synonymous_variant,0.005,\N,\N,TSPEAR
507605,21:45994006:G>A,NM_198687.1:c.371G>A,NP_941960.1:p.Cys124Tyr,1/1,\N,Unknown significance,\N,missense_variant,10.23,\N,\N,TSPEAR
507606,21:45994011:G>A,NM_198687.1:c.376G>A,NP_941960.1:p.Val126Met,1/1,\N,Likely benign,\N,missense_variant,0.03,\N,\N,TSPEAR
507607,21:45994011:G>C,NM_198687.1:c.376G>C,NP_941960.1:p.Val126Leu,1/1,\N,Likely benign,\N,missense_variant,0.005,\N,\N,TSPEAR
507608,21:45994013:G>A,NM_198687.1:c.378G>A,NP_941960.1:p.Val126=,1/1,\N,Unknown significance,\N,synonymous_variant,0.056,\N,\N,TSPEAR
507609,21:45994014:C>T,NM_198687.1:c.379C>T,NP_941960.1:p.Pro127Ser,1/1,\N,Likely benign,\N,missense_variant,0.711,0.001,1KG_EUR_AF|1KG_SAS_AF,TSPEAR
507610,21:45994016:C>T,NM_198687.1:c.381C>T,NP_941960.1:p.Pro127=,1/1,\N,Unknown significance,\N,synonymous_variant,8.597,0.001,1KG_EUR_AF,TSPEAR
507611,21:45994017:G>A,NM_198687.1:c.382G>A,NP_941960.1:p.Val128Ile,1/1,\N,Likely benign,\N,missense_variant,0.016,0.00227066,EVS_AA_AF,TSPEAR
507612,21:45994021:GC>G,NM_198687.1:c.387del,NP_941960.1:p.Cys130ValfsTer50,1/1,\N,Unknown significance,\N,frameshift_variant,19.54,0.0000968054,EXAC_AFR_AF,TSPEAR
507613,21:45994023:T>A,NM_198687.1:c.388T>A,NP_941960.1:p.Cys130Ser,1/1,\N,Likely benign,\N,missense_variant,0.087,0.003,1KG_AFR_AF,TSPEAR
507614,21:45994024:G>A,NM_198687.1:c.389G>A,NP_941960.1:p.Cys130Tyr,1/1,\N,Likely benign,\N,missense_variant,0.32,\N,\N,TSPEAR
507615,21:45994031:T>G,NM_198687.1:c.396T>G,NP_941960.1:p.Asp132Glu,1/1,\N,Likely benign,\N,missense_variant,0.002,\N,\N,TSPEAR
507616,21:45994032:T>A,NM_198687.1:c.397T>A,NP_941960.1:p.Ser133Thr,1/1,\N,Likely benign,\N,missense_variant,0.002,0.000227066,EVS_AA_AF,TSPEAR
507617,21:45994032:T>C,NM_198687.1:c.397T>C,NP_941960.1:p.Ser133Pro,1/1,\N,Likely benign,\N,missense_variant,0.002,\N,\N,TSPEAR
507618,21:45994059:C>T,NM_198687.1:c.424C>T,NP_941960.1:p.Gln142Ter,1/1,\N,Unknown significance,\N,stop_gained,26.6,\N,\N,TSPEAR
507619,21:45994061:G>A,NM_198687.1:c.426G>A,NP_941960.1:p.Gln142=,1/1,\N,Benign,\N,synonymous_variant,0.013,0.0149,1KG_EAS_AF,TSPEAR
507620,21:45994062:T>C,NM_198687.1:c.427T>C,NP_941960.1:p.Ser143Pro,1/1,\N,Likely benign,\N,missense_variant,0.002,\N,\N,TSPEAR
507621,21:45994063:C>T,NM_198687.1:c.428C>T,NP_941960.1:p.Ser143Leu,1/1,\N,Likely benign,\N,missense_variant,16.23,\N,\N,TSPEAR
507622,21:45994064:A>G,NM_198687.1:c.429A>G,NP_941960.1:p.Ser143=,1/1,\N,Unknown significance,\N,synonymous_variant,0.005,\N,\N,TSPEAR
507623,21:45994066:C>T,NM_198687.1:c.431C>T,NP_941960.1:p.Ala144Val,1/1,\N,Likely benign,\N,missense_variant,3.629,\N,\N,TSPEAR
507624,21:45994075:C>T,NM_198687.1:c.440C>T,NP_941960.1:p.Thr147Ile,1/1,\N,Likely benign,\N,missense_variant,0.116,\N,\N,TSPEAR
507625,21:45994077:T>A,NM_198687.1:c.442T>A,NP_941960.1:p.Ser148Thr,1/1,\N,Likely benign,\N,missense_variant,0.003,\N,\N,TSPEAR
507626,21:45994077:T>C,NM_198687.1:c.442T>C,NP_941960.1:p.Ser148Pro,1/1,\N,Likely benign,\N,missense_variant,0.005,\N,\N,TSPEAR
507627,21:45994079:C>T,NM_198687.1:c.444C>T,NP_941960.1:p.Ser148=,1/1,\N,Unknown significance,\N,synonymous_variant,2.108,0.001,1KG_EAS_AF,TSPEAR
507628,21:45994080:T>C,NM_198687.1:c.445T>C,NP_941960.1:p.Ser149Pro,1/1,\N,Likely benign,\N,missense_variant,0.179,\N,\N,TSPEAR
507629,21:45994082:C>T,NM_198687.1:c.447C>T,NP_941960.1:p.Ser149=,1/1,\N,Unknown significance,\N,synonymous_variant,5.02,0.001,1KG_EAS_AF,TSPEAR
507630,21:45994084:C>T,NM_198687.1:c.449C>T,NP_941960.1:p.Pro150Leu,1/1,\N,Likely benign,\N,missense_variant,0.008,\N,\N,TSPEAR
507631,21:45994088:C>A,NM_198687.1:c.453C>A,NP_941960.1:p.Cys151Ter,1/1,\N,Unknown significance,\N,stop_gained,23.9,\N,\N,TSPEAR
507632,21:45994088:C>T,NM_198687.1:c.453C>T,NP_941960.1:p.Cys151=,1/1,\N,Unknown significance,\N,synonymous_variant,0.142,\N,\N,TSPEAR
507633,21:45994089:C>A,NM_198687.1:c.454C>A,NP_941960.1:p.Gln152Lys,1/1,\N,Likely benign,\N,missense_variant,0.005,\N,\N,TSPEAR
507634,21:45994092:C>A,NM_198687.1:c.457C>A,NP_941960.1:p.Gln153Lys,1/1,\N,Likely benign,\N,missense_variant,0.004,\N,\N,TSPEAR
507635,21:45994095:G>T,NM_198687.1:c.460G>T,NP_941960.1:p.Ala154Ser,1/1,\N,Likely benign,\N,missense_variant,0.001,\N,\N,TSPEAR
507636,21:45994097:C>T,NM_198687.1:c.462C>T,NP_941960.1:p.Ala154=,1/1,\N,Unknown significance,\N,synonymous_variant,2.493,\N,\N,TSPEAR
507637,21:45994103:T>G,NM_198687.1:c.468T>G,NP_941960.1:p.Cys156Trp,1/1,\N,Unknown significance,\N,missense_variant,11,\N,\N,TSPEAR
507638,21:45994105:T>C,NM_198687.1:c.470T>C,NP_941960.1:p.Val157Ala,1/1,\N,Benign,\N,missense_variant,0.002,0.028658,EVS_AA_AF,TSPEAR
507639,21:45994107:C>G,NM_198687.1:c.472C>G,NP_941960.1:p.Pro158Ala,1/1,\N,Unknown significance,\N,missense_variant,0.008,\N,\N,TSPEAR
507640,21:45994110:A>G,NM_198687.1:c.475A>G,NP_941960.1:p.Ile159Val,1/1,\N,Likely benign,\N,missense_variant,0.001,\N,\N,TSPEAR
507641,21:45994120:A>T,NM_198687.1:c.485A>T,NP_941960.1:p.Lys162Met,1/1,\N,Likely benign,\N,missense_variant,0.114,\N,\N,TSPEAR
507642,21:45994125:G>A,NM_198687.1:c.490G>A,NP_941960.1:p.Val164Ile,1/1,\N,Benign,\N,missense_variant,0.091,0.00824305,EVS_AA_AF,TSPEAR
507643,21:45994127:C>G,NM_198687.1:c.492C>G,NP_941960.1:p.Val164=,1/1,\N,Unknown significance,\N,synonymous_variant,0.313,\N,\N,TSPEAR
507644,21:45994130:C>T,NM_198687.1:c.495C>T,NP_941960.1:p.Cys165=,1/1,\N,Unknown significance,\N,synonymous_variant,0.629,\N,\N,TSPEAR
507645,21:45994135:G>A,NM_198687.1:c.500G>A,NP_941960.1:p.Gly167Glu,1/1,\N,Likely benign,\N,missense_variant,0.001,0.0023,1KG_AFR_AF,TSPEAR
507646,21:45994137:A>G,NM_198687.1:c.502A>G,NP_941960.1:p.Ile168Val,1/1,\N,Likely benign,\N,missense_variant,0.001,0.0023,1KG_AFR_AF,TSPEAR
507647,21:45994138:T>A,NM_198687.1:c.503T>A,NP_941960.1:p.Ile168Asn,1/1,\N,Likely benign,\N,missense_variant,0.327,0.0023,1KG_AFR_AF,TSPEAR
507648,21:45994138:T>C,NM_198687.1:c.503T>C,NP_941960.1:p.Ile168Thr,1/1,\N,Benign,\N,missense_variant,0.002,0.00731132,EVS_AA_AF,TSPEAR
507649,21:45994144:C>T,NM_198687.2:c.509C>T,NP_941960.2:p.Ser170Phe,1/1,\N,Likely benign,\N,missense_variant,5.341,\N,\N,TSPEAR
507650,21:45994147:C>T,NM_198687.1:c.512C>T,NP_941960.1:p.Ser171Leu,1/1,\N,Likely benign,\N,missense_variant,0.007,\N,\N,TSPEAR
507651,21:45994148:G>A,NM_198687.1:c.513G>A,NP_941960.1:p.Ser171=,1/1,\N,Unknown significance,\N,synonymous_variant,0.242,0.001,1KG_SAS_AF,TSPEAR
507652,21:45994150:G>A,NM_198687.1:c.515G>A,NP_941960.1:p.Cys172Tyr,1/1,\N,Unknown significance,\N,missense_variant,6.619,\N,\N,TSPEAR
507653,21:45994158:C>G,NM_198687.1:c.523C>G,NP_941960.1:p.Gln175Glu,1/1,\N,Likely benign,\N,missense_variant,3.071,\N,\N,TSPEAR
507654,21:45994163:T>TA,NM_198687.1:c.529dup,NP_941960.1:p.Ser177LysfsTer16,1/1,\N,Unknown significance,\N,frameshift_variant,23.1,\N,\N,TSPEAR
507655,21:45994163:T>TAGCTGTGTG,NM_198687.1:c.538_546dup,NP_941960.1:p.Cys181_Ser183dup,1/1,\N,Unknown significance,\N,inframe_insertion,3.682,\N,\N,TSPEAR
507656,21:45994170:G>C,NM_198687.1:c.535G>C,NP_941960.1:p.Val179Leu,1/1,\N,Likely benign,\N,missense_variant,2.76,\N,\N,TSPEAR
507657,21:45994177:G>A,NM_198687.1:c.542G>A,NP_941960.1:p.Cys181Tyr,1/1,\N,Likely benign,\N,missense_variant,5.056,\N,\N,TSPEAR
507658,21:45994184:C>T,NM_198687.1:c.549C>T,NP_941960.1:p.Ser183=,1/1,\N,Unknown significance,\N,synonymous_variant,6.271,\N,\N,TSPEAR
507659,21:45994187:C>T,NM_198687.1:c.552C>T,NP_941960.1:p.Ser184=,1/1,\N,Unknown significance,\N,synonymous_variant,7.231,0.001,1KG_EAS_AF,TSPEAR
507660,21:45994196:CCAGG>C,NM_198687.1:c.563_566del,NP_941960.1:p.Gln188ArgfsTer138,1/1,\N,Unknown significance,\N,frameshift_variant,23.5,\N,\N,TSPEAR
507661,21:45994201:C>T,NM_198687.1:c.566C>T,NP_941960.1:p.Ala189Val,1/1,\N,Likely benign,\N,missense_variant,4.453,0.0014,1KG_AMR_AF,TSPEAR
507662,21:45994202:G>A,NM_198687.1:c.567G>A,NP_941960.1:p.Ala189=,1/1,\N,Unknown significance,\N,synonymous_variant,6.687,0.00111259,EXAC_AFR_AF,TSPEAR
507663,21:45994202:G>GA,NM_198687.1:c.567_568insA,NP_941960.1:p.Val190SerfsTer3,1/1,\N,Unknown significance,\N,frameshift_variant,22.8,0.000111259,EXAC_AFR_AF,TSPEAR
507664,21:45994203:G>A,NM_198687.1:c.568G>A,NP_941960.1:p.Val190Ile,1/1,\N,Likely benign,\N,missense_variant,0.116,0.0008,1KG_AFR_AF,TSPEAR
507665,21:45994203:G>T,NM_198687.1:c.568G>T,NP_941960.1:p.Val190Phe,1/1,\N,Likely benign,\N,missense_variant,1.405,\N,\N,TSPEAR
507666,21:45994204:T>C,NM_198687.1:c.569T>C,NP_941960.1:p.Val190Ala,1/1,\N,Likely benign,\N,missense_variant,0.002,\N,\N,TSPEAR
507667,21:45994204:T>TGAC,NM_198687.1:c.569_570insGAC,NP_941960.1:p.Val190_Cys191insThr,1/1,\N,Unknown significance,\N,inframe_insertion,0.649,\N,\N,TSPEAR
507668,21:45994205:C>T,NM_198687.1:c.570C>T,NP_941960.1:p.Val190=,1/1,\N,Unknown significance,\N,synonymous_variant,4.88,\N,\N,TSPEAR
507669,21:45994208:T>C,NM_198687.1:c.573T>C,NP_941960.1:p.Cys191=,1/1,\N,Unknown significance,\N,synonymous_variant,0.003,0.00116659,EVS_AA_AF,TSPEAR
507670,21:45994217:C>T,NM_198687.1:c.582C>T,NP_941960.1:p.Ser194=,1/1,\N,Unknown significance,\N,synonymous_variant,4.869,\N,\N,TSPEAR
507671,21:45994232:C>T,NM_198687.1:c.597C>T,NP_941960.1:p.Gly199=,1/1,\N,Unknown significance,\N,synonymous_variant,4.975,0.001,1KG_EAS_AF,TSPEAR
507672,21:45994237:T>C,NM_198687.1:c.602T>C,NP_941960.1:p.Ile201Thr,1/1,\N,Likely benign,\N,missense_variant,0.002,\N,\N,TSPEAR
507673,21:45994246:G>A,NM_198687.1:c.611G>A,NP_941960.1:p.Cys204Tyr,1/1,\N,Unknown significance,\N,missense_variant,17.86,\N,\N,TSPEAR
507674,21:45994249:C>T,NM_198687.1:c.614C>T,NP_941960.1:p.Thr205Met,1/1,\N,Benign,\N,missense_variant,15.81,0.0053,1KG_AFR_AF,TSPEAR
507675,21:45994250:G>A,NM_198687.1:c.615G>A,NP_941960.1:p.Thr205=,1/1,\N,Unknown significance,\N,synonymous_variant,11.48,0.001,1KG_EAS_AF,TSPEAR
507676,21:45994251:C>G,NM_198687.1:c.616C>G,NP_941960.1:p.Pro206Ala,1/1,\N,Unknown significance,\N,missense_variant,6.577,\N,\N,TSPEAR
507677,21:45994253:C>T,NM_198687.1:c.618C>T,NP_941960.1:p.Pro206=,1/1,\N,Unknown significance,\N,synonymous_variant,9.428,0.0000866701,EXAC_AMR_AF,TSPEAR
507678,21:45994256:G>A,NM_198687.1:c.621G>A,NP_941960.1:p.Ser207=,1/1,\N,Unknown significance,\N,synonymous_variant,8.914,0.001,1KG_EUR_AF,TSPEAR
507679,21:45994262:C>T,NM_198687.1:c.627C>T,NP_941960.1:p.Cys209=,1/1,\N,Unknown significance,\N,synonymous_variant,10.23,\N,\N,TSPEAR
507680,21:45994265:G>T,NM_198687.1:c.630G>T,NP_941960.1:p.Gln210His,1/1,\N,Unknown significance,\N,missense_variant,15.3,0.0000865801,EXAC_AMR_AF,TSPEAR
507681,21:45994273:GCTGCCAGCCGGCTTGCTGCACCTCCTCCTC>G,NM_198687.1:c.647_676del,NP_941960.1:p.Pro216_Gln225del,1/1,\N,Unknown significance,\N,inframe_deletion,14.27,\N,\N,TSPEAR
507682,21:45994278:C>A,NM_198687.1:c.643C>A,NP_941960.1:p.Gln215Lys,1/1,\N,Likely benign,\N,missense_variant,13.33,0.000181752,EXAC_SAS_AF,TSPEAR
507683,21:45994282:C>A,NM_198687.1:c.647C>A,NP_941960.1:p.Pro216Gln,1/1,\N,Unknown significance,\N,missense_variant,23.6,0.0000302435,EXAC_NFE_AF,TSPEAR
507684,21:45994282:C>T,NM_198687.1:c.647C>T,NP_941960.1:p.Pro216Leu,1/1,\N,Benign,\N,missense_variant,24.1,0.0106,1KG_AFR_AF,TSPEAR
507685,21:45994283:G>A,NM_198687.1:c.648G>A,NP_941960.1:p.Pro216=,1/1,\N,Unknown significance,\N,synonymous_variant,8.841,0.002,1KG_EAS_AF,TSPEAR
507686,21:45994284:G>A,NM_198687.1:c.649G>A,NP_941960.1:p.Ala217Thr,1/1,\N,Likely benign,\N,missense_variant,11.81,\N,\N,TSPEAR
507687,21:45994289:C>G,NM_198687.1:c.654C>G,NP_941960.1:p.Cys218Trp,1/1,\N,Unknown significance,\N,missense_variant,23.4,0.0000605694,EXAC_SAS_AF,TSPEAR
507688,21:45994292:C>T,NM_198687.1:c.657C>T,NP_941960.1:p.Cys219=,1/1,\N,Benign,\N,synonymous_variant,10.17,0.005,1KG_EAS_AF,TSPEAR
507689,21:45994293:A>G,NM_198687.1:c.658A>G,NP_941960.1:p.Thr220Ala,1/1,\N,Likely benign,\N,missense_variant,3.743,\N,\N,TSPEAR
507690,21:45994298:C>T,NM_198687.1:c.663C>T,NP_941960.1:p.Ser221=,1/1,\N,Unknown significance,\N,synonymous_variant,13.19,\N,\N,TSPEAR
507691,21:45994300:C>T,NM_198687.1:c.665C>T,NP_941960.1:p.Ser222Phe,1/1,\N,Unknown significance,\N,missense_variant,23.5,0.000226963,EVS_AA_AF,TSPEAR
507692,21:45994302:T>C,NM_198687.1:c.667T>C,NP_941960.1:p.Ser223Pro,1/1,\N,Likely benign,\N,missense_variant,10.16,\N,\N,TSPEAR
507693,21:45994302:T>TCCC,NM_198687.1:c.669_670insCCC,NP_941960.1:p.Ser223_Cys224insPro,1/1,\N,Unknown significance,\N,inframe_insertion,11.66,\N,\N,TSPEAR
507694,21:45994303:C>T,NM_198687.1:c.668C>T,NP_941960.1:p.Ser223Phe,1/1,\N,Unknown significance,\N,missense_variant,23.3,0.0000301087,EXAC_NFE_AF,TSPEAR
507695,21:45994306:G>C,NM_198687.1:c.671G>C,NP_941960.1:p.Cys224Ser,1/1,\N,Unknown significance,\N,missense_variant,15.63,0.000102417,EXAC_AFR_AF,TSPEAR
507696,21:45994314:G>T,NM_198687.1:c.679G>T,NP_941960.1:p.Ala227Ser,1/1,\N,Likely benign,\N,missense_variant,0.002,0.000203707,EXAC_AFR_AF,TSPEAR
507697,21:45994315:C>A,NM_198687.1:c.680C>A,NP_941960.1:p.Ala227Asp,1/1,\N,Likely benign,\N,missense_variant,15.89,0.000060562,EXAC_SAS_AF,TSPEAR
507698,21:45994315:C>T,NM_198687.1:c.680C>T,NP_941960.1:p.Ala227Val,1/1,\N,Likely benign,\N,missense_variant,2.06,\N,\N,TSPEAR
507699,21:45994322:C>T,NM_198687.1:c.687C>T,NP_941960.1:p.Cys229=,1/1,\N,Unknown significance,\N,synonymous_variant,8.973,0.00110375,EXAC_OTH_AF,TSPEAR
507700,21:45994323:G>A,NM_198687.1:c.688G>A,NP_941960.1:p.Val230Met,1/1,\N,Likely benign,\N,missense_variant,7.259,0.000777336,EXAC_AMR_AF,TSPEAR
507701,21:45994324:T>C,NM_198687.1:c.689T>C,NP_941960.1:p.Val230Ala,1/1,\N,Likely benign,\N,missense_variant,0.004,0.0015,1KG_AFR_AF,TSPEAR
507702,21:45994326:CCCGTCTGCTGCAAGA>C,NM_198687.1:c.693_707del,NP_941960.1:p.Thr236_Lys240del,1/1,\N,Unknown significance,\N,inframe_deletion,9.795,\N,\N,TSPEAR
507703,21:45994328:C>T,NM_198687.1:c.693C>T,NP_941960.1:p.Pro231=,1/1,\N,Unknown significance,\N,synonymous_variant,10.94,\N,\N,TSPEAR
507704,21:45994328:CGTCTGCTGCAAGACT>C,NM_198687.1:c.706_720del,NP_941960.1:p.Thr236_Lys240del,1/1,\N,Unknown significance,\N,inframe_deletion,9.875,\N,\N,TSPEAR
507705,21:45994329:G>A,NM_198687.1:c.694G>A,NP_941960.1:p.Val232Ile,1/1,\N,Likely benign,\N,missense_variant,2.156,0.000116279,EVS_EA_AF,TSPEAR
507706,21:45994333:G>A,NM_198687.1:c.698G>A,NP_941960.1:p.Cys233Tyr,1/1,\N,Unknown significance,\N,missense_variant,6.854,0.000060562,EXAC_SAS_AF,TSPEAR
507707,21:45994333:G>T,NM_198687.1:c.698G>T,NP_941960.1:p.Cys233Phe,1/1,\N,Unknown significance,\N,missense_variant,9.639,0.000115634,EXAC_EAS_AF,TSPEAR
507708,21:45994335:T>G,NM_198687.1:c.700T>G,NP_941960.1:p.Cys234Gly,1/1,\N,Benign,\N,missense_variant,14.1,0.0575,1KG_AFR_AF,TSPEAR
507709,21:45994341:A>C,NM_198687.1:c.706A>C,NP_941960.1:p.Thr236Pro,1/1,\N,Likely benign,\N,missense_variant,0.001,\N,\N,TSPEAR
507710,21:45994344:G>A,NM_198687.1:c.709G>A,NP_941960.1:p.Val237Ile,1/1,\N,Likely benign,\N,missense_variant,2.653,0.0000149903,EXAC_NFE_AF,TSPEAR
507711,21:45994346:C>G,NM_198687.1:c.711C>G,NP_941960.1:p.Val237=,1/1,\N,Unknown significance,\N,synonymous_variant,0.499,\N,\N,TSPEAR
507712,21:45994347:T>A,NM_198687.1:c.712T>A,NP_941960.1:p.Cys238Ser,1/1,\N,Likely benign,\N,missense_variant,1.38,\N,\N,TSPEAR
507713,21:45994352:C>T,NM_198687.1:c.717C>T,NP_941960.1:p.Cys239=,1/1,\N,Unknown significance,\N,synonymous_variant,0.468,\N,\N,TSPEAR
507714,21:45994353:A>G,NM_198687.1:c.718A>G,NP_941960.1:p.Lys240Glu,1/1,\N,Likely benign,\N,missense_variant,0.001,\N,\N,TSPEAR
507715,21:45994354:A>T,NM_198687.1:c.719A>T,NP_941960.1:p.Lys240Met,1/1,\N,Likely benign,\N,missense_variant,0.003,\N,\N,TSPEAR
507716,21:45994358:T>C,NM_198687.1:c.723T>C,NP_941960.1:p.Pro241=,1/1,\N,Unknown significance,\N,synonymous_variant,0.003,\N,\N,TSPEAR
507717,21:45994361:G>A,NM_198687.1:c.726G>A,NP_941960.1:p.Val242=,1/1,\N,Unknown significance,\N,synonymous_variant,0.187,0.000116279,EVS_EA_AF,TSPEAR
507718,21:45994361:G>T,NM_198687.1:c.726G>T,NP_941960.1:p.Val242=,1/1,\N,Unknown significance,\N,synonymous_variant,0.126,0.000115634,EXAC_EAS_AF,TSPEAR
507719,21:45994364:C>T,NM_198687.1:c.729C>T,NP_941960.1:p.Cys243=,1/1,\N,Unknown significance,\N,synonymous_variant,1.448,0.000194024,EXAC_AFR_AF,TSPEAR
507720,21:45994365:T>A,NM_198687.1:c.730T>A,NP_941960.1:p.Ser244Thr,1/1,\N,Likely benign,\N,missense_variant,0.17,0.000121124,EXAC_SAS_AF,TSPEAR
507721,21:45994366:C>G,NM_198687.1:c.731C>G,NP_941960.1:p.Ser244Cys,1/1,\N,Likely benign,\N,missense_variant,0.045,0.0000149862,EXAC_NFE_AF,TSPEAR
507722,21:45994369:A>G,NM_198687.1:c.734A>G,NP_941960.1:p.Glu245Gly,1/1,\N,Likely benign,\N,missense_variant,0.608,\N,\N,TSPEAR
507723,21:45994371:G>T,NM_198687.1:c.736G>T,NP_941960.1:p.Asp246Tyr,1/1,\N,Likely benign,\N,missense_variant,4.378,0.00087277,EXAC_AFR_AF,TSPEAR
507724,21:45994372:A>C,NM_198687.1:c.737A>C,NP_941960.1:p.Asp246Ala,1/1,\N,Likely benign,\N,missense_variant,0.002,\N,\N,TSPEAR
507725,21:45994377:T>C,NM_198687.1:c.742T>C,NP_941960.1:p.Ser248Pro,1/1,\N,Likely benign,\N,missense_variant,5.225,0.0008,1KG_AFR_AF,TSPEAR
507726,21:45994385:C>T,NM_198687.1:c.750C>T,NP_941960.1:p.Cys250=,1/1,\N,Unknown significance,\N,synonymous_variant,11.56,0.000774593,EXAC_AFR_AF,TSPEAR
507727,21:45994388:C>T,NM_198687.1:c.753C>T,NP_941960.1:p.Cys251=,1/1,\N,Unknown significance,\N,synonymous_variant,12.19,0.001,1KG_EUR_AF,TSPEAR
507728,21:45994389:C>A,NM_198687.1:c.754C>A,NP_941960.1:p.Gln252Lys,1/1,\N,Unknown significance,\N,missense_variant,14.54,0.000115554,EXAC_EAS_AF,TSPEAR
507729,21:45994392:C>T,NM_198687.1:c.757C>T,NP_941960.1:p.Gln253Ter,1/1,\N,Unknown significance,\N,stop_gained,37,0.0029,1KG_AMR_AF,TSPEAR
507730,21:45994394:G>C,NM_198687.1:c.759G>C,NP_941960.1:p.Gln253His,1/1,\N,Likely benign,\N,missense_variant,14.53,0.0000863707,EXAC_AMR_AF,TSPEAR
507731,21:45994396:C>G,NM_198687.1:c.761C>G,NP_941960.1:p.Ser254Cys,1/1,\N,Unknown significance,\N,missense_variant,19.65,0.000290641,EXAC_AFR_AF,TSPEAR
507732,21:45994405:A>T,NM_198687.1:c.770A>T,NP_941960.1:p.Gln257Leu,1/1,\N,Unknown significance,\N,missense_variant,22.8,0.000060562,EXAC_SAS_AF,TSPEAR
507733,21:45994407:C>T,NM_198687.1:c.772C>T,NP_941960.1:p.Pro258Ser,1/1,\N,Unknown significance,\N,missense_variant,14.94,0.001,1KG_EAS_AF,TSPEAR
507734,21:45994408:C>A,NM_198687.1:c.773C>A,NP_941960.1:p.Pro258Gln,1/1,\N,Unknown significance,\N,missense_variant,23.6,0.0000968054,EXAC_AFR_AF,TSPEAR
507735,21:45994408:C>G,NM_198687.1:c.773C>G,NP_941960.1:p.Pro258Arg,1/1,\N,Unknown significance,\N,missense_variant,23.1,0.0012718,EXAC_SAS_AF,TSPEAR
507736,21:45994408:C>T,NM_198687.1:c.773C>T,NP_941960.1:p.Pro258Leu,1/1,\N,Unknown significance,\N,missense_variant,24.1,0.0000968054,EXAC_AFR_AF,TSPEAR
507737,21:45994409:G>A,NM_198687.1:c.774G>A,NP_941960.1:p.Pro258=,1/1,\N,Benign,\N,synonymous_variant,6.736,0.00930549,EVS_AA_AF,TSPEAR
507738,21:45994409:G>T,NM_198687.1:c.774G>T,NP_941960.1:p.Pro258=,1/1,\N,Unknown significance,\N,synonymous_variant,3.606,0.0000299769,EXAC_NFE_AF,TSPEAR
507739,21:45994410:G>A,NM_198687.1:c.775G>A,NP_941960.1:p.Ala259Thr,1/1,\N,Likely benign,\N,missense_variant,9.06,0.0000149871,EXAC_NFE_AF,TSPEAR
507740,21:45994413:T>C,NM_198687.1:c.778T>C,NP_941960.1:p.Cys260Arg,1/1,\N,Unknown significance,\N,missense_variant,19.37,0.00103998,EXAC_EAS_AF,TSPEAR
507741,21:45994414:G>T,NM_198687.1:c.779G>T,NP_941960.1:p.Cys260Phe,1/1,\N,Unknown significance,\N,missense_variant,22.5,0.000116279,EVS_EA_AF,TSPEAR
507742,21:45994417:G>T,NM_198687.1:c.782G>T,NP_941960.1:p.Cys261Phe,1/1,\N,Unknown significance,\N,missense_variant,22.9,0.0000299742,EXAC_NFE_AF,TSPEAR
507743,21:45994420:C>T,NM_198687.1:c.785C>T,NP_941960.1:p.Thr262Ile,1/1,\N,Unknown significance,\N,missense_variant,14.58,0.0000149867,EXAC_NFE_AF,TSPEAR
507744,21:45994427:T>C,NM_198687.1:c.792T>C,NP_941960.1:p.Ser264=,1/1,\N,Benign,\N,synonymous_variant,0.03,0.1853,1KG_AFR_AF,TSPEAR
507745,21:45994429:C>T,NM_198687.1:c.794C>T,NP_941960.1:p.Pro265Leu,1/1,\N,Likely benign,\N,missense_variant,17.79,\N,\N,TSPEAR
507746,21:45994437:C>T,NM_198687.1:c.802C>T,NP_941960.1:p.Gln268Ter,1/1,\N,Unknown significance,\N,stop_gained,35,0.0000149853,EXAC_NFE_AF,TSPEAR
507747,21:45994438:A>T,NM_198687.1:c.803A>T,NP_941960.1:p.Gln268Leu,1/1,\N,Likely benign,\N,missense_variant,0.367,\N,\N,TSPEAR
507748,21:45994449:G>GCCTCCTCCCCC,NM_198687.1:c.814_815insCCTCCTCCCCC,NP_941960.1:p.Val272AlafsTer59,1/1,\N,Unknown significance,\N,frameshift_variant,22.3,\N,\N,TSPEAR
507749,21:45994450:TGCCTGTCTGCTGCAA>T,NM_198687.1:c.822_836del,NP_941960.1:p.Cys280_Val284del,1/1,\N,Unknown significance,\N,inframe_deletion,11.93,\N,\N,TSPEAR
507750,21:45994452:C>T,NM_198687.1:c.817C>T,NP_941960.1:p.Pro273Ser,1/1,\N,Likely benign,\N,missense_variant,8.096,0.0000149912,EXAC_NFE_AF,TSPEAR
507751,21:45994455:G>C,NM_198687.1:c.820G>C,NP_941960.1:p.Val274Leu,1/1,\N,Likely benign,\N,missense_variant,0.02,0.0008,1KG_AFR_AF,TSPEAR
507752,21:45994457:C>G,NM_198687.1:c.822C>G,NP_941960.1:p.Val274=,1/1,\N,Unknown significance,\N,synonymous_variant,4.073,0.001,1KG_EAS_AF,TSPEAR
507753,21:45994457:CTGCTGCAAGCCTGTG>C,NM_198687.1:c.837_851del,NP_941960.1:p.Cys280_Val284del,1/1,\N,Unknown significance,\N,inframe_deletion,12.02,0.0000149903,EXAC_NFE_AF,TSPEAR
507754,21:45994472:G>C,NM_198687.1:c.837G>C,NP_941960.1:p.Val279=,1/1,\N,Unknown significance,\N,synonymous_variant,0.43,\N,\N,TSPEAR
507755,21:45994472:GTGCTGCAAGCCTGTCGGCTCTGTGCCCATC>G,NM_198687.1:c.842_871del,NP_941960.1:p.Cys281_Cys290del,1/1,\N,Unknown significance,\N,inframe_deletion,8.239,\N,\N,TSPEAR
507756,21:45994476:T>A,NM_198687.1:c.841T>A,NP_941960.1:p.Cys281Ser,1/1,\N,Unknown significance,\N,missense_variant,9.055,0.000060562,EXAC_SAS_AF,TSPEAR
507757,21:45994485:G>A,NM_198687.1:c.850G>A,NP_941960.1:p.Val284Ile,1/1,\N,Likely benign,\N,missense_variant,0.335,0.000060562,EXAC_SAS_AF,TSPEAR
507758,21:45994487:C>T,NM_198687.1:c.852C>T,NP_941960.1:p.Val284=,1/1,\N,Unknown significance,\N,synonymous_variant,10.4,0.000116279,EVS_EA_AF,TSPEAR
507759,21:45994488:G>A,NM_198687.1:c.853G>A,NP_941960.1:p.Gly285Ser,1/1,\N,Unknown significance,\N,missense_variant,1.247,0.0000605694,EXAC_SAS_AF,TSPEAR
507760,21:45994488:G>T,NM_198687.1:c.853G>T,NP_941960.1:p.Gly285Cys,1/1,\N,Benign,\N,missense_variant,2.772,0.3812,1KG_AFR_AF,TSPEAR
507761,21:45994490:C>G,NM_198687.2:c.855C>G,NP_941960.2:p.Cys285Trp,1/1,\N,Unknown significance,\N,missense_variant,1.568,0.000116279,EVS_EA_AF,TSPEAR
507762,21:45994492:C>G,NM_198687.1:c.857C>G,NP_941960.1:p.Ser286Cys,1/1,\N,Likely benign,\N,missense_variant,0.001,0.0000863856,EXAC_AMR_AF,TSPEAR
507763,21:45994496:G>A,NM_198687.1:c.861G>A,NP_941960.1:p.Val287=,1/1,\N,Unknown significance,\N,synonymous_variant,0.62,0.000116279,EVS_EA_AF,TSPEAR
507764,21:45994500:A>ATCT,NM_198687.1:c.866_868dup,NP_941960.1:p.Ile289_Cys290insPhe,1/1,\N,Unknown significance,\N,inframe_insertion,0.003,0.000060562,EXAC_SAS_AF,TSPEAR
507765,21:45994507:C>G,NM_198687.1:c.872C>G,NP_941960.1:p.Ser291Cys,1/1,\N,Likely benign,\N,missense_variant,3.596,\N,\N,TSPEAR
507766,21:45994510:G>A,NM_198687.1:c.875G>A,NP_941960.1:p.Gly292Glu,1/1,\N,Likely benign,\N,missense_variant,0.001,\N,\N,TSPEAR
507767,21:45994513:C>A,NM_198687.1:c.878C>A,NP_941960.1:p.Ala293Asp,1/1,\N,Likely benign,\N,missense_variant,0.019,\N,\N,TSPEAR
507768,21:45994519:C>G,NM_198687.1:c.884C>G,NP_941960.1:p.Ser295Cys,1/1,\N,Likely benign,\N,missense_variant,9.456,0.000347222,EXAC_EAS_AF,TSPEAR
507769,21:45994521:C>A,NM_198687.1:c.886C>A,NP_941960.1:p.Leu296Met,1/1,\N,Likely benign,\N,missense_variant,4.358,0.000115741,EXAC_EAS_AF,TSPEAR
507770,21:45994521:C>T,NM_198687.1:c.886C>T,NP_941960.1:p.Leu296=,1/1,\N,Unknown significance,\N,synonymous_variant,7.782,0.000115741,EXAC_EAS_AF,TSPEAR
507771,21:45994522:T>C,NM_198687.1:c.887T>C,NP_941960.1:p.Leu296Pro,1/1,\N,Likely benign,\N,missense_variant,6.531,0.000115741,EXAC_EAS_AF,TSPEAR
507772,21:45994523:G>A,NM_198687.1:c.888G>A,NP_941960.1:p.Leu296=,1/1,\N,Unknown significance,\N,synonymous_variant,4.004,0.000115741,EXAC_EAS_AF,TSPEAR
507773,21:45994530:C>T,NM_198687.1:c.895C>T,NP_941960.1:p.Gln299Ter,1/1,\N,Unknown significance,\N,stop_gained,37,0.000060562,EXAC_SAS_AF,TSPEAR
507774,21:45994541:C>T,NM_198687.1:c.906C>T,NP_941960.1:p.Ser302=,1/1,\N,Unknown significance,\N,synonymous_variant,10.71,0.0000149844,EXAC_NFE_AF,TSPEAR
507775,21:45994544:C>T,NM_198687.1:c.909C>T,NP_941960.1:p.Cys303=,1/1,\N,Unknown significance,\N,synonymous_variant,11.3,\N,\N,TSPEAR
507776,21:45994545:C>T,NM_198687.1:c.910C>T,NP_941960.1:p.Gln304Ter,1/1,\N,Unknown significance,\N,stop_gained,36,0.0000299688,EXAC_NFE_AF,TSPEAR
507777,21:45994549:C>A,NM_198687.1:c.914C>A,NP_941960.1:p.Pro305Gln,1/1,\N,Unknown significance,\N,missense_variant,23,0.0000863707,EXAC_AMR_AF,TSPEAR
507778,21:45994550:A>G,NM_198687.1:c.915A>G,NP_941960.1:p.Pro305=,1/1,\N,Unknown significance,\N,synonymous_variant,0.122,0.0008,1KG_AFR_AF,TSPEAR
507779,21:45994551:G>A,NM_198687.1:c.916G>A,NP_941960.1:p.Ala306Thr,1/1,\N,Likely benign,\N,missense_variant,0.022,0.0000605694,EXAC_SAS_AF,TSPEAR
507780,21:45994556:C>T,NM_198687.1:c.921C>T,NP_941960.1:p.Cys307=,1/1,\N,Unknown significance,\N,synonymous_variant,7.565,0.000116279,EVS_EA_AF,TSPEAR
507781,21:45994557:T>TG,NM_198687.1:c.923dup,NP_941960.1:p.Cys308TrpfsTer37,1/1,\N,Unknown significance,\N,frameshift_variant,28.4,0.0000963948,EXAC_AFR_AF,TSPEAR
507782,21:45994560:A>G,NM_198687.1:c.925A>G,NP_941960.1:p.Thr309Ala,1/1,\N,Likely benign,\N,missense_variant,1.389,\N,\N,TSPEAR
507783,21:45994561:C>A,NM_198687.1:c.926C>A,NP_941960.1:p.Thr309Asn,1/1,\N,Likely benign,\N,missense_variant,10.53,0.001,1KG_EUR_AF,TSPEAR
507784,21:45994563:T>C,NM_198687.1:c.928T>C,NP_941960.1:p.Ser310Pro,1/1,\N,Likely benign,\N,missense_variant,4.289,0.000121153,EXAC_SAS_AF,TSPEAR
507785,21:45994563:T>G,NM_198687.1:c.928T>G,NP_941960.1:p.Ser310Ala,1/1,\N,Likely benign,\N,missense_variant,3.456,0.0000605767,EXAC_SAS_AF,TSPEAR
507786,21:45994564:C>T,NM_198687.1:c.929C>T,NP_941960.1:p.Ser310Phe,1/1,\N,Likely benign,\N,missense_variant,18.72,\N,\N,TSPEAR
507787,21:45994570:A>C,NM_198687.1:c.935A>C,NP_941960.1:p.Gln312Pro,1/1,\N,Likely benign,\N,missense_variant,0.12,\N,\N,TSPEAR
507788,21:45994571:A>C,NM_198687.1:c.936A>C,NP_941960.1:p.Gln312His,1/1,\N,Unknown significance,\N,missense_variant,0.312,\N,\N,TSPEAR
507789,21:45994572:A>T,NM_198687.1:c.937A>T,NP_941960.1:p.Ser313Cys,1/1,\N,Likely benign,\N,missense_variant,0.002,\N,\N,TSPEAR
507790,21:45994573:G>A,NM_198687.1:c.938G>A,NP_941960.1:p.Ser313Asn,1/1,\N,Unknown significance,\N,missense_variant,18.29,0.000029967,EXAC_NFE_AF,TSPEAR
507791,21:45994575:C>T,NM_198687.1:c.940C>T,NP_941960.1:p.Gln314Ter,1/1,\N,Unknown significance,\N,stop_gained,35,0.0000964692,EXAC_AFR_AF,TSPEAR
507792,21:45994578:C>A,NM_198687.1:c.943C>A,NP_941960.1:p.Gln315Lys,1/1,\N,Likely benign,\N,missense_variant,8.382,0.000232072,EXAC_EAS_AF,TSPEAR
507793,21:45994578:C>G,NM_198687.1:c.943C>G,NP_941960.1:p.Gln315Glu,1/1,\N,Likely benign,\N,missense_variant,0.638,0.000014984,EXAC_NFE_AF,TSPEAR
507794,21:45994580:G>A,NM_198687.1:c.945G>A,NP_941960.1:p.Gln315=,1/1,\N,Unknown significance,\N,synonymous_variant,0.1,0.0000965065,EXAC_AFR_AF,TSPEAR
507795,21:45994582:G>C,NM_198687.1:c.947G>C,NP_941960.1:p.Gly316Ala,1/1,\N,Likely benign,\N,missense_variant,0.001,\N,\N,TSPEAR
507796,21:45994585:G>A,NM_198687.1:c.950G>A,NP_941960.1:p.Cys317Tyr,1/1,\N,Likely benign,\N,missense_variant,7.284,0.000014984,EXAC_NFE_AF,TSPEAR
507797,21:45994590:G>A,NM_198687.1:c.955G>A,NP_941960.1:p.Val319Met,1/1,\N,Likely benign,\N,missense_variant,6.535,0.000060562,EXAC_SAS_AF,TSPEAR
507798,21:45994595:C>T,NM_198687.1:c.960C>T,NP_941960.1:p.Pro320=,1/1,\N,Unknown significance,\N,synonymous_variant,10.07,0.000014984,EXAC_NFE_AF,TSPEAR
507799,21:45994596:G>A,NM_198687.1:c.961G>A,NP_941960.1:p.Val321Ile,1/1,\N,Benign,\N,missense_variant,4.647,0.0106673,EVS_AA_AF,TSPEAR
507800,21:45994598:C>T,NM_198687.1:c.963C>T,NP_941960.1:p.Val321=,1/1,\N,Unknown significance,\N,synonymous_variant,7.74,0.000014984,EXAC_NFE_AF,TSPEAR
507801,21:45994607:G>C,NM_198687.1:c.972G>C,NP_941960.1:p.Lys324Asn,1/1,\N,Unknown significance,\N,missense_variant,10.24,\N,\N,TSPEAR
507802,21:45994608:C>A,NM_198687.1:c.973C>A,NP_941960.1:p.Pro325Thr,1/1,\N,Benign,\N,missense_variant,10.71,0.012413,EXAC_EAS_AF,TSPEAR
507803,21:45994608:C>G,NM_198687.1:c.973C>G,NP_941960.1:p.Pro325Ala,1/1,\N,Unknown significance,\N,missense_variant,12.65,0.000014984,EXAC_NFE_AF,TSPEAR
507804,21:45994611:G>A,NM_198687.1:c.976G>A,NP_941960.1:p.Val326Met,1/1,\N,Likely benign,\N,missense_variant,13.2,\N,\N,TSPEAR
507805,21:45994611:G>GTC,NM_198687.1:c.977_978insCT,NP_941960.1:p.Ser327Ter,1/1,\N,Unknown significance,\N,frameshift_variant,24.7,\N,\N,TSPEAR
507806,21:45994613:G>GCTTCAAACCC,NM_198687.1:c.978_979insCTTCAAACCC,NP_941960.1:p.Ser327LeufsTer21,1/1,\N,Unknown significance,\N,frameshift_variant,21.8,\N,\N,TSPEAR
507807,21:45994615:G>T,NM_198687.1:c.980G>T,NP_941960.1:p.Ser327Ile,1/1,\N,Unknown significance,\N,missense_variant,19.68,\N,\N,TSPEAR
507808,21:45994620:G>T,NM_198687.1:c.985G>T,NP_941960.1:p.Val329Leu,1/1,\N,Likely benign,\N,missense_variant,1.392,\N,\N,TSPEAR
507809,21:45994635:G>A,NM_198687.1:c.1000G>A,NP_941960.1:p.Gly334Arg,1/1,\N,Likely benign,\N,missense_variant,1.579,0.0000149835,EXAC_NFE_AF,TSPEAR
507810,21:45994636:G>A,NM_198687.1:c.1001G>A,NP_941960.1:p.Gly334Glu,1/1,\N,Likely benign,\N,missense_variant,0.002,0.001,1KG_SAS_AF,TSPEAR
507811,21:45994637:G>C,NM_198687.1:c.1002G>C,NP_941960.1:p.Gly334=,1/1,\N,Unknown significance,\N,synonymous_variant,0.053,0.000060562,EXAC_SAS_AF,TSPEAR
507812,21:45994642:C>A,NM_198687.1:c.1007C>A,NP_941960.1:p.Ser336Tyr,1/1,\N,Unknown significance,\N,missense_variant,16.3,0.000060562,EXAC_SAS_AF,TSPEAR
507813,21:45994646:T>C,NM_198687.1:c.1011T>C,NP_941960.1:p.Ser337=,1/1,\N,Unknown significance,\N,synonymous_variant,0.002,0.0000863856,EXAC_AMR_AF,TSPEAR
507814,21:45994663:C>G,NM_198687.1:c.1028C>G,NP_941960.1:p.Ser343Cys,1/1,\N,Likely benign,\N,missense_variant,14,0.0000149849,EXAC_NFE_AF,TSPEAR
507815,21:45994676:A>G,NM_198687.1:c.1041A>G,NP_941960.1:p.Pro347=,1/1,\N,Unknown significance,\N,synonymous_variant,0.376,\N,\N,TSPEAR
507816,21:45994678:C>G,NM_198687.1:c.1043C>G,NP_941960.1:p.Ala348Gly,1/1,\N,Likely benign,\N,missense_variant,12.5,0.00004496,EXAC_NFE_AF,TSPEAR
507817,21:45994679:TTGCTGCACCACCTCC>T,NM_198687.1:c.1052_1066del,NP_941960.1:p.Thr351_Cys355del,1/1,\N,Unknown significance,\N,inframe_deletion,17.52,0.000096432,EXAC_AFR_AF,TSPEAR
507818,21:45994680:T>A,NM_198687.1:c.1045T>A,NP_941960.1:p.Cys349Ser,1/1,\N,Likely benign,\N,missense_variant,10.78,0.0000149867,EXAC_NFE_AF,TSPEAR
507819,21:45994684:G>C,NM_198687.1:c.1049G>C,NP_941960.1:p.Cys350Ser,1/1,\N,Unknown significance,\N,missense_variant,11.58,0.0000864155,EXAC_AMR_AF,TSPEAR
507820,21:45994685:C>T,NM_198687.1:c.1050C>T,NP_941960.1:p.Cys350=,1/1,\N,Unknown significance,\N,synonymous_variant,9.969,\N,\N,TSPEAR
507821,21:45994689:A>T,NM_198687.1:c.1054A>T,NP_941960.1:p.Thr352Ser,1/1,\N,Benign,\N,missense_variant,1.355,0.0121,1KG_AFR_AF,TSPEAR
507822,21:45994696:G>A,NM_198687.1:c.1061G>A,NP_941960.1:p.Cys354Tyr,1/1,\N,Unknown significance,\N,missense_variant,23.6,0.000116279,EVS_EA_AF,TSPEAR
507823,21:45994708:C>A,NM_198687.1:c.1073C>A,NP_941960.1:p.Ser358Tyr,1/1,\N,Unknown significance,\N,missense_variant,23.7,0.0000605914,EXAC_SAS_AF,TSPEAR
507824,21:45994709:C>G,NM_198687.1:c.1074C>G,NP_941960.1:p.Ser358=,1/1,\N,Unknown significance,\N,synonymous_variant,13.15,\N,\N,TSPEAR
507825,21:45994712:C>T,NM_198687.1:c.1077C>T,NP_941960.1:p.Ser359=,1/1,\N,Unknown significance,\N,synonymous_variant,15.13,\N,\N,TSPEAR
507826,21:45994714:C>T,NM_198687.1:c.1079C>T,NP_941960.1:p.Ser360Phe,1/1,\N,Unknown significance,\N,missense_variant,23.1,0.0000864753,EXAC_AMR_AF,TSPEAR
507827,21:45994715:C>T,NM_198687.1:c.1080C>T,NP_941960.1:p.Ser360=,1/1,\N,Unknown significance,\N,synonymous_variant,16.93,\N,\N,TSPEAR
507828,21:45994716:G>A,NM_198687.1:c.1081G>A,NP_941960.1:p.Val361Met,1/1,\N,Unknown significance,\N,missense_variant,20.8,0.001,1KG_EUR_AF,TSPEAR
507829,21:45994716:G>C,NM_198687.1:c.1081G>C,NP_941960.1:p.Val361Leu,1/1,\N,Likely benign,\N,missense_variant,19.63,0.0000450113,EXAC_NFE_AF,TSPEAR
507830,21:45994725:C>A,NM_198687.1:c.1090C>A,NP_941960.1:p.Leu364Ile,1/1,\N,Likely benign,\N,missense_variant,9.186,0.0000150092,EXAC_NFE_AF,TSPEAR
507831,21:45994726:T>G,NM_198687.1:c.1091T>G,NP_941960.1:p.Leu364Arg,1/1,\N,Unknown significance,\N,missense_variant,21.7,\N,\N,TSPEAR
507832,21:45994728:T>C,NM_198687.1:c.1093T>C,NP_941960.1:p.Cys365Arg,1/1,\N,Unknown significance,\N,missense_variant,22.9,0.0031,1KG_SAS_AF,TSPEAR
507833,21:45994731:C>T,NM_198687.1:c.1096C>T,NP_941960.1:p.Arg366Cys,1/1,\N,Unknown significance,\N,missense_variant,23.9,0.000909091,EXAC_FIN_AF,TSPEAR
507834,21:45994732:G>A,NM_198687.1:c.1097G>A,NP_941960.1:p.Arg366His,1/1,\N,Unknown significance,\N,missense_variant,23,0.0000600781,EXAC_NFE_AF,TSPEAR
507835,21:45994734:C>G,NM_198687.1:c.1099C>G,NP_941960.1:p.Pro367Ala,1/1,\N,Unknown significance,\N,missense_variant,23.3,\N,\N,TSPEAR
507836,21:45994734:C>T,NM_198687.1:c.1099C>T,NP_941960.1:p.Pro367Ser,1/1,\N,Unknown significance,\N,missense_variant,24.5,\N,\N,TSPEAR
507837,21:45994736:C>G,NM_198687.1:c.1101C>G,NP_941960.1:p.Pro367=,1/1,\N,Unknown significance,\N,synonymous_variant,13.41,0.000116387,EXAC_EAS_AF,TSPEAR
507838,21:45994737:G>A,NM_198687.2:c.1102G>A,NP_941960.2:p.Val368Met,1/1,\N,Unknown significance,\N,missense_variant,23.7,0.000453926,EVS_AA_AF,TSPEAR
507839,21:45994741:G>A,NM_198687.1:c.1106G>A,NP_941960.1:p.Cys369Tyr,1/1,\N,Unknown significance,\N,missense_variant,23.6,0.0000751405,EXAC_NFE_AF,TSPEAR
507840,21:45994744:G>A,NM_198687.1:c.1109G>A,NP_941960.1:p.Arg370Lys,1/1,\N,Likely benign,\N,missense_variant,13.84,0.000121374,EXAC_SAS_AF,TSPEAR
507841,21:45994746:C>T,NM_198687.1:c.1111C>T,NP_941960.1:p.Pro371Ser,1/1,\N,Likely benign,\N,missense_variant,15.85,\N,\N,TSPEAR
507842,21:45994748:C>G,NM_198687.1:c.1113C>G,NP_941960.1:p.Pro371=,1/1,\N,Unknown significance,\N,synonymous_variant,10.74,0.00011655,EXAC_EAS_AF,TSPEAR
507843,21:45994748:C>T,NM_198687.1:c.1113C>T,NP_941960.1:p.Pro371=,1/1,\N,Unknown significance,\N,synonymous_variant,13.16,0.000198373,EXAC_AFR_AF,TSPEAR
507844,21:45994749:G>A,NM_198687.1:c.1114G>A,NP_941960.1:p.Ala372Thr,1/1,\N,Likely benign,\N,missense_variant,16.71,0.00069541,EXAC_AFR_AF,TSPEAR
507845,21:45994753:G>A,NM_198687.1:c.1118G>A,NP_941960.1:p.Cys373Tyr,1/1,\N,Unknown significance,\N,missense_variant,19.49,\N,\N,TSPEAR
507846,21:45994757:C>T,NM_198687.1:c.1122C>T,NP_941960.1:p.Cys374=,1/1,\N,Unknown significance,\N,synonymous_variant,11.86,0.0000601305,EXAC_NFE_AF,TSPEAR
507847,21:45994758:G>A,NM_198687.1:c.1123G>A,NP_941960.1:p.Val375Met,1/1,\N,Likely benign,\N,missense_variant,10.93,\N,\N,TSPEAR
507848,21:45994759:T>TGCCCGTCCCTTCCTGCTGTGC,NM_198687.1:c.1125_1145dup,NP_941960.1:p.Val377_Pro383dup,1/1,\N,Unknown significance,\N,inframe_insertion,0.897,\N,\N,TSPEAR
507849,21:45994760:G>A,NM_198687.1:c.1125G>A,NP_941960.1:p.Val375=,1/1,\N,Unknown significance,\N,synonymous_variant,4.514,0.00023359,EXAC_EAS_AF,TSPEAR
507850,21:45994761:C>A,NM_198687.1:c.1126C>A,NP_941960.1:p.Pro376Thr,1/1,\N,Unknown significance,\N,missense_variant,11.82,0.0000150344,EXAC_NFE_AF,TSPEAR
507851,21:45994763:C>G,NM_198687.1:c.1128C>G,NP_941960.1:p.Pro376=,1/1,\N,Unknown significance,\N,synonymous_variant,7.412,0.0000867453,EXAC_AMR_AF,TSPEAR
507852,21:45994763:C>T,NM_198687.1:c.1128C>T,NP_941960.1:p.Pro376=,1/1,\N,Benign,\N,synonymous_variant,10.35,0.0696,1KG_AFR_AF,TSPEAR
507853,21:45994764:G>A,NM_198687.1:c.1129G>A,NP_941960.1:p.Val377Ile,1/1,\N,Benign,\N,missense_variant,0.003,0.00655817,EXAC_SAS_AF,TSPEAR
507854,21:45994764:G>T,NM_198687.1:c.1129G>T,NP_941960.1:p.Val377Phe,1/1,\N,Likely benign,\N,missense_variant,0.003,0.000233809,EXAC_EAS_AF,TSPEAR
507855,21:45994769:T>C,NM_198687.1:c.1134T>C,NP_941960.1:p.Pro378=,1/1,\N,Unknown significance,\N,synonymous_variant,0.002,\N,\N,TSPEAR
507856,21:45994772:C>T,NM_198687.1:c.1137C>T,NP_941960.1:p.Ser379=,1/1,\N,Unknown significance,\N,synonymous_variant,8.823,0.000116986,EXAC_EAS_AF,TSPEAR
507857,21:45994777:G>A,NM_198687.1:c.1142G>A,NP_941960.1:p.Cys381Tyr,1/1,\N,Unknown significance,\N,missense_variant,20.8,0.0000150494,EXAC_NFE_AF,TSPEAR
507858,21:45994778:T>C,NM_198687.1:c.1143T>C,NP_941960.1:p.Cys381=,1/1,\N,Unknown significance,\N,synonymous_variant,0.007,\N,\N,TSPEAR
507859,21:45994781:T>C,NM_198687.1:c.1146T>C,NP_941960.1:p.Ala382=,1/1,\N,Unknown significance,\N,synonymous_variant,0.033,0.000121492,EXAC_SAS_AF,TSPEAR
507860,21:45994785:A>C,NM_198687.1:c.1150A>C,NP_941960.1:p.Thr384Pro,1/1,\N,Likely benign,\N,missense_variant,0.029,0.0000607607,EXAC_SAS_AF,TSPEAR
507861,21:45994785:A>T,NM_198687.1:c.1150A>T,NP_941960.1:p.Thr384Ser,1/1,\N,Likely benign,\N,missense_variant,0.002,0.0000607607,EXAC_SAS_AF,TSPEAR
507862,21:45994798:AAC>A,NM_198687.1:c.1164_1165del,NP_941960.1:p.Gln388HisfsTer52,1/1,\N,Unknown significance,\N,frameshift_variant,24.7,\N,\N,TSPEAR
507863,21:45994799:A>G,NM_198687.1:c.1164A>G,NP_941960.1:p.Gln388=,1/1,\N,Unknown significance,\N,synonymous_variant,6.003,0.000205634,EXAC_AFR_AF,TSPEAR
507864,21:45994800:C>G,NM_198687.1:c.1165C>G,NP_941960.1:p.Pro389Ala,1/1,\N,Unknown significance,\N,missense_variant,3.629,0.0000301668,EXAC_NFE_AF,TSPEAR
507865,21:45994801:C>G,NM_198687.1:c.1166C>G,NP_941960.1:p.Pro389Arg,1/1,\N,Benign,\N,missense_variant,21.3,0.0138046,EXAC_FIN_AF,TSPEAR
507866,21:45994807:G>A,NM_198687.1:c.1172G>A,NP_941960.1:p.Cys391Tyr,1/1,\N,Unknown significance,\N,missense_variant,8.586,\N,\N,TSPEAR
507867,21:45994808:C>T,NM_198687.1:c.1173C>T,NP_941960.1:p.Cys391=,1/1,\N,Unknown significance,\N,synonymous_variant,4.134,0.000102838,EXAC_AFR_AF,TSPEAR
507868,21:45994810:G>C,NM_198687.1:c.1175G>C,NP_941960.1:p.Cys392Ser,1/1,\N,Unknown significance,\N,missense_variant,5.374,0.000243576,EXAC_SAS_AF,TSPEAR
507869,21:45994812:C>T,NM_198687.1:c.1177C>T,NP_941960.1:p.Arg393Cys,1/1,\N,Unknown significance,\N,missense_variant,22.4,0.001,1KG_EAS_AF,TSPEAR
507870,21:45994813:G>A,NM_198687.1:c.1178G>A,NP_941960.1:p.Arg393His,1/1,\N,Likely benign,\N,missense_variant,19.9,0.004,1KG_EAS_AF,TSPEAR
507871,21:45994813:G>T,NM_198687.1:c.1178G>T,NP_941960.1:p.Arg393Leu,1/1,\N,Unknown significance,\N,missense_variant,20.2,0.0000150989,EXAC_NFE_AF,TSPEAR
507872,21:45994816:C>A,NM_198687.1:c.1181C>A,NP_941960.1:p.Pro394Gln,1/1,\N,Unknown significance,\N,missense_variant,10.31,0.000103263,EXAC_AFR_AF,TSPEAR
507873,21:45994817:A>G,NM_198687.1:c.1182A>G,NP_941960.1:p.Pro394=,1/1,\N,Unknown significance,\N,synonymous_variant,0.012,0.000206825,EXAC_AFR_AF,TSPEAR
507874,21:45994823:C>A,NM_198687.1:c.1188C>A,NP_941960.1:p.Ser396=,1/1,\N,Unknown significance,\N,synonymous_variant,11.38,0.0000151144,EXAC_NFE_AF,TSPEAR
507875,21:45994826:C>T,NM_198687.1:c.1191C>T,NP_941960.1:p.Cys397=,1/1,\N,Unknown significance,\N,synonymous_variant,10.63,0.000234797,EXAC_EAS_AF,TSPEAR
507876,21:45994827:G>A,NM_198687.1:c.1192G>A,NP_941960.1:p.Val398Met,1/1,\N,Likely benign,\N,missense_variant,13.81,0.000933998,EXAC_AFR_AF,TSPEAR
507877,21:45994830:T>C,NM_198687.1:c.1195T>C,NP_941960.1:p.Ser399Pro,1/1,\N,Unknown significance,\N,missense_variant,21.8,0.0000615612,EXAC_SAS_AF,TSPEAR
507878,21:45994833:C>G,NM_198687.1:c.1198C>G,NP_941960.1:p.Leu400Val,1/1,\N,Unknown significance,\N,missense_variant,18.68,0.000116904,EVS_EA_AF,TSPEAR
507879,21:45994840:G>A,NM_198687.1:c.1205G>A,NP_941960.1:p.Ter402=,1/1,\N,Unknown significance,\N,stop_retained_variant,6.279,0.000117261,EXAC_EAS_AF,TSPEAR
507880,21:45994841:A>C,NM_198687.1:c.1206A>C,NP_941960.1:p.Ter402CysextTer10,1/1,\N,Benign,\N,stop_lost,13.66,0.2496,1KG_AFR_AF,TSPEAR
507881,21:45994842:C>T,NM_198687.1:c.*1C>T,\N,1/1,\N,Benign,\N,3_prime_UTR_variant,6.994,0.0380402,EXAC_FIN_AF,TSPEAR
507882,21:45994843:G>A,NM_198687.1:c.*2G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,5.718,0.00333961,EXAC_NFE_AF,TSPEAR
507883,21:45994843:G>C,NM_198687.1:c.*2G>C,\N,1/1,\N,Benign,\N,3_prime_UTR_variant,1.52,0.3085,1KG_EAS_AF,TSPEAR
507884,21:45994843:G>T,NM_198687.1:c.*2G>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,2.372,0.000235128,EXAC_EAS_AF,TSPEAR
507885,21:45994844:C>G,NM_198687.1:c.*3C>G,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,4.418,0.00280308,EXAC_EAS_AF,TSPEAR
507886,21:45994845:C>A,NM_198687.1:c.*4C>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,7.933,0.0000304303,EXAC_NFE_AF,TSPEAR
507887,21:45994848:G>A,NM_198687.1:c.*7G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,0.959,0.0000647333,EXAC_SAS_AF,TSPEAR
507888,21:45994855:C>T,NM_198687.1:c.*14C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,6.812,0.000173974,EXAC_AMR_AF,TSPEAR
507889,21:45994857:C>A,NM_198687.1:c.*16C>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,8.879,0.001,1KG_EAS_AF,TSPEAR
507890,21:45994857:C>T,NM_198687.1:c.*16C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,8.463,0.000521648,EXAC_AMR_AF,TSPEAR
507891,21:45994858:G>A,NM_198687.1:c.*17G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,6.935,0.00113636,EXAC_OTH_AF,TSPEAR
507892,21:45994858:GC>G,NM_198687.1:c.*20del,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,6.697,0.0000152648,EXAC_NFE_AF,TSPEAR
507893,21:45994859:C>A,NM_198687.1:c.*18C>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,7.862,0.0000152555,EXAC_NFE_AF,TSPEAR
507894,21:45994859:C>T,NM_198687.1:c.*18C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,7.694,0.0000152555,EXAC_NFE_AF,TSPEAR
507895,21:45994862:A>G,NM_198687.1:c.*21A>G,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,0.155,0.00356398,EXAC_AMR_AF,TSPEAR
507896,21:45994862:A>T,NM_198687.1:c.*21A>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,0.103,0.0000869263,EXAC_AMR_AF,TSPEAR
507897,21:45994869:T>C,NM_198687.1:c.*28T>C,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,10.43,0.0000459095,EXAC_NFE_AF,TSPEAR
507898,21:45994872:G>C,NM_198687.1:c.*31G>C,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,0.764,0.00115207,EXAC_OTH_AF,TSPEAR
507899,21:45994875:C>T,NM_198687.1:c.*34C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,4.721,0.000104515,EXAC_AFR_AF,TSPEAR
507900,21:45994878:C>T,NM_198687.1:c.*37C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,3.056,0.001,1KG_EUR_AF,TSPEAR
507901,21:45994879:G>A,NM_198687.1:c.*38G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,0.314,0.000419992,EXAC_AFR_AF,TSPEAR
507902,21:45994882:C>T,NM_198687.1:c.*41C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,1.532,0.000926355,EVS_AA_AF,TSPEAR
507903,21:45994892:G>A,NM_198687.1:c.*51G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,9.678,0.0000154359,EXAC_NFE_AF,TSPEAR
507904,21:45994912:G>GC,NM_198687.1:c.*77dup,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,\N,\N,\N,TSPEAR
507905,21:45994917:C>G,NM_198687.1:c.*76C>G,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,7.273,\N,\N,TSPEAR
507906,21:45994926:G>A,NM_198687.1:c.*85G>A,\N,1/1,\N,Benign,\N,3_prime_UTR_variant,12.38,0.0159,1KG_EAS_AF,TSPEAR
507907,21:45994936:G>A,NM_198687.1:c.*95G>A,\N,1/1,\N,Benign,\N,3_prime_UTR_variant,2.398,0.177,1KG_AFR_AF,TSPEAR
507908,21:45994959:C>T,NM_198687.1:c.*118C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,7.388,0.001,1KG_EAS_AF,TSPEAR
507909,21:45994962:G>A,NM_198687.1:c.*121G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,2.084,\N,\N,TSPEAR
507910,21:45994997:G>A,NM_198687.2:c.*156G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,1.719,\N,\N,TSPEAR
507911,21:45995020:T>C,NM_198687.2:c.*179T>C,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,1.761,0.0043,1KG_AMR_AF,TSPEAR
507912,21:45995037:T>C,NM_198687.2:c.*196T>C,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,1.049,\N,\N,TSPEAR
507913,21:45995063:G>A,NM_198687.2:c.*222G>A,\N,1/1,\N,Benign,\N,3_prime_UTR_variant,0.812,0.0356,1KG_AFR_AF,TSPEAR
507914,21:45995066:G>A,NM_198687.2:c.*225G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,1.145,\N,\N,TSPEAR
507915,21:45995070:G>A,NM_198687.2:c.*229G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,2.117,0.002,1KG_EAS_AF,TSPEAR
507916,21:45995076:C>T,NM_198687.2:c.*235C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,2.847,0.001,1KG_EAS_AF|1KG_EUR_AF,TSPEAR
507917,21:45995110:C>G,NM_198687.2:c.*269C>G,\N,1/1,\N,Benign,\N,3_prime_UTR_variant,3.372,0.0356,1KG_AFR_AF,TSPEAR
507918,21:45995127:C>A,NM_198687.2:c.*286C>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,5.482,0.0023,1KG_AFR_AF,TSPEAR
507919,21:45995127:C>T,NM_198687.2:c.*286C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,5.103,\N,\N,TSPEAR
507920,21:45995141:C>T,NM_144991.2:c.83-7252G>A,\N,\N,1/11,Benign,\N,intron_variant,5.845,0.2345,1KG_AFR_AF,TSPEAR
507921,21:45995146:C>T,NM_198687.2:c.*305C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,6.038,\N,\N,TSPEAR
507922,21:45995150:G>A,NM_198687.2:c.*309G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,3.316,0.001,1KG_EAS_AF,TSPEAR
507923,21:45995151:A>C,NM_198687.2:c.*310A>C,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,1.22,0.001,1KG_EUR_AF,TSPEAR
507924,21:45995154:C>T,NM_198687.2:c.*313C>T,\N,1/1,\N,Benign,\N,3_prime_UTR_variant,6.848,0.513,1KG_AMR_AF,TSPEAR
507925,21:45995155:G>A,NM_198687.2:c.*314G>A,\N,1/1,\N,Benign,\N,3_prime_UTR_variant,0.663,0.1778,1KG_AFR_AF,TSPEAR
507926,21:45995164:C>G,NM_198687.2:c.*323C>G,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,3.294,0.001,1KG_EUR_AF,TSPEAR
507927,21:45995186:C>T,NM_198687.2:c.*345C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,3.079,\N,\N,TSPEAR
507928,21:45995188:G>A,NM_198687.2:c.*347G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,1.826,\N,\N,TSPEAR
507929,21:45995203:G>A,NM_198687.2:c.*362G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,4.975,0.0008,1KG_AFR_AF,TSPEAR
507930,21:45995208:C>G,NM_198687.2:c.*367C>G,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,1.125,\N,\N,TSPEAR
507931,21:45995220:T>A,NM_198687.2:c.*379T>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,9.415,\N,\N,TSPEAR
507932,21:45995222:A>G,NM_198687.2:c.*381A>G,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,6.25,\N,\N,TSPEAR
507933,21:45995252:C>A,NM_144991.2:c.83-7363G>T,\N,\N,1/11,Unknown significance,\N,intron_variant,6.19,0.0014,1KG_AMR_AF,TSPEAR
507934,21:45995277:C>A,NM_144991.2:c.83-7388G>T,\N,\N,1/11,Unknown significance,\N,intron_variant,5.198,0.001,1KG_SAS_AF,TSPEAR
507935,21:45995287:C>T,NM_144991.2:c.83-7398G>A,\N,\N,1/11,Benign,\N,intron_variant,0.828,0.1528,1KG_AFR_AF,TSPEAR
507936,21:45995293:T>C,NM_144991.2:c.83-7404A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,2.636,0.003,1KG_AFR_AF,TSPEAR
507937,21:45995315:C>A,NM_144991.2:c.83-7426G>T,\N,\N,1/11,Unknown significance,\N,intron_variant,6.229,0.001,1KG_SAS_AF,TSPEAR
507938,21:45995333:G>T,NM_144991.2:c.83-7444C>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.094,\N,\N,TSPEAR
507939,21:45995338:T>C,NM_144991.2:c.83-7449A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,1.051,0.0014,1KG_AMR_AF,TSPEAR
507940,21:45995340:A>G,NM_144991.2:c.83-7451T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,1.804,0.0008,1KG_AFR_AF,TSPEAR
507941,21:45995362:C>T,NM_144991.2:c.83-7473G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.517,\N,\N,TSPEAR
507942,21:45995363:G>A,NM_144991.2:c.83-7474C>T,\N,\N,1/11,Benign,\N,intron_variant,2.747,0.0469,1KG_AFR_AF,TSPEAR
507943,21:45995364:T>C,NM_144991.2:c.83-7475A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,1.048,0.0014,1KG_AMR_AF,TSPEAR
507944,21:45995378:G>A,NM_144991.2:c.83-7489C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,4.682,0.001,1KG_EUR_AF,TSPEAR
507945,21:45995391:G>A,NM_144991.2:c.83-7502C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.836,\N,\N,TSPEAR
507946,21:45995402:C>A,NM_144991.2:c.83-7513G>T,\N,\N,1/11,Benign,\N,intron_variant,3.255,0.0113,1KG_AFR_AF,TSPEAR
507947,21:45995402:C>T,NM_144991.2:c.83-7513G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,2.532,0.002,1KG_EAS_AF,TSPEAR
507948,21:45995414:C>G,NM_144991.2:c.83-7525G>C,\N,\N,1/11,Unknown significance,\N,intron_variant,3.527,0.0014,1KG_AMR_AF,TSPEAR
507949,21:45995456:C>G,NM_144991.2:c.83-7567G>C,\N,\N,1/11,Unknown significance,\N,intron_variant,4.517,0.0015,1KG_AFR_AF,TSPEAR
507950,21:45995478:A>G,NM_144991.2:c.83-7589T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,3.102,\N,\N,TSPEAR
507951,21:45995607:GT>G,NM_144991.2:c.83-7719del,\N,\N,1/11,Benign,\N,intron_variant,0.544,0.0068,1KG_AFR_AF,TSPEAR
507952,21:45995618:C>T,NM_144991.2:c.83-7729G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,1.241,\N,\N,TSPEAR
507953,21:45995619:G>A,NM_144991.2:c.83-7730C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.044,0.001,1KG_EAS_AF,TSPEAR
507954,21:45995663:G>A,NM_144991.2:c.83-7774C>T,\N,\N,1/11,Benign,\N,intron_variant,0.895,0.2337,1KG_AFR_AF,TSPEAR
507955,21:45995686:C>T,NM_144991.2:c.83-7797G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,2.26,0.0008,1KG_AFR_AF,TSPEAR
507956,21:45995687:G>T,NM_144991.2:c.83-7798C>A,\N,\N,1/11,Unknown significance,\N,intron_variant,1.57,\N,\N,TSPEAR
507957,21:45995695:T>C,NM_144991.2:c.83-7806A>G,\N,\N,1/11,Benign,\N,intron_variant,2.252,0.0159,1KG_AMR_AF,TSPEAR
507958,21:45995699:G>T,NM_144991.2:c.83-7810C>A,\N,\N,1/11,Benign,\N,intron_variant,4.742,0.0537,1KG_AFR_AF,TSPEAR
507959,21:45995713:G>A,NM_144991.2:c.83-7824C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,4.097,0.001,1KG_EAS_AF|1KG_EUR_AF,TSPEAR
507960,21:45995733:G>A,NM_144991.2:c.83-7844C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,8.853,\N,\N,TSPEAR
507961,21:45995753:C>T,NM_144991.2:c.83-7864G>A,\N,\N,1/11,Benign,\N,intron_variant,1.057,0.0079,1KG_EAS_AF,TSPEAR
507962,21:45995755:G>C,NM_144991.2:c.83-7866C>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.882,0.0008,1KG_AFR_AF,TSPEAR
507963,21:45995756:CCTCT>C,NM_144991.2:c.83-7871_83-7868del,\N,\N,1/11,Benign,\N,intron_variant,5.252,0.0169,1KG_EUR_AF,TSPEAR
507964,21:45995757:C>T,NM_144991.2:c.83-7868G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,2.595,0.0014,1KG_AMR_AF,TSPEAR
507965,21:45995776:T>C,NM_144991.2:c.83-7887A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,4.207,0.002,1KG_EAS_AF,TSPEAR
507966,21:45995817:CGACA>C,NM_144991.2:c.83-7932_83-7929del,\N,\N,1/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
507967,21:45995818:G>A,NM_144991.2:c.83-7929C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.409,0.0008,1KG_AFR_AF,TSPEAR
507968,21:45995831:C>T,NM_144991.2:c.83-7942G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,2.798,\N,\N,TSPEAR
507969,21:45995843:A>C,NM_144991.2:c.83-7954T>G,\N,\N,1/11,Unknown significance,\N,intron_variant,1.88,0.002,1KG_SAS_AF,TSPEAR
507970,21:45995859:C>T,NM_144991.2:c.83-7970G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.029,0.0008,1KG_AFR_AF,TSPEAR
507971,21:45995860:G>A,NM_144991.2:c.83-7971C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.599,0.0023,1KG_AFR_AF,TSPEAR
507972,21:45995862:A>G,NM_144991.2:c.83-7973T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,0.564,\N,\N,TSPEAR
507973,21:45995864:T>C,NM_144991.2:c.83-7975A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.962,\N,\N,TSPEAR
507974,21:45995867:C>T,NM_144991.2:c.83-7978G>A,\N,\N,1/11,Benign,\N,intron_variant,4.364,0.0092,1KG_SAS_AF,TSPEAR
507975,21:45995887:G>A,NM_144991.2:c.83-7998C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.801,0.0008,1KG_AFR_AF,TSPEAR
507976,21:45995898:A>C,NM_144991.2:c.83-8009T>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.708,\N,\N,TSPEAR
507977,21:45995938:G>A,NM_144991.2:c.83-8049C>T,\N,\N,1/11,Benign,\N,intron_variant,8.128,0.006,1KG_EAS_AF,TSPEAR
507978,21:45995969:T>C,NM_144991.2:c.83-8080A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,2.314,0.003,1KG_AFR_AF,TSPEAR
507979,21:45995974:A>G,NM_144991.2:c.83-8085T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,4.231,0.001,1KG_EAS_AF,TSPEAR
507980,21:45995985:A>G,NM_144991.2:c.83-8096T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,4.053,\N,\N,TSPEAR
507981,21:45996029:T>C,NM_144991.2:c.83-8140A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,3.42,\N,\N,TSPEAR
507982,21:45996033:T>C,NM_144991.2:c.83-8144A>G,\N,\N,1/11,Benign,\N,intron_variant,2.798,0.4796,1KG_AFR_AF,TSPEAR
507983,21:45996052:C>T,NM_144991.2:c.83-8163G>A,\N,\N,1/11,Benign,\N,intron_variant,0.159,0.0287,1KG_AFR_AF,TSPEAR
507984,21:45996053:G>A,NM_144991.2:c.83-8164C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.401,0.001,1KG_EAS_AF,TSPEAR
507985,21:45996064:C>T,NM_144991.2:c.83-8175G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,3.323,\N,\N,TSPEAR
507986,21:45996065:G>A,NM_144991.2:c.83-8176C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,2.323,\N,\N,TSPEAR
507987,21:45996074:G>A,NM_144991.2:c.83-8185C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.606,\N,\N,TSPEAR
507988,21:45996100:C>T,NM_144991.2:c.83-8211G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,6.831,0.001,1KG_SAS_AF,TSPEAR
507989,21:45996111:C>T,NM_144991.2:c.83-8222G>A,\N,\N,1/11,Benign,\N,intron_variant,0.267,0.0706,1KG_AMR_AF,TSPEAR
507990,21:45996112:G>A,NM_144991.2:c.83-8223C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.135,0.001,1KG_SAS_AF,TSPEAR
507991,21:45996137:G>C,NM_144991.2:c.83-8248C>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.992,\N,\N,TSPEAR
507992,21:45996154:G>A,NM_144991.2:c.83-8265C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.279,0.0008,1KG_AFR_AF,TSPEAR
507993,21:45996171:T>C,NM_144991.2:c.83-8282A>G,\N,\N,1/11,Benign,\N,intron_variant,0.396,0.0938,1KG_AFR_AF,TSPEAR
507994,21:45996173:T>A,NM_144991.2:c.83-8284A>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.88,\N,\N,TSPEAR
507995,21:45996180:G>A,NM_144991.2:c.83-8291C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.815,0.0008,1KG_AFR_AF,TSPEAR
507996,21:45996197:A>C,NM_144991.2:c.83-8308T>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.034,\N,\N,TSPEAR
507997,21:45996218:C>T,NM_144991.2:c.83-8329G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,3.035,0.002,1KG_SAS_AF,TSPEAR
507998,21:45996219:G>A,NM_144991.2:c.83-8330C>T,\N,\N,1/11,Benign,\N,intron_variant,0.725,0.006,1KG_EUR_AF,TSPEAR
507999,21:45996223:G>A,NM_144991.2:c.83-8334C>T,\N,\N,1/11,Benign,\N,intron_variant,0.34,0.0507,1KG_AFR_AF,TSPEAR
508000,21:45996264:A>C,NM_144991.2:c.83-8375T>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.512,0.001,1KG_SAS_AF,TSPEAR
508001,21:45996321:G>A,NM_144991.2:c.83-8432C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,2.324,0.0023,1KG_AFR_AF,TSPEAR
508002,21:45996371:T>C,NM_144991.2:c.83-8482A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,1.328,\N,\N,TSPEAR
508003,21:45996375:T>C,NM_144991.2:c.83-8486A>G,\N,\N,1/11,Benign,\N,intron_variant,1.254,0.0764,1KG_AFR_AF,TSPEAR
508004,21:45996379:C>T,NM_144991.2:c.83-8490G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,5.74,0.0014,1KG_AMR_AF,TSPEAR
508005,21:45996393:G>A,NM_144991.2:c.83-8504C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,2.523,0.003,1KG_AFR_AF,TSPEAR
508006,21:45996396:G>A,NM_144991.2:c.83-8507C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,2.3,\N,\N,TSPEAR
508007,21:45996416:T>G,NM_144991.2:c.83-8527A>C,\N,\N,1/11,Benign,\N,intron_variant,3.242,0.0089,1KG_EUR_AF,TSPEAR
508008,21:45996417:G>A,NM_144991.2:c.83-8528C>T,\N,\N,1/11,Benign,\N,intron_variant,4.09,0.0089,1KG_EUR_AF,TSPEAR
508009,21:45996419:C>A,NM_144991.2:c.83-8530G>T,\N,\N,1/11,Benign,\N,intron_variant,4.107,0.0089,1KG_EUR_AF,TSPEAR
508010,21:45996438:A>T,NM_144991.2:c.83-8549T>A,\N,\N,1/11,Unknown significance,\N,intron_variant,1.471,\N,\N,TSPEAR
508011,21:45996455:G>A,NM_144991.2:c.83-8566C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.456,0.001,1KG_EUR_AF,TSPEAR
508012,21:45996457:A>C,NM_144991.2:c.83-8568T>G,\N,\N,1/11,Benign,\N,intron_variant,1.96,0.149,1KG_AFR_AF,TSPEAR
508013,21:45996474:A>G,NM_144991.2:c.83-8585T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,1.477,\N,\N,TSPEAR
508014,21:45996487:T>G,NM_144991.2:c.83-8598A>C,\N,\N,1/11,Unknown significance,\N,intron_variant,5.036,0.001,1KG_EUR_AF,TSPEAR
508015,21:45996498:G>T,NM_144991.2:c.83-8609C>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.606,0.002,1KG_EAS_AF,TSPEAR
508016,21:45996511:G>C,NM_144991.2:c.83-8622C>G,\N,\N,1/11,Unknown significance,\N,intron_variant,1.082,\N,\N,TSPEAR
508017,21:45996512:A>G,NM_144991.2:c.83-8623T>C,\N,\N,1/11,Benign,\N,intron_variant,1.376,0.0219,1KG_AFR_AF,TSPEAR
508018,21:45996530:G>A,NM_144991.2:c.83-8641C>T,\N,\N,1/11,Benign,\N,intron_variant,6.885,0.0227,1KG_AFR_AF,TSPEAR
508019,21:45996535:G>A,NM_144991.2:c.83-8646C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.204,0.001,1KG_EAS_AF,TSPEAR
508020,21:45996546:C>T,NM_144991.2:c.83-8657G>A,\N,\N,1/11,Benign,\N,intron_variant,0.993,0.0363,1KG_AFR_AF,TSPEAR
508021,21:45996566:G>C,NM_144991.2:c.83-8677C>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.942,0.001,1KG_SAS_AF,TSPEAR
508022,21:45996600:T>C,NM_144991.2:c.83-8711A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,2.307,\N,\N,TSPEAR
508023,21:45996601:C>G,NM_144991.2:c.83-8712G>C,\N,\N,1/11,Unknown significance,\N,intron_variant,0.96,\N,\N,TSPEAR
508024,21:45996667:G>A,NM_144991.2:c.83-8778C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.289,\N,\N,TSPEAR
508025,21:45996702:A>T,NM_144991.2:c.83-8813T>A,\N,\N,1/11,Benign,\N,intron_variant,0.9,0.0053,1KG_AFR_AF,TSPEAR
508026,21:45996707:T>G,NM_144991.2:c.83-8818A>C,\N,\N,1/11,Unknown significance,\N,intron_variant,0.831,\N,\N,TSPEAR
508027,21:45996717:G>A,NM_144991.2:c.83-8828C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.446,0.001,1KG_EUR_AF,TSPEAR
508028,21:45996733:G>A,NM_144991.2:c.83-8844C>T,\N,\N,1/11,Benign,\N,intron_variant,2.15,0.0393,1KG_AFR_AF,TSPEAR
508029,21:45996759:C>T,NM_144991.2:c.83-8870G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.044,\N,\N,TSPEAR
508030,21:45996760:G>A,NM_144991.2:c.83-8871C>T,\N,\N,1/11,Benign,\N,intron_variant,2.264,0.0086,1KG_AMR_AF,TSPEAR
508031,21:45996777:A>C,NM_144991.2:c.83-8888T>G,\N,\N,1/11,Unknown significance,\N,intron_variant,1.46,\N,\N,TSPEAR
508032,21:45996785:T>A,NM_144991.2:c.83-8896A>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.103,\N,\N,TSPEAR
508033,21:45996832:G>T,NM_144991.2:c.83-8943C>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.55,0.0008,1KG_AFR_AF,TSPEAR
508034,21:45996863:G>A,NM_144991.2:c.83-8974C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,12.24,0.0038,1KG_AFR_AF,TSPEAR
508035,21:45996869:T>C,NM_144991.2:c.83-8980A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,9.781,0.0008,1KG_AFR_AF,TSPEAR
508036,21:45996885:A>C,NM_144991.2:c.83-8996T>G,\N,\N,1/11,Unknown significance,\N,intron_variant,6.642,0.0014,1KG_AMR_AF,TSPEAR
508037,21:45996915:C>A,NM_144991.2:c.83-9026G>T,\N,\N,1/11,Unknown significance,\N,intron_variant,7.191,0.0008,1KG_AFR_AF,TSPEAR
508038,21:45996923:A>G,NM_144991.2:c.83-9034T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,7.628,0.0031,1KG_SAS_AF,TSPEAR
508039,21:45996960:G>C,NM_144991.2:c.83-9071C>G,\N,\N,1/11,Unknown significance,\N,intron_variant,1.154,0.001,1KG_EUR_AF,TSPEAR
508040,21:45997027:G>A,NM_144991.2:c.83-9138C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,10.31,0.001,1KG_EUR_AF,TSPEAR
508041,21:45997080:C>T,NM_144991.2:c.83-9191G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.087,0.002,1KG_EUR_AF,TSPEAR
508042,21:45997081:G>A,NM_144991.2:c.83-9192C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.925,\N,\N,TSPEAR
508043,21:45997084:C>A,NM_144991.2:c.83-9195G>T,\N,\N,1/11,Benign,\N,intron_variant,2.671,0.1089,1KG_AFR_AF,TSPEAR
508044,21:45997085:T>C,NM_144991.2:c.83-9196A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.811,\N,\N,TSPEAR
508045,21:45997127:A>T,NM_144991.2:c.83-9238T>A,\N,\N,1/11,Benign,\N,intron_variant,0.402,0.0938,1KG_AFR_AF,TSPEAR
508046,21:45997133:A>G,NM_144991.2:c.83-9244T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,2.569,0.001,1KG_EUR_AF,TSPEAR
508047,21:45997138:T>C,NM_144991.2:c.83-9249A>G,\N,\N,1/11,Benign,\N,intron_variant,2.075,0.0182,1KG_AFR_AF,TSPEAR
508048,21:45997142:A>G,NM_144991.2:c.83-9253T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,0.934,0.0031,1KG_SAS_AF,TSPEAR
508049,21:45997149:T>C,NM_144991.2:c.83-9260A>G,\N,\N,1/11,Benign,\N,intron_variant,2.066,0.0272,1KG_AFR_AF,TSPEAR
508050,21:45997153:G>C,NM_144991.2:c.83-9264C>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.021,0.0029,1KG_AMR_AF,TSPEAR
508051,21:45997153:GA>G,NM_144991.2:c.83-9265del,\N,\N,1/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
508052,21:45997191:G>A,NM_144991.2:c.83-9302C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.558,0.0008,1KG_AFR_AF,TSPEAR
508053,21:45997199:G>A,NM_144991.2:c.83-9310C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.214,0.0014,1KG_AMR_AF,TSPEAR
508054,21:45997224:T>C,NM_144991.2:c.83-9335A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,1.515,\N,\N,TSPEAR
508055,21:45997225:G>A,NM_144991.2:c.83-9336C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.322,\N,\N,TSPEAR
508056,21:45997239:G>A,NM_144991.2:c.83-9350C>T,\N,\N,1/11,Benign,\N,intron_variant,0.021,0.0189,1KG_EUR_AF,TSPEAR
508057,21:45997258:C>T,NM_144991.2:c.83-9369G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,6.82,0.001,1KG_EAS_AF,TSPEAR
508058,21:45997274:C>A,NM_144991.2:c.83-9385G>T,\N,\N,1/11,Benign,\N,intron_variant,9.373,0.233,1KG_AFR_AF,TSPEAR
508059,21:45997316:A>G,NM_144991.2:c.83-9427T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,2.914,0.0008,1KG_AFR_AF,TSPEAR
508060,21:45997319:C>T,NM_144991.2:c.83-9430G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.125,0.0015,1KG_AFR_AF,TSPEAR
508061,21:45997335:C>T,NM_144991.2:c.83-9446G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.862,0.0008,1KG_AFR_AF,TSPEAR
508062,21:45997336:G>A,NM_144991.2:c.83-9447C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,2.629,0.0008,1KG_AFR_AF,TSPEAR
508063,21:45997380:G>A,NM_144991.2:c.83-9491C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,5.453,\N,\N,TSPEAR
508064,21:45997387:G>T,NM_144991.2:c.83-9498C>A,\N,\N,1/11,Unknown significance,\N,intron_variant,2.627,\N,\N,TSPEAR
508065,21:45997397:C>T,NM_144991.2:c.83-9508G>A,\N,\N,1/11,Benign,\N,intron_variant,3.468,0.0098,1KG_AFR_AF,TSPEAR
508066,21:45997399:C>T,NM_144991.2:c.83-9510G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,2.997,\N,\N,TSPEAR
508067,21:45997428:A>G,NM_144991.2:c.83-9539T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,2.586,\N,\N,TSPEAR
508068,21:45997447:A>G,NM_144991.2:c.83-9558T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,2.531,\N,\N,TSPEAR
508069,21:45997487:G>A,NM_144991.2:c.83-9598C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.032,\N,\N,TSPEAR
508070,21:45997529:C>T,NM_144991.2:c.83-9640G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,3.516,0.001,1KG_EUR_AF,TSPEAR
508071,21:45997531:C>G,NM_144991.2:c.83-9642G>C,\N,\N,1/11,Benign,\N,intron_variant,1.775,0.0089,1KG_EUR_AF,TSPEAR
508072,21:45997560:G>A,NM_144991.2:c.83-9671C>T,\N,\N,1/11,Benign,\N,intron_variant,10.9,0.0575,1KG_AFR_AF,TSPEAR
508073,21:45997565:C>A,NM_144991.2:c.83-9676G>T,\N,\N,1/11,Unknown significance,\N,intron_variant,11.19,0.0008,1KG_AFR_AF,TSPEAR
508074,21:45997573:C>A,NM_144991.2:c.83-9684G>T,\N,\N,1/11,Benign,\N,intron_variant,10.65,0.0219,1KG_EUR_AF,TSPEAR
508075,21:45997576:C>T,NM_144991.2:c.83-9687G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,10.49,\N,\N,TSPEAR
508076,21:45997624:C>A,NM_144991.2:c.83-9735G>T,\N,\N,1/11,Unknown significance,\N,intron_variant,7.189,\N,\N,TSPEAR
508077,21:45997624:C>T,NM_144991.2:c.83-9735G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,5.943,0.002,1KG_EAS_AF,TSPEAR
508078,21:45997630:C>T,NM_144991.2:c.83-9741G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,6.083,0.001,1KG_EAS_AF,TSPEAR
508079,21:45997633:G>C,NM_144991.2:c.83-9744C>G,\N,\N,1/11,Unknown significance,\N,intron_variant,1.424,\N,\N,TSPEAR
508080,21:45997650:T>C,NM_144991.2:c.83-9761A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.144,\N,\N,TSPEAR
508081,21:45997676:T>C,NM_144991.2:c.83-9787A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,4.647,\N,\N,TSPEAR
508082,21:45997689:A>G,NM_144991.2:c.83-9800T>C,\N,\N,1/11,Benign,\N,intron_variant,5.823,0.0061,1KG_AFR_AF,TSPEAR
508083,21:45997701:A>G,NM_144991.2:c.83-9812T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,4.168,0.0008,1KG_AFR_AF,TSPEAR
508084,21:45997716:C>T,NM_144991.2:c.83-9827G>A,\N,\N,1/11,Benign,\N,intron_variant,0.027,0.0371,1KG_AFR_AF,TSPEAR
508085,21:45997717:G>A,NM_144991.2:c.83-9828C>T,\N,\N,1/11,Benign,\N,intron_variant,0.143,0.0068,1KG_AFR_AF,TSPEAR
508086,21:45997728:T>G,NM_144991.2:c.83-9839A>C,\N,\N,1/11,Unknown significance,\N,intron_variant,3.196,0.001,1KG_EUR_AF,TSPEAR
508087,21:45997769:A>G,NM_144991.2:c.83-9880T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,0.204,0.001,1KG_SAS_AF,TSPEAR
508088,21:45997801:G>A,NM_144991.2:c.83-9912C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.896,0.001,1KG_SAS_AF,TSPEAR
508089,21:45997804:T>C,NM_144991.2:c.83-9915A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,1.906,\N,\N,TSPEAR
508090,21:45997825:G>A,NM_144991.2:c.83-9936C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.276,\N,\N,TSPEAR
508091,21:45997840:T>C,NM_144991.2:c.83-9951A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,2.805,\N,\N,TSPEAR
508092,21:45997846:A>G,NM_144991.2:c.83-9957T>C,\N,\N,1/11,Benign,\N,intron_variant,2.68,0.2004,1KG_EAS_AF,TSPEAR
508093,21:45997868:G>A,NM_144991.2:c.83-9979C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,2.194,0.0029,1KG_AMR_AF,TSPEAR
508094,21:45997886:T>TC,NM_144991.2:c.83-9998dup,\N,\N,1/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
508095,21:45997894:C>T,NM_144991.2:c.83-10005G>A,\N,\N,1/11,Benign,\N,intron_variant,2.782,0.0091,1KG_AFR_AF,TSPEAR
508096,21:45997964:C>T,NM_144991.2:c.83-10075G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,6.119,0.003,1KG_EAS_AF,TSPEAR
508097,21:45997965:C>T,NM_144991.2:c.83-10076G>A,\N,\N,1/11,Benign,\N,intron_variant,6.01,0.2014,1KG_EAS_AF,TSPEAR
508098,21:45997975:G>A,NM_144991.2:c.83-10086C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.853,\N,\N,TSPEAR
508099,21:45997989:A>G,NM_144991.2:c.83-10100T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,4.339,0.001,1KG_SAS_AF,TSPEAR
508100,21:45997992:A>G,NM_144991.2:c.83-10103T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,3.699,0.001,1KG_EUR_AF,TSPEAR
508101,21:45997995:C>A,NM_144991.2:c.83-10106G>T,\N,\N,1/11,Benign,\N,intron_variant,6.273,0.0051,1KG_SAS_AF,TSPEAR
508102,21:45997996:CTCTT>C,NM_144991.2:c.83-10111_83-10108del,\N,\N,1/11,Unknown significance,\N,intron_variant,5.358,\N,\N,TSPEAR
508103,21:45998025:G>C,NM_144991.2:c.83-10136C>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.727,\N,\N,TSPEAR
508104,21:45998027:T>A,NM_144991.2:c.83-10138A>T,\N,\N,1/11,Benign,\N,intron_variant,4.752,0.2012,1KG_AFR_AF,TSPEAR
508105,21:45998043:C>A,NM_144991.2:c.83-10154G>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.404,\N,\N,TSPEAR
508106,21:45998044:C>T,NM_144991.2:c.83-10155G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,1.883,\N,\N,TSPEAR
508107,21:45998045:G>A,NM_144991.2:c.83-10156C>T,\N,\N,1/11,Benign,\N,intron_variant,0.011,0.2014,1KG_EAS_AF,TSPEAR
508108,21:45998062:C>T,NM_144991.2:c.83-10173G>A,\N,\N,1/11,Benign,\N,intron_variant,0.407,0.0333,1KG_AFR_AF,TSPEAR
508109,21:45998063:A>C,NM_144991.2:c.83-10174T>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.491,0.0008,1KG_AFR_AF,TSPEAR
508110,21:45998077:A>G,NM_144991.2:c.83-10188T>C,\N,\N,1/11,Benign,\N,intron_variant,2.06,0.0537,1KG_AFR_AF,TSPEAR
508111,21:45998078:A>C,NM_144991.2:c.83-10189T>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.408,\N,\N,TSPEAR
508112,21:45998080:G>C,NM_144991.2:c.83-10191C>G,\N,\N,1/11,Benign,\N,intron_variant,0.352,0.0053,1KG_AFR_AF,TSPEAR
508113,21:45998080:G>T,NM_144991.2:c.83-10191C>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.7,\N,\N,TSPEAR
508114,21:45998098:T>G,NM_144991.2:c.83-10209A>C,\N,\N,1/11,Unknown significance,\N,intron_variant,1.793,0.0008,1KG_AFR_AF,TSPEAR
508115,21:45998113:G>C,NM_144991.2:c.83-10224C>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.239,0.0008,1KG_AFR_AF,TSPEAR
508116,21:45998122:CAAAT>C,NM_144991.2:c.83-10237_83-10234del,\N,\N,1/11,Benign,\N,intron_variant,6.126,0.0673,1KG_AFR_AF,TSPEAR
508117,21:45998136:A>C,NM_144991.2:c.83-10247T>G,\N,\N,1/11,Benign,\N,intron_variant,0.327,0.006,1KG_EUR_AF,TSPEAR
508118,21:45998138:C>T,NM_144991.2:c.83-10249G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.721,0.001,1KG_SAS_AF,TSPEAR
508119,21:45998156:A>G,NM_144991.2:c.83-10267T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,6.171,0.0008,1KG_AFR_AF,TSPEAR
508120,21:45998161:C>T,NM_144991.2:c.83-10272G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,5.551,\N,\N,TSPEAR
508121,21:45998165:G>C,NM_144991.2:c.83-10276C>G,\N,\N,1/11,Unknown significance,\N,intron_variant,1.609,0.001,1KG_SAS_AF,TSPEAR
508122,21:45998175:G>A,NM_144991.2:c.83-10286C>T,\N,\N,1/11,Benign,\N,intron_variant,4.459,0.007,1KG_EUR_AF,TSPEAR
508123,21:45998188:A>C,NM_144991.2:c.83-10299T>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.64,\N,\N,TSPEAR
508124,21:45998225:G>A,NM_144991.2:c.83-10336C>T,\N,\N,1/11,Benign,\N,intron_variant,6.096,0.0149,1KG_EAS_AF,TSPEAR
508125,21:45998232:T>G,NM_144991.2:c.83-10343A>C,\N,\N,1/11,Benign,\N,intron_variant,4.142,0.1944,1KG_EAS_AF,TSPEAR
508126,21:45998288:G>C,NM_144991.2:c.83-10399C>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.025,0.001,1KG_SAS_AF,TSPEAR
508127,21:45998292:C>G,NM_144991.2:c.83-10403G>C,\N,\N,1/11,Unknown significance,\N,intron_variant,0.241,0.001,1KG_EAS_AF|1KG_SAS_AF,TSPEAR
508128,21:45998310:G>A,NM_144991.2:c.83-10421C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.171,0.001,1KG_EUR_AF,TSPEAR
508129,21:45998311:C>T,NM_144991.2:c.83-10422G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,4.974,0.001,1KG_EUR_AF,TSPEAR
508130,21:45998313:T>C,NM_144991.2:c.83-10424A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,2.914,0.0014,1KG_AMR_AF,TSPEAR
508131,21:45998317:T>C,NM_144991.2:c.83-10428A>G,\N,\N,1/11,Benign,\N,intron_variant,3.786,0.1944,1KG_EAS_AF,TSPEAR
508132,21:45998328:A>G,NM_144991.2:c.83-10439T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,6.257,\N,\N,TSPEAR
508133,21:45998357:A>G,NM_144991.2:c.83-10468T>C,\N,\N,1/11,Benign,\N,intron_variant,2.657,0.0143,1KG_SAS_AF,TSPEAR
508134,21:45998367:A>G,NM_144991.2:c.83-10478T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,0.444,0.001,1KG_EAS_AF,TSPEAR
508135,21:45998402:C>T,NM_144991.2:c.83-10513G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.087,0.0014,1KG_AMR_AF,TSPEAR
508136,21:45998403:G>A,NM_144991.2:c.83-10514C>T,\N,\N,1/11,Benign,\N,intron_variant,3.918,0.025,1KG_AFR_AF,TSPEAR
508137,21:45998405:C>T,NM_144991.2:c.83-10516G>A,\N,\N,1/11,Benign,\N,intron_variant,0.368,0.0123,1KG_SAS_AF,TSPEAR
508138,21:45998406:G>A,NM_144991.2:c.83-10517C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.96,0.001,1KG_EAS_AF,TSPEAR
508139,21:45998408:G>A,NM_144991.2:c.83-10519C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.569,0.002,1KG_EUR_AF,TSPEAR
508140,21:45998409:C>G,NM_144991.2:c.83-10520G>C,\N,\N,1/11,Benign,\N,intron_variant,4.099,0.1944,1KG_EAS_AF,TSPEAR
508141,21:45998416:G>C,NM_144991.2:c.83-10527C>G,\N,\N,1/11,Benign,\N,intron_variant,1.654,0.0202,1KG_AMR_AF,TSPEAR
508142,21:45998429:G>A,NM_144991.2:c.83-10540C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,2.101,0.0015,1KG_AFR_AF,TSPEAR
508143,21:45998446:G>A,NM_144991.2:c.83-10557C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,6.696,\N,\N,TSPEAR
508144,21:45998458:C>T,NM_144991.2:c.83-10569G>A,\N,\N,1/11,Benign,\N,intron_variant,1.32,0.1944,1KG_EAS_AF,TSPEAR
508145,21:45998515:G>A,NM_144991.2:c.83-10626C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,4.475,0.001,1KG_SAS_AF,TSPEAR
508146,21:45998516:G>A,NM_144991.2:c.83-10627C>T,\N,\N,1/11,Benign,\N,intron_variant,0.947,0.0295,1KG_AFR_AF,TSPEAR
508147,21:45998524:G>C,NM_144991.2:c.83-10635C>G,\N,\N,1/11,Benign,\N,intron_variant,0.168,0.1944,1KG_EAS_AF,TSPEAR
508148,21:45998528:C>T,NM_144991.2:c.83-10639G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.183,0.0038,1KG_AFR_AF,TSPEAR
508149,21:45998534:G>A,NM_144991.2:c.83-10645C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,5.156,0.0023,1KG_AFR_AF,TSPEAR
508150,21:45998551:G>C,NM_144991.2:c.83-10662C>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.464,\N,\N,TSPEAR
508151,21:45998564:C>A,NM_144991.2:c.83-10675G>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.009,\N,\N,TSPEAR
508152,21:45998618:C>T,NM_144991.2:c.83-10729G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,4.933,\N,\N,TSPEAR
508153,21:45998623:G>A,NM_144991.2:c.83-10734C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.155,\N,\N,TSPEAR
508154,21:45998664:C>G,NM_144991.2:c.83-10775G>C,\N,\N,1/11,Benign,\N,intron_variant,2.199,0.0635,1KG_AFR_AF,TSPEAR
508155,21:45998672:G>T,NM_144991.2:c.83-10783C>A,\N,\N,1/11,Unknown significance,\N,intron_variant,1.677,\N,\N,TSPEAR
508156,21:45998711:A>G,NM_144991.2:c.83-10822T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,1.713,\N,\N,TSPEAR
508157,21:45998733:C>T,NM_144991.2:c.83-10844G>A,\N,\N,1/11,Benign,\N,intron_variant,0.095,0.005,1KG_EAS_AF,TSPEAR
508158,21:45998737:C>T,NM_144991.2:c.83-10848G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,6.089,0.0014,1KG_AMR_AF,TSPEAR
508159,21:45998751:C>T,NM_144991.2:c.83-10862G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,1.447,\N,\N,TSPEAR
508160,21:45998768:C>A,NM_144991.2:c.83-10879G>T,\N,\N,1/11,Benign,\N,intron_variant,2.633,0.2035,1KG_AFR_AF,TSPEAR
508161,21:45998775:T>C,NM_144991.2:c.83-10886A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.004,0.001,1KG_EAS_AF,TSPEAR
508162,21:45998777:C>T,NM_144991.2:c.83-10888G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.321,0.001,1KG_SAS_AF,TSPEAR
508163,21:45998824:G>A,NM_144991.2:c.83-10935C>T,\N,\N,1/11,Benign,\N,intron_variant,1.899,0.006,1KG_EAS_AF,TSPEAR
508164,21:45998831:A>C,NM_144991.2:c.83-10942T>G,\N,\N,1/11,Unknown significance,\N,intron_variant,1.736,0.0023,1KG_AFR_AF,TSPEAR
508165,21:45998837:A>C,NM_144991.2:c.83-10948T>G,\N,\N,1/11,Benign,\N,intron_variant,0.133,0.0106,1KG_AFR_AF,TSPEAR
508166,21:45998837:A>G,NM_144991.2:c.83-10948T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,0.508,\N,\N,TSPEAR
508167,21:45998873:C>T,NM_144991.2:c.83-10984G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.888,\N,\N,TSPEAR
508168,21:45998889:C>T,NM_144991.2:c.83-11000G>A,\N,\N,1/11,Benign,\N,intron_variant,1.267,0.1954,1KG_EAS_AF,TSPEAR
508169,21:45998890:G>A,NM_144991.2:c.83-11001C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.797,0.0008,1KG_AFR_AF,TSPEAR
508170,21:45998891:C>T,NM_144991.2:c.83-11002G>A,\N,\N,1/11,Benign,\N,intron_variant,0.007,0.0356,1KG_AFR_AF,TSPEAR
508171,21:45998892:G>T,NM_144991.2:c.83-11003C>A,\N,\N,1/11,Unknown significance,\N,intron_variant,2.321,0.001,1KG_SAS_AF,TSPEAR
508172,21:45998906:C>G,NM_144991.2:c.83-11017G>C,\N,\N,1/11,Unknown significance,\N,intron_variant,2.214,0.0008,1KG_AFR_AF,TSPEAR
508173,21:45998920:C>T,NM_144991.2:c.83-11031G>A,\N,\N,1/11,Benign,\N,intron_variant,0.587,0.0149,1KG_EAS_AF,TSPEAR
508174,21:45998927:GCTGCTGAA>G,NM_144991.2:c.83-11046_83-11039del,\N,\N,1/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
508175,21:45998931:C>A,NM_144991.2:c.83-11042G>T,\N,\N,1/11,Unknown significance,\N,intron_variant,5.73,0.0008,1KG_AFR_AF,TSPEAR
508176,21:45998932:TG>T,NM_144991.2:c.83-11044del,\N,\N,1/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
508177,21:45998933:G>A,NM_144991.2:c.83-11044C>T,\N,\N,1/11,Benign,\N,intron_variant,2.462,0.2027,1KG_AFR_AF,TSPEAR
508178,21:45998933:GAA>AAG,NM_144991.2:c.83-11046_83-11044delinsCTT,\N,\N,1/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
508179,21:45998935:A>G,NM_144991.2:c.83-11046T>C,\N,\N,1/11,Benign,\N,intron_variant,2.922,0.2027,1KG_AFR_AF,TSPEAR
508180,21:45998936:C>T,NM_144991.2:c.83-11047G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,3.143,\N,\N,TSPEAR
508181,21:45998937:G>A,NM_144991.2:c.83-11048C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.339,0.001,1KG_EAS_AF,TSPEAR
508182,21:45998946:C>T,NM_144991.2:c.83-11057G>A,\N,\N,1/11,Benign,\N,intron_variant,3.471,0.211,1KG_AFR_AF,TSPEAR
508183,21:45998949:C>T,NM_144991.2:c.83-11060G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.036,0.001,1KG_EAS_AF,TSPEAR
508184,21:45998953:C>T,NM_144991.2:c.83-11064G>A,\N,\N,1/11,Benign,\N,intron_variant,4.059,0.0109,1KG_EAS_AF,TSPEAR
508185,21:45998954:G>A,NM_144991.2:c.83-11065C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.275,\N,\N,TSPEAR
508186,21:45998981:C>A,NM_144991.2:c.83-11092G>T,\N,\N,1/11,Unknown significance,\N,intron_variant,6.535,\N,\N,TSPEAR
508187,21:45998992:T>C,NM_144991.2:c.83-11103A>G,\N,\N,1/11,Benign,\N,intron_variant,0.211,0.2035,1KG_AFR_AF,TSPEAR
508188,21:45998992:T>G,NM_144991.2:c.83-11103A>C,\N,\N,1/11,Unknown significance,\N,intron_variant,0.605,\N,\N,TSPEAR
508189,21:45998992:TA>CG,NM_144991.2:c.83-11104_83-11103delinsCG,\N,\N,1/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
508190,21:45998993:A>G,NM_144991.2:c.83-11104T>C,\N,\N,1/11,Benign,\N,intron_variant,0.409,0.9849,1KG_AFR_AF,TSPEAR
508191,21:45999000:G>A,NM_144991.2:c.83-11111C>T,\N,\N,1/11,Benign,\N,intron_variant,1.727,0.0805,1KG_EUR_AF,TSPEAR
508192,21:45999021:G>T,NM_144991.2:c.83-11132C>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.921,0.0014,1KG_AMR_AF,TSPEAR
508193,21:45999037:G>A,NM_144991.2:c.83-11148C>T,\N,\N,1/11,Benign,\N,intron_variant,3.919,0.0053,1KG_AFR_AF,TSPEAR
508194,21:45999062:G>A,NM_144991.2:c.83-11173C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,6.26,\N,\N,TSPEAR
508195,21:45999070:C>G,NM_144991.2:c.83-11181G>C,\N,\N,1/11,Unknown significance,\N,intron_variant,0.627,0.0014,1KG_AMR_AF,TSPEAR
508196,21:45999072:G>A,NM_144991.2:c.83-11183C>T,\N,\N,1/11,Benign,\N,intron_variant,3.576,0.0144,1KG_AMR_AF,TSPEAR
508197,21:45999075:C>A,NM_144991.2:c.83-11186G>T,\N,\N,1/11,Unknown significance,\N,intron_variant,4.92,0.0008,1KG_AFR_AF,TSPEAR
508198,21:45999085:G>A,NM_144991.2:c.83-11196C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.36,0.001,1KG_SAS_AF,TSPEAR
508199,21:45999108:G>A,NM_144991.2:c.83-11219C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.861,0.0041,1KG_SAS_AF,TSPEAR
508200,21:45999135:C>T,NM_144991.2:c.83-11246G>A,\N,\N,1/11,Benign,\N,intron_variant,4.932,0.0159,1KG_AFR_AF,TSPEAR
508201,21:45999142:A>G,NM_144991.2:c.83-11253T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,4.145,0.0014,1KG_AMR_AF,TSPEAR
508202,21:45999158:G>T,NM_144991.2:c.83-11269C>A,\N,\N,1/11,Unknown significance,\N,intron_variant,3.227,\N,\N,TSPEAR
508203,21:45999176:G>A,NM_144991.2:c.83-11287C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.682,0.003,1KG_AFR_AF,TSPEAR
508204,21:45999179:G>A,NM_144991.2:c.83-11290C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.552,\N,\N,TSPEAR
508205,21:45999223:G>A,NM_144991.2:c.83-11334C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,5.059,\N,\N,TSPEAR
508206,21:45999227:C>A,NM_144991.2:c.83-11338G>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.202,0.001,1KG_SAS_AF,TSPEAR
508207,21:45999242:T>C,NM_144991.2:c.83-11353A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,6.175,0.0043,1KG_AMR_AF,TSPEAR
508208,21:45999246:G>C,NM_144991.2:c.83-11357C>G,\N,\N,1/11,Unknown significance,\N,intron_variant,5.895,\N,\N,TSPEAR
508209,21:45999280:G>A,NM_144991.2:c.83-11391C>T,\N,\N,1/11,Benign,\N,intron_variant,1.673,0.0681,1KG_AFR_AF,TSPEAR
508210,21:45999280:G>C,NM_144991.2:c.83-11391C>G,\N,\N,1/11,Benign,\N,intron_variant,0.296,0.2526,1KG_AFR_AF,TSPEAR
508211,21:45999337:C>A,NM_198694.3:c.*303G>T,\N,1/1,\N,Benign,\N,3_prime_UTR_variant,3.073,0.0189,1KG_EUR_AF,TSPEAR
508212,21:45999337:C>T,NM_198694.3:c.*303G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,2.983,0.0023,1KG_AFR_AF,TSPEAR
508213,21:45999354:T>C,NM_198694.3:c.*286A>G,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,12.12,0.0023,1KG_AFR_AF,TSPEAR
508214,21:45999369:A>T,NM_198694.3:c.*271T>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,13.71,0.001,1KG_EAS_AF,TSPEAR
508215,21:45999371:G>C,NM_198694.3:c.*269C>G,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,12.25,0.001,1KG_EAS_AF,TSPEAR
508216,21:45999389:C>T,NM_198694.3:c.*251G>A,\N,1/1,\N,Benign,\N,3_prime_UTR_variant,4.108,0.0174,1KG_AFR_AF,TSPEAR
508217,21:45999390:G>A,NM_198694.3:c.*250C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,0.243,0.0015,1KG_AFR_AF,TSPEAR
508218,21:45999403:C>A,NM_144991.2:c.83-11514G>T,\N,\N,1/11,Benign,\N,intron_variant,5.566,0.1885,1KG_EAS_AF,TSPEAR
508219,21:45999408:G>A,NM_198694.3:c.*232C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,4.288,0.0045,1KG_AFR_AF,TSPEAR
508220,21:45999453:G>C,NM_198694.3:c.*187C>G,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,0.839,\N,\N,TSPEAR
508221,21:45999474:C>A,NM_198694.3:c.*166G>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,5.631,\N,\N,TSPEAR
508222,21:45999484:T>G,NM_198694.3:c.*156A>C,\N,1/1,\N,Benign,\N,3_prime_UTR_variant,2.196,0.1142,1KG_AFR_AF,TSPEAR
508223,21:45999485:C>T,NM_198694.3:c.*155G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,0.557,\N,\N,TSPEAR
508224,21:45999486:G>A,NM_198694.3:c.*154C>T,\N,1/1,\N,Benign,\N,3_prime_UTR_variant,1.3,0.0091,1KG_AFR_AF,TSPEAR
508225,21:45999497:T>C,NM_198694.3:c.*143A>G,\N,1/1,\N,Benign,\N,3_prime_UTR_variant,1.789,0.1142,1KG_AFR_AF,TSPEAR
508226,21:45999508:A>T,NM_198694.3:c.*132T>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,2.052,\N,\N,TSPEAR
508227,21:45999512:A>AG,NM_198694.3:c.*127dup,\N,1/1,\N,Benign,\N,3_prime_UTR_variant,0.664,0.1505,1KG_AFR_AF,TSPEAR
508228,21:45999512:A>AGG,NM_198694.3:c.*126_*127dup,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,0.61,\N,\N,TSPEAR
508229,21:45999514:G>C,NM_198694.3:c.*126C>G,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,1.659,\N,\N,TSPEAR
508230,21:45999514:G>T,NM_198694.3:c.*126C>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,2.519,\N,\N,TSPEAR
508231,21:45999515:G>A,NM_198694.3:c.*125C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,2.292,0.0023,1KG_AFR_AF,TSPEAR
508232,21:45999515:G>C,NM_198694.3:c.*125C>G,\N,1/1,\N,Benign,\N,3_prime_UTR_variant,0.508,0.0287,1KG_AFR_AF,TSPEAR
508233,21:45999515:G>T,NM_198694.3:c.*125C>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,1.123,\N,\N,TSPEAR
508234,21:45999518:G>A,NM_198694.3:c.*122C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,0.809,0.002,1KG_EAS_AF,TSPEAR
508235,21:45999553:G>A,NM_198694.3:c.*87C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,1.342,\N,\N,TSPEAR
508236,21:45999553:G>C,NM_198694.3:c.*87C>G,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,0.252,0.002,1KG_EAS_AF,TSPEAR
508237,21:45999593:G>A,NM_198694.2:c.*47C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,5.612,0.000114077,EXAC_AFR_AF,TSPEAR
508238,21:45999596:G>C,NM_198694.2:c.*44C>G,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,3.346,0.0000159852,EXAC_NFE_AF,TSPEAR
508239,21:45999604:A>C,NM_198694.2:c.*36T>G,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,1.19,0.0000876117,EXAC_AMR_AF,TSPEAR
508240,21:45999613:A>G,NM_198694.2:c.*27T>C,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,7.258,0.000262973,EXAC_AMR_AF,TSPEAR
508241,21:45999617:G>A,NM_198694.2:c.*23C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,2.989,0.0000317824,EXAC_NFE_AF,TSPEAR
508242,21:45999621:C>T,NM_198694.2:c.*19G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,5.744,0.0000838785,EXAC_SAS_AF,TSPEAR
508243,21:45999623:T>C,NM_198694.2:c.*17A>G,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,3.838,0.0002331,EVS_AA_AF,TSPEAR
508244,21:45999626:C>A,NM_198694.2:c.*14G>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,6.063,\N,\N,TSPEAR
508245,21:45999629:G>A,NM_198694.2:c.*11C>T,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,4.33,0.0000315746,EXAC_NFE_AF,TSPEAR
508246,21:45999633:A>C,NM_198694.2:c.*7T>G,\N,1/1,\N,Benign,\N,3_prime_UTR_variant,0.831,0.1142,1KG_AFR_AF,TSPEAR
508247,21:45999639:C>T,NM_198694.2:c.*1G>A,\N,1/1,\N,Unknown significance,\N,3_prime_UTR_variant,6.183,0.001,1KG_EUR_AF,TSPEAR
508248,21:45999640:T>G,NM_198694.2:c.816A>C,NP_941967.2:p.Ter272CysextTer11,1/1,\N,Unknown significance,\N,stop_lost,0.111,0.000087382,EXAC_AMR_AF,TSPEAR
508249,21:45999641:C>T,NM_198694.2:c.815G>A,NP_941967.2:p.Ter272=,1/1,\N,Unknown significance,\N,stop_retained_variant,7.948,0.000087321,EXAC_AMR_AF,TSPEAR
508250,21:45999646:G>A,NM_198694.2:c.810C>T,NP_941967.2:p.Ala270=,1/1,\N,Unknown significance,\N,synonymous_variant,2.41,0.0008,1KG_AFR_AF,TSPEAR
508251,21:45999650:A>G,NM_198694.2:c.806T>C,NP_941967.2:p.Leu269Pro,1/1,\N,Benign,\N,missense_variant,0.002,0.0051,1KG_SAS_AF,TSPEAR
508252,21:45999652:G>A,NM_198694.2:c.804C>T,NP_941967.2:p.Arg268=,1/1,\N,Unknown significance,\N,synonymous_variant,1.376,0.0023,1KG_AFR_AF,TSPEAR
508253,21:45999653:C>G,NM_198694.2:c.803G>C,NP_941967.2:p.Arg268Pro,1/1,\N,Benign,\N,missense_variant,23.6,0.215988,EXAC_EAS_AF,TSPEAR
508254,21:45999653:C>T,NM_198694.2:c.803G>A,NP_941967.2:p.Arg268His,1/1,\N,Unknown significance,\N,missense_variant,23.7,0.0000466114,EXAC_NFE_AF,TSPEAR
508255,21:45999654:G>A,NM_198694.2:c.802C>T,NP_941967.2:p.Arg268Cys,1/1,\N,Likely benign,\N,missense_variant,23.9,0.003,1KG_AFR_AF,TSPEAR
508256,21:45999654:G>T,NM_198694.2:c.802C>A,NP_941967.2:p.Arg268Ser,1/1,\N,Likely benign,\N,missense_variant,21.8,0.0043,1KG_AMR_AF,TSPEAR
508257,21:45999657:A>G,NM_198694.2:c.799T>C,NP_941967.2:p.Ser267Pro,1/1,\N,Likely benign,\N,missense_variant,14.23,0.0000154804,EXAC_NFE_AF,TSPEAR
508258,21:45999660:A>T,NM_198694.3:c.796T>A,NP_941967.3:p.Cys266Ser,1/1,\N,Unknown significance,\N,missense_variant,22.3,0.001,1KG_SAS_AF,TSPEAR
508259,21:45999661:C>T,NM_198694.2:c.795G>A,NP_941967.2:p.Ala265=,1/1,\N,Benign,\N,synonymous_variant,11.09,0.1089,1KG_AFR_AF,TSPEAR
508260,21:45999662:G>A,NM_198694.2:c.794C>T,NP_941967.2:p.Ala265Val,1/1,\N,Likely benign,\N,missense_variant,0.002,0.000015454,EXAC_NFE_AF,TSPEAR
508261,21:45999663:C>T,NM_198694.2:c.793G>A,NP_941967.2:p.Ala265Thr,1/1,\N,Likely benign,\N,missense_variant,6.439,0.002,1KG_SAS_AF,TSPEAR
508262,21:45999664:G>A,NM_198694.2:c.792C>T,NP_941967.2:p.Pro264=,1/1,\N,Unknown significance,\N,synonymous_variant,3.088,0.000108861,EXAC_AFR_AF,TSPEAR
508263,21:45999665:G>T,NM_198694.2:c.791C>A,NP_941967.2:p.Pro264His,1/1,\N,Unknown significance,\N,missense_variant,23.1,0.0000624922,EXAC_SAS_AF,TSPEAR
508264,21:45999666:G>A,NM_198694.2:c.790C>T,NP_941967.2:p.Pro264Ser,1/1,\N,Unknown significance,\N,missense_variant,23,0.0000623286,EXAC_SAS_AF,TSPEAR
508265,21:45999668:C>T,NM_198694.2:c.788G>A,NP_941967.2:p.Arg263His,1/1,\N,Likely benign,\N,missense_variant,12.72,0.000697837,EXAC_AMR_AF,TSPEAR
508266,21:45999669:G>A,NM_198694.2:c.787C>T,NP_941967.2:p.Arg263Cys,1/1,\N,Unknown significance,\N,missense_variant,24.5,0.00380518,EXAC_FIN_AF,TSPEAR
508267,21:45999671:C>G,NM_198694.2:c.785G>C,NP_941967.2:p.Cys262Ser,1/1,\N,Unknown significance,\N,missense_variant,23.5,0.000117069,EVS_EA_AF,TSPEAR
508268,21:45999674:A>AG,NM_198694.2:c.781dup,NP_941967.2:p.Leu261ProfsTer34,1/1,\N,Unknown significance,\N,frameshift_variant,26.1,0.000152068,EXAC_FIN_AF,TSPEAR
508269,21:45999676:G>A,NM_198694.2:c.780C>T,NP_941967.2:p.Leu260=,1/1,\N,Unknown significance,\N,synonymous_variant,1.03,0.000912825,EVS_AA_AF,TSPEAR
508270,21:45999682:C>T,NM_198694.2:c.774G>A,NP_941967.2:p.Val258=,1/1,\N,Benign,\N,synonymous_variant,8.889,0.1142,1KG_AFR_AF,TSPEAR
508271,21:45999684:C>T,NM_198694.3:c.772G>A,NP_941967.3:p.Val258Met,1/1,\N,Likely benign,\N,missense_variant,21.7,0.0014,1KG_AMR_AF,TSPEAR
508272,21:45999685:G>A,NM_198694.2:c.771C>T,NP_941967.2:p.Cys257=,1/1,\N,Unknown significance,\N,synonymous_variant,0.548,0.001,1KG_EAS_AF,TSPEAR
508273,21:45999687:A>C,NM_198694.2:c.769T>G,NP_941967.2:p.Cys257Gly,1/1,\N,Unknown significance,\N,missense_variant,13.36,0.0000609533,EXAC_SAS_AF,TSPEAR
508274,21:45999688:G>A,NM_198694.2:c.768C>T,NP_941967.2:p.Ser256=,1/1,\N,Unknown significance,\N,synonymous_variant,1.117,0.000455789,EXAC_FIN_AF,TSPEAR
508275,21:45999691:G>A,NM_198694.2:c.765C>T,NP_941967.2:p.Ala255=,1/1,\N,Unknown significance,\N,synonymous_variant,1.37,\N,\N,TSPEAR
508276,21:45999694:C>T,NM_198694.2:c.762G>A,NP_941967.2:p.Pro254=,1/1,\N,Unknown significance,\N,synonymous_variant,10.63,0.0008,1KG_AFR_AF,TSPEAR
508277,21:45999695:G>T,NM_198694.2:c.761C>A,NP_941967.2:p.Pro254Gln,1/1,\N,Likely benign,\N,missense_variant,16.15,0.000243576,EXAC_SAS_AF,TSPEAR
508278,21:45999696:G>A,NM_198694.2:c.760C>T,NP_941967.2:p.Pro254Ser,1/1,\N,Unknown significance,\N,missense_variant,17.79,0.0000152393,EXAC_NFE_AF,TSPEAR
508279,21:45999698:C>T,NM_198694.2:c.758G>A,NP_941967.2:p.Arg253His,1/1,\N,Unknown significance,\N,missense_variant,16.29,0.000243516,EXAC_SAS_AF,TSPEAR
508280,21:45999699:G>A,NM_198694.2:c.757C>T,NP_941967.2:p.Arg253Cys,1/1,\N,Unknown significance,\N,missense_variant,16.29,0.000303582,EXAC_FIN_AF,TSPEAR
508281,21:45999702:A>C,NM_198694.2:c.754T>G,NP_941967.2:p.Cys252Gly,1/1,\N,Unknown significance,\N,missense_variant,7.617,0.0000152036,EXAC_NFE_AF,TSPEAR
508282,21:45999703:G>A,NM_198694.2:c.753C>T,NP_941967.2:p.Cys251=,1/1,\N,Unknown significance,\N,synonymous_variant,0.037,0.000261142,EXAC_AMR_AF,TSPEAR
508283,21:45999704:C>T,NM_198694.3:c.752G>A,NP_941967.3:p.Cys251Tyr,1/1,\N,Unknown significance,\N,missense_variant,19.29,0.000261142,EXAC_AMR_AF,TSPEAR
508284,21:45999709:G>A,NM_198694.2:c.747C>T,NP_941967.2:p.Ala249=,1/1,\N,Unknown significance,\N,synonymous_variant,0.26,0.00111857,EXAC_OTH_AF,TSPEAR
508285,21:45999710:G>A,NM_198694.2:c.746C>T,NP_941967.2:p.Ala249Val,1/1,\N,Likely benign,\N,missense_variant,23.4,0.000303398,EXAC_FIN_AF,TSPEAR
508286,21:45999711:C>A,NM_198694.2:c.745G>T,NP_941967.2:p.Ala249Ser,1/1,\N,Likely benign,\N,missense_variant,0.008,0.00176222,EXAC_EAS_AF,TSPEAR
508287,21:45999711:C>G,NM_198694.2:c.745G>C,NP_941967.2:p.Ala249Pro,1/1,\N,Likely benign,\N,missense_variant,0.001,0.000117481,EXAC_EAS_AF,TSPEAR
508288,21:45999713:T>TGGTAGGAGGAGGCAGGGGCAC,NM_198694.2:c.722_742dup,NP_941967.2:p.Tyr247_Gln248insArgAlaProAlaSerSerTyr,1/1,\N,Unknown significance,\N,inframe_insertion,0.405,\N,\N,TSPEAR
508289,21:45999715:G>A,NM_198694.2:c.741C>T,NP_941967.2:p.Tyr247=,1/1,\N,Unknown significance,\N,synonymous_variant,0.01,0.0000302682,EXAC_NFE_AF,TSPEAR
508290,21:45999716:T>C,NM_198694.2:c.740A>G,NP_941967.2:p.Tyr247Cys,1/1,\N,Benign,\N,missense_variant,0.002,0.2133,1KG_AFR_AF,TSPEAR
508291,21:45999719:G>A,NM_198694.2:c.737C>T,NP_941967.2:p.Ser246Phe,1/1,\N,Likely benign,\N,missense_variant,19.55,0.001,1KG_SAS_AF,TSPEAR
508292,21:45999719:G>T,NM_198694.2:c.737C>A,NP_941967.2:p.Ser246Tyr,1/1,\N,Likely benign,\N,missense_variant,17.22,0.0000151039,EXAC_NFE_AF,TSPEAR
508293,21:45999720:A>T,NM_198694.2:c.736T>A,NP_941967.2:p.Ser246Thr,1/1,\N,Unknown significance,\N,missense_variant,13.85,\N,\N,TSPEAR
508294,21:45999723:A>C,NM_198694.2:c.733T>G,NP_941967.2:p.Ser245Ala,1/1,\N,Benign,\N,missense_variant,11.06,0.0303,1KG_AFR_AF,TSPEAR
508295,21:45999723:AGG>A,NM_198694.2:c.731_732del,NP_941967.2:p.Ala244ValfsTer50,1/1,\N,Unknown significance,\N,frameshift_variant,23.7,\N,\N,TSPEAR
508296,21:45999724:G>C,NM_198694.2:c.732C>G,NP_941967.2:p.Ala244=,1/1,\N,Benign,\N,synonymous_variant,0.024,0.115,1KG_AFR_AF,TSPEAR
508297,21:45999724:GG>CA,NM_198694.3:c.731_732delinsTG,NP_941967.3:p.Ala244Val,1/1,\N,Unknown significance,\N,missense_variant,\N,\N,\N,TSPEAR
508298,21:45999724:GGCA>CACG,NM_198694.2:c.729_732delinsCGTG,NP_941967.2:p.Ala244Val,1/1,\N,Unknown significance,\N,missense_variant,3.966,\N,\N,TSPEAR
508299,21:45999725:G>A,NM_198694.2:c.731C>T,NP_941967.2:p.Ala244Val,1/1,\N,Benign,\N,missense_variant,19.57,0.115,1KG_AFR_AF,TSPEAR
508300,21:45999726:C>T,NM_198694.2:c.730G>A,NP_941967.2:p.Ala244Thr,1/1,\N,Unknown significance,\N,missense_variant,10.75,0.0014,1KG_AMR_AF,TSPEAR
508301,21:45999727:A>ACG,NM_198694.2:c.728_729insCG,NP_941967.2:p.Ala244ValfsTer?,1/1,\N,Unknown significance,\N,frameshift_variant,23.2,\N,\N,TSPEAR
508302,21:45999727:A>G,NM_198694.2:c.729T>C,NP_941967.2:p.Pro243=,1/1,\N,Benign,\N,synonymous_variant,0.004,0.115,1KG_AFR_AF,TSPEAR
508303,21:45999731:G>T,NM_198694.2:c.725C>A,NP_941967.2:p.Ala242Asp,1/1,\N,Unknown significance,\N,missense_variant,22.8,0.000454545,EXAC_FIN_AF,TSPEAR
508304,21:45999732:C>A,NM_198694.2:c.724G>T,NP_941967.2:p.Ala242Ser,1/1,\N,Likely benign,\N,missense_variant,15.96,0.0000867754,EXAC_AMR_AF,TSPEAR
508305,21:45999747:T>C,NM_198694.2:c.709A>G,NP_941967.2:p.Ile237Val,1/1,\N,Likely benign,\N,missense_variant,0.001,0.00116306,EXAC_EAS_AF,TSPEAR
508306,21:45999748:G>A,NM_198694.2:c.708C>T,NP_941967.2:p.Pro236=,1/1,\N,Unknown significance,\N,synonymous_variant,0.1,0.001,1KG_EUR_AF,TSPEAR
508307,21:45999750:G>T,NM_198694.2:c.706C>A,NP_941967.2:p.Pro236Thr,1/1,\N,Unknown significance,\N,missense_variant,12.31,0.000121286,EXAC_SAS_AF,TSPEAR
508308,21:45999751:C>T,NM_198694.2:c.705G>A,NP_941967.2:p.Val235=,1/1,\N,Unknown significance,\N,synonymous_variant,2.805,0.0000606428,EXAC_SAS_AF,TSPEAR
508309,21:45999753:C>G,NM_198694.2:c.703G>C,NP_941967.2:p.Val235Leu,1/1,\N,Benign,\N,missense_variant,23.1,0.227686,EXAC_EAS_AF,TSPEAR
508310,21:45999753:C>T,NM_198694.2:c.703G>A,NP_941967.2:p.Val235Met,1/1,\N,Unknown significance,\N,missense_variant,23.2,0.00019988,EXAC_AFR_AF,TSPEAR
508311,21:45999753:C>CGCAGCAGGCGGGCCTGCATATGGGGCGGCAGAGGAGGGACACGCAGGAGGCCGGGCGGCAGCAGCTGGCCTGGCAGGAGGAGGCAGGGGCACAGCAGGAGGAGATGGGCAG,NM_198694.2:c.702_703insCTGCCCATCTCCTCCTGCTGTGCCCCTGCCTCCTCCTGCCAGGCCAGCTGCTGCCGCCCGGCCTCCTGCGTGTCCCTCCTCTGCCGCCCCATATGCAGGCCCGCCTGCTGC,NP_941967.2:p.Cys234_Val235insLeuProIleSerSerCysCysAlaProAlaSerSerCysGlnAlaSerCysCysArgProAlaSerCysValSerLeuLeuCysArgProIleCysArgProAlaCysCys,1/1,\N,Unknown significance,\N,inframe_insertion,0.015,0.000015024,EXAC_NFE_AF,TSPEAR
508312,21:45999754:G>A,NM_198694.2:c.702C>T,NP_941967.2:p.Cys234=,1/1,\N,Unknown significance,\N,synonymous_variant,2.375,0.00104384,EXAC_EAS_AF,TSPEAR
508313,21:45999755:C>T,NM_198694.2:c.701G>A,NP_941967.2:p.Cys234Tyr,1/1,\N,Unknown significance,\N,missense_variant,23,0.0000150191,EXAC_NFE_AF,TSPEAR
508314,21:45999762:C>T,NM_198694.2:c.694G>A,NP_941967.2:p.Ala232Thr,1/1,\N,Likely benign,\N,missense_variant,13.23,0.0000864902,EXAC_AMR_AF,TSPEAR
508315,21:45999763:G>A,NM_198694.2:c.693C>T,NP_941967.2:p.Pro231=,1/1,\N,Benign,\N,synonymous_variant,4.22,0.115,1KG_AFR_AF,TSPEAR
508316,21:45999767:C>T,NM_198694.2:c.689G>A,NP_941967.2:p.Arg230Lys,1/1,\N,Unknown significance,\N,missense_variant,21.3,\N,\N,TSPEAR
508317,21:45999768:T>G,NM_198694.2:c.688A>C,NP_941967.2:p.Arg230=,1/1,\N,Unknown significance,\N,synonymous_variant,0.437,\N,\N,TSPEAR
508318,21:45999769:G>C,NM_198694.2:c.687C>G,NP_941967.2:p.Cys229Trp,1/1,\N,Unknown significance,\N,missense_variant,24.2,0.000226963,EVS_AA_AF,TSPEAR
508319,21:45999772:T>C,NM_198694.2:c.684A>G,NP_941967.2:p.Ile228Met,1/1,\N,Likely benign,\N,missense_variant,11.96,0.000115848,EXAC_EAS_AF,TSPEAR
508320,21:45999774:T>C,NM_198694.2:c.682A>G,NP_941967.2:p.Ile228Val,1/1,\N,Likely benign,\N,missense_variant,0.001,0.00331126,EXAC_OTH_AF,TSPEAR
508321,21:45999775:G>A,NM_198694.2:c.681C>T,NP_941967.2:p.Pro227=,1/1,\N,Unknown significance,\N,synonymous_variant,2.417,\N,\N,TSPEAR
508322,21:45999779:C>T,NM_198694.2:c.677G>A,NP_941967.2:p.Arg226His,1/1,\N,Unknown significance,\N,missense_variant,17.87,0.000259202,EXAC_AMR_AF,TSPEAR
508323,21:45999780:G>A,NM_198694.2:c.676C>T,NP_941967.2:p.Arg226Cys,1/1,\N,Unknown significance,\N,missense_variant,24.7,0.0000450018,EXAC_NFE_AF,TSPEAR
508324,21:45999791:G>A,NM_198694.2:c.665C>T,NP_941967.2:p.Ser222Phe,1/1,\N,Unknown significance,\N,missense_variant,24.7,0.0000973899,EXAC_AFR_AF,TSPEAR
508325,21:45999795:C>T,NM_198694.2:c.661G>A,NP_941967.2:p.Val221Met,1/1,\N,Unknown significance,\N,missense_variant,22.1,0.000231481,EXAC_EAS_AF,TSPEAR
508326,21:45999796:G>A,NM_198694.2:c.660C>T,NP_941967.2:p.Ser220=,1/1,\N,Unknown significance,\N,synonymous_variant,8.921,0.00090799,EXAC_FIN_AF,TSPEAR
508327,21:45999799:G>A,NM_198694.2:c.657C>T,NP_941967.2:p.Ser219=,1/1,\N,Unknown significance,\N,synonymous_variant,2.502,0.0000299769,EXAC_NFE_AF,TSPEAR
508328,21:45999800:G>A,NM_198694.2:c.656C>T,NP_941967.2:p.Ser219Phe,1/1,\N,Unknown significance,\N,missense_variant,24.3,0.0023,1KG_AFR_AF,TSPEAR
508329,21:45999813:A>C,NM_198694.2:c.643T>G,NP_941967.2:p.Cys215Gly,1/1,\N,Unknown significance,\N,missense_variant,23.7,0.0000963391,EXAC_AFR_AF,TSPEAR
508330,21:45999816:A>T,NM_198694.2:c.640T>A,NP_941967.2:p.Cys214Ser,1/1,\N,Unknown significance,\N,missense_variant,23.2,0.000060562,EXAC_SAS_AF,TSPEAR
508331,21:45999817:G>A,NM_198694.2:c.639C>T,NP_941967.2:p.Ser213=,1/1,\N,Unknown significance,\N,synonymous_variant,4.956,0.0000149849,EXAC_NFE_AF,TSPEAR
508332,21:45999818:G>A,NM_198694.2:c.638C>T,NP_941967.2:p.Ser213Phe,1/1,\N,Likely benign,\N,missense_variant,23.3,0.000232558,EVS_EA_AF,TSPEAR
508333,21:45999819:A>C,NM_198694.2:c.637T>G,NP_941967.2:p.Ser213Ala,1/1,\N,Likely benign,\N,missense_variant,13.56,0.0000149844,EXAC_NFE_AF,TSPEAR
508334,21:45999823:G>T,NM_198694.2:c.633C>A,NP_941967.2:p.Thr211=,1/1,\N,Unknown significance,\N,synonymous_variant,2.794,\N,\N,TSPEAR
508335,21:45999835:C>G,NM_198694.2:c.621G>C,NP_941967.2:p.Pro207=,1/1,\N,Unknown significance,\N,synonymous_variant,9.66,0.0000149835,EXAC_NFE_AF,TSPEAR
508336,21:45999835:C>T,NM_198694.2:c.621G>A,NP_941967.2:p.Pro207=,1/1,\N,Benign,\N,synonymous_variant,12.87,0.0091,1KG_AFR_AF,TSPEAR
508337,21:45999836:G>A,NM_198694.2:c.620C>T,NP_941967.2:p.Pro207Leu,1/1,\N,Benign,\N,missense_variant,23.4,0.1248,1KG_AFR_AF,TSPEAR
508338,21:45999840:G>A,NM_198694.2:c.616C>T,NP_941967.2:p.Gln206Ter,1/1,\N,Unknown significance,\N,stop_gained,35,0.000060562,EXAC_SAS_AF,TSPEAR
508339,21:45999841:A>G,NM_198694.2:c.615T>C,NP_941967.2:p.Cys205=,1/1,\N,Benign,\N,synonymous_variant,0.198,0.0061,1KG_AFR_AF,TSPEAR
508340,21:45999846:T>A,NM_198694.2:c.610A>T,NP_941967.2:p.Ser204Cys,1/1,\N,Likely benign,\N,missense_variant,12.83,0.000116279,EVS_EA_AF,TSPEAR
508341,21:45999846:T>C,NM_198694.2:c.610A>G,NP_941967.2:p.Ser204Gly,1/1,\N,Likely benign,\N,missense_variant,4.849,0.001,1KG_SAS_AF,TSPEAR
508342,21:45999847:AGACTGCTGGCAGCATGAAGTG>A,NM_198694.2:c.588_608del,NP_941967.2:p.Thr197_Ser203del,1/1,\N,Unknown significance,\N,inframe_deletion,12.92,\N,\N,TSPEAR
508343,21:45999849:A>G,NM_198694.2:c.607T>C,NP_941967.2:p.Ser203Pro,1/1,\N,Unknown significance,\N,missense_variant,18.94,\N,\N,TSPEAR
508344,21:45999850:C>T,NM_198694.2:c.606G>A,NP_941967.2:p.Gln202=,1/1,\N,Unknown significance,\N,synonymous_variant,8.791,0.00257031,EXAC_FIN_AF,TSPEAR
508345,21:45999856:G>T,NM_198694.2:c.600C>A,NP_941967.2:p.Cys200Ter,1/1,\N,Unknown significance,\N,stop_gained,35,0.000060562,EXAC_SAS_AF,TSPEAR
508346,21:45999866:G>T,NM_198694.2:c.590C>A,NP_941967.2:p.Thr197Asn,1/1,\N,Unknown significance,\N,missense_variant,21.7,0.000121124,EXAC_SAS_AF,TSPEAR
508347,21:45999867:T>A,NM_198694.2:c.589A>T,NP_941967.2:p.Thr197Ser,1/1,\N,Likely benign,\N,missense_variant,0.001,0.000121124,EXAC_SAS_AF,TSPEAR
508348,21:45999869:G>A,NM_198694.2:c.587C>T,NP_941967.2:p.Ser196Phe,1/1,\N,Unknown significance,\N,missense_variant,23.2,0.00110132,EXAC_OTH_AF,TSPEAR
508349,21:45999876:C>T,NM_198694.2:c.580G>A,NP_941967.2:p.Gly194Arg,1/1,\N,Likely benign,\N,missense_variant,19.55,\N,\N,TSPEAR
508350,21:45999878:G>A,NM_198694.2:c.578C>T,NP_941967.2:p.Ser193Phe,1/1,\N,Likely benign,\N,missense_variant,23.2,0.000060562,EXAC_SAS_AF,TSPEAR
508351,21:45999878:G>C,NM_198694.2:c.578C>G,NP_941967.2:p.Ser193Cys,1/1,\N,Benign,\N,missense_variant,13.85,0.0053,1KG_AFR_AF,TSPEAR
508352,21:45999885:C>T,NM_198694.2:c.571G>A,NP_941967.2:p.Val191Ile,1/1,\N,Benign,\N,missense_variant,10.56,0.1271,1KG_AFR_AF,TSPEAR
508353,21:45999886:G>A,NM_198694.2:c.570C>T,NP_941967.2:p.Pro190=,1/1,\N,Unknown significance,\N,synonymous_variant,6.761,\N,\N,TSPEAR
508354,21:45999890:A>G,NM_198694.2:c.566T>C,NP_941967.2:p.Val189Ala,1/1,\N,Likely benign,\N,missense_variant,5.224,0.000346661,EXAC_EAS_AF,TSPEAR
508355,21:45999893:C>T,NM_198694.2:c.563G>A,NP_941967.2:p.Cys188Tyr,1/1,\N,Unknown significance,\N,missense_variant,22.7,0.00110132,EXAC_OTH_AF,TSPEAR
508356,21:45999903:G>A,NM_198694.3:c.553C>T,NP_941967.3:p.Pro185Ser,1/1,\N,Likely benign,\N,missense_variant,11.35,0.000029967,EXAC_NFE_AF,TSPEAR
508357,21:45999904:T>C,NM_198694.2:c.552A>G,NP_941967.2:p.Lys184=,1/1,\N,Unknown significance,\N,synonymous_variant,0.003,\N,\N,TSPEAR
508358,21:45999908:A>C,NM_198694.2:c.548T>G,NP_941967.2:p.Phe183Cys,1/1,\N,Benign,\N,missense_variant,0.002,0.2489,1KG_AFR_AF,TSPEAR
508359,21:45999917:G>A,NM_198694.2:c.539C>T,NP_941967.2:p.Pro180Leu,1/1,\N,Likely benign,\N,missense_variant,19.55,0.0000149835,EXAC_NFE_AF,TSPEAR
508360,21:45999918:G>C,NM_198694.2:c.538C>G,NP_941967.2:p.Pro180Ala,1/1,\N,Unknown significance,\N,missense_variant,15.81,0.0043,1KG_AMR_AF,TSPEAR
508361,21:45999927:A>G,NM_198694.2:c.529T>C,NP_941967.2:p.Cys177Arg,1/1,\N,Likely benign,\N,missense_variant,0.003,0.0000963391,EXAC_AFR_AF,TSPEAR
508362,21:45999931:A>G,NM_198694.2:c.525T>C,NP_941967.2:p.Pro175=,1/1,\N,Unknown significance,\N,synonymous_variant,0.003,0.000060562,EXAC_SAS_AF,TSPEAR
508363,21:45999936:C>A,NM_198694.2:c.520G>T,NP_941967.2:p.Val174Leu,1/1,\N,Unknown significance,\N,missense_variant,18.92,0.0000149835,EXAC_NFE_AF,TSPEAR
508364,21:45999936:C>T,NM_198694.2:c.520G>A,NP_941967.2:p.Val174Met,1/1,\N,Unknown significance,\N,missense_variant,22.7,0.00110132,EXAC_OTH_AF,TSPEAR
508365,21:45999938:T>C,NM_198694.2:c.518A>G,NP_941967.2:p.Tyr173Cys,1/1,\N,Likely benign,\N,missense_variant,0.001,0.0000899011,EXAC_NFE_AF,TSPEAR
508366,21:45999945:A>C,NM_198694.2:c.511T>G,NP_941967.2:p.Ser171Ala,1/1,\N,Likely benign,\N,missense_variant,0.001,0.000231107,EXAC_EAS_AF,TSPEAR
508367,21:45999953:C>T,NM_198694.2:c.503G>A,NP_941967.2:p.Cys168Tyr,1/1,\N,Unknown significance,\N,missense_variant,14.77,\N,\N,TSPEAR
508368,21:45999956:G>A,NM_198694.2:c.500C>T,NP_941967.2:p.Pro167Leu,1/1,\N,Unknown significance,\N,missense_variant,7.899,0.001,1KG_EAS_AF,TSPEAR
508369,21:45999957:G>A,NM_198694.2:c.499C>T,NP_941967.2:p.Pro167Ser,1/1,\N,Likely benign,\N,missense_variant,0.026,\N,\N,TSPEAR
508370,21:45999961:G>A,NM_198694.2:c.495C>T,NP_941967.2:p.Ser165=,1/1,\N,Unknown significance,\N,synonymous_variant,0.424,0.000115554,EXAC_EAS_AF,TSPEAR
508371,21:45999967:G>A,NM_198694.2:c.489C>T,NP_941967.2:p.Cys163=,1/1,\N,Unknown significance,\N,synonymous_variant,2.015,0.000029967,EXAC_NFE_AF,TSPEAR
508372,21:45999974:G>A,NM_198694.2:c.482C>T,NP_941967.2:p.Thr161Ile,1/1,\N,Likely benign,\N,missense_variant,14.12,0.0000963948,EXAC_AFR_AF,TSPEAR
508373,21:45999975:T>C,NM_198694.2:c.481A>G,NP_941967.2:p.Thr161Ala,1/1,\N,Benign,\N,missense_variant,0.001,0.005,1KG_EUR_AF,TSPEAR
508374,21:45999976:C>T,NM_198694.2:c.480G>A,NP_941967.2:p.Pro160=,1/1,\N,Benign,\N,synonymous_variant,12.43,0.005,1KG_EUR_AF,TSPEAR
508375,21:45999977:G>A,NM_198694.3:c.479C>T,NP_941967.3:p.Pro160Leu,1/1,\N,Unknown significance,\N,missense_variant,21.4,0.000060562,EXAC_SAS_AF,TSPEAR
508376,21:45999978:G>A,NM_198694.2:c.478C>T,NP_941967.2:p.Pro160Ser,1/1,\N,Likely benign,\N,missense_variant,10.41,0.000060562,EXAC_SAS_AF,TSPEAR
508377,21:45999979:C>A,NM_198694.2:c.477G>T,NP_941967.2:p.Gln159His,1/1,\N,Unknown significance,\N,missense_variant,18.75,\N,\N,TSPEAR
508378,21:45999982:G>A,NM_198694.2:c.474C>T,NP_941967.2:p.Cys158=,1/1,\N,Unknown significance,\N,synonymous_variant,5.784,0.000060562,EXAC_SAS_AF,TSPEAR
508379,21:45999991:A>C,NM_198694.2:c.465T>G,NP_941967.2:p.His155Gln,1/1,\N,Likely benign,\N,missense_variant,0.012,0.000121124,EXAC_SAS_AF,TSPEAR
508380,21:45999992:T>C,NM_198694.2:c.464A>G,NP_941967.2:p.His155Arg,1/1,\N,Unknown significance,\N,missense_variant,7.56,0.0000149835,EXAC_NFE_AF,TSPEAR
508381,21:45999992:T>G,NM_198694.2:c.464A>C,NP_941967.2:p.His155Pro,1/1,\N,Unknown significance,\N,missense_variant,8.833,0.000116279,EVS_EA_AF,TSPEAR
508382,21:45999993:G>T,NM_198694.2:c.463C>A,NP_941967.2:p.His155Asn,1/1,\N,Unknown significance,\N,missense_variant,9.973,0.000181686,EXAC_SAS_AF,TSPEAR
508383,21:46000002:A>G,NM_198694.2:c.454T>C,NP_941967.2:p.Cys152Arg,1/1,\N,Unknown significance,\N,missense_variant,21.4,0.000060562,EXAC_SAS_AF,TSPEAR
508384,21:46000007:G>T,NM_198694.2:c.449C>A,NP_941967.2:p.Ser150Tyr,1/1,\N,Likely benign,\N,missense_variant,7.035,\N,\N,TSPEAR
508385,21:46000019:G>T,NM_198694.2:c.437C>A,NP_941967.2:p.Ser146Tyr,1/1,\N,Likely benign,\N,missense_variant,10.14,\N,\N,TSPEAR
508386,21:46000022:C>G,NM_198694.2:c.434G>C,NP_941967.2:p.Cys145Ser,1/1,\N,Likely benign,\N,missense_variant,3.79,0.00029967,EXAC_NFE_AF,TSPEAR
508387,21:46000030:C>T,NM_198694.2:c.426G>A,NP_941967.2:p.Val142=,1/1,\N,Unknown significance,\N,synonymous_variant,9.435,0.0000863707,EXAC_AMR_AF,TSPEAR
508388,21:46000033:A>G,NM_198694.2:c.423T>C,NP_941967.2:p.Cys141=,1/1,\N,Unknown significance,\N,synonymous_variant,0.019,0.0000965437,EXAC_AFR_AF,TSPEAR
508389,21:46000034:C>G,NM_198694.2:c.422G>C,NP_941967.2:p.Cys141Ser,1/1,\N,Likely benign,\N,missense_variant,12.81,\N,\N,TSPEAR
508390,21:46000037:C>CCG,NM_198694.2:c.418_419insCG,NP_941967.2:p.Cys140SerfsTer?,1/1,\N,Unknown significance,\N,frameshift_variant,23.9,\N,\N,TSPEAR
508391,21:46000040:ACG>A,NM_198694.2:c.414_415del,NP_941967.2:p.Cys140LeufsTer7,1/1,\N,Unknown significance,\N,frameshift_variant,24.6,\N,\N,TSPEAR
508392,21:46000041:C>T,NM_198694.2:c.415G>A,NP_941967.2:p.Val139Met,1/1,\N,Likely benign,\N,missense_variant,17.4,0.000115554,EXAC_EAS_AF,TSPEAR
508393,21:46000042:G>A,NM_198694.2:c.414C>T,NP_941967.2:p.Pro138=,1/1,\N,Unknown significance,\N,synonymous_variant,11.26,0.000226963,EVS_AA_AF,TSPEAR
508394,21:46000054:G>A,NM_198694.2:c.402C>T,NP_941967.2:p.Val134=,1/1,\N,Unknown significance,\N,synonymous_variant,4.897,\N,\N,TSPEAR
508395,21:46000057:A>G,NM_198694.2:c.399T>C,NP_941967.2:p.Pro133=,1/1,\N,Unknown significance,\N,synonymous_variant,0.036,0.000060562,EXAC_SAS_AF,TSPEAR
508396,21:46000058:G>A,NM_198694.2:c.398C>T,NP_941967.2:p.Pro133Leu,1/1,\N,Unknown significance,\N,missense_variant,20.4,0.000060562,EXAC_SAS_AF,TSPEAR
508397,21:46000059:G>A,NM_198694.2:c.397C>T,NP_941967.2:p.Pro133Ser,1/1,\N,Likely benign,\N,missense_variant,6.539,0.0000149835,EXAC_NFE_AF,TSPEAR
508398,21:46000071:A>C,NM_198694.2:c.385T>G,NP_941967.2:p.Ser129Ala,1/1,\N,Likely benign,\N,missense_variant,0.001,\N,\N,TSPEAR
508399,21:46000072:C>G,NM_198694.2:c.384G>C,NP_941967.2:p.Gln128His,1/1,\N,Likely benign,\N,missense_variant,10.66,\N,\N,TSPEAR
508400,21:46000075:C>T,NM_198694.2:c.381G>A,NP_941967.2:p.Gln127=,1/1,\N,Unknown significance,\N,synonymous_variant,4.567,0.0000149835,EXAC_NFE_AF,TSPEAR
508401,21:46000080:A>T,NM_198694.2:c.376T>A,NP_941967.2:p.Cys126Ser,1/1,\N,Unknown significance,\N,missense_variant,5.281,0.0014,1KG_AMR_AF,TSPEAR
508402,21:46000082:G>C,NM_198694.2:c.374C>G,NP_941967.2:p.Ser125Cys,1/1,\N,Likely benign,\N,missense_variant,0.01,0.000116279,EVS_EA_AF,TSPEAR
508403,21:46000088:G>A,NM_198694.2:c.368C>T,NP_941967.2:p.Ser123Phe,1/1,\N,Unknown significance,\N,missense_variant,14.9,0.0000149835,EXAC_NFE_AF,TSPEAR
508404,21:46000090:G>C,NM_198694.2:c.366C>G,NP_941967.2:p.Ala122=,1/1,\N,Unknown significance,\N,synonymous_variant,0.29,0.0000863707,EXAC_AMR_AF,TSPEAR
508405,21:46000097:C>G,NM_198694.2:c.359G>C,NP_941967.2:p.Cys120Ser,1/1,\N,Unknown significance,\N,missense_variant,12.71,0.000226963,EVS_AA_AF,TSPEAR
508406,21:46000101:T>C,NM_198694.2:c.355A>G,NP_941967.2:p.Thr119Ala,1/1,\N,Likely benign,\N,missense_variant,0.001,0.000115554,EXAC_EAS_AF,TSPEAR
508407,21:46000104:G>A,NM_198694.2:c.352C>T,NP_941967.2:p.Pro118Ser,1/1,\N,Unknown significance,\N,missense_variant,10.13,0.000060562,EXAC_SAS_AF,TSPEAR
508408,21:46000104:G>C,NM_198694.2:c.352C>G,NP_941967.2:p.Pro118Ala,1/1,\N,Unknown significance,\N,missense_variant,11.97,0.000116279,EVS_EA_AF,TSPEAR
508409,21:46000107:G>A,NM_198694.2:c.349C>T,NP_941967.2:p.Gln117Ter,1/1,\N,Unknown significance,\N,stop_gained,34,0.000115554,EXAC_EAS_AF,TSPEAR
508410,21:46000108:G>C,NM_198694.2:c.348C>G,NP_941967.2:p.Cys116Trp,1/1,\N,Unknown significance,\N,missense_variant,23.5,\N,\N,TSPEAR
508411,21:46000110:AGCTAGACTGCTGGCAGCAT>A,NM_198694.2:c.327_345del,NP_941967.2:p.Cys110AlafsTer?,1/1,\N,Unknown significance,\N,frameshift_variant,29.6,\N,\N,TSPEAR
508412,21:46000119:G>A,NM_198694.2:c.337C>T,NP_941967.2:p.Gln113Ter,1/1,\N,Unknown significance,\N,stop_gained,35,0.000181686,EXAC_SAS_AF,TSPEAR
508413,21:46000121:T>C,NM_198694.2:c.335A>G,NP_941967.2:p.Gln112Arg,1/1,\N,Unknown significance,\N,missense_variant,14.14,0.000060562,EXAC_SAS_AF,TSPEAR
508414,21:46000124:C>T,NM_198694.2:c.332G>A,NP_941967.2:p.Cys111Tyr,1/1,\N,Unknown significance,\N,missense_variant,22.8,0.000781861,EXAC_AFR_AF,TSPEAR
508415,21:46000129:T>G,NM_198694.2:c.327A>C,NP_941967.2:p.Ser109=,1/1,\N,Unknown significance,\N,synonymous_variant,5.809,0.003,1KG_AFR_AF,TSPEAR
508416,21:46000130:G>A,NM_198694.2:c.326C>T,NP_941967.2:p.Ser109Leu,1/1,\N,Likely benign,\N,missense_variant,21.1,0.0023,1KG_AFR_AF,TSPEAR
508417,21:46000145:G>A,NM_198694.2:c.311C>T,NP_941967.2:p.Ser104Phe,1/1,\N,Likely benign,\N,missense_variant,5.731,\N,\N,TSPEAR
508418,21:46000145:G>C,NM_198694.2:c.311C>G,NP_941967.2:p.Ser104Cys,1/1,\N,Likely benign,\N,missense_variant,0.002,\N,\N,TSPEAR
508419,21:46000148:C>T,NM_198694.2:c.308G>A,NP_941967.2:p.Cys103Tyr,1/1,\N,Unknown significance,\N,missense_variant,13.71,\N,\N,TSPEAR
508420,21:46000159:G>A,NM_198694.2:c.297C>T,NP_941967.2:p.Cys99=,1/1,\N,Unknown significance,\N,synonymous_variant,0.711,0.001,1KG_EAS_AF|1KG_SAS_AF,TSPEAR
508421,21:46000163:C>A,NM_198694.2:c.293G>T,NP_941967.2:p.Cys98Phe,1/1,\N,Unknown significance,\N,missense_variant,17.31,0.0008,1KG_AFR_AF,TSPEAR
508422,21:46000165:C>G,NM_198694.2:c.291G>C,NP_941967.2:p.Val97=,1/1,\N,Unknown significance,\N,synonymous_variant,0.555,0.000227169,EVS_AA_AF,TSPEAR
508423,21:46000165:C>T,NM_198694.2:c.291G>A,NP_941967.2:p.Val97=,1/1,\N,Unknown significance,\N,synonymous_variant,4.377,0.0000989707,EXAC_AFR_AF,TSPEAR
508424,21:46000170:G>T,NM_198694.2:c.286C>A,NP_941967.2:p.Pro96Thr,1/1,\N,Unknown significance,\N,missense_variant,2.033,\N,\N,TSPEAR
508425,21:46000175:C>T,NM_198694.2:c.281G>A,NP_941967.2:p.Cys94Tyr,1/1,\N,Unknown significance,\N,missense_variant,17,\N,\N,TSPEAR
508426,21:46000176:A>T,NM_198694.2:c.280T>A,NP_941967.2:p.Cys94Ser,1/1,\N,Unknown significance,\N,missense_variant,12.27,0.00022748,EVS_AA_AF,TSPEAR
508427,21:46000178:C>A,NM_198694.2:c.278G>T,NP_941967.2:p.Cys93Phe,1/1,\N,Unknown significance,\N,missense_variant,18.61,\N,\N,TSPEAR
508428,21:46000180:G>A,NM_198694.2:c.276C>T,NP_941967.2:p.Val92=,1/1,\N,Unknown significance,\N,synonymous_variant,0.741,0.000115554,EXAC_EAS_AF,TSPEAR
508429,21:46000182:C>T,NM_198694.2:c.274G>A,NP_941967.2:p.Val92Ile,1/1,\N,Likely benign,\N,missense_variant,5.715,0.0000150114,EXAC_NFE_AF,TSPEAR
508430,21:46000183:G>A,NM_198694.2:c.273C>T,NP_941967.2:p.Pro91=,1/1,\N,Benign,\N,synonymous_variant,6.336,0.1142,1KG_AFR_AF,TSPEAR
508431,21:46000183:G>T,NM_198694.2:c.273C>A,NP_941967.2:p.Pro91=,1/1,\N,Unknown significance,\N,synonymous_variant,1.281,0.000060562,EXAC_SAS_AF,TSPEAR
508432,21:46000184:G>T,NM_198694.2:c.272C>A,NP_941967.2:p.Pro91His,1/1,\N,Unknown significance,\N,missense_variant,13.49,\N,\N,TSPEAR
508433,21:46000186:C>T,NM_198694.2:c.270G>A,NP_941967.2:p.Val90=,1/1,\N,Benign,\N,synonymous_variant,6.538,0.0416,1KG_AFR_AF,TSPEAR
508434,21:46000188:C>A,NM_198694.2:c.268G>T,NP_941967.2:p.Val90Leu,1/1,\N,Unknown significance,\N,missense_variant,12.18,0.0000150326,EXAC_NFE_AF,TSPEAR
508435,21:46000188:C>T,NM_198694.2:c.268G>A,NP_941967.2:p.Val90Met,1/1,\N,Likely benign,\N,missense_variant,18.18,0.0000863707,EXAC_AMR_AF,TSPEAR
508436,21:46000189:G>A,NM_198694.2:c.267C>T,NP_941967.2:p.Cys89=,1/1,\N,Unknown significance,\N,synonymous_variant,3.855,0.00221239,EXAC_OTH_AF,TSPEAR
508437,21:46000195:G>A,NM_198694.2:c.261C>T,NP_941967.2:p.Ala87=,1/1,\N,Unknown significance,\N,synonymous_variant,0.35,0.0000605694,EXAC_SAS_AF,TSPEAR
508438,21:46000196:G>A,NM_198694.2:c.260C>T,NP_941967.2:p.Ala87Val,1/1,\N,Likely benign,\N,missense_variant,4.512,0.001,1KG_EAS_AF,TSPEAR
508439,21:46000197:C>T,NM_198694.2:c.259G>A,NP_941967.2:p.Ala87Thr,1/1,\N,Likely benign,\N,missense_variant,0.106,0.000347222,EXAC_EAS_AF,TSPEAR
508440,21:46000202:T>G,NM_198694.2:c.254A>C,NP_941967.2:p.Gln85Pro,1/1,\N,Likely benign,\N,missense_variant,0.083,\N,\N,TSPEAR
508441,21:46000203:G>A,NM_198694.2:c.253C>T,NP_941967.2:p.Gln85Ter,1/1,\N,Unknown significance,\N,stop_gained,28.6,0.000101133,EXAC_AFR_AF,TSPEAR
508442,21:46000208:G>A,NM_198694.2:c.248C>T,NP_941967.2:p.Pro83Leu,1/1,\N,Likely benign,\N,missense_variant,4.247,0.001,1KG_EUR_AF,TSPEAR
508443,21:46000209:G>C,NM_198694.2:c.247C>G,NP_941967.2:p.Pro83Ala,1/1,\N,Likely benign,\N,missense_variant,0.002,0.000045144,EXAC_NFE_AF,TSPEAR
508444,21:46000218:C>T,NM_198694.2:c.238G>A,NP_941967.2:p.Ala80Thr,1/1,\N,Likely benign,\N,missense_variant,0.008,0.000454545,EVS_AA_AF,TSPEAR
508445,21:46000219:G>A,NM_198694.2:c.237C>T,NP_941967.2:p.Cys79=,1/1,\N,Unknown significance,\N,synonymous_variant,3.165,0.0014,1KG_AMR_AF,TSPEAR
508446,21:46000223:C>G,NM_198694.2:c.233G>C,NP_941967.2:p.Cys78Ser,1/1,\N,Likely benign,\N,missense_variant,1.19,0.0000150848,EXAC_NFE_AF,TSPEAR
508447,21:46000225:A>G,NM_198694.2:c.231T>C,NP_941967.2:p.Ala77=,1/1,\N,Unknown significance,\N,synonymous_variant,0.06,0.00165045,EXAC_AMR_AF,TSPEAR
508448,21:46000228:C>A,NM_198694.2:c.228G>T,NP_941967.2:p.Pro76=,1/1,\N,Unknown significance,\N,synonymous_variant,11.11,0.0000151089,EXAC_NFE_AF,TSPEAR
508449,21:46000228:C>T,NM_198694.2:c.228G>A,NP_941967.2:p.Pro76=,1/1,\N,Unknown significance,\N,synonymous_variant,10.28,0.000681818,EVS_AA_AF,TSPEAR
508450,21:46000229:G>A,NM_198694.2:c.227C>T,NP_941967.2:p.Pro76Leu,1/1,\N,Unknown significance,\N,missense_variant,15.84,0.000234412,EXAC_EAS_AF,TSPEAR
508451,21:46000239:A>T,NM_198694.2:c.217T>A,NP_941967.2:p.Cys73Ser,1/1,\N,Likely benign,\N,missense_variant,0.045,0.00034877,EXAC_NFE_AF,TSPEAR
508452,21:46000240:C>A,NM_198694.2:c.216G>T,NP_941967.2:p.Ser72=,1/1,\N,Unknown significance,\N,synonymous_variant,12.51,0.0000607755,EXAC_SAS_AF,TSPEAR
508453,21:46000240:C>G,NM_198694.2:c.216G>C,NP_941967.2:p.Ser72=,1/1,\N,Unknown significance,\N,synonymous_variant,8.407,0.0000870474,EXAC_AMR_AF,TSPEAR
508454,21:46000240:C>T,NM_198694.2:c.216G>A,NP_941967.2:p.Ser72=,1/1,\N,Unknown significance,\N,synonymous_variant,11.36,0.000364653,EXAC_SAS_AF,TSPEAR
508455,21:46000241:G>A,NM_198694.2:c.215C>T,NP_941967.2:p.Ser72Leu,1/1,\N,Likely benign,\N,missense_variant,8.789,0.001,1KG_SAS_AF,TSPEAR
508456,21:46000243:G>C,NM_198694.2:c.213C>G,NP_941967.2:p.Pro71=,1/1,\N,Unknown significance,\N,synonymous_variant,0.032,\N,\N,TSPEAR
508457,21:46000244:G>A,NM_198694.2:c.212C>T,NP_941967.2:p.Pro71Leu,1/1,\N,Unknown significance,\N,missense_variant,16.05,0.000581937,EVS_EA_AF,TSPEAR
508458,21:46000244:G>T,NM_198694.2:c.212C>A,NP_941967.2:p.Pro71His,1/1,\N,Unknown significance,\N,missense_variant,12.54,0.0000607755,EXAC_SAS_AF,TSPEAR
508459,21:46000245:G>T,NM_198694.2:c.211C>A,NP_941967.2:p.Pro71Thr,1/1,\N,Unknown significance,\N,missense_variant,11.21,\N,\N,TSPEAR
508460,21:46000246:C>T,NM_198694.2:c.210G>A,NP_941967.2:p.Thr70=,1/1,\N,Unknown significance,\N,synonymous_variant,9.694,0.0000758127,EXAC_NFE_AF,TSPEAR
508461,21:46000247:G>A,NM_198694.2:c.209C>T,NP_941967.2:p.Thr70Met,1/1,\N,Likely benign,\N,missense_variant,0.279,0.000116414,EVS_EA_AF,TSPEAR
508462,21:46000258:G>C,NM_198694.2:c.198C>G,NP_941967.2:p.Thr66=,1/1,\N,Unknown significance,\N,synonymous_variant,0.065,0.0000607755,EXAC_SAS_AF,TSPEAR
508463,21:46000270:T>C,NM_198694.2:c.186A>G,NP_941967.2:p.Gln62=,1/1,\N,Unknown significance,\N,synonymous_variant,0.003,0.0008,1KG_AFR_AF,TSPEAR
508464,21:46000278:G>C,NM_198694.2:c.178C>G,NP_941967.2:p.Pro60Ala,1/1,\N,Likely benign,\N,missense_variant,0.001,\N,\N,TSPEAR
508465,21:46000284:G>A,NM_198694.2:c.172C>T,NP_941967.2:p.Pro58Ser,1/1,\N,Benign,\N,missense_variant,0.001,0.0116268,EXAC_NFE_AF,TSPEAR
508466,21:46000286:TCACAGGCCGCCTGGCAGCAGGGGCTGGACA>T,NM_198694.2:c.140_169del,NP_941967.2:p.Val47_Cys56del,1/1,\N,Unknown significance,\N,inframe_deletion,9.982,\N,\N,TSPEAR
508467,21:46000287:C>T,NM_198694.2:c.169G>A,NP_941967.2:p.Glu57Lys,1/1,\N,Likely benign,\N,missense_variant,6.936,0.0000305885,EXAC_NFE_AF,TSPEAR
508468,21:46000293:C>A,NM_198694.2:c.163G>T,NP_941967.2:p.Ala55Ser,1/1,\N,Likely benign,\N,missense_variant,0.004,0.000108648,EXAC_AFR_AF,TSPEAR
508469,21:46000293:C>T,NM_198694.2:c.163G>A,NP_941967.2:p.Ala55Thr,1/1,\N,Likely benign,\N,missense_variant,0.059,0.0000152868,EXAC_NFE_AF,TSPEAR
508470,21:46000294:C>T,NM_198694.2:c.162G>A,NP_941967.2:p.Ala54=,1/1,\N,Unknown significance,\N,synonymous_variant,12.04,0.00108838,EXAC_AFR_AF,TSPEAR
508471,21:46000295:G>A,NM_198694.2:c.161C>T,NP_941967.2:p.Ala54Val,1/1,\N,Likely benign,\N,missense_variant,0.002,0.000261051,EXAC_AMR_AF,TSPEAR
508472,21:46000297:C>T,NM_198694.2:c.159G>A,NP_941967.2:p.Gln53=,1/1,\N,Unknown significance,\N,synonymous_variant,3.263,0.001,1KG_EUR_AF,TSPEAR
508473,21:46000298:T>G,NM_198694.2:c.158A>C,NP_941967.2:p.Gln53Pro,1/1,\N,Likely benign,\N,missense_variant,0.168,\N,\N,TSPEAR
508474,21:46000305:AG>A,NM_198694.2:c.150del,NP_941967.2:p.Cys51AlafsTer?,1/1,\N,Unknown significance,\N,frameshift_variant,18.75,0.000108578,EXAC_AFR_AF,TSPEAR
508475,21:46000313:G>A,NM_198694.2:c.143C>T,NP_941967.2:p.Ser48Phe,1/1,\N,Likely benign,\N,missense_variant,13.19,0.0000152188,EXAC_NFE_AF,TSPEAR
508476,21:46000314:A>T,NM_198694.2:c.142T>A,NP_941967.2:p.Ser48Thr,1/1,\N,Unknown significance,\N,missense_variant,2.32,0.000060855,EXAC_NFE_AF,TSPEAR
508477,21:46000320:A>G,NM_198694.2:c.136T>C,NP_941967.2:p.Cys46Arg,1/1,\N,Unknown significance,\N,missense_variant,14.93,0.00021363,EXAC_AFR_AF,TSPEAR
508478,21:46000322:C>T,NM_198694.2:c.134G>A,NP_941967.2:p.Ser45Asn,1/1,\N,Likely benign,\N,missense_variant,22.5,0.001,1KG_SAS_AF,TSPEAR
508479,21:46000323:TCAC>T,NM_198694.2:c.130_132del,NP_941967.2:p.Val44del,1/1,\N,Unknown significance,\N,inframe_deletion,17.22,\N,\N,TSPEAR
508480,21:46000327:T>G,NM_198694.2:c.129A>C,NP_941967.2:p.Pro43=,1/1,\N,Unknown significance,\N,synonymous_variant,6.68,0.000227583,EVS_AA_AF,TSPEAR
508481,21:46000327:T>TC,NM_198694.2:c.128_129insG,NP_941967.2:p.Val44SerfsTer14,1/1,\N,Unknown significance,\N,frameshift_variant,27.1,0.0000607977,EXAC_SAS_AF,TSPEAR
508482,21:46000331:G>T,NM_198694.2:c.125C>A,NP_941967.2:p.Thr42Asn,1/1,\N,Unknown significance,\N,missense_variant,14.22,\N,\N,TSPEAR
508483,21:46000338:C>T,NM_198694.2:c.118G>A,NP_941967.2:p.Val40Ile,1/1,\N,Likely benign,\N,missense_variant,11.72,0.0000151277,EXAC_NFE_AF,TSPEAR
508484,21:46000341:G>C,NM_198694.3:c.115C>G,NP_941967.3:p.Leu39Val,1/1,\N,Benign,\N,missense_variant,11.97,0.0287,1KG_AFR_AF,TSPEAR
508485,21:46000343:G>C,NM_198694.2:c.113C>G,NP_941967.2:p.Thr38Ser,1/1,\N,Likely benign,\N,missense_variant,12.16,0.000116877,EXAC_EAS_AF,TSPEAR
508486,21:46000343:G>T,NM_198694.3:c.113C>A,NP_941967.3:p.Thr38Asn,1/1,\N,Unknown significance,\N,missense_variant,20.9,0.000233754,EXAC_EAS_AF,TSPEAR
508487,21:46000348:G>A,NM_198694.2:c.108C>T,NP_941967.2:p.Cys36=,1/1,\N,Unknown significance,\N,synonymous_variant,1.678,0.0000607903,EXAC_SAS_AF,TSPEAR
508488,21:46000350:AG>A,NM_198694.2:c.105del,NP_941967.2:p.Cys36AlafsTer2,1/1,\N,Unknown significance,\N,frameshift_variant,15.82,0.0000301951,EXAC_NFE_AF,TSPEAR
508489,21:46000352:G>C,NM_198694.2:c.104C>G,NP_941967.2:p.Pro35Arg,1/1,\N,Likely benign,\N,missense_variant,5.252,0.000116577,EXAC_EAS_AF,TSPEAR
508490,21:46000352:G>T,NM_198694.2:c.104C>A,NP_941967.2:p.Pro35His,1/1,\N,Unknown significance,\N,missense_variant,7.483,0.000116333,EVS_EA_AF,TSPEAR
508491,21:46000355:G>A,NM_198694.2:c.101C>T,NP_941967.2:p.Ala34Val,1/1,\N,Likely benign,\N,missense_variant,12.14,0.000015073,EXAC_NFE_AF,TSPEAR
508492,21:46000355:G>T,NM_198694.2:c.101C>A,NP_941967.2:p.Ala34Asp,1/1,\N,Likely benign,\N,missense_variant,3.377,0.0000602918,EXAC_NFE_AF,TSPEAR
508493,21:46000356:C>T,NM_198694.2:c.100G>A,NP_941967.2:p.Ala34Thr,1/1,\N,Likely benign,\N,missense_variant,10.92,0.000233155,EXAC_EAS_AF,TSPEAR
508494,21:46000357:G>A,NM_198694.2:c.99C>T,NP_941967.2:p.Thr33=,1/1,\N,Unknown significance,\N,synonymous_variant,7.961,0.000182282,EXAC_SAS_AF,TSPEAR
508495,21:46000358:G>A,NM_198694.2:c.98C>T,NP_941967.2:p.Thr33Ile,1/1,\N,Likely benign,\N,missense_variant,3.178,0.001,1KG_EAS_AF,TSPEAR
508496,21:46000362:C>T,NM_198694.2:c.94G>A,NP_941967.2:p.Gly32Ser,1/1,\N,Likely benign,\N,missense_variant,16.78,0.000116442,EXAC_EAS_AF,TSPEAR
508497,21:46000363:G>A,NM_198694.2:c.93C>T,NP_941967.2:p.Cys31=,1/1,\N,Benign,\N,synonymous_variant,6.193,0.0083,1KG_AFR_AF,TSPEAR
508498,21:46000365:AG>A,NM_198694.2:c.90del,NP_941967.2:p.Cys31AlafsTer7,1/1,\N,Unknown significance,\N,frameshift_variant,23.7,0.0000150317,EXAC_NFE_AF,TSPEAR
508499,21:46000367:G>C,NM_198694.2:c.89C>G,NP_941967.2:p.Pro30Arg,1/1,\N,Unknown significance,\N,missense_variant,11.43,0.000432751,EXAC_AMR_AF,TSPEAR
508500,21:46000367:G>T,NM_198694.2:c.89C>A,NP_941967.2:p.Pro30His,1/1,\N,Benign,\N,missense_variant,12.47,0.0429269,EVS_EA_AF,TSPEAR
508501,21:46000368:G>A,NM_198694.2:c.88C>T,NP_941967.2:p.Pro30Ser,1/1,\N,Likely benign,\N,missense_variant,0.423,0.0008,1KG_AFR_AF,TSPEAR
508502,21:46000370:G>A,NM_198694.2:c.86C>T,NP_941967.2:p.Pro29Leu,1/1,\N,Unknown significance,\N,missense_variant,21.7,0.001,1KG_EAS_AF,TSPEAR
508503,21:46000370:G>T,NM_198694.2:c.86C>A,NP_941967.2:p.Pro29His,1/1,\N,Unknown significance,\N,missense_variant,19.12,0.0000150164,EXAC_NFE_AF,TSPEAR
508504,21:46000371:G>C,NM_198694.2:c.85C>G,NP_941967.2:p.Pro29Ala,1/1,\N,Unknown significance,\N,missense_variant,14.87,0.0000865052,EXAC_AMR_AF,TSPEAR
508505,21:46000382:C>G,NM_198694.2:c.74G>C,NP_941967.2:p.Ser25Thr,1/1,\N,Unknown significance,\N,missense_variant,12.35,0.000302725,EXAC_AFR_AF,TSPEAR
508506,21:46000389:G>A,NM_198694.2:c.67C>T,NP_941967.2:p.Pro23Ser,1/1,\N,Unknown significance,\N,missense_variant,20.7,0.0000149966,EXAC_NFE_AF,TSPEAR
508507,21:46000396:G>A,NM_198694.2:c.60C>T,NP_941967.2:p.Asp20=,1/1,\N,Unknown significance,\N,synonymous_variant,2.946,0.00015124,EXAC_FIN_AF,TSPEAR
508508,21:46000398:C>T,NM_198694.2:c.58G>A,NP_941967.2:p.Asp20Asn,1/1,\N,Benign,\N,missense_variant,22.3,0.533627,EXAC_AMR_AF,TSPEAR
508509,21:46000402:T>C,NM_198694.2:c.54A>G,NP_941967.2:p.Arg18=,1/1,\N,Unknown significance,\N,synonymous_variant,0.024,0.0023,1KG_AFR_AF,TSPEAR
508510,21:46000403:C>T,NM_198694.2:c.53G>A,NP_941967.2:p.Arg18Gln,1/1,\N,Likely benign,\N,missense_variant,7.414,0.0000613121,EXAC_SAS_AF,TSPEAR
508511,21:46000404:G>A,NM_198694.2:c.52C>T,NP_941967.2:p.Arg18Ter,1/1,\N,Unknown significance,\N,stop_gained,34,0.001,1KG_EUR_AF,TSPEAR
508512,21:46000404:G>C,NM_198694.2:c.52C>G,NP_941967.2:p.Arg18Gly,1/1,\N,Unknown significance,\N,missense_variant,20.2,0.000300075,EXAC_NFE_AF,TSPEAR
508513,21:46000404:G>T,NM_198694.2:c.52C>A,NP_941967.2:p.Arg18=,1/1,\N,Unknown significance,\N,synonymous_variant,5.235,0.0000150038,EXAC_NFE_AF,TSPEAR
508514,21:46000411:G>A,NM_198694.2:c.45C>T,NP_941967.2:p.Asp15=,1/1,\N,Unknown significance,\N,synonymous_variant,0.105,\N,\N,TSPEAR
508515,21:46000414:A>G,NM_198694.2:c.42T>C,NP_941967.2:p.Ser14=,1/1,\N,Benign,\N,synonymous_variant,0.051,0.1142,1KG_AFR_AF,TSPEAR
508516,21:46000421:G>A,NM_198694.2:c.35C>T,NP_941967.2:p.Ala12Val,1/1,\N,Likely benign,\N,missense_variant,11.57,0.0000150421,EXAC_NFE_AF,TSPEAR
508517,21:46000422:C>T,NM_198694.2:c.34G>A,NP_941967.2:p.Ala12Thr,1/1,\N,Likely benign,\N,missense_variant,9.267,0.000116279,EVS_EA_AF,TSPEAR
508518,21:46000423:G>A,NM_198694.2:c.33C>T,NP_941967.2:p.Ser11=,1/1,\N,Unknown significance,\N,synonymous_variant,9.625,0.001,1KG_EUR_AF,TSPEAR
508519,21:46000424:C>T,NM_198694.2:c.32G>A,NP_941967.2:p.Ser11Asn,1/1,\N,Likely benign,\N,missense_variant,16.8,0.001,1KG_SAS_AF,TSPEAR
508520,21:46000428:A>G,NM_198694.2:c.28T>C,NP_941967.2:p.Ser10Pro,1/1,\N,Unknown significance,\N,missense_variant,22.7,0.0000150775,EXAC_NFE_AF,TSPEAR
508521,21:46000434:C>T,NM_198694.2:c.22G>A,NP_941967.2:p.Val8Ile,1/1,\N,Unknown significance,\N,missense_variant,15.27,0.000136034,EXAC_NFE_AF,TSPEAR
508522,21:46000439:A>G,NM_198694.2:c.17T>C,NP_941967.2:p.Met6Thr,1/1,\N,Likely benign,\N,missense_variant,0.104,0.003,1KG_AFR_AF,TSPEAR
508523,21:46000445:C>G,NM_198694.2:c.11G>C,NP_941967.2:p.Cys4Ser,1/1,\N,Benign,\N,missense_variant,0.002,0.1142,1KG_AFR_AF,TSPEAR
508524,21:46000447:C>T,NM_198694.2:c.9G>A,NP_941967.2:p.Ala3=,1/1,\N,Unknown significance,\N,synonymous_variant,11.82,0.000454133,EVS_AA_AF,TSPEAR
508525,21:46000448:G>A,NM_198694.2:c.8C>T,NP_941967.2:p.Ala3Val,1/1,\N,Likely benign,\N,missense_variant,16.62,0.000116279,EVS_EA_AF,TSPEAR
508526,21:46000449:C>T,NM_198694.2:c.7G>A,NP_941967.2:p.Ala3Thr,1/1,\N,Benign,\N,missense_variant,8.291,0.0061,1KG_AFR_AF,TSPEAR
508527,21:46000450:G>A,NM_198694.2:c.6C>T,NP_941967.2:p.Ala2=,1/1,\N,Unknown significance,\N,synonymous_variant,8.46,0.001,1KG_EAS_AF|1KG_SAS_AF,TSPEAR
508528,21:46000455:T>A,NM_198694.2:c.1A>T,NP_941967.2:p.Met1?,1/1,\N,Likely benign,\N,start_lost,7.67,0.0000152616,EXAC_NFE_AF,TSPEAR
508529,21:46000455:T>G,NM_198694.2:c.1A>C,NP_941967.2:p.Met1?,1/1,\N,Likely benign,\N,start_lost,5.918,0.0000152616,EXAC_NFE_AF,TSPEAR
508530,21:46000456:G>A,NM_198694.2:c.-1C>T,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,10.72,0.000116279,EVS_EA_AF,TSPEAR
508531,21:46000467:G>A,NM_198694.2:c.-12C>T,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,9.258,0.000085034,EXAC_SAS_AF,TSPEAR
508532,21:46000472:C>G,NM_198694.2:c.-17G>C,\N,1/1,\N,Benign,\N,5_prime_UTR_variant,9.541,0.1142,1KG_AFR_AF,TSPEAR
508533,21:46000472:C>T,NM_198694.2:c.-17G>A,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,11.17,0.0000997606,EXAC_AFR_AF,TSPEAR
508534,21:46000473:G>A,NM_198694.2:c.-18C>T,\N,1/1,\N,Unknown significance,\N,5_prime_UTR_variant,10.56,0.0014,1KG_AMR_AF,TSPEAR
508535,21:46000489:G>A,NM_144991.2:c.83-12600C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,5.692,0.000116279,EVS_EA_AF,TSPEAR
508536,21:46000491:G>C,NM_144991.2:c.83-12602C>G,\N,\N,1/11,Unknown significance,\N,intron_variant,2.194,0.00118413,EXAC_SAS_AF,TSPEAR
508537,21:46000493:GGTGTGAGTGAGTGAGT>G,NM_144991.2:c.83-12620_83-12605del,\N,\N,1/11,Unknown significance,\N,intron_variant,5.326,\N,\N,TSPEAR
508538,21:46000495:TGTGA>T,NM_144991.2:c.83-12610_83-12607del,\N,\N,1/11,Unknown significance,\N,intron_variant,6.417,\N,\N,TSPEAR
508539,21:46000505:TGA>T,NM_144991.2:c.83-12618_83-12617del,\N,\N,1/11,Unknown significance,\N,intron_variant,6.696,\N,\N,TSPEAR
508540,21:46000506:G>A,NM_144991.2:c.83-12617C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,6.313,0.0000155618,EXAC_NFE_AF,TSPEAR
508541,21:46000508:G>A,NM_144991.2:c.83-12619C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.205,\N,\N,TSPEAR
508542,21:46000521:TGAAG>T,NM_144991.2:c.83-12636_83-12633del,\N,\N,1/11,Benign,\N,intron_variant,7.137,0.1036,1KG_AFR_AF,TSPEAR
508543,21:46000524:A>G,NM_144991.2:c.83-12635T>C,\N,\N,1/11,Benign,\N,intron_variant,2.978,0.0106,1KG_AFR_AF,TSPEAR
508544,21:46000529:GGAGT>G,NM_144991.2:c.83-12644_83-12641del,\N,\N,1/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
508545,21:46000533:T>G,NM_144991.2:c.83-12644A>C,\N,\N,1/11,Benign,\N,intron_variant,0.211,0.1059,1KG_AFR_AF,TSPEAR
508546,21:46000576:C>T,NM_144991.2:c.83-12687G>A,\N,\N,1/11,Benign,\N,intron_variant,5.279,0.0098,1KG_AFR_AF,TSPEAR
508547,21:46000583:G>A,NM_144991.2:c.83-12694C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.263,0,1KG_ALL_AF|1KG_AFR_AF|1KG_AMR_AF|1KG_EAS_AF|1KG_EUR_AF|1KG_SAS_AF,TSPEAR
508548,21:46000594:T>C,NM_144991.2:c.83-12705A>G,\N,\N,1/11,Benign,\N,intron_variant,0.043,0.2504,1KG_AFR_AF,TSPEAR
508549,21:46000601:A>G,NM_144991.2:c.83-12712T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,8.78,0.001,1KG_EAS_AF,TSPEAR
508550,21:46000629:G>A,NM_144991.2:c.83-12740C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,13.89,0.0015,1KG_AFR_AF,TSPEAR
508551,21:46000656:G>A,NM_144991.2:c.83-12767C>T,\N,\N,1/11,Benign,\N,intron_variant,0.289,0.0537,1KG_AFR_AF,TSPEAR
508552,21:46000703:G>A,NM_144991.2:c.83-12814C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,8.521,0.0008,1KG_AFR_AF,TSPEAR
508553,21:46000720:G>A,NM_144991.2:c.83-12831C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.306,\N,\N,TSPEAR
508554,21:46000721:T>C,NM_144991.2:c.83-12832A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,3.756,0.001,1KG_EAS_AF,TSPEAR
508555,21:46000732:C>T,NM_144991.2:c.83-12843G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,4.653,0.001,1KG_EUR_AF,TSPEAR
508556,21:46000733:G>A,NM_144991.2:c.83-12844C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.235,0.001,1KG_EUR_AF,TSPEAR
508557,21:46000741:T>C,NM_144991.2:c.83-12852A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.95,\N,\N,TSPEAR
508558,21:46000784:T>C,NM_144991.2:c.83-12895A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,1.087,0.001,1KG_EUR_AF,TSPEAR
508559,21:46000808:G>A,NM_144991.2:c.83-12919C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,5.271,\N,\N,TSPEAR
508560,21:46000884:T>G,NM_144991.2:c.83-12995A>C,\N,\N,1/11,Unknown significance,\N,intron_variant,9.963,\N,\N,TSPEAR
508561,21:46000918:A>G,NM_144991.2:c.83-13029T>C,\N,\N,1/11,Benign,\N,intron_variant,0.63,0.2156,1KG_AFR_AF,TSPEAR
508562,21:46000921:T>C,NM_144991.2:c.83-13032A>G,\N,\N,1/11,Benign,\N,intron_variant,0.945,0.0121,1KG_AFR_AF,TSPEAR
508563,21:46000954:A>G,NM_144991.2:c.83-13065T>C,\N,\N,1/11,Benign,\N,intron_variant,0.143,0.9145,1KG_AFR_AF,TSPEAR
508564,21:46000965:G>A,NM_144991.2:c.83-13076C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,6.852,\N,\N,TSPEAR
508565,21:46000970:C>T,NM_144991.2:c.83-13081G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,6.766,0.001,1KG_EAS_AF,TSPEAR
508566,21:46000989:G>A,NM_144991.2:c.83-13100C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,7.577,\N,\N,TSPEAR
508567,21:46000994:G>A,NM_144991.2:c.83-13105C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,6.693,\N,\N,TSPEAR
508568,21:46001004:T>A,NM_144991.2:c.83-13115A>T,\N,\N,1/11,Benign,\N,intron_variant,5.726,0.1142,1KG_AFR_AF,TSPEAR
508569,21:46001004:T>G,NM_144991.2:c.83-13115A>C,\N,\N,1/11,Benign,\N,intron_variant,3.294,0.0136,1KG_AFR_AF,TSPEAR
508570,21:46001016:T>C,NM_144991.2:c.83-13127A>G,\N,\N,1/11,Benign,\N,intron_variant,1.407,0.1142,1KG_AFR_AF,TSPEAR
508571,21:46001033:G>A,NM_144991.2:c.83-13144C>T,\N,\N,1/11,Benign,\N,intron_variant,0.497,0.0673,1KG_AFR_AF,TSPEAR
508572,21:46001036:C>T,NM_144991.2:c.83-13147G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,2.634,0.001,1KG_EAS_AF,TSPEAR
508573,21:46001054:A>T,NM_144991.2:c.83-13165T>A,\N,\N,1/11,Unknown significance,\N,intron_variant,2.981,0.001,1KG_EAS_AF,TSPEAR
508574,21:46001095:T>A,NM_144991.2:c.83-13206A>T,\N,\N,1/11,Benign,\N,intron_variant,2.475,0.4478,1KG_AFR_AF,TSPEAR
508575,21:46001104:C>T,NM_144991.2:c.83-13215G>A,\N,\N,1/11,Benign,\N,intron_variant,0.35,0.115,1KG_AFR_AF,TSPEAR
508576,21:46001109:T>A,NM_144991.2:c.83-13220A>T,\N,\N,1/11,Unknown significance,\N,intron_variant,5.988,\N,\N,TSPEAR
508577,21:46001212:T>G,NM_144991.2:c.83-13323A>C,\N,\N,1/11,Benign,\N,intron_variant,5.124,0.0068,1KG_AFR_AF,TSPEAR
508578,21:46001237:A>G,NM_144991.2:c.83-13348T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,3.199,0.001,1KG_EUR_AF,TSPEAR
508579,21:46001250:G>A,NM_144991.2:c.83-13361C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,2.608,\N,\N,TSPEAR
508580,21:46001255:G>T,NM_144991.2:c.83-13366C>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.076,0.001,1KG_EUR_AF,TSPEAR
508581,21:46001259:A>C,NM_144991.2:c.83-13370T>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.439,\N,\N,TSPEAR
508582,21:46001286:T>C,NM_144991.2:c.83-13397A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,4.566,0.0008,1KG_AFR_AF,TSPEAR
508583,21:46001290:A>G,NM_144991.2:c.83-13401T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,4.88,\N,\N,TSPEAR
508584,21:46001301:C>CA,NM_144991.2:c.83-13413dup,\N,\N,1/11,Unknown significance,\N,intron_variant,\N,0.003,1KG_EAS_AF,TSPEAR
508585,21:46001330:C>A,NM_144991.2:c.83-13441G>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.436,0.0023,1KG_AFR_AF,TSPEAR
508586,21:46001360:C>T,NM_144991.2:c.83-13471G>A,\N,\N,1/11,Benign,\N,intron_variant,1.254,0.1135,1KG_AFR_AF,TSPEAR
508587,21:46001361:G>A,NM_144991.2:c.83-13472C>T,\N,\N,1/11,Benign,\N,intron_variant,0.713,0.0651,1KG_AFR_AF,TSPEAR
508588,21:46001407:TTGTC>T,NM_144991.2:c.83-13522_83-13519del,\N,\N,1/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
508589,21:46001408:T>G,NM_144991.2:c.83-13519A>C,\N,\N,1/11,Unknown significance,\N,intron_variant,4.617,0.003,1KG_AFR_AF,TSPEAR
508590,21:46001423:G>A,NM_144991.2:c.83-13534C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.384,0.001,1KG_SAS_AF,TSPEAR
508591,21:46001443:T>C,NM_144991.2:c.83-13554A>G,\N,\N,1/11,Benign,\N,intron_variant,3.626,0.0265,1KG_AFR_AF,TSPEAR
508592,21:46001466:T>C,NM_144991.2:c.83-13577A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,1.59,\N,\N,TSPEAR
508593,21:46001476:G>A,NM_144991.2:c.83-13587C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.919,0.0008,1KG_AFR_AF,TSPEAR
508594,21:46001478:G>A,NM_144991.2:c.83-13589C>T,\N,\N,1/11,Benign,\N,intron_variant,1.555,0.1135,1KG_AFR_AF,TSPEAR
508595,21:46001506:G>A,NM_144991.2:c.83-13617C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,7.032,\N,\N,TSPEAR
508596,21:46001536:C>T,NM_144991.2:c.83-13647G>A,\N,\N,1/11,Benign,\N,intron_variant,7.077,0.1135,1KG_AFR_AF,TSPEAR
508597,21:46001550:C>T,NM_144991.2:c.83-13661G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,3.48,0.0043,1KG_AMR_AF,TSPEAR
508598,21:46001567:CTT>C,NM_144991.2:c.83-13680_83-13679del,\N,\N,1/11,Benign,\N,intron_variant,3.309,0.0556,1KG_EAS_AF,TSPEAR
508599,21:46001577:A>G,NM_144991.2:c.83-13688T>C,\N,\N,1/11,Benign,\N,intron_variant,1.158,0.1135,1KG_AFR_AF,TSPEAR
508600,21:46001587:C>G,NM_144991.2:c.83-13698G>C,\N,\N,1/11,Unknown significance,\N,intron_variant,4.256,0.0008,1KG_AFR_AF,TSPEAR
508601,21:46001588:T>C,NM_144991.2:c.83-13699A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.944,0.0008,1KG_AFR_AF,TSPEAR
508602,21:46001592:G>T,NM_144991.2:c.83-13703C>A,\N,\N,1/11,Unknown significance,\N,intron_variant,3.023,0.001,1KG_SAS_AF,TSPEAR
508603,21:46001595:A>G,NM_144991.2:c.83-13706T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,5.379,0.0008,1KG_AFR_AF,TSPEAR
508604,21:46001600:A>G,NM_144991.2:c.83-13711T>C,\N,\N,1/11,Benign,\N,intron_variant,4.43,0.1135,1KG_AFR_AF,TSPEAR
508605,21:46001608:C>G,NM_144991.2:c.83-13719G>C,\N,\N,1/11,Unknown significance,\N,intron_variant,0.784,\N,\N,TSPEAR
508606,21:46001612:C>T,NM_144991.2:c.83-13723G>A,\N,\N,1/11,Benign,\N,intron_variant,1.131,0.005,1KG_EUR_AF,TSPEAR
508607,21:46001626:C>T,NM_144991.2:c.83-13737G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.89,0.001,1KG_EAS_AF,TSPEAR
508608,21:46001644:A>AT,NM_144991.2:c.83-13756dup,\N,\N,1/11,Unknown significance,\N,intron_variant,0.338,\N,\N,TSPEAR
508609,21:46001662:T>C,NM_144991.2:c.83-13773A>G,\N,\N,1/11,Benign,\N,intron_variant,1.291,0.006,1KG_EAS_AF,TSPEAR
508610,21:46001669:G>T,NM_144991.2:c.83-13780C>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.191,0.0008,1KG_AFR_AF,TSPEAR
508611,21:46001678:C>T,NM_144991.2:c.83-13789G>A,\N,\N,1/11,Benign,\N,intron_variant,5.195,0.1135,1KG_AFR_AF,TSPEAR
508612,21:46001680:C>T,NM_144991.2:c.83-13791G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,4.186,0.0015,1KG_AFR_AF,TSPEAR
508613,21:46001698:T>C,NM_144991.2:c.83-13809A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,11.3,\N,\N,TSPEAR
508614,21:46001719:C>T,NM_144991.2:c.83-13830G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,10.28,0.0031,1KG_SAS_AF,TSPEAR
508615,21:46001843:G>A,NM_144991.2:c.83-13954C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.712,0.0014,1KG_AMR_AF,TSPEAR
508616,21:46001861:G>T,NM_144991.2:c.83-13972C>A,\N,\N,1/11,Benign,\N,intron_variant,0.438,0.0219,1KG_AFR_AF,TSPEAR
508617,21:46001863:C>T,NM_144991.2:c.83-13974G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,1.075,0.0043,1KG_AMR_AF,TSPEAR
508618,21:46001870:G>T,NM_144991.2:c.83-13981C>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.584,\N,\N,TSPEAR
508619,21:46001888:T>C,NM_144991.2:c.83-13999A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.264,0.001,1KG_SAS_AF,TSPEAR
508620,21:46001907:T>C,NM_144991.2:c.83-14018A>G,\N,\N,1/11,Benign,\N,intron_variant,1.136,0.0287,1KG_AFR_AF,TSPEAR
508621,21:46001909:A>G,NM_144991.2:c.83-14020T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,2.85,\N,\N,TSPEAR
508622,21:46001923:T>C,NM_144991.2:c.83-14034A>G,\N,\N,1/11,Benign,\N,intron_variant,1.186,0.0825,1KG_AFR_AF,TSPEAR
508623,21:46002008:G>A,NM_144991.2:c.83-14119C>T,\N,\N,1/11,Benign,\N,intron_variant,2.465,0.0113,1KG_AFR_AF,TSPEAR
508624,21:46002018:C>T,NM_144991.2:c.83-14129G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,6.152,\N,\N,TSPEAR
508625,21:46002019:G>A,NM_144991.2:c.83-14130C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.303,0.0043,1KG_AMR_AF,TSPEAR
508626,21:46002021:C>A,NM_144991.2:c.83-14132G>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.582,\N,\N,TSPEAR
508627,21:46002030:G>A,NM_144991.2:c.83-14141C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.806,\N,\N,TSPEAR
508628,21:46002039:A>G,NM_144991.2:c.83-14150T>C,\N,\N,1/11,Benign,\N,intron_variant,0.561,0.0159,1KG_EAS_AF,TSPEAR
508629,21:46002054:G>A,NM_144991.2:c.83-14165C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.179,0.001,1KG_EAS_AF,TSPEAR
508630,21:46002081:G>A,NM_144991.2:c.83-14192C>T,\N,\N,1/11,Benign,\N,intron_variant,1.803,0.0144,1KG_AFR_AF,TSPEAR
508631,21:46002082:C>T,NM_144991.2:c.83-14193G>A,\N,\N,1/11,Benign,\N,intron_variant,4.139,0.1142,1KG_AFR_AF,TSPEAR
508632,21:46002088:T>G,NM_144991.2:c.83-14199A>C,\N,\N,1/11,Benign,\N,intron_variant,2.428,0.2156,1KG_AFR_AF,TSPEAR
508633,21:46002095:T>C,NM_144991.2:c.83-14206A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.774,\N,\N,TSPEAR
508634,21:46002136:A>AT,NM_144991.2:c.83-14248dup,\N,\N,1/11,Benign,\N,intron_variant,0.039,0.0287,1KG_AFR_AF,TSPEAR
508635,21:46002161:T>C,NM_144991.2:c.83-14272A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.452,\N,\N,TSPEAR
508636,21:46002166:A>G,NM_144991.2:c.83-14277T>C,\N,\N,1/11,Benign,\N,intron_variant,0.037,0.202,1KG_AFR_AF,TSPEAR
508637,21:46002168:C>G,NM_144991.2:c.83-14279G>C,\N,\N,1/11,Unknown significance,\N,intron_variant,0.518,\N,\N,TSPEAR
508638,21:46002185:G>A,NM_144991.2:c.83-14296C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.177,0.002,1KG_SAS_AF,TSPEAR
508639,21:46002190:C>A,NM_144991.2:c.83-14301G>T,\N,\N,1/11,Benign,\N,intron_variant,2.611,0.0439,1KG_AFR_AF,TSPEAR
508640,21:46002210:C>G,NM_144991.2:c.83-14321G>C,\N,\N,1/11,Benign,\N,intron_variant,0.324,0.8865,1KG_AFR_AF,TSPEAR
508641,21:46002211:G>A,NM_144991.2:c.83-14322C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.312,0.002,1KG_SAS_AF,TSPEAR
508642,21:46002217:C>A,NM_144991.2:c.83-14328G>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.042,\N,\N,TSPEAR
508643,21:46002225:C>T,NM_144991.2:c.83-14336G>A,\N,\N,1/11,Benign,\N,intron_variant,1.106,0.1142,1KG_AFR_AF,TSPEAR
508644,21:46002230:T>C,NM_144991.2:c.83-14341A>G,\N,\N,1/11,Benign,\N,intron_variant,0.108,0.1142,1KG_AFR_AF,TSPEAR
508645,21:46002254:C>T,NM_144991.2:c.83-14365G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,3.196,0.0008,1KG_AFR_AF,TSPEAR
508646,21:46002282:G>C,NM_144991.2:c.83-14393C>G,\N,\N,1/11,Benign,\N,intron_variant,0.459,0.2113,1KG_EAS_AF,TSPEAR
508647,21:46002295:G>T,NM_144991.2:c.83-14406C>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.358,0.001,1KG_SAS_AF,TSPEAR
508648,21:46002301:G>A,NM_144991.2:c.83-14412C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.766,\N,\N,TSPEAR
508649,21:46002330:G>A,NM_144991.2:c.83-14441C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.587,0.001,1KG_EUR_AF,TSPEAR
508650,21:46002374:A>G,NM_144991.2:c.83-14485T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,3.171,0.0043,1KG_AMR_AF,TSPEAR
508651,21:46002412:G>A,NM_144991.2:c.83-14523C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,2.134,0.001,1KG_EAS_AF,TSPEAR
508652,21:46002467:TCTC>T,NM_144991.2:c.83-14581_83-14579del,\N,\N,1/11,Benign,\N,intron_variant,6.892,0.0242,1KG_AFR_AF,TSPEAR
508653,21:46002470:C>T,NM_144991.2:c.83-14581G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,6.864,0.0014,1KG_AMR_AF,TSPEAR
508654,21:46002475:T>C,NM_144991.2:c.83-14586A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.535,\N,\N,TSPEAR
508655,21:46002527:C>T,NM_144991.2:c.83-14638G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,3.367,\N,\N,TSPEAR
508656,21:46002528:C>T,NM_144991.2:c.83-14639G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,4.977,\N,\N,TSPEAR
508657,21:46002544:A>G,NM_144991.2:c.83-14655T>C,\N,\N,1/11,Benign,\N,intron_variant,0.032,0.1964,1KG_EAS_AF,TSPEAR
508658,21:46002551:T>C,NM_144991.2:c.83-14662A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,1.204,0.001,1KG_EAS_AF|1KG_SAS_AF,TSPEAR
508659,21:46002556:C>T,NM_144991.2:c.83-14667G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,2.8,0.001,1KG_SAS_AF,TSPEAR
508660,21:46002558:G>A,NM_144991.2:c.83-14669C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.645,\N,\N,TSPEAR
508661,21:46002570:C>T,NM_144991.2:c.83-14681G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,1.217,\N,\N,TSPEAR
508662,21:46002571:G>A,NM_144991.2:c.83-14682C>T,\N,\N,1/11,Benign,\N,intron_variant,0.226,0.0219,1KG_AFR_AF,TSPEAR
508663,21:46002577:C>T,NM_144991.2:c.83-14688G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,3.452,0.0041,1KG_SAS_AF,TSPEAR
508664,21:46002582:A>T,NM_144991.2:c.83-14693T>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.053,\N,\N,TSPEAR
508665,21:46002609:G>A,NM_144991.2:c.83-14720C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.683,0.003,1KG_EUR_AF,TSPEAR
508666,21:46002611:A>C,NM_144991.2:c.83-14722T>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.203,\N,\N,TSPEAR
508667,21:46002645:G>A,NM_144991.2:c.83-14756C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.051,0.0014,1KG_AMR_AF,TSPEAR
508668,21:46002669:TTCTTTCTTTCTC>T,NM_144991.2:c.83-14792_83-14781del,\N,\N,1/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
508669,21:46002675:C>A,NM_144991.2:c.83-14786G>T,\N,\N,1/11,Benign,\N,intron_variant,0.259,0.0328,1KG_EUR_AF,TSPEAR
508670,21:46002681:C>T,NM_144991.2:c.83-14792G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.119,\N,\N,TSPEAR
508671,21:46002681:CTCTT>C,NM_144991.2:c.83-14796_83-14793del,\N,\N,1/11,Unknown significance,\N,intron_variant,2.254,0.0041,1KG_SAS_AF,TSPEAR
508672,21:46002684:T>C,NM_144991.2:c.83-14795A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.209,\N,\N,TSPEAR
508673,21:46002685:T>C,NM_144991.2:c.83-14796A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.366,\N,\N,TSPEAR
508674,21:46002691:CTCTT>C,NM_144991.2:c.83-14806_83-14803del,\N,\N,1/11,Benign,\N,intron_variant,2.225,0.0567,1KG_AFR_AF,TSPEAR
508675,21:46002693:C>T,NM_144991.2:c.83-14804G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.881,\N,\N,TSPEAR
508676,21:46002694:T>G,NM_144991.2:c.83-14805A>C,\N,\N,1/11,Unknown significance,\N,intron_variant,0.36,0.0014,1KG_AMR_AF,TSPEAR
508677,21:46002695:T>C,NM_144991.2:c.83-14806A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.357,\N,\N,TSPEAR
508678,21:46002710:CTTCT>C,NM_144991.2:c.83-14825_83-14822del,\N,\N,1/11,Unknown significance,\N,intron_variant,0.941,\N,\N,TSPEAR
508679,21:46002711:T>A,NM_144991.2:c.83-14822A>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.154,\N,\N,TSPEAR
508680,21:46002717:CTTTCT>C,NM_144991.2:c.83-14833_83-14829del,\N,\N,1/11,Benign,\N,intron_variant,0.961,0.1964,1KG_EAS_AF,TSPEAR
508681,21:46002722:T>TTTTCTTCCTTCTTTC,NM_144991.2:c.83-14834_83-14833insGAAAGAAGGAAGAAA,\N,\N,1/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
508682,21:46002742:C>G,NM_144991.2:c.83-14853G>C,\N,\N,1/11,Unknown significance,\N,intron_variant,1.743,\N,\N,TSPEAR
508683,21:46002744:T>C,NM_144991.2:c.83-14855A>G,\N,\N,1/11,Benign,\N,intron_variant,2.008,0.1964,1KG_EAS_AF,TSPEAR
508684,21:46002772:T>G,NM_144991.2:c.83-14883A>C,\N,\N,1/11,Unknown significance,\N,intron_variant,4.777,\N,\N,TSPEAR
508685,21:46002787:G>T,NM_144991.2:c.83-14898C>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.667,0.0015,1KG_AFR_AF,TSPEAR
508686,21:46002789:C>A,NM_144991.2:c.83-14900G>T,\N,\N,1/11,Unknown significance,\N,intron_variant,2.403,0.001,1KG_EUR_AF,TSPEAR
508687,21:46002791:C>T,NM_144991.2:c.83-14902G>A,\N,\N,1/11,Benign,\N,intron_variant,0.179,0.0053,1KG_AFR_AF,TSPEAR
508688,21:46002799:C>T,NM_144991.2:c.83-14910G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,1.768,0.001,1KG_EAS_AF,TSPEAR
508689,21:46002800:G>A,NM_144991.2:c.83-14911C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.181,\N,\N,TSPEAR
508690,21:46002832:G>A,NM_144991.2:c.83-14943C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,1.514,0.0023,1KG_AFR_AF,TSPEAR
508691,21:46002833:A>T,NM_144991.2:c.83-14944T>A,\N,\N,1/11,Unknown significance,\N,intron_variant,1.539,\N,\N,TSPEAR
508692,21:46002838:C>T,NM_144991.2:c.83-14949G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,2.451,0.001,1KG_SAS_AF,TSPEAR
508693,21:46002840:G>A,NM_144991.2:c.83-14951C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.014,0.0023,1KG_AFR_AF,TSPEAR
508694,21:46002849:G>A,NM_144991.2:c.83-14960C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,2.531,0.0008,1KG_AFR_AF,TSPEAR
508695,21:46002854:G>C,NM_144991.2:c.83-14965C>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.269,\N,\N,TSPEAR
508696,21:46002855:T>C,NM_144991.2:c.83-14966A>G,\N,\N,1/11,Benign,\N,intron_variant,0.065,0.1964,1KG_EAS_AF,TSPEAR
508697,21:46002855:TG>CA,NM_144991.2:c.83-14967_83-14966inv,\N,\N,1/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
508698,21:46002856:G>A,NM_144991.2:c.83-14967C>T,\N,\N,1/11,Benign,\N,intron_variant,0.146,0.1964,1KG_EAS_AF,TSPEAR
508699,21:46002864:A>G,NM_144991.2:c.83-14975T>C,\N,\N,1/11,Benign,\N,intron_variant,2.235,0.0051,1KG_SAS_AF,TSPEAR
508700,21:46002874:TTTTC>T,NM_144991.2:c.83-14989_83-14986del,\N,\N,1/11,Unknown significance,\N,intron_variant,2.877,\N,\N,TSPEAR
508701,21:46002881:T>C,NM_144991.2:c.83-14992A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.88,\N,\N,TSPEAR
508702,21:46002883:T>C,NM_144991.2:c.83-14994A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.397,\N,\N,TSPEAR
508703,21:46002886:C>CT,NM_144991.2:c.83-14998dup,\N,\N,1/11,Benign,\N,intron_variant,2.546,0.1964,1KG_EAS_AF,TSPEAR
508704,21:46002886:CTTTC>T,NM_144991.2:c.83-15001_83-14997delinsA,\N,\N,1/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
508705,21:46002890:C>CT,NM_144991.2:c.83-15002dup,\N,\N,1/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
508706,21:46002890:C>T,NM_144991.2:c.83-15001G>A,\N,\N,1/11,Benign,\N,intron_variant,0.196,0.4062,1KG_AFR_AF,TSPEAR
508707,21:46002890:C>TT,NM_144991.2:c.83-15001delinsAA,\N,\N,1/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
508708,21:46002907:T>C,NM_144991.2:c.83-15018A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.912,\N,\N,TSPEAR
508709,21:46002909:G>C,NM_144991.2:c.83-15020C>G,\N,\N,1/11,Unknown significance,\N,intron_variant,1.721,\N,\N,TSPEAR
508710,21:46002917:G>C,NM_144991.2:c.83-15028C>G,\N,\N,1/11,Unknown significance,\N,intron_variant,2.155,\N,\N,TSPEAR
508711,21:46002923:C>A,NM_144991.2:c.83-15034G>T,\N,\N,1/11,Benign,\N,intron_variant,6.121,0.1964,1KG_EAS_AF,TSPEAR
508712,21:46002923:C>G,NM_144991.2:c.83-15034G>C,\N,\N,1/11,Unknown significance,\N,intron_variant,4.624,\N,\N,TSPEAR
508713,21:46002950:T>C,NM_144991.2:c.83-15061A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,1.633,\N,\N,TSPEAR
508714,21:46002951:G>A,NM_144991.2:c.83-15062C>T,\N,\N,1/11,Benign,\N,intron_variant,2.094,0.1964,1KG_EAS_AF,TSPEAR
508715,21:46002959:A>G,NM_144991.2:c.83-15070T>C,\N,\N,1/11,Benign,\N,intron_variant,0.121,0.0098,1KG_AFR_AF,TSPEAR
508716,21:46002969:T>C,NM_144991.2:c.83-15080A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.572,\N,\N,TSPEAR
508717,21:46002971:T>C,NM_144991.2:c.83-15082A>G,\N,\N,1/11,Benign,\N,intron_variant,0.614,0.4304,1KG_AFR_AF,TSPEAR
508718,21:46002992:C>T,NM_144991.2:c.83-15103G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,1.38,0.0008,1KG_AFR_AF,TSPEAR
508719,21:46003001:C>A,NM_144991.2:c.83-15112G>T,\N,\N,1/11,Unknown significance,\N,intron_variant,4.108,0.0008,1KG_AFR_AF,TSPEAR
508720,21:46003010:G>A,NM_144991.2:c.83-15121C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,8.353,\N,\N,TSPEAR
508721,21:46003019:C>G,NM_144991.2:c.83-15130G>C,\N,\N,1/11,Unknown significance,\N,intron_variant,10.33,0.003,1KG_EAS_AF,TSPEAR
508722,21:46003020:C>T,NM_144991.2:c.83-15131G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,11.41,0.001,1KG_EUR_AF,TSPEAR
508723,21:46003035:C>T,NM_144991.2:c.83-15146G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,11.01,0.0008,1KG_AFR_AF,TSPEAR
508724,21:46003050:G>A,NM_144991.2:c.83-15161C>T,\N,\N,1/11,Benign,\N,intron_variant,7.726,0.0139,1KG_EUR_AF,TSPEAR
508725,21:46003059:C>G,NM_144991.2:c.83-15170G>C,\N,\N,1/11,Unknown significance,\N,intron_variant,7.338,\N,\N,TSPEAR
508726,21:46003071:G>GC,NM_144991.2:c.83-15183dup,\N,\N,1/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
508727,21:46003071:GC>G,NM_144991.2:c.83-15183del,\N,\N,1/11,Benign,\N,intron_variant,5.761,0.1964,1KG_EAS_AF,TSPEAR
508728,21:46003082:C>G,NM_144991.2:c.83-15193G>C,\N,\N,1/11,Unknown significance,\N,intron_variant,4.632,\N,\N,TSPEAR
508729,21:46003100:C>T,NM_144991.2:c.83-15211G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,3.464,\N,\N,TSPEAR
508730,21:46003104:G>A,NM_144991.2:c.83-15215C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,2.277,\N,\N,TSPEAR
508731,21:46003108:G>T,NM_144991.2:c.83-15219C>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.14,0.001,1KG_EUR_AF,TSPEAR
508732,21:46003123:G>A,NM_144991.2:c.83-15234C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,4.563,\N,\N,TSPEAR
508733,21:46003128:G>A,NM_144991.2:c.83-15239C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,4.628,\N,\N,TSPEAR
508734,21:46003146:G>A,NM_144991.2:c.83-15257C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.679,0.001,1KG_SAS_AF,TSPEAR
508735,21:46003156:C>T,NM_144991.2:c.83-15267G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,4.642,0.001,1KG_EUR_AF,TSPEAR
508736,21:46003159:C>T,NM_144991.2:c.83-15270G>A,\N,\N,1/11,Benign,\N,intron_variant,0.553,0.0234,1KG_AFR_AF,TSPEAR
508737,21:46003160:G>A,NM_144991.2:c.83-15271C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,3.012,0.0008,1KG_AFR_AF,TSPEAR
508738,21:46003161:G>A,NM_144991.2:c.83-15272C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,2.665,\N,\N,TSPEAR
508739,21:46003192:ATTC>A,NM_144991.2:c.83-15306_83-15304del,\N,\N,1/11,Benign,\N,intron_variant,5.125,0.028,1KG_AFR_AF,TSPEAR
508740,21:46003242:C>T,NM_144991.2:c.83-15353G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,2.504,0.0014,1KG_AMR_AF,TSPEAR
508741,21:46003243:G>A,NM_144991.2:c.83-15354C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.163,0.001,1KG_EAS_AF,TSPEAR
508742,21:46003273:C>T,NM_144991.2:c.83-15384G>A,\N,\N,1/11,Benign,\N,intron_variant,3.088,0.0567,1KG_AFR_AF,TSPEAR
508743,21:46003274:G>A,NM_144991.2:c.83-15385C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.293,\N,\N,TSPEAR
508744,21:46003306:A>G,NM_144991.2:c.83-15417T>C,\N,\N,1/11,Unknown significance,\N,intron_variant,5.152,0.0029,1KG_AMR_AF,TSPEAR
508745,21:46003335:G>A,NM_144991.2:c.83-15446C>T,\N,\N,1/11,Benign,\N,intron_variant,0.226,0.0136,1KG_AFR_AF,TSPEAR
508746,21:46003345:G>A,NM_144991.2:c.83-15456C>T,\N,\N,1/11,Benign,\N,intron_variant,0.241,0.005,1KG_EAS_AF,TSPEAR
508747,21:46003360:GT>G,NM_144991.2:c.83-15472del,\N,\N,1/11,Benign,\N,intron_variant,1.888,0.0089,1KG_EAS_AF,TSPEAR
508748,21:46003362:C>T,NM_144991.2:c.83-15473G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.11,\N,\N,TSPEAR
508749,21:46003378:C>G,NM_144991.2:c.83-15489G>C,\N,\N,1/11,Benign,\N,intron_variant,1.544,0.0446,1KG_AFR_AF,TSPEAR
508750,21:46003379:G>A,NM_144991.2:c.83-15490C>T,\N,\N,1/11,Benign,\N,intron_variant,0.236,0.0401,1KG_AFR_AF,TSPEAR
508751,21:46003381:G>A,NM_144991.2:c.83-15492C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,2.147,0.0014,1KG_AMR_AF,TSPEAR
508752,21:46003393:T>G,NM_144991.2:c.83-15504A>C,\N,\N,1/11,Benign,\N,intron_variant,1.356,0.0265,1KG_AFR_AF,TSPEAR
508753,21:46003439:GGAGT>G,NM_144991.2:c.83-15554_83-15551del,\N,\N,1/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
508754,21:46003527:G>A,NM_144991.2:c.83-15638C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,10.32,\N,\N,TSPEAR
508755,21:46003531:A>ATAGT,NM_144991.2:c.83-15646_83-15643dup,\N,\N,1/11,Benign,\N,intron_variant,6.858,0.034,1KG_AFR_AF,TSPEAR
508756,21:46003545:C>G,NM_144991.2:c.83-15656G>C,\N,\N,1/11,Unknown significance,\N,intron_variant,9.379,\N,\N,TSPEAR
508757,21:46003576:T>C,NM_144991.2:c.83-15687A>G,\N,\N,1/11,Benign,\N,intron_variant,3.751,0.0219,1KG_AFR_AF,TSPEAR
508758,21:46003595:T>C,NM_144991.2:c.83-15706A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,4.095,\N,\N,TSPEAR
508759,21:46003606:C>T,NM_144991.2:c.83-15717G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.294,0.0008,1KG_AFR_AF,TSPEAR
508760,21:46003612:C>T,NM_144991.2:c.83-15723G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,1.816,0.001,1KG_EAS_AF,TSPEAR
508761,21:46003623:C>T,NM_144991.2:c.83-15734G>A,\N,\N,1/11,Benign,\N,intron_variant,1.832,0.1964,1KG_EAS_AF,TSPEAR
508762,21:46003624:G>A,NM_144991.2:c.83-15735C>T,\N,\N,1/11,Benign,\N,intron_variant,0.095,0.0363,1KG_AFR_AF,TSPEAR
508763,21:46003639:G>A,NM_144991.2:c.83-15750C>T,\N,\N,1/11,Benign,\N,intron_variant,0.194,0.034,1KG_AFR_AF,TSPEAR
508764,21:46003668:T>C,NM_144991.2:c.83-15779A>G,\N,\N,1/11,Benign,\N,intron_variant,0.095,0.1964,1KG_EAS_AF,TSPEAR
508765,21:46003682:G>GTGA,NM_144991.2:c.83-15796_83-15794dup,\N,\N,1/11,Benign,\N,intron_variant,6.675,0.4304,1KG_AFR_AF,TSPEAR
508766,21:46003684:G>A,NM_144991.2:c.83-15795C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,8.265,0.0008,1KG_AFR_AF,TSPEAR
508767,21:46003686:T>TTGA,NM_144991.2:c.83-15798_83-15797insTCA,\N,\N,1/11,Unknown significance,\N,intron_variant,\N,\N,\N,TSPEAR
508768,21:46003693:G>A,NM_144991.2:c.83-15804C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,10.61,0.0008,1KG_AFR_AF,TSPEAR
508769,21:46003771:G>C,NM_144991.2:c.83-15882C>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.235,\N,\N,TSPEAR
508770,21:46003790:C>T,NM_144991.2:c.83-15901G>A,\N,\N,1/11,Benign,\N,intron_variant,0.827,0.233,1KG_AFR_AF,TSPEAR
508771,21:46003797:T>A,NM_144991.2:c.83-15908A>T,\N,\N,1/11,Unknown significance,\N,intron_variant,2.219,0.001,1KG_EAS_AF,TSPEAR
508772,21:46003806:A>T,NM_144991.2:c.83-15917T>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.326,0.0008,1KG_AFR_AF,TSPEAR
508773,21:46003880:T>C,NM_144991.2:c.83-15991A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.559,\N,\N,TSPEAR
508774,21:46003900:G>A,NM_144991.2:c.83-16011C>T,\N,\N,1/11,Benign,\N,intron_variant,0.24,0.1964,1KG_EAS_AF,TSPEAR
508775,21:46003919:C>T,NM_144991.2:c.83-16030G>A,\N,\N,1/11,Benign,\N,intron_variant,3.89,0.0333,1KG_AFR_AF,TSPEAR
508776,21:46003935:C>T,NM_144991.2:c.83-16046G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,1.251,\N,\N,TSPEAR
508777,21:46004000:C>T,NM_144991.2:c.83-16111G>A,\N,\N,1/11,Benign,\N,intron_variant,4.32,0.233,1KG_AFR_AF,TSPEAR
508778,21:46004022:C>T,NM_144991.2:c.83-16133G>A,\N,\N,1/11,Unknown significance,\N,intron_variant,0.447,0.0014,1KG_AMR_AF,TSPEAR
508779,21:46004035:T>C,NM_144991.2:c.83-16146A>G,\N,\N,1/11,Unknown significance,\N,intron_variant,0.023,0.001,1KG_EAS_AF,TSPEAR
508780,21:46004060:C>A,NM_144991.2:c.83-16171G>T,\N,\N,1/11,Benign,\N,intron_variant,2.72,0.0089,1KG_EUR_AF,TSPEAR
508781,21:46004062:G>A,NM_144991.2:c.83-16173C>T,\N,\N,1/11,Unknown significance,\N,intron_variant,0.503,0.001